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PRJNA195909:zebrafish embryo and larva development

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Results for mafa+mafbb

Z-value: 1.90

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Transcription factors associated with mafa+mafbb

Gene Symbol Gene ID Gene Info
mafa
ENSDARG00000015890 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
mafbb
ENSDARG00000070542 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb
mafbb
ENSDARG00000099120 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafadr11_v1_chr18_+_29402623_294026230.933.3e-04Click!
mafbbdr11_v1_chr11_-_25384213_253842130.491.8e-01Click!

Activity profile of mafa+mafbb motif

Sorted Z-values of mafa+mafbb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31277415 6.58 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr6_-_13783604 4.79 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
cryba2a
crystallin, beta A2a
chr5_-_67471375 4.62 ENSDART00000147009
si:dkey-251i10.2
si:dkey-251i10.2
chr8_+_31435452 4.06 ENSDART00000145282
selenop
selenoprotein P
chr16_+_46294337 3.94 ENSDART00000040769
nr2f5
nuclear receptor subfamily 2, group F, member 5
chr15_-_29388012 3.57 ENSDART00000115032
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr2_-_24554416 3.52 ENSDART00000052061
cnn2
calponin 2
chr5_-_30615901 3.51 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr19_+_7567763 3.44 ENSDART00000140411
s100a11
S100 calcium binding protein A11
chr18_+_22302635 3.44 ENSDART00000141051
carmil2
capping protein regulator and myosin 1 linker 2
chr13_+_2908764 3.19 ENSDART00000162362
wu:fj16a03
wu:fj16a03
chr20_-_14054083 3.16 ENSDART00000009549
rhag
Rh associated glycoprotein
chr11_-_5865744 2.98 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr13_-_23007813 2.80 ENSDART00000057638
hk1
hexokinase 1
chr9_-_22076368 2.78 ENSDART00000128486
crygm2a
crystallin, gamma M2a
chr23_+_24124684 2.76 ENSDART00000144478
si:dkey-21o19.2
si:dkey-21o19.2
chr12_+_16967715 2.74 ENSDART00000138174
slc16a12b
solute carrier family 16, member 12b
chr10_-_39011514 2.72 ENSDART00000075123
pcp4a
Purkinje cell protein 4a
chr9_-_22318511 2.61 ENSDART00000129295
crygm2d2
crystallin, gamma M2d2
chr14_+_34547554 2.59 ENSDART00000074819
gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
chr10_+_10801564 2.47 ENSDART00000027026
ambp
alpha-1-microglobulin/bikunin precursor
chr3_-_18030938 2.41 ENSDART00000013540
si:ch73-141c7.1
si:ch73-141c7.1
chr8_-_41228530 2.37 ENSDART00000165949
ENSDART00000173055
fahd2a
fumarylacetoacetate hydrolase domain containing 2A
chr10_+_10801719 2.34 ENSDART00000193648
ambp
alpha-1-microglobulin/bikunin precursor
chr4_-_16341801 2.34 ENSDART00000140190
kera
keratocan
chr2_+_25816843 2.33 ENSDART00000078639
slc2a2
solute carrier family 2 (facilitated glucose transporter), member 2
chr24_-_12938922 2.32 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr23_-_26077038 2.28 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr23_-_31428763 2.26 ENSDART00000053545
zgc:153284
zgc:153284
chr2_-_30611389 2.22 ENSDART00000142500
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr19_+_31771270 2.17 ENSDART00000147474
stmn2b
stathmin 2b
chr15_-_29387446 2.11 ENSDART00000145976
ENSDART00000035096
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr1_-_12278522 2.00 ENSDART00000142122
ENSDART00000003825
cplx2l
complexin 2, like
chr20_-_20613584 1.83 ENSDART00000140991
si:ch211-253p18.2
si:ch211-253p18.2
chr21_-_28523548 1.83 ENSDART00000077910
epdl2
ependymin-like 2
chr1_+_19303241 1.74 ENSDART00000129970
si:dkeyp-118a3.2
si:dkeyp-118a3.2
chr6_-_40744720 1.72 ENSDART00000154916
ENSDART00000186922
p4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr18_+_14595805 1.72 ENSDART00000167825
wfdc1
WAP four-disulfide core domain 1
chr12_-_3940768 1.70 ENSDART00000134292
zgc:92040
zgc:92040
chr16_+_13855039 1.70 ENSDART00000113764
ENSDART00000143983
zgc:174888
zgc:174888
chr8_-_50287949 1.69 ENSDART00000023639
nkx2.7
NK2 transcription factor related 7
chr7_+_39386982 1.69 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr5_-_65004791 1.66 ENSDART00000180023
ANXA1 (1 of many)
zgc:110283
chr5_-_65004578 1.56 ENSDART00000169287
ANXA1 (1 of many)
zgc:110283
chr11_-_33960318 1.56 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr24_+_3307857 1.53 ENSDART00000106527
gyg1b
glycogenin 1b
chr14_+_34780886 1.51 ENSDART00000130469
ENSDART00000188806
ENSDART00000172924
ENSDART00000173266
ENSDART00000166377
ENSDART00000173371
sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr16_-_12319822 1.48 ENSDART00000127453
ENSDART00000184526
trpv6
transient receptor potential cation channel, subfamily V, member 6
chr13_+_29773153 1.47 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
pax2a
paired box 2a
chr11_+_23265157 1.45 ENSDART00000110152
csf1a
colony stimulating factor 1a (macrophage)
chr10_+_31222433 1.44 ENSDART00000185080
tmem218
transmembrane protein 218
chr1_+_54766943 1.38 ENSDART00000144759
nlrc6
NLR family CARD domain containing 6
chr20_-_16972351 1.38 ENSDART00000148312
ENSDART00000186702
si:ch73-74h11.1
si:ch73-74h11.1
chr16_+_7662609 1.38 ENSDART00000184895
ENSDART00000149404
ENSDART00000081418
ENSDART00000081422
bves
blood vessel epicardial substance
chr6_-_48087152 1.33 ENSDART00000180614
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr1_-_30457062 1.30 ENSDART00000185318
ENSDART00000157924
ENSDART00000161380
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr22_-_24285432 1.27 ENSDART00000164083
si:ch211-117l17.4
si:ch211-117l17.4
chr4_+_47257854 1.27 ENSDART00000173868
crestin
crestin
chr11_-_40128722 1.26 ENSDART00000165781
fam83e
family with sequence similarity 83, member E
chr1_-_30510839 1.24 ENSDART00000168189
ENSDART00000174868
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr2_-_9748039 1.24 ENSDART00000134870
si:ch1073-170o4.1
si:ch1073-170o4.1
chr9_-_12624622 1.20 ENSDART00000146535
tspearb
thrombospondin-type laminin G domain and EAR repeats b
chr21_-_5393125 1.19 ENSDART00000146061
psmd5
proteasome 26S subunit, non-ATPase 5
chr23_+_42304602 1.18 ENSDART00000166004
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr10_+_38708099 1.18 ENSDART00000172306
tmprss2
transmembrane protease, serine 2
chr7_+_63325819 1.16 ENSDART00000085612
ENSDART00000161436
pcdh7b
protocadherin 7b
chr18_-_8885792 1.14 ENSDART00000143619
si:dkey-95h12.1
si:dkey-95h12.1
chr23_-_19500559 1.14 ENSDART00000177414
ENSDART00000145898
asb14b
ankyrin repeat and SOCS box containing 14b
chr7_+_23875269 1.11 ENSDART00000101406
rab39bb
RAB39B, member RAS oncogene family b
chr19_-_9711472 1.09 ENSDART00000016197
ENSDART00000175075
slc2a3a
solute carrier family 2 (facilitated glucose transporter), member 3a
chr21_+_21374277 1.03 ENSDART00000079431
rtn2b
reticulon 2b
chr1_-_52498146 1.00 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr13_-_20381485 1.00 ENSDART00000131351
si:ch211-270n8.1
si:ch211-270n8.1
chr23_-_20764227 0.98 ENSDART00000089750
znf362b
zinc finger protein 362b
chr21_+_45496442 0.97 ENSDART00000164880
si:dkey-223p19.1
si:dkey-223p19.1
chr2_-_3038904 0.97 ENSDART00000186795
guk1a
guanylate kinase 1a
chr14_-_4076480 0.97 ENSDART00000059231
enpp6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr19_+_1465004 0.95 ENSDART00000159157
CABZ01073736.1

chr4_-_58964138 0.95 ENSDART00000150259
si:ch211-64i20.3
si:ch211-64i20.3
chr9_-_23850978 0.95 ENSDART00000132915
serpine3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr17_-_20236228 0.93 ENSDART00000136490
ENSDART00000029380
bnip4
BCL2 interacting protein 4
chr23_-_29376859 0.92 ENSDART00000146411
sst6
somatostatin 6
chr1_-_5745420 0.91 ENSDART00000166779
nrp2a
neuropilin 2a
chr13_+_36770738 0.89 ENSDART00000146696
atl1
atlastin GTPase 1
chr24_+_22022109 0.88 ENSDART00000133686
ropn1l
rhophilin associated tail protein 1-like
chr20_-_23852174 0.88 ENSDART00000122414
si:dkey-15j16.6
si:dkey-15j16.6
chr22_-_10354381 0.81 ENSDART00000092050
stab1
stabilin 1
chr7_+_42460302 0.80 ENSDART00000004120
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr23_+_7379728 0.80 ENSDART00000012194
gata5
GATA binding protein 5
chr21_-_11820379 0.78 ENSDART00000126640
RHOBTB3
si:dkey-6b12.5
chr11_-_36263886 0.78 ENSDART00000140397
nfya
nuclear transcription factor Y, alpha
chr9_+_38372216 0.76 ENSDART00000141895
plcd4b
phospholipase C, delta 4b
chr17_-_53353653 0.76 ENSDART00000180744
ENSDART00000026879
unm_sa911
un-named sa911
chr1_-_26131088 0.75 ENSDART00000193973
ENSDART00000054209
cdkn2a/b
cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4)
chr8_-_554540 0.73 ENSDART00000163934
FO704758.1
Danio rerio uncharacterized LOC100329294 (LOC100329294), mRNA.
chr24_+_22021675 0.73 ENSDART00000081234
ropn1l
rhophilin associated tail protein 1-like
chr9_-_55586151 0.72 ENSDART00000181886
arsh
arylsulfatase H
chr12_+_46608361 0.70 ENSDART00000189164
FADS6
fatty acid desaturase 6
chr8_-_7847921 0.68 ENSDART00000188094
zgc:113363
zgc:113363
chr1_-_10847753 0.67 ENSDART00000141052
dmd
dystrophin
chr5_-_43959972 0.67 ENSDART00000180517
si:ch211-204c21.1
si:ch211-204c21.1
chr20_-_29420713 0.64 ENSDART00000147464
ryr3
ryanodine receptor 3
chr18_+_33725576 0.64 ENSDART00000146816
si:dkey-145c18.5
si:dkey-145c18.5
chr16_-_31435020 0.63 ENSDART00000138508
zgc:194210
zgc:194210
chr4_+_9609905 0.62 ENSDART00000142284
ENSDART00000150687
meig1
meiosis/spermiogenesis associated 1
chr7_-_25697285 0.61 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr1_+_31054915 0.61 ENSDART00000148968
itga6b
integrin, alpha 6b
chr1_-_52497834 0.60 ENSDART00000136469
ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr9_+_13985567 0.60 ENSDART00000102296
cd28
CD28 molecule
chr18_-_45617146 0.60 ENSDART00000146543
wt1b
wilms tumor 1b
chr20_+_18741089 0.59 ENSDART00000183218
fam167ab
family with sequence similarity 167, member Ab
chr17_+_51262556 0.59 ENSDART00000186748
ENSDART00000181606
ENSDART00000063738
ENSDART00000189066
eipr1
EARP complex and GARP complex interacting protein 1
chr1_+_8601935 0.58 ENSDART00000152367
si:ch211-160d14.6
si:ch211-160d14.6
chr9_-_8670158 0.55 ENSDART00000077296
col4a1
collagen, type IV, alpha 1
chr19_-_35428815 0.55 ENSDART00000169006
ENSDART00000003167
ak2
adenylate kinase 2
chr24_-_42090635 0.54 ENSDART00000166413
ssr1
signal sequence receptor, alpha
chr4_+_77709678 0.54 ENSDART00000036856
AL935186.1

chr16_-_44349845 0.54 ENSDART00000170932
rims2a
regulating synaptic membrane exocytosis 2a
chr7_+_38811800 0.52 ENSDART00000052322
zgc:110699
zgc:110699
chr10_+_8527196 0.52 ENSDART00000141147
si:ch211-193e13.5
si:ch211-193e13.5
chr7_-_19043401 0.51 ENSDART00000158796
fcer1g
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr9_+_14291932 0.51 ENSDART00000183119
BX511082.1

chr10_+_26747755 0.50 ENSDART00000100329
f9b
coagulation factor IXb
chr24_+_41940299 0.50 ENSDART00000022349
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr5_-_31035198 0.47 ENSDART00000086534
cyb5d2
cytochrome b5 domain containing 2
chr16_-_49781481 0.47 ENSDART00000127513
znf385d
zinc finger protein 385D
chr1_+_50613868 0.47 ENSDART00000111114
HERC5
si:ch73-190m4.1
chr15_-_47838391 0.47 ENSDART00000180337
kbtbd3
kelch repeat and BTB (POZ) domain containing 3
chr16_-_51299061 0.46 ENSDART00000148677
serpinb1l4
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr13_-_33153889 0.45 ENSDART00000141451
TC2N
tandem C2 domains, nuclear
chr23_-_44494401 0.43 ENSDART00000114640
ENSDART00000148532
actl6b
actin-like 6B
chr20_-_20932760 0.42 ENSDART00000152415
ENSDART00000039907
btbd6b
BTB (POZ) domain containing 6b
chr4_+_77195833 0.39 ENSDART00000188365
si:dkey-172k15.6
si:dkey-172k15.6
chr8_+_23436411 0.38 ENSDART00000140044
foxp3b
forkhead box P3b
chr22_-_4892937 0.38 ENSDART00000147002
si:ch73-256j6.4
si:ch73-256j6.4
chr4_-_57340828 0.37 ENSDART00000193689
zgc:194906
zgc:194906
chr5_+_38684651 0.37 ENSDART00000137852
si:dkey-58f10.10
si:dkey-58f10.10
chr21_+_45659525 0.34 ENSDART00000160391
slc22a5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr20_+_18661624 0.34 ENSDART00000152136
ENSDART00000126959
tnfaip2a
tumor necrosis factor, alpha-induced protein 2a
chr20_-_20410029 0.33 ENSDART00000192177
ENSDART00000063483
prkchb
protein kinase C, eta, b
chr7_+_57108823 0.32 ENSDART00000184943
ENSDART00000055956
enosf1
enolase superfamily member 1
chr19_+_32947910 0.32 ENSDART00000052091
atp6v1c1b
ATPase H+ transporting V1 subunit C1b
chr25_+_19955598 0.30 ENSDART00000091547
kcna1a
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr4_+_65057234 0.30 ENSDART00000162985
si:dkey-14o6.2
si:dkey-14o6.2
chr11_-_23501467 0.29 ENSDART00000169066
plekha6
pleckstrin homology domain containing, family A member 6
chr20_-_8304271 0.29 ENSDART00000179057
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr4_-_67909331 0.29 ENSDART00000191908
si:ch211-66c13.1
si:ch211-66c13.1
chr5_+_9377005 0.29 ENSDART00000124924
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr20_+_46385907 0.28 ENSDART00000060710
adgrg11
adhesion G protein-coupled receptor G11
chr21_-_43328056 0.28 ENSDART00000114955
sowahaa
sosondowah ankyrin repeat domain family member Aa
chr15_+_45640906 0.27 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr7_+_34790768 0.27 ENSDART00000075116
si:dkey-148a17.6
si:dkey-148a17.6
chr5_-_30475011 0.26 ENSDART00000187501
phldb1a
pleckstrin homology-like domain, family B, member 1a
chr24_+_12983434 0.26 ENSDART00000145214
ENSDART00000146911
ENSDART00000066700
eloca
elongin C paralog a
chr14_-_24001825 0.25 ENSDART00000130704
il4
interleukin 4
chr15_+_3790556 0.25 ENSDART00000181467
RNF14 (1 of many)
ring finger protein 14
chr5_-_54160809 0.24 ENSDART00000158981
arhgef15
Rho guanine nucleotide exchange factor (GEF) 15
chr13_-_25199260 0.23 ENSDART00000057605
adka
adenosine kinase a
chr7_+_50053339 0.23 ENSDART00000174308
LRRC4C (1 of many)
si:dkey-6l15.1
chr2_-_9059955 0.22 ENSDART00000022768
ak5
adenylate kinase 5
chr8_-_14052349 0.22 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr22_-_25469751 0.22 ENSDART00000171670
CR769772.4

chr9_+_6802641 0.20 ENSDART00000187278
FO203514.1

chr17_-_31044803 0.20 ENSDART00000185941
ENSDART00000152016
eml1
echinoderm microtubule associated protein like 1
chr17_-_19345521 0.20 ENSDART00000082085
gsc
goosecoid
chr20_-_39219537 0.19 ENSDART00000005764
cyp39a1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr15_-_33818872 0.19 ENSDART00000158325
n4bp2l2
NEDD4 binding protein 2-like 2
chr15_+_21202820 0.18 ENSDART00000154036
si:dkey-52d15.2
si:dkey-52d15.2
chr15_+_1116664 0.17 ENSDART00000154780
p2ry12
purinergic receptor P2Y12
chr17_-_50422584 0.16 ENSDART00000157095
si:ch211-235i11.5
si:ch211-235i11.5
chr17_-_53359028 0.16 ENSDART00000185218
CABZ01068208.1

chr23_-_44848961 0.15 ENSDART00000136839
wu:fb72h05
wu:fb72h05
chr2_+_38373272 0.15 ENSDART00000113111
psmb5
proteasome subunit beta 5
chr3_+_57788761 0.15 ENSDART00000149741
si:ch73-362i18.1
si:ch73-362i18.1
chr1_-_7582859 0.15 ENSDART00000110696
mxb
myxovirus (influenza) resistance B
chr16_-_30564319 0.14 ENSDART00000145087
lmna
lamin A
chr5_+_19413838 0.14 ENSDART00000089014
ENSDART00000146215
myo1ha
myosin IHa
chr4_+_42878556 0.13 ENSDART00000171047
si:zfos-451d2.2
si:zfos-451d2.2
chr3_+_23063718 0.13 ENSDART00000140225
ENSDART00000184431
b4galnt2.1
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 1
chr24_-_23998897 0.13 ENSDART00000130053
zmp:0000000991
zmp:0000000991
chr5_+_38679623 0.12 ENSDART00000131879
ENSDART00000170010
si:dkey-58f10.11
si:dkey-58f10.10
si:dkey-58f10.11
si:dkey-58f10.10
chr8_+_36621598 0.12 ENSDART00000180389
magixb
MAGI family member, X-linked b
chr19_+_23308419 0.11 ENSDART00000141558
irgf2
immunity-related GTPase family, f2
chr16_+_17089114 0.11 ENSDART00000173223
cd27
CD27 molecule
chr4_-_71708855 0.11 ENSDART00000158819
si:dkeyp-4f2.1
si:dkeyp-4f2.1
chr11_+_43401201 0.11 ENSDART00000190128
vipb
vasoactive intestinal peptide b
chr13_+_25199849 0.09 ENSDART00000139209
ENSDART00000130876
ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr12_-_44043285 0.09 ENSDART00000163074
si:ch211-182p11.1
si:ch211-182p11.1
chr6_-_33924883 0.09 ENSDART00000132762
ENSDART00000148142
ENSDART00000142213
akr1a1b
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr6_+_43390387 0.09 ENSDART00000122793
mitfa
microphthalmia-associated transcription factor a
chr4_+_54645654 0.09 ENSDART00000192864
si:ch211-227e10.1
si:ch211-227e10.1
chr2_+_42260021 0.09 ENSDART00000124702
ENSDART00000140203
ENSDART00000184079
ENSDART00000193349
ftr04
finTRIM family, member 4
chr8_-_13177536 0.08 ENSDART00000100992
zgc:194990
zgc:194990
chr12_-_44019561 0.07 ENSDART00000165900
si:dkey-31i7.1
si:dkey-31i7.1
chr15_+_41932069 0.07 ENSDART00000143007
si:ch211-191a16.2
si:ch211-191a16.2
chr6_+_58569808 0.07 ENSDART00000154393
helz2
helicase with zinc finger 2, transcriptional coactivator
chr2_+_17525355 0.07 ENSDART00000074101
pimr196
Pim proto-oncogene, serine/threonine kinase, related 196
chr17_+_6217704 0.07 ENSDART00000129100
BX000363.1

chr4_-_71708567 0.07 ENSDART00000182645
si:dkeyp-4f2.1
si:dkeyp-4f2.1
chr4_-_39448829 0.06 ENSDART00000168526
si:dkey-261o4.9
si:dkey-261o4.9

Network of associatons between targets according to the STRING database.

First level regulatory network of mafa+mafbb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.8 3.2 GO:0015840 urea transport(GO:0015840)
0.7 4.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.6 2.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.6 2.3 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.4 1.5 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.3 1.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 1.0 GO:0019695 choline metabolic process(GO:0019695)
0.3 1.4 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.2 0.5 GO:1904861 excitatory synapse assembly(GO:1904861)
0.2 3.4 GO:0030011 maintenance of cell polarity(GO:0030011)
0.2 2.8 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.2 0.8 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.2 1.6 GO:0048240 sperm capacitation(GO:0048240)
0.2 0.8 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.2 1.5 GO:0021588 cerebellum formation(GO:0021588)
0.2 8.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 0.6 GO:0042117 plasma membrane repair(GO:0001778) monocyte activation(GO:0042117)
0.1 5.7 GO:0030199 collagen fibril organization(GO:0030199)
0.1 3.5 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.1 1.7 GO:0003207 cardiac chamber formation(GO:0003207)
0.1 3.9 GO:0032526 response to retinoic acid(GO:0032526)
0.1 0.9 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 4.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.7 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 0.3 GO:0002369 T cell cytokine production(GO:0002369)
0.1 1.7 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.9 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 1.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.5 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 10.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 2.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.3 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.0 2.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.9 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 2.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.6 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.2 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.0 0.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 1.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 1.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 2.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 2.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.9 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.3 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.1 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.6 GO:0031100 organ regeneration(GO:0031100)
0.0 0.8 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.6 GO:0051208 sequestering of calcium ion(GO:0051208) release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283)
0.0 1.2 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 2.3 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.6 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 1.4 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.0 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.0 1.9 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.2 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.0 0.4 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 1.6 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.7 GO:0001558 regulation of cell growth(GO:0001558)
0.0 1.3 GO:0002040 sprouting angiogenesis(GO:0002040)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.3 GO:0005861 troponin complex(GO:0005861)
0.2 0.5 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.1 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 2.0 GO:0043195 terminal bouton(GO:0043195)
0.1 2.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.4 GO:0030057 desmosome(GO:0030057)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.6 GO:0030315 T-tubule(GO:0030315)
0.0 2.2 GO:0030426 growth cone(GO:0030426)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 0.3 GO:0044224 paranode region of axon(GO:0033270) juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.6 GO:0031514 motile cilium(GO:0031514)
0.0 2.4 GO:0014069 postsynaptic density(GO:0014069)
0.0 3.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.5 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 1.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.5 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 22.5 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.1 GO:0008430 selenium binding(GO:0008430)
0.8 2.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.5 3.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.5 2.8 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 1.7 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 3.1 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.3 0.6 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.3 2.4 GO:0048039 ubiquinone binding(GO:0048039)
0.2 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 0.5 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.1 5.7 GO:0005518 collagen binding(GO:0005518)
0.1 1.6 GO:0004046 aminoacylase activity(GO:0004046)
0.1 3.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.7 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.6 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 10.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 3.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.4 GO:0030552 cAMP binding(GO:0030552)
0.1 2.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 2.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 2.3 GO:0030145 manganese ion binding(GO:0030145)
0.1 6.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 2.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 3.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 1.7 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 3.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.1 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 6.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 3.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 2.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 3.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 3.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases