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PRJNA195909:zebrafish embryo and larva development

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Results for mecp2

Z-value: 1.34

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Transcription factors associated with mecp2

Gene Symbol Gene ID Gene Info
mecp2
ENSDARG00000014218 methyl CpG binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mecp2dr11_v1_chr8_-_7637626_76376400.916.6e-04Click!

Activity profile of mecp2 motif

Sorted Z-values of mecp2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_55758103 1.71 ENSDART00000185964
CT583728.23

chr9_-_32158288 1.53 ENSDART00000037182
ankrd44
ankyrin repeat domain 44
chr5_-_825920 1.45 ENSDART00000126982
zgc:158463
zgc:158463
chr4_+_3438510 1.38 ENSDART00000155320
atxn7l1
ataxin 7-like 1
chr4_-_77561679 1.29 ENSDART00000180809
AL935186.9

chr11_+_42422371 1.29 ENSDART00000163780
dennd6aa
DENN/MADD domain containing 6Aa
chr19_-_47587719 1.27 ENSDART00000111108
CABZ01071972.1

chr19_-_27830818 1.27 ENSDART00000131767
papd7
PAP associated domain containing 7
chr5_-_30382925 1.21 ENSDART00000125381
gig2o
grass carp reovirus (GCRV)-induced gene 2o
chr17_-_27235797 1.21 ENSDART00000130080
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr8_+_48966165 1.14 ENSDART00000165425
aak1a
AP2 associated kinase 1a
chr12_+_24060894 1.12 ENSDART00000021298
asb3
ankyrin repeat and SOCS box containing 3
chr8_+_48965767 1.08 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr23_+_553396 1.08 ENSDART00000034707
lsm14b
LSM family member 14B
chr20_+_32523576 1.01 ENSDART00000147319
scml4
Scm polycomb group protein like 4
chr23_-_32156278 1.01 ENSDART00000157479
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr7_-_51773166 1.00 ENSDART00000054591
bmp15
bone morphogenetic protein 15
chr23_+_28128453 0.99 ENSDART00000182618
c1galt1a
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr19_+_41479990 0.99 ENSDART00000087187
ago2
argonaute RISC catalytic component 2
chr17_+_52300018 0.99 ENSDART00000190302
esrrb
estrogen-related receptor beta
chr2_-_38287987 0.97 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
si:ch211-14a17.6
chr23_-_44819100 0.93 ENSDART00000076373
st8sia7.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 7.1
chr18_+_18000695 0.93 ENSDART00000146898
si:ch211-212o1.2
si:ch211-212o1.2
chr9_-_32343673 0.92 ENSDART00000078499
rftn2
raftlin family member 2
chr11_+_42422638 0.90 ENSDART00000042599
ENSDART00000181175
dennd6aa
DENN/MADD domain containing 6Aa
chr7_+_16348835 0.90 ENSDART00000002449
mpped2a
metallophosphoesterase domain containing 2a
chr13_-_44782462 0.90 ENSDART00000141298
ENSDART00000099990
btbd9
BTB (POZ) domain containing 9
chr1_-_23308225 0.88 ENSDART00000137567
ENSDART00000008201
smim14
small integral membrane protein 14
chr19_-_11846958 0.88 ENSDART00000148516
ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr11_+_39969048 0.87 ENSDART00000193693
per3
period circadian clock 3
chr21_+_13233377 0.87 ENSDART00000142569
specc1lb
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr10_-_9115383 0.87 ENSDART00000139324
si:dkeyp-41f9.3
si:dkeyp-41f9.3
chr11_-_25853212 0.86 ENSDART00000145655
tmem51b
transmembrane protein 51b
chr19_+_14454306 0.86 ENSDART00000161965
zdhhc18b
zinc finger, DHHC-type containing 18b
chr16_-_42066523 0.85 ENSDART00000180538
ENSDART00000058620
zp3d.1
zona pellucida glycoprotein 3d tandem duplicate 1
chr23_+_43668756 0.85 ENSDART00000112598
otud4
OTU deubiquitinase 4
chr3_+_35005062 0.83 ENSDART00000181163
prkcbb
protein kinase C, beta b
chr15_-_47895200 0.83 ENSDART00000027060
DMWD
zmp:0000000529
chr15_+_38299563 0.82 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr20_-_51547464 0.82 ENSDART00000099486
disp1
dispatched homolog 1 (Drosophila)
chr15_-_30815826 0.81 ENSDART00000156160
ENSDART00000145918
msi2b
musashi RNA-binding protein 2b
chr20_-_52939501 0.81 ENSDART00000166508
fdft1
farnesyl-diphosphate farnesyltransferase 1
chr21_-_2814709 0.81 ENSDART00000097664
SEMA4D
semaphorin 4D
chr19_+_13994563 0.80 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr5_-_9216758 0.76 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr21_-_13751535 0.75 ENSDART00000111666
npdc1a
neural proliferation, differentiation and control, 1a
chr10_+_39476600 0.75 ENSDART00000135756
kirrel3a
kirre like nephrin family adhesion molecule 3a
chr8_-_22739757 0.73 ENSDART00000182167
ENSDART00000171891
iqsec2a
IQ motif and Sec7 domain 2a
chr5_+_45140914 0.71 ENSDART00000172702
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_-_135774 0.70 ENSDART00000160435
FQ377903.1

chr15_+_23208042 0.70 ENSDART00000006085
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr20_+_474288 0.69 ENSDART00000026794
nt5dc1
5'-nucleotidase domain containing 1
chr6_+_41554794 0.69 ENSDART00000165424
srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr10_+_10972795 0.66 ENSDART00000127331
cdc37l1
cell division cycle 37-like 1
chr9_+_17787864 0.66 ENSDART00000013111
dgkh
diacylglycerol kinase, eta
chr3_+_14463941 0.65 ENSDART00000170927
cnn1b
calponin 1, basic, smooth muscle, b
chr1_-_55248496 0.65 ENSDART00000098615
nanos3
nanos homolog 3
chr2_+_25657958 0.64 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr7_+_32021669 0.62 ENSDART00000173976
mettl15
methyltransferase like 15
chr2_+_25658112 0.61 ENSDART00000051234
tnika
TRAF2 and NCK interacting kinase a
chr25_+_2776511 0.61 ENSDART00000115280
neo1b
neogenin 1b
chr23_-_2037566 0.61 ENSDART00000191312
ENSDART00000127443
prdm5
PR domain containing 5
chr11_-_27917730 0.60 ENSDART00000173219
eif4g3a
eukaryotic translation initiation factor 4 gamma, 3a
chr17_+_43629008 0.60 ENSDART00000184185
ENSDART00000181681
znf365
zinc finger protein 365
chr16_-_43317927 0.60 ENSDART00000164472
washc5
WASH complex subunit 5
chr8_+_50190742 0.59 ENSDART00000099863
slc25a37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr20_-_16078741 0.59 ENSDART00000021550
ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr17_-_20202725 0.58 ENSDART00000133650
ecd
ecdysoneless homolog (Drosophila)
chr15_+_45595385 0.58 ENSDART00000161937
ENSDART00000170214
ENSDART00000157450
atg16l1
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr21_-_30031396 0.57 ENSDART00000157167
pwwp2a
PWWP domain containing 2A
chr19_-_31576321 0.57 ENSDART00000103612
tdp2b
tyrosyl-DNA phosphodiesterase 2b
chr17_-_23709347 0.57 ENSDART00000124661
papss2a
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr18_+_18405992 0.57 ENSDART00000080174
n4bp1
nedd4 binding protein 1
chr12_-_13730501 0.57 ENSDART00000152370
foxh1
forkhead box H1
chr25_+_4581214 0.56 ENSDART00000185552
CABZ01068600.1

chr12_-_13966184 0.56 ENSDART00000066368
klhl11
kelch-like family member 11
chr8_+_23165749 0.56 ENSDART00000063057
dnajc5aa
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr7_+_53254234 0.55 ENSDART00000169830
trip4
thyroid hormone receptor interactor 4
chr5_-_24712405 0.55 ENSDART00000033630
si:ch211-106a19.1
si:ch211-106a19.1
chr4_-_12102025 0.55 ENSDART00000048391
ENSDART00000023894
braf
B-Raf proto-oncogene, serine/threonine kinase
chr5_+_15992655 0.55 ENSDART00000182148
znrf3
zinc and ring finger 3
chr18_+_50961953 0.54 ENSDART00000158768
ppfia1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
chr3_-_10582384 0.54 ENSDART00000048095
ENSDART00000155152
elac2
elaC ribonuclease Z 2
chr11_+_2687395 0.54 ENSDART00000082510
b3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr3_+_48842918 0.53 ENSDART00000159420
hs3st3b1a
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a
chr4_+_23223881 0.53 ENSDART00000133056
ENSDART00000089126
trhde.1
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr18_-_399554 0.53 ENSDART00000164374
ENSDART00000186311
ENSDART00000181816
ENSDART00000181892
si:ch211-79l17.1
si:ch211-79l17.1
chr17_+_43926523 0.53 ENSDART00000121550
ENSDART00000041447
ktn1
kinectin 1
chr7_-_33829824 0.53 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr8_+_14915332 0.52 ENSDART00000164385
abl2
c-abl oncogene 2, non-receptor tyrosine kinase
chr8_+_18555559 0.52 ENSDART00000149523
tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr11_-_45171139 0.52 ENSDART00000167036
ENSDART00000161712
ENSDART00000158156
syngr2b
synaptogyrin 2b
chr10_+_31809226 0.52 ENSDART00000087898
foxo1b
forkhead box O1 b
chr20_+_34502606 0.52 ENSDART00000139739
gorab
golgin, rab6-interacting
chr24_+_24285751 0.51 ENSDART00000122294
ythdf3
YTH N(6)-methyladenosine RNA binding protein 3
chr14_+_35024521 0.50 ENSDART00000158634
ENSDART00000170631
ebf3a
early B cell factor 3a
chr16_-_13388821 0.50 ENSDART00000144062
grin2db
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr11_-_20987378 0.50 ENSDART00000110140
taf4a
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr14_-_27289042 0.49 ENSDART00000159727
pcdh11
protocadherin 11
chr15_-_34558579 0.49 ENSDART00000140882
ispd
isoprenoid synthase domain containing
chr3_-_27880229 0.49 ENSDART00000151404
abat
4-aminobutyrate aminotransferase
chr12_+_4220353 0.49 ENSDART00000133675
mapk7
mitogen-activated protein kinase 7
chr10_-_33156789 0.49 ENSDART00000192268
ENSDART00000182065
ENSDART00000081170
cux1a
cut-like homeobox 1a
chr15_-_25367309 0.48 ENSDART00000047471
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr23_+_12361899 0.48 ENSDART00000143728
pigt
phosphatidylinositol glycan anchor biosynthesis, class T
chr8_+_47897734 0.47 ENSDART00000140266
mfn2
mitofusin 2
chr10_-_32494304 0.47 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr21_-_14692119 0.47 ENSDART00000123047
ehmt1b
euchromatic histone-lysine N-methyltransferase 1b
chr2_+_23222939 0.47 ENSDART00000026800
kifap3b
kinesin-associated protein 3b
chr2_+_54327160 0.47 ENSDART00000182320
LO018508.1

chr2_+_39108339 0.46 ENSDART00000085675
clstn2
calsyntenin 2
chr19_+_232536 0.46 ENSDART00000137880
syngap1a
synaptic Ras GTPase activating protein 1a
chr19_+_32979331 0.46 ENSDART00000078066
spire1a
spire-type actin nucleation factor 1a
chr25_+_33972019 0.45 ENSDART00000188515
ENSDART00000121498
ice2
interactor of little elongator complex ELL subunit 2
chr1_+_15258641 0.45 ENSDART00000033018
pi4k2b
phosphatidylinositol 4-kinase type 2 beta
chr4_-_12930086 0.45 ENSDART00000013604
lemd3
LEM domain containing 3
chr7_+_1442059 0.45 ENSDART00000173391
si:cabz01090193.1
si:cabz01090193.1
chr14_+_25505468 0.45 ENSDART00000079016
thoc3
THO complex 3
chr21_-_25613249 0.44 ENSDART00000137896
fibpb
fibroblast growth factor (acidic) intracellular binding protein b
chr5_+_69950882 0.44 ENSDART00000097359
dnajc25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr8_+_1843135 0.44 ENSDART00000141452
snap29
synaptosomal-associated protein 29
chr6_-_36795111 0.43 ENSDART00000160669
ENSDART00000104256
ENSDART00000187751
ENSDART00000161928
ENSDART00000183264
opa1
optic atrophy 1 (autosomal dominant)
chr21_-_11367271 0.43 ENSDART00000151000
ENSDART00000151465
zgc:162472
zgc:162472
chr21_+_10021823 0.43 ENSDART00000163995
herc7
hect domain and RLD 7
chr15_+_45994123 0.43 ENSDART00000124704
lrfn1
leucine rich repeat and fibronectin type III domain containing 1
chr14_-_6402769 0.43 ENSDART00000121552
slc44a1b
solute carrier family 44 (choline transporter), member 1b
chr20_+_46699021 0.43 ENSDART00000167398
ENSDART00000029894
wdr26b
WD repeat domain 26b
chr3_+_20001608 0.43 ENSDART00000137944
asb16
ankyrin repeat and SOCS box containing 16
chr8_+_2757821 0.43 ENSDART00000051403
ENSDART00000160551
sh3glb2a
SH3-domain GRB2-like endophilin B2a
chr23_+_20431140 0.43 ENSDART00000193950
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr13_-_36525982 0.42 ENSDART00000114744
pacs2
phosphofurin acidic cluster sorting protein 2
chr19_-_9503473 0.42 ENSDART00000091615
iffo1a
intermediate filament family orphan 1a
chr25_-_12203952 0.42 ENSDART00000158204
ENSDART00000091727
ntrk3a
neurotrophic tyrosine kinase, receptor, type 3a
chr15_-_34871968 0.42 ENSDART00000191980
mgat1a
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr15_+_44093286 0.42 ENSDART00000114352
zgc:112998
zgc:112998
chr16_+_42471455 0.41 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr1_+_52632856 0.41 ENSDART00000011725
slc44a1a
solute carrier family 44 (choline transporter), member 1a
chr2_-_9744081 0.41 ENSDART00000097732
dvl3a
dishevelled segment polarity protein 3a
chr12_-_33789006 0.41 ENSDART00000034550
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr16_-_2807527 0.41 ENSDART00000148927
tgfb2
transforming growth factor, beta 2
chr20_+_30702531 0.41 ENSDART00000062525
acbd3
acyl-Coenzyme A binding domain containing 3
chr10_-_6588793 0.40 ENSDART00000163788
chd1
chromodomain helicase DNA binding protein 1
chr3_+_22059066 0.40 ENSDART00000155739
kansl1b
KAT8 regulatory NSL complex subunit 1b
chr18_-_21910991 0.40 ENSDART00000089787
ENSDART00000169220
ENSDART00000132381
ENSDART00000191764
edc4
enhancer of mRNA decapping 4
chr22_-_4398069 0.40 ENSDART00000181893
kdm4b
lysine (K)-specific demethylase 4B
chr12_-_18961289 0.40 ENSDART00000168405
ep300a
E1A binding protein p300 a
chr3_-_13461056 0.39 ENSDART00000137678
fbxw9
F-box and WD repeat domain containing 9
chr3_+_17653784 0.39 ENSDART00000159984
ENSDART00000157682
ENSDART00000187937
kat2a
K(lysine) acetyltransferase 2A
chr22_+_1006573 0.39 ENSDART00000123458
pparda
peroxisome proliferator-activated receptor delta a
chr11_-_21363834 0.39 ENSDART00000080051
RASSF5
si:dkey-85p17.3
chr12_+_33038757 0.39 ENSDART00000153146
rbfox3a
RNA binding fox-1 homolog 3a
chr13_+_14006118 0.39 ENSDART00000131875
ENSDART00000089528
atrn
attractin
chr13_-_36566260 0.38 ENSDART00000030133
synj2bp
synaptojanin 2 binding protein
chr23_+_10426219 0.38 ENSDART00000139100
eif4ba
eukaryotic translation initiation factor 4Ba
chr13_-_36911118 0.38 ENSDART00000048739
trim9
tripartite motif containing 9
chr15_+_30158652 0.37 ENSDART00000190682
nlk2
nemo-like kinase, type 2
chr7_+_1534820 0.37 ENSDART00000192997
tox4b
TOX high mobility group box family member 4 b
chr11_+_41459408 0.37 ENSDART00000182285
park7
parkinson protein 7
chr23_+_20431388 0.37 ENSDART00000132920
ENSDART00000102963
ENSDART00000109899
ENSDART00000140219
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr18_-_33344 0.37 ENSDART00000129125
pde8a
phosphodiesterase 8A
chr9_+_1505206 0.36 ENSDART00000093427
ENSDART00000137230
pde11a
phosphodiesterase 11a
chr12_+_36428052 0.36 ENSDART00000131300
unk
unkempt family zinc finger
chr10_-_41156348 0.36 ENSDART00000058622
aak1b
AP2 associated kinase 1b
chr9_-_52206336 0.36 ENSDART00000114222
tanc1b
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1b
chr7_+_41887429 0.36 ENSDART00000115090
gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr16_+_33953644 0.36 ENSDART00000164447
ENSDART00000159969
arid1aa
AT rich interactive domain 1Aa (SWI-like)
chr15_+_39096736 0.36 ENSDART00000129511
ENSDART00000014877
robo2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr1_+_40613297 0.35 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr20_-_3276339 0.35 ENSDART00000166831
rps6kc1
ribosomal protein S6 kinase polypeptide 1
chr19_-_7441686 0.35 ENSDART00000168194
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr14_-_38946808 0.35 ENSDART00000139293
gla
galactosidase, alpha
chr13_-_24745288 0.34 ENSDART00000031564
sfr1
SWI5-dependent homologous recombination repair protein 1
chr10_+_43037064 0.33 ENSDART00000160159
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr14_+_46118834 0.33 ENSDART00000124417
ENSDART00000017785
naa15a
N(alpha)-acetyltransferase 15, NatA auxiliary subunit a
chr3_-_13068189 0.33 ENSDART00000167180
prkar1b
protein kinase, cAMP-dependent, regulatory, type I, beta
chr17_-_50010121 0.33 ENSDART00000122747
tmem30aa
transmembrane protein 30Aa
chr15_-_45110011 0.33 ENSDART00000182047
ENSDART00000188662
CABZ01072607.1

chr12_-_33789218 0.33 ENSDART00000193258
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr16_+_32136550 0.33 ENSDART00000147526
sphk2
sphingosine kinase 2
chr2_-_37401600 0.33 ENSDART00000015723
prkci
protein kinase C, iota
chr13_+_11876437 0.33 ENSDART00000179753
trim8a
tripartite motif containing 8a
chr5_+_4016271 0.32 ENSDART00000113627
ENSDART00000105832
ENSDART00000121415
ggnbp2
gametogenetin binding protein 2
chr16_+_27345383 0.32 ENSDART00000078250
ENSDART00000162857
nr4a3
nuclear receptor subfamily 4, group A, member 3
chr16_-_12914288 0.32 ENSDART00000184221
cacng8b
calcium channel, voltage-dependent, gamma subunit 8b
chr8_-_11131695 0.32 ENSDART00000055742
nras
NRAS proto-oncogene, GTPase
chr3_-_25054002 0.32 ENSDART00000086768
ep300b
E1A binding protein p300 b
chr2_+_51645164 0.32 ENSDART00000169600
abhd4
abhydrolase domain containing 4
chr21_-_30030644 0.32 ENSDART00000190810
CU855895.2

chr19_+_47301893 0.32 ENSDART00000051695
tpmt.1
thiopurine S-methyltransferase, tandem duplicate 1
chr5_-_22573624 0.32 ENSDART00000131889
ENSDART00000080886
ENSDART00000147513
ENSDART00000080882
aifm1
apoptosis-inducing factor, mitochondrion-associated 1
chr18_-_46369516 0.32 ENSDART00000018163
irf2bp1
interferon regulatory factor 2 binding protein 1
chr24_+_5208171 0.32 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
si:ch73-206p6.1
chr7_+_5906327 0.32 ENSDART00000173160
zgc:112234
zgc:112234
chr6_+_33931740 0.31 ENSDART00000130492
ENSDART00000151213
orc1
origin recognition complex, subunit 1
chr2_-_43739740 0.31 ENSDART00000113849
kif5ba
kinesin family member 5B, a
chr19_+_3056450 0.31 ENSDART00000141324
ENSDART00000082353
hsf1
heat shock transcription factor 1
chr7_+_32021982 0.31 ENSDART00000173848
mettl15
methyltransferase like 15
chr7_-_73851280 0.31 ENSDART00000190053
FP236812.3

chr6_-_59357256 0.30 ENSDART00000074534
fam210b
family with sequence similarity 210, member B
chr3_+_1211242 0.30 ENSDART00000171287
ENSDART00000165769
poldip3
polymerase (DNA-directed), delta interacting protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of mecp2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0008344 adult locomotory behavior(GO:0008344)
0.3 0.9 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 0.9 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.3 1.0 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.2 1.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 0.8 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 1.0 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 0.6 GO:0034036 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 0.6 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.2 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 0.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 0.2 GO:0007618 mating(GO:0007618)
0.2 0.6 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 2.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 1.3 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.7 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 0.5 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.5 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.1 0.5 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.1 0.4 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.1 0.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.6 GO:0039694 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.1 1.8 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.8 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.5 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.9 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.3 GO:0072388 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.4 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 0.2 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 0.5 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.5 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.1 0.4 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.3 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.4 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.8 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 0.5 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.2 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 0.4 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 1.0 GO:0007032 endosome organization(GO:0007032)
0.0 0.3 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.5 GO:0050779 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.4 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.6 GO:0061055 myotome development(GO:0061055)
0.0 0.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.4 GO:0061056 sclerotome development(GO:0061056)
0.0 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.7 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.6 GO:0051567 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.1 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.0 0.3 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.5 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.4 GO:1903010 regulation of bone development(GO:1903010)
0.0 0.1 GO:1905132 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.0 0.2 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.6 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700) regulation of lymphangiogenesis(GO:1901490)
0.0 0.7 GO:0050821 protein stabilization(GO:0050821)
0.0 0.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 1.4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.6 GO:0009408 response to heat(GO:0009408)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.4 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.1 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.3 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.2 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.0 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0032988 ribosome disassembly(GO:0032790) ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:1901998 toxin transport(GO:1901998)
0.0 1.4 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.4 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.7 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 1.0 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.6 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0030728 ovulation(GO:0030728)
0.0 0.0 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0043113 receptor clustering(GO:0043113)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 0.6 GO:0071203 WASH complex(GO:0071203)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.5 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.6 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.2 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 0.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0035060 brahma complex(GO:0035060)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0016234 inclusion body(GO:0016234)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.9 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0035032 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.5 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.2 GO:0016586 RSC complex(GO:0016586)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 2.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.8 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.4 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.0 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 1.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.4 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.3 0.8 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 1.0 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 1.0 GO:0070883 pre-miRNA binding(GO:0070883)
0.2 0.7 GO:0047690 aspartyltransferase activity(GO:0047690)
0.2 2.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.6 GO:0030882 lipid antigen binding(GO:0030882)
0.2 0.6 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.2 0.6 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.5 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.4 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.8 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.3 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.3 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.3 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.8 GO:0032190 acrosin binding(GO:0032190)
0.1 0.3 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.3 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.6 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.4 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.8 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.5 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.7 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.5 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0008483 transaminase activity(GO:0008483)
0.0 0.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.7 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID IGF1 PATHWAY IGF1 pathway
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.9 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis