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PRJNA195909:zebrafish embryo and larva development

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Results for mef2b

Z-value: 1.32

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Transcription factors associated with mef2b

Gene Symbol Gene ID Gene Info
mef2b
ENSDARG00000093170 myocyte enhancer factor 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2bdr11_v1_chr22_+_18188045_181880450.462.1e-01Click!

Activity profile of mef2b motif

Sorted Z-values of mef2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_61205711 5.10 ENSDART00000055062
pvalb1
parvalbumin 1
chr3_-_32818607 4.18 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr25_+_29160102 3.38 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr11_+_11201096 2.85 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr9_-_33107237 2.70 ENSDART00000013918
casq2
calsequestrin 2
chr5_-_72125551 2.65 ENSDART00000149412
smyd1a
SET and MYND domain containing 1a
chr16_+_29663809 2.41 ENSDART00000191336
tmod4
tropomodulin 4 (muscle)
chr6_-_42003780 2.39 ENSDART00000032527
cav3
caveolin 3
chr5_+_51597677 2.31 ENSDART00000048210
ENSDART00000184797
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr23_+_20110086 2.12 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr10_-_8032885 2.04 ENSDART00000188619
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr20_-_26001288 1.90 ENSDART00000136518
ENSDART00000063177
capn3b
calpain 3b
chr8_+_22930627 1.85 ENSDART00000187860
sypa
synaptophysin a
chr13_+_9432501 1.85 ENSDART00000058064
zgc:123321
zgc:123321
chr10_-_22803740 1.84 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
pcolcea
procollagen C-endopeptidase enhancer a
chr6_-_14139503 1.81 ENSDART00000089577
cacnb4b
calcium channel, voltage-dependent, beta 4b subunit
chr10_-_8033468 1.76 ENSDART00000140476
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr17_-_10025234 1.76 ENSDART00000008355
cfl2
cofilin 2 (muscle)
chr1_+_45080897 1.59 ENSDART00000129819
si:ch211-151p13.8
si:ch211-151p13.8
chr23_+_22658700 1.53 ENSDART00000192248
eno1a
enolase 1a, (alpha)
chr9_+_31795343 1.52 ENSDART00000139584
itgbl1
integrin, beta-like 1
chr17_-_12336987 1.48 ENSDART00000172001
snap25b
synaptosomal-associated protein, 25b
chr5_+_67390645 1.41 ENSDART00000014822
ebf2
early B cell factor 2
chr10_+_37145007 1.38 ENSDART00000131777
cuedc1a
CUE domain containing 1a
chr20_-_26042070 1.37 ENSDART00000140255
si:dkey-12h9.6
si:dkey-12h9.6
chr5_-_36948586 1.33 ENSDART00000193606
h3f3c
H3 histone, family 3C
chr10_-_24371312 1.33 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr20_+_15552657 1.29 ENSDART00000063912
jun
Jun proto-oncogene, AP-1 transcription factor subunit
chr1_+_10683843 1.26 ENSDART00000054879
zgc:103678
zgc:103678
chr8_+_29962635 1.24 ENSDART00000007640
ptch1
patched 1
chr12_+_6002715 1.24 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr4_-_23908802 1.19 ENSDART00000138873
celf2
cugbp, Elav-like family member 2
chr19_-_41069573 1.19 ENSDART00000111982
ENSDART00000193142
sgce
sarcoglycan, epsilon
chr1_-_25936677 1.17 ENSDART00000146488
ENSDART00000136321
myoz2b
myozenin 2b
chr5_-_31875645 1.16 ENSDART00000098160
tmem119b
transmembrane protein 119b
chr5_+_67390115 1.15 ENSDART00000193255
ebf2
early B cell factor 2
chr7_+_14291323 1.15 ENSDART00000053521
rhcga
Rh family, C glycoprotein a
chr14_+_24215046 1.15 ENSDART00000079215
stc2a
stanniocalcin 2a
chr25_+_3677650 1.14 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr10_-_22845485 1.12 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr5_+_64368770 1.09 ENSDART00000162246
plpp7
phospholipid phosphatase 7 (inactive)
chr21_+_19070921 1.06 ENSDART00000029874
nkx6.1
NK6 homeobox 1
chr20_+_34455645 1.02 ENSDART00000135789
mettl11b
methyltransferase like 11B
chr19_-_38611814 1.01 ENSDART00000151958
col16a1
collagen, type XVI, alpha 1
chr24_-_32665283 1.00 ENSDART00000038364
ca2
carbonic anhydrase II
chr24_-_20444844 1.00 ENSDART00000048940
vill
villin-like
chr24_+_25471196 1.00 ENSDART00000066625
smpx
small muscle protein, X-linked
chr11_-_18253111 0.99 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr12_+_8373525 0.95 ENSDART00000152180
arid5b
AT-rich interaction domain 5B
chr1_+_8601935 0.95 ENSDART00000152367
si:ch211-160d14.6
si:ch211-160d14.6
chr19_+_41169996 0.93 ENSDART00000048438
asb4
ankyrin repeat and SOCS box containing 4
chr25_-_13381854 0.91 ENSDART00000164621
ENSDART00000169129
ndrg4
NDRG family member 4
chr5_-_51819027 0.88 ENSDART00000164267
homer1b
homer scaffolding protein 1b
chr23_+_23485858 0.84 ENSDART00000114067
agrn
agrin
chr7_-_27686021 0.82 ENSDART00000079112
ENSDART00000100989
calca
calcitonin/calcitonin-related polypeptide, alpha
chr10_-_4980150 0.81 ENSDART00000093228
mat2al
methionine adenosyltransferase II, alpha-like
chr21_-_12272543 0.78 ENSDART00000081510
ENSDART00000151297
celf4
CUGBP, Elav-like family member 4
chr12_-_34035364 0.76 ENSDART00000087065
timp2a
TIMP metallopeptidase inhibitor 2a
chr6_-_10780698 0.75 ENSDART00000151714
gpr155b
G protein-coupled receptor 155b
chr14_+_35901249 0.74 ENSDART00000105604
zgc:77938
zgc:77938
chr6_-_40722200 0.73 ENSDART00000035101
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr2_-_33993533 0.73 ENSDART00000140910
ENSDART00000077304
ptch2
patched 2
chr6_-_40722480 0.72 ENSDART00000188187
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr14_-_32405387 0.69 ENSDART00000184647
fgf13a
fibroblast growth factor 13a
chr24_+_8736497 0.66 ENSDART00000181904
tmem14ca
transmembrane protein 14Ca
chr23_-_39849155 0.65 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr7_-_7420301 0.65 ENSDART00000102620
six7
SIX homeobox 7
chr12_+_34119439 0.63 ENSDART00000032821
cyth1b
cytohesin 1b
chr1_-_17569793 0.63 ENSDART00000125125
acsl1a
acyl-CoA synthetase long chain family member 1a
chr8_-_25002182 0.62 ENSDART00000078792
ahcyl1
adenosylhomocysteinase-like 1
chr11_-_39202915 0.62 ENSDART00000105133
wnt4a
wingless-type MMTV integration site family, member 4a
chr12_+_30563550 0.60 ENSDART00000126064
si:ch211-28p3.4
si:ch211-28p3.4
chr1_-_44638058 0.59 ENSDART00000081835
slc43a1b
solute carrier family 43 (amino acid system L transporter), member 1b
chr13_-_50139916 0.59 ENSDART00000099475
nid1a
nidogen 1a
chr23_+_44614056 0.55 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr1_-_411331 0.54 ENSDART00000092524
rasa3
RAS p21 protein activator 3
chr22_+_9772754 0.54 ENSDART00000130194
BX664625.2

chr7_-_23745984 0.54 ENSDART00000048050
ITGB1BP2
zgc:92429
chr13_+_42011287 0.54 ENSDART00000131147
cyp1b1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr3_+_23092762 0.53 ENSDART00000142884
ENSDART00000024136
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr17_-_13026634 0.53 ENSDART00000113713
fam177a1
family with sequence similarity 177, member A1
chr8_+_44420108 0.53 ENSDART00000075381
CU571323.1

chr2_+_19777146 0.52 ENSDART00000038648
ptbp2b
polypyrimidine tract binding protein 2b
chr14_-_24332786 0.52 ENSDART00000173164
fam13b
family with sequence similarity 13, member B
chr14_+_21107032 0.51 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldob
aldolase b, fructose-bisphosphate
chr6_-_35472923 0.49 ENSDART00000185907
rgs8
regulator of G protein signaling 8
chr2_+_1202347 0.48 ENSDART00000075837
CABZ01084566.1

chr10_+_29259882 0.48 ENSDART00000180606
sytl2a
synaptotagmin-like 2a
chr5_+_64842730 0.46 ENSDART00000144732
lrrc8ab
leucine rich repeat containing 8 VRAC subunit Ab
chr25_-_21816269 0.46 ENSDART00000152014
zgc:158222
zgc:158222
chr21_+_11685009 0.45 ENSDART00000014668
pcsk1
proprotein convertase subtilisin/kexin type 1
chr22_+_26443235 0.44 ENSDART00000044085
zgc:92480
zgc:92480
chr1_-_25177086 0.44 ENSDART00000144711
ENSDART00000177225
tmem154
transmembrane protein 154
chr17_+_6956696 0.44 ENSDART00000171368
zgc:172341
zgc:172341
chr12_+_42400277 0.44 ENSDART00000166590
si:ch211-221j21.3
si:ch211-221j21.3
chr16_+_16969060 0.43 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
rpl18
si:ch211-120k19.1
ribosomal protein L18
chr5_-_10946232 0.43 ENSDART00000163139
ENSDART00000031265
rtn4r
reticulon 4 receptor
chr21_+_11684830 0.42 ENSDART00000147473
pcsk1
proprotein convertase subtilisin/kexin type 1
chr1_-_17570013 0.42 ENSDART00000146946
acsl1a
acyl-CoA synthetase long chain family member 1a
chr16_+_16968682 0.42 ENSDART00000111074
si:ch211-120k19.1
si:ch211-120k19.1
chr12_-_36740781 0.41 ENSDART00000105484
si:ch211-216b21.2
si:ch211-216b21.2
chr21_+_12010505 0.40 ENSDART00000123522
aqp7
aquaporin 7
chr15_-_14552101 0.40 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr10_+_29260096 0.40 ENSDART00000088973
sytl2a
synaptotagmin-like 2a
chr9_-_48281941 0.40 ENSDART00000099787
klhl41a
kelch-like family member 41a
chr8_+_17987215 0.40 ENSDART00000113605
lrriq3
leucine-rich repeats and IQ motif containing 3
chr9_-_48937240 0.39 ENSDART00000075627
cers6
ceramide synthase 6
chr7_-_52334840 0.38 ENSDART00000174173
CR938716.1

chr24_-_4450238 0.38 ENSDART00000066835
fzd8a
frizzled class receptor 8a
chr8_-_50259448 0.37 ENSDART00000146056
nkx3-1
NK3 homeobox 1
chr21_-_25669820 0.36 ENSDART00000148236
tmem179b
transmembrane protein 179B
chr12_+_41697664 0.36 ENSDART00000162302
bnip3
BCL2 interacting protein 3
chr24_-_12745222 0.36 ENSDART00000151836
si:ch211-196f5.9
si:ch211-196f5.9
chr17_+_6957042 0.34 ENSDART00000103839
zgc:172341
zgc:172341
chr2_+_37975026 0.34 ENSDART00000034802
si:rp71-1g18.13
si:rp71-1g18.13
chr21_+_25669934 0.32 ENSDART00000101203
sumf2
sulfatase modifying factor 2
chr1_-_21483832 0.32 ENSDART00000102790
glrba
glycine receptor, beta a
chr10_+_29698467 0.31 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr19_-_31035155 0.30 ENSDART00000161882
bzw2
basic leucine zipper and W2 domains 2
chr19_+_24394560 0.28 ENSDART00000142506
si:dkey-81h8.1
si:dkey-81h8.1
chr12_-_26430507 0.27 ENSDART00000153214
synpo2lb
synaptopodin 2-like b
chr3_-_52674089 0.27 ENSDART00000154260
ENSDART00000125455
si:dkey-210j14.4
si:dkey-210j14.4
chr1_-_6494384 0.26 ENSDART00000109356
klf7a
Kruppel-like factor 7a
chr23_+_44497701 0.25 ENSDART00000149903
si:ch73-375g18.1
si:ch73-375g18.1
chr16_-_17200120 0.24 ENSDART00000147739
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr25_-_29363934 0.24 ENSDART00000166889
nptna
neuroplastin a
chr18_+_7264961 0.23 ENSDART00000188461
CABZ01015105.1

chr4_-_5863906 0.22 ENSDART00000169424
slc5a8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr4_-_9637398 0.22 ENSDART00000150253
dclre1c
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr19_-_31035325 0.22 ENSDART00000147504
bzw2
basic leucine zipper and W2 domains 2
chr25_-_29988352 0.21 ENSDART00000067059
fam19a5b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5b
chr7_+_33457148 0.21 ENSDART00000133562
ENSDART00000074587
paqr5b
progestin and adipoQ receptor family member Vb
chr9_-_28399071 0.20 ENSDART00000104317
ENSDART00000064343
klf7b
Kruppel-like factor 7b
chr10_-_17170086 0.20 ENSDART00000020122
ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr25_-_27722614 0.20 ENSDART00000190154
zgc:153935
zgc:153935
chr20_-_26383368 0.19 ENSDART00000024518
ENSDART00000087844
esr1
estrogen receptor 1
chr6_-_46403475 0.19 ENSDART00000154148
camk1a
calcium/calmodulin-dependent protein kinase Ia
chr21_-_27185915 0.18 ENSDART00000135052
slc8a4a
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr4_+_5180650 0.17 ENSDART00000067390
fgf6b
fibroblast growth factor 6b
chr1_-_45662774 0.17 ENSDART00000042158
serhl
serine hydrolase-like
chr23_+_6077503 0.16 ENSDART00000081714
ENSDART00000139834
mybpha
myosin binding protein Ha
chr15_-_36347858 0.15 ENSDART00000155274
ENSDART00000157936
si:dkey-23k10.2
si:dkey-23k10.2
chr23_+_16889352 0.14 ENSDART00000145275
si:dkey-147f3.8
si:dkey-147f3.8
chr9_+_29040425 0.13 ENSDART00000150201
MRAS
si:ch73-116o1.2
chr23_-_25050329 0.13 ENSDART00000140216
avpr2aa
arginine vasopressin receptor 2a, duplicate a
chr18_+_40354998 0.13 ENSDART00000098791
ENSDART00000049171
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr19_-_32518556 0.12 ENSDART00000103410
zbtb8b
zinc finger and BTB domain containing 8B
chr25_-_27722309 0.12 ENSDART00000148121
zgc:153935
zgc:153935
chr17_-_15600455 0.11 ENSDART00000110272
ENSDART00000156911
si:ch211-266g18.9
si:ch211-266g18.9
chr21_+_43559123 0.11 ENSDART00000151212
gpr185a
G protein-coupled receptor 185 a
chr17_-_50234004 0.11 ENSDART00000058706
fosaa
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr4_+_77060861 0.10 ENSDART00000174271
ENSDART00000174393
ENSDART00000150450
si:dkey-240n22.8
si:dkey-240n22.8
chr7_+_21859337 0.10 ENSDART00000159626
si:dkey-85k7.7
si:dkey-85k7.7
chr17_-_14671098 0.10 ENSDART00000037371
ppp1r13ba
protein phosphatase 1, regulatory subunit 13Ba
chr22_-_26852516 0.09 ENSDART00000005829
gde1
glycerophosphodiester phosphodiesterase 1
chr19_+_44039849 0.09 ENSDART00000086040
lrrc14b
leucine rich repeat containing 14B
chr17_-_26867725 0.09 ENSDART00000153590
si:dkey-221l4.10
si:dkey-221l4.10
chr22_+_38310957 0.08 ENSDART00000040550
traf5
Tnf receptor-associated factor 5
chr24_+_26088143 0.08 ENSDART00000171129
CR352209.1

chr22_-_4769140 0.07 ENSDART00000165235
calr3a
calreticulin 3a
chr6_+_36942966 0.07 ENSDART00000028895
negr1
neuronal growth regulator 1
chr4_-_13509946 0.06 ENSDART00000134720
ifng1-2
interferon, gamma 1-2
chr23_-_7826849 0.06 ENSDART00000157612
myt1b
myelin transcription factor 1b
chr25_-_19486399 0.05 ENSDART00000155076
ENSDART00000156016
zgc:193812
zgc:193812
chr17_+_1992495 0.05 ENSDART00000192937
CABZ01062996.1

chr23_+_3721042 0.05 ENSDART00000143323
smim29
small integral membrane protein 29
chr17_+_45648836 0.05 ENSDART00000155037
zgc:162184
zgc:162184
chr5_-_50781623 0.03 ENSDART00000114950
zgc:194908
zgc:194908
chr5_+_44346691 0.03 ENSDART00000034523
tars
threonyl-tRNA synthetase
chr5_+_16580739 0.01 ENSDART00000135140
htr7c
5-hydroxytryptamine (serotonin) receptor 7c
chr4_+_14343706 0.01 ENSDART00000142845
prl2
prolactin 2
chr13_-_37647209 0.01 ENSDART00000189102
si:dkey-188i13.10
si:dkey-188i13.10
chr10_+_8688678 0.00 ENSDART00000147568
si:dkey-27b3.4
si:dkey-27b3.4
chr9_-_23894392 0.00 ENSDART00000133417
asb18
ankyrin repeat and SOCS box containing 18

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.6 1.9 GO:0097264 self proteolysis(GO:0097264)
0.6 1.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.4 1.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.3 1.0 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.3 0.8 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.3 1.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.3 3.8 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.3 2.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 2.4 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.3 2.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.3 2.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.3 1.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 1.1 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.2 2.0 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.2 1.0 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 2.3 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 2.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.4 GO:0060898 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 0.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.7 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.1 1.0 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.3 GO:0051597 response to methylmercury(GO:0051597)
0.1 1.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 1.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 4.1 GO:0006096 glycolytic process(GO:0006096)
0.1 1.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 1.0 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 0.5 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.1 0.9 GO:0016486 peptide hormone processing(GO:0016486)
0.1 2.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.5 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 1.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.6 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 1.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.8 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.2 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 1.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0042044 fluid transport(GO:0042044)
0.0 0.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.4 GO:0006936 muscle contraction(GO:0006936)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.4 3.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 6.5 GO:0031430 M band(GO:0031430)
0.3 2.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 1.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 1.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 4.5 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 1.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 2.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.4 GO:0030018 Z disc(GO:0030018)
0.0 0.7 GO:0030426 growth cone(GO:0030426)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0071253 connexin binding(GO:0071253)
0.6 3.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 2.0 GO:0097108 hedgehog family protein binding(GO:0097108)
0.3 1.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.3 0.8 GO:0031716 calcitonin receptor binding(GO:0031716)
0.3 2.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 3.8 GO:0051117 ATPase binding(GO:0051117)
0.2 0.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.8 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 1.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 2.3 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.1 1.0 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 1.2 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 4.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.5 GO:0070330 aromatase activity(GO:0070330)
0.1 1.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.4 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.0 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 2.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:1903924 estradiol binding(GO:1903924)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 4.6 GO:0051015 actin filament binding(GO:0051015)
0.0 13.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 1.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 2.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.9 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 1.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide