Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for mef2d

Z-value: 2.91

Motif logo

logo of

Transcription factors associated with mef2d

Gene Symbol Gene ID Gene Info
mef2d
ENSDARG00000040237 myocyte enhancer factor 2d

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2ddr11_v1_chr16_-_29194517_29194517-0.373.3e-01Click!

Activity profile of mef2d motif

Sorted Z-values of mef2d motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_7546259 10.16 ENSDART00000015732
mylz3
myosin, light polypeptide 3, skeletal muscle
chr3_-_61205711 9.04 ENSDART00000055062
pvalb1
parvalbumin 1
chr12_-_17712393 6.79 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr15_-_23645810 6.24 ENSDART00000168845
ckmb
creatine kinase, muscle b
chr11_+_11201096 6.17 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr23_+_20110086 6.10 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr25_+_29160102 5.40 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr24_-_24038800 5.12 ENSDART00000080549
lyz
lysozyme
chr9_-_33107237 5.03 ENSDART00000013918
casq2
calsequestrin 2
chr5_-_72125551 4.88 ENSDART00000149412
smyd1a
SET and MYND domain containing 1a
chr2_+_2737422 4.69 ENSDART00000032459
aqp1a.1
aquaporin 1a (Colton blood group), tandem duplicate 1
chr3_+_28953274 4.62 ENSDART00000133528
ENSDART00000103602
lgals2a
lectin, galactoside-binding, soluble, 2a
chr12_-_17707449 4.54 ENSDART00000142427
ENSDART00000034914
pvalb3
parvalbumin 3
chr16_+_29663809 4.53 ENSDART00000191336
tmod4
tropomodulin 4 (muscle)
chr21_+_28445052 4.53 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr4_-_9592402 4.47 ENSDART00000114060
cdnf
cerebral dopamine neurotrophic factor
chr12_-_26064105 4.34 ENSDART00000168825
ldb3b
LIM domain binding 3b
chr15_+_19652807 4.19 ENSDART00000134321
ENSDART00000054426
lim2.3
lens intrinsic membrane protein 2.3
chr8_+_7322465 4.18 ENSDART00000192380
ssuh2rs1
ssu-2 homolog, related sequence 1
chr16_-_31919568 4.05 ENSDART00000027364
rbfox1l
RNA binding fox-1 homolog 1, like
chr6_-_42003780 4.05 ENSDART00000032527
cav3
caveolin 3
chr7_+_31879649 4.03 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr1_+_19332837 3.96 ENSDART00000078594
tyrp1b
tyrosinase-related protein 1b
chr7_-_35708450 3.95 ENSDART00000193886
irx5a
iroquois homeobox 5a
chr11_+_11200550 3.86 ENSDART00000181339
ENSDART00000187116
myom2a
myomesin 2a
chr19_+_40983221 3.82 ENSDART00000144544
col1a2
collagen, type I, alpha 2
chr20_-_26001288 3.76 ENSDART00000136518
ENSDART00000063177
capn3b
calpain 3b
chr10_-_8032885 3.76 ENSDART00000188619
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr21_+_19070921 3.71 ENSDART00000029874
nkx6.1
NK6 homeobox 1
chr10_-_22803740 3.66 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
pcolcea
procollagen C-endopeptidase enhancer a
chr7_+_31879986 3.57 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr16_+_34523515 3.53 ENSDART00000041007
stmn1b
stathmin 1b
chr17_-_12336987 3.47 ENSDART00000172001
snap25b
synaptosomal-associated protein, 25b
chr8_+_22930627 3.47 ENSDART00000187860
sypa
synaptophysin a
chr10_-_8033468 3.29 ENSDART00000140476
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr15_+_40008370 3.24 ENSDART00000063783
itm2ca
integral membrane protein 2Ca
chr15_+_7176182 3.24 ENSDART00000101578
her8.2
hairy-related 8.2
chr9_+_17438765 3.22 ENSDART00000138953
rgcc
regulator of cell cycle
chr6_+_14949950 3.18 ENSDART00000149202
ENSDART00000149949
pou3f3b
POU class 3 homeobox 3b
chr14_-_11430566 3.14 ENSDART00000137154
ENSDART00000091158
irg1l
immunoresponsive gene 1, like
chr14_-_21064199 3.12 ENSDART00000172099
si:dkey-74k8.3
si:dkey-74k8.3
chr5_+_36932718 3.08 ENSDART00000037879
crx
cone-rod homeobox
chr10_-_29816467 3.07 ENSDART00000055913
hist2h2l
histone 2, H2, like
chr7_-_13381129 3.04 ENSDART00000164326
si:ch73-119p20.1
si:ch73-119p20.1
chr20_-_10118818 2.96 ENSDART00000033976
meis2b
Meis homeobox 2b
chr14_-_21063977 2.91 ENSDART00000164373
si:dkey-74k8.3
si:dkey-74k8.3
chr23_+_22658700 2.89 ENSDART00000192248
eno1a
enolase 1a, (alpha)
chr6_+_3680651 2.88 ENSDART00000013588
klhl41b
kelch-like family member 41b
chr5_+_51597677 2.84 ENSDART00000048210
ENSDART00000184797
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr14_-_30366196 2.76 ENSDART00000007022
pdgfrl
platelet-derived growth factor receptor-like
chr5_-_19394440 2.75 ENSDART00000163771
foxn4
forkhead box N4
chr12_+_6002715 2.74 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr5_+_67390645 2.73 ENSDART00000014822
ebf2
early B cell factor 2
chr11_-_18253111 2.72 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr15_+_47903864 2.69 ENSDART00000063835
otx5
orthodenticle homolog 5
chr16_+_26777473 2.69 ENSDART00000188870
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr5_-_36948586 2.66 ENSDART00000193606
h3f3c
H3 histone, family 3C
chr1_-_22678471 2.64 ENSDART00000128918
fgfbp1b
fibroblast growth factor binding protein 1b
chr10_-_24371312 2.59 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr20_+_15552657 2.57 ENSDART00000063912
jun
Jun proto-oncogene, AP-1 transcription factor subunit
chr2_-_16562505 2.56 ENSDART00000156406
atp1b3a
ATPase Na+/K+ transporting subunit beta 3a
chr21_-_22730832 2.54 ENSDART00000101797
fbxo40.1
F-box protein 40, tandem duplicate 1
chr20_-_40717900 2.52 ENSDART00000181663
cx43
connexin 43
chr9_+_31795343 2.50 ENSDART00000139584
itgbl1
integrin, beta-like 1
chr7_+_14291323 2.50 ENSDART00000053521
rhcga
Rh family, C glycoprotein a
chr9_-_34300707 2.49 ENSDART00000049805
ildr2
immunoglobulin-like domain containing receptor 2
chr8_-_32497815 2.45 ENSDART00000122359
si:dkey-164f24.2
si:dkey-164f24.2
chr6_+_57541776 2.43 ENSDART00000157330
necab3
N-terminal EF-hand calcium binding protein 3
chr13_+_22249636 2.41 ENSDART00000108472
ENSDART00000173123
synpo2la
synaptopodin 2-like a
chr19_+_5072918 2.40 ENSDART00000037126
eno2
enolase 2
chr7_-_28148310 2.37 ENSDART00000044208
lmo1
LIM domain only 1
chr17_-_10025234 2.36 ENSDART00000008355
cfl2
cofilin 2 (muscle)
chr16_-_22713152 2.34 ENSDART00000140953
ENSDART00000143836
si:ch211-105c13.3
si:ch211-105c13.3
chr1_+_10720294 2.29 ENSDART00000139387
atp1b1b
ATPase Na+/K+ transporting subunit beta 1b
chr10_+_26800213 2.29 ENSDART00000078996
arr3a
arrestin 3a, retinal (X-arrestin)
chr17_+_38566717 2.27 ENSDART00000145147
sptb
spectrin, beta, erythrocytic
chr4_+_19534833 2.26 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr12_+_16440708 2.25 ENSDART00000113810
ankrd1b
ankyrin repeat domain 1b (cardiac muscle)
chr7_-_40993456 2.24 ENSDART00000031700
en2a
engrailed homeobox 2a
chr5_+_67390115 2.22 ENSDART00000193255
ebf2
early B cell factor 2
chr23_+_23022790 2.18 ENSDART00000189843
samd11
sterile alpha motif domain containing 11
chr16_-_24518027 2.15 ENSDART00000134120
ENSDART00000143761
cadm4
cell adhesion molecule 4
chr17_-_21784152 2.12 ENSDART00000127254
hmx2
H6 family homeobox 2
chr3_+_59051503 2.10 ENSDART00000160767
rasd4
rasd family member 4
chr19_-_38611814 2.10 ENSDART00000151958
col16a1
collagen, type XVI, alpha 1
chr5_+_64368770 2.09 ENSDART00000162246
plpp7
phospholipid phosphatase 7 (inactive)
chr18_+_19974289 2.08 ENSDART00000090334
ENSDART00000192982
skor1b
SKI family transcriptional corepressor 1b
chr10_-_22845485 2.05 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr21_-_12272543 2.04 ENSDART00000081510
ENSDART00000151297
celf4
CUGBP, Elav-like family member 4
chr25_+_5039050 2.04 ENSDART00000154700
parvb
parvin, beta
chr23_-_23401305 2.04 ENSDART00000078936
her9
hairy-related 9
chr3_+_18398876 2.03 ENSDART00000141100
ENSDART00000138107
rps2
ribosomal protein S2
chr7_+_6969909 2.02 ENSDART00000189886
actn3b
actinin alpha 3b
chr2_+_29976419 2.02 ENSDART00000056748
en2b
engrailed homeobox 2b
chr10_+_32104305 2.02 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr10_+_22724059 1.99 ENSDART00000136123
kdm6bb
lysine (K)-specific demethylase 6B, b
chr13_-_11536951 1.98 ENSDART00000018155
adss
adenylosuccinate synthase
chr8_-_32497581 1.97 ENSDART00000176298
ENSDART00000183340
si:dkey-164f24.2
si:dkey-164f24.2
chr3_-_50046004 1.96 ENSDART00000109544
si:ch1073-100f3.2
si:ch1073-100f3.2
chr13_-_28674422 1.95 ENSDART00000122754
ENSDART00000057574
nt5c2a
5'-nucleotidase, cytosolic IIa
chr24_+_25471196 1.93 ENSDART00000066625
smpx
small muscle protein, X-linked
chr14_+_11430796 1.93 ENSDART00000165275
si:ch211-153b23.3
si:ch211-153b23.3
chr22_+_17205608 1.92 ENSDART00000181267
rab3b
RAB3B, member RAS oncogene family
chr24_+_20575259 1.91 ENSDART00000010488
klhl40b
kelch-like family member 40b
chr25_-_24074500 1.91 ENSDART00000040410
th
tyrosine hydroxylase
chr19_+_15571290 1.87 ENSDART00000131134
foxo6b
forkhead box O6 b
chr9_-_12424791 1.87 ENSDART00000135447
ENSDART00000088199
zgc:162707
zgc:162707
chr10_+_37145007 1.86 ENSDART00000131777
cuedc1a
CUE domain containing 1a
chr5_-_48268049 1.85 ENSDART00000187454
mef2cb
myocyte enhancer factor 2cb
chr5_-_51819027 1.85 ENSDART00000164267
homer1b
homer scaffolding protein 1b
chr3_+_18555899 1.84 ENSDART00000163036
ENSDART00000158791
cbx4
chromobox homolog 4 (Pc class homolog, Drosophila)
chr8_-_11112058 1.83 ENSDART00000042755
ampd1
adenosine monophosphate deaminase 1 (isoform M)
chr21_-_32487061 1.83 ENSDART00000114359
ENSDART00000131591
ENSDART00000131477
si:dkeyp-72g9.4
si:dkeyp-72g9.4
chr21_-_22737228 1.81 ENSDART00000151366
fbxo40.2
F-box protein 40, tandem duplicate 2
chr16_+_25761101 1.81 ENSDART00000110619
cblc
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr25_+_3677650 1.80 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr8_-_25002182 1.80 ENSDART00000078792
ahcyl1
adenosylhomocysteinase-like 1
chr3_+_18399315 1.78 ENSDART00000110842
rps2
ribosomal protein S2
chr17_+_42842632 1.77 ENSDART00000155547
ENSDART00000126087
qpct
glutaminyl-peptide cyclotransferase
chr10_+_29816681 1.76 ENSDART00000100022
h2afx1
H2A histone family member X1
chr14_-_24081929 1.76 ENSDART00000158576
msx2a
muscle segment homeobox 2a
chr1_+_8601935 1.73 ENSDART00000152367
si:ch211-160d14.6
si:ch211-160d14.6
chr23_+_23485858 1.72 ENSDART00000114067
agrn
agrin
chr22_-_906757 1.69 ENSDART00000193182
FP016205.1

chr14_+_24215046 1.69 ENSDART00000079215
stc2a
stanniocalcin 2a
chr21_+_12010505 1.69 ENSDART00000123522
aqp7
aquaporin 7
chr1_+_36674584 1.66 ENSDART00000186772
ENSDART00000192274
ednraa
endothelin receptor type Aa
chr9_+_6578580 1.65 ENSDART00000061577
fhl2a
four and a half LIM domains 2a
chr1_-_44638058 1.65 ENSDART00000081835
slc43a1b
solute carrier family 43 (amino acid system L transporter), member 1b
chr8_+_52637507 1.63 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr12_+_8373525 1.63 ENSDART00000152180
arid5b
AT-rich interaction domain 5B
chr25_-_21795930 1.62 ENSDART00000127033
ppp1r3ab
protein phosphatase 1, regulatory subunit 3Ab
chr22_-_31059670 1.61 ENSDART00000022445
cand2
cullin-associated and neddylation-dissociated 2 (putative)
chr10_+_8767541 1.60 ENSDART00000170272
itga1
integrin, alpha 1
chr7_-_7420301 1.58 ENSDART00000102620
six7
SIX homeobox 7
chr13_-_32635859 1.58 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matn3b
matrilin 3b
chr1_-_41982582 1.53 ENSDART00000014678
adra1d
adrenoceptor alpha 1D
chr24_+_38301080 1.52 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr7_+_25059845 1.52 ENSDART00000077215
ppp2r5b
protein phosphatase 2, regulatory subunit B', beta
chr5_-_63286077 1.52 ENSDART00000131274
tbcelb
tubulin folding cofactor E-like b
chr8_+_44703864 1.51 ENSDART00000016225
star
steroidogenic acute regulatory protein
chr1_-_25936677 1.51 ENSDART00000146488
ENSDART00000136321
myoz2b
myozenin 2b
chr7_-_33961551 1.47 ENSDART00000100104
skor1a
SKI family transcriptional corepressor 1a
chr14_+_38654300 1.46 ENSDART00000148938
ENSDART00000150107
rnasel3
ribonuclease like 3
chr9_-_41784799 1.44 ENSDART00000144573
ENSDART00000112542
ENSDART00000190486
obsl1b
obscurin-like 1b
chr14_-_7128980 1.44 ENSDART00000171311
si:ch73-43g23.1
si:ch73-43g23.1
chr21_+_34929598 1.44 ENSDART00000135806
si:dkey-71d15.2
si:dkey-71d15.2
chr9_+_44430974 1.44 ENSDART00000056846
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr11_-_39202915 1.42 ENSDART00000105133
wnt4a
wingless-type MMTV integration site family, member 4a
chr19_-_42566527 1.42 ENSDART00000147818
ENSDART00000142135
si:dkey-228a15.1
si:dkey-228a15.1
chr25_-_13381854 1.42 ENSDART00000164621
ENSDART00000169129
ndrg4
NDRG family member 4
chr24_-_20444844 1.42 ENSDART00000048940
vill
villin-like
chr21_-_22828593 1.42 ENSDART00000150993
angptl5
angiopoietin-like 5
chr21_-_25685739 1.41 ENSDART00000129619
ENSDART00000101205
phkg1b
phosphorylase kinase, gamma 1b (muscle)
chr25_+_13791627 1.40 ENSDART00000159278
zgc:92873
zgc:92873
chr12_+_30563550 1.39 ENSDART00000126064
si:ch211-28p3.4
si:ch211-28p3.4
chr19_-_42557416 1.38 ENSDART00000163217
ENSDART00000128278
ENSDART00000162304
ENSDART00000166556
si:dkey-267n13.1
si:dkey-267n13.1
chr21_-_22951604 1.38 ENSDART00000083449
ENSDART00000180129
dub
duboraya
chr22_+_16497670 1.37 ENSDART00000014330
ier5
immediate early response 5
chr13_+_1155536 1.37 ENSDART00000148356
perp
PERP, TP53 apoptosis effector
chr20_+_23173710 1.36 ENSDART00000074172
sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr23_-_39849155 1.35 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr20_+_19066858 1.35 ENSDART00000192086
sox7
SRY (sex determining region Y)-box 7
chr25_+_16945348 1.35 ENSDART00000016591
fgf6a
fibroblast growth factor 6a
chr14_-_32405387 1.34 ENSDART00000184647
fgf13a
fibroblast growth factor 13a
chr14_-_30704075 1.33 ENSDART00000134098
efemp2a
EGF containing fibulin extracellular matrix protein 2a
chr8_+_52701811 1.33 ENSDART00000179692
bcl2l16
BCL2 like 16
chr23_-_21515182 1.33 ENSDART00000142000
rnf207b
ring finger protein 207b
chr2_+_9552456 1.31 ENSDART00000056896
dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr19_-_24443867 1.31 ENSDART00000163763
ENSDART00000043133
thbs3b
thrombospondin 3b
chr19_-_48371092 1.29 ENSDART00000169464
rpl14
ribosomal protein L14
chr24_-_12745222 1.29 ENSDART00000151836
si:ch211-196f5.9
si:ch211-196f5.9
chr23_+_28648864 1.27 ENSDART00000189096
l1cama
L1 cell adhesion molecule, paralog a
chr21_-_5799122 1.26 ENSDART00000129351
ENSDART00000151202
ccni
cyclin I
chr14_-_24332786 1.26 ENSDART00000173164
fam13b
family with sequence similarity 13, member B
chr1_-_53907092 1.26 ENSDART00000007732
capn9
calpain 9
chr6_-_40697585 1.26 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr7_+_46004893 1.25 ENSDART00000183798
si:ch211-260e23.9
si:ch211-260e23.9
chr14_-_36799280 1.24 ENSDART00000168615
rnf130
ring finger protein 130
chr10_-_4980150 1.24 ENSDART00000093228
mat2al
methionine adenosyltransferase II, alpha-like
chr23_+_24926407 1.24 ENSDART00000137486
klhl21
kelch-like family member 21
chr15_+_14202114 1.24 ENSDART00000169369
si:dkey-243k1.3
si:dkey-243k1.3
chr21_-_131236 1.22 ENSDART00000160005
si:ch1073-398f15.1
si:ch1073-398f15.1
chr9_+_44430705 1.21 ENSDART00000190696
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_+_16536453 1.19 ENSDART00000100287
grk7a
G protein-coupled receptor kinase 7a
chr22_+_20195280 1.18 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
si:dkey-110c1.7
chr7_+_69841017 1.17 ENSDART00000169107
FO818704.1

chr15_-_14552101 1.17 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr13_-_22843562 1.15 ENSDART00000142738
pbld
phenazine biosynthesis like protein domain containing
chr3_+_23092762 1.15 ENSDART00000142884
ENSDART00000024136
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr9_-_43142636 1.15 ENSDART00000134349
ENSDART00000181835
ccdc141
coiled-coil domain containing 141
chr7_-_23745984 1.14 ENSDART00000048050
ITGB1BP2
zgc:92429
chr13_-_50139916 1.14 ENSDART00000099475
nid1a
nidogen 1a
chr20_+_16881883 1.14 ENSDART00000130107
nfkbiaa
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr9_-_23990416 1.14 ENSDART00000113176
col6a3
collagen, type VI, alpha 3
chr6_-_35472923 1.13 ENSDART00000185907
rgs8
regulator of G protein signaling 8
chr3_+_14339728 1.13 ENSDART00000184127
plppr2a
phospholipid phosphatase related 2a
chr23_+_18722915 1.13 ENSDART00000025057
myh7bb
myosin, heavy chain 7B, cardiac muscle, beta b
chr23_-_15284757 1.12 ENSDART00000139135
sulf2b
sulfatase 2b
chr8_+_44420108 1.12 ENSDART00000075381
CU571323.1

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2d

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0003097 renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
1.5 7.6 GO:0003210 cardiac atrium formation(GO:0003210)
1.5 4.5 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
1.3 5.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
1.3 3.8 GO:0097264 self proteolysis(GO:0097264)
1.2 6.0 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.8 3.2 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.8 2.4 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.8 4.0 GO:0097066 response to thyroid hormone(GO:0097066)
0.8 2.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.7 9.1 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.7 5.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.6 1.9 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.6 1.9 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.6 4.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.6 1.7 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.6 4.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.5 2.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.5 4.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.5 1.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.5 1.6 GO:0010265 SCF complex assembly(GO:0010265)
0.5 7.0 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.5 1.4 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.5 2.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.4 4.0 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.4 1.8 GO:0018199 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.4 1.3 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.4 4.0 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.4 3.1 GO:0090594 inflammatory response to wounding(GO:0090594)
0.4 2.0 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.4 1.1 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.4 3.0 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.4 1.8 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.4 4.6 GO:0090303 positive regulation of wound healing(GO:0090303)
0.3 4.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957) regulation of protein activation cascade(GO:2000257)
0.3 2.5 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 0.9 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857)
0.3 2.1 GO:0003207 cardiac chamber formation(GO:0003207)
0.3 1.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 1.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.3 3.6 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.3 1.7 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.3 3.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.3 1.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.3 4.9 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.3 1.5 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.2 2.6 GO:0051597 response to methylmercury(GO:0051597)
0.2 1.5 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.2 1.0 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.2 2.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 1.2 GO:0007603 phototransduction, visible light(GO:0007603)
0.2 1.9 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 2.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.2 0.9 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 2.7 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.2 0.7 GO:0070166 enamel mineralization(GO:0070166)
0.2 1.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 4.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.2 1.6 GO:0060612 adipose tissue development(GO:0060612)
0.2 2.4 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.2 0.8 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.2 7.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.6 GO:0045730 respiratory burst(GO:0045730)
0.1 1.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 4.2 GO:0042476 odontogenesis(GO:0042476)
0.1 2.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 0.8 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 1.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.7 GO:0008584 male gonad development(GO:0008584)
0.1 1.7 GO:0032264 IMP salvage(GO:0032264)
0.1 1.7 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 2.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 1.6 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.3 GO:0014823 response to activity(GO:0014823)
0.1 0.6 GO:0070640 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.1 5.8 GO:0006096 glycolytic process(GO:0006096)
0.1 1.6 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.3 GO:1902893 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 1.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.9 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.1 2.0 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 2.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 3.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.5 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.1 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.8 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 1.1 GO:0035860 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574) positive regulation of vascular endothelial growth factor production(GO:0010575) esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 1.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 2.5 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 1.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.7 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 3.7 GO:0051693 actin filament capping(GO:0051693)
0.1 3.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 7.7 GO:0006936 muscle contraction(GO:0006936)
0.1 0.3 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.1 0.4 GO:0021634 optic nerve formation(GO:0021634)
0.1 1.1 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.5 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.3 GO:0006833 water transport(GO:0006833)
0.1 1.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 2.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.4 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.1 0.4 GO:0031643 positive regulation of myelination(GO:0031643) positive regulation of neurological system process(GO:0031646)
0.1 2.0 GO:0030901 midbrain development(GO:0030901)
0.1 0.5 GO:1901571 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.1 1.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 1.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.8 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.6 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0031641 regulation of myelination(GO:0031641)
0.0 1.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.8 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 3.0 GO:0021549 cerebellum development(GO:0021549)
0.0 0.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 2.6 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.2 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.3 GO:0038026 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 1.3 GO:0007586 digestion(GO:0007586)
0.0 1.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.8 GO:0050821 protein stabilization(GO:0050821)
0.0 2.2 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.0 1.1 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 1.2 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 1.3 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 1.7 GO:0007492 endoderm development(GO:0007492)
0.0 1.4 GO:0001570 vasculogenesis(GO:0001570)
0.0 1.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 2.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.4 GO:0015908 fatty acid transport(GO:0015908)
0.0 1.6 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.4 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.2 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0006188 IMP biosynthetic process(GO:0006188)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.2 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 1.3 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.1 GO:0048675 axon extension(GO:0048675)
0.0 3.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.3 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 1.0 GO:0048469 cell maturation(GO:0048469)
0.0 0.9 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 1.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 2.6 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 16.8 GO:0031430 M band(GO:0031430)
0.7 5.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.7 7.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.7 5.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.6 3.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.5 4.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.5 3.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 2.3 GO:0008091 spectrin(GO:0008091)
0.3 4.0 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 11.8 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.2 1.9 GO:0031672 A band(GO:0031672)
0.2 0.8 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 13.7 GO:0030018 Z disc(GO:0030018)
0.2 0.5 GO:0097541 axonemal basal plate(GO:0097541)
0.1 3.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.3 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.1 1.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.0 GO:0042583 chromaffin granule(GO:0042583)
0.1 4.0 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 3.7 GO:0043204 perikaryon(GO:0043204)
0.1 4.1 GO:0008305 integrin complex(GO:0008305)
0.1 0.6 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.8 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 3.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 2.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 3.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 2.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.2 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 3.3 GO:0005795 Golgi stack(GO:0005795)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.3 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 3.3 GO:0030133 transport vesicle(GO:0030133)
0.0 19.6 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0003796 lysozyme activity(GO:0003796)
1.0 4.0 GO:0071253 connexin binding(GO:0071253)
0.9 4.5 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.9 5.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.8 6.4 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.7 9.1 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.7 5.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.6 6.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.6 1.8 GO:0047690 aspartyltransferase activity(GO:0047690)
0.6 1.8 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.5 7.0 GO:0051117 ATPase binding(GO:0051117)
0.5 4.6 GO:0016936 galactoside binding(GO:0016936)
0.4 1.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.4 1.8 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.4 2.0 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.4 2.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 1.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.3 1.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.3 8.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 1.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.3 0.8 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.3 1.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.0 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.2 9.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 4.9 GO:0001671 ATPase activator activity(GO:0001671)
0.2 1.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.2 1.7 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 2.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 1.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 4.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 1.7 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.2 1.9 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.2 4.5 GO:0005523 tropomyosin binding(GO:0005523)
0.2 2.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 1.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 1.1 GO:0070330 aromatase activity(GO:0070330)
0.2 5.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.5 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.2 1.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 2.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 3.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 2.0 GO:2001069 glycogen binding(GO:2001069)
0.1 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 2.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.7 GO:0043236 laminin binding(GO:0043236)
0.1 2.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.5 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 3.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.2 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.5 GO:0005178 integrin binding(GO:0005178)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 2.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.8 GO:0098882 structural constituent of presynaptic active zone(GO:0098882) structural constituent of synapse(GO:0098918)
0.0 0.3 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.0 3.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.3 GO:0051087 chaperone binding(GO:0051087)
0.0 1.9 GO:0000049 tRNA binding(GO:0000049)
0.0 39.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 1.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 13.0 GO:0051015 actin filament binding(GO:0051015)
0.0 4.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:1903924 estradiol binding(GO:1903924)
0.0 1.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 6.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.7 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.4 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 2.7 GO:0019838 growth factor binding(GO:0019838)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 2.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 3.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 2.2 GO:0008083 growth factor activity(GO:0008083)
0.0 3.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 27.0 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.8 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.1 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 2.8 GO:0003779 actin binding(GO:0003779)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 4.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 2.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 3.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 5.6 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 1.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.7 2.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.5 3.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 2.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 1.6 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.2 1.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 4.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 1.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 1.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 2.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 3.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 3.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 2.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters