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PRJNA195909:zebrafish embryo and larva development

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Results for meis1a+meis1b

Z-value: 1.65

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Transcription factors associated with meis1a+meis1b

Gene Symbol Gene ID Gene Info
meis1a
ENSDARG00000002937 Meis homeobox 1 a
meis1b
ENSDARG00000012078 Meis homeobox 1 b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
meis1bdr11_v1_chr13_-_5568928_5568928-0.723.0e-02Click!
meis1adr11_v1_chr1_+_51496862_51496862-0.235.5e-01Click!

Activity profile of meis1a+meis1b motif

Sorted Z-values of meis1a+meis1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_27855346 2.71 ENSDART00000175159
ENSDART00000192645
buc
bucky ball
chr18_+_1703984 2.37 ENSDART00000114010
slitrk3a
SLIT and NTRK-like family, member 3a
chr19_+_33850705 2.25 ENSDART00000160356
pex1
peroxisomal biogenesis factor 1
chr5_+_55984270 2.15 ENSDART00000047358
ENSDART00000138191
fkbp6
FK506 binding protein 6
chr17_+_47174525 1.85 ENSDART00000156831
CLIP4
si:dkeyp-47f9.4
chr3_+_29082267 1.73 ENSDART00000145615
cacna1i
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr5_-_67661102 1.72 ENSDART00000013605
zbtb20
zinc finger and BTB domain containing 20
chr12_+_46543572 1.69 ENSDART00000167510
hid1b
HID1 domain containing b
chr17_+_13031497 1.67 ENSDART00000115208
fbxo33
F-box protein 33
chr6_+_51713076 1.62 ENSDART00000146281
ripor3
RIPOR family member 3
chr17_-_29771639 1.62 ENSDART00000086201
ush2a
Usher syndrome 2A (autosomal recessive, mild)
chr12_-_33359052 1.57 ENSDART00000135943
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr20_-_38787047 1.53 ENSDART00000152913
ENSDART00000153430
dnajc5ga
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr2_+_7557912 1.53 ENSDART00000160053
ripk2
receptor-interacting serine-threonine kinase 2
chr2_+_15100742 1.49 ENSDART00000027171
f3b
coagulation factor IIIb
chr22_+_35275468 1.49 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr18_+_45862414 1.48 ENSDART00000024615
rnpepl1
arginyl aminopeptidase like 1
chr24_+_10027902 1.47 ENSDART00000175961
ENSDART00000172773
si:ch211-146l10.8
si:ch211-146l10.8
chr17_+_22311413 1.46 ENSDART00000151929
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr2_-_42552666 1.45 ENSDART00000141399
dip2cb
disco-interacting protein 2 homolog Cb
chr22_+_35275206 1.43 ENSDART00000112234
rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr25_-_16552135 1.41 ENSDART00000125836
si:ch211-266k8.4
si:ch211-266k8.4
chr6_-_39199070 1.39 ENSDART00000131793
c1galt1b
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b
chr19_+_24068223 1.39 ENSDART00000141351
ENSDART00000100420
pex11b
peroxisomal biogenesis factor 11 beta
chr24_-_10006158 1.38 ENSDART00000106244
zgc:171750
zgc:171750
chr5_-_18446483 1.37 ENSDART00000180027
si:dkey-215k6.1
si:dkey-215k6.1
chr12_+_4220353 1.36 ENSDART00000133675
mapk7
mitogen-activated protein kinase 7
chr7_-_11638126 1.35 ENSDART00000125827
si:dkey-15b23.3
si:dkey-15b23.3
chr15_+_14378829 1.35 ENSDART00000160145
si:ch211-11n16.2
si:ch211-11n16.2
chr25_+_5604512 1.34 ENSDART00000042781
plxnb2b
plexin b2b
chr23_-_27505825 1.34 ENSDART00000137229
ENSDART00000013797
asb8
ankyrin repeat and SOCS box containing 8
chr5_-_3991655 1.33 ENSDART00000159368
myo19
myosin XIX
chr25_-_7918526 1.31 ENSDART00000104686
ENSDART00000156761
ambra1b
autophagy/beclin-1 regulator 1b
chr24_-_10014512 1.30 ENSDART00000124341
ENSDART00000191630
zgc:171474
zgc:171474
chr10_-_45029041 1.28 ENSDART00000167878
polm
polymerase (DNA directed), mu
chr8_+_25959940 1.26 ENSDART00000143011
ENSDART00000140626
si:dkey-72l14.4
si:dkey-72l14.4
chr5_+_3891485 1.26 ENSDART00000129329
ENSDART00000091711
rpain
RPA interacting protein
chr6_+_58280936 1.24 ENSDART00000155244
ralgapb
Ral GTPase activating protein, beta subunit (non-catalytic)
chr25_+_19670273 1.21 ENSDART00000073472
zgc:113426
zgc:113426
chr5_+_51248784 1.20 ENSDART00000159571
ENSDART00000189513
ENSDART00000092285
msh3
mutS homolog 3 (E. coli)
chr13_-_32726178 1.20 ENSDART00000012232
pdss2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr24_-_9985019 1.18 ENSDART00000193536
ENSDART00000189595
zgc:171977
zgc:171977
chr17_-_43594864 1.18 ENSDART00000139980
zfyve28
zinc finger, FYVE domain containing 28
chr7_-_19369002 1.17 ENSDART00000165680
ntn4
netrin 4
chr3_-_48612078 1.16 ENSDART00000169923
ndel1b
nudE neurodevelopment protein 1-like 1b
chr21_+_5960443 1.16 ENSDART00000149689
mob1bb
MOB kinase activator 1Bb
chr4_-_20235904 1.13 ENSDART00000146621
ENSDART00000193655
stk38l
serine/threonine kinase 38 like
chr17_-_21049260 1.12 ENSDART00000155300
ENSDART00000185758
bicc1a
BicC family RNA binding protein 1a
chr11_-_9948487 1.12 ENSDART00000189677
ENSDART00000113171
nlgn1
neuroligin 1
chr9_+_38168012 1.11 ENSDART00000102445
clasp1a
cytoplasmic linker associated protein 1a
chr17_+_24809221 1.11 ENSDART00000082251
ENSDART00000147871
ENSDART00000130871
spdya
speedy/RINGO cell cycle regulator family member A
chr24_-_9979342 1.11 ENSDART00000138576
ENSDART00000191206
zgc:171977
zgc:171977
chr17_-_43533095 1.10 ENSDART00000125162
si:dkey-21a6.5
si:dkey-21a6.5
chr5_+_31480342 1.09 ENSDART00000098197
si:dkey-220k22.1
si:dkey-220k22.1
chr12_-_4249000 1.09 ENSDART00000059298
zgc:92313
zgc:92313
chr1_+_27977297 1.09 ENSDART00000180692
ENSDART00000166819
sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr8_-_41519234 1.08 ENSDART00000167283
ENSDART00000180666
golga1
golgin A1
chr11_-_42230491 1.08 ENSDART00000164423
CABZ01030862.1

chr4_-_77561679 1.07 ENSDART00000180809
AL935186.9

chr20_-_26391958 1.06 ENSDART00000078062
armt1
acidic residue methyltransferase 1
chr16_-_18960333 1.05 ENSDART00000143185
fhod3b
formin homology 2 domain containing 3b
chr23_+_40410644 1.03 ENSDART00000056328
elovl4b
ELOVL fatty acid elongase 4b
chr6_-_43387920 1.03 ENSDART00000154434
frmd4ba
FERM domain containing 4Ba
chr13_-_48161568 1.02 ENSDART00000109469
ENSDART00000188052
ENSDART00000193446
ENSDART00000189509
ENSDART00000184810
golga4
golgin A4
chr24_+_10039165 1.02 ENSDART00000144186
pou6f2
POU class 6 homeobox 2
chr14_+_30340251 1.02 ENSDART00000148448
mtus1a
microtubule associated tumor suppressor 1a
chr16_-_18960613 1.00 ENSDART00000183197
fhod3b
formin homology 2 domain containing 3b
chr11_+_31680513 1.00 ENSDART00000139900
ENSDART00000040305
diaph3
diaphanous-related formin 3
chr15_-_4415917 0.99 ENSDART00000062874
atp1b3b
ATPase Na+/K+ transporting subunit beta 3b
chr8_-_41519064 0.98 ENSDART00000098578
ENSDART00000112214
golga1
golgin A1
chr11_+_44804685 0.98 ENSDART00000163660
strn
striatin, calmodulin binding protein
chr1_-_11878845 0.97 ENSDART00000163971
ENSDART00000123431
iqce
IQ motif containing E
chr7_-_11677237 0.97 ENSDART00000164236
si:dkey-15b23.3
si:dkey-15b23.3
chr20_+_35208020 0.97 ENSDART00000153315
ENSDART00000045135
fbxo16
F-box protein 16
chr16_+_26612401 0.96 ENSDART00000145571
epb41l4b
erythrocyte membrane protein band 4.1 like 4B
chr1_+_35473397 0.96 ENSDART00000158799
usp38
ubiquitin specific peptidase 38
chr22_-_24791505 0.96 ENSDART00000136837
vtg4
vitellogenin 4
chr20_-_49961997 0.94 ENSDART00000187569
extl3
exostosin-like glycosyltransferase 3
chr21_+_43178831 0.92 ENSDART00000151512
aff4
AF4/FMR2 family, member 4
chr6_-_7052408 0.92 ENSDART00000150033
ENSDART00000149232
bin1b
bridging integrator 1b
chr17_+_21818093 0.91 ENSDART00000125335
ikzf5
IKAROS family zinc finger 5
chr7_-_69184420 0.91 ENSDART00000168311
ENSDART00000159239
ENSDART00000161319
usp10
ubiquitin specific peptidase 10
chr11_-_20987378 0.91 ENSDART00000110140
taf4a
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr8_-_19451487 0.91 ENSDART00000184037
zgc:92140
zgc:92140
chr16_+_11297703 0.90 ENSDART00000125158
znf574
zinc finger protein 574
chr8_+_14959587 0.90 ENSDART00000138548
ENSDART00000041697
abl2
c-abl oncogene 2, non-receptor tyrosine kinase
chr19_-_31686252 0.90 ENSDART00000131721
ripor2
RHO family interacting cell polarization regulator 2
chr16_-_13612650 0.89 ENSDART00000080372
dbpb
D site albumin promoter binding protein b
chr16_-_17577581 0.89 ENSDART00000186475
ENSDART00000137215
casp2
caspase 2, apoptosis-related cysteine peptidase
chr17_+_23556764 0.89 ENSDART00000146787
pank1a
pantothenate kinase 1a
chr8_+_25173317 0.89 ENSDART00000142006
gpr61
G protein-coupled receptor 61
chr6_-_7052595 0.88 ENSDART00000081761
ENSDART00000181351
bin1b
bridging integrator 1b
chr21_+_22330005 0.88 ENSDART00000140751
ENSDART00000157839
ENSDART00000140468
nadk2
NAD kinase 2, mitochondrial
chr22_-_38035084 0.88 ENSDART00000145029
pex6
peroxisomal biogenesis factor 6
chr4_+_16768961 0.87 ENSDART00000143926
BX649500.1

chr10_-_11840353 0.87 ENSDART00000127581
trim23
tripartite motif containing 23
chr18_-_16315822 0.86 ENSDART00000136479
rassf9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr8_+_8238727 0.86 ENSDART00000144838
plxnb3
plexin B3
chr18_+_5510251 0.85 ENSDART00000007797
slc30a4
solute carrier family 30 (zinc transporter), member 4
chr16_-_8132742 0.85 ENSDART00000104323
snrka
SNF related kinase a
chr16_-_30826712 0.85 ENSDART00000122474
ptk2ab
protein tyrosine kinase 2ab
chr10_+_43117661 0.85 ENSDART00000024644
ENSDART00000186932
xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr4_-_14191434 0.85 ENSDART00000142374
ENSDART00000136730
pus7l
pseudouridylate synthase 7-like
chr7_-_18881358 0.84 ENSDART00000021502
mllt3
MLLT3, super elongation complex subunit
chr9_-_25366541 0.83 ENSDART00000021672
epc2
enhancer of polycomb homolog 2 (Drosophila)
chr10_+_39476600 0.83 ENSDART00000135756
kirrel3a
kirre like nephrin family adhesion molecule 3a
chr4_-_14192254 0.83 ENSDART00000143804
pus7l
pseudouridylate synthase 7-like
chr7_-_17814118 0.82 ENSDART00000179688
ecsit
ECSIT signalling integrator
chr16_-_13613475 0.81 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr8_+_52284075 0.81 ENSDART00000098439
ube2d4
ubiquitin-conjugating enzyme E2D 4 (putative)
chr8_-_34427364 0.79 ENSDART00000112854
ENSDART00000161282
ENSDART00000113230
gapvd1
GTPase activating protein and VPS9 domains 1
chr7_-_13884610 0.79 ENSDART00000006897
rlbp1a
retinaldehyde binding protein 1a
chr21_-_22435957 0.78 ENSDART00000137959
il7r
interleukin 7 receptor
chr4_-_14191717 0.78 ENSDART00000147928
pus7l
pseudouridylate synthase 7-like
chr7_+_16352924 0.77 ENSDART00000158972
mpped2a
metallophosphoesterase domain containing 2a
chr7_-_23848012 0.76 ENSDART00000146104
ENSDART00000175108
si:ch211-200p22.4
si:ch211-200p22.4
chr5_+_56119975 0.76 ENSDART00000083137
mrm1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr6_+_21227621 0.76 ENSDART00000193583
prkca
protein kinase C, alpha
chr23_-_19682971 0.74 ENSDART00000048891
zgc:193598
zgc:193598
chr11_-_36957127 0.74 ENSDART00000168528
cacna1da
calcium channel, voltage-dependent, L type, alpha 1D subunit, a
chr10_-_45210184 0.74 ENSDART00000167128
pargl
poly (ADP-ribose) glycohydrolase, like
chr6_+_49021703 0.74 ENSDART00000149394
slc16a1a
solute carrier family 16 (monocarboxylate transporter), member 1a
chr20_-_7176809 0.74 ENSDART00000012247
ENSDART00000125019
dhcr24
24-dehydrocholesterol reductase
chr20_+_3339248 0.74 ENSDART00000108955
mfsd4b
major facilitator superfamily domain containing 4B
chr22_-_38034852 0.74 ENSDART00000104613
pex6
peroxisomal biogenesis factor 6
chr19_+_7636941 0.74 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr16_+_37891735 0.73 ENSDART00000178753
ENSDART00000142104
cep162
centrosomal protein 162
chr15_+_31590224 0.72 ENSDART00000159634
b3glcta
beta 3-glucosyltransferase a
chr15_-_9294929 0.72 ENSDART00000155717
si:ch211-261a10.5
si:ch211-261a10.5
chr2_-_27855576 0.72 ENSDART00000121623
FO834800.1

chr11_+_31121340 0.72 ENSDART00000185172
stx10
syntaxin 10
chr13_+_42762226 0.72 ENSDART00000135231
cdh23
cadherin-related 23
chr2_-_8609653 0.72 ENSDART00000193354
ENSDART00000189489
ENSDART00000186144
si:ch211-71m22.1
si:ch211-71m22.1
chr2_+_51645164 0.71 ENSDART00000169600
abhd4
abhydrolase domain containing 4
chr11_+_43751263 0.71 ENSDART00000163843
zgc:153431
zgc:153431
chr12_-_17593030 0.70 ENSDART00000168758
usp42
ubiquitin specific peptidase 42
chr12_+_34273240 0.70 ENSDART00000037904
socs3b
suppressor of cytokine signaling 3b
chr24_-_20320480 0.69 ENSDART00000137366
map3k20
mitogen-activated protein kinase kinase kinase 20
chr12_-_31461219 0.69 ENSDART00000148954
acsl5
acyl-CoA synthetase long chain family member 5
chr7_-_55292116 0.69 ENSDART00000122603
rnf166
ring finger protein 166
chr22_+_1006573 0.69 ENSDART00000123458
pparda
peroxisome proliferator-activated receptor delta a
chr13_-_33227411 0.69 ENSDART00000057386
golga5
golgin A5
chr11_-_34480822 0.69 ENSDART00000129029
xxylt1
xyloside xylosyltransferase 1
chr5_-_13086616 0.68 ENSDART00000051664
ypel1
yippee-like 1
chr10_+_29770120 0.68 ENSDART00000100032
ENSDART00000193205
hyou1
hypoxia up-regulated 1
chr9_+_29643036 0.68 ENSDART00000023210
ENSDART00000175160
trim13
tripartite motif containing 13
chr8_+_19621731 0.67 ENSDART00000144667
slc35a3a
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr20_-_36575475 0.66 ENSDART00000062893
enah
enabled homolog (Drosophila)
chr13_-_27621246 0.66 ENSDART00000102232
kcnq5a
potassium voltage-gated channel, KQT-like subfamily, member 5a
chr21_-_16399778 0.66 ENSDART00000136435
unc5da
unc-5 netrin receptor Da
chr7_-_19526721 0.66 ENSDART00000114203
man2b2
mannosidase, alpha, class 2B, member 2
chr15_+_28116129 0.66 ENSDART00000185157
unc119a
unc-119 homolog a (C. elegans)
chr22_+_26703026 0.66 ENSDART00000158756
crebbpa
CREB binding protein a
chr8_-_17771755 0.66 ENSDART00000063592
prkcz
protein kinase C, zeta
chr1_-_59216197 0.66 ENSDART00000062426
lpar2b
lysophosphatidic acid receptor 2b
chr21_+_37357578 0.65 ENSDART00000143621
nsd1b
nuclear receptor binding SET domain protein 1b
chr5_+_26805608 0.65 ENSDART00000111019
rabl6b
RAB, member RAS oncogene family-like 6b
chr10_-_25328814 0.64 ENSDART00000123820
tmem135
transmembrane protein 135
chr21_-_20945658 0.64 ENSDART00000079701
rnf180
ring finger protein 180
chr11_+_41540862 0.64 ENSDART00000173210
kcnab2a
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr8_-_31384607 0.64 ENSDART00000164134
ENSDART00000024872
creb3l3l
cAMP responsive element binding protein 3-like 3 like
chr14_+_9485070 0.64 ENSDART00000161486
ENSDART00000137274
st3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr23_+_23182037 0.64 ENSDART00000137353
klhl17
kelch-like family member 17
chr8_+_19621511 0.64 ENSDART00000017128
slc35a3a
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr12_+_1286642 0.63 ENSDART00000157467
pemt
phosphatidylethanolamine N-methyltransferase
chr8_+_7801060 0.62 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr3_+_29600917 0.62 ENSDART00000048867
sstr3
somatostatin receptor 3
chr3_+_32715088 0.62 ENSDART00000125022
setd1a
SET domain containing 1A
chr12_-_35582683 0.62 ENSDART00000167933
sec24c
SEC24 homolog C, COPII coat complex component
chr12_+_2993523 0.62 ENSDART00000082297
lrrc45
leucine rich repeat containing 45
chr13_-_34858500 0.62 ENSDART00000184843
sptlc3
serine palmitoyltransferase, long chain base subunit 3
chr3_-_31833266 0.62 ENSDART00000084932
ENSDART00000183617
map3k3
mitogen-activated protein kinase kinase kinase 3
chr4_-_17353972 0.61 ENSDART00000041529
parpbp
PARP1 binding protein
chr18_-_41160579 0.61 ENSDART00000181480
CABZ01005876.1

chr6_-_24203980 0.61 ENSDART00000170915
si:ch73-389b16.2
si:ch73-389b16.2
chr19_-_34742440 0.61 ENSDART00000122625
ENSDART00000175621
elp2
elongator acetyltransferase complex subunit 2
chr5_-_14521500 0.61 ENSDART00000176565
si:ch211-244o22.2
si:ch211-244o22.2
chr3_+_17634952 0.61 ENSDART00000191833
rab5c
RAB5C, member RAS oncogene family
chr17_-_7792376 0.60 ENSDART00000064655
zbtb2a
zinc finger and BTB domain containing 2a
chr20_+_38910214 0.60 ENSDART00000047362
msra
methionine sulfoxide reductase A
chr5_-_32813933 0.60 ENSDART00000050041
ENSDART00000135864
ptpa
protein phosphatase 2 phosphatase activator
chr1_+_32341734 0.60 ENSDART00000135078
pudp
pseudouridine 5'-phosphatase
chr7_+_6915609 0.59 ENSDART00000159213
ccs
copper chaperone for superoxide dismutase
chr2_-_11027258 0.59 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
ssbp3a
single stranded DNA binding protein 3a
chr22_+_17214389 0.59 ENSDART00000187083
ENSDART00000159468
ENSDART00000129109
ENSDART00000090107
nrd1b
nardilysin b (N-arginine dibasic convertase)
chr11_-_544187 0.58 ENSDART00000173161
CU695207.1

chr17_+_34186632 0.58 ENSDART00000014306
mpp5a
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr10_+_26961965 0.57 ENSDART00000089144
vps51
vacuolar protein sorting 51 homolog (S. cerevisiae)
chr12_-_22509069 0.57 ENSDART00000179755
ENSDART00000109707
neurl4
neuralized E3 ubiquitin protein ligase 4
chr12_-_26538823 0.57 ENSDART00000143213
acsf2
acyl-CoA synthetase family member 2
chr24_+_39656834 0.57 ENSDART00000133942
ENSDART00000148089
ENSDART00000145075
stub1
STIP1 homology and U-Box containing protein 1
chr6_+_54154807 0.57 ENSDART00000061735
nudt3b
nudix (nucleoside diphosphate linked moiety X)-type motif 3b
chr4_-_21466825 0.57 ENSDART00000066897
pawr
PRKC, apoptosis, WT1, regulator
chr1_-_12397258 0.56 ENSDART00000144596
sclt1
sodium channel and clathrin linker 1
chr3_+_19687217 0.56 ENSDART00000141937
tlk2
tousled-like kinase 2
chr20_-_37813863 0.56 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr19_-_9503473 0.56 ENSDART00000091615
iffo1a
intermediate filament family orphan 1a
chr2_-_33676494 0.56 ENSDART00000141192
b4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr12_-_35582521 0.56 ENSDART00000162175
ENSDART00000168958
sec24c
SEC24 homolog C, COPII coat complex component
chr9_+_23770666 0.55 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3

Network of associatons between targets according to the STRING database.

First level regulatory network of meis1a+meis1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.5 2.7 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.4 1.2 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.3 0.9 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.2 1.4 GO:0016559 peroxisome fission(GO:0016559)
0.2 0.7 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.2 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 4.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 0.9 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.2 1.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 1.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 0.9 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.2 0.8 GO:0033152 DNA ligation(GO:0006266) immunoglobulin V(D)J recombination(GO:0033152) DNA ligation involved in DNA repair(GO:0051103)
0.2 0.5 GO:1901052 sarcosine metabolic process(GO:1901052)
0.2 0.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.2 0.6 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.6 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.7 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.6 GO:1901908 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 2.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.5 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 1.1 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.1 1.0 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 0.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.3 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 2.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.6 GO:0044241 lipid digestion(GO:0044241)
0.1 0.6 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 2.1 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.8 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.4 GO:0010939 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.1 1.3 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.5 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.7 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.6 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 1.6 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 1.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.8 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 0.7 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.4 GO:1903010 regulation of bone development(GO:1903010)
0.1 1.3 GO:0032418 lysosome localization(GO:0032418)
0.1 1.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.1 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.5 GO:0048069 eye pigmentation(GO:0048069)
0.1 1.5 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.7 GO:0000305 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.4 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.1 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.6 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.0 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.2 GO:0060765 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.1 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.5 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.6 GO:0098900 regulation of action potential(GO:0098900)
0.1 1.2 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.4 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.0 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788)
0.1 1.0 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.7 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 0.3 GO:0090148 membrane fission(GO:0090148)
0.1 1.3 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 0.5 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.6 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.6 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.4 GO:0009146 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.0 1.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.8 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 1.1 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.3 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.9 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.0 0.9 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 1.2 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.8 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.7 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.0 0.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.3 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0051204 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 1.2 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 1.0 GO:0032355 response to estradiol(GO:0032355)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 1.1 GO:0050821 protein stabilization(GO:0050821)
0.0 0.6 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 1.1 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.6 GO:0060021 palate development(GO:0060021)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700) regulation of lymphangiogenesis(GO:1901490)
0.0 2.3 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.5 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.4 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.6 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 1.3 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.7 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.2 GO:0015809 arginine transport(GO:0015809)
0.0 0.5 GO:0000959 mitochondrial RNA metabolic process(GO:0000959)
0.0 3.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0035264 multicellular organism growth(GO:0035264)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 1.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.1 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 1.3 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
0.0 0.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.5 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.4 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)
0.0 2.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 2.9 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.1 GO:0007596 blood coagulation(GO:0007596)
0.0 0.9 GO:0051028 mRNA transport(GO:0051028)
0.0 0.7 GO:0097696 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 0.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.5 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.0 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.3 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.8 GO:0007416 synapse assembly(GO:0007416)
0.0 0.6 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.0 GO:0036316 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.4 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.3 GO:0021986 habenula development(GO:0021986)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.3 2.7 GO:0032019 mitochondrial cloud(GO:0032019)
0.3 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 0.8 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.3 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 1.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 0.9 GO:0060171 stereocilium membrane(GO:0060171)
0.2 0.6 GO:1990745 EARP complex(GO:1990745)
0.2 0.5 GO:0042721 mitochondrial intermembrane space protein transporter complex(GO:0042719) mitochondrial inner membrane protein insertion complex(GO:0042721)
0.2 1.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.7 GO:0005879 axonemal microtubule(GO:0005879)
0.1 1.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.2 GO:0032300 mismatch repair complex(GO:0032300)
0.1 4.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.5 GO:0033263 CORVET complex(GO:0033263)
0.1 1.0 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 1.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.8 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.4 GO:0016589 NURF complex(GO:0016589)
0.1 0.6 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.4 GO:0000796 condensin complex(GO:0000796)
0.1 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 1.2 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0032797 SMN complex(GO:0032797)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 5.8 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.3 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.4 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.5 GO:0031082 BLOC complex(GO:0031082)
0.0 2.1 GO:0042383 sarcolemma(GO:0042383)
0.0 3.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.3 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 1.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0043195 terminal bouton(GO:0043195)
0.0 1.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.1 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.9 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.1 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.3 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 1.0 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0032135 DNA insertion or deletion binding(GO:0032135)
0.3 1.8 GO:0048156 tau protein binding(GO:0048156)
0.2 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 0.6 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.2 1.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 2.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 0.6 GO:0047760 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.2 0.7 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.2 1.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.6 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.1 1.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.0 GO:0045735 nutrient reservoir activity(GO:0045735)
0.1 1.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 2.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.5 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 1.1 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.6 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.7 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 0.3 GO:0042806 fucose binding(GO:0042806)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.6 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 2.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.6 GO:0031267 small GTPase binding(GO:0031267)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0016793 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.1 0.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.9 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 2.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 1.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.9 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0045309 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 1.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.0 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 4.4 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.7 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 1.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 2.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.8 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.7 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 1.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.2 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 3.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.5 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.8 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 2.0 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 0.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 2.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.9 ST GA12 PATHWAY G alpha 12 Pathway
0.1 2.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 1.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 0.9 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID IGF1 PATHWAY IGF1 pathway
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 1.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.0 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.5 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 2.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon