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PRJNA195909:zebrafish embryo and larva development

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Results for meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

Z-value: 1.94

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Transcription factors associated with meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

Gene Symbol Gene ID Gene Info
meis2b
ENSDARG00000077840 Meis homeobox 2a
meis2a
ENSDARG00000098240 Meis homeobox 2a
FO834857.1
ENSDARG00000112895 homeobox protein TGIF2-like
pknox1.1
ENSDARG00000018765 pbx/knotted 1 homeobox 1.1
pknox1.2
ENSDARG00000036542 pbx/knotted 1 homeobox 1.2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
meis2bdr11_v1_chr20_-_10120442_10120442-0.901.1e-03Click!
FO834857.1dr11_v1_chr6_-_1814457_18144570.854.0e-03Click!
meis2adr11_v1_chr17_+_52822831_52822831-0.599.7e-02Click!
pknox1.1dr11_v1_chr9_+_19529951_195299510.531.4e-01Click!
pknox1.2dr11_v1_chr1_-_46984142_46984142-0.333.9e-01Click!

Activity profile of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2 motif

Sorted Z-values of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_25959940 3.72 ENSDART00000143011
ENSDART00000140626
si:dkey-72l14.4
si:dkey-72l14.4
chr17_-_36860988 3.29 ENSDART00000154981
senp6b
SUMO1/sentrin specific peptidase 6b
chr8_-_32385989 3.08 ENSDART00000143716
ENSDART00000098850
lipg
lipase, endothelial
chr14_-_41468892 2.96 ENSDART00000173099
ENSDART00000003170
mid1ip1l
MID1 interacting protein 1, like
chr12_-_48168135 2.77 ENSDART00000186624
pald1a
phosphatase domain containing, paladin 1a
chr14_-_6402769 2.77 ENSDART00000121552
slc44a1b
solute carrier family 44 (choline transporter), member 1b
chr6_+_49052741 2.66 ENSDART00000011876
sycp1
synaptonemal complex protein 1
chr22_-_37834312 2.56 ENSDART00000076128
ppp1r2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr3_+_7771420 2.55 ENSDART00000156809
ENSDART00000156309
hook2
hook microtubule-tethering protein 2
chr16_+_50434668 2.53 ENSDART00000193500
IGLON5
zgc:110372
chr23_-_18024543 2.52 ENSDART00000139695
pm20d1.1
peptidase M20 domain containing 1, tandem duplicate 1
chr12_+_18916285 2.49 ENSDART00000127536
cbx7b
chromobox homolog 7b
chr17_-_7792376 2.49 ENSDART00000064655
zbtb2a
zinc finger and BTB domain containing 2a
chr2_-_11027258 2.40 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
ssbp3a
single stranded DNA binding protein 3a
chr20_-_28433990 2.38 ENSDART00000182824
ENSDART00000193381
wdr21
WD repeat domain 21
chr10_+_37500234 2.36 ENSDART00000132096
ENSDART00000099473
msi2a
musashi RNA-binding protein 2a
chr9_+_27876146 2.35 ENSDART00000133997
armc8
armadillo repeat containing 8
chr23_+_39963599 2.33 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr18_+_35128685 2.31 ENSDART00000151579
si:ch211-195m9.3
si:ch211-195m9.3
chr23_-_31060350 2.30 ENSDART00000145598
ENSDART00000191491
si:ch211-197l9.5
si:ch211-197l9.5
chr11_+_44503774 2.29 ENSDART00000169295
ero1b
endoplasmic reticulum oxidoreductase beta
chr19_-_6134802 2.28 ENSDART00000140051
cica
capicua transcriptional repressor a
chr11_+_5880562 2.26 ENSDART00000129663
ENSDART00000130768
ENSDART00000160909
dazap1
DAZ associated protein 1
chr4_+_27898833 2.25 ENSDART00000146099
cerk
ceramide kinase
chr16_-_51072406 2.17 ENSDART00000083777
ago3a
argonaute RISC catalytic component 3a
chr13_+_46803979 2.15 ENSDART00000159260
CU695232.1

chr5_+_27137473 2.15 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr4_-_20081621 2.11 ENSDART00000024647
dennd6b
DENN/MADD domain containing 6B
chr2_-_38117538 2.05 ENSDART00000013676
chd8
chromodomain helicase DNA binding protein 8
chr23_-_36592436 2.05 ENSDART00000168246
spryd3
SPRY domain containing 3
chr13_+_45524475 2.03 ENSDART00000074567
ENSDART00000019113
maco1b
macoilin 1b
chr6_-_57539141 2.02 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr1_+_24382651 2.00 ENSDART00000123789
qdprb2
quinoid dihydropteridine reductase b2
chr5_-_41124241 1.95 ENSDART00000083561
mtmr12
myotubularin related protein 12
chr14_+_29200772 1.95 ENSDART00000166608
TENM2
si:dkey-34l15.2
chr21_-_25612658 1.94 ENSDART00000115276
fibpb
fibroblast growth factor (acidic) intracellular binding protein b
chr13_+_23104134 1.94 ENSDART00000110266
pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr6_-_41135215 1.93 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr8_-_41519234 1.92 ENSDART00000167283
ENSDART00000180666
golga1
golgin A1
chr5_-_69482891 1.91 ENSDART00000109487
CABZ01032476.1

chr22_-_16377960 1.90 ENSDART00000168170
ttc39c
tetratricopeptide repeat domain 39C
chr14_-_34605607 1.90 ENSDART00000191608
afap1l1a
actin filament associated protein 1-like 1a
chr19_+_42231431 1.87 ENSDART00000102698
jtb
jumping translocation breakpoint
chr15_-_28587147 1.86 ENSDART00000156049
ssh2a
slingshot protein phosphatase 2a
chr13_-_24396003 1.84 ENSDART00000016211
tbp
TATA box binding protein
chr11_-_34478225 1.83 ENSDART00000189604
xxylt1
xyloside xylosyltransferase 1
chr7_+_16352924 1.82 ENSDART00000158972
mpped2a
metallophosphoesterase domain containing 2a
chr25_-_1323623 1.80 ENSDART00000156532
ENSDART00000157163
ENSDART00000156062
ENSDART00000082447
ENSDART00000189175
calml4b
calmodulin-like 4b
chr15_+_23528310 1.79 ENSDART00000152523
si:dkey-182i3.8
si:dkey-182i3.8
chr22_-_16377666 1.78 ENSDART00000161878
ttc39c
tetratricopeptide repeat domain 39C
chr8_-_41519064 1.78 ENSDART00000098578
ENSDART00000112214
golga1
golgin A1
chr19_-_46032556 1.77 ENSDART00000167185
nup153
nucleoporin 153
chr14_+_30340251 1.77 ENSDART00000148448
mtus1a
microtubule associated tumor suppressor 1a
chr14_-_34605804 1.76 ENSDART00000144547
afap1l1a
actin filament associated protein 1-like 1a
chr15_-_506010 1.69 ENSDART00000155472
nudt8
nudix (nucleoside diphosphate linked moiety X)-type motif 8
chr15_-_28587490 1.68 ENSDART00000186196
ssh2a
slingshot protein phosphatase 2a
chr8_-_410728 1.67 ENSDART00000151255
trim36
tripartite motif containing 36
chr10_-_35177257 1.66 ENSDART00000077426
pom121
POM121 transmembrane nucleoporin
chr20_+_1329509 1.64 ENSDART00000017791
ENSDART00000136669
tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr17_+_33999630 1.63 ENSDART00000167085
ENSDART00000155030
ENSDART00000168522
ENSDART00000191799
ENSDART00000189684
ENSDART00000153942
ENSDART00000187272
ENSDART00000127692
gphna
gephyrin a
chr5_-_13766651 1.62 ENSDART00000134064
mxd1
MAX dimerization protein 1
chr7_-_37555208 1.61 ENSDART00000148905
ENSDART00000150229
cylda
cylindromatosis (turban tumor syndrome), a
chr15_+_23528010 1.61 ENSDART00000152786
si:dkey-182i3.8
si:dkey-182i3.8
chr19_+_43905671 1.60 ENSDART00000168725
ENSDART00000133628
ankib1a
ankyrin repeat and IBR domain containing 1a
chr21_+_39336285 1.58 ENSDART00000139677
si:ch211-274p24.4
si:ch211-274p24.4
chr23_+_13528053 1.57 ENSDART00000162217
uckl1b
uridine-cytidine kinase 1-like 1b
chr12_-_33659328 1.57 ENSDART00000153457
tmem94
transmembrane protein 94
chr24_-_41180149 1.56 ENSDART00000019975
acvr2ba
activin A receptor type 2Ba
chr6_-_10809546 1.55 ENSDART00000151661
wipf1b
WAS/WASL interacting protein family, member 1b
chr13_-_24396199 1.54 ENSDART00000181093
tbp
TATA box binding protein
chr9_-_12575776 1.53 ENSDART00000128931
ENSDART00000182695
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr20_+_3339248 1.52 ENSDART00000108955
mfsd4b
major facilitator superfamily domain containing 4B
chr25_+_14870043 1.52 ENSDART00000035714
ENSDART00000171835
dnajc24
DnaJ (Hsp40) homolog, subfamily C, member 24
chr18_+_39487486 1.52 ENSDART00000126978
acadl
acyl-CoA dehydrogenase long chain
chr17_+_19630068 1.47 ENSDART00000182619
rgs7a
regulator of G protein signaling 7a
chr3_+_29082267 1.46 ENSDART00000145615
cacna1i
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr18_+_907266 1.44 ENSDART00000171729
pkma
pyruvate kinase M1/2a
chr1_+_45217425 1.44 ENSDART00000179983
ENSDART00000074683
EVI5L
si:ch211-239f4.1
chr5_-_18474486 1.44 ENSDART00000090580
si:dkey-215k6.1
si:dkey-215k6.1
chr7_+_52761841 1.41 ENSDART00000111444
ppip5k1a
diphosphoinositol pentakisphosphate kinase 1a
chr24_-_36095526 1.41 ENSDART00000158145
CABZ01075509.1

chr9_-_52490579 1.40 ENSDART00000161667
smarcal1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr21_-_14832369 1.39 ENSDART00000144859
pus1
pseudouridylate synthase 1
chr2_+_30489846 1.38 ENSDART00000145732
march6
membrane-associated ring finger (C3HC4) 6
chr8_+_44623540 1.38 ENSDART00000141513
grk5l
G protein-coupled receptor kinase 5 like
chr7_-_9873652 1.38 ENSDART00000006343
asb7
ankyrin repeat and SOCS box containing 7
chr17_+_50074372 1.36 ENSDART00000113644
vps39
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr1_+_45217619 1.36 ENSDART00000125037
EVI5L
si:ch211-239f4.1
chr2_-_45510699 1.35 ENSDART00000024034
ENSDART00000145634
gpsm2
G protein signaling modulator 2
chr17_-_50040927 1.35 ENSDART00000184304
FO834825.1

chr5_-_35200590 1.34 ENSDART00000051271
fcho2
FCH domain only 2
chr6_+_38773376 1.33 ENSDART00000078128
ENSDART00000184053
ube3a
ubiquitin protein ligase E3A
chr13_-_7233811 1.32 ENSDART00000162026
ninl
ninein-like
chr23_+_21492151 1.31 ENSDART00000025487
icmt
isoprenylcysteine carboxyl methyltransferase
chr5_-_39805620 1.30 ENSDART00000137801
rasgef1ba
RasGEF domain family, member 1Ba
chr4_-_73394385 1.30 ENSDART00000174205
ENSDART00000143417
zgc:162958
zgc:162958
chr2_+_27855346 1.29 ENSDART00000175159
ENSDART00000192645
buc
bucky ball
chr25_-_3192405 1.29 ENSDART00000104835
hps5
Hermansky-Pudlak syndrome 5
chr7_-_56766100 1.29 ENSDART00000189934
csnk2a2a
casein kinase 2, alpha prime polypeptide a
chr21_-_13123176 1.25 ENSDART00000144866
ENSDART00000024616
fam219aa
family with sequence similarity 219, member Aa
chr9_+_33267211 1.24 ENSDART00000025635
usp9
ubiquitin specific peptidase 9
chr9_-_12575569 1.24 ENSDART00000102419
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr25_+_22319940 1.24 ENSDART00000154065
ENSDART00000153492
ENSDART00000024866
ENSDART00000154376
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr20_-_20270191 1.24 ENSDART00000009356
ppp2r5ea
protein phosphatase 2, regulatory subunit B', epsilon isoform a
chr10_+_28160265 1.23 ENSDART00000022484
rnft1
ring finger protein, transmembrane 1
chr5_-_23485161 1.23 ENSDART00000170293
ENSDART00000134069
si:dkeyp-20g2.1
si:dkeyp-20g2.3
si:dkeyp-20g2.1
si:dkeyp-20g2.3
chr14_-_21238046 1.23 ENSDART00000129743
si:ch211-175m2.5
si:ch211-175m2.5
chr14_-_33481428 1.23 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr22_+_1006573 1.23 ENSDART00000123458
pparda
peroxisome proliferator-activated receptor delta a
chr3_+_17030665 1.22 ENSDART00000159849
ENSDART00000174491
ENSDART00000104519
ENSDART00000080854
stat3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr20_-_28433616 1.22 ENSDART00000169289
wdr21
WD repeat domain 21
chr5_-_23675222 1.22 ENSDART00000135153
TBC1D8B
si:dkey-110k5.6
chr14_+_23184517 1.21 ENSDART00000181410
enox2
ecto-NOX disulfide-thiol exchanger 2
chr12_-_48467733 1.20 ENSDART00000153126
ENSDART00000152895
ENSDART00000014190
sec31b
SEC31 homolog B, COPII coat complex component
chr17_-_14780578 1.19 ENSDART00000154690
si:ch211-266o15.1
si:ch211-266o15.1
chr3_+_13190012 1.19 ENSDART00000179747
ENSDART00000109876
ENSDART00000124824
ENSDART00000130261
sun1
Sad1 and UNC84 domain containing 1
chr12_-_22039350 1.18 ENSDART00000153187
thrab
thyroid hormone receptor alpha b
chr20_+_27713210 1.18 ENSDART00000132222
zbtb1
zinc finger and BTB domain containing 1
chr5_-_12587053 1.17 ENSDART00000162780
vsig10
V-set and immunoglobulin domain containing 10
chr1_+_2301961 1.16 ENSDART00000108919
ENSDART00000143361
ENSDART00000142944
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr4_-_18281070 1.16 ENSDART00000135330
ENSDART00000179075
ENSDART00000046871
uhrf1bp1l
UHRF1 binding protein 1-like
chr3_-_20793655 1.16 ENSDART00000163473
ENSDART00000159457
spop
speckle-type POZ protein
chr12_+_33320884 1.15 ENSDART00000188988
csnk1db
casein kinase 1, delta b
chr5_-_323712 1.15 ENSDART00000188793
HOOK3
hook microtubule tethering protein 3
chr24_+_37484661 1.15 ENSDART00000165125
ENSDART00000109221
wdr90
WD repeat domain 90
chr25_-_8138122 1.14 ENSDART00000104659
sergef
secretion regulating guanine nucleotide exchange factor
chr4_-_73562122 1.14 ENSDART00000174096
CU570689.2

chr4_-_73561848 1.13 ENSDART00000174210
CU570689.2

chr5_-_20135679 1.13 ENSDART00000079402
usp30
ubiquitin specific peptidase 30
chr20_+_13783040 1.12 ENSDART00000115329
ENSDART00000152497
lpgat1
lysophosphatidylglycerol acyltransferase 1
chr21_-_588858 1.12 ENSDART00000168983
TMEM38B
transmembrane protein 38B
chr7_+_14005111 1.10 ENSDART00000187365
furina
furin (paired basic amino acid cleaving enzyme) a
chr21_+_36623162 1.10 ENSDART00000027459
grk6
G protein-coupled receptor kinase 6
chr13_+_13945218 1.10 ENSDART00000089501
ENSDART00000142997
eif2ak3
eukaryotic translation initiation factor 2-alpha kinase 3
chr25_-_21894317 1.10 ENSDART00000089642
fbxo31
F-box protein 31
chr22_-_21897203 1.10 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr20_+_27712714 1.09 ENSDART00000008306
zbtb1
zinc finger and BTB domain containing 1
chr23_-_19103855 1.09 ENSDART00000016901
pard6b
par-6 partitioning defective 6 homolog beta (C. elegans)
chr20_+_47953047 1.07 ENSDART00000079734
hadhaa
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a
chr16_+_48714048 1.07 ENSDART00000148709
ENSDART00000150121
brd2b
bromodomain containing 2b
chr16_+_20167811 1.06 ENSDART00000004031
hacl1
2-hydroxyacyl-CoA lyase 1
chr22_+_18316144 1.06 ENSDART00000137985
gatad2ab
GATA zinc finger domain containing 2Ab
chr6_+_33537267 1.06 ENSDART00000040334
pik3r3b
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr21_-_18262287 1.06 ENSDART00000176716
vav2
vav 2 guanine nucleotide exchange factor
chr3_-_23596809 1.06 ENSDART00000156897
ube2z
ubiquitin-conjugating enzyme E2Z
chr18_-_41160975 1.05 ENSDART00000187517
CABZ01005876.1

chr13_+_24396666 1.05 ENSDART00000139197
ENSDART00000101200
zgc:153169
zgc:153169
chr5_-_37103487 1.04 ENSDART00000149211
il13ra2
interleukin 13 receptor, alpha 2
chr15_-_20125331 1.04 ENSDART00000152355
med13b
mediator complex subunit 13b
chr20_-_26391958 1.02 ENSDART00000078062
armt1
acidic residue methyltransferase 1
chr22_-_37796998 1.01 ENSDART00000124742
ENSDART00000191232
acap2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr5_-_27993972 1.01 ENSDART00000175819
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr14_-_38889840 1.00 ENSDART00000035779
zgc:101583
zgc:101583
chr2_+_52232630 0.99 ENSDART00000006216
plpp2a
phospholipid phosphatase 2a
chr4_+_15006217 0.99 ENSDART00000090837
zc3hc1
zinc finger, C3HC-type containing 1
chr5_-_32489796 0.98 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr7_+_1534820 0.97 ENSDART00000192997
tox4b
TOX high mobility group box family member 4 b
chr25_-_2723682 0.97 ENSDART00000113382
adpgk
ADP-dependent glucokinase
chr20_+_21391181 0.97 ENSDART00000185158
ENSDART00000049586
ENSDART00000024922
jag2b
jagged 2b
chr11_+_28218141 0.96 ENSDART00000043756
ephb2b
eph receptor B2b
chr13_+_9612395 0.96 ENSDART00000136689
ENSDART00000138362
slf2
SMC5-SMC6 complex localization factor 2
chr19_-_18313303 0.95 ENSDART00000164644
ENSDART00000167480
ENSDART00000163104
si:dkey-208k4.2
si:dkey-208k4.2
chr4_-_27897160 0.95 ENSDART00000066924
ENSDART00000066925
ENSDART00000193020
tbc1d22a
TBC1 domain family, member 22a
chr14_-_33945692 0.95 ENSDART00000168546
ENSDART00000189778
zdhhc24
zinc finger, DHHC-type containing 24
chr5_-_3991655 0.94 ENSDART00000159368
myo19
myosin XIX
chr16_-_42770064 0.94 ENSDART00000112879
slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr10_-_25328814 0.94 ENSDART00000123820
tmem135
transmembrane protein 135
chr5_-_8614217 0.93 ENSDART00000164844
rictora
RPTOR independent companion of MTOR, complex 2 a
chr1_+_41666611 0.93 ENSDART00000145789
fbxo41
F-box protein 41
chr16_-_35329803 0.92 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
ptprub
protein tyrosine phosphatase, receptor type, U, b
chr3_-_40836081 0.92 ENSDART00000143135
wipi2
WD repeat domain, phosphoinositide interacting 2
chr17_+_38030327 0.91 ENSDART00000085481
slc25a21
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr21_-_43474012 0.91 ENSDART00000065104
tmem185
transmembrane protein 185
chr2_-_27651674 0.90 ENSDART00000177402
tgs1
trimethylguanosine synthase 1
chr3_-_27880229 0.90 ENSDART00000151404
abat
4-aminobutyrate aminotransferase
chr12_-_10505986 0.90 ENSDART00000152672
zgc:152977
zgc:152977
chr5_-_39805874 0.89 ENSDART00000176202
ENSDART00000191683
rasgef1ba
RasGEF domain family, member 1Ba
chr9_+_17984358 0.87 ENSDART00000192399
akap11
A kinase (PRKA) anchor protein 11
chr11_+_42726712 0.87 ENSDART00000028955
tdrd3
tudor domain containing 3
chr16_-_54978981 0.87 ENSDART00000154023
wdtc1
WD and tetratricopeptide repeats 1
chr20_-_165818 0.86 ENSDART00000123860
si:ch211-241j12.3
si:ch211-241j12.3
chr7_+_71776905 0.85 ENSDART00000189745
ENSDART00000161344
ENSDART00000158782
nsun6
NOL1/NOP2/Sun domain family, member 6
chr2_-_42843797 0.84 ENSDART00000137913
adcy8
adenylate cyclase 8 (brain)
chr6_+_4371137 0.84 ENSDART00000168973
rbm26
RNA binding motif protein 26
chr16_-_22775480 0.84 ENSDART00000141778
ENSDART00000145585
ENSDART00000125963
ENSDART00000127570
pbxip1b
pre-B-cell leukemia homeobox interacting protein 1b
chr7_+_55149001 0.84 ENSDART00000148642
cdh31
cadherin 31
chr9_-_25366541 0.83 ENSDART00000021672
epc2
enhancer of polycomb homolog 2 (Drosophila)
chr16_+_11151699 0.83 ENSDART00000140674
cicb
capicua transcriptional repressor b
chr11_+_31680513 0.82 ENSDART00000139900
ENSDART00000040305
diaph3
diaphanous-related formin 3
chr10_+_20590190 0.82 ENSDART00000131819
letm2
leucine zipper-EF-hand containing transmembrane protein 2
chr9_+_29548630 0.80 ENSDART00000132295
rnf17
ring finger protein 17
chr7_+_41887429 0.80 ENSDART00000115090
gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr3_+_17616201 0.80 ENSDART00000156775
rab5c
RAB5C, member RAS oncogene family
chr11_-_843811 0.79 ENSDART00000173331
atg7
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr14_-_3944017 0.78 ENSDART00000055817
si:ch73-49o8.1
si:ch73-49o8.1
chr1_+_18863060 0.78 ENSDART00000139241
rnf38
ring finger protein 38
chr1_+_29183962 0.78 ENSDART00000113735
cars2
cysteinyl-tRNA synthetase 2, mitochondrial
chr8_-_13678415 0.78 ENSDART00000134153
ENSDART00000143331
si:dkey-258f14.3
si:dkey-258f14.3
chr11_+_45436703 0.77 ENSDART00000168295
ENSDART00000173293
sos1
son of sevenless homolog 1 (Drosophila)
chr21_-_23046606 0.76 ENSDART00000016167
zw10
zw10 kinetochore protein

Network of associatons between targets according to the STRING database.

First level regulatory network of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0051026 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.8 3.3 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.6 2.5 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.5 1.6 GO:0072579 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.5 2.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.4 1.2 GO:0044320 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.4 2.0 GO:0023041 neuronal signal transduction(GO:0023041)
0.4 2.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 1.5 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.3 2.1 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.3 1.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.3 1.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.3 1.6 GO:1990108 protein linear deubiquitination(GO:1990108)
0.3 1.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.3 2.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 1.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 1.2 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.2 1.2 GO:0007624 ultradian rhythm(GO:0007624)
0.2 1.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 3.7 GO:0032418 lysosome localization(GO:0032418)
0.2 0.9 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.2 1.3 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.2 3.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 1.4 GO:0048478 embryonic body morphogenesis(GO:0010172) replication fork protection(GO:0048478)
0.2 2.0 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 1.8 GO:0010888 negative regulation of cholesterol storage(GO:0010887) negative regulation of lipid storage(GO:0010888)
0.2 0.8 GO:0021543 substrate-dependent cell migration(GO:0006929) pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.2 1.9 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.2 1.3 GO:0048069 eye pigmentation(GO:0048069)
0.2 1.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 0.9 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.2 1.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 1.8 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.2 0.7 GO:0032801 receptor catabolic process(GO:0032801)
0.2 1.4 GO:0044211 CTP salvage(GO:0044211)
0.2 1.9 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.2 0.7 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 0.5 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.2 1.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 1.5 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.1 2.5 GO:0071166 ribonucleoprotein complex localization(GO:0071166)
0.1 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 2.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 1.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.8 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.7 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 1.0 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.6 GO:0006535 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.9 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 1.2 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.5 GO:0034505 tooth mineralization(GO:0034505)
0.1 3.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.4 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.4 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 3.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.7 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 2.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 1.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.5 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 3.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.5 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.6 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.5 GO:0003272 endocardial cushion formation(GO:0003272)
0.1 0.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.9 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.0 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.1 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.4 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.7 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.2 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 0.3 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.3 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.3 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 0.8 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.3 GO:0097033 respiratory chain complex III assembly(GO:0017062) protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) mitochondrial respiratory chain complex III assembly(GO:0034551) protein insertion into mitochondrial membrane(GO:0051204) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.3 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.4 GO:0045687 positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 1.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 2.8 GO:0051028 mRNA transport(GO:0051028)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 2.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 3.5 GO:0006405 RNA export from nucleus(GO:0006405)
0.1 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.8 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 1.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.3 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.6 GO:0030104 water homeostasis(GO:0030104)
0.1 0.3 GO:0030329 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.1 1.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 2.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 1.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 1.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0002902 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 2.2 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.9 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.5 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.9 GO:0001757 somite specification(GO:0001757)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 3.5 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 2.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 1.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.2 GO:0003094 glomerular filtration(GO:0003094)
0.0 2.2 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.8 GO:0071174 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0060972 left/right pattern formation(GO:0060972)
0.0 2.5 GO:0030048 actin filament-based movement(GO:0030048)
0.0 1.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 1.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.5 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0071047 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.5 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.4 GO:0051084 'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 1.4 GO:0006400 tRNA modification(GO:0006400)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0003403 optic vesicle formation(GO:0003403)
0.0 0.1 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.9 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.6 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 2.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.4 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 0.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 1.4 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 1.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.3 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.3 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.3 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 2.0 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.3 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.3 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.4 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 0.2 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 1.0 GO:0006096 glycolytic process(GO:0006096)
0.0 0.1 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0070897 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.1 GO:0019682 glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 2.6 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.3 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 3.7 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.8 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.3 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.0 GO:0032387 negative regulation of intracellular transport(GO:0032387)
0.0 0.7 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.2 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.1 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.4 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.3 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.0 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0043073 germ cell nucleus(GO:0043073)
0.5 2.7 GO:0034657 GID complex(GO:0034657)
0.4 1.2 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.3 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 2.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.3 3.7 GO:0002102 podosome(GO:0002102)
0.2 1.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 1.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 3.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.2 1.3 GO:0032019 mitochondrial cloud(GO:0032019)
0.2 0.6 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.2 2.1 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 2.5 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 2.6 GO:0005844 polysome(GO:0005844)
0.1 0.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 1.0 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 2.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.2 GO:0005876 spindle microtubule(GO:0005876)
0.1 3.5 GO:0005643 nuclear pore(GO:0005643)
0.1 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.3 GO:0031082 BLOC complex(GO:0031082)
0.0 0.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 2.3 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 2.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 1.9 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 1.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 1.3 GO:0016529 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 3.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 1.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 2.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 1.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.6 GO:0005819 spindle(GO:0005819)
0.0 1.0 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.6 GO:0005902 microvillus(GO:0005902)
0.0 2.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.2 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 1.1 GO:0005769 early endosome(GO:0005769)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 1.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 1.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.3 GO:0043186 P granule(GO:0043186)
0.0 0.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.6 GO:0000776 kinetochore(GO:0000776)
0.0 0.3 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0001729 ceramide kinase activity(GO:0001729)
0.5 1.6 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.5 1.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.5 2.0 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.5 3.4 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.5 1.4 GO:0036310 annealing helicase activity(GO:0036310)
0.5 2.3 GO:0034046 poly(G) binding(GO:0034046)
0.4 1.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4 3.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.4 1.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.4 1.4 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 3.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.3 2.8 GO:0005042 netrin receptor activity(GO:0005042)
0.3 1.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.3 2.3 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.2 0.7 GO:0045545 syndecan binding(GO:0045545)
0.2 1.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 2.5 GO:0004046 aminoacylase activity(GO:0004046)
0.2 2.2 GO:0035198 miRNA binding(GO:0035198)
0.2 1.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.2 0.8 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 2.0 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.2 0.9 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990) RNA polymerase I core binding(GO:0001042)
0.2 2.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 1.4 GO:0004849 uridine kinase activity(GO:0004849)
0.2 1.0 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.9 GO:0043495 protein anchor(GO:0043495)
0.2 0.8 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.2 2.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 0.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 2.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.6 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 1.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 2.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 3.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.5 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.6 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 2.1 GO:0002039 p53 binding(GO:0002039)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.1 GO:0030332 cyclin binding(GO:0030332)
0.1 1.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.4 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.3 GO:0030882 lipid antigen binding(GO:0030882)
0.1 1.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.2 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 7.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 1.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.4 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.1 1.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.2 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.1 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.1 2.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 3.7 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.5 GO:0034452 dynactin binding(GO:0034452)
0.1 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.3 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.1 0.3 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.1 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.5 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.3 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.2 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.5 GO:0008483 transaminase activity(GO:0008483)
0.0 1.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 1.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.1 GO:0043022 ribosome binding(GO:0043022)
0.0 1.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 6.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 4.0 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.9 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.2 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 2.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 2.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 1.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 5.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 1.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 1.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.6 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 3.8 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.5 GO:0015293 symporter activity(GO:0015293)
0.0 1.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 5.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.4 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.2 ST STAT3 PATHWAY STAT3 Pathway
0.1 1.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 0.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 3.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 3.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.4 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 PID FOXO PATHWAY FoxO family signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 4.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 3.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 3.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 7.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+