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PRJNA195909:zebrafish embryo and larva development

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Results for msx1a

Z-value: 1.17

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Transcription factors associated with msx1a

Gene Symbol Gene ID Gene Info
msx1a
ENSDARG00000116118 muscle segment homeobox 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
msx1adr11_v1_chr14_-_12822_12847-0.845.1e-03Click!

Activity profile of msx1a motif

Sorted Z-values of msx1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_21362071 3.53 ENSDART00000125167
avd
avidin
chr21_+_25777425 3.51 ENSDART00000021620
cldnd
claudin d
chr10_-_21362320 3.46 ENSDART00000189789
avd
avidin
chr19_-_20403507 3.45 ENSDART00000052603
ENSDART00000137590
dazl
deleted in azoospermia-like
chr19_-_20403845 3.22 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
dazl
deleted in azoospermia-like
chr11_-_6452444 3.05 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr14_+_34490445 2.92 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr9_-_35633827 2.90 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr10_-_34915886 2.79 ENSDART00000141201
ENSDART00000002166
ccna1
cyclin A1
chr18_-_40708537 2.75 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr24_+_12835935 2.65 ENSDART00000114762
nanog
nanog homeobox
chr8_+_45334255 2.57 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr10_-_34916208 2.46 ENSDART00000187371
ccna1
cyclin A1
chr20_-_23426339 2.45 ENSDART00000004625
zar1
zygote arrest 1
chr10_-_25217347 2.32 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr11_-_44801968 2.15 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr1_-_18811517 2.05 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr10_+_6884627 1.99 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr25_-_32869794 1.98 ENSDART00000162784
tmem266
transmembrane protein 266
chr10_-_34002185 1.93 ENSDART00000046599
zar1l
zygote arrest 1-like
chr15_-_25099679 1.82 ENSDART00000154628
rflnb
refilin B
chr16_+_39159752 1.79 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr2_+_6253246 1.72 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr11_+_18183220 1.61 ENSDART00000113468
LO018315.10

chr7_-_48263516 1.56 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
rbpms2b
RNA binding protein with multiple splicing 2b
chr11_+_18130300 1.56 ENSDART00000169146
zgc:175135
zgc:175135
chr11_+_18157260 1.56 ENSDART00000144659
zgc:173545
zgc:173545
chr19_-_8768564 1.48 ENSDART00000170416
si:ch73-350k19.1
si:ch73-350k19.1
chr19_-_20403318 1.48 ENSDART00000136826
dazl
deleted in azoospermia-like
chr8_+_41037541 1.38 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr19_-_19556778 1.38 ENSDART00000164060
tax1bp1a
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr12_-_33579873 1.35 ENSDART00000184661
tdrkh
tudor and KH domain containing
chr1_-_55248496 1.32 ENSDART00000098615
nanos3
nanos homolog 3
chr14_+_23184517 1.28 ENSDART00000181410
enox2
ecto-NOX disulfide-thiol exchanger 2
chr6_-_43283122 1.27 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr17_+_16046132 1.23 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr20_-_45060241 1.23 ENSDART00000185227
klhl29
kelch-like family member 29
chr5_+_6954162 1.17 ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr23_+_38957472 1.14 ENSDART00000193836
ATP9A
ATPase phospholipid transporting 9A (putative)
chr8_-_20230559 1.12 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr10_-_13343831 1.10 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr16_-_16120941 1.04 ENSDART00000131227
ankib1b
ankyrin repeat and IBR domain containing 1b
chr2_-_21167652 1.04 ENSDART00000185792
bmi1b
bmi1 polycomb ring finger oncogene 1b
chr23_-_40194732 0.98 ENSDART00000164931
tgm1l2
transglutaminase 1 like 2
chr11_+_31864921 0.95 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr6_+_21001264 0.95 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr10_-_32494499 0.93 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr21_-_28640316 0.91 ENSDART00000128237
nrg2a
neuregulin 2a
chr14_-_32631013 0.90 ENSDART00000176815
atp11c
ATPase phospholipid transporting 11C
chr10_+_42690374 0.90 ENSDART00000123496
rhobtb2b
Rho-related BTB domain containing 2b
chr18_-_43884044 0.90 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr3_+_28860283 0.90 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr16_+_33163858 0.89 ENSDART00000101943
rragca
Ras-related GTP binding Ca
chr12_+_21298317 0.87 ENSDART00000178562
ca10a
carbonic anhydrase Xa
chr1_+_18811679 0.87 ENSDART00000078610
slc25a51a
solute carrier family 25, member 51a
chr17_+_16046314 0.86 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr10_-_32494304 0.85 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr8_-_20230802 0.84 ENSDART00000063400
mllt1a
MLLT1, super elongation complex subunit a
chr4_-_72638972 0.84 ENSDART00000193312
CABZ01054394.1

chr2_-_57076687 0.83 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr24_-_25144441 0.83 ENSDART00000152104
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr21_-_3853204 0.79 ENSDART00000188829
st6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr5_-_67629263 0.76 ENSDART00000133753
zbtb20
zinc finger and BTB domain containing 20
chr17_+_25856671 0.75 ENSDART00000064817
wapla
WAPL cohesin release factor a
chr9_-_21460164 0.75 ENSDART00000133469
zmym2
zinc finger, MYM-type 2
chr15_-_16177603 0.73 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr23_-_31913069 0.73 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr19_+_15441022 0.72 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr20_-_19511016 0.70 ENSDART00000168521
snx17
sorting nexin 17
chr20_-_28800999 0.69 ENSDART00000049462
rab15
RAB15, member RAS oncogene family
chr3_+_18807006 0.69 ENSDART00000180091
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr23_+_38251864 0.69 ENSDART00000183498
ENSDART00000129593
znf217
zinc finger protein 217
chr9_+_34331368 0.67 ENSDART00000147913
pou2f1b
POU class 2 homeobox 1b
chr2_-_33645411 0.66 ENSDART00000114663
b4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr7_+_38089650 0.65 ENSDART00000052365
cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr10_-_28513861 0.65 ENSDART00000177781
bbx
bobby sox homolog (Drosophila)
chr2_-_38206034 0.62 ENSDART00000144518
ENSDART00000137395
acin1a
apoptotic chromatin condensation inducer 1a
chr3_-_26805455 0.62 ENSDART00000180648
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr6_-_37744430 0.61 ENSDART00000150177
ENSDART00000149722
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr20_-_40758410 0.61 ENSDART00000183031
cx34.5
connexin 34.5
chr11_+_12052791 0.59 ENSDART00000158479
si:ch211-156l18.8
si:ch211-156l18.8
chr5_+_60928576 0.59 ENSDART00000131041
doc2b
double C2-like domains, beta
chr15_-_26931541 0.58 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr25_-_27621268 0.57 ENSDART00000146205
ENSDART00000073511
hyal6
hyaluronoglucosaminidase 6
chr24_-_30843250 0.56 ENSDART00000162920
ptbp2a
polypyrimidine tract binding protein 2a
chr4_-_27099224 0.56 ENSDART00000048383
creld2
cysteine-rich with EGF-like domains 2
chr13_-_36911118 0.54 ENSDART00000048739
trim9
tripartite motif containing 9
chr7_-_12464412 0.52 ENSDART00000178723
adamtsl3
ADAMTS-like 3
chr7_+_27603211 0.51 ENSDART00000148782
cyp2r1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr19_-_19379084 0.51 ENSDART00000165206
smarcc1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr2_+_37227011 0.50 ENSDART00000126587
ENSDART00000084958
samd7
sterile alpha motif domain containing 7
chr11_-_29768054 0.50 ENSDART00000079117
plekha3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr16_+_35661771 0.49 ENSDART00000161393
map7d1a
MAP7 domain containing 1a
chr19_-_25119443 0.47 ENSDART00000148953
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr2_+_50626476 0.47 ENSDART00000018150
neurod6b
neuronal differentiation 6b
chr2_-_55298075 0.46 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr16_+_42471455 0.45 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr16_-_17347727 0.45 ENSDART00000144392
zyx
zyxin
chr20_-_29864390 0.45 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr8_-_10961991 0.43 ENSDART00000139603
trim33
tripartite motif containing 33
chr5_+_68807170 0.43 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr23_-_31913231 0.43 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr7_-_23768234 0.43 ENSDART00000173981
si:ch211-200p22.4
si:ch211-200p22.4
chr2_+_20793982 0.42 ENSDART00000014785
prg4a
proteoglycan 4a
chr25_+_11456696 0.42 ENSDART00000171408
AGBL1
si:ch73-141f14.1
chr3_-_26806032 0.42 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr15_-_8665662 0.40 ENSDART00000090675
arhgap35a
Rho GTPase activating protein 35a
chr1_-_47071979 0.39 ENSDART00000160817
itsn1
intersectin 1 (SH3 domain protein)
chr21_+_34088110 0.38 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr8_-_46894362 0.35 ENSDART00000111124
acot7
acyl-CoA thioesterase 7
chr2_+_50608099 0.34 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr19_-_38830582 0.34 ENSDART00000189966
ENSDART00000183055
adgrb2
adhesion G protein-coupled receptor B2
chr22_-_7129631 0.33 ENSDART00000171359
asic1b
acid-sensing (proton-gated) ion channel 1b
chr18_+_10884996 0.31 ENSDART00000147613
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr15_-_6247775 0.28 ENSDART00000148350
dscamb
Down syndrome cell adhesion molecule b
chr19_+_28187480 0.28 ENSDART00000183825
irx4b
iroquois homeobox 4b
chr24_+_40860320 0.27 ENSDART00000161351
gorasp1b
golgi reassembly stacking protein 1b
chr18_+_15644559 0.27 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr1_+_30100257 0.25 ENSDART00000134311
vps8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr20_+_28803977 0.25 ENSDART00000153351
ENSDART00000038149
fntb
farnesyltransferase, CAAX box, beta
chr10_-_21955231 0.24 ENSDART00000183695
FO744833.2

chr23_-_1348933 0.24 ENSDART00000168981
CABZ01078120.1

chr20_+_41021054 0.23 ENSDART00000146052
man1a1
mannosidase, alpha, class 1A, member 1
chr3_-_32898626 0.23 ENSDART00000103201
kat7a
K(lysine) acetyltransferase 7a
chr3_+_56366395 0.21 ENSDART00000154367
cacng5b
calcium channel, voltage-dependent, gamma subunit 5b
chr6_+_3280939 0.20 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr16_+_28994709 0.20 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr24_-_4782052 0.19 ENSDART00000149911
agtr1b
angiotensin II receptor, type 1b
chr11_+_33312601 0.18 ENSDART00000188024
cntnap5l
contactin associated protein-like 5 like
chr13_+_38990939 0.17 ENSDART00000145979
col19a1
collagen, type XIX, alpha 1
chr12_+_6195191 0.17 ENSDART00000043236
ENSDART00000186420
prkg1b
protein kinase, cGMP-dependent, type Ib
chr18_-_22094102 0.16 ENSDART00000100904
pard6a
par-6 family cell polarity regulator alpha
chr12_-_18872927 0.15 ENSDART00000187717
shisa8b
shisa family member 8b
chr6_-_39649504 0.14 ENSDART00000179960
ENSDART00000190951
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr13_-_36184476 0.14 ENSDART00000057185
map3k9
mitogen-activated protein kinase kinase kinase 9
chr16_+_31827502 0.14 ENSDART00000045210
mlf2
myeloid leukemia factor 2
chr7_-_31940590 0.13 ENSDART00000131009
bdnf
brain-derived neurotrophic factor
chr13_+_38430466 0.13 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr2_+_39021282 0.12 ENSDART00000056577
RBP1 (1 of many)
si:ch211-119o8.7
chr2_+_31804582 0.12 ENSDART00000086646
rnf182
ring finger protein 182
chr13_+_2625150 0.11 ENSDART00000164177
plpp4
phospholipid phosphatase 4
chr10_+_40660772 0.11 ENSDART00000148007
taar19l
trace amine associated receptor 19l
chr14_-_2933185 0.10 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr3_+_32365811 0.09 ENSDART00000155967
ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr15_+_41027466 0.09 ENSDART00000075940
mtnr1ba
melatonin receptor type 1Ba
chr8_-_25034411 0.09 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr22_+_28320792 0.08 ENSDART00000160562
ENSDART00000164138
impg2b
impg2b
interphotoreceptor matrix proteoglycan 2b
interphotoreceptor matrix proteoglycan 2b
chr20_-_32110882 0.07 ENSDART00000030324
grm1a
glutamate receptor, metabotropic 1a
chr17_+_26543690 0.07 ENSDART00000156417
sparcl2
SPARC-like 2
chr5_+_60590796 0.06 ENSDART00000159859
tmem132e
transmembrane protein 132E
chr16_-_47483142 0.06 ENSDART00000147072
cthrc1b
collagen triple helix repeat containing 1b
chr16_+_54263921 0.06 ENSDART00000002856
drd2l
dopamine receptor D2 like
chr21_+_30746348 0.06 ENSDART00000050172
trpc2b
transient receptor potential cation channel, subfamily C, member 2b
chr6_+_102506 0.06 ENSDART00000172678
ldlrb
low density lipoprotein receptor b
chr22_+_1092479 0.05 ENSDART00000170119
guca1e
guanylate cyclase activator 1e
chr20_-_40755614 0.04 ENSDART00000061247
cx32.3
connexin 32.3
chr7_-_31941330 0.04 ENSDART00000144682
bdnf
brain-derived neurotrophic factor
chr6_-_14292307 0.04 ENSDART00000177852
ENSDART00000061745
inpp4ab
inositol polyphosphate-4-phosphatase type I Ab
chr10_-_36253958 0.04 ENSDART00000126288
or110-2
odorant receptor, family D, subfamily 110, member 2
chr19_-_19871211 0.03 ENSDART00000170980
evx1
even-skipped homeobox 1
chr16_+_31827653 0.03 ENSDART00000187261
mlf2
myeloid leukemia factor 2
chr17_+_31914877 0.02 ENSDART00000177801
FAM196A (1 of many)
family with sequence similarity 196 member A
chr18_-_29896367 0.02 ENSDART00000191303
cmc2
C-x(9)-C motif containing 2
chr23_+_39695827 0.01 ENSDART00000113893
ENSDART00000186679
tmco4
transmembrane and coiled-coil domains 4
chr23_+_33963619 0.00 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of msx1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.2 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
1.0 2.9 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.7 3.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.6 1.8 GO:1900157 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.4 1.8 GO:0060074 synapse maturation(GO:0060074)
0.3 1.4 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.3 1.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 1.6 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.3 1.3 GO:0007624 ultradian rhythm(GO:0007624)
0.3 0.8 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.2 2.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.9 GO:0060347 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.1 1.8 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 2.1 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.9 GO:0034063 stress granule assembly(GO:0034063)
0.1 2.0 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.1 5.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.7 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.5 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.1 1.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.5 GO:0035627 ceramide transport(GO:0035627)
0.1 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.1 2.7 GO:0060968 regulation of gene silencing(GO:0060968)
0.1 0.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.3 GO:0070207 protein homotrimerization(GO:0070207)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.9 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 1.2 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.7 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 1.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.9 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.9 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 2.4 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.4 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 1.0 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 0.8 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.4 GO:0001757 somite specification(GO:0001757)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 1.6 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.7 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
1.0 2.9 GO:0097189 apoptotic body(GO:0097189)
0.2 0.9 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 3.3 GO:0043186 P granule(GO:0043186)
0.1 3.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.8 GO:0045180 basal cortex(GO:0045180)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 2.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.0 GO:0035102 PRC1 complex(GO:0035102)
0.0 4.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.4 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 2.3 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.0 GO:0009374 biotin binding(GO:0009374)
0.9 8.2 GO:0008494 translation activator activity(GO:0008494)
0.5 1.8 GO:0031005 filamin binding(GO:0031005)
0.3 0.8 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 2.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 3.0 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.2 1.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 1.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 1.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 1.6 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 0.5 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 5.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.8 GO:0019894 kinesin binding(GO:0019894)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 2.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 1.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.3 GO:0032052 bile acid binding(GO:0032052)
0.0 0.6 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 2.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 2.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 6.1 GO:0042802 identical protein binding(GO:0042802)
0.0 0.7 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 4.9 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.1 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type