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PRJNA195909:zebrafish embryo and larva development

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Results for mycn

Z-value: 1.24

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Transcription factors associated with mycn

Gene Symbol Gene ID Gene Info
mycn
ENSDARG00000006837 MYCN proto-oncogene, bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mycndr11_v1_chr20_+_33294428_33294428-0.482.0e-01Click!

Activity profile of mycn motif

Sorted Z-values of mycn motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_14277003 1.97 ENSDART00000006628
zgc:173742
zgc:173742
chr3_+_24595922 1.89 ENSDART00000169405
si:dkey-68o6.5
si:dkey-68o6.5
chr15_-_17099560 1.80 ENSDART00000101724
mos
v-mos Moloney murine sarcoma viral oncogene homolog
chr23_+_32101361 1.77 ENSDART00000138849
zgc:56699
zgc:56699
chr23_+_38159715 1.61 ENSDART00000137969
zgc:112994
zgc:112994
chr22_-_20695237 1.51 ENSDART00000112722
org
oogenesis-related gene
chr16_-_21489514 1.50 ENSDART00000149525
ENSDART00000148517
ENSDART00000146914
ENSDART00000186493
ENSDART00000193081
ENSDART00000186017
mpp6a
membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)
chr13_-_12021566 1.34 ENSDART00000125430
pprc1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr5_+_68807170 1.33 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr14_-_8940499 1.30 ENSDART00000129030
zgc:153681
zgc:153681
chr1_+_12195700 1.28 ENSDART00000040307
tdrd7a
tudor domain containing 7 a
chr4_-_2945306 1.26 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr13_-_15142280 1.25 ENSDART00000163132
rab11fip5a
RAB11 family interacting protein 5a (class I)
chr21_-_14832369 1.23 ENSDART00000144859
pus1
pseudouridylate synthase 1
chr25_+_17689565 1.23 ENSDART00000171965
galnt18a
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr11_-_12800945 1.20 ENSDART00000191178
txlng
taxilin gamma
chr18_-_11595567 1.20 ENSDART00000098565
CRACR2A
calcium release activated channel regulator 2A
chr12_-_22238004 1.17 ENSDART00000038310
ormdl3
ORMDL sphingolipid biosynthesis regulator 3
chr11_-_12801157 1.16 ENSDART00000103449
txlng
taxilin gamma
chr5_-_43859148 1.14 ENSDART00000162746
ENSDART00000128763
si:ch211-204c21.1
si:ch211-204c21.1
chr15_+_44250335 1.13 ENSDART00000186162
ENSDART00000193503
ENSDART00000180275
zgc:162962
zgc:162962
chr9_-_12888082 1.12 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr16_+_13860299 1.08 ENSDART00000121998
grwd1
glutamate-rich WD repeat containing 1
chr10_-_45029041 1.06 ENSDART00000167878
polm
polymerase (DNA directed), mu
chr24_+_34069675 1.04 ENSDART00000143995
si:ch211-190p8.2
si:ch211-190p8.2
chr13_-_35907768 1.03 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr13_-_4992395 1.03 ENSDART00000102651
nolc1
nucleolar and coiled-body phosphoprotein 1
chr3_+_3810919 1.02 ENSDART00000056035
FQ311927.1

chr18_+_14645568 1.02 ENSDART00000138995
ENSDART00000147351
vps9d1
VPS9 domain containing 1
chr9_+_20780813 1.02 ENSDART00000142787
fam46c
family with sequence similarity 46, member C
chr13_-_25408387 1.02 ENSDART00000002741
itprip
inositol 1,4,5-trisphosphate receptor interacting protein
chr22_+_17261801 1.01 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tdrd5
tudor domain containing 5
chr1_-_8917902 0.96 ENSDART00000137900
grin2ab
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr19_-_7043355 0.96 ENSDART00000104845
tapbp.1
TAP binding protein (tapasin), tandem duplicate 1
chr5_-_16475374 0.95 ENSDART00000134274
ENSDART00000136004
piwil2
piwi-like RNA-mediated gene silencing 2
chr24_-_10394277 0.94 ENSDART00000127568
ankha
ANKH inorganic pyrophosphate transport regulator a
chr11_+_6010177 0.93 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
gtpbp3
GTP binding protein 3, mitochondrial
chr13_+_31402067 0.92 ENSDART00000019202
tdrd9
tudor domain containing 9
chr5_-_20123002 0.91 ENSDART00000026516
pxmp2
peroxisomal membrane protein 2
chr21_-_22122312 0.90 ENSDART00000101726
slc35f2
solute carrier family 35, member F2
chr16_+_40954481 0.88 ENSDART00000058587
gbp
glycogen synthase kinase binding protein
chr12_-_33359052 0.86 ENSDART00000135943
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr2_-_39036604 0.86 ENSDART00000129963
rbp1
retinol binding protein 1b, cellular
chr6_+_38626926 0.84 ENSDART00000190339
atp10a
ATPase phospholipid transporting 10A
chr9_+_20781047 0.84 ENSDART00000139174
fam46c
family with sequence similarity 46, member C
chr20_+_42537768 0.84 ENSDART00000134066
ENSDART00000153434
si:dkeyp-93d12.1
si:dkeyp-93d12.1
chr1_-_55750208 0.84 ENSDART00000142244
dnajb1b
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr21_-_19919918 0.83 ENSDART00000137307
ENSDART00000142523
ENSDART00000065670
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr11_+_6009984 0.83 ENSDART00000185680
gtpbp3
GTP binding protein 3, mitochondrial
chr12_-_33359654 0.83 ENSDART00000001907
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr4_-_26032741 0.81 ENSDART00000188058
usp44
ubiquitin specific peptidase 44
chr5_-_26247215 0.81 ENSDART00000136806
erap1b
endoplasmic reticulum aminopeptidase 1b
chr23_+_30730121 0.80 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr7_+_20030888 0.79 ENSDART00000192808
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr23_+_19594608 0.78 ENSDART00000134865
slmapb
sarcolemma associated protein b
chr3_+_37824268 0.77 ENSDART00000137038
asic2
acid-sensing (proton-gated) ion channel 2
chr6_-_29377092 0.76 ENSDART00000078665
tmem131
transmembrane protein 131
chr7_-_58178807 0.76 ENSDART00000188531
nsmaf
neutral sphingomyelinase (N-SMase) activation associated factor
chr22_-_28777557 0.75 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr1_+_52633367 0.74 ENSDART00000134658
slc44a1a
solute carrier family 44 (choline transporter), member 1a
chr20_-_45772306 0.74 ENSDART00000062092
trmt6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr9_+_29548630 0.74 ENSDART00000132295
rnf17
ring finger protein 17
chr19_-_8940068 0.73 ENSDART00000043507
ciarta
circadian associated repressor of transcription a
chr5_-_54714525 0.73 ENSDART00000150138
ENSDART00000150070
ccnb1
cyclin B1
chr7_-_28647959 0.73 ENSDART00000150148
slc7a6
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr12_-_30359498 0.73 ENSDART00000152981
ENSDART00000189988
tdrd1
tudor domain containing 1
chr13_+_15701849 0.73 ENSDART00000003517
trmt61a
tRNA methyltransferase 61A
chr8_-_29851706 0.72 ENSDART00000149297
slc20a2
solute carrier family 20 (phosphate transporter), member 2
chr4_-_14192254 0.72 ENSDART00000143804
pus7l
pseudouridylate synthase 7-like
chr5_+_872299 0.72 ENSDART00000130042
fubp3
far upstream element (FUSE) binding protein 3
chr3_+_34120191 0.71 ENSDART00000020017
ENSDART00000151700
aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr5_+_62356304 0.71 ENSDART00000148381
aspa
aspartoacylase
chr5_-_54714789 0.71 ENSDART00000063357
ccnb1
cyclin B1
chr8_+_52377516 0.70 ENSDART00000115398
arid5a
AT rich interactive domain 5A (MRF1-like)
chr24_-_20208474 0.69 ENSDART00000139329
cry-dash
cryptochrome DASH
chr8_+_21280360 0.68 ENSDART00000144488
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr14_+_41409697 0.68 ENSDART00000173335
bcorl1
BCL6 corepressor-like 1
chr1_+_29664336 0.68 ENSDART00000088290
raph1b
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b
chr23_+_17522867 0.68 ENSDART00000002714
slc17a9b
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr14_+_16151636 0.68 ENSDART00000159352
polr1a
polymerase (RNA) I polypeptide A
chr9_-_12652984 0.67 ENSDART00000052256
sumo3b
small ubiquitin-like modifier 3b
chr21_+_19330774 0.67 ENSDART00000109412
helq
helicase, POLQ like
chr16_-_42175617 0.67 ENSDART00000084715
alkbh8
alkB homolog 8, tRNA methyltransferase
chr5_-_40190949 0.67 ENSDART00000175588
wdfy3
WD repeat and FYVE domain containing 3
chr20_-_48470599 0.66 ENSDART00000166857
CABZ01059120.1

chr24_-_38644937 0.66 ENSDART00000170194
slc6a16b
solute carrier family 6, member 16b
chr21_+_6114709 0.66 ENSDART00000065858
fpgs
folylpolyglutamate synthase
chr5_-_13167097 0.66 ENSDART00000149700
ENSDART00000030213
mapk1
mitogen-activated protein kinase 1
chr7_-_8961941 0.66 ENSDART00000111002
si:ch211-74f19.2
si:ch211-74f19.2
chr5_+_13521081 0.66 ENSDART00000171975
si:ch211-230g14.6
si:ch211-230g14.6
chr19_+_20201254 0.65 ENSDART00000010140
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr5_-_30080332 0.64 ENSDART00000140049
bco2a
beta-carotene oxygenase 2a
chr16_-_42186093 0.64 ENSDART00000076030
fbl
fibrillarin
chr25_-_32869794 0.64 ENSDART00000162784
tmem266
transmembrane protein 266
chr20_+_25626479 0.63 ENSDART00000143883
ppat
phosphoribosyl pyrophosphate amidotransferase
chr5_-_55914268 0.63 ENSDART00000014049
wdr36
WD repeat domain 36
chr8_+_26396552 0.62 ENSDART00000087151
amt
aminomethyltransferase
chr13_-_35908275 0.62 ENSDART00000013961
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr17_+_24318753 0.61 ENSDART00000064083
otx1
orthodenticle homeobox 1
chr13_-_9367647 0.61 ENSDART00000083362
ENSDART00000144146
si:dkey-33c12.4
si:dkey-33c12.4
chr7_+_47243564 0.61 ENSDART00000098942
ENSDART00000162237
znf507
zinc finger protein 507
chr7_-_6438544 0.61 ENSDART00000173180
zgc:165555
zgc:165555
chr3_-_15131438 0.61 ENSDART00000131720
xpo6
exportin 6
chr5_+_31791001 0.60 ENSDART00000043010
slc25a25b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr12_-_9700605 0.60 ENSDART00000161063
heatr1
HEAT repeat containing 1
chr24_+_36317544 0.60 ENSDART00000048640
ENSDART00000156096
pus3
pseudouridylate synthase 3
chr2_+_205763 0.60 ENSDART00000160164
ENSDART00000101071
zgc:113293
zgc:113293
chr15_-_14589677 0.59 ENSDART00000172195
coq8b
coenzyme Q8B
chr10_+_35002786 0.59 ENSDART00000099552
exosc8
exosome component 8
chr7_-_30779575 0.59 ENSDART00000004782
mphosph10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr25_-_35296165 0.59 ENSDART00000018107
fancf
Fanconi anemia, complementation group F
chr1_-_40015782 0.59 ENSDART00000157425
ENSDART00000159238
cdk2ap2
cyclin-dependent kinase 2 associated protein 2
chr19_-_30800004 0.59 ENSDART00000128560
ENSDART00000045504
ENSDART00000125893
trit1
tRNA isopentenyltransferase 1
chr15_-_26089012 0.58 ENSDART00000152243
ENSDART00000140214
dph1
diphthamide biosynthesis 1
chr5_+_3927989 0.58 ENSDART00000030125
znhit3
zinc finger, HIT-type containing 3
chr8_+_40275830 0.58 ENSDART00000164414
orai1a
ORAI calcium release-activated calcium modulator 1a
chr18_+_27489595 0.58 ENSDART00000182018
tp53i11b
tumor protein p53 inducible protein 11b
chr3_-_18805225 0.58 ENSDART00000133471
ENSDART00000131758
msrb1a
methionine sulfoxide reductase B1a
chr18_+_6638974 0.58 ENSDART00000162398
c2cd5
C2 calcium-dependent domain containing 5
chr14_+_16151368 0.56 ENSDART00000160973
polr1a
polymerase (RNA) I polypeptide A
chr1_-_19648227 0.56 ENSDART00000054574
polr1e
polymerase (RNA) I polypeptide E
chr2_-_48826707 0.56 ENSDART00000134711
svilb
supervillin b
chr12_-_17602958 0.56 ENSDART00000134690
ENSDART00000028090
eif2ak1
eukaryotic translation initiation factor 2-alpha kinase 1
chr18_-_11729 0.56 ENSDART00000159781
WHAMM
WAS protein homolog associated with actin, golgi membranes and microtubules
chr7_+_55292959 0.56 ENSDART00000147539
ENSDART00000073555
ctu2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr18_-_12612699 0.56 ENSDART00000090335
hipk2
homeodomain interacting protein kinase 2
chr13_+_46803979 0.56 ENSDART00000159260
CU695232.1

chr5_-_8765428 0.56 ENSDART00000167793
mybbp1a
MYB binding protein (P160) 1a
chr5_-_10082244 0.56 ENSDART00000036421
chek2
checkpoint kinase 2
chr10_+_575929 0.55 ENSDART00000129856
smad4a
SMAD family member 4a
chr25_-_8625601 0.55 ENSDART00000155280
GDPGP1
zgc:153343
chr13_-_35976986 0.55 ENSDART00000075299
zgc:153911
zgc:153911
chr10_+_32066537 0.55 ENSDART00000124166
si:dkey-250d21.1
si:dkey-250d21.1
chr25_-_35101673 0.55 ENSDART00000140864
zgc:162611
zgc:162611
chr9_+_23770666 0.54 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3
chr11_-_26375575 0.54 ENSDART00000079255
utp3
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr18_+_6638726 0.54 ENSDART00000142755
ENSDART00000167781
c2cd5
C2 calcium-dependent domain containing 5
chr20_+_42565049 0.54 ENSDART00000061101
igf2r
insulin-like growth factor 2 receptor
chr14_+_22076596 0.54 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
slc43a1a
solute carrier family 43 (amino acid system L transporter), member 1a
chr20_-_51656512 0.54 ENSDART00000129965
LO018154.1

chr3_-_48612078 0.54 ENSDART00000169923
ndel1b
nudE neurodevelopment protein 1-like 1b
chr2_+_12255568 0.53 ENSDART00000184164
ENSDART00000013454
prtfdc1
phosphoribosyl transferase domain containing 1
chr2_-_11027258 0.53 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
ssbp3a
single stranded DNA binding protein 3a
chr17_-_29249258 0.53 ENSDART00000031458
traf3
TNF receptor-associated factor 3
chr8_-_13678415 0.53 ENSDART00000134153
ENSDART00000143331
si:dkey-258f14.3
si:dkey-258f14.3
chr3_-_9722603 0.53 ENSDART00000168234
crebbpb
CREB binding protein b
chr25_-_8138122 0.53 ENSDART00000104659
sergef
secretion regulating guanine nucleotide exchange factor
chr20_-_33705044 0.53 ENSDART00000166573
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr18_-_38244871 0.52 ENSDART00000076399
nat10
N-acetyltransferase 10
chr5_-_41933912 0.52 ENSDART00000097574
ncor1
nuclear receptor corepressor 1
chr18_-_38245062 0.52 ENSDART00000189092
nat10
N-acetyltransferase 10
chr18_-_20608025 0.52 ENSDART00000090156
ENSDART00000151980
bcl2l13
BCL2 like 13
chr1_-_45042210 0.51 ENSDART00000073694
smu1b
SMU1, DNA replication regulator and spliceosomal factor b
chr25_-_35101396 0.51 ENSDART00000138865
zgc:162611
zgc:162611
chr7_+_22792132 0.51 ENSDART00000135207
ENSDART00000146801
rbm4.3
RNA binding motif protein 4.3
chr6_-_23619428 0.51 ENSDART00000053126
aanat1
arylalkylamine N-acetyltransferase 1
chr25_+_7346800 0.50 ENSDART00000154404
peak1
pseudopodium-enriched atypical kinase 1
chr6_-_15065376 0.50 ENSDART00000087797
tgfbrap1
transforming growth factor, beta receptor associated protein 1
chr17_+_17764979 0.50 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr1_+_34203817 0.50 ENSDART00000191432
ENSDART00000046094
arl6
ADP-ribosylation factor-like 6
chr13_+_48358467 0.50 ENSDART00000171080
ENSDART00000162531
msh6
mutS homolog 6 (E. coli)
chr5_+_57210237 0.50 ENSDART00000167660
pja2
praja ring finger ubiquitin ligase 2
chr5_-_32338866 0.50 ENSDART00000017956
ENSDART00000047670
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr20_-_154989 0.50 ENSDART00000064542
rpf2
ribosome production factor 2 homolog
chr3_+_13929860 0.49 ENSDART00000164179
syce2
synaptonemal complex central element protein 2
chr3_-_31833266 0.49 ENSDART00000084932
ENSDART00000183617
map3k3
mitogen-activated protein kinase kinase kinase 3
chr4_+_2482046 0.49 ENSDART00000103371
zdhhc17
zinc finger, DHHC-type containing 17
chr7_-_49800755 0.49 ENSDART00000180072
fjx1
four jointed box 1
chr6_-_7735153 0.49 ENSDART00000151545
slc25a38b
solute carrier family 25, member 38b
chr12_-_31724198 0.49 ENSDART00000153056
ENSDART00000165299
ENSDART00000137464
ENSDART00000080173
srsf2a
serine/arginine-rich splicing factor 2a
chr20_+_38458084 0.49 ENSDART00000020153
ENSDART00000135912
coq8a
coenzyme Q8A
chr13_-_31370184 0.49 ENSDART00000034829
rrp12
ribosomal RNA processing 12 homolog
chr17_-_31819837 0.48 ENSDART00000160281
abraxas2b
abraxas 2b, BRISC complex subunit
chr3_-_32290096 0.48 ENSDART00000148763
cpt1cb
carnitine palmitoyltransferase 1Cb
chr10_+_22034477 0.48 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
npm1a
nucleophosmin 1a
chr13_+_15702142 0.48 ENSDART00000135960
trmt61a
tRNA methyltransferase 61A
chr11_+_30636351 0.48 ENSDART00000087909
tmem246
transmembrane protein 246
chr23_-_31913069 0.48 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr22_-_16270462 0.47 ENSDART00000105681
cdc14ab
cell division cycle 14Ab
chr2_+_23613040 0.47 ENSDART00000026694
rpp40
ribonuclease P/MRP 40 subunit
chr14_+_46118834 0.47 ENSDART00000124417
ENSDART00000017785
naa15a
N(alpha)-acetyltransferase 15, NatA auxiliary subunit a
chr16_-_21668082 0.47 ENSDART00000088513
gnl1
guanine nucleotide binding protein-like 1
chr9_-_27391908 0.47 ENSDART00000135221
nepro
nucleolus and neural progenitor protein
chr3_+_42126062 0.47 ENSDART00000154052
mrm2
mitochondrial rRNA methyltransferase 2
chr12_+_17933775 0.47 ENSDART00000186047
ENSDART00000160586
trrap
transformation/transcription domain-associated protein
chr5_+_30596822 0.47 ENSDART00000188375
hinfp
histone H4 transcription factor
chr17_+_22760126 0.46 ENSDART00000151999
ENSDART00000190442
ttc27
tetratricopeptide repeat domain 27
chr14_+_35414632 0.46 ENSDART00000191516
ENSDART00000084914
trmt12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr9_-_11676491 0.46 ENSDART00000022358
zc3h15
zinc finger CCCH-type containing 15
chr24_+_21514283 0.46 ENSDART00000007066
cdk8
cyclin-dependent kinase 8
chr14_-_41369629 0.46 ENSDART00000173040
cstf2
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr16_-_26528140 0.46 ENSDART00000134448
ENSDART00000147062
l3mbtl1b
l(3)mbt-like 1b (Drosophila)
chr22_+_10713713 0.46 ENSDART00000122349
hiat1b
hippocampus abundant transcript 1b
chr22_-_28777374 0.46 ENSDART00000188206
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr20_+_46311707 0.46 ENSDART00000184743
flvcr2b
feline leukemia virus subgroup C cellular receptor family, member 2b
chr7_-_49801183 0.45 ENSDART00000052083
fjx1
four jointed box 1
chr20_-_7000225 0.45 ENSDART00000100098
adcy1a
adenylate cyclase 1a
chr9_-_11587070 0.45 ENSDART00000030995
umps
uridine monophosphate synthetase
chr3_+_33440615 0.45 ENSDART00000146005
gtpbp1
GTP binding protein 1
chr24_+_39518774 0.45 ENSDART00000132939
dcun1d3
defective in cullin neddylation 1 domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of mycn

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:1902102 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.5 1.5 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.4 4.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.4 1.8 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.3 0.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 1.1 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.3 1.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.3 0.8 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.2 1.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.2 1.3 GO:0030719 P granule organization(GO:0030719)
0.2 0.8 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.2 0.6 GO:0071042 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.2 0.8 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.2 0.5 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.2 1.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 1.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 0.6 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 2.0 GO:0009303 rRNA transcription(GO:0009303)
0.2 0.9 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.4 GO:0033212 iron assimilation(GO:0033212)
0.1 0.4 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 4.8 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.5 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.1 0.8 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.5 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 2.0 GO:0006265 DNA topological change(GO:0006265)
0.1 0.5 GO:0097037 heme export(GO:0097037)
0.1 0.4 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.5 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.1 0.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.6 GO:0045943 regulation of transcription from RNA polymerase I promoter(GO:0006356) positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.9 GO:0001510 RNA methylation(GO:0001510)
0.1 0.4 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.1 0.9 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.6 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.1 1.6 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.1 0.4 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 0.5 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.4 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.5 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.5 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.2 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.8 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.2 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 0.6 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.2 GO:0009595 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.1 0.6 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.1 0.2 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.0 GO:0000154 rRNA modification(GO:0000154)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.5 GO:0044211 CTP salvage(GO:0044211)
0.1 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 0.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.7 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 1.0 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 1.3 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 1.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0006788 heme oxidation(GO:0006788)
0.0 0.6 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.0 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.3 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.4 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 1.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.3 GO:0045117 azole transport(GO:0045117)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.5 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0006585 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.5 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.4 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 1.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.5 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.7 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.6 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 0.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:0006415 translational termination(GO:0006415)
0.0 0.4 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.7 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:0006400 tRNA modification(GO:0006400)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 1.8 GO:0007283 spermatogenesis(GO:0007283)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.5 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.5 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.0 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 1.1 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.8 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.3 GO:0006298 mismatch repair(GO:0006298)
0.0 0.8 GO:0006476 protein deacetylation(GO:0006476)
0.0 0.0 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.3 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.5 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.0 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.4 1.9 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.3 2.7 GO:0071546 pi-body(GO:0071546)
0.3 1.1 GO:0035339 SPOTS complex(GO:0035339)
0.3 0.8 GO:0032301 MutSalpha complex(GO:0032301)
0.2 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.2 0.9 GO:0031415 NatA complex(GO:0031415)
0.2 0.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 1.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.9 GO:0030681 ribonuclease MRP complex(GO:0000172) multimeric ribonuclease P complex(GO:0030681)
0.1 0.8 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.8 GO:0035517 PR-DUB complex(GO:0035517)
0.1 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.2 GO:0043186 P granule(GO:0043186)
0.1 0.5 GO:0000801 central element(GO:0000801)
0.1 0.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.4 GO:1902555 endoribonuclease complex(GO:1902555)
0.1 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.3 GO:0097268 cytoophidium(GO:0097268)
0.1 1.5 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.3 GO:0097255 R2TP complex(GO:0097255)
0.1 0.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 7.2 GO:0005730 nucleolus(GO:0005730)
0.0 0.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.0 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 2.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 1.1 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.1 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.3 0.8 GO:0032356 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.2 0.7 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 0.7 GO:0003913 DNA photolyase activity(GO:0003913)
0.2 0.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 1.7 GO:0034584 piRNA binding(GO:0034584)
0.2 0.9 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.2 3.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.5 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.2 2.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.6 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.1 1.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 0.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.5 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.1 1.0 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.3 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.3 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 2.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.7 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.6 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.2 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.8 GO:2001069 glycogen binding(GO:2001069)
0.0 1.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.6 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.9 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.7 GO:0031386 protein tag(GO:0031386)
0.0 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.3 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.3 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 1.6 GO:0000049 tRNA binding(GO:0000049)
0.0 1.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 2.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.6 GO:0008483 transaminase activity(GO:0008483)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.5 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.9 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 2.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 1.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.2 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.4 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones