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PRJNA195909:zebrafish embryo and larva development

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Results for neurod1

Z-value: 1.05

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Transcription factors associated with neurod1

Gene Symbol Gene ID Gene Info
neurod1
ENSDARG00000019566 neuronal differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
neurod1dr11_v1_chr9_-_44295071_442950710.304.3e-01Click!

Activity profile of neurod1 motif

Sorted Z-values of neurod1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_-_554142 0.84 ENSDART00000028997
myo9ab
myosin IXAb
chr3_-_50443607 0.61 ENSDART00000074036
rcvrna
recoverin a
chr11_-_28911172 0.57 ENSDART00000168493
igsf21a
immunoglobin superfamily, member 21a
chr9_-_1200187 0.56 ENSDART00000158760
ino80da
INO80 complex subunit Da
chr8_-_26609259 0.56 ENSDART00000027301
sema3b
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr1_+_21937201 0.55 ENSDART00000087729
kdm4c
lysine (K)-specific demethylase 4C
chr12_+_21525496 0.53 ENSDART00000152974
ca10a
carbonic anhydrase Xa
chr2_+_50626476 0.52 ENSDART00000018150
neurod6b
neuronal differentiation 6b
chr21_-_13085242 0.49 ENSDART00000044504
zgc:109965
zgc:109965
chr6_-_9565526 0.48 ENSDART00000151470
map3k2
mitogen-activated protein kinase kinase kinase 2
chr9_+_25096500 0.47 ENSDART00000135074
ENSDART00000180436
ENSDART00000108629
lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr5_+_62611400 0.46 ENSDART00000132054
abr
active BCR-related
chr7_+_29133321 0.46 ENSDART00000052346
gnao1b
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr24_-_1657276 0.45 ENSDART00000168131
si:ch73-378g22.1
si:ch73-378g22.1
chr6_-_13783604 0.41 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
cryba2a
crystallin, beta A2a
chr5_-_18513950 0.40 ENSDART00000145878
si:dkey-215k6.1
si:dkey-215k6.1
chr2_+_31475772 0.38 ENSDART00000130722
cacnb2b
calcium channel, voltage-dependent, beta 2b
chr9_-_44295071 0.37 ENSDART00000011837
neurod1
neuronal differentiation 1
chr2_+_7557912 0.37 ENSDART00000160053
ripk2
receptor-interacting serine-threonine kinase 2
chr5_-_19932621 0.36 ENSDART00000088881
git2a
G protein-coupled receptor kinase interacting ArfGAP 2a
chr16_-_33097398 0.36 ENSDART00000166617
dopey1
dopey family member 1
chr19_-_38872650 0.36 ENSDART00000146641
adgrb2
adhesion G protein-coupled receptor B2
chr18_+_46773198 0.35 ENSDART00000174647
CABZ01041495.1

chr16_-_29334672 0.35 ENSDART00000162835
bcan
brevican
chr17_-_25397558 0.35 ENSDART00000182052
fam167b
family with sequence similarity 167, member B
chr18_+_45550783 0.34 ENSDART00000138075
kifc3
kinesin family member C3
chr23_+_20563779 0.34 ENSDART00000146008
camkvl
CaM kinase-like vesicle-associated, like
chr3_-_21061931 0.33 ENSDART00000036741
fam57ba
family with sequence similarity 57, member Ba
chr3_-_21062706 0.33 ENSDART00000155605
ENSDART00000153686
ENSDART00000157168
ENSDART00000156614
ENSDART00000155743
ENSDART00000156275
fam57ba
family with sequence similarity 57, member Ba
chr5_+_11407504 0.32 ENSDART00000186723
ENSDART00000018047
zgc:112294
zgc:112294
chr3_-_60886984 0.32 ENSDART00000170974
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr7_-_48263516 0.32 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
rbpms2b
RNA binding protein with multiple splicing 2b
chr12_-_14922955 0.31 ENSDART00000002078
neurod2
neurogenic differentiation 2
chr9_-_22831836 0.31 ENSDART00000142585
neb
nebulin
chr23_+_5470967 0.31 ENSDART00000110522
ENSDART00000149050
tulp1a
tubby like protein 1a
chr11_+_30647545 0.31 ENSDART00000114792
gb:eh507706
expressed sequence EH507706
chr3_+_50069610 0.30 ENSDART00000056619
zgc:103625
zgc:103625
chr12_-_22238004 0.30 ENSDART00000038310
ormdl3
ORMDL sphingolipid biosynthesis regulator 3
chr12_+_23892972 0.30 ENSDART00000152852
svila
supervillin a
chr1_-_34450784 0.30 ENSDART00000140515
lmo7b
LIM domain 7b
chr12_-_41618844 0.30 ENSDART00000160054
dpysl4
dihydropyrimidinase-like 4
chr8_+_36500061 0.29 ENSDART00000185840
slc7a4
solute carrier family 7, member 4
chr6_+_18359306 0.29 ENSDART00000157796
cbx8b
chromobox homolog 8b
chr6_-_26225814 0.29 ENSDART00000089121
hs2st1b
heparan sulfate 2-O-sulfotransferase 1b
chr5_-_33769211 0.29 ENSDART00000133504
dab2ipb
DAB2 interacting protein b
chr13_-_7031033 0.29 ENSDART00000193211
CABZ01061524.1

chr5_+_36768674 0.29 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr19_-_10656667 0.29 ENSDART00000081379
ENSDART00000151456
ENSDART00000143271
ENSDART00000182126
olah
oleoyl-ACP hydrolase
chr16_-_29480335 0.28 ENSDART00000148930
lingo4b
leucine rich repeat and Ig domain containing 4b
chr21_+_6212844 0.28 ENSDART00000150301
fnbp1b
formin binding protein 1b
chr7_+_50828774 0.28 ENSDART00000182821
per1b
period circadian clock 1b
chr24_+_40905100 0.28 ENSDART00000167854
scn12ab
sodium channel, voltage gated, type XII, alpha b
chr19_-_38830582 0.27 ENSDART00000189966
ENSDART00000183055
adgrb2
adhesion G protein-coupled receptor B2
chr6_-_9563534 0.27 ENSDART00000184765
map3k2
mitogen-activated protein kinase kinase kinase 2
chr6_+_13787855 0.27 ENSDART00000182899
tmem198b
transmembrane protein 198b
chr1_-_40227166 0.27 ENSDART00000146680
si:ch211-113e8.3
si:ch211-113e8.3
chr19_-_32888758 0.27 ENSDART00000052080
laptm4b
lysosomal protein transmembrane 4 beta
chr12_-_41619257 0.27 ENSDART00000162967
dpysl4
dihydropyrimidinase-like 4
chr7_+_30823749 0.27 ENSDART00000085661
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr20_+_23498255 0.27 ENSDART00000149922
palld
palladin, cytoskeletal associated protein
chr2_-_32574944 0.27 ENSDART00000056642
tmub1
transmembrane and ubiquitin-like domain containing 1
chr12_+_46543572 0.26 ENSDART00000167510
hid1b
HID1 domain containing b
chr15_+_30158652 0.26 ENSDART00000190682
nlk2
nemo-like kinase, type 2
chr23_-_18057851 0.26 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
zgc:92287
chr5_-_40190949 0.26 ENSDART00000175588
wdfy3
WD repeat and FYVE domain containing 3
chr5_+_60919378 0.26 ENSDART00000184915
doc2b
double C2-like domains, beta
chr23_+_5465806 0.26 ENSDART00000149434
ENSDART00000148506
tulp1a
tubby like protein 1a
chr24_-_10828560 0.25 ENSDART00000132282
fam49bb
family with sequence similarity 49, member Bb
chr17_+_12075805 0.25 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr23_-_18057553 0.25 ENSDART00000173102
ENSDART00000058742
zgc:92287
zgc:92287
chr2_-_22230326 0.25 ENSDART00000127810
fam110b
family with sequence similarity 110, member B
chr24_-_17444067 0.25 ENSDART00000155843
cntnap2a
contactin associated protein like 2a
chr21_+_39100289 0.25 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr14_+_32838110 0.24 ENSDART00000158077
arr3b
arrestin 3b, retinal (X-arrestin)
chr19_-_5812319 0.24 ENSDART00000114472
si:ch211-264f5.8
si:ch211-264f5.8
chr20_-_44576949 0.24 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr20_-_18731268 0.24 ENSDART00000183893
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr21_-_16632808 0.24 ENSDART00000172645
unc5da
unc-5 netrin receptor Da
chr19_-_6134802 0.24 ENSDART00000140051
cica
capicua transcriptional repressor a
chr8_+_7359294 0.24 ENSDART00000121708
pcsk1nl
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr12_+_31744217 0.24 ENSDART00000190361
RNF157
si:dkey-49c17.3
chr7_+_39389273 0.24 ENSDART00000191298
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr7_+_55950229 0.23 ENSDART00000082780
ACSF3
acyl-CoA synthetase family member 3
chr24_+_32472155 0.23 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr2_+_5948534 0.23 ENSDART00000124324
ENSDART00000176461
slc1a7a
solute carrier family 1 (glutamate transporter), member 7a
chr10_+_15777258 0.23 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr18_+_29145681 0.23 ENSDART00000089031
ENSDART00000193336
ppfibp2a
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr6_-_35487413 0.23 ENSDART00000102461
rgs8
regulator of G protein signaling 8
chr18_-_12858016 0.23 ENSDART00000130343
parp12a
poly (ADP-ribose) polymerase family, member 12a
chr8_-_6943155 0.23 ENSDART00000139545
ENSDART00000033294
wdr13
WD repeat domain 13
chr14_+_32837914 0.23 ENSDART00000158888
arr3b
arrestin 3b, retinal (X-arrestin)
chr5_+_37854685 0.23 ENSDART00000051222
ENSDART00000185283
ins
preproinsulin
chr2_+_25198648 0.23 ENSDART00000110922
ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr5_-_26493253 0.23 ENSDART00000088222
arvcfb
ARVCF, delta catenin family member b
chr13_-_16257848 0.23 ENSDART00000079745
zgc:110045
zgc:110045
chr13_-_16226312 0.22 ENSDART00000163952
zgc:110045
zgc:110045
chr17_-_51829310 0.22 ENSDART00000154544
numb
numb homolog (Drosophila)
chr21_+_44300689 0.22 ENSDART00000186298
ENSDART00000142810
gabra3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr5_-_30145939 0.22 ENSDART00000086795
zbtb44
zinc finger and BTB domain containing 44
chr5_+_42912966 0.22 ENSDART00000039973
rufy3
RUN and FYVE domain containing 3
chr2_+_21309272 0.22 ENSDART00000141322
zbtb47a
zinc finger and BTB domain containing 47a
chr20_-_53963515 0.22 ENSDART00000110252
ppp2r5cb
protein phosphatase 2, regulatory subunit B', gamma b
chr24_-_34335265 0.22 ENSDART00000128690
agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr14_+_21722235 0.22 ENSDART00000183667
stx3a
syntaxin 3A
chr18_-_10995410 0.22 ENSDART00000136751
tspan33b
tetraspanin 33b
chr6_-_43449013 0.22 ENSDART00000122423
eevs
2-epi-5-epi-valiolone synthase
chr19_+_177455 0.22 ENSDART00000111580
tmem65
transmembrane protein 65
chr16_-_51151993 0.22 ENSDART00000156255
ago1
argonaute RISC catalytic component 1
chr13_-_44285793 0.22 ENSDART00000167383
CABZ01069436.1

chr19_-_25427255 0.21 ENSDART00000036854
glcci1a
glucocorticoid induced 1a
chr12_-_35949936 0.21 ENSDART00000192583
AL954682.1

chr19_+_43684376 0.21 ENSDART00000051723
si:ch211-193k19.1
si:ch211-193k19.1
chr15_-_28094256 0.21 ENSDART00000142041
ENSDART00000132153
ENSDART00000146657
ENSDART00000048720
cryba1a
crystallin, beta A1a
chr11_+_24925434 0.21 ENSDART00000131431
sulf2a
sulfatase 2a
chr16_-_35329803 0.21 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
ptprub
protein tyrosine phosphatase, receptor type, U, b
chr6_-_4214297 0.21 ENSDART00000191433
trak2
trafficking protein, kinesin binding 2
chr20_-_39273987 0.20 ENSDART00000127173
clu
clusterin
chr7_-_55292116 0.20 ENSDART00000122603
rnf166
ring finger protein 166
chr13_-_30027730 0.20 ENSDART00000044009
scdb
stearoyl-CoA desaturase b
chr5_-_40734045 0.20 ENSDART00000010896
isl1
ISL LIM homeobox 1
chr7_-_54217547 0.20 ENSDART00000162777
ENSDART00000188268
ENSDART00000165875
csnk1g1
casein kinase 1, gamma 1
chr1_+_18863060 0.20 ENSDART00000139241
rnf38
ring finger protein 38
chr17_-_36988455 0.20 ENSDART00000187180
ENSDART00000126823
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr8_-_16592491 0.20 ENSDART00000101655
calr
calreticulin
chr6_-_51101834 0.20 ENSDART00000092493
ptprt
protein tyrosine phosphatase, receptor type, t
chr25_+_33849647 0.20 ENSDART00000121449
roraa
RAR-related orphan receptor A, paralog a
chr19_+_49721 0.20 ENSDART00000160489
col14a1b
collagen, type XIV, alpha 1b
chr25_-_35664817 0.20 ENSDART00000148718
lrrk2
leucine-rich repeat kinase 2
chr22_+_24157807 0.20 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_-_29045426 0.20 ENSDART00000019770
gpm6ba
glycoprotein M6Ba
chr6_-_35032792 0.20 ENSDART00000168256
ddr2a
discoidin domain receptor tyrosine kinase 2a
chr12_-_33659328 0.20 ENSDART00000153457
tmem94
transmembrane protein 94
chr6_+_52804267 0.20 ENSDART00000065681
matn4
matrilin 4
chr24_+_14801844 0.19 ENSDART00000141620
pi15a
peptidase inhibitor 15a
chr21_+_8427059 0.19 ENSDART00000143151
dennd1a
DENN/MADD domain containing 1A
chr2_-_21352101 0.19 ENSDART00000057021
hhatla
hedgehog acyltransferase like, a
chr18_-_42313798 0.19 ENSDART00000098639
cntn5
contactin 5
chr12_+_32292564 0.19 ENSDART00000152945
ANKFN1
si:ch211-277e21.2
chr10_-_5847904 0.19 ENSDART00000161096
ankrd55
ankyrin repeat domain 55
chr19_+_33553586 0.19 ENSDART00000183477
runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_+_15777064 0.19 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr17_+_23146976 0.19 ENSDART00000114212
rasgrp3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr25_-_18948816 0.19 ENSDART00000091549
nt5dc3
5'-nucleotidase domain containing 3
chr19_-_868187 0.18 ENSDART00000186626
eomesa
eomesodermin homolog a
chr23_-_31647793 0.18 ENSDART00000145621
sgk1
serum/glucocorticoid regulated kinase 1
chr3_-_61494840 0.18 ENSDART00000101957
baiap2l1b
BAI1-associated protein 2-like 1b
chr6_+_22597362 0.18 ENSDART00000131242
cygb2
cytoglobin 2
chr20_+_6756247 0.18 ENSDART00000167344
igfbp3
insulin-like growth factor binding protein 3
chr23_-_18057270 0.18 ENSDART00000173385
zgc:92287
zgc:92287
chr6_+_9175886 0.18 ENSDART00000165333
si:ch211-207l14.1
si:ch211-207l14.1
chr10_+_31809226 0.18 ENSDART00000087898
foxo1b
forkhead box O1 b
chr8_-_50147948 0.18 ENSDART00000149010
hp
haptoglobin
chr20_+_48100261 0.18 ENSDART00000158604
xkr5a
XK related 5a
chr19_-_24136233 0.18 ENSDART00000143365
thap7
THAP domain containing 7
chr18_-_399554 0.18 ENSDART00000164374
ENSDART00000186311
ENSDART00000181816
ENSDART00000181892
si:ch211-79l17.1
si:ch211-79l17.1
chr1_-_14233815 0.18 ENSDART00000044896
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr3_-_36745935 0.18 ENSDART00000184853
abcc6b.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1
chr17_+_25397070 0.18 ENSDART00000164254
zgc:154055
zgc:154055
chr7_+_74134010 0.18 ENSDART00000164874
cldnd1a
claudin domain containing 1a
chr10_-_6867282 0.17 ENSDART00000144001
ENSDART00000109744
ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr8_+_25145464 0.17 ENSDART00000136505
gnai3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr10_+_29431529 0.17 ENSDART00000158154
dlg2
discs, large homolog 2 (Drosophila)
chr17_-_2535682 0.17 ENSDART00000155227
ccdc9b
coiled-coil domain containing 9B
chr17_-_51202339 0.17 ENSDART00000167117
si:ch1073-469d17.2
si:ch1073-469d17.2
chr13_+_8604710 0.17 ENSDART00000091097
socs5b
suppressor of cytokine signaling 5b
chr20_+_21268795 0.17 ENSDART00000090016
nudt14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr18_-_38087875 0.17 ENSDART00000111301
luzp2
leucine zipper protein 2
chr8_-_49935358 0.17 ENSDART00000159782
ENSDART00000156841
agtpbp1
CU694202.1
ATP/GTP binding protein 1

chr22_-_33679277 0.17 ENSDART00000169948
FO904977.1

chr4_-_1324141 0.17 ENSDART00000180720
ptn
pleiotrophin
chr7_+_26224211 0.17 ENSDART00000173999
vgf
VGF nerve growth factor inducible
chr15_-_20954552 0.17 ENSDART00000006910
tbcela
tubulin folding cofactor E-like a
chr5_-_51819027 0.17 ENSDART00000164267
homer1b
homer scaffolding protein 1b
chr9_+_49712868 0.17 ENSDART00000192969
ENSDART00000183310
CSRNP3
cysteine and serine rich nuclear protein 3
chr21_-_43527198 0.17 ENSDART00000126092
irs4a
insulin receptor substrate 4a
chr1_-_7893808 0.17 ENSDART00000110154
radil
Ras association and DIL domains
chr18_+_15795566 0.17 ENSDART00000099944
nudt4a
nudix (nucleoside diphosphate linked moiety X)-type motif 4a
chr23_-_27692717 0.17 ENSDART00000053878
ENSDART00000145028
IKZF4
si:dkey-166n8.9
chr3_+_36972298 0.17 ENSDART00000150917
si:ch211-18i17.2
si:ch211-18i17.2
chr23_+_25172682 0.17 ENSDART00000191197
ENSDART00000183497
si:dkey-151g10.3
si:dkey-151g10.3
chr11_+_6881001 0.16 ENSDART00000170331
klhl26
kelch-like family member 26
chr7_+_32722227 0.16 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr13_-_12667220 0.16 ENSDART00000079594
fam241a
family with sequence similarity 241 member A
chr15_-_7598294 0.16 ENSDART00000165898
gbe1b
glucan (1,4-alpha-), branching enzyme 1b
chr20_-_26001288 0.16 ENSDART00000136518
ENSDART00000063177
capn3b
calpain 3b
chr4_+_8376362 0.16 ENSDART00000138653
ENSDART00000132647
erc1b
ELKS/RAB6-interacting/CAST family member 1b
chr6_+_21095918 0.16 ENSDART00000167225
spega
SPEG complex locus a
chr7_-_58130703 0.16 ENSDART00000172082
ank2b
ankyrin 2b, neuronal
chr11_+_6902946 0.16 ENSDART00000144006
crtc1b
CREB regulated transcription coactivator 1b
chr11_+_37049347 0.16 ENSDART00000109235
bicd2
bicaudal D homolog 2 (Drosophila)
chr5_-_38342992 0.16 ENSDART00000140337
mink1
misshapen-like kinase 1
chr21_+_27382893 0.16 ENSDART00000005682
actn3a
actinin alpha 3a
chr21_+_13353263 0.16 ENSDART00000114677
si:ch73-62l21.1
si:ch73-62l21.1
chr2_-_31800521 0.16 ENSDART00000112763
retreg1
reticulophagy regulator 1
chr11_+_37049105 0.16 ENSDART00000155408
bicd2
bicaudal D homolog 2 (Drosophila)
chr20_+_1412193 0.16 ENSDART00000064419
leg1.1
liver-enriched gene 1, tandem duplicate 1
chr16_-_32013913 0.16 ENSDART00000030282
ENSDART00000138701
gstk1
glutathione S-transferase kappa 1
chr3_+_36972586 0.16 ENSDART00000102784
si:ch211-18i17.2
si:ch211-18i17.2
chr21_-_22737228 0.16 ENSDART00000151366
fbxo40.2
F-box protein 40, tandem duplicate 2
chr8_-_3716734 0.16 ENSDART00000172966
bicdl1
BICD family like cargo adaptor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of neurod1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.2 0.5 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.3 GO:0060074 synapse maturation(GO:0060074)
0.1 0.3 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.4 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.2 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.1 0.2 GO:0060262 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.1 0.3 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.3 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 0.2 GO:0030858 positive regulation of epithelial cell differentiation(GO:0030858) negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.1 0.6 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 0.2 GO:0097264 self proteolysis(GO:0097264)
0.1 0.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.2 GO:0006145 allantoin catabolic process(GO:0000256) purine nucleobase catabolic process(GO:0006145)
0.1 0.3 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.2 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.5 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.3 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.6 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) nucleobase catabolic process(GO:0046113)
0.0 0.1 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 0.4 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0003091 renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.1 GO:0044241 lipid digestion(GO:0044241)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0006921 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.3 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.6 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.4 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.4 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.2 GO:0061709 reticulophagy(GO:0061709)
0.0 0.2 GO:1990402 embryonic liver development(GO:1990402)
0.0 0.1 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0055062 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.0 0.7 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.0 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.0 0.0 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.0 0.1 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.1 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.4 GO:1903039 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.8 GO:0030426 growth cone(GO:0030426)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.0 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 0.5 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.1 0.5 GO:0034452 dynactin binding(GO:0034452)
0.1 0.2 GO:0032896 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.3 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.0 0.1 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.2 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0009384 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0008887 glycerate kinase activity(GO:0008887)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.3 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors