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PRJNA195909:zebrafish embryo and larva development

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Results for nfe2l2a

Z-value: 1.48

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Transcription factors associated with nfe2l2a

Gene Symbol Gene ID Gene Info
nfe2l2a
ENSDARG00000042824 nuclear factor, erythroid 2-like 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfe2l2adr11_v1_chr9_+_1654284_16542840.964.0e-05Click!

Activity profile of nfe2l2a motif

Sorted Z-values of nfe2l2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_67471375 4.52 ENSDART00000147009
si:dkey-251i10.2
si:dkey-251i10.2
chr3_-_26017592 3.91 ENSDART00000030890
hmox1a
heme oxygenase 1a
chr3_-_26017831 3.88 ENSDART00000179982
hmox1a
heme oxygenase 1a
chr3_-_55139127 3.64 ENSDART00000115324
hbae1.3
hemoglobin, alpha embryonic 1.3
chr9_-_22076368 3.22 ENSDART00000128486
crygm2a
crystallin, gamma M2a
chr19_-_7450796 3.13 ENSDART00000104750
mllt11
MLLT11, transcription factor 7 cofactor
chr5_-_30615901 3.01 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr19_-_30404096 2.64 ENSDART00000103475
agr2
anterior gradient 2
chr21_+_20383837 2.23 ENSDART00000026430
hspb11
heat shock protein, alpha-crystallin-related, b11
chr22_-_26595027 2.18 ENSDART00000184162
CABZ01072309.1

chr19_+_48176745 2.13 ENSDART00000164963
prdm1b
PR domain containing 1b, with ZNF domain
chr19_-_30403922 2.11 ENSDART00000181841
agr2
anterior gradient 2
chr7_+_38750871 2.07 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
f2
coagulation factor II (thrombin)
chr14_+_34780886 1.84 ENSDART00000130469
ENSDART00000188806
ENSDART00000172924
ENSDART00000173266
ENSDART00000166377
ENSDART00000173371
sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr14_+_11457500 1.81 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr11_+_2198831 1.78 ENSDART00000160515
hoxc6b
homeobox C6b
chr19_-_6385594 1.68 ENSDART00000104950
atp1a3a
ATPase Na+/K+ transporting subunit alpha 3a
chr13_+_28903959 1.64 ENSDART00000166435
si:ch73-28h20.1
si:ch73-28h20.1
chr13_-_23007813 1.62 ENSDART00000057638
hk1
hexokinase 1
chr11_-_24681292 1.62 ENSDART00000089601
olfml3b
olfactomedin-like 3b
chr3_+_23669267 1.55 ENSDART00000111227
hoxb10a
homeobox B10a
chr20_-_39103119 1.48 ENSDART00000143379
rcan2
regulator of calcineurin 2
chr9_+_41103127 1.44 ENSDART00000000250
slc40a1
solute carrier family 40 (iron-regulated transporter), member 1
chr12_+_48216662 1.34 ENSDART00000187369
lrrc20
leucine rich repeat containing 20
chr7_-_15413019 1.29 ENSDART00000172147
si:ch211-106j24.1
si:ch211-106j24.1
chr13_-_21688176 1.26 ENSDART00000063825
sprn
shadow of prion protein
chr3_-_21280373 1.24 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr10_-_7974155 1.24 ENSDART00000147368
ENSDART00000075524
osbp2
oxysterol binding protein 2
chr11_-_25418856 1.23 ENSDART00000013714
gata1a
GATA binding protein 1a
chr11_-_3334248 1.18 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr5_-_40297003 1.13 ENSDART00000097526
hspb3
heat shock protein, alpha-crystallin-related, b3
chr11_+_26609110 1.12 ENSDART00000042322
map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr5_-_64823750 1.11 ENSDART00000140305
lix1
limb and CNS expressed 1
chr14_-_17588345 1.10 ENSDART00000143486
selenot2
selenoprotein T, 2
chr12_-_1951233 1.09 ENSDART00000005676
ENSDART00000127937
sox9a
SRY (sex determining region Y)-box 9a
chr14_-_25985698 1.09 ENSDART00000172909
ENSDART00000123053
atox1
antioxidant 1 copper chaperone
chr7_-_39552314 1.06 ENSDART00000134174
slc22a18
solute carrier family 22, member 18
chr5_-_44843738 1.00 ENSDART00000003926
fbp1a
fructose-1,6-bisphosphatase 1a
chr10_+_29265463 0.99 ENSDART00000155390
crebzf
CREB/ATF bZIP transcription factor
chr24_-_24146875 0.98 ENSDART00000173052
map7d2b
MAP7 domain containing 2b
chr1_-_40227166 0.97 ENSDART00000146680
si:ch211-113e8.3
si:ch211-113e8.3
chr25_+_34581494 0.96 ENSDART00000167690
trpm1b
transient receptor potential cation channel, subfamily M, member 1b
chr22_-_31059670 0.94 ENSDART00000022445
cand2
cullin-associated and neddylation-dissociated 2 (putative)
chr21_+_45819662 0.94 ENSDART00000193362
ENSDART00000184255
pitx1
paired-like homeodomain 1
chr7_+_63325819 0.94 ENSDART00000085612
ENSDART00000161436
pcdh7b
protocadherin 7b
chr7_-_32833153 0.94 ENSDART00000099871
ENSDART00000099872
slc17a6b
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr1_-_5745420 0.93 ENSDART00000166779
nrp2a
neuropilin 2a
chr20_-_39271844 0.93 ENSDART00000192708
clu
clusterin
chr6_-_55958705 0.92 ENSDART00000155963
eya2
EYA transcriptional coactivator and phosphatase 2
chr6_-_35446110 0.92 ENSDART00000058773
rgs16
regulator of G protein signaling 16
chr4_-_16334362 0.89 ENSDART00000101461
epyc
epiphycan
chr14_+_30279391 0.87 ENSDART00000172794
fgl1
fibrinogen-like 1
chr22_-_13857729 0.86 ENSDART00000177971
s100b
S100 calcium binding protein, beta (neural)
chr17_+_45106424 0.86 ENSDART00000157338
ENSDART00000155104
GSTZ1
zgc:163014
chr13_+_35746440 0.85 ENSDART00000187859
gpr75
G protein-coupled receptor 75
chr19_+_8506178 0.84 ENSDART00000189689
s100a10a
S100 calcium binding protein A10a
chr21_+_5993188 0.83 ENSDART00000048399
slc4a4b
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr8_-_34051548 0.83 ENSDART00000105204
pbx3b
pre-B-cell leukemia homeobox 3b
chr8_-_34052019 0.83 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr9_-_23253870 0.81 ENSDART00000143657
ENSDART00000169911
acmsd
aminocarboxymuconate semialdehyde decarboxylase
chr1_+_52398205 0.81 ENSDART00000143225
si:ch211-217k17.9
si:ch211-217k17.9
chr7_+_57109214 0.80 ENSDART00000135068
ENSDART00000098412
enosf1
enolase superfamily member 1
chr19_-_17658160 0.78 ENSDART00000151766
ENSDART00000170790
ENSDART00000186678
ENSDART00000188045
ENSDART00000176980
ENSDART00000166313
ENSDART00000188589
thrb
thyroid hormone receptor beta
chr21_-_41025340 0.77 ENSDART00000148231
plac8l1
PLAC8-like 1
chr23_-_29376859 0.76 ENSDART00000146411
sst6
somatostatin 6
chr24_+_41940299 0.75 ENSDART00000022349
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr7_-_39551913 0.75 ENSDART00000173498
ENSDART00000143040
slc22a18
solute carrier family 22, member 18
chr17_-_17948587 0.75 ENSDART00000090447
hhipl1
HHIP-like 1
chr14_-_17072736 0.74 ENSDART00000106333
phox2bb
paired-like homeobox 2bb
chr24_-_16917086 0.74 ENSDART00000110715
cmbl
carboxymethylenebutenolidase homolog (Pseudomonas)
chr20_-_16906623 0.73 ENSDART00000012859
ENSDART00000171628
psma6b
proteasome subunit alpha 6b
chr15_+_37559570 0.71 ENSDART00000085522
hspb6
heat shock protein, alpha-crystallin-related, b6
chr16_+_13855039 0.70 ENSDART00000113764
ENSDART00000143983
zgc:174888
zgc:174888
chr22_-_10354381 0.69 ENSDART00000092050
stab1
stabilin 1
chr17_+_27176243 0.68 ENSDART00000162527
si:ch211-160f23.7
si:ch211-160f23.7
chr20_-_48604621 0.67 ENSDART00000161769
ENSDART00000157871
mgst3a
microsomal glutathione S-transferase 3a
chr7_-_15413188 0.66 ENSDART00000185980
si:ch211-106j24.1
si:ch211-106j24.1
chr16_-_27640995 0.66 ENSDART00000019658
nacad
NAC alpha domain containing
chr9_+_11202552 0.65 ENSDART00000151931
asic4a
acid-sensing (proton-gated) ion channel family member 4a
chr16_-_30880236 0.64 ENSDART00000035583
dennd3b
DENN/MADD domain containing 3b
chr11_-_29936755 0.64 ENSDART00000145251
pir
pirin
chr5_-_71460556 0.63 ENSDART00000108804
brinp1
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr21_+_9576176 0.62 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mapk10
mitogen-activated protein kinase 10
chr24_+_25259154 0.61 ENSDART00000171125
gabrr3b
gamma-aminobutyric acid (GABA) A receptor, rho 3b
chr23_+_3731375 0.60 ENSDART00000141782
smim29
small integral membrane protein 29
chr4_+_25630555 0.60 ENSDART00000133425
acot15
acyl-CoA thioesterase 15
chr2_-_6115688 0.60 ENSDART00000081663
prdx1
peroxiredoxin 1
chr20_-_48604199 0.60 ENSDART00000161762
ENSDART00000170894
mgst3a
microsomal glutathione S-transferase 3a
chr20_+_38724575 0.60 ENSDART00000015095
ENSDART00000152972
uts1
urotensin 1
chr24_+_18299175 0.59 ENSDART00000140994
tpk1
thiamin pyrophosphokinase 1
chr16_-_17162485 0.59 ENSDART00000123011
iffo1b
intermediate filament family orphan 1b
chr18_-_19405616 0.59 ENSDART00000191290
ENSDART00000090855
megf11
multiple EGF-like-domains 11
chr10_-_4375190 0.59 ENSDART00000016102
CABZ01073795.1

chr4_+_13696537 0.59 ENSDART00000109195
ENSDART00000122041
ENSDART00000192554
nrcama
neuronal cell adhesion molecule a
chr2_+_9821757 0.59 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
anxa13l
annexin A13, like
chr24_+_18299506 0.58 ENSDART00000172056
tpk1
thiamin pyrophosphokinase 1
chr11_+_10548171 0.57 ENSDART00000191497
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr7_+_756942 0.57 ENSDART00000152224
zgc:63470
zgc:63470
chr14_-_30960470 0.56 ENSDART00000129989
si:ch211-191o15.6
si:ch211-191o15.6
chr23_-_18286822 0.55 ENSDART00000136672
fam19a1a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1a
chr2_+_25278107 0.55 ENSDART00000131977
ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr7_+_62004048 0.54 ENSDART00000181818
smim20
small integral membrane protein 20
chr19_+_31404686 0.54 ENSDART00000078459
pip4p2
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
chr10_+_26747755 0.54 ENSDART00000100329
f9b
coagulation factor IXb
chr6_+_43903209 0.54 ENSDART00000006435
gpr27
G protein-coupled receptor 27
chr17_-_29902187 0.54 ENSDART00000009104
esrrb
estrogen-related receptor beta
chr2_-_6115389 0.53 ENSDART00000134921
prdx1
peroxiredoxin 1
chr10_+_10788811 0.53 ENSDART00000101077
ENSDART00000139143
ptgdsa
prostaglandin D2 synthase a
chr22_+_19640309 0.52 ENSDART00000061725
ENSDART00000140819
rgmd
RGM domain family, member D
chr21_-_39327223 0.52 ENSDART00000115097
aifm5
apoptosis-inducing factor, mitochondrion-associated, 5
chr5_+_65946222 0.51 ENSDART00000190969
ENSDART00000161578
mymk
myomaker, myoblast fusion factor
chr3_+_26064091 0.51 ENSDART00000143697
si:dkeyp-69e1.8
si:dkeyp-69e1.8
chr8_-_50259448 0.51 ENSDART00000146056
nkx3-1
NK3 homeobox 1
chr14_-_34771371 0.50 ENSDART00000160598
ENSDART00000150413
ENSDART00000168910
ablim3
actin binding LIM protein family, member 3
chr7_+_38936132 0.49 ENSDART00000173945
creb3l1
cAMP responsive element binding protein 3-like 1
chr19_-_7420867 0.49 ENSDART00000081741
rab25a
RAB25, member RAS oncogene family a
chr19_+_26828502 0.48 ENSDART00000183654
ENSDART00000126006
ENSDART00000185341
FP085398.1

chr11_-_23501467 0.47 ENSDART00000169066
plekha6
pleckstrin homology domain containing, family A member 6
chr20_-_1314537 0.46 ENSDART00000144288
pcmt
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr19_-_32600823 0.46 ENSDART00000134149
ENSDART00000187858
zgc:91944
zgc:91944
chr18_-_5692292 0.46 ENSDART00000121503
cplx3b
complexin 3b
chr7_-_52842605 0.46 ENSDART00000083002
map1aa
microtubule-associated protein 1Aa
chr21_-_5393125 0.45 ENSDART00000146061
psmd5
proteasome 26S subunit, non-ATPase 5
chr21_-_11820379 0.44 ENSDART00000126640
RHOBTB3
si:dkey-6b12.5
chr15_-_39820491 0.44 ENSDART00000097134
robo1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr22_-_26323893 0.44 ENSDART00000105099
capn1b
calpain 1, (mu/I) large subunit b
chr5_-_65262260 0.43 ENSDART00000167886
col27a1b
collagen, type XXVII, alpha 1b
chr20_-_16972351 0.41 ENSDART00000148312
ENSDART00000186702
si:ch73-74h11.1
si:ch73-74h11.1
chr3_+_36160979 0.41 ENSDART00000038525
si:ch211-234h8.7
si:ch211-234h8.7
chr14_-_30490465 0.40 ENSDART00000173107
micu3b
mitochondrial calcium uptake family, member 3b
chr8_+_29963024 0.40 ENSDART00000149372
ptch1
patched 1
chr5_-_54495678 0.40 ENSDART00000181970
alad
aminolevulinate dehydratase
chr7_+_17992640 0.40 ENSDART00000173679
ehbp1l1a
EH domain binding protein 1-like 1a
chr14_-_38873095 0.39 ENSDART00000047050
ENSDART00000173285
ENSDART00000147521
gsr
glutathione reductase
chr18_+_24922125 0.39 ENSDART00000180385
rgma
repulsive guidance molecule family member a
chr7_-_30127082 0.38 ENSDART00000173749
alpk3b
alpha-kinase 3b
chr14_-_32884138 0.37 ENSDART00000105726
slc25a5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr2_-_3038904 0.37 ENSDART00000186795
guk1a
guanylate kinase 1a
chr1_-_52498146 0.36 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr3_+_17846890 0.36 ENSDART00000193384
znf385c
zinc finger protein 385C
chr20_-_1314355 0.36 ENSDART00000152436
pcmt
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr19_-_41404870 0.35 ENSDART00000167772
sem1
SEM1, 26S proteasome complex subunit
chr5_-_54424019 0.35 ENSDART00000169270
ENSDART00000164067
coq4
coenzyme Q4 homolog (S. cerevisiae)
chr2_+_9822319 0.35 ENSDART00000144078
ENSDART00000144371
anxa13l
annexin A13, like
chr21_-_40782393 0.35 ENSDART00000075808
apbb3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr6_-_31364475 0.34 ENSDART00000145715
ENSDART00000134370
ak4
adenylate kinase 4
chr12_+_20587179 0.34 ENSDART00000170127
arsg
arylsulfatase G
chr24_+_25258904 0.33 ENSDART00000155714
gabrr3b
gamma-aminobutyric acid (GABA) A receptor, rho 3b
chr16_+_11029762 0.33 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr1_+_41609676 0.32 ENSDART00000183675
mogs
mannosyl-oligosaccharide glucosidase
chr23_+_19558574 0.32 ENSDART00000137811
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr12_+_5209822 0.32 ENSDART00000152610
SLC35G1
si:ch211-197g18.2
chr11_-_25775447 0.31 ENSDART00000161301
plch2b
phospholipase C, eta 2b
chr20_-_8443425 0.31 ENSDART00000083908
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr18_-_46763170 0.31 ENSDART00000171880
dner
delta/notch-like EGF repeat containing
chr9_+_28688574 0.31 ENSDART00000101319
zgc:162396
zgc:162396
chr24_+_24923166 0.30 ENSDART00000065288
pcyt1ba
phosphate cytidylyltransferase 1, choline, beta a
chr6_+_20651398 0.29 ENSDART00000183663
slc19a1
solute carrier family 19 (folate transporter), member 1
chr23_+_9560797 0.29 ENSDART00000180014
adrm1
adhesion regulating molecule 1
chr25_+_32474031 0.29 ENSDART00000152124
sqor
sulfide quinone oxidoreductase
chr25_+_10485103 0.29 ENSDART00000104576
psmd13
proteasome 26S subunit, non-ATPase 13
chr13_+_24519175 0.28 ENSDART00000190790
sertad2b
SERTA domain containing 2b
chr7_-_25697285 0.28 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr4_+_6572364 0.28 ENSDART00000122574
ppp1r3aa
protein phosphatase 1, regulatory subunit 3Aa
chr14_-_30490763 0.28 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
micu3b
mitochondrial calcium uptake family, member 3b
chr23_+_9560991 0.28 ENSDART00000081433
ENSDART00000131594
ENSDART00000130069
ENSDART00000138601
adrm1
adhesion regulating molecule 1
chr1_+_17376922 0.26 ENSDART00000145068
fat1a
FAT atypical cadherin 1a
chr21_+_25092300 0.26 ENSDART00000168505
dixdc1b
DIX domain containing 1b
chr1_+_9994811 0.25 ENSDART00000143719
ENSDART00000110749
si:dkeyp-75b4.10
si:dkeyp-75b4.10
chr17_-_23673864 0.25 ENSDART00000104738
ENSDART00000128958
ptena
phosphatase and tensin homolog A
chr13_-_17723417 0.24 ENSDART00000183834
vdac2
voltage-dependent anion channel 2
chr7_-_2116512 0.23 ENSDART00000098148
si:cabz01007802.1
si:cabz01007802.1
chr9_-_33749556 0.23 ENSDART00000149383
ndp
Norrie disease (pseudoglioma)
chr8_-_38403018 0.23 ENSDART00000134100
sorbs3
sorbin and SH3 domain containing 3
chr22_-_18116635 0.21 ENSDART00000005724
ncanb
neurocan b
chr10_+_38775408 0.21 ENSDART00000125045
dscama
Down syndrome cell adhesion molecule a
chr24_+_26039464 0.21 ENSDART00000131017
tnk2a
tyrosine kinase, non-receptor, 2a
chr11_+_13528437 0.20 ENSDART00000011362
arrdc2
arrestin domain containing 2
chr23_+_26142807 0.20 ENSDART00000158878
ptpn22
protein tyrosine phosphatase, non-receptor type 22
chr24_-_29868151 0.20 ENSDART00000184802
aglb
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr17_-_12966907 0.19 ENSDART00000022874
psma6a
proteasome subunit alpha 6a
chr17_-_23674065 0.17 ENSDART00000104735
ENSDART00000182952
ptena
phosphatase and tensin homolog A
chr2_+_37134281 0.17 ENSDART00000020135
pex19
peroxisomal biogenesis factor 19
chr11_+_21096339 0.17 ENSDART00000124574
il19l
interleukin 19 like
chr5_-_50640171 0.17 ENSDART00000183353
mctp1a
multiple C2 domains, transmembrane 1a
chr19_+_43119698 0.16 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr14_-_38872536 0.16 ENSDART00000184315
ENSDART00000127479
gsr
glutathione reductase
chr24_+_35911020 0.16 ENSDART00000088480
abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr24_+_24086249 0.15 ENSDART00000002953
lipib
lipase, member Ib
chr24_+_24086491 0.15 ENSDART00000145092
lipib
lipase, member Ib
chr14_-_2004291 0.15 ENSDART00000114039
pcdh2g5
protocadherin 2 gamma 5
chr25_-_16818978 0.14 ENSDART00000104140
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr22_-_557965 0.13 ENSDART00000001201
bysl
bystin-like
chr14_+_16093889 0.13 ENSDART00000159181
immt
inner membrane protein, mitochondrial (mitofilin)
chr22_+_558287 0.13 ENSDART00000189725
med20
mediator complex subunit 20
chr15_-_8191841 0.13 ENSDART00000156663
bach1a
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
chr3_+_43374571 0.12 ENSDART00000182497
zfand2a
zinc finger, AN1-type domain 2A
chr16_+_51326237 0.11 ENSDART00000168525
CU469384.1

chr13_+_7241170 0.11 ENSDART00000109434
aifm2
apoptosis-inducing factor, mitochondrion-associated, 2
chr9_+_19304697 0.11 ENSDART00000040449
htr1fa
5-hydroxytryptamine (serotonin) receptor 1Fa

Network of associatons between targets according to the STRING database.

First level regulatory network of nfe2l2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.6 3.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.5 4.8 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.5 1.9 GO:0030224 monocyte differentiation(GO:0030224)
0.4 1.2 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.4 1.4 GO:0010039 response to iron ion(GO:0010039)
0.3 2.1 GO:0006953 acute-phase response(GO:0006953)
0.3 1.0 GO:0005986 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.3 0.9 GO:0010265 SCF complex assembly(GO:0010265)
0.2 0.7 GO:0061549 sympathetic ganglion development(GO:0061549)
0.2 0.8 GO:0046551 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.2 4.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 0.7 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 1.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 0.8 GO:0046874 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.1 0.5 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.1 0.9 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 1.7 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.6 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.1 0.3 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.1 0.9 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.3 GO:0098838 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 2.2 GO:0031033 myosin filament organization(GO:0031033)
0.1 0.3 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.4 GO:0051503 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 1.7 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.4 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.1 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 0.3 GO:0042117 plasma membrane repair(GO:0001778) monocyte activation(GO:0042117)
0.1 2.2 GO:0097352 autophagosome maturation(GO:0097352)
0.1 0.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.4 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.1 0.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.0 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.8 GO:0051963 regulation of synapse assembly(GO:0051963)
0.0 0.3 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.2 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.9 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 1.2 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.4 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 1.9 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.5 GO:0042593 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.9 GO:0050868 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.4 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.5 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 2.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.5 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 1.0 GO:0060401 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.0 0.9 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.6 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0045454 cell redox homeostasis(GO:0045454)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.9 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.9 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.7 GO:1990246 uniplex complex(GO:1990246)
0.1 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 1.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0046930 pore complex(GO:0046930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.4 1.2 GO:0030975 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.3 1.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.3 3.6 GO:0031720 haptoglobin binding(GO:0031720)
0.3 1.6 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.1 GO:0016531 copper chaperone activity(GO:0016531)
0.2 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.6 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 1.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 1.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 1.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.8 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 1.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.5 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 0.4 GO:0051800 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.4 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.3 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 0.3 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.9 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.5 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.9 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.3 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 3.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.3 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 1.1 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.6 GO:0016790 thiolester hydrolase activity(GO:0016790)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 2.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.4 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 0.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction