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PRJNA195909:zebrafish embryo and larva development

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Results for nfil3-4+si:dkey-172o19.2

Z-value: 0.54

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Transcription factors associated with nfil3-4+si:dkey-172o19.2

Gene Symbol Gene ID Gene Info
si_dkey-172o19.2
ENSDARG00000071398 si_dkey-172o19.2
nfil3-4
ENSDARG00000092346 nuclear factor, interleukin 3 regulated, member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:dkey-172o19.2dr11_v1_chr22_+_20546612_20546612-0.274.8e-01Click!
nfil3-4dr11_v1_chr22_+_20560041_205600410.001.0e+00Click!

Activity profile of nfil3-4+si:dkey-172o19.2 motif

Sorted Z-values of nfil3-4+si:dkey-172o19.2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_12725513 0.63 ENSDART00000132286
mgst1.2
microsomal glutathione S-transferase 1.2
chr13_+_502230 0.60 ENSDART00000013007
degs1
delta(4)-desaturase, sphingolipid 1
chr23_-_23401305 0.56 ENSDART00000078936
her9
hairy-related 9
chr25_-_29415369 0.56 ENSDART00000110774
ENSDART00000019183
ugt5a2
ugt5a1
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr15_+_19838458 0.50 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr20_-_35246150 0.48 ENSDART00000090549
fzd3a
frizzled class receptor 3a
chr7_-_24364536 0.48 ENSDART00000064789
txn
thioredoxin
chr5_+_6955900 0.47 ENSDART00000099417
CABZ01041962.1

chr9_-_45602978 0.44 ENSDART00000139019
ENSDART00000085763
agr1
anterior gradient 1
chr8_+_2487883 0.43 ENSDART00000101841
dynll1
dynein, light chain, LC8-type 1
chr18_-_16922905 0.43 ENSDART00000187165
wee1
WEE1 G2 checkpoint kinase
chr25_+_24616717 0.42 ENSDART00000089113
abtb2b
ankyrin repeat and BTB (POZ) domain containing 2b
chr22_+_11775269 0.41 ENSDART00000140272
krt96
keratin 96
chr19_+_11985572 0.41 ENSDART00000130537
spag1a
sperm associated antigen 1a
chr5_+_26121393 0.39 ENSDART00000002221
bco2l
beta-carotene 15, 15-dioxygenase 2, like
chr20_+_1272526 0.38 ENSDART00000008115
ENSDART00000133825
hsd3b2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr13_+_18533005 0.37 ENSDART00000136024
ftr14l
finTRIM family, member 14-like
chr5_+_37091626 0.36 ENSDART00000161054
tagln2
transgelin 2
chr12_+_5708400 0.35 ENSDART00000017191
dlx3b
distal-less homeobox 3b
chr16_+_43139504 0.35 ENSDART00000065643
dbf4
DBF4 zinc finger
chr2_+_11685742 0.34 ENSDART00000138562
greb1l
growth regulation by estrogen in breast cancer-like
chr7_+_56577906 0.34 ENSDART00000184023
hp
haptoglobin
chr3_+_28594713 0.34 ENSDART00000179799
sept12
septin 12
chr14_+_21107032 0.34 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldob
aldolase b, fructose-bisphosphate
chr9_-_48736388 0.34 ENSDART00000022074
dhrs9
dehydrogenase/reductase (SDR family) member 9
chr7_+_56577522 0.33 ENSDART00000149130
ENSDART00000149624
hp
haptoglobin
chr14_-_12071679 0.33 ENSDART00000165581
tmsb1
thymosin beta 1
chr8_+_999421 0.32 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr14_+_21106444 0.32 ENSDART00000075744
ENSDART00000132363
aldob
aldolase b, fructose-bisphosphate
chr12_-_20584413 0.32 ENSDART00000170923
FP885542.2

chr17_-_14876758 0.31 ENSDART00000155857
nid2a
nidogen 2a (osteonidogen)
chr5_-_65037525 0.31 ENSDART00000158856
anxa1b
annexin A1b
chr11_-_8167799 0.31 ENSDART00000133574
ENSDART00000024046
ENSDART00000146940
uox
urate oxidase
chr5_-_65037371 0.31 ENSDART00000170560
anxa1b
annexin A1b
chr21_-_37194365 0.30 ENSDART00000100286
fgfr4
fibroblast growth factor receptor 4
chr10_-_20523405 0.30 ENSDART00000114824
ddhd2
DDHD domain containing 2
chr14_-_12071447 0.30 ENSDART00000166116
tmsb1
thymosin beta 1
chr1_-_35928942 0.30 ENSDART00000033566
smad1
SMAD family member 1
chr4_-_77432218 0.30 ENSDART00000158683
slco1d1
solute carrier organic anion transporter family, member 1D1
chr9_-_9225980 0.30 ENSDART00000180301
cbsb
cystathionine-beta-synthase b
chr12_+_31616412 0.30 ENSDART00000124439
cpn1
carboxypeptidase N, polypeptide 1
chr3_-_10312232 0.29 ENSDART00000081766
nog1
noggin 1
chr24_+_38671054 0.29 ENSDART00000154214
si:ch73-70c5.1
si:ch73-70c5.1
chr20_-_30900947 0.29 ENSDART00000153419
ENSDART00000062536
hebp2
heme binding protein 2
chr15_-_26636826 0.29 ENSDART00000087632
slc47a4
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr14_+_45406299 0.29 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr16_+_23984755 0.28 ENSDART00000145328
apoc2
apolipoprotein C-II
chr10_+_38526496 0.27 ENSDART00000144329
acer3
alkaline ceramidase 3
chr10_+_2799285 0.27 ENSDART00000030709
pnx
posterior neuron-specific homeobox
chr4_-_2545310 0.26 ENSDART00000150619
ENSDART00000140760
e2f7
E2F transcription factor 7
chr5_-_69212184 0.26 ENSDART00000053963
mat2ab
methionine adenosyltransferase II, alpha b
chr14_+_1170968 0.26 ENSDART00000125203
ENSDART00000193575
hopx
HOP homeobox
chr3_+_23092762 0.26 ENSDART00000142884
ENSDART00000024136
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr5_-_55560937 0.26 ENSDART00000148436
gna14
guanine nucleotide binding protein (G protein), alpha 14
chr15_-_29388012 0.26 ENSDART00000115032
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr21_+_25625026 0.26 ENSDART00000134678
ovol1b
ovo-like zinc finger 1b
chr15_-_29348212 0.26 ENSDART00000133117
tsku
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr20_+_25563105 0.25 ENSDART00000063100
cyp2p6
cytochrome P450, family 2, subfamily P, polypeptide 6
chr16_+_40576679 0.25 ENSDART00000169412
ENSDART00000193464
ccne2
cyclin E2
chr2_+_47905735 0.25 ENSDART00000159701
ftr23
finTRIM family, member 23
chr8_+_41647539 0.25 ENSDART00000136492
ENSDART00000138799
ENSDART00000134404
si:ch211-158d24.4
si:ch211-158d24.4
chr16_-_51253925 0.25 ENSDART00000050644
serpinb14
serpin peptidase inhibitor, clade B (ovalbumin), member 14
chr1_-_35929143 0.25 ENSDART00000185002
smad1
SMAD family member 1
chr20_-_9760424 0.25 ENSDART00000104936
si:dkey-63j12.4
si:dkey-63j12.4
chr16_-_30584279 0.24 ENSDART00000077226
mc5rb
melanocortin 5b receptor
chr9_-_456541 0.24 ENSDART00000159596
zgc:91849
zgc:91849
chr5_+_61476014 0.24 ENSDART00000050906
lrwd1
leucine-rich repeats and WD repeat domain containing 1
chr12_-_45197038 0.24 ENSDART00000016635
bccip
BRCA2 and CDKN1A interacting protein
chr5_+_61475451 0.24 ENSDART00000163444
lrwd1
leucine-rich repeats and WD repeat domain containing 1
chr24_-_26310854 0.24 ENSDART00000080113
apodb
apolipoprotein Db
chr19_+_16015881 0.23 ENSDART00000187135
ctps1a
CTP synthase 1a
chr1_-_39895859 0.23 ENSDART00000135791
ENSDART00000035739
tmem134
transmembrane protein 134
chr19_-_2231146 0.23 ENSDART00000181909
ENSDART00000043595
twist1a
twist family bHLH transcription factor 1a
chr4_+_30775376 0.23 ENSDART00000158528
si:dkey-11d20.1
si:dkey-11d20.1
chr5_-_57655092 0.23 ENSDART00000074290
mia
melanoma inhibitory activity
chr22_+_13886821 0.23 ENSDART00000130585
ENSDART00000105711
sh3bp4a
SH3-domain binding protein 4a
chr18_+_16943911 0.23 ENSDART00000157609
si:dkey-8l13.5
si:dkey-8l13.5
chr18_-_40905901 0.23 ENSDART00000064848
pglyrp5
peptidoglycan recognition protein 5
chr5_+_25585869 0.23 ENSDART00000138060
si:dkey-229d2.7
si:dkey-229d2.7
chr22_+_5478353 0.22 ENSDART00000160596
tppp
tubulin polymerization promoting protein
chr1_-_59411901 0.22 ENSDART00000167015
si:ch211-188p14.4
si:ch211-188p14.4
chr22_-_11438627 0.22 ENSDART00000007649
mid1ip1b
MID1 interacting protein 1b
chr25_-_19585010 0.22 ENSDART00000021340
sycp3
synaptonemal complex protein 3
chr9_-_33121535 0.22 ENSDART00000166371
ENSDART00000138052
zgc:172014
zgc:172014
chr16_+_23984179 0.22 ENSDART00000175879
apoc2
apolipoprotein C-II
chr17_-_20236228 0.21 ENSDART00000136490
ENSDART00000029380
bnip4
BCL2 interacting protein 4
chr15_+_618081 0.21 ENSDART00000181518
si:ch211-210b2.1
si:ch211-210b2.1
chr22_-_15593824 0.21 ENSDART00000123125
tpm4a
tropomyosin 4a
chr12_+_27537357 0.21 ENSDART00000136212
etv4
ets variant 4
chr4_-_43056627 0.21 ENSDART00000150269
si:dkey-54j5.2
si:dkey-54j5.2
chr3_-_32071468 0.21 ENSDART00000121979
BX511080.1

chr17_+_27456804 0.21 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
ctsl.1
cathepsin L.1
chr3_-_32927516 0.21 ENSDART00000140117
aoc2
amine oxidase, copper containing 2
chr2_+_26288301 0.21 ENSDART00000017668
ptbp1a
polypyrimidine tract binding protein 1a
chr17_+_26965351 0.21 ENSDART00000114215
ENSDART00000147192
grhl3
grainyhead-like transcription factor 3
chr3_-_1204341 0.21 ENSDART00000089646
fam234b
family with sequence similarity 234, member B
chr20_-_27225876 0.21 ENSDART00000149204
ENSDART00000149732
si:dkey-85n7.7
si:dkey-85n7.7
chr6_-_10752937 0.20 ENSDART00000135093
ola1
Obg-like ATPase 1
chr15_+_15232855 0.20 ENSDART00000033904
ENSDART00000139263
med29
mediator complex subunit 29
chr10_-_5016997 0.20 ENSDART00000101414
hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr19_+_3653976 0.20 ENSDART00000125673
nedd9
neural precursor cell expressed, developmentally down-regulated 9
chr8_+_39634114 0.20 ENSDART00000144293
msi1
musashi RNA-binding protein 1
chr6_+_50451337 0.20 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr4_+_68088529 0.20 ENSDART00000159155
znf1096
zinc finger protein 1096
chr13_-_32906265 0.20 ENSDART00000113823
ENSDART00000171114
ENSDART00000180035
ENSDART00000137570
si:dkey-18j18.3
si:dkey-18j18.3
chr16_-_46619967 0.20 ENSDART00000158341
tmem176l.3a
transmembrane protein 176l.3a
chr25_+_34014523 0.20 ENSDART00000182856
anxa2a
annexin A2a
chr17_-_23412705 0.20 ENSDART00000126995
si:ch211-149k12.3
si:ch211-149k12.3
chr5_-_20195350 0.20 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr14_-_28568107 0.20 ENSDART00000042850
ENSDART00000145502
insb
preproinsulin b
chr4_+_45504471 0.19 ENSDART00000150399
si:dkey-256i11.2
si:dkey-256i11.2
chr16_-_29557338 0.19 ENSDART00000058888
hormad1
HORMA domain containing 1
chr8_+_1187928 0.19 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr20_+_25568694 0.19 ENSDART00000063107
ENSDART00000063128
cyp2p7
cytochrome P450, family 2, subfamily P, polypeptide 7
chr17_+_30369396 0.19 ENSDART00000076611
greb1
growth regulation by estrogen in breast cancer 1
chr11_+_6374448 0.19 ENSDART00000135906
AL840638.2

chr6_-_27891961 0.19 ENSDART00000155116
im:7152348
im:7152348
chr24_-_26328721 0.19 ENSDART00000125468
apodb
apolipoprotein Db
chr20_+_42668875 0.19 ENSDART00000048890
slc22a2
solute carrier family 22 (organic cation transporter), member 2
chr25_+_35051656 0.19 ENSDART00000133379
hist2h3c
histone cluster 2, H3c
chr13_+_33688474 0.19 ENSDART00000161465
CABZ01087953.1

chr6_+_16468776 0.19 ENSDART00000109151
ENSDART00000114667
zgc:161969
zgc:161969
chr2_-_20923864 0.18 ENSDART00000006870
ptgs2a
prostaglandin-endoperoxide synthase 2a
chr6_-_41085692 0.18 ENSDART00000181463
srsf3a
serine/arginine-rich splicing factor 3a
chr7_-_27037990 0.18 ENSDART00000173561
nucb2a
nucleobindin 2a
chr24_-_17023392 0.18 ENSDART00000106058
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr24_-_8732519 0.18 ENSDART00000082351
tfap2a
transcription factor AP-2 alpha
chr15_-_47865063 0.18 ENSDART00000151600
h3f3b.1
H3 histone, family 3B.1
chr7_-_12968689 0.18 ENSDART00000173115
ENSDART00000013690
rplp2l
ribosomal protein, large P2, like
chr19_+_15440841 0.18 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr24_+_4373355 0.18 ENSDART00000179062
ENSDART00000093256
ENSDART00000138943
ccny
cyclin Y
chr10_+_38417512 0.18 ENSDART00000112457
samsn1b
SAM domain, SH3 domain and nuclear localisation signals 1b
chr4_-_35900331 0.18 ENSDART00000164413
zgc:174653
zgc:174653
chr3_-_16250527 0.18 ENSDART00000146699
ENSDART00000141181
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr23_-_4925641 0.18 ENSDART00000140861
ENSDART00000060718
taz
tafazzin
chr10_+_33982010 0.18 ENSDART00000180431
fryb
furry homolog b (Drosophila)
chr4_+_64577406 0.18 ENSDART00000159754
si:ch211-223a21.4
si:ch211-223a21.4
chr4_-_73739119 0.18 ENSDART00000108669
zgc:171551
zgc:171551
chr25_-_19584735 0.18 ENSDART00000137930
sycp3
synaptonemal complex protein 3
chr14_-_31087830 0.18 ENSDART00000002250
hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr3_+_24458204 0.18 ENSDART00000155028
ENSDART00000153551
cbx6b
chromobox homolog 6b
chr3_-_38918697 0.18 ENSDART00000145630
si:dkey-106c17.2
si:dkey-106c17.2
chr17_+_32374876 0.17 ENSDART00000183851
ywhaqb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr6_-_24301324 0.17 ENSDART00000171401
BX927081.1

chr23_+_27352072 0.17 ENSDART00000144762
si:dkey-9p24.5
si:dkey-9p24.5
chr23_+_43489182 0.17 ENSDART00000162062
znf341
zinc finger protein 341
chr22_-_21314821 0.17 ENSDART00000105546
ENSDART00000135388
cks2
CDC28 protein kinase regulatory subunit 2
chr4_+_37952218 0.17 ENSDART00000186865
si:dkeyp-82b4.2
si:dkeyp-82b4.2
chr4_+_58576146 0.17 ENSDART00000164911
si:ch211-212k5.4
si:ch211-212k5.4
chr8_-_13013123 0.17 ENSDART00000147802
dennd2da
DENN/MADD domain containing 2Da
chr4_+_42556555 0.17 ENSDART00000168536
znf1053
zinc finger protein 1053
chr13_+_24402406 0.17 ENSDART00000043002
rab1ab
RAB1A, member RAS oncogene family b
chr11_-_10770053 0.17 ENSDART00000179213
slc4a10a
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr3_-_15734358 0.17 ENSDART00000137325
mvp
major vault protein
chr22_+_10606573 0.17 ENSDART00000192638
rad54l2
RAD54 like 2
chr3_-_5394800 0.17 ENSDART00000181938
si:ch73-106l15.2
si:ch73-106l15.2
chr4_+_39766931 0.17 ENSDART00000138663
si:dkeyp-85d8.1
si:dkeyp-85d8.1
chr1_+_50538839 0.17 ENSDART00000020412
pkd2
polycystic kidney disease 2
chr16_-_51299061 0.16 ENSDART00000148677
serpinb1l4
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr9_+_32301456 0.16 ENSDART00000078608
ENSDART00000185153
ENSDART00000144947
hspe1
heat shock 10 protein 1
chr9_+_38158570 0.16 ENSDART00000059549
ENSDART00000133060
nifk
nucleolar protein interacting with the FHA domain of MKI67
chr18_-_1228688 0.16 ENSDART00000064403
nptnb
neuroplastin b
chr24_+_119680 0.16 ENSDART00000061973
tgfbr1b
transforming growth factor, beta receptor 1 b
chr17_-_17764801 0.16 ENSDART00000155261
slirp
SRA stem-loop interacting RNA binding protein
chr6_+_50452699 0.16 ENSDART00000115049
mych
myelocytomatosis oncogene homolog
chr4_+_63818718 0.16 ENSDART00000161177
si:dkey-30f3.2
si:dkey-30f3.2
chr16_+_23397785 0.16 ENSDART00000148961
s100a10b
S100 calcium binding protein A10b
chr24_+_16983269 0.16 ENSDART00000139176
ENSDART00000023833
eif2s3
eukaryotic translation initiation factor 2, subunit 3 gamma
chr5_-_36949476 0.16 ENSDART00000047269
h3f3c
H3 histone, family 3C
chr5_-_36948586 0.16 ENSDART00000193606
h3f3c
H3 histone, family 3C
chr4_+_14971239 0.16 ENSDART00000005985
smo
smoothened, frizzled class receptor
chr10_+_33895315 0.16 ENSDART00000142881
fryb
furry homolog b (Drosophila)
chr17_+_51744450 0.16 ENSDART00000190955
ENSDART00000149807
odc1
ornithine decarboxylase 1
chr23_-_44546124 0.16 ENSDART00000126779
ENSDART00000024082
psmb6
proteasome subunit beta 6
chr4_-_22671469 0.16 ENSDART00000050753
cd36
CD36 molecule (thrombospondin receptor)
chr25_+_30074947 0.16 ENSDART00000154849
si:ch211-147k10.5
si:ch211-147k10.5
chr20_+_34326874 0.16 ENSDART00000061659
ivns1abpa
influenza virus NS1A binding protein a
chr5_+_15202495 0.16 ENSDART00000144915
tbx1
T-box 1
chr20_-_3319642 0.16 ENSDART00000186743
ENSDART00000123096
marcksa
myristoylated alanine-rich protein kinase C substrate a
chr7_-_60831082 0.16 ENSDART00000073654
ENSDART00000136999
pcxb
pyruvate carboxylase b
chr19_+_16016038 0.16 ENSDART00000131319
ctps1a
CTP synthase 1a
chr25_-_18330503 0.16 ENSDART00000104496
dusp6
dual specificity phosphatase 6
chr25_-_16600811 0.15 ENSDART00000011397
cpa2
carboxypeptidase A2 (pancreatic)
chr15_+_4969128 0.15 ENSDART00000062856
rnf169
ring finger protein 169
chr21_+_22845317 0.15 ENSDART00000065555
birc2
baculoviral IAP repeat containing 2
chr5_-_2112030 0.15 ENSDART00000091932
gusb
glucuronidase, beta
chr13_-_45942000 0.15 ENSDART00000158534
ENSDART00000171822
ENSDART00000166442
si:ch211-62a1.4
si:ch211-62a1.4
chr9_+_5243476 0.15 ENSDART00000182735
CABZ01075242.1

chr20_-_54245256 0.15 ENSDART00000170482
prpf39
PRP39 pre-mRNA processing factor 39 homolog (yeast)
chr25_+_34845469 0.15 ENSDART00000145416
tmem231
transmembrane protein 231
chr4_-_45301719 0.15 ENSDART00000150282
si:ch211-162i8.2
si:ch211-162i8.2
chr14_-_7786260 0.15 ENSDART00000128218
tmem173
transmembrane protein 173
chr2_+_24762567 0.15 ENSDART00000078866
ifi30
interferon, gamma-inducible protein 30
chr10_-_42923385 0.15 ENSDART00000076731
ACOT12
acyl-CoA thioesterase 12
chr4_+_33461796 0.15 ENSDART00000150445
si:dkey-247i3.1
si:dkey-247i3.1
chr24_+_39638555 0.15 ENSDART00000078313
luc7l
LUC7-like (S. cerevisiae)
chr16_+_23398369 0.15 ENSDART00000037694
s100a10b
S100 calcium binding protein A10b
chr3_-_50139860 0.15 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr17_+_1323699 0.15 ENSDART00000172540
adssl1
adenylosuccinate synthase like 1
chr15_-_5780593 0.15 ENSDART00000163555
ENSDART00000082388
chchd2
coiled-coil-helix-coiled-coil-helix domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of nfil3-4+si:dkey-172o19.2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.1 0.5 GO:0071169 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 0.4 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.6 GO:0033034 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.3 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.1 0.3 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 0.3 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.1 0.4 GO:0046144 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.6 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.1 0.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.2 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.1 0.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.5 GO:0021885 forebrain cell migration(GO:0021885)
0.1 0.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.3 GO:0003418 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 0.2 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.1 0.2 GO:0015695 organic cation transport(GO:0015695)
0.1 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.2 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.2 GO:0003156 regulation of organ formation(GO:0003156)
0.1 0.2 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.0 0.2 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.2 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0090220 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.7 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:1901296 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 0.1 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.0 0.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.3 GO:0042664 negative regulation of endodermal cell fate specification(GO:0042664)
0.0 0.1 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0015865 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.2 GO:0060420 regulation of heart growth(GO:0060420)
0.0 0.0 GO:2000108 positive regulation of leukocyte apoptotic process(GO:2000108)
0.0 0.3 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.0 0.2 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.4 GO:0039014 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.1 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.1 GO:0019344 homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.0 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0060307 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.1 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.2 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.0 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.4 GO:0007568 aging(GO:0007568)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.0 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.0 0.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0046824 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 0.1 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.4 GO:0007286 spermatid development(GO:0007286) spermatid differentiation(GO:0048515)
0.0 0.0 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.0 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.1 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.1 GO:0036372 opsin transport(GO:0036372)
0.0 0.2 GO:0060324 face development(GO:0060324)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0030431 sleep(GO:0030431)
0.0 0.1 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.0 GO:0003250 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.2 GO:0031101 fin regeneration(GO:0031101)
0.0 0.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.0 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.0 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.0 GO:1901881 positive regulation of protein depolymerization(GO:1901881)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.2 GO:0097268 cytoophidium(GO:0097268)
0.1 0.2 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0005880 nuclear microtubule(GO:0005880)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.0 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.0 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.0 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.0 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.3 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.3 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.2 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.3 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.4 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.0 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.0 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.0 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport