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PRJNA195909:zebrafish embryo and larva development

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Results for nkx2.2a

Z-value: 1.11

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Transcription factors associated with nkx2.2a

Gene Symbol Gene ID Gene Info
nkx2.2a
ENSDARG00000053298 NK2 homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.2adr11_v1_chr17_-_42218652_42218652-0.891.4e-03Click!

Activity profile of nkx2.2a motif

Sorted Z-values of nkx2.2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_13690712 2.50 ENSDART00000065817
pou5f3
POU domain, class 5, transcription factor 3
chr24_-_33308045 2.30 ENSDART00000149711
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr2_-_38992304 2.02 ENSDART00000114085
ENSDART00000146812
si:ch211-119o8.6
si:ch211-119o8.6
chr11_+_42422371 1.85 ENSDART00000163780
dennd6aa
DENN/MADD domain containing 6Aa
chr11_+_42422638 1.75 ENSDART00000042599
ENSDART00000181175
dennd6aa
DENN/MADD domain containing 6Aa
chr23_-_27045231 1.75 ENSDART00000187979
zgc:66440
zgc:66440
chr17_+_6538733 1.65 ENSDART00000193712
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr13_+_47710434 1.63 ENSDART00000188724
TMEM87B
transmembrane protein 87B
chr8_+_52442622 1.60 ENSDART00000012758
zgc:77112
zgc:77112
chr16_-_54919260 1.51 ENSDART00000156533
kdf1a
keratinocyte differentiation factor 1a
chr2_-_15318786 1.47 ENSDART00000135851
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr2_-_15324837 1.44 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr15_+_29025090 1.40 ENSDART00000131755
si:ch211-137a8.2
si:ch211-137a8.2
chr2_+_7557912 1.39 ENSDART00000160053
ripk2
receptor-interacting serine-threonine kinase 2
chr18_-_43866001 1.38 ENSDART00000150218
treh
trehalase (brush-border membrane glycoprotein)
chr8_-_1698155 1.32 ENSDART00000186159
CABZ01065417.1

chr22_+_25249193 1.31 ENSDART00000171851
si:ch211-226h8.11
si:ch211-226h8.11
chr1_-_55248496 1.24 ENSDART00000098615
nanos3
nanos homolog 3
chr20_-_34750045 1.23 ENSDART00000186130
znf395b
zinc finger protein 395b
chr12_-_6880694 1.21 ENSDART00000171846
pcdh15b
protocadherin-related 15b
chr14_-_24110707 1.21 ENSDART00000133522
ENSDART00000123152
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr22_+_25236657 1.21 ENSDART00000138012
zgc:172218
zgc:172218
chr11_+_18157260 1.12 ENSDART00000144659
zgc:173545
zgc:173545
chr1_+_30723380 1.12 ENSDART00000127943
ENSDART00000062628
ENSDART00000127670
bora
bora, aurora kinase A activator
chr23_-_28120058 1.11 ENSDART00000087815
b4galnt1a
beta-1,4-N-acetyl-galactosaminyl transferase 1a
chr25_+_35375848 1.08 ENSDART00000155721
ano3
anoctamin 3
chr19_-_27827744 1.08 ENSDART00000181620
papd7
PAP associated domain containing 7
chr18_+_26428829 1.06 ENSDART00000190779
ENSDART00000193226
ENSDART00000110746
blm
Bloom syndrome, RecQ helicase-like
chr11_+_37638873 1.06 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
sh2d5
SH2 domain containing 5
chr24_+_15655069 1.06 ENSDART00000042943
ENSDART00000181296
fbxo15
F-box protein 15
chr24_+_41989108 1.06 ENSDART00000169725
zbtb14
zinc finger and BTB domain containing 14
chr19_+_34230108 1.04 ENSDART00000141950
galnt12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
chr16_-_28593951 1.03 ENSDART00000183322
rpp38
ribonuclease P/MRP 38 subunit
chr9_+_2762270 1.01 ENSDART00000123342
ENSDART00000001795
ENSDART00000177563
sp3a
sp3a transcription factor
chr12_-_33789006 1.00 ENSDART00000034550
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr12_-_33789218 0.99 ENSDART00000193258
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr21_+_19547806 0.99 ENSDART00000159707
ENSDART00000184869
ENSDART00000181321
ENSDART00000058487
ENSDART00000058485
rai14
retinoic acid induced 14
chr10_+_585719 0.99 ENSDART00000180167
smad4a
SMAD family member 4a
chr13_-_30996072 0.98 ENSDART00000181661
wdfy4
WDFY family member 4
chr1_-_40341306 0.96 ENSDART00000190649
maml3
mastermind-like transcriptional coactivator 3
chr14_+_29200772 0.95 ENSDART00000166608
TENM2
si:dkey-34l15.2
chr2_+_50477779 0.94 ENSDART00000122716
CABZ01067973.1

chr17_+_24809221 0.94 ENSDART00000082251
ENSDART00000147871
ENSDART00000130871
spdya
speedy/RINGO cell cycle regulator family member A
chr23_+_38245610 0.93 ENSDART00000191386
znf217
zinc finger protein 217
chr17_+_24809743 0.93 ENSDART00000135986
spdya
speedy/RINGO cell cycle regulator family member A
chr5_-_16472719 0.92 ENSDART00000162071
piwil2
piwi-like RNA-mediated gene silencing 2
chr5_-_37117778 0.92 ENSDART00000149138
il13ra2
interleukin 13 receptor, alpha 2
chr10_-_32851847 0.90 ENSDART00000134255
trim37
tripartite motif containing 37
chr1_+_8534698 0.90 ENSDART00000021504
smcr8b
Smith-Magenis syndrome chromosome region, candidate 8b
chr5_+_16117871 0.89 ENSDART00000090657
znrf3
zinc and ring finger 3
chr15_-_44601331 0.89 ENSDART00000161514
zgc:165508
zgc:165508
chr3_-_48603471 0.89 ENSDART00000189027
ndel1b
nudE neurodevelopment protein 1-like 1b
chr9_+_28140089 0.89 ENSDART00000046880
plekhm3
pleckstrin homology domain containing, family M, member 3
chr20_-_35512932 0.88 ENSDART00000137690
adgrf3b
adhesion G protein-coupled receptor F3b
chr10_+_36441124 0.88 ENSDART00000185626
uspl1
ubiquitin specific peptidase like 1
chr6_-_8465656 0.87 ENSDART00000178887
si:dkey-217d24.6
si:dkey-217d24.6
chr24_+_10039165 0.87 ENSDART00000144186
pou6f2
POU class 6 homeobox 2
chr22_+_23430688 0.86 ENSDART00000160457
dennd1b
DENN/MADD domain containing 1B
chr24_-_2423791 0.85 ENSDART00000190402
rreb1a
ras responsive element binding protein 1a
chr12_-_25150239 0.85 ENSDART00000038415
ENSDART00000135368
rhoq
ras homolog family member Q
chr11_-_11961706 0.84 ENSDART00000115249
abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr2_-_7185460 0.84 ENSDART00000092078
rc3h1b
ring finger and CCCH-type domains 1b
chr2_+_243778 0.84 ENSDART00000182262
CABZ01085887.1

chr3_+_19685873 0.82 ENSDART00000006490
tlk2
tousled-like kinase 2
chr21_+_3960583 0.82 ENSDART00000149788
setx
senataxin
chr8_+_3431671 0.82 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr2_-_10632431 0.82 ENSDART00000122709
mtf2
metal response element binding transcription factor 2
chr13_-_15799391 0.81 ENSDART00000124688
bag5
BCL2 associated athanogene 5
chr16_-_25400257 0.80 ENSDART00000040756
zgc:136493
zgc:136493
chr18_-_17145111 0.80 ENSDART00000090446
zc3h18
zinc finger CCCH-type containing 18
chr11_-_25257595 0.79 ENSDART00000123567
snai1a
snail family zinc finger 1a
chr2_-_22530969 0.79 ENSDART00000159641
znf644a
zinc finger protein 644a
chr16_-_1709328 0.79 ENSDART00000168865
ascc3
activating signal cointegrator 1 complex subunit 3
chr13_-_33317323 0.77 ENSDART00000110295
ENSDART00000144848
ENSDART00000136701
tmem234
transmembrane protein 234
chr24_+_17069420 0.77 ENSDART00000014787
pip4k2aa
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr22_-_20924564 0.76 ENSDART00000100642
ENSDART00000032770
ell
elongation factor RNA polymerase II
chr7_+_39688208 0.76 ENSDART00000189682
tbc1d14
TBC1 domain family, member 14
chr16_-_28594181 0.75 ENSDART00000059053
rpp38
ribonuclease P/MRP 38 subunit
chr16_-_22585289 0.74 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr16_+_11779534 0.74 ENSDART00000133497
si:dkey-250k15.4
si:dkey-250k15.4
chr25_-_13408760 0.74 ENSDART00000154445
gins3
GINS complex subunit 3
chr13_+_33368140 0.74 ENSDART00000033848
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr20_-_34750363 0.74 ENSDART00000152845
znf395b
zinc finger protein 395b
chr6_+_10338554 0.73 ENSDART00000186936
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr1_-_9858508 0.73 ENSDART00000147904
mad1l1
mitotic arrest deficient 1 like 1
chr24_-_26518972 0.73 ENSDART00000097792
tnikb
TRAF2 and NCK interacting kinase b
chr22_-_3299100 0.73 ENSDART00000160305
si:zfos-943e10.1
si:zfos-943e10.1
chr22_-_3299355 0.72 ENSDART00000190993
si:zfos-943e10.1
si:zfos-943e10.1
chr4_-_26035770 0.72 ENSDART00000124514
usp44
ubiquitin specific peptidase 44
chr14_-_24110062 0.72 ENSDART00000177062
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr6_+_1724889 0.71 ENSDART00000157415
acvr2ab
activin A receptor type 2Ab
chr13_+_46941930 0.71 ENSDART00000056962
fbxo5
F-box protein 5
chr10_+_41945890 0.71 ENSDART00000063013
ENSDART00000128313
tmem120b
transmembrane protein 120B
chr13_+_33368503 0.70 ENSDART00000139650
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr16_+_11779761 0.70 ENSDART00000140297
si:dkey-250k15.4
si:dkey-250k15.4
chr8_-_12432604 0.70 ENSDART00000133350
ENSDART00000140699
ENSDART00000101174
traf1
TNF receptor-associated factor 1
chr14_-_24110251 0.70 ENSDART00000079226
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr22_-_34979139 0.70 ENSDART00000116455
ENSDART00000133537
arhgap19
Rho GTPase activating protein 19
chr2_-_37280617 0.69 ENSDART00000190458
nadkb
NAD kinase b
chr20_-_28349144 0.69 ENSDART00000179690
ENSDART00000188059
ino80
INO80 complex subunit
chr7_+_22792895 0.69 ENSDART00000184407
rbm4.3
RNA binding motif protein 4.3
chr15_-_30714130 0.69 ENSDART00000156914
ENSDART00000154714
msi2b
musashi RNA-binding protein 2b
chr5_-_10082244 0.69 ENSDART00000036421
chek2
checkpoint kinase 2
chr5_+_13870340 0.68 ENSDART00000160690
hk2
hexokinase 2
chr1_+_30723677 0.68 ENSDART00000177900
bora
bora, aurora kinase A activator
chr21_-_13225402 0.68 ENSDART00000080347
wdr34
WD repeat domain 34
chr1_-_354115 0.68 ENSDART00000141590
ENSDART00000098627
pros1
protein S
chr13_+_15701596 0.67 ENSDART00000130832
trmt61a
tRNA methyltransferase 61A
chr7_+_53152108 0.67 ENSDART00000171350
cdh29
cadherin 29
chr15_+_1766734 0.66 ENSDART00000168250
cul3b
cullin 3b
chr15_+_15266025 0.66 ENSDART00000112974
ENSDART00000184450
c2cd3
C2 calcium-dependent domain containing 3
chr4_-_4570475 0.66 ENSDART00000184955
rassf3
Ras association (RalGDS/AF-6) domain family member 3
chr16_-_42175617 0.66 ENSDART00000084715
alkbh8
alkB homolog 8, tRNA methyltransferase
chr22_+_2229964 0.66 ENSDART00000112582
znf1161
zinc finger protein 1161
chr3_+_46315016 0.66 ENSDART00000157199
mkl2b
MKL/myocardin-like 2b
chr5_+_20035284 0.65 ENSDART00000191808
sgsm1a
small G protein signaling modulator 1a
chr2_+_51818039 0.65 ENSDART00000170353
acvr2bb
activin A receptor type 2Bb
chr22_+_6740039 0.65 ENSDART00000144122
CT583625.2

chr9_+_19039608 0.65 ENSDART00000055866
chmp2ba
charged multivesicular body protein 2Ba
chr2_+_37424261 0.64 ENSDART00000132427
phc3
polyhomeotic homolog 3 (Drosophila)
chr4_-_77252368 0.64 ENSDART00000111941
zgc:174310
zgc:174310
chr16_-_31284922 0.63 ENSDART00000142638
mroh1
maestro heat-like repeat family member 1
chr11_-_27953135 0.63 ENSDART00000168338
ece1
endothelin converting enzyme 1
chr19_+_14352332 0.62 ENSDART00000164386
arid1ab
AT rich interactive domain 1Ab (SWI-like)
chr16_-_4610255 0.62 ENSDART00000081852
ENSDART00000123253
ENSDART00000127554
ENSDART00000029485
arnt
aryl hydrocarbon receptor nuclear translocator
chr13_+_8840772 0.62 ENSDART00000059321
epcam
epithelial cell adhesion molecule
chr15_-_28569786 0.62 ENSDART00000127845
ssh2a
slingshot protein phosphatase 2a
chr16_-_39267185 0.61 ENSDART00000058550
ENSDART00000133642
gpd1l
glycerol-3-phosphate dehydrogenase 1 like
chr16_-_40459104 0.61 ENSDART00000032389
plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr10_-_10018120 0.60 ENSDART00000132375
strbp
spermatid perinuclear RNA binding protein
chr7_+_41887429 0.60 ENSDART00000115090
gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr3_-_31619463 0.60 ENSDART00000124559
moto
minamoto
chr7_-_64770456 0.60 ENSDART00000192618
zdhhc21
zinc finger, DHHC-type containing 21
chr10_+_44373349 0.59 ENSDART00000172191
snrnp35
small nuclear ribonucleoprotein 35 (U11/U12)
chr18_+_20468157 0.59 ENSDART00000100665
ENSDART00000147867
ENSDART00000060302
ENSDART00000180370
ddb2
damage-specific DNA binding protein 2
chr16_+_3185541 0.59 ENSDART00000024088
wdr21
WD repeat domain 21
chr3_-_11878490 0.59 ENSDART00000129961
coro7
coronin 7
chr19_+_24896409 0.59 ENSDART00000049840
eya3
EYA transcriptional coactivator and phosphatase 3
chr8_-_49304602 0.58 ENSDART00000147020
prickle3
prickle homolog 3
chr22_-_24757785 0.58 ENSDART00000078225
vtg5
vitellogenin 5
chr18_+_20225961 0.58 ENSDART00000045679
tle3a
transducin-like enhancer of split 3a
chr21_+_76739 0.57 ENSDART00000174654
ARSB
arylsulfatase B
chr16_+_17763848 0.56 ENSDART00000149408
ENSDART00000148878
them4
thioesterase superfamily member 4
chr5_-_54481692 0.56 ENSDART00000165719
fbxw5
F-box and WD repeat domain containing 5
chr11_+_34522554 0.56 ENSDART00000109833
zmat3
zinc finger, matrin-type 3
chr1_-_51261420 0.56 ENSDART00000168685
kif16ba
kinesin family member 16Ba
chr19_+_4051695 0.55 ENSDART00000166368
btr24
bloodthirsty-related gene family, member 24
chr15_-_17169935 0.55 ENSDART00000110111
cul5a
cullin 5a
chr9_-_46072805 0.55 ENSDART00000169682
hdac4
histone deacetylase 4
chr2_+_31437547 0.55 ENSDART00000141170
stam
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr7_+_71586485 0.55 ENSDART00000165582
smchd1
structural maintenance of chromosomes flexible hinge domain containing 1
chr12_+_33361948 0.54 ENSDART00000124982
fasn
fatty acid synthase
chr10_-_41156348 0.54 ENSDART00000058622
aak1b
AP2 associated kinase 1b
chr20_-_9194257 0.54 ENSDART00000133012
ylpm1
YLP motif containing 1
chr23_-_24952264 0.54 ENSDART00000192085
zbtb48
zinc finger and BTB domain containing 48
chr9_-_17783574 0.54 ENSDART00000146706
vwa8
von Willebrand factor A domain containing 8
chr24_-_31332087 0.53 ENSDART00000161179
abcd3a
ATP-binding cassette, sub-family D (ALD), member 3a
chr12_+_33320884 0.52 ENSDART00000188988
csnk1db
casein kinase 1, delta b
chr19_+_4066449 0.52 ENSDART00000162461
btr26
bloodthirsty-related gene family, member 26
chr12_+_34770531 0.52 ENSDART00000153320
slc38a10
solute carrier family 38, member 10
chr18_+_47301086 0.52 ENSDART00000009775
rbm7
RNA binding motif protein 7
chr3_-_31875138 0.52 ENSDART00000155298
limd2
LIM domain containing 2
chr24_+_37080771 0.52 ENSDART00000159942
kcnc3b
potassium voltage-gated channel, Shaw-related subfamily, member 3b
chr2_+_2967255 0.51 ENSDART00000167649
ENSDART00000166449
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr16_-_12097394 0.51 ENSDART00000103944
pex5
peroxisomal biogenesis factor 5
chr18_+_17600570 0.51 ENSDART00000175258
ENSDART00000151850
ENSDART00000151934
herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr6_-_31739709 0.51 ENSDART00000087964
cachd1
cache domain containing 1
chr16_-_12097558 0.51 ENSDART00000123142
pex5
peroxisomal biogenesis factor 5
chr21_-_37951819 0.51 ENSDART00000139549
si:dkey-38k9.5
si:dkey-38k9.5
chr11_-_34522249 0.50 ENSDART00000158616
pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr21_-_18086114 0.50 ENSDART00000143987
vav2
vav 2 guanine nucleotide exchange factor
chr2_+_38924975 0.50 ENSDART00000109219
rem2
RAS (RAD and GEM)-like GTP binding 2
chr20_-_53963515 0.49 ENSDART00000110252
ppp2r5cb
protein phosphatase 2, regulatory subunit B', gamma b
chr9_-_27748868 0.49 ENSDART00000190306
tbccd1
TBCC domain containing 1
chr13_-_42536642 0.48 ENSDART00000134533
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr20_+_812012 0.48 ENSDART00000179299
ENSDART00000137135
mei4
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr19_-_10656667 0.48 ENSDART00000081379
ENSDART00000151456
ENSDART00000143271
ENSDART00000182126
olah
oleoyl-ACP hydrolase
chr22_-_8006342 0.47 ENSDART00000162028
sc:d217
sc:d217
chr2_+_36121373 0.47 ENSDART00000187002
CT867973.2

chr5_-_55914268 0.47 ENSDART00000014049
wdr36
WD repeat domain 36
chr17_+_52612866 0.47 ENSDART00000182828
ENSDART00000191156
ENSDART00000188814
ENSDART00000109891
angel1
angel homolog 1 (Drosophila)
chr4_-_72287764 0.47 ENSDART00000125452
ENSDART00000189437
si:cabz01071911.3
si:cabz01071911.3
chr16_-_33105677 0.46 ENSDART00000145055
pnrc2
proline-rich nuclear receptor coactivator 2
chr21_-_27221535 0.46 ENSDART00000138266
mark2a
MAP/microtubule affinity-regulating kinase 2a
chr7_+_5956937 0.46 ENSDART00000170763
hist1h2a4
histone cluster 1 H2A family member 4
chr20_+_53368611 0.45 ENSDART00000060432
cdc40
cell division cycle 40 homolog (S. cerevisiae)
chr5_+_32009080 0.45 ENSDART00000186885
scai
suppressor of cancer cell invasion
chr3_+_16668609 0.45 ENSDART00000185646
zgc:55558
zgc:55558
chr17_-_35279422 0.45 ENSDART00000181587
adam17a
ADAM metallopeptidase domain 17a
chr1_-_28089557 0.44 ENSDART00000161024
ENSDART00000167875
snapc3
small nuclear RNA activating complex, polypeptide 3
chr25_-_10615504 0.44 ENSDART00000156797
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr1_+_41690402 0.44 ENSDART00000177298
fbxo41
F-box protein 41
chr16_-_8132742 0.43 ENSDART00000104323
snrka
SNF related kinase a
chr7_+_21331688 0.43 ENSDART00000128014
dnah2
dynein, axonemal, heavy chain 2
chr2_-_22286828 0.43 ENSDART00000168653
fam110b
family with sequence similarity 110, member B
chr2_-_10877228 0.43 ENSDART00000138718
ENSDART00000034246
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr19_-_4851411 0.43 ENSDART00000110398
fbxl20
F-box and leucine-rich repeat protein 20
chr2_+_33052360 0.43 ENSDART00000134651
rnf220a
ring finger protein 220a
chr20_+_51833030 0.43 ENSDART00000074330
taf1a
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A
chr3_-_26805455 0.43 ENSDART00000180648
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.5 1.4 GO:0005991 trehalose metabolic process(GO:0005991)
0.4 1.6 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.4 2.0 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.4 2.6 GO:0002931 response to ischemia(GO:0002931)
0.4 1.4 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3 1.5 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.3 2.5 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.3 1.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.2 0.7 GO:0042730 fibrinolysis(GO:0042730)
0.2 0.9 GO:0032801 receptor catabolic process(GO:0032801)
0.2 1.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2 1.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 1.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.5 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 0.9 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 0.9 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.2 0.5 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.2 0.5 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.2 0.6 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 1.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.7 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 1.9 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 1.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.8 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.4 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.5 GO:0051645 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.1 0.4 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.3 GO:0019557 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 1.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 0.7 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.3 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.1 1.0 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 1.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 2.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.6 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 0.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.6 GO:0007141 male meiosis I(GO:0007141)
0.1 1.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.3 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.2 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) intermediate mesoderm development(GO:0048389)
0.1 2.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.7 GO:0045444 fat cell differentiation(GO:0045444)
0.1 1.4 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 1.4 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.1 0.9 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.4 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.1 0.6 GO:0061056 sclerotome development(GO:0061056)
0.1 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.4 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.5 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.1 0.8 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 0.9 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:0090134 establishment or maintenance of cytoskeleton polarity(GO:0030952) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 1.1 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.8 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.7 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.2 GO:0045056 transcytosis(GO:0045056)
0.0 0.7 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.2 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.7 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0009146 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.0 0.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.5 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.7 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.2 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.0 0.5 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.4 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0030823 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.0 0.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 1.0 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.3 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.4 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.2 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.6 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509) late endosome to vacuole transport(GO:0045324)
0.0 0.7 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 0.2 GO:0015809 arginine transport(GO:0015809)
0.0 0.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.6 GO:0009411 response to UV(GO:0009411)
0.0 0.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0003188 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.0 0.1 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.8 GO:0003094 glomerular filtration(GO:0003094)
0.0 1.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:2000404 regulation of T cell migration(GO:2000404)
0.0 0.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666)
0.0 0.1 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.6 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0060465 pharynx development(GO:0060465)
0.0 0.6 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.9 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.6 GO:0032355 response to estradiol(GO:0032355)
0.0 1.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.8 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.6 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.5 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 1.0 GO:0050863 regulation of T cell activation(GO:0050863) regulation of leukocyte cell-cell adhesion(GO:1903037)
0.0 0.1 GO:0008584 male gonad development(GO:0008584)
0.0 0.5 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.1 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.4 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0060173 limb development(GO:0060173)
0.0 0.1 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520) regulation of neutrophil migration(GO:1902622)
0.0 0.3 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.2 GO:0086010 membrane depolarization(GO:0051899) membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.5 GO:0003333 amino acid transmembrane transport(GO:0003333)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0030681 fibrillar center(GO:0001650) multimeric ribonuclease P complex(GO:0030681)
0.2 0.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 0.9 GO:1990923 PET complex(GO:1990923)
0.2 0.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 1.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.2 2.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.7 GO:0000811 GINS complex(GO:0000811)
0.1 0.4 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.7 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 0.9 GO:0016234 inclusion body(GO:0016234)
0.1 0.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.6 GO:0035060 brahma complex(GO:0035060)
0.1 1.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.4 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.2 GO:0032420 stereocilium(GO:0032420)
0.1 1.5 GO:0043186 P granule(GO:0043186)
0.0 0.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.9 GO:0015030 Cajal body(GO:0015030)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 4.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0036452 ESCRT complex(GO:0036452)
0.0 2.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.0 GO:0000776 kinetochore(GO:0000776)
0.0 2.1 GO:0016607 nuclear speck(GO:0016607)
0.0 0.8 GO:0016604 nuclear body(GO:0016604)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0034451 acrosomal vesicle(GO:0001669) centriolar satellite(GO:0034451)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.6 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0004555 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.4 1.8 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.4 1.6 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 0.8 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3 0.8 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 1.9 GO:0001016 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.2 0.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 1.1 GO:0032183 SUMO binding(GO:0032183)
0.2 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 0.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 2.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.2 1.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 0.6 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.7 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 1.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 2.0 GO:0045159 myosin II binding(GO:0045159)
0.1 0.9 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.7 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.9 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 2.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 1.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.6 GO:0045735 nutrient reservoir activity(GO:0045735)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 0.3 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 1.1 GO:2001069 glycogen binding(GO:2001069)
0.1 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.3 GO:0016793 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.5 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 3.0 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.4 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.9 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 2.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 1.0 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.6 GO:0017069 snRNA binding(GO:0017069)
0.0 0.8 GO:0000049 tRNA binding(GO:0000049)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 1.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.7 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 2.6 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.4 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 3.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0019903 protein phosphatase binding(GO:0019903)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.7 PID ATM PATHWAY ATM pathway
0.1 1.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.2 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.9 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.8 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors