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PRJNA195909:zebrafish embryo and larva development

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Results for nkx2.2b

Z-value: 0.58

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Transcription factors associated with nkx2.2b

Gene Symbol Gene ID Gene Info
nkx2.2b
ENSDARG00000101549 NK2 homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.2bdr11_v1_chr20_+_48782068_487820680.274.9e-01Click!

Activity profile of nkx2.2b motif

Sorted Z-values of nkx2.2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22158784 0.85 ENSDART00000167850
crygm2d14
crystallin, gamma M2d14
chr9_-_22158325 0.83 ENSDART00000114568
crygm2d16
crystallin, gamma M2d16
chr8_+_26292560 0.79 ENSDART00000053463
mgll
monoglyceride lipase
chr9_-_18911608 0.78 ENSDART00000138785
si:dkey-239h2.3
si:dkey-239h2.3
chr14_-_25956804 0.74 ENSDART00000135627
ENSDART00000146022
ENSDART00000039660
sparc
secreted protein, acidic, cysteine-rich (osteonectin)
chr23_+_6795531 0.73 ENSDART00000092131
si:ch211-117c9.5
si:ch211-117c9.5
chr4_+_842010 0.73 ENSDART00000067461
si:ch211-152c2.3
si:ch211-152c2.3
chr6_-_19341184 0.70 ENSDART00000168236
ENSDART00000167674
mif4gda
MIF4G domain containing a
chr19_-_24555935 0.67 ENSDART00000132660
ENSDART00000162801
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr5_-_17601759 0.67 ENSDART00000138387
si:ch211-130h14.6
si:ch211-130h14.6
chr15_-_20468302 0.67 ENSDART00000018514
dlc
deltaC
chr22_+_11775269 0.66 ENSDART00000140272
krt96
keratin 96
chr19_-_24555623 0.63 ENSDART00000176022
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr7_-_27038488 0.63 ENSDART00000052731
ENSDART00000191382
nucb2a
nucleobindin 2a
chr16_+_23913943 0.63 ENSDART00000175404
ENSDART00000129525
apoa4b.1
apolipoprotein A-IV b, tandem duplicate 1
chr12_-_16595406 0.60 ENSDART00000166798
si:dkey-239j18.2
si:dkey-239j18.2
chr1_+_44442140 0.59 ENSDART00000190592
crybb1l2
crystallin, beta B1, like 2
chr2_-_53525896 0.58 ENSDART00000057053
im:7138239
im:7138239
chr22_+_20720808 0.57 ENSDART00000171321
si:dkey-211f22.5
si:dkey-211f22.5
chr12_-_16595177 0.54 ENSDART00000133962
si:dkey-239j18.2
si:dkey-239j18.2
chr14_-_498979 0.54 ENSDART00000171976
spry1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr11_-_30636163 0.54 ENSDART00000140516
zgc:153665
zgc:153665
chr11_+_8660158 0.53 ENSDART00000169141
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a
chr23_-_24394719 0.53 ENSDART00000044918
epha2b
eph receptor A2 b
chr12_-_48671612 0.52 ENSDART00000007202
zgc:92749
zgc:92749
chr7_+_20109968 0.52 ENSDART00000146335
zgc:114045
zgc:114045
chr19_+_40861853 0.52 ENSDART00000126470
zgc:85777
zgc:85777
chr8_-_25074319 0.50 ENSDART00000134190
sort1b
sortilin 1b
chr25_-_29134000 0.49 ENSDART00000172027
ENSDART00000190447
parp6b
poly (ADP-ribose) polymerase family, member 6b
chr6_-_41085443 0.49 ENSDART00000143944
ENSDART00000028217
srsf3a
serine/arginine-rich splicing factor 3a
chr3_-_15999501 0.49 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr7_-_38087865 0.48 ENSDART00000052366
cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr3_-_16000168 0.48 ENSDART00000160628
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr6_-_13408680 0.46 ENSDART00000151566
fmnl2b
formin-like 2b
chr21_-_37733571 0.44 ENSDART00000176214
mpp1
membrane protein, palmitoylated 1
chr14_-_42997145 0.43 ENSDART00000172801
pcdh10b
protocadherin 10b
chr6_-_41085692 0.43 ENSDART00000181463
srsf3a
serine/arginine-rich splicing factor 3a
chr13_+_44857087 0.43 ENSDART00000017770
zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr14_+_21861099 0.43 ENSDART00000032141
spon2a
spondin 2a, extracellular matrix protein
chr20_+_33904258 0.43 ENSDART00000170930
rxrgb
retinoid X receptor, gamma b
chr12_-_26407092 0.42 ENSDART00000178687
myoz1b
myozenin 1b
chr3_+_24134418 0.42 ENSDART00000156204
si:ch211-246i5.5
si:ch211-246i5.5
chr21_+_26389391 0.41 ENSDART00000077197
tmsb
thymosin, beta
chr19_+_38422059 0.41 ENSDART00000035093
col9a2
procollagen, type IX, alpha 2
chr12_+_6002715 0.41 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr1_+_15137901 0.40 ENSDART00000111475
pcdh7a
protocadherin 7a
chr2_-_32352946 0.40 ENSDART00000144870
ENSDART00000077151
asap1a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr23_+_6795709 0.39 ENSDART00000149136
si:ch211-117c9.5
si:ch211-117c9.5
chr15_+_13984879 0.38 ENSDART00000159438
zgc:162730
zgc:162730
chr4_+_2092683 0.38 ENSDART00000067423
frs2a
fibroblast growth factor receptor substrate 2a
chr23_-_4925641 0.38 ENSDART00000140861
ENSDART00000060718
taz
tafazzin
chr4_+_26449406 0.38 ENSDART00000183291
CU137645.3

chr23_+_19813677 0.38 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr2_+_26498446 0.37 ENSDART00000078412
rps8a
ribosomal protein S8a
chr10_-_7885654 0.37 ENSDART00000185768
BX294661.2

chr7_-_16562200 0.37 ENSDART00000169093
ENSDART00000173491
csrp3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr16_+_4658250 0.36 ENSDART00000006212
LIN28A
si:ch1073-284b18.2
chr7_-_56793739 0.36 ENSDART00000082842
si:ch211-146m13.3
si:ch211-146m13.3
chr6_-_7439490 0.36 ENSDART00000188825
fkbp11
FK506 binding protein 11
chr5_-_47727819 0.36 ENSDART00000165249
cox7c
cytochrome c oxidase, subunit VIIc
chr12_-_8511185 0.36 ENSDART00000179910
CR932364.1

chr19_+_47135677 0.36 ENSDART00000139692
si:ch211-229b6.1
si:ch211-229b6.1
chr16_+_8716800 0.36 ENSDART00000124693
ENSDART00000181961
cabz01093075.1
cabz01093075.1
chr12_+_9880493 0.36 ENSDART00000055019
ndufa4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4
chr1_+_36651059 0.36 ENSDART00000187475
ednraa
endothelin receptor type Aa
chr21_-_40835069 0.35 ENSDART00000004686
limk1b
LIM domain kinase 1b
chr1_+_52560549 0.35 ENSDART00000167514
abca1a
ATP-binding cassette, sub-family A (ABC1), member 1A
chr23_+_25354856 0.35 ENSDART00000109023
ENSDART00000147440
fmnl3
formin-like 3
chr20_+_492529 0.35 ENSDART00000141709
FO904980.1

chr5_-_58939460 0.35 ENSDART00000122413
mcama
melanoma cell adhesion molecule a
chr7_-_69636502 0.34 ENSDART00000126739
tspan5a
tetraspanin 5a
chr9_-_23156908 0.33 ENSDART00000135461
lypd6b
LY6/PLAUR domain containing 6B
chr5_-_60159116 0.33 ENSDART00000147675
si:dkey-280e8.1
si:dkey-280e8.1
chr25_-_16755340 0.33 ENSDART00000124729
ENSDART00000110859
ribc2
RIB43A domain with coiled-coils 2
chr3_-_27647845 0.33 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr16_-_51288178 0.33 ENSDART00000079864
zgc:173729
zgc:173729
chr18_+_37272568 0.32 ENSDART00000132749
tmem123
transmembrane protein 123
chr18_-_40481028 0.32 ENSDART00000134177
zgc:101040
zgc:101040
chr14_-_10617923 0.32 ENSDART00000133723
ENSDART00000131939
ENSDART00000136649
si:dkey-92i17.2
si:dkey-92i17.2
chr1_+_45351890 0.32 ENSDART00000145486
si:ch211-243a20.3
si:ch211-243a20.3
chr3_-_26122353 0.31 ENSDART00000111042
ENSDART00000161427
hsp70.2
heat shock cognate 70-kd protein, tandem duplicate 2
chr4_+_6032640 0.31 ENSDART00000157487
tfec
transcription factor EC
chr4_+_33225161 0.31 ENSDART00000150851
si:dkey-247i3.5
si:dkey-247i3.5
chr13_-_43238578 0.30 ENSDART00000161017
eif3s6ip
eukaryotic translation initiation factor 3, subunit 6 interacting protein
chr6_+_49255706 0.30 ENSDART00000156866
si:dkey-183k8.2
si:dkey-183k8.2
chr3_+_28581397 0.29 ENSDART00000150893
sept12
septin 12
chr16_+_32995882 0.29 ENSDART00000170157
prss35
protease, serine, 35
chr4_+_58576146 0.29 ENSDART00000164911
si:ch211-212k5.4
si:ch211-212k5.4
chr14_+_18781082 0.28 ENSDART00000108793
si:ch211-111e20.1
si:ch211-111e20.1
chr12_+_30233977 0.28 ENSDART00000188135
afap1l2
actin filament associated protein 1-like 2
chr19_-_22328154 0.28 ENSDART00000090464
si:ch73-196l6.5
si:ch73-196l6.5
chr16_-_11798994 0.27 ENSDART00000135408
cnfn
cornifelin
chr1_+_12767318 0.27 ENSDART00000162652
pcdh10a
protocadherin 10a
chr12_+_30234209 0.27 ENSDART00000102081
afap1l2
actin filament associated protein 1-like 2
chr16_+_16933002 0.27 ENSDART00000173163
myh14
myosin, heavy chain 14, non-muscle
chr15_-_1198886 0.27 ENSDART00000063285
lxn
latexin
chr21_-_42055872 0.27 ENSDART00000144767
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr23_-_17470146 0.27 ENSDART00000002398
trim101
tripartite motif containing 101
chr9_+_21722733 0.26 ENSDART00000102021
sox1a
SRY (sex determining region Y)-box 1a
chr21_+_9628854 0.26 ENSDART00000161753
ENSDART00000160711
mapk10
mitogen-activated protein kinase 10
chr10_+_44984946 0.26 ENSDART00000182520
h2afvb
H2A histone family, member Vb
chr21_+_33454147 0.26 ENSDART00000053208
rps14
ribosomal protein S14
chr4_+_28356606 0.25 ENSDART00000192995
si:ch73-263o4.4
si:ch73-263o4.4
chr4_+_62184754 0.25 ENSDART00000168844
si:dkeyp-35e5.9
si:dkeyp-35e5.9
chr19_-_35010226 0.25 ENSDART00000051750
ENSDART00000155525
si:rp71-45k5.4
si:rp71-45k5.4
chr25_+_10485103 0.24 ENSDART00000104576
psmd13
proteasome 26S subunit, non-ATPase 13
chr4_-_25836684 0.24 ENSDART00000142491
ndufa12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr7_+_34231782 0.24 ENSDART00000173547
lctla
lactase-like a
chr3_+_60716904 0.24 ENSDART00000168280
foxj1a
forkhead box J1a
chr23_+_36653376 0.24 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr16_+_23087326 0.24 ENSDART00000167518
ENSDART00000161087
efna3b
ephrin-A3b
chr4_-_22311610 0.24 ENSDART00000137814
hcls1
hematopoietic cell-specific Lyn substrate 1
chr9_+_25776971 0.24 ENSDART00000146011
zeb2a
zinc finger E-box binding homeobox 2a
chr7_+_29992889 0.24 ENSDART00000055936
isl2b
ISL LIM homeobox 2b
chr20_-_30920356 0.24 ENSDART00000022951
kif25
kinesin family member 25
chr14_-_10371638 0.24 ENSDART00000003879
fam199x
family with sequence similarity 199, X-linked
chr11_+_24900123 0.24 ENSDART00000044987
ENSDART00000148023
timm17a
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr19_+_40856807 0.23 ENSDART00000139083
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr12_-_35054354 0.23 ENSDART00000075351
zgc:112285
zgc:112285
chr4_-_9891874 0.23 ENSDART00000067193
adm2a
adrenomedullin 2a
chr4_+_58016732 0.23 ENSDART00000165777
CT027609.1

chr2_-_21618629 0.23 ENSDART00000027587
ralab
v-ral simian leukemia viral oncogene homolog Ab (ras related)
chr2_-_3038904 0.23 ENSDART00000186795
guk1a
guanylate kinase 1a
chr10_-_27197044 0.23 ENSDART00000137928
auts2a
autism susceptibility candidate 2a
chr16_+_20915319 0.22 ENSDART00000079383
hoxa9b
homeobox A9b
chr19_-_19339285 0.22 ENSDART00000158413
ENSDART00000170479
cspg5b
chondroitin sulfate proteoglycan 5b
chr8_-_14484599 0.22 ENSDART00000057644
lhx4
LIM homeobox 4
chr25_-_22363253 0.22 ENSDART00000073573
ENSDART00000162103
ccdc33
coiled-coil domain containing 33
chr5_-_28052883 0.22 ENSDART00000188791
zgc:113436
zgc:113436
chr20_-_4766645 0.22 ENSDART00000147071
ENSDART00000152398
ak7a
adenylate kinase 7a
chr11_+_18873113 0.22 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr21_+_30549512 0.22 ENSDART00000132831
rab38c
RAB38c, member of RAS oncogene family
chr10_-_44924289 0.22 ENSDART00000171267
tuba7l
tubulin, alpha 7 like
chr22_-_20720427 0.21 ENSDART00000105532
oaz1a
ornithine decarboxylase antizyme 1a
chr8_+_14058646 0.21 ENSDART00000080852
ugt5e1
UDP glucuronosyltransferase 5 family, polypeptide E1
chr4_-_5333971 0.21 ENSDART00000067375
osgep
O-sialoglycoprotein endopeptidase
chr19_-_48330287 0.21 ENSDART00000162244
si:ch73-359m17.7
si:ch73-359m17.7
chr12_+_30168342 0.21 ENSDART00000142756
ablim1b
actin binding LIM protein 1b
chr9_+_23900703 0.21 ENSDART00000127859
trim63b
tripartite motif containing 63b
chr2_-_37956768 0.21 ENSDART00000034595
cbln10
cerebellin 10
chr2_-_7696287 0.21 ENSDART00000190769
CABZ01055306.1

chr1_+_23784905 0.21 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit2
slit homolog 2 (Drosophila)
chr9_+_55056310 0.21 ENSDART00000047080
gpr143
G protein-coupled receptor 143
chr8_+_22582146 0.20 ENSDART00000157655
ENSDART00000189892
CT583651.2

chr10_-_20706109 0.20 ENSDART00000124751
kcnip3b
Kv channel interacting protein 3b, calsenilin
chr12_+_36109507 0.20 ENSDART00000175409
map2k6
mitogen-activated protein kinase kinase 6
chr4_-_25215968 0.20 ENSDART00000066932
ENSDART00000066933
itih2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_-_72609735 0.20 ENSDART00000174299
ENSDART00000159227
si:cabz01054394.6
si:cabz01054394.6
chr1_+_33328857 0.20 ENSDART00000137151
mxra5a
matrix-remodelling associated 5a
chr22_-_4892937 0.20 ENSDART00000147002
si:ch73-256j6.4
si:ch73-256j6.4
chr10_+_9372702 0.19 ENSDART00000021100
lhx6
LIM homeobox 6
chr8_+_25302172 0.19 ENSDART00000046182
ENSDART00000145316
gstm.3
glutathione S-transferase mu tandem duplicate 3
chr5_-_9073433 0.19 ENSDART00000099891
atp5meb
ATP synthase membrane subunit eb
chr7_-_35083184 0.19 ENSDART00000100253
ENSDART00000135250
ENSDART00000173511
agrp
agouti related neuropeptide
chr6_-_13187168 0.19 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
adam23a
ADAM metallopeptidase domain 23a
chr12_-_30548244 0.19 ENSDART00000193616
zgc:158404
zgc:158404
chr15_+_5299404 0.19 ENSDART00000155410
or122-2
odorant receptor, family E, subfamily 122, member 2
chr4_+_4267451 0.19 ENSDART00000192069
ano2
anoctamin 2
chr8_-_9118958 0.19 ENSDART00000037922
slc6a8
solute carrier family 6 (neurotransmitter transporter), member 8
chr2_+_1487118 0.18 ENSDART00000147283
c8a
complement component 8, alpha polypeptide
chr24_+_5935377 0.18 ENSDART00000191989
ENSDART00000185932
ENSDART00000131768
abi1a
abl-interactor 1a
chr6_-_13200585 0.18 ENSDART00000185321
eef1b2
eukaryotic translation elongation factor 1 beta 2
chr21_+_25793970 0.18 ENSDART00000101217
CLDN4 (1 of many)
zgc:136892
chr14_+_17376940 0.18 ENSDART00000054590
ENSDART00000010148
spon2b
spondin 2b, extracellular matrix protein
chr4_+_65614183 0.18 ENSDART00000180387
si:dkey-205i10.1
si:dkey-205i10.1
chr19_-_22478888 0.18 ENSDART00000090679
pleca
plectin a
chr4_-_17838179 0.17 ENSDART00000146931
avpr2l
arginine vasopressin receptor 2, like
chr4_+_31405646 0.17 ENSDART00000128732
si:rp71-5o12.3
si:rp71-5o12.3
chr7_+_57108823 0.17 ENSDART00000184943
ENSDART00000055956
enosf1
enolase superfamily member 1
chr21_+_44112914 0.17 ENSDART00000062836
fgf1b
fibroblast growth factor 1b
chr15_+_31526225 0.17 ENSDART00000154456
wdr95
WD40 repeat domain 95
chr3_-_7524363 0.17 ENSDART00000162970
znf1001
zinc finger protein 1001
chr11_+_30314885 0.17 ENSDART00000187418
ENSDART00000123244
ugt1b2
UDP glucuronosyltransferase 1 family, polypeptide B2
chr18_-_6766354 0.17 ENSDART00000132611
adm2b
adrenomedullin 2b
chr10_+_21722892 0.17 ENSDART00000162855
pcdh1g13
protocadherin 1 gamma 13
chr2_-_1514001 0.17 ENSDART00000057736
c8b
complement component 8, beta polypeptide
chr16_-_41465542 0.17 ENSDART00000169116
ENSDART00000187446
cpne4a
copine IVa
chr6_-_57938043 0.17 ENSDART00000171073
tox2
TOX high mobility group box family member 2
chr2_-_59376735 0.17 ENSDART00000193624
ftr38
finTRIM family, member 38
chr12_-_25612170 0.17 ENSDART00000077155
six2b
SIX homeobox 2b
chr15_+_24691088 0.16 ENSDART00000110618
LRRC75A
si:dkey-151p21.7
chr5_-_67499279 0.16 ENSDART00000128050
si:dkey-251i10.3
si:dkey-251i10.3
chr14_-_858985 0.16 ENSDART00000148687
ENSDART00000149375
slc34a1a
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr22_+_30839702 0.16 ENSDART00000139849
ENSDART00000135775
si:dkey-49n23.3
si:dkey-49n23.3
chr19_-_677713 0.16 ENSDART00000025146
slc6a19a.1
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 1
chr4_+_69823638 0.16 ENSDART00000165786
znf1087
zinc finger protein 1087
chr2_-_51757328 0.16 ENSDART00000189286
si:ch211-9d9.1
si:ch211-9d9.1
chr4_+_43679421 0.16 ENSDART00000132945
zgc:173705
zgc:173705
chr1_-_46832880 0.16 ENSDART00000142406
si:ch73-160h15.3
si:ch73-160h15.3
chr5_-_37900350 0.16 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
tmprss13b
transmembrane protease, serine 13b
chr24_-_36680261 0.16 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr2_-_32386942 0.16 ENSDART00000131408
ubtfl
upstream binding transcription factor, like
chr20_-_32188897 0.16 ENSDART00000133887
si:ch211-51a19.5
si:ch211-51a19.5
chr22_+_1317353 0.15 ENSDART00000187250
si:ch73-138e16.6
si:ch73-138e16.6
chr23_+_1078072 0.15 ENSDART00000159263
ENSDART00000053527
slc34a2b
solute carrier family 34 (type II sodium/phosphate cotransporter), member 2b
chr5_+_26795773 0.15 ENSDART00000145631
tcn2
transcobalamin II
chr23_-_19827411 0.15 ENSDART00000187964
haus7
HAUS augmin-like complex, subunit 7
chr18_-_14691727 0.15 ENSDART00000010129
pdf
peptide deformylase, mitochondrial
chr4_+_76441823 0.15 ENSDART00000163932
si:dkey-16p6.1
si:dkey-16p6.1
chr19_-_29832876 0.15 ENSDART00000005119
eif3i
eukaryotic translation initiation factor 3, subunit I

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.2 0.5 GO:0003156 regulation of organ formation(GO:0003156)
0.1 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.4 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.4 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.6 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.0 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.4 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.2 GO:0015074 DNA integration(GO:0015074)
0.1 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.2 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.0 0.1 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.2 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.4 GO:0032048 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.2 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.2 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 0.7 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.5 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.5 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0 0.2 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)
0.0 0.1 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.2 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0015893 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.1 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.0 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0060092 inhibitory postsynaptic potential(GO:0060080) regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 2.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0030323 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.0 0.3 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.0 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.0 0.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.1 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.1 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.0 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.0 GO:0030689 Noc complex(GO:0030689)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.3 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.7 GO:0008494 translation activator activity(GO:0008494)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.4 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.2 GO:0072545 tyrosine binding(GO:0072545)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.3 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.4 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 1.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 2.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.6 GO:0019956 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions