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PRJNA195909:zebrafish embryo and larva development

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Results for nkx2.3+nkx2.7

Z-value: 1.27

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Transcription factors associated with nkx2.3+nkx2.7

Gene Symbol Gene ID Gene Info
nkx2.7
ENSDARG00000021232 NK2 transcription factor related 7
nkx2.3
ENSDARG00000039095 NK2 homeobox 3
nkx2.3
ENSDARG00000113490 NK2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.3dr11_v1_chr13_-_40411908_404119170.808.9e-03Click!
nkx2.7dr11_v1_chr8_-_50287949_502879490.561.2e-01Click!

Activity profile of nkx2.3+nkx2.7 motif

Sorted Z-values of nkx2.3+nkx2.7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_44439661 2.23 ENSDART00000100309
crybb1l2
crystallin, beta B1, like 2
chr12_+_15008582 2.07 ENSDART00000003847
mylpfb
myosin light chain, phosphorylatable, fast skeletal muscle b
chr14_-_3381303 2.05 ENSDART00000171601
im:7150988
im:7150988
chr25_+_31277415 1.90 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr5_-_14373662 1.78 ENSDART00000183694
tet3
tet methylcytosine dioxygenase 3
chr3_+_60721342 1.66 ENSDART00000157772
foxj1a
forkhead box J1a
chr8_-_50147948 1.65 ENSDART00000149010
hp
haptoglobin
chr25_+_20089986 1.64 ENSDART00000143441
ENSDART00000184073
tnni4b.2
troponin I4b, tandem duplicate 2
chr5_+_32206378 1.62 ENSDART00000126873
ENSDART00000051361
myhz2
myosin, heavy polypeptide 2, fast muscle specific
chr19_-_5358443 1.61 ENSDART00000105036
cyt1l
type I cytokeratin, enveloping layer, like
chr15_-_15357178 1.53 ENSDART00000106120
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr13_+_1726953 1.49 ENSDART00000103004
zmp:0000000760
zmp:0000000760
chr1_-_59287410 1.47 ENSDART00000158011
ENSDART00000170580
col5a3b
collagen, type V, alpha 3b
chr21_+_7582036 1.45 ENSDART00000135485
ENSDART00000027268
otpa
orthopedia homeobox a
chr5_+_37854685 1.41 ENSDART00000051222
ENSDART00000185283
ins
preproinsulin
chr13_+_25449681 1.40 ENSDART00000101328
atoh7
atonal bHLH transcription factor 7
chr17_+_23298928 1.39 ENSDART00000153652
zgc:165461
zgc:165461
chr11_+_30244356 1.37 ENSDART00000036050
ENSDART00000150080
rs1a
retinoschisin 1a
chr7_-_38658411 1.35 ENSDART00000109463
ENSDART00000017155
npsn
nephrosin
chr5_-_28679135 1.33 ENSDART00000193585
tnc
tenascin C
chr21_-_43015383 1.32 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr21_+_28478663 1.30 ENSDART00000077887
ENSDART00000134150
slc22a6l
solute carrier family 22 (organic anion transporter), member 6, like
chr25_-_18953322 1.27 ENSDART00000155927
si:ch211-68a17.7
si:ch211-68a17.7
chr19_+_1184878 1.25 ENSDART00000163539
scrt1a
scratch family zinc finger 1a
chr4_+_12931763 1.25 ENSDART00000016382
wif1
wnt inhibitory factor 1
chr18_+_27318589 1.25 ENSDART00000037813
cd81b
CD81 molecule b
chr12_+_24342303 1.24 ENSDART00000111239
nrxn1a
neurexin 1a
chr7_-_27038488 1.23 ENSDART00000052731
ENSDART00000191382
nucb2a
nucleobindin 2a
chr24_+_38301080 1.23 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr3_+_23687909 1.22 ENSDART00000046638
hoxb8a
homeobox B8a
chr14_-_5678457 1.21 ENSDART00000012116
tlx2
T cell leukemia homeobox 2
chr12_-_25916530 1.20 ENSDART00000186386
sncgb
synuclein, gamma b (breast cancer-specific protein 1)
chr13_-_36391496 1.17 ENSDART00000100217
ENSDART00000140243
actn1
actinin, alpha 1
chr9_-_33107237 1.17 ENSDART00000013918
casq2
calsequestrin 2
chr17_-_31659670 1.16 ENSDART00000030448
vsx2
visual system homeobox 2
chr24_+_2519761 1.16 ENSDART00000106619
nrn1a
neuritin 1a
chr4_+_14900042 1.16 ENSDART00000018261
akr1b1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr6_+_3828560 1.16 ENSDART00000185273
ENSDART00000179091
gad1b
glutamate decarboxylase 1b
chr23_-_42232124 1.16 ENSDART00000149944
gpx7
glutathione peroxidase 7
chr16_-_55028740 1.14 ENSDART00000156368
ENSDART00000161704
zgc:114181
zgc:114181
chr7_-_28148310 1.14 ENSDART00000044208
lmo1
LIM domain only 1
chr19_-_42391383 1.14 ENSDART00000110075
ENSDART00000087002
plekho1a
pleckstrin homology domain containing, family O member 1a
chr10_-_17484762 1.09 ENSDART00000137905
ENSDART00000007961
nt5c2l1
5'-nucleotidase, cytosolic II, like 1
chr9_+_51265283 1.08 ENSDART00000137426
gcgb
glucagon b
chr17_-_21066075 1.07 ENSDART00000078763
ENSDART00000104327
vsx1
visual system homeobox 1 homolog, chx10-like
chr17_-_29119362 1.07 ENSDART00000104204
foxg1a
forkhead box G1a
chr5_-_42272517 1.06 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr13_+_28417297 1.05 ENSDART00000043658
slc2a15a
solute carrier family 2 (facilitated glucose transporter), member 15a
chr25_+_34014523 1.05 ENSDART00000182856
anxa2a
annexin A2a
chr1_-_36151377 1.03 ENSDART00000037516
znf827
zinc finger protein 827
chr19_-_28789404 1.03 ENSDART00000191453
ENSDART00000026992
sox4a
SRY (sex determining region Y)-box 4a
chr20_+_28861435 1.03 ENSDART00000142678
slc10a1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr15_+_36115955 1.03 ENSDART00000032702
sst1.2
somatostatin 1, tandem duplicate 2
chr1_+_52929185 1.01 ENSDART00000147683
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr17_-_44247707 1.01 ENSDART00000126097
otx2b
orthodenticle homeobox 2b
chr11_-_27501027 1.00 ENSDART00000065889
wnt7aa
wingless-type MMTV integration site family, member 7Aa
chr8_-_31075015 0.99 ENSDART00000010993
slc20a1a
solute carrier family 20, member 1a
chr6_-_8311044 0.98 ENSDART00000129674
slc44a2
solute carrier family 44 (choline transporter), member 2
chr14_+_25465346 0.97 ENSDART00000173436
si:dkey-280e21.3
si:dkey-280e21.3
chr7_-_24699985 0.97 ENSDART00000052802
calb2b
calbindin 2b
chr21_+_28958471 0.96 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr21_+_35215810 0.95 ENSDART00000135256
ubtd2
ubiquitin domain containing 2
chr1_-_38195012 0.94 ENSDART00000020409
hand2
heart and neural crest derivatives expressed 2
chr12_+_5081759 0.94 ENSDART00000164178
prrt2
proline-rich transmembrane protein 2
chr13_-_40401870 0.94 ENSDART00000128951
nkx3.3
NK3 homeobox 3
chr11_+_7324704 0.93 ENSDART00000031937
diras1a
DIRAS family, GTP-binding RAS-like 1a
chr4_-_4387012 0.91 ENSDART00000191836
CU468826.3
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr14_-_24410673 0.91 ENSDART00000125923
cxcl14
chemokine (C-X-C motif) ligand 14
chr24_-_6158933 0.90 ENSDART00000021609
gad2
glutamate decarboxylase 2
chr6_+_23887314 0.90 ENSDART00000163188
znf648
zinc finger protein 648
chr16_+_20910186 0.90 ENSDART00000046766
hoxa10b
homeobox A10b
chr3_+_26081343 0.90 ENSDART00000134647
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr15_-_1822548 0.88 ENSDART00000082026
ENSDART00000180230
mmp28
matrix metallopeptidase 28
chr23_-_24263474 0.87 ENSDART00000160312
hspb7
heat shock protein family, member 7 (cardiovascular)
chr19_+_43297546 0.87 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr18_+_40381102 0.83 ENSDART00000136588
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr4_+_12615836 0.83 ENSDART00000003583
lmo3
LIM domain only 3
chr14_-_9522364 0.82 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr5_-_58939460 0.81 ENSDART00000122413
mcama
melanoma cell adhesion molecule a
chr10_-_7756865 0.81 ENSDART00000114373
ENSDART00000125407
ENSDART00000016317
loxa
lysyl oxidase a
chr20_+_28861629 0.80 ENSDART00000187274
ENSDART00000047826
slc10a1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr10_+_9372702 0.79 ENSDART00000021100
lhx6
LIM homeobox 6
chr9_-_23118350 0.77 ENSDART00000020884
lypd6
LY6/PLAUR domain containing 6
chr1_+_40023640 0.77 ENSDART00000101623
lgi2b
leucine-rich repeat LGI family, member 2b
chr25_+_18965430 0.77 ENSDART00000169742
tdg.1
thymine DNA glycosylase, tandem duplicate 1
chr21_+_26657404 0.77 ENSDART00000129035
ENSDART00000186550
prdx5
peroxiredoxin 5
chr15_+_23799461 0.77 ENSDART00000154885
si:ch211-167j9.4
si:ch211-167j9.4
chr13_+_24662238 0.76 ENSDART00000014176
msx3
muscle segment homeobox 3
chr17_-_24680965 0.76 ENSDART00000154880
arhgef33
Rho guanine nucleotide exchange factor (GEF) 33
chr4_+_21129752 0.75 ENSDART00000169764
syt1a
synaptotagmin Ia
chr10_-_8033468 0.75 ENSDART00000140476
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr24_-_40700596 0.74 ENSDART00000162635
smyhc2
slow myosin heavy chain 2
chr23_+_44741500 0.74 ENSDART00000166421
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr23_-_7799184 0.74 ENSDART00000190946
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr5_-_14326959 0.73 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr20_+_37295006 0.73 ENSDART00000153137
cx23
connexin 23
chr9_+_21722733 0.73 ENSDART00000102021
sox1a
SRY (sex determining region Y)-box 1a
chr19_+_19786117 0.72 ENSDART00000167757
ENSDART00000163546
hoxa1a
homeobox A1a
chr24_+_25069609 0.71 ENSDART00000115165
amer2
APC membrane recruitment protein 2
chr22_-_6988102 0.71 ENSDART00000185618
fgfr1bl
fibroblast growth factor receptor 1b, like
chr3_-_28250722 0.71 ENSDART00000165936
rbfox1
RNA binding fox-1 homolog 1
chr19_+_19747430 0.70 ENSDART00000166129
hoxa9a
homeobox A9a
chr19_-_2318391 0.70 ENSDART00000012791
sp8a
sp8 transcription factor a
chr19_-_4010263 0.70 ENSDART00000159605
ENSDART00000165541
map7d1b
MAP7 domain containing 1b
chr21_-_28901095 0.70 ENSDART00000180820
cxxc5a
CXXC finger protein 5a
chr19_+_9786722 0.69 ENSDART00000138310
cacng6a
calcium channel, voltage-dependent, gamma subunit 6a
chr13_-_50108337 0.68 ENSDART00000133308
nid1a
nidogen 1a
chr2_+_25019387 0.68 ENSDART00000142601
stag1a
stromal antigen 1a
chr25_-_10503043 0.68 ENSDART00000155404
cox8b
cytochrome c oxidase subunit 8b
chr15_-_29598679 0.68 ENSDART00000155153
si:ch211-207n23.2
si:ch211-207n23.2
chr18_-_41375120 0.68 ENSDART00000098673
ptx3a
pentraxin 3, long a
chr20_-_39271844 0.67 ENSDART00000192708
clu
clusterin
chr15_-_34213898 0.66 ENSDART00000191945
ENSDART00000186089
etv1
ets variant 1
chr6_-_11780070 0.66 ENSDART00000151195
march7
membrane-associated ring finger (C3HC4) 7
chr4_+_12612145 0.66 ENSDART00000181201
lmo3
LIM domain only 3
chr10_+_26800213 0.66 ENSDART00000078996
arr3a
arrestin 3a, retinal (X-arrestin)
chr19_+_19762183 0.66 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr12_+_20352400 0.65 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr13_+_22480496 0.65 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr13_+_22479988 0.64 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr15_+_17752928 0.64 ENSDART00000155314
si:ch211-213d14.2
si:ch211-213d14.2
chr8_+_22582146 0.63 ENSDART00000157655
ENSDART00000189892
CT583651.2

chr20_+_2460864 0.63 ENSDART00000131642
akap7
A kinase (PRKA) anchor protein 7
chr7_+_28612671 0.62 ENSDART00000019991
slc7a6os
solute carrier family 7, member 6 opposite strand
chr13_+_19322686 0.62 ENSDART00000058036
emx2
empty spiracles homeobox 2
chr2_-_20599315 0.62 ENSDART00000114199
si:ch211-267e7.3
si:ch211-267e7.3
chr1_-_36152131 0.62 ENSDART00000182113
ENSDART00000182904
znf827
zinc finger protein 827
chr19_+_26718074 0.61 ENSDART00000134455
zgc:100906
zgc:100906
chr1_-_11973341 0.61 ENSDART00000159981
ENSDART00000066638
grk4
G protein-coupled receptor kinase 4
chr3_+_25154078 0.61 ENSDART00000156973
si:ch211-256m1.8
si:ch211-256m1.8
chr22_-_13851297 0.61 ENSDART00000080306
s100b
S100 calcium binding protein, beta (neural)
chr3_-_39695856 0.61 ENSDART00000148247
b9d1
B9 protein domain 1
chr13_-_6081803 0.60 ENSDART00000099224
dld
deltaD
chr5_-_25583125 0.60 ENSDART00000031665
ENSDART00000145353
anxa1a
annexin A1a
chr8_+_31821396 0.60 ENSDART00000077053
plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr9_+_6592710 0.60 ENSDART00000179893
fhl2a
four and a half LIM domains 2a
chr13_+_30912117 0.60 ENSDART00000133138
drgx
dorsal root ganglia homeobox
chr24_+_11334733 0.60 ENSDART00000147552
ENSDART00000143171
si:dkey-12l12.1
si:dkey-12l12.1
chr24_+_34606966 0.59 ENSDART00000105477
lrrtm2
leucine rich repeat transmembrane neuronal 2
chr16_+_32059785 0.59 ENSDART00000134459
si:dkey-40m6.8
si:dkey-40m6.8
chr2_-_10338759 0.58 ENSDART00000150166
ENSDART00000149584
gng12a
guanine nucleotide binding protein (G protein), gamma 12a
chr1_+_45085194 0.58 ENSDART00000193863
si:ch211-151p13.8
si:ch211-151p13.8
chr12_+_3022882 0.58 ENSDART00000122905
rac3b
Rac family small GTPase 3b
chr16_+_10422836 0.58 ENSDART00000161568
ino80e
INO80 complex subunit E
chr17_+_29276544 0.57 ENSDART00000049399
ankrd9
ankyrin repeat domain 9
chr6_-_19926657 0.57 ENSDART00000157527
ENSDART00000171384
ntn1a
netrin 1a
chr1_-_21723329 0.57 ENSDART00000137138
si:ch211-134c9.2
si:ch211-134c9.2
chr21_-_20341836 0.56 ENSDART00000176689
rbp4l
retinol binding protein 4, like
chr6_-_7720332 0.56 ENSDART00000135945
rpsa
ribosomal protein SA
chr14_-_33821515 0.55 ENSDART00000173218
vimr2
vimentin-related 2
chr13_+_29771463 0.55 ENSDART00000134424
ENSDART00000138332
ENSDART00000134330
ENSDART00000160944
ENSDART00000076992
ENSDART00000160921
pax2a
paired box 2a
chr12_+_25775734 0.55 ENSDART00000024415
ENSDART00000149198
epas1a
endothelial PAS domain protein 1a
chr7_+_32722227 0.55 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr14_-_33894915 0.55 ENSDART00000143290
urp1
urotensin-related peptide 1
chr23_-_5685023 0.55 ENSDART00000148680
ENSDART00000149365
tnnt2a
troponin T type 2a (cardiac)
chr14_+_49135264 0.54 ENSDART00000084119
si:ch1073-44g3.1
si:ch1073-44g3.1
chr2_+_22702488 0.54 ENSDART00000076647
kif1ab
kinesin family member 1Ab
chr20_-_47732703 0.54 ENSDART00000193975
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr17_+_38262408 0.54 ENSDART00000017493
nkx2.1
NK2 homeobox 1
chr13_+_23988442 0.54 ENSDART00000010918
agt
angiotensinogen
chr5_+_38913621 0.54 ENSDART00000137112
fras1
Fraser extracellular matrix complex subunit 1
chr17_-_12389259 0.54 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr8_+_23521974 0.54 ENSDART00000188130
ENSDART00000129378
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr3_-_36612877 0.54 ENSDART00000167164
si:dkeyp-72e1.7
si:dkeyp-72e1.7
chr9_-_1702648 0.53 ENSDART00000102934
hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
chr11_-_33960318 0.53 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr17_-_42213285 0.53 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr20_+_38031439 0.53 ENSDART00000153208
galnt14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr22_+_10066846 0.52 ENSDART00000105916
ENSDART00000105914
ENSDART00000132480
si:ch211-222k6.3
si:ch211-222k6.3
chr1_-_50859053 0.52 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr7_+_66565930 0.52 ENSDART00000154597
tmem176l.3b
transmembrane protein 176l.3b
chr13_+_24834199 0.52 ENSDART00000101274
zgc:153981
zgc:153981
chr6_+_52350443 0.52 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
si:ch211-239j9.1
chr13_-_43599898 0.52 ENSDART00000084416
ENSDART00000145705
ablim1a
actin binding LIM protein 1a
chr7_-_35083184 0.52 ENSDART00000100253
ENSDART00000135250
ENSDART00000173511
agrp
agouti related neuropeptide
chr24_-_14712427 0.52 ENSDART00000176316
jph1a
junctophilin 1a
chr5_+_11290851 0.52 ENSDART00000180408
CABZ01077124.1

chr13_+_38430466 0.51 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr7_-_28147838 0.51 ENSDART00000158921
lmo1
LIM domain only 1
chr10_+_37137464 0.51 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr5_-_12407194 0.51 ENSDART00000125291
ksr2
kinase suppressor of ras 2
chr16_+_9779680 0.51 ENSDART00000154253
zgc:92912
zgc:92912
chr4_+_31293362 0.50 ENSDART00000169781
si:dkey-57l19.1
si:dkey-57l19.1
chr5_+_15202495 0.50 ENSDART00000144915
tbx1
T-box 1
chr5_-_31901468 0.50 ENSDART00000147814
ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr20_-_23171430 0.50 ENSDART00000109234
spata18
spermatogenesis associated 18
chr4_+_12111154 0.50 ENSDART00000036779
tmem178b
transmembrane protein 178B
chr10_-_8032885 0.50 ENSDART00000188619
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr9_+_7724152 0.49 ENSDART00000061716
mnx2a
motor neuron and pancreas homeobox 2a
chr8_+_23738122 0.49 ENSDART00000062983
rpl10a
ribosomal protein L10a
chr12_+_16440708 0.48 ENSDART00000113810
ankrd1b
ankyrin repeat domain 1b (cardiac muscle)
chr16_-_383664 0.47 ENSDART00000051693
irx4a
iroquois homeobox 4a
chr6_+_25261297 0.47 ENSDART00000162824
ENSDART00000163490
ENSDART00000157790
ENSDART00000160978
ENSDART00000161545
ENSDART00000159978
kyat3
kynurenine aminotransferase 3
chr19_+_19775757 0.46 ENSDART00000164677
hoxa3a
homeobox A3a
chr21_-_20757866 0.46 ENSDART00000163003
ghrb
growth hormone receptor b
chr20_+_33875256 0.46 ENSDART00000002554
rxrgb
retinoid X receptor, gamma b
chr3_-_35800221 0.46 ENSDART00000031390
caskin1
CASK interacting protein 1
chr10_+_35439952 0.46 ENSDART00000006284
hhla2a.2
HERV-H LTR-associating 2a, tandem duplicate 2
chr18_+_24921587 0.46 ENSDART00000191345
rgma
repulsive guidance molecule family member a
chr16_-_6391275 0.46 ENSDART00000060550
ndufb9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.3+nkx2.7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.5 2.5 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.4 1.3 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.4 1.1 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.4 1.4 GO:2000252 positive regulation of epithelial cell differentiation(GO:0030858) negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.3 1.7 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.3 1.1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.3 0.8 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 0.8 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 1.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 1.0 GO:0015871 choline transport(GO:0015871)
0.2 1.0 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.2 1.5 GO:0021767 mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.2 0.9 GO:0045988 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.2 1.4 GO:0060017 parathyroid gland development(GO:0060017)
0.2 0.6 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.2 0.9 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.2 0.9 GO:0061551 trigeminal ganglion development(GO:0061551)
0.2 0.7 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 0.5 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.2 0.9 GO:0061323 cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136)
0.2 0.5 GO:0008343 adult feeding behavior(GO:0008343)
0.2 0.6 GO:0044003 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.2 1.2 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.9 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 2.5 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.7 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.4 GO:0007414 axonal defasciculation(GO:0007414)
0.1 1.1 GO:0043584 nose development(GO:0043584)
0.1 1.2 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 0.8 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 1.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.3 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.1 0.3 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 0.7 GO:0048069 eye pigmentation(GO:0048069)
0.1 1.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.7 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1 0.3 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.1 0.4 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.3 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.1 0.5 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.6 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.1 0.6 GO:0032623 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.8 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.2 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 3.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.3 GO:0010259 multicellular organism aging(GO:0010259)
0.1 0.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.4 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.1 0.4 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.2 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 1.2 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 0.3 GO:0097066 response to thyroid hormone(GO:0097066)
0.1 0.4 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.7 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 2.3 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.2 GO:0014823 response to activity(GO:0014823)
0.1 0.8 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 1.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 1.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.1 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 1.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.2 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.1 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.5 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 1.2 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.1 0.2 GO:0043383 chemokine production(GO:0032602) negative T cell selection(GO:0043383) thymocyte migration(GO:0072679)
0.1 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.4 GO:0021561 facial nerve development(GO:0021561)
0.0 0.3 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.6 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 1.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.5 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.7 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0034138 toll-like receptor 3 signaling pathway(GO:0034138)
0.0 0.5 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.0 0.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.7 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 1.0 GO:0043049 otic placode formation(GO:0043049)
0.0 0.5 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 1.2 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.2 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.0 0.6 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 1.2 GO:0044259 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.0 0.6 GO:0021654 rhombomere boundary formation(GO:0021654)
0.0 0.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 3.1 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.6 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.2 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.2 GO:0019405 alditol catabolic process(GO:0019405)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.0 0.2 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0070293 renal absorption(GO:0070293)
0.0 0.6 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 1.0 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.4 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 1.3 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.6 GO:0048794 swim bladder development(GO:0048794)
0.0 0.4 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.3 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 2.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.0 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.7 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.2 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 2.4 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.6 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.4 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.1 GO:0019627 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.0 0.1 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.5 GO:0071711 epithelial structure maintenance(GO:0010669) basement membrane organization(GO:0071711)
0.0 0.4 GO:0007254 JNK cascade(GO:0007254)
0.0 0.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0060004 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 2.2 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.4 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 1.1 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.5 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0031673 H zone(GO:0031673)
0.2 1.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.5 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 4.1 GO:0005861 troponin complex(GO:0005861)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.7 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.7 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 2.2 GO:0043679 axon terminus(GO:0043679)
0.1 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.4 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 4.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 1.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 1.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 2.6 GO:0005882 intermediate filament(GO:0005882)
0.0 1.3 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.7 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 2.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.4 1.2 GO:1903136 cuprous ion binding(GO:1903136)
0.4 2.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 1.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 1.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 1.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.2 1.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 1.0 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 0.6 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.0 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 1.0 GO:0034632 retinol transporter activity(GO:0034632)
0.1 0.5 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.8 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.6 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.5 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 1.1 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.3 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 1.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.3 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
0.1 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.8 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 0.3 GO:0004771 sterol esterase activity(GO:0004771)
0.1 1.2 GO:0051117 ATPase binding(GO:0051117)
0.1 0.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.2 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 1.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.6 GO:0031720 haptoglobin binding(GO:0031720)
0.1 1.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.9 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 2.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0043295 glutathione binding(GO:0043295)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 3.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.3 GO:0008009 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 2.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.2 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0015145 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 0.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling