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PRJNA195909:zebrafish embryo and larva development

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Results for nkx3-1

Z-value: 1.90

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Transcription factors associated with nkx3-1

Gene Symbol Gene ID Gene Info
nkx3-1
ENSDARG00000078280 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx3-1dr11_v1_chr8_-_50259448_50259448-0.761.8e-02Click!

Activity profile of nkx3-1 motif

Sorted Z-values of nkx3-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_34915886 6.23 ENSDART00000141201
ENSDART00000002166
ccna1
cyclin A1
chr22_+_25236657 5.75 ENSDART00000138012
zgc:172218
zgc:172218
chr22_+_25249193 5.64 ENSDART00000171851
si:ch211-226h8.11
si:ch211-226h8.11
chr9_+_8396755 5.30 ENSDART00000043067
zgc:171776
zgc:171776
chr10_-_34916208 5.29 ENSDART00000187371
ccna1
cyclin A1
chr9_+_44994214 4.08 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr7_+_17947217 3.71 ENSDART00000101601
cth1
cysteine three histidine 1
chr16_+_54641230 3.50 ENSDART00000157641
ENSDART00000159540
fbxo43
F-box protein 43
chr15_+_29025090 2.91 ENSDART00000131755
si:ch211-137a8.2
si:ch211-137a8.2
chr9_-_12888082 2.83 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr9_-_8296723 2.73 ENSDART00000139867
si:ch211-145c1.1
si:ch211-145c1.1
chr19_-_47587719 2.64 ENSDART00000111108
CABZ01071972.1

chr10_+_585719 2.47 ENSDART00000180167
smad4a
SMAD family member 4a
chr4_+_3312852 2.33 ENSDART00000084691
fgd4b
FYVE, RhoGEF and PH domain containing 4b
chr17_+_10578823 2.05 ENSDART00000134610
mgaa
MGA, MAX dimerization protein a
chr1_-_55248496 1.96 ENSDART00000098615
nanos3
nanos homolog 3
chr19_+_32401278 1.90 ENSDART00000184353
atxn1a
ataxin 1a
chr25_-_24240797 1.86 ENSDART00000132790
spty2d1
SPT2 chromatin protein domain containing 1
chr6_-_8465656 1.86 ENSDART00000178887
si:dkey-217d24.6
si:dkey-217d24.6
chr14_+_14806851 1.86 ENSDART00000169235
fhdc2
FH2 domain containing 2
chr17_-_43623356 1.82 ENSDART00000075596
ENSDART00000136431
rtkn2a
rhotekin 2a
chr9_+_22632126 1.82 ENSDART00000139434
etv5a
ets variant 5a
chr5_+_16117871 1.82 ENSDART00000090657
znrf3
zinc and ring finger 3
chr15_+_25452092 1.80 ENSDART00000009545
pak4
p21 protein (Cdc42/Rac)-activated kinase 4
chr12_+_31460877 1.73 ENSDART00000031154
gucy2g
guanylate cyclase 2g
chr4_-_46648979 1.66 ENSDART00000162101
BX927193.2

chr2_+_50477779 1.65 ENSDART00000122716
CABZ01067973.1

chr19_-_10330778 1.64 ENSDART00000081465
ENSDART00000136653
ENSDART00000171232
ccdc106b
coiled-coil domain containing 106b
chr19_-_31707892 1.62 ENSDART00000088427
ripor2
RHO family interacting cell polarization regulator 2
chr7_+_10911396 1.61 ENSDART00000167273
ENSDART00000081323
ENSDART00000170655
abhd17c
abhydrolase domain containing 17C
chr5_+_36666715 1.61 ENSDART00000097686
zgc:153990
zgc:153990
chr19_+_33139164 1.60 ENSDART00000043039
fam84b
family with sequence similarity 84, member B
chr16_-_42175617 1.58 ENSDART00000084715
alkbh8
alkB homolog 8, tRNA methyltransferase
chr16_-_41535690 1.54 ENSDART00000102662
rpp25l
ribonuclease P/MRP 25 subunit-like
chr3_-_26805455 1.53 ENSDART00000180648
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr23_+_27782071 1.50 ENSDART00000131379
kmt2d
lysine (K)-specific methyltransferase 2D
chr19_+_4051695 1.48 ENSDART00000166368
btr24
bloodthirsty-related gene family, member 24
chr2_+_45696743 1.47 ENSDART00000114225
ENSDART00000169279
CU467828.1

chr5_+_18012154 1.46 ENSDART00000139431
ENSDART00000048859
ascc2
activating signal cointegrator 1 complex subunit 2
chr19_+_7424347 1.45 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr21_+_18907102 1.45 ENSDART00000160185
ENSDART00000190175
ENSDART00000017937
ENSDART00000191546
ENSDART00000130519
ENSDART00000137143
smpd4
sphingomyelin phosphodiesterase 4
chr5_-_10082244 1.45 ENSDART00000036421
chek2
checkpoint kinase 2
chr1_-_51261420 1.43 ENSDART00000168685
kif16ba
kinesin family member 16Ba
chr7_-_64770456 1.43 ENSDART00000192618
zdhhc21
zinc finger, DHHC-type containing 21
chr20_-_18535502 1.40 ENSDART00000049437
cdc42bpb
CDC42 binding protein kinase beta (DMPK-like)
chr5_+_30596477 1.39 ENSDART00000124487
hinfp
histone H4 transcription factor
chr5_-_23473312 1.39 ENSDART00000140310
si:dkeyp-20g2.3
si:dkeyp-20g2.3
chr4_-_4570475 1.38 ENSDART00000184955
rassf3
Ras association (RalGDS/AF-6) domain family member 3
chr5_-_16475374 1.38 ENSDART00000134274
ENSDART00000136004
piwil2
piwi-like RNA-mediated gene silencing 2
chr10_-_3258073 1.36 ENSDART00000113162
pi4kaa
phosphatidylinositol 4-kinase, catalytic, alpha a
chr14_+_8715527 1.36 ENSDART00000170754
kcnk4a
potassium channel, subfamily K, member 4a
chr6_-_19351495 1.35 ENSDART00000164287
grb2a
growth factor receptor-bound protein 2a
chr14_+_14806692 1.35 ENSDART00000193050
fhdc2
FH2 domain containing 2
chr4_-_65323874 1.35 ENSDART00000175271
ENSDART00000187913
BX571813.1

chr5_+_30596632 1.35 ENSDART00000051414
hinfp
histone H4 transcription factor
chr8_-_22326073 1.34 ENSDART00000084965
cep104
centrosomal protein 104
chr12_-_31461219 1.34 ENSDART00000148954
acsl5
acyl-CoA synthetase long chain family member 5
chr1_+_44056129 1.32 ENSDART00000161114
CU915778.1

chr2_-_10877228 1.31 ENSDART00000138718
ENSDART00000034246
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr17_+_43623598 1.31 ENSDART00000154138
znf365
zinc finger protein 365
chr5_-_23795688 1.31 ENSDART00000099084
gbgt1l4
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
chr5_-_16475682 1.30 ENSDART00000090695
piwil2
piwi-like RNA-mediated gene silencing 2
chr6_-_49537646 1.28 ENSDART00000180438
FO704848.1

chr9_-_46072805 1.28 ENSDART00000169682
hdac4
histone deacetylase 4
chr7_-_58178980 1.27 ENSDART00000073635
nsmaf
neutral sphingomyelinase (N-SMase) activation associated factor
chr11_+_25157374 1.27 ENSDART00000019450
trpc4apa
transient receptor potential cation channel, subfamily C, member 4 associated protein a
chr11_+_30636351 1.26 ENSDART00000087909
tmem246
transmembrane protein 246
chr5_+_27137473 1.24 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr21_-_14174786 1.24 ENSDART00000145366
whrna
whirlin a
chr25_+_34862225 1.24 ENSDART00000149782
CHST6
zgc:194879
chr19_-_3821678 1.24 ENSDART00000169639
si:dkey-206d17.12
si:dkey-206d17.12
chr1_-_354115 1.24 ENSDART00000141590
ENSDART00000098627
pros1
protein S
chr12_-_6818676 1.23 ENSDART00000106391
pcdh15b
protocadherin-related 15b
chr9_-_50001606 1.23 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr3_+_32389904 1.22 ENSDART00000154788
ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr3_-_18189283 1.21 ENSDART00000049240
tob1a
transducer of ERBB2, 1a
chr12_+_23850661 1.21 ENSDART00000152921
svila
supervillin a
chr21_-_11286483 1.20 ENSDART00000074845
rtkn2b
rhotekin 2b
chr7_-_26532089 1.20 ENSDART00000121698
senp3b
SUMO1/sentrin/SMT3 specific peptidase 3b
chr23_-_36592436 1.19 ENSDART00000168246
spryd3
SPRY domain containing 3
chr2_-_7757273 1.19 ENSDART00000136074
b3gnt5b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5b
chr4_+_74928675 1.18 ENSDART00000192755
nup50
nucleoporin 50
chr4_-_36793658 1.18 ENSDART00000172152
si:dkeyp-87d1.1
si:dkeyp-87d1.1
chr24_-_26518972 1.18 ENSDART00000097792
tnikb
TRAF2 and NCK interacting kinase b
chr19_+_22085925 1.18 ENSDART00000185636
atp9b
ATPase phospholipid transporting 9B
chr9_-_51563575 1.17 ENSDART00000167034
ENSDART00000148918
tank
TRAF family member-associated NFKB activator
chr19_-_4851411 1.16 ENSDART00000110398
fbxl20
F-box and leucine-rich repeat protein 20
chr12_+_32729470 1.16 ENSDART00000175712
rbfox3a
RNA binding fox-1 homolog 3a
chr16_+_16253710 1.15 ENSDART00000137672
setd2
SET domain containing 2
chr5_-_57204352 1.15 ENSDART00000171252
ENSDART00000180727
man2a1
mannosidase, alpha, class 2A, member 1
chr3_+_36222799 1.14 ENSDART00000113105
dus1l
dihydrouridine synthase 1-like (S. cerevisiae)
chr2_+_10642047 1.14 ENSDART00000091570
fam69aa
family with sequence similarity 69, member Aa
chr3_-_31875138 1.13 ENSDART00000155298
limd2
LIM domain containing 2
chr12_-_33579873 1.12 ENSDART00000184661
tdrkh
tudor and KH domain containing
chr3_-_15668433 1.10 ENSDART00000115022
zgc:66474
zgc:66474
chr17_+_6538733 1.10 ENSDART00000193712
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr21_+_19547806 1.09 ENSDART00000159707
ENSDART00000184869
ENSDART00000181321
ENSDART00000058487
ENSDART00000058485
rai14
retinoic acid induced 14
chr3_-_36420397 1.09 ENSDART00000167896
cog1
component of oligomeric golgi complex 1
chr17_-_24703778 1.09 ENSDART00000156061
si:ch211-15d5.12
si:ch211-15d5.12
chr4_+_40018440 1.08 ENSDART00000110827
si:dkey-199k11.6
si:dkey-199k11.6
chr24_+_30521619 1.08 ENSDART00000162903
dpyda.3
dihydropyrimidine dehydrogenase a, tandem duplicate 3
chr14_+_50937757 1.08 ENSDART00000163865
rnf44
ring finger protein 44
chr3_-_36419641 1.07 ENSDART00000173545
cog1
component of oligomeric golgi complex 1
chr9_-_14273652 1.07 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr4_-_66843599 1.06 ENSDART00000181654
BX649556.2

chr2_+_15100742 1.05 ENSDART00000027171
f3b
coagulation factor IIIb
chr13_-_36680531 1.05 ENSDART00000085298
l2hgdh
L-2-hydroxyglutarate dehydrogenase
chr12_-_10476448 1.05 ENSDART00000106172
rac1a
Rac family small GTPase 1a
chr13_-_32726178 1.04 ENSDART00000012232
pdss2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr14_+_28281744 1.04 ENSDART00000173292
mid2
midline 2
chr21_-_14815952 1.03 ENSDART00000134278
ENSDART00000067004
phpt1
phosphohistidine phosphatase 1
chr9_+_28140089 1.03 ENSDART00000046880
plekhm3
pleckstrin homology domain containing, family M, member 3
chr5_-_23464970 1.02 ENSDART00000141028
si:dkeyp-20g2.1
si:dkeyp-20g2.1
chr20_-_6184167 1.01 ENSDART00000147451
b4galt6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr6_+_10338554 1.01 ENSDART00000186936
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr21_-_2042037 1.01 ENSDART00000171131
ENSDART00000160144
add1
adducin 1 (alpha)
chr10_+_3153973 1.01 ENSDART00000183223
hic2
hypermethylated in cancer 2
chr16_-_42238120 1.00 ENSDART00000084730
zgc:162160
zgc:162160
chr17_+_13664442 1.00 ENSDART00000171689
lrfn5a
leucine rich repeat and fibronectin type III domain containing 5a
chr25_-_13403726 0.98 ENSDART00000056723
gins3
GINS complex subunit 3
chr24_+_26406770 0.98 ENSDART00000110011
si:ch211-230g15.5
si:ch211-230g15.5
chr10_+_44373349 0.98 ENSDART00000172191
snrnp35
small nuclear ribonucleoprotein 35 (U11/U12)
chr9_+_48123002 0.98 ENSDART00000099794
ENSDART00000169733
klhl23
kelch-like family member 23
chr2_+_11031360 0.98 ENSDART00000180020
ENSDART00000145093
acot11a
acyl-CoA thioesterase 11a
chr4_-_77252368 0.98 ENSDART00000111941
zgc:174310
zgc:174310
chr14_-_33978117 0.98 ENSDART00000128515
foxa
forkhead box A sequence
chr11_+_41540862 0.98 ENSDART00000173210
kcnab2a
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr11_-_23697217 0.96 ENSDART00000124810
pik3c2b
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr4_+_69801372 0.95 ENSDART00000154125
si:dkey-238o14.7
si:dkey-238o14.7
chr3_+_25849560 0.95 ENSDART00000007119
mfsd6l
major facilitator superfamily domain containing 6-like
chr9_+_48123224 0.94 ENSDART00000141610
klhl23
kelch-like family member 23
chr17_+_30894431 0.93 ENSDART00000127996
degs2
delta(4)-desaturase, sphingolipid 2
chr17_+_6765621 0.93 ENSDART00000156637
ENSDART00000007622
afg1la
AFG1 like ATPase a
chr7_-_26627252 0.91 ENSDART00000164050
ENSDART00000159826
phf23b
PHD finger protein 23b
chr24_+_26328787 0.91 ENSDART00000003884
mynn
myoneurin
chr14_-_31814149 0.90 ENSDART00000173393
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr20_-_25902141 0.89 ENSDART00000142611
ENSDART00000024821
elmsan1a
ELM2 and Myb/SANT-like domain containing 1a
chr17_+_52612866 0.89 ENSDART00000182828
ENSDART00000191156
ENSDART00000188814
ENSDART00000109891
angel1
angel homolog 1 (Drosophila)
chr20_+_46620374 0.89 ENSDART00000005548
batf
basic leucine zipper transcription factor, ATF-like
chr20_-_9194257 0.86 ENSDART00000133012
ylpm1
YLP motif containing 1
chr25_+_34749187 0.85 ENSDART00000141473
wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr8_-_20862443 0.85 ENSDART00000147267
si:ch211-133l5.8
si:ch211-133l5.8
chr20_-_13625588 0.82 ENSDART00000078893
sytl3
synaptotagmin-like 3
chr12_+_33361948 0.82 ENSDART00000124982
fasn
fatty acid synthase
chr6_+_9981300 0.81 ENSDART00000151482
abi2b
abl-interactor 2b
chr17_-_1705013 0.79 ENSDART00000182864
CABZ01086293.1

chr17_-_43031763 0.79 ENSDART00000132754
ENSDART00000050399
npc2
Niemann-Pick disease, type C2
chr2_-_10641998 0.78 ENSDART00000188323
mtf2
metal response element binding transcription factor 2
chr17_-_18898115 0.78 ENSDART00000028044
galcb
galactosylceramidase b
chr3_-_26806032 0.78 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr8_-_11202378 0.77 ENSDART00000147817
ENSDART00000174039
fam208b
family with sequence similarity 208, member B
chr14_+_556501 0.76 ENSDART00000181289
nudt6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr2_-_29923630 0.75 ENSDART00000158844
ENSDART00000031130
paxip1
PAX interacting (with transcription-activation domain) protein 1
chr5_+_5406503 0.74 ENSDART00000124022
mapkap1
mitogen-activated protein kinase associated protein 1
chr12_-_25150239 0.73 ENSDART00000038415
ENSDART00000135368
rhoq
ras homolog family member Q
chr14_-_48786708 0.73 ENSDART00000169730
si:ch211-199b20.3
si:ch211-199b20.3
chr7_+_41322407 0.72 ENSDART00000114076
ENSDART00000139093
dph2
DPH2 homolog (S. cerevisiae)
chr3_-_27915270 0.72 ENSDART00000115370
mettl22
methyltransferase like 22
chr25_+_8662469 0.71 ENSDART00000154680
ENSDART00000188568
man2a2
mannosidase, alpha, class 2A, member 2
chr18_+_6558338 0.71 ENSDART00000110892
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr4_+_76466751 0.69 ENSDART00000164709
zgc:153116
zgc:153116
chr7_+_37742299 0.69 ENSDART00000143300
brd7
bromodomain containing 7
chr9_-_32804953 0.69 ENSDART00000134763
zgc:112056
zgc:112056
chr7_+_58179513 0.69 ENSDART00000123117
ggh
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr22_+_2144278 0.68 ENSDART00000162173
ENSDART00000159914
ENSDART00000160192
znf1164
zinc finger protein 1164
chr8_-_16675464 0.68 ENSDART00000191982
osbpl9
oxysterol binding protein-like 9
chr9_+_35015747 0.67 ENSDART00000140110
gabpa
GA binding protein transcription factor, alpha subunit
chr15_-_28805493 0.67 ENSDART00000179617
cd3eap
CD3e molecule, epsilon associated protein
chr14_+_35013656 0.66 ENSDART00000164974
ebf3a
early B cell factor 3a
chr21_+_37090585 0.66 ENSDART00000182971
znf346
zinc finger protein 346
chr11_+_2649891 0.66 ENSDART00000093052
si:ch211-160o17.4
si:ch211-160o17.4
chr4_-_16706776 0.65 ENSDART00000079461
dennd5b
DENN/MADD domain containing 5B
chr19_-_18152942 0.65 ENSDART00000190182
nfe2l3
nuclear factor, erythroid 2-like 3
chr25_-_34973211 0.64 ENSDART00000045177
cdk10
cyclin-dependent kinase 10
chr9_+_2522797 0.64 ENSDART00000186786
ENSDART00000147034
gpr155a
G protein-coupled receptor 155a
chr21_-_35325466 0.63 ENSDART00000134780
ENSDART00000145930
ENSDART00000076715
ENSDART00000065341
ENSDART00000162189
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr24_+_26017094 0.62 ENSDART00000137851
tfr1b
transferrin receptor 1b
chr22_+_2685883 0.62 ENSDART00000131741
si:dkey-20i20.15
si:dkey-20i20.15
chr22_-_29906764 0.61 ENSDART00000019786
smc3
structural maintenance of chromosomes 3
chr21_+_37090795 0.61 ENSDART00000085786
znf346
zinc finger protein 346
chr11_+_2649664 0.60 ENSDART00000166357
si:ch211-160o17.4
si:ch211-160o17.4
chr3_+_11548516 0.59 ENSDART00000059117
mmd
monocyte to macrophage differentiation-associated
chr7_-_32875552 0.59 ENSDART00000132504
ano5b
anoctamin 5b
chr5_+_41143563 0.59 ENSDART00000011229
sub1b
SUB1 homolog, transcriptional regulator b
chr23_-_40295610 0.58 ENSDART00000186719
CABZ01067002.1

chr15_+_17848590 0.58 ENSDART00000168940
zgc:113279
zgc:113279
chr20_-_38525467 0.57 ENSDART00000061417
si:ch211-245h14.1
si:ch211-245h14.1
chr18_-_12416019 0.57 ENSDART00000144799
si:ch211-1e14.1
si:ch211-1e14.1
chr19_-_18152407 0.57 ENSDART00000193264
ENSDART00000016135
nfe2l3
nuclear factor, erythroid 2-like 3
chr8_+_46939391 0.57 ENSDART00000146631
espn
espin
chr24_+_14595680 0.56 ENSDART00000137337
ENSDART00000091784
ENSDART00000136026
thtpa
thiamine triphosphatase
chr6_+_32834007 0.56 ENSDART00000157353
cyldl
cylindromatosis (turban tumor syndrome), like
chr9_+_50599362 0.55 ENSDART00000023105
fign
fidgetin
chr15_-_24676211 0.55 ENSDART00000153502
ENSDART00000100756
tmem199
transmembrane protein 199
chr5_-_25576462 0.54 ENSDART00000165147
si:dkey-229d2.4
si:dkey-229d2.4
chr8_+_46939566 0.54 ENSDART00000139422
espn
espin
chr7_+_31132588 0.53 ENSDART00000173702
tjp1a
tight junction protein 1a
chr15_-_1844048 0.53 ENSDART00000102410
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_-_55752169 0.53 ENSDART00000097424
kcmf1
potassium channel modulatory factor 1
chr14_+_52440161 0.52 ENSDART00000168437
b4galt1l
DP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, like

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx3-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.6 1.9 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.5 1.6 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.5 1.8 GO:0032801 receptor catabolic process(GO:0032801)
0.4 1.3 GO:2000191 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.4 3.5 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.4 1.3 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.4 1.2 GO:0042730 fibrinolysis(GO:0042730)
0.3 1.0 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.3 1.0 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.3 1.3 GO:0090299 regulation of neural crest formation(GO:0090299)
0.3 1.9 GO:0006013 mannose metabolic process(GO:0006013)
0.3 1.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.3 1.1 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.3 1.1 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.2 2.4 GO:0006611 protein export from nucleus(GO:0006611)
0.2 1.1 GO:0019482 uracil catabolic process(GO:0006212) beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483) uracil metabolic process(GO:0019860) 'de novo' UMP biosynthetic process(GO:0044205)
0.2 1.2 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.2 0.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 1.8 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.2 9.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.2 0.7 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 1.2 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.2 1.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 1.5 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.2 0.6 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 0.4 GO:0034214 protein hexamerization(GO:0034214)
0.1 4.5 GO:0048264 determination of ventral identity(GO:0048264)
0.1 1.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.0 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.8 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.1 0.9 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.6 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.7 GO:0090134 establishment or maintenance of cytoskeleton polarity(GO:0030952) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.7 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 1.1 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.6 GO:0016572 histone phosphorylation(GO:0016572)
0.1 1.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.6 GO:0003272 endocardial cushion formation(GO:0003272)
0.1 0.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.6 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1 0.4 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 1.0 GO:0098900 regulation of action potential(GO:0098900)
0.1 1.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.4 GO:0039689 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.1 0.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 1.3 GO:0030259 lipid glycosylation(GO:0030259)
0.1 1.2 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.6 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 2.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.3 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.9 GO:0034311 diol metabolic process(GO:0034311)
0.1 0.4 GO:0051883 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.1 1.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 2.3 GO:0046847 filopodium assembly(GO:0046847)
0.1 1.4 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.1 0.6 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 1.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.0 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 1.0 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:0036314 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.9 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 1.0 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 1.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 1.2 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.4 GO:0035141 medial fin morphogenesis(GO:0035141)
0.0 1.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.3 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.4 GO:0071174 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174) negative regulation of metaphase/anaphase transition of cell cycle(GO:1902100)
0.0 0.4 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 1.3 GO:0021545 cranial nerve development(GO:0021545)
0.0 1.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.5 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.2 GO:0001845 phagolysosome assembly(GO:0001845)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.2 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.0 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.5 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.5 2.7 GO:1990923 PET complex(GO:1990923)
0.4 1.6 GO:0060171 stereocilium membrane(GO:0060171)
0.4 2.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 1.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 1.0 GO:0000811 GINS complex(GO:0000811)
0.2 1.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 1.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.2 GO:0017119 Golgi transport complex(GO:0017119)
0.2 2.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 2.5 GO:0032420 stereocilium(GO:0032420)
0.1 3.1 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 2.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.0 GO:0043186 P granule(GO:0043186)
0.1 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.6 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 1.1 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.0 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 1.3 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.0 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 1.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.6 GO:0030027 lamellipodium(GO:0030027)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.3 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 1.4 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.0 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.4 1.3 GO:0030882 lipid antigen binding(GO:0030882)
0.4 1.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.4 1.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.4 2.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.4 1.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 1.0 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.3 2.7 GO:0034584 piRNA binding(GO:0034584)
0.3 1.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 1.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.3 1.0 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.2 0.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 1.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 1.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.2 0.6 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.8 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 9.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.7 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 1.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.6 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 1.1 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.9 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.4 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 1.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.2 GO:0000996 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 1.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 18.3 GO:0030246 carbohydrate binding(GO:0030246)
0.1 0.5 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 1.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.4 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.0 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.0 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.8 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 1.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.0 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 2.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 1.0 GO:0017069 snRNA binding(GO:0017069)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.2 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.1 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462)
0.0 1.3 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0072570 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.1 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 3.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 11.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.1 PID ATM PATHWAY ATM pathway
0.1 1.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 11.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 1.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 1.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 1.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.8 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 2.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 2.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.4 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 1.2 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.0 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling