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PRJNA195909:zebrafish embryo and larva development

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Results for nkx6.1

Z-value: 0.68

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Transcription factors associated with nkx6.1

Gene Symbol Gene ID Gene Info
nkx6.1
ENSDARG00000022569 NK6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx6.1dr11_v1_chr21_+_19070921_190709210.019.8e-01Click!

Activity profile of nkx6.1 motif

Sorted Z-values of nkx6.1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_30244356 1.21 ENSDART00000036050
ENSDART00000150080
rs1a
retinoschisin 1a
chr1_-_43905252 0.79 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
si:dkey-22i16.3
chr7_+_14291323 0.58 ENSDART00000053521
rhcga
Rh family, C glycoprotein a
chr25_+_29160102 0.56 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr3_-_50443607 0.47 ENSDART00000074036
rcvrna
recoverin a
chr16_+_46111849 0.46 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr5_-_30620625 0.44 ENSDART00000098273
tcnl
transcobalamin like
chr20_-_40755614 0.41 ENSDART00000061247
cx32.3
connexin 32.3
chr17_+_15433671 0.39 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr2_-_27329214 0.39 ENSDART00000145835
tmx3a
thioredoxin related transmembrane protein 3a
chr17_+_15433518 0.39 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr5_-_23362602 0.37 ENSDART00000137120
gria3a
glutamate receptor, ionotropic, AMPA 3a
chr12_-_35054354 0.35 ENSDART00000075351
zgc:112285
zgc:112285
chr16_+_23431189 0.35 ENSDART00000004679
icn
ictacalcin
chr2_+_37227011 0.35 ENSDART00000126587
ENSDART00000084958
samd7
sterile alpha motif domain containing 7
chr7_-_28148310 0.33 ENSDART00000044208
lmo1
LIM domain only 1
chr18_+_46773198 0.33 ENSDART00000174647
CABZ01041495.1

chr5_-_44829719 0.32 ENSDART00000019104
fbp2
fructose-1,6-bisphosphatase 2
chr19_+_10339538 0.31 ENSDART00000151808
ENSDART00000151235
rcvrn3
recoverin 3
chr14_+_49135264 0.30 ENSDART00000084119
si:ch1073-44g3.1
si:ch1073-44g3.1
chr10_+_22381802 0.29 ENSDART00000112484
nlgn2b
neuroligin 2b
chr12_+_24342303 0.28 ENSDART00000111239
nrxn1a
neurexin 1a
chr13_+_29462249 0.28 ENSDART00000147903
lrit1a
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1a
chr23_+_40460333 0.27 ENSDART00000184658
soga3b
SOGA family member 3b
chr16_-_45178430 0.26 ENSDART00000165186
si:dkey-33i11.9
si:dkey-33i11.9
chr3_+_23092762 0.25 ENSDART00000142884
ENSDART00000024136
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr1_-_43915423 0.25 ENSDART00000181915
ENSDART00000113673
scpp5
secretory calcium-binding phosphoprotein 5
chr20_+_18551657 0.25 ENSDART00000147001
si:dkeyp-72h1.1
si:dkeyp-72h1.1
chr1_-_22512063 0.24 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr16_+_23913943 0.23 ENSDART00000175404
ENSDART00000129525
apoa4b.1
apolipoprotein A-IV b, tandem duplicate 1
chr12_+_5081759 0.23 ENSDART00000164178
prrt2
proline-rich transmembrane protein 2
chr5_-_38155005 0.23 ENSDART00000097770
gucy2d
guanylate cyclase 2D, retinal
chr13_+_23988442 0.23 ENSDART00000010918
agt
angiotensinogen
chr22_+_28320792 0.22 ENSDART00000160562
ENSDART00000164138
impg2b
impg2b
interphotoreceptor matrix proteoglycan 2b
interphotoreceptor matrix proteoglycan 2b
chr14_+_50770537 0.22 ENSDART00000158723
sncb
synuclein, beta
chr19_+_32166702 0.22 ENSDART00000021798
fabp11a
fatty acid binding protein 11a
chr21_+_6780340 0.22 ENSDART00000139493
ENSDART00000140478
olfm1b
olfactomedin 1b
chr13_+_38430466 0.22 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr25_+_3058924 0.22 ENSDART00000029580
fth1b
ferritin, heavy polypeptide 1b
chr7_-_24699985 0.22 ENSDART00000052802
calb2b
calbindin 2b
chr15_+_22311803 0.21 ENSDART00000150182
hepacama
hepatic and glial cell adhesion molecule a
chr8_-_34052019 0.21 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr5_-_43071058 0.21 ENSDART00000165546
si:dkey-245n4.2
si:dkey-245n4.2
chr3_-_41791178 0.21 ENSDART00000049687
grifin
galectin-related inter-fiber protein
chr17_-_12389259 0.21 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr3_-_28258462 0.20 ENSDART00000191573
rbfox1
RNA binding fox-1 homolog 1
chr22_-_13042992 0.20 ENSDART00000028787
ahr1b
aryl hydrocarbon receptor 1b
chr14_-_2933185 0.20 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr21_-_22827548 0.20 ENSDART00000079161
angptl5
angiopoietin-like 5
chr8_-_25120231 0.20 ENSDART00000147308
amigo1
adhesion molecule with Ig-like domain 1
chr13_-_30700460 0.19 ENSDART00000139073
rassf4
Ras association (RalGDS/AF-6) domain family member 4
chr7_-_28147838 0.19 ENSDART00000158921
lmo1
LIM domain only 1
chr9_+_34641237 0.19 ENSDART00000133996
shox
short stature homeobox
chr21_-_42100471 0.19 ENSDART00000166148
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr10_+_25726694 0.19 ENSDART00000140308
ugt5d1
UDP glucuronosyltransferase 5 family, polypeptide D1
chr20_-_27711970 0.19 ENSDART00000139637
zbtb25
zinc finger and BTB domain containing 25
chr3_+_28953274 0.19 ENSDART00000133528
ENSDART00000103602
lgals2a
lectin, galactoside-binding, soluble, 2a
chr5_+_63668735 0.18 ENSDART00000134261
ENSDART00000097330
dnm1b
dynamin 1b
chr6_-_37469775 0.18 ENSDART00000156546
plcxd1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr17_-_16965809 0.18 ENSDART00000153697
nrxn3a
neurexin 3a
chr1_-_50859053 0.18 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr6_-_35779348 0.18 ENSDART00000191159
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr4_+_21129752 0.18 ENSDART00000169764
syt1a
synaptotagmin Ia
chr12_+_18681477 0.18 ENSDART00000127981
ENSDART00000143979
rgs9b
regulator of G protein signaling 9b
chr14_-_4556896 0.18 ENSDART00000044678
ENSDART00000192863
GABRA2
gamma-aminobutyric acid type A receptor alpha2 subunit
chr23_-_10175898 0.18 ENSDART00000146185
krt5
keratin 5
chr22_+_12770877 0.18 ENSDART00000044683
ftcd
formimidoyltransferase cyclodeaminase
chr22_+_20427170 0.17 ENSDART00000136744
foxq2
forkhead box Q2
chr2_+_6963296 0.17 ENSDART00000147146
ddr2b
discoidin domain receptor tyrosine kinase 2b
chr17_-_19019635 0.17 ENSDART00000126666
flrt2
fibronectin leucine rich transmembrane protein 2
chr16_+_5774977 0.17 ENSDART00000134202
ccka
cholecystokinin a
chr1_-_36152131 0.17 ENSDART00000182113
ENSDART00000182904
znf827
zinc finger protein 827
chr10_+_29698467 0.17 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr15_+_21276735 0.17 ENSDART00000111213
ubash3bb
ubiquitin associated and SH3 domain containing Bb
chr10_+_37137464 0.17 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr1_+_52929185 0.16 ENSDART00000147683
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr8_-_25329967 0.16 ENSDART00000139682
eps8l3b
EPS8-like 3b
chr1_+_25801648 0.16 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr17_+_29276544 0.16 ENSDART00000049399
ankrd9
ankyrin repeat domain 9
chr2_+_50608099 0.16 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr10_+_32683089 0.16 ENSDART00000063551
ppm1e
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr13_+_38521152 0.16 ENSDART00000145292
adgrb3
adhesion G protein-coupled receptor B3
chr11_+_30057762 0.16 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr23_+_28731379 0.16 ENSDART00000047378
cort
cortistatin
chr22_-_24738188 0.15 ENSDART00000050238
vtg1
vitellogenin 1
chr12_+_31713239 0.15 ENSDART00000122379
habp2
hyaluronan binding protein 2
chr10_-_8060573 0.15 ENSDART00000147104
ENSDART00000099030
si:ch211-251f6.6
si:ch211-251f6.6
chr10_-_26512993 0.15 ENSDART00000188549
ENSDART00000193316
si:dkey-5g14.1
si:dkey-5g14.1
chr11_+_30000814 0.15 ENSDART00000191011
ENSDART00000189770
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr8_-_42238543 0.15 ENSDART00000062697
gfra2a
GDNF family receptor alpha 2a
chr5_-_28109416 0.15 ENSDART00000042002
si:ch211-48m9.1
si:ch211-48m9.1
chr15_+_36457888 0.15 ENSDART00000155100
si:dkey-262k9.2
si:dkey-262k9.2
chr4_+_12615836 0.15 ENSDART00000003583
lmo3
LIM domain only 3
chr1_+_33969015 0.15 ENSDART00000042984
ENSDART00000146530
epha6
eph receptor A6
chr6_-_10320676 0.15 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr15_-_6247775 0.14 ENSDART00000148350
dscamb
Down syndrome cell adhesion molecule b
chr1_+_12766351 0.14 ENSDART00000165785
pcdh10a
protocadherin 10a
chr14_+_45406299 0.14 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr23_+_21638258 0.14 ENSDART00000104188
igsf21b
immunoglobin superfamily, member 21b
chr18_-_48550426 0.14 ENSDART00000145189
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr21_+_28445052 0.14 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr12_-_19007834 0.14 ENSDART00000153248
chadlb
chondroadherin-like b
chr22_-_24791505 0.14 ENSDART00000136837
vtg4
vitellogenin 4
chr18_-_1185772 0.14 ENSDART00000143245
nptnb
neuroplastin b
chr20_+_4060839 0.14 ENSDART00000178565
TRIM67
tripartite motif containing 67
chr18_+_15644559 0.14 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr14_+_14662116 0.14 ENSDART00000161693
cetn2
centrin, EF-hand protein, 2
chr16_+_13818500 0.14 ENSDART00000135245
flcn
folliculin
chr14_-_17622080 0.14 ENSDART00000112149
si:ch211-159i8.4
si:ch211-159i8.4
chr20_-_9436521 0.14 ENSDART00000133000
zgc:101840
zgc:101840
chr7_+_25059845 0.14 ENSDART00000077215
ppp2r5b
protein phosphatase 2, regulatory subunit B', beta
chr2_+_51183320 0.14 ENSDART00000167430
lrrc24
leucine rich repeat containing 24
chr13_-_33170733 0.14 ENSDART00000057382
fbln5
fibulin 5
chr23_+_6795709 0.14 ENSDART00000149136
si:ch211-117c9.5
si:ch211-117c9.5
chr10_-_33621739 0.13 ENSDART00000142655
ENSDART00000128049
hunk
hormonally up-regulated Neu-associated kinase
chr11_+_10909183 0.13 ENSDART00000064860
rbms1a
RNA binding motif, single stranded interacting protein 1a
chr3_+_33341640 0.13 ENSDART00000186352
pyya
peptide YYa
chr10_-_17159761 0.13 ENSDART00000080449
slc5a1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr11_-_6188413 0.13 ENSDART00000109972
ccl44
chemokine (C-C motif) ligand 44
chr19_+_42470396 0.13 ENSDART00000191679
si:dkey-166k12.1
si:dkey-166k12.1
chr1_+_8601935 0.13 ENSDART00000152367
si:ch211-160d14.6
si:ch211-160d14.6
chr7_+_17229980 0.13 ENSDART00000184910
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr2_+_20332044 0.13 ENSDART00000112131
plppr4a
phospholipid phosphatase related 4a
chr7_+_25033924 0.13 ENSDART00000170873
sb:cb1058
sb:cb1058
chr10_-_8053753 0.13 ENSDART00000162289
si:ch211-251f6.7
si:ch211-251f6.7
chr17_-_37395460 0.13 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr9_+_33357011 0.13 ENSDART00000088569
nyx
nyctalopin
chr2_-_10338759 0.13 ENSDART00000150166
ENSDART00000149584
gng12a
guanine nucleotide binding protein (G protein), gamma 12a
chr9_+_31795343 0.13 ENSDART00000139584
itgbl1
integrin, beta-like 1
chr16_+_13818743 0.13 ENSDART00000090191
flcn
folliculin
chr10_-_24371312 0.13 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr13_-_31812394 0.13 ENSDART00000124445
sertad4
SERTA domain containing 4
chr19_-_31522625 0.12 ENSDART00000158438
ENSDART00000035049
necab1
N-terminal EF-hand calcium binding protein 1
chr1_-_19215336 0.12 ENSDART00000162949
ENSDART00000170680
ptprdb
protein tyrosine phosphatase, receptor type, D, b
chr19_-_205104 0.12 ENSDART00000011890
zbtb22a
zinc finger and BTB domain containing 22a
chr6_+_39098397 0.12 ENSDART00000003716
ENSDART00000188655
prss60.2
protease, serine, 60.2
chr20_-_9462433 0.12 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr11_-_37997419 0.12 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr24_+_13316737 0.12 ENSDART00000191658
SBSPON
somatomedin B and thrombospondin type 1 domain containing
chr20_-_39271844 0.12 ENSDART00000192708
clu
clusterin
chr24_+_2519761 0.12 ENSDART00000106619
nrn1a
neuritin 1a
chr1_+_12767318 0.12 ENSDART00000162652
pcdh10a
protocadherin 10a
chr3_-_34337969 0.12 ENSDART00000151634
tnrc6c1
trinucleotide repeat containing 6C1
chr6_-_41229787 0.12 ENSDART00000065013
synpr
synaptoporin
chr23_+_20563779 0.12 ENSDART00000146008
camkvl
CaM kinase-like vesicle-associated, like
chr6_-_38419318 0.12 ENSDART00000138026
gabra5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr13_-_32635859 0.12 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matn3b
matrilin 3b
chr11_-_37509001 0.12 ENSDART00000109753
bsnb
bassoon (presynaptic cytomatrix protein) b
chr21_+_13366353 0.12 ENSDART00000151630
si:ch73-62l21.1
si:ch73-62l21.1
chr15_-_23376541 0.11 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr20_-_38617766 0.11 ENSDART00000050474
slc30a2
solute carrier family 30 (zinc transporter), member 2
chr13_+_25449681 0.11 ENSDART00000101328
atoh7
atonal bHLH transcription factor 7
chr8_+_7144066 0.11 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr15_-_34213898 0.11 ENSDART00000191945
ENSDART00000186089
etv1
ets variant 1
chr21_+_28958471 0.11 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr23_-_20051369 0.11 ENSDART00000049836
bgnb
biglycan b
chr12_-_28881638 0.11 ENSDART00000148459
ENSDART00000039667
ENSDART00000148668
ENSDART00000136593
ENSDART00000139923
ENSDART00000148912
cbx1b
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr5_+_36611128 0.11 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr9_-_12424791 0.11 ENSDART00000135447
ENSDART00000088199
zgc:162707
zgc:162707
chr1_+_40023640 0.11 ENSDART00000101623
lgi2b
leucine-rich repeat LGI family, member 2b
chr3_-_23406964 0.11 ENSDART00000114723
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr20_-_14925281 0.11 ENSDART00000152641
dnm3a
dynamin 3a
chr3_-_39695856 0.11 ENSDART00000148247
b9d1
B9 protein domain 1
chr10_-_8053385 0.11 ENSDART00000142714
si:ch211-251f6.7
si:ch211-251f6.7
chr21_+_21655755 0.11 ENSDART00000079524
or125-8
odorant receptor, family E, subfamily 125, member 8
chr14_-_33821515 0.11 ENSDART00000173218
vimr2
vimentin-related 2
chr7_-_69521481 0.10 ENSDART00000148465
slc1a1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr22_-_13851297 0.10 ENSDART00000080306
s100b
S100 calcium binding protein, beta (neural)
chr10_-_8046764 0.10 ENSDART00000099031
zgc:136254
zgc:136254
chr6_-_38816500 0.10 ENSDART00000190866
ENSDART00000104124
cnga3a
cyclic nucleotide gated channel alpha 3a
chr15_-_22074315 0.10 ENSDART00000149830
drd2a
dopamine receptor D2a
chr19_-_20482261 0.10 ENSDART00000056205
satb1a
SATB homeobox 1a
chr24_+_5208171 0.10 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
si:ch73-206p6.1
chr23_-_44233408 0.10 ENSDART00000149318
ENSDART00000085528
zgc:158659
zgc:158659
chr20_-_35040041 0.10 ENSDART00000131919
kif26bb
kinesin family member 26Bb
chr4_+_11384891 0.10 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr22_+_661505 0.10 ENSDART00000149460
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr20_-_40754794 0.10 ENSDART00000187251
cx32.3
connexin 32.3
chr22_-_24818066 0.10 ENSDART00000143443
vtg6
vitellogenin 6
chr22_+_35068046 0.10 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
si:ch73-173h19.3
chr8_-_14126646 0.10 ENSDART00000027225
bgna
biglycan a
chr14_-_49133426 0.10 ENSDART00000042421
ppp2ca
protein phosphatase 2, catalytic subunit, alpha isozyme
chr17_+_43032529 0.10 ENSDART00000055611
ENSDART00000154863
isca2
iron-sulfur cluster assembly 2
chr1_+_50538839 0.10 ENSDART00000020412
pkd2
polycystic kidney disease 2
chr24_-_26399623 0.10 ENSDART00000112317
zgc:194621
zgc:194621
chr14_-_3381303 0.10 ENSDART00000171601
im:7150988
im:7150988
chr10_+_16584382 0.10 ENSDART00000112039
CR790388.1

chr23_-_26522760 0.10 ENSDART00000142417
ENSDART00000135606
ENSDART00000122668
si:dkey-205h13.1
si:dkey-205h13.1
chr16_+_34531486 0.10 ENSDART00000043291
paqr7b
progestin and adipoQ receptor family member VII, b
chr1_+_34181581 0.10 ENSDART00000146042
epha6
eph receptor A6
chr4_+_31405646 0.10 ENSDART00000128732
si:rp71-5o12.3
si:rp71-5o12.3
chr16_-_13623928 0.10 ENSDART00000164344
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr19_-_31402429 0.10 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr23_+_5977965 0.10 ENSDART00000115403
ENSDART00000183147
NAV1 (1 of many)
neuron navigator 1
chr9_+_54417141 0.10 ENSDART00000056810
drd1b
dopamine receptor D1b
chr20_+_40457599 0.10 ENSDART00000017553
serinc1
serine incorporator 1
chr1_+_52392511 0.10 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr25_-_20378721 0.10 ENSDART00000181707
kctd15a
potassium channel tetramerization domain containing 15a
chr15_-_2184638 0.10 ENSDART00000135460
shox2
short stature homeobox 2
chr22_-_15010688 0.10 ENSDART00000139892
elfn2a
extracellular leucine-rich repeat and fibronectin type III domain containing 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx6.1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0046351 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.1 0.4 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.4 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.8 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 0.2 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.2 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.0 0.1 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.2 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.3 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.1 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.0 0.3 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.3 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.1 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0043090 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.0 0.1 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0042311 vasodilation(GO:0042311)
0.0 0.0 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:1902260 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.4 GO:0032355 response to estradiol(GO:0032355)
0.0 0.1 GO:0098586 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.0 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.0 0.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0001996 regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993) positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0043679 axon terminus(GO:0043679)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.1 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.4 GO:0045735 nutrient reservoir activity(GO:0045735)
0.1 0.4 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462)
0.0 0.1 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.3 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.1 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.1 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane