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PRJNA195909:zebrafish embryo and larva development

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Results for nr1d2a

Z-value: 1.18

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Transcription factors associated with nr1d2a

Gene Symbol Gene ID Gene Info
nr1d2a
ENSDARG00000003820 nuclear receptor subfamily 1, group D, member 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr1d2adr11_v1_chr16_+_50089417_500894170.932.7e-04Click!

Activity profile of nr1d2a motif

Sorted Z-values of nr1d2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_9561066 3.13 ENSDART00000136281
si:ch211-243g18.2
si:ch211-243g18.2
chr16_+_23921610 2.33 ENSDART00000143855
apoa4b.3
apolipoprotein A-IV b, tandem duplicate 3
chr18_+_22302635 2.16 ENSDART00000141051
carmil2
capping protein regulator and myosin 1 linker 2
chr20_+_16750177 2.08 ENSDART00000185357
calm1b
calmodulin 1b
chr6_+_15268685 2.05 ENSDART00000128090
ENSDART00000154417
ecrg4b
esophageal cancer related gene 4b
chr5_+_70155935 2.03 ENSDART00000165570
rgs3a
regulator of G protein signaling 3a
chr10_+_9553935 1.92 ENSDART00000028855
si:ch211-243g18.2
si:ch211-243g18.2
chr24_-_32408404 1.87 ENSDART00000144157
si:ch211-56a11.2
si:ch211-56a11.2
chr1_-_49498116 1.81 ENSDART00000137357
zgc:175214
zgc:175214
chr21_+_40106448 1.79 ENSDART00000100166
serpinf1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_-_6738538 1.76 ENSDART00000157125
vsnl1b
visinin-like 1b
chr7_+_40228422 1.58 ENSDART00000052222
ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr25_+_6306885 1.52 ENSDART00000142705
ENSDART00000067510
crabp1a
cellular retinoic acid binding protein 1a
chr4_+_7677318 1.42 ENSDART00000149218
elk3
ELK3, ETS-domain protein
chr20_-_9980318 1.35 ENSDART00000080664
ACTC1
zgc:86709
chr12_+_13244149 1.27 ENSDART00000186984
ENSDART00000105896
atp2a1l
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr21_+_30549512 1.24 ENSDART00000132831
rab38c
RAB38c, member of RAS oncogene family
chr7_-_8577190 1.20 ENSDART00000173174
jac3
jacalin 3
chr19_+_4990320 1.08 ENSDART00000147056
zgc:91968
zgc:91968
chr20_+_34320635 1.04 ENSDART00000153207
ivns1abpa
influenza virus NS1A binding protein a
chr5_-_65021736 1.01 ENSDART00000162368
ENSDART00000161876
anxa1c
annexin A1c
chr20_+_36233873 1.00 ENSDART00000131867
cnih3
cornichon family AMPA receptor auxiliary protein 3
chr17_-_42213285 0.96 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr15_+_19682013 0.96 ENSDART00000127368
si:dkey-4p15.5
si:dkey-4p15.5
chr6_+_57541776 0.93 ENSDART00000157330
necab3
N-terminal EF-hand calcium binding protein 3
chr14_+_17376940 0.91 ENSDART00000054590
ENSDART00000010148
spon2b
spondin 2b, extracellular matrix protein
chr25_-_27843066 0.86 ENSDART00000179684
ENSDART00000186000
ENSDART00000190065
asb15a
ankyrin repeat and SOCS box containing 15a
chr6_-_39605734 0.86 ENSDART00000044276
ENSDART00000179059
dip2bb
disco-interacting protein 2 homolog Bb
chr23_-_5683147 0.85 ENSDART00000102766
ENSDART00000067351
tnnt2a
troponin T type 2a (cardiac)
chr10_-_1788376 0.79 ENSDART00000123842
epb41l4a
erythrocyte membrane protein band 4.1 like 4A
chr6_-_40312091 0.79 ENSDART00000154878
col7a1
collagen, type VII, alpha 1
chr19_+_4990496 0.72 ENSDART00000151050
ENSDART00000017535
zgc:91968
zgc:91968
chr3_-_16039619 0.71 ENSDART00000143324
spsb3a
splA/ryanodine receptor domain and SOCS box containing 3a
chr7_+_15871156 0.69 ENSDART00000145946
pax6b
paired box 6b
chr12_+_28574863 0.68 ENSDART00000153284
tbkbp1
TBK1 binding protein 1
chr9_-_48937089 0.67 ENSDART00000193442
cers6
ceramide synthase 6
chr8_+_14158021 0.66 ENSDART00000080832
si:dkey-6n6.2
si:dkey-6n6.2
chr1_+_26667872 0.65 ENSDART00000152803
ENSDART00000152144
ENSDART00000152785
ENSDART00000152393
hemgn
hemogen
chr18_-_15559817 0.65 ENSDART00000061681
si:ch211-245j22.3
si:ch211-245j22.3
chr16_+_8716800 0.65 ENSDART00000124693
ENSDART00000181961
cabz01093075.1
cabz01093075.1
chr18_-_39473055 0.65 ENSDART00000122930
scg3
secretogranin III
chr7_+_15871408 0.64 ENSDART00000014572
pax6b
paired box 6b
chr18_+_27738349 0.63 ENSDART00000187816
tspan18b
tetraspanin 18b
chr1_-_44704261 0.62 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr12_+_9542124 0.62 ENSDART00000127952
p4ha1a
prolyl 4-hydroxylase, alpha polypeptide I a
chr15_+_42599501 0.60 ENSDART00000177646
grik1b
glutamate receptor, ionotropic, kainate 1b
chr16_-_24561354 0.60 ENSDART00000193278
ENSDART00000126274
si:ch211-79k12.2
si:ch211-79k12.2
chr15_-_24178893 0.59 ENSDART00000077980
pipox
pipecolic acid oxidase
chr6_+_2030703 0.58 ENSDART00000109679
ENSDART00000187502
ENSDART00000191165
ENSDART00000187544
quo
quattro
chr8_+_43016714 0.58 ENSDART00000142671
rassf2a
Ras association (RalGDS/AF-6) domain family member 2a
chr5_-_67878064 0.58 ENSDART00000111203
tagln3a
transgelin 3a
chr8_+_43340995 0.57 ENSDART00000038566
rflna
refilin A
chr5_-_23179319 0.56 ENSDART00000161883
ENSDART00000136260
si:dkey-114c15.5
si:dkey-114c15.5
chr14_-_42997145 0.56 ENSDART00000172801
pcdh10b
protocadherin 10b
chr23_+_36144487 0.55 ENSDART00000082473
hoxc3a
homeobox C3a
chr2_+_31804582 0.55 ENSDART00000086646
rnf182
ring finger protein 182
chr7_+_66048102 0.55 ENSDART00000104523
arntl1b
aryl hydrocarbon receptor nuclear translocator-like 1b
chr3_+_35298078 0.54 ENSDART00000110126
cacng3b
calcium channel, voltage-dependent, gamma subunit 3b
chr15_+_19681718 0.53 ENSDART00000164803
si:dkey-4p15.5
si:dkey-4p15.5
chr12_-_32183164 0.51 ENSDART00000191269
ENSDART00000173549
SMIM36
si:ch73-256g18.2
chr19_+_18797623 0.51 ENSDART00000166172
ddah2
dimethylarginine dimethylaminohydrolase 2
chr3_+_1016404 0.51 ENSDART00000189545
si:ch1073-464p5.5
si:ch1073-464p5.5
chr11_+_30672282 0.50 ENSDART00000023981
ENSDART00000188846
ttbk1a
tau tubulin kinase 1a
chr2_-_56655769 0.48 ENSDART00000113589
gpx4b
glutathione peroxidase 4b
chr16_+_30438041 0.47 ENSDART00000137977
pear1
platelet endothelial aggregation receptor 1
chr16_-_8927425 0.47 ENSDART00000000382
triob
trio Rho guanine nucleotide exchange factor b
chr25_-_1235457 0.46 ENSDART00000093093
coro2bb
coronin, actin binding protein, 2Bb
chr9_-_8661436 0.46 ENSDART00000130442
col4a1
collagen, type IV, alpha 1
chr22_-_11124419 0.45 ENSDART00000149634
atp6ap2
ATPase H+ transporting accessory protein 2
chr23_+_19564392 0.44 ENSDART00000144746
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr14_-_29858883 0.43 ENSDART00000141034
sorbs2b
sorbin and SH3 domain containing 2b
chr18_-_35736591 0.43 ENSDART00000036015
ryr1b
ryanodine receptor 1b (skeletal)
chr11_-_21014572 0.41 ENSDART00000042220
slc6a14
solute carrier family 6 (amino acid transporter), member 14
chr17_-_42213822 0.40 ENSDART00000187904
ENSDART00000180029
nkx2.2a
NK2 homeobox 2a
chr25_-_27842654 0.40 ENSDART00000154852
ENSDART00000156906
asb15a
ankyrin repeat and SOCS box containing 15a
chr5_+_19261391 0.39 ENSDART00000089173
atp8b5a
ATPase phospholipid transporting 8B5a
chr3_+_32698424 0.39 ENSDART00000055340
fus
FUS RNA binding protein
chr12_+_7399403 0.39 ENSDART00000103526
bicc1b
BicC family RNA binding protein 1b
chr22_+_13917311 0.38 ENSDART00000022654
sh3bp4a
SH3-domain binding protein 4a
chr6_+_32415132 0.38 ENSDART00000155790
kank4
KN motif and ankyrin repeat domains 4
chr2_+_20410652 0.37 ENSDART00000185940
palmda
palmdelphin a
chr6_-_49159207 0.36 ENSDART00000041942
tspan2a
tetraspanin 2a
chr2_-_8648440 0.36 ENSDART00000135743
si:ch211-71m22.3
si:ch211-71m22.3
chr25_+_14165447 0.34 ENSDART00000145387
shank2
SH3 and multiple ankyrin repeat domains 2
chr1_-_30039331 0.34 ENSDART00000086935
ENSDART00000143800
MARCH4 (1 of many)
zgc:153256
chr2_+_30721070 0.34 ENSDART00000099052
si:dkey-94e7.2
si:dkey-94e7.2
chr8_+_21146262 0.34 ENSDART00000045684
porcn
porcupine O-acyltransferase
chr12_-_32013125 0.34 ENSDART00000153355
grin2cb
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
chr25_+_31264155 0.34 ENSDART00000012256
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr1_+_19930520 0.33 ENSDART00000158344
apbb2b
amyloid beta (A4) precursor protein-binding, family B, member 2b
chr13_+_29470442 0.33 ENSDART00000028417
lrit2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr5_+_19261687 0.33 ENSDART00000139401
atp8b5a
ATPase phospholipid transporting 8B5a
chr14_-_29859067 0.33 ENSDART00000136380
sorbs2b
sorbin and SH3 domain containing 2b
chr2_-_16380283 0.32 ENSDART00000149992
si:dkey-231j24.3
si:dkey-231j24.3
chr4_+_7876197 0.32 ENSDART00000111986
ENSDART00000189601
cdc123
cell division cycle 123 homolog (S. cerevisiae)
chr2_+_20430366 0.31 ENSDART00000155108
si:ch211-153l6.6
si:ch211-153l6.6
chr12_-_3756405 0.31 ENSDART00000150839
fam57bb
family with sequence similarity 57, member Bb
chr10_-_7988396 0.30 ENSDART00000141445
ENSDART00000024282
ewsr1a
EWS RNA-binding protein 1a
chr14_-_22390821 0.30 ENSDART00000054396
fbxl3l
F-box and leucine-rich repeat protein 3, like
chr23_-_44233408 0.29 ENSDART00000149318
ENSDART00000085528
zgc:158659
zgc:158659
chr9_+_35876927 0.27 ENSDART00000138834
mab21l3
mab-21-like 3
chr16_+_11558868 0.27 ENSDART00000112497
ENSDART00000180445
zgc:198329
zgc:198329
chr11_-_21304452 0.26 ENSDART00000163008
RASSF5
si:dkey-85p17.3
chr8_-_3773374 0.26 ENSDART00000115036
bicdl1
BICD family like cargo adaptor 1
chr22_+_21317597 0.26 ENSDART00000132605
shc2
SHC (Src homology 2 domain containing) transforming protein 2
chr22_-_23000815 0.25 ENSDART00000137111
ptprc
protein tyrosine phosphatase, receptor type, C
chr23_+_44614056 0.24 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr17_-_23416897 0.23 ENSDART00000163391
si:ch211-149k12.3
si:ch211-149k12.3
chr24_-_23716097 0.23 ENSDART00000084954
ENSDART00000129028
pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr20_-_14680897 0.23 ENSDART00000063857
ENSDART00000161314
scrn2
secernin 2
chr1_-_21297748 0.20 ENSDART00000142109
npy1r
neuropeptide Y receptor Y1
chr15_+_5360407 0.20 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr6_-_31364475 0.18 ENSDART00000145715
ENSDART00000134370
ak4
adenylate kinase 4
chr11_+_19159083 0.18 ENSDART00000138964
adamts9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr13_+_30172645 0.18 ENSDART00000137114
pald1b
phosphatase domain containing, paladin 1b
chr8_+_18463797 0.17 ENSDART00000148958
alkal1
ALK and LTK ligand 1
chr5_-_30079434 0.17 ENSDART00000133981
bco2a
beta-carotene oxygenase 2a
chr18_+_7594012 0.17 ENSDART00000062150
zgc:77752
zgc:77752
chr3_-_2591942 0.16 ENSDART00000127971
si:dkey-217f16.5
si:dkey-217f16.5
chr1_+_15204633 0.16 ENSDART00000188410
itln1
intelectin 1
chr3_+_57997980 0.15 ENSDART00000168477
ENSDART00000193840
pycr1a
pyrroline-5-carboxylate reductase 1a
chr1_-_31140096 0.14 ENSDART00000172243
kcnq5b
potassium voltage-gated channel, KQT-like subfamily, member 5b
chr5_-_35888499 0.14 ENSDART00000193932
rxfp2l
relaxin/insulin-like family peptide receptor 2, like
chr3_-_29508959 0.12 ENSDART00000055408
cyth4a
cytohesin 4a
chr1_-_33353778 0.12 ENSDART00000041191
gyg2
glycogenin 2
chr1_+_55752593 0.12 ENSDART00000108838
ENSDART00000134770
tecrb
trans-2,3-enoyl-CoA reductase b
chr22_+_786556 0.12 ENSDART00000125347
cry1bb
cryptochrome circadian clock 1bb
chr15_-_31419805 0.12 ENSDART00000060111
or111-11
odorant receptor, family D, subfamily 111, member 11
chr16_+_12632428 0.11 ENSDART00000184600
ENSDART00000180537
nat14
N-acetyltransferase 14 (GCN5-related, putative)
chr19_+_2590182 0.10 ENSDART00000162293
si:ch73-345f18.3
si:ch73-345f18.3
chr12_+_19305390 0.10 ENSDART00000183987
ENSDART00000066391
csnk1e
casein kinase 1, epsilon
chr14_-_24001825 0.09 ENSDART00000130704
il4
interleukin 4
chr3_-_2592350 0.08 ENSDART00000192325
si:dkey-217f16.5
si:dkey-217f16.5
chr18_+_907266 0.08 ENSDART00000171729
pkma
pyruvate kinase M1/2a
chr15_+_17030941 0.07 ENSDART00000062069
plin2
perilipin 2
chr8_+_18464235 0.06 ENSDART00000110571
alkal1
ALK and LTK ligand 1
chr3_-_16289826 0.05 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr1_+_9708801 0.05 ENSDART00000189621
elfn1b
extracellular leucine-rich repeat and fibronectin type III domain containing 1b
chr19_-_15335787 0.05 ENSDART00000187131
hivep3a
human immunodeficiency virus type I enhancer binding protein 3a
chr22_-_4913031 0.05 ENSDART00000132062
si:ch73-256j6.3
si:ch73-256j6.3
chr15_+_2559875 0.05 ENSDART00000178505
SH2B2
SH2B adaptor protein 2
chr13_+_25486608 0.04 ENSDART00000057689
bag3
BCL2 associated athanogene 3
chr20_+_46202188 0.03 ENSDART00000100523
taar13c
trace amine associated receptor 13c
chr8_+_21225064 0.02 ENSDART00000129210
cry1ba
cryptochrome circadian clock 1ba
chr11_-_21303946 0.02 ENSDART00000185786
RASSF5
si:dkey-85p17.3
chr12_+_23912074 0.01 ENSDART00000152864
svila
supervillin a
chr21_+_27189490 0.00 ENSDART00000125349
bada
BCL2 associated agonist of cell death a

Network of associatons between targets according to the STRING database.

First level regulatory network of nr1d2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0070314 G1 to G0 transition(GO:0070314)
0.5 1.4 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.4 2.0 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.3 1.5 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.2 0.9 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.2 0.8 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.2 1.3 GO:0090104 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.2 1.0 GO:0046638 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.6 GO:0019477 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 2.2 GO:0030011 maintenance of cell polarity(GO:0030011)
0.1 0.9 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.5 GO:0045429 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.1 0.3 GO:0061355 Wnt protein secretion(GO:0061355)
0.1 1.6 GO:0090382 phagosome maturation(GO:0090382)
0.1 0.4 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.4 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.1 0.3 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 0.6 GO:0021794 thalamus development(GO:0021794)
0.1 1.1 GO:0032438 melanosome organization(GO:0032438)
0.0 0.2 GO:0070378 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 1.9 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 1.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.6 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.3 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.2 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.0 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.7 GO:0046513 ceramide biosynthetic process(GO:0046513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 2.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.4 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 1.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 4.4 GO:0005882 intermediate filament(GO:0005882)
0.0 1.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.6 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.5 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.6 GO:0031005 filamin binding(GO:0031005)
0.1 1.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.6 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.5 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.4 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.8 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.2 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 2.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 2.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis