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PRJNA195909:zebrafish embryo and larva development

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Results for nr2c2

Z-value: 0.90

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Transcription factors associated with nr2c2

Gene Symbol Gene ID Gene Info
nr2c2
ENSDARG00000042477 nuclear receptor subfamily 2, group C, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2c2dr11_v1_chr8_+_53120278_531202780.235.5e-01Click!

Activity profile of nr2c2 motif

Sorted Z-values of nr2c2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_44027391 1.31 ENSDART00000145404
crybb1
crystallin, beta B1
chr5_-_36837846 1.12 ENSDART00000032481
ckma
creatine kinase, muscle a
chr2_-_7666021 1.09 ENSDART00000180007
CABZ01021592.1

chr6_-_13783604 1.08 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
cryba2a
crystallin, beta A2a
chr11_+_30729745 0.95 ENSDART00000103270
slc22a7a
solute carrier family 22 (organic anion transporter), member 7a
chr2_+_42191592 0.95 ENSDART00000144716
cavin4a
caveolae associated protein 4a
chr3_-_31804481 0.94 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr12_-_5120339 0.93 ENSDART00000168759
rbp4
retinol binding protein 4, plasma
chr21_-_19006631 0.93 ENSDART00000080269
ENSDART00000191682
pgam2
phosphoglycerate mutase 2 (muscle)
chr12_-_5120175 0.90 ENSDART00000160729
rbp4
retinol binding protein 4, plasma
chr9_+_32978302 0.90 ENSDART00000007630
nhlh2
nescient helix loop helix 2
chr22_-_23668356 0.85 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
cfh
complement factor H
chr13_-_39159810 0.84 ENSDART00000131508
col9a1b
collagen, type IX, alpha 1b
chr25_-_204019 0.80 ENSDART00000188440
ENSDART00000191735
FP236318.2

chr13_-_39160018 0.76 ENSDART00000168795
col9a1b
collagen, type IX, alpha 1b
chr6_+_60055168 0.71 ENSDART00000008752
pck1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr12_-_4683325 0.69 ENSDART00000152771
si:ch211-255p10.3
si:ch211-255p10.3
chr21_-_41870029 0.69 ENSDART00000182035
endou2
endonuclease, polyU-specific 2
chr20_+_15015557 0.67 ENSDART00000039345
myoc
myocilin
chr10_+_35417099 0.64 ENSDART00000063398
hhla2a.1
HERV-H LTR-associating 2a, tandem duplicate 1
chr10_+_43994471 0.62 ENSDART00000138242
ENSDART00000186359
cldn5b
claudin 5b
chr4_+_12031958 0.61 ENSDART00000044154
tnnt2c
troponin T2c, cardiac
chr10_-_29900546 0.61 ENSDART00000147441
lim2.1
lens intrinsic membrane protein 2.1
chr21_-_35832548 0.56 ENSDART00000180840
sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr25_+_15647993 0.56 ENSDART00000186578
ENSDART00000031828
spon1b
spondin 1b
chr5_+_36974931 0.55 ENSDART00000193063
gjd1a
gap junction protein delta 1a
chr22_+_38229321 0.54 ENSDART00000132670
ENSDART00000104504
si:ch211-284e20.8
si:ch211-284e20.8
chr11_+_11201096 0.52 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr3_-_12187245 0.51 ENSDART00000189553
ENSDART00000165131
srl
sarcalumenin
chr2_-_39017838 0.50 ENSDART00000048838
rbp2b
retinol binding protein 2b, cellular
chr9_+_21151138 0.50 ENSDART00000133903
hao2
hydroxyacid oxidase 2 (long chain)
chr5_+_38276582 0.49 ENSDART00000158532
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr25_+_418932 0.49 ENSDART00000059193
prtgb
protogenin homolog b (Gallus gallus)
chr10_-_22797959 0.49 ENSDART00000183269
pcolcea
procollagen C-endopeptidase enhancer a
chr9_-_22834860 0.47 ENSDART00000146486
neb
nebulin
chr10_-_29272707 0.47 ENSDART00000022605
ENSDART00000184594
ENSDART00000185371
tmem126a
transmembrane protein 126A
chr22_-_17595310 0.46 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr7_+_31871830 0.46 ENSDART00000139899
mybpc3
myosin binding protein C, cardiac
chr22_-_15587360 0.46 ENSDART00000142717
ENSDART00000138978
tpm4a
tropomyosin 4a
chr3_-_25119839 0.45 ENSDART00000154724
chadla
chondroadherin-like a
chr21_+_41743493 0.44 ENSDART00000192669
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr23_+_44634187 0.43 ENSDART00000143688
si:ch73-265d7.2
si:ch73-265d7.2
chr6_-_40429411 0.43 ENSDART00000156005
ENSDART00000156357
si:dkey-28n18.9
si:dkey-28n18.9
chr8_+_31872992 0.41 ENSDART00000146933
c7a
complement component 7a
chr23_-_15216654 0.40 ENSDART00000131649
sulf2b
sulfatase 2b
chr15_+_19797918 0.40 ENSDART00000113314
si:ch211-229d2.5
si:ch211-229d2.5
chr19_+_10979983 0.40 ENSDART00000142975
si:ch1073-70f20.1
si:ch1073-70f20.1
chr7_+_31838320 0.40 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
mybpc3
myosin binding protein C, cardiac
chr25_+_20119466 0.39 ENSDART00000104304
bpgm
2,3-bisphosphoglycerate mutase
chr19_+_40861853 0.39 ENSDART00000126470
zgc:85777
zgc:85777
chr18_-_49283058 0.39 ENSDART00000076554
si:zfos-464b6.2
si:zfos-464b6.2
chr18_+_31410652 0.39 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr8_+_999421 0.37 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr11_-_6974022 0.36 ENSDART00000172851
COMP
si:ch211-43f4.1
chr9_+_54644626 0.36 ENSDART00000190609
egfl6
EGF-like-domain, multiple 6
chr20_-_21994901 0.36 ENSDART00000004984
daam1b
dishevelled associated activator of morphogenesis 1b
chr19_-_5103141 0.36 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr21_-_44512893 0.36 ENSDART00000166853
zgc:136410
zgc:136410
chr24_-_33703504 0.35 ENSDART00000079292
cavin4b
caveolae associated protein 4b
chr19_-_5103313 0.35 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr3_-_18410968 0.34 ENSDART00000041842
ndufb10
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10
chr18_-_48517040 0.34 ENSDART00000143645
kcnj1a.3
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr18_+_17611627 0.33 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr2_-_55853943 0.33 ENSDART00000122576
rx2
retinal homeobox gene 2
chr23_+_8797143 0.33 ENSDART00000132992
sox18
SRY (sex determining region Y)-box 18
chr3_-_18792492 0.32 ENSDART00000134208
ENSDART00000034373
hagh
hydroxyacylglutathione hydrolase
chr16_-_24612871 0.32 ENSDART00000155614
ENSDART00000154787
ENSDART00000155983
ENSDART00000156519
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr23_-_45504991 0.31 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr9_-_1939232 0.31 ENSDART00000146131
hoxd3a
homeobox D3a
chr11_+_77526 0.30 ENSDART00000193521
CABZ01072242.1

chr2_-_55861351 0.30 ENSDART00000059003
rx2
retinal homeobox gene 2
chr3_-_3496738 0.30 ENSDART00000186849
CABZ01040998.1

chr10_+_20128267 0.30 ENSDART00000064615
dmtn
dematin actin binding protein
chr7_+_31319876 0.30 ENSDART00000187611
fam189a1
family with sequence similarity 189, member A1
chr25_+_18711804 0.29 ENSDART00000011149
fam185a
family with sequence similarity 185, member A
chr18_-_1185772 0.28 ENSDART00000143245
nptnb
neuroplastin b
chr15_-_6946286 0.28 ENSDART00000019330
ech1
enoyl CoA hydratase 1, peroxisomal
chr18_-_48492951 0.28 ENSDART00000146346
kcnj1a.6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr15_-_108414 0.28 ENSDART00000170044
apoa1b
apolipoprotein A-Ib
chr16_-_39131666 0.27 ENSDART00000075517
gdf6a
growth differentiation factor 6a
chr18_-_48508585 0.27 ENSDART00000133364
kcnj1a.4
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr10_+_15340768 0.27 ENSDART00000046274
ENSDART00000168909
trappc13
trafficking protein particle complex 13
chr13_-_42724645 0.27 ENSDART00000046066
capn1a
calpain 1, (mu/I) large subunit a
chr22_+_9806867 0.26 ENSDART00000137182
ENSDART00000106103
si:ch211-236g6.1
si:ch211-236g6.1
chr12_-_35787801 0.26 ENSDART00000171682
aatkb
apoptosis-associated tyrosine kinase b
chr6_+_1787160 0.26 ENSDART00000113505
myl9b
myosin, light chain 9b, regulatory
chr7_-_56180680 0.26 ENSDART00000098438
spg7
spastic paraplegia 7
chr24_-_21674950 0.26 ENSDART00000123216
ENSDART00000046211
lnx2a
ligand of numb-protein X 2a
chr23_+_42810055 0.25 ENSDART00000186647
myl9a
myosin, light chain 9a, regulatory
chr20_-_42702832 0.25 ENSDART00000134689
ENSDART00000045816
plg
plasminogen
chr4_-_75158035 0.24 ENSDART00000174353
CABZ01066312.1

chr7_-_38633867 0.24 ENSDART00000137424
c1qtnf4
C1q and TNF related 4
chr6_-_14004772 0.24 ENSDART00000185629
zgc:92027
zgc:92027
chr11_+_24957858 0.24 ENSDART00000145647
sulf2a
sulfatase 2a
chr6_-_11523987 0.24 ENSDART00000189363
gulp1b
GULP, engulfment adaptor PTB domain containing 1b
chr10_+_31244619 0.24 ENSDART00000145562
ENSDART00000184412
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr20_+_1996202 0.24 ENSDART00000184143
CABZ01092781.1

chr21_+_8198652 0.23 ENSDART00000011096
nr6a1b
nuclear receptor subfamily 6, group A, member 1b
chr11_-_27778831 0.23 ENSDART00000023823
cass4
Cas scaffolding protein family member 4
chr17_+_1514711 0.23 ENSDART00000165641
akt1
v-akt murine thymoma viral oncogene homolog 1
chr15_-_29598679 0.23 ENSDART00000155153
si:ch211-207n23.2
si:ch211-207n23.2
chr7_-_36113098 0.23 ENSDART00000064913
fto
fat mass and obesity associated
chr17_+_15788100 0.23 ENSDART00000027667
rragd
ras-related GTP binding D
chr5_-_23362602 0.23 ENSDART00000137120
gria3a
glutamate receptor, ionotropic, AMPA 3a
chr23_-_637347 0.23 ENSDART00000132175
l1camb
L1 cell adhesion molecule, paralog b
chr13_+_28819768 0.23 ENSDART00000191401
ENSDART00000188895
ENSDART00000101653
CU639469.1

chr3_+_301479 0.23 ENSDART00000165169
CABZ01075611.1

chr10_+_21650828 0.22 ENSDART00000160754
pcdh1g1
protocadherin 1 gamma 1
chr17_+_15213496 0.22 ENSDART00000058351
ENSDART00000131663
gnpnat1
glucosamine-phosphate N-acetyltransferase 1
chr13_-_8692432 0.22 ENSDART00000058106
mcfd2
multiple coagulation factor deficiency 2
chr23_+_27912079 0.22 ENSDART00000171859
BX539336.1

chr16_+_7985886 0.22 ENSDART00000126041
ano10a
anoctamin 10a
chr23_+_216012 0.22 ENSDART00000181115
ENSDART00000004678
ENSDART00000190439
ENSDART00000189322
PDZD4
si:ch73-162j3.4
chr5_-_23317477 0.21 ENSDART00000090171
nlgn3b
neuroligin 3b
chr13_+_713941 0.21 ENSDART00000109737
cox15
cytochrome c oxidase assembly homolog 15 (yeast)
chr20_+_15164482 0.21 ENSDART00000181842
ENSDART00000063877
prdx6
peroxiredoxin 6
chr22_-_16997475 0.21 ENSDART00000090237
nfia
nuclear factor I/A
chr10_-_309894 0.21 ENSDART00000163287
CABZ01049607.1

chr9_-_9980704 0.21 ENSDART00000130243
ENSDART00000193475
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr11_+_25101220 0.21 ENSDART00000183700
ndrg3a
ndrg family member 3a
chr13_-_8692860 0.20 ENSDART00000058107
mcfd2
multiple coagulation factor deficiency 2
chr16_-_38518270 0.20 ENSDART00000131899
rspo2
R-spondin 2
chr6_+_39930825 0.20 ENSDART00000182352
ENSDART00000186643
ENSDART00000190513
ENSDART00000065092
ENSDART00000188645
itpr1a
inositol 1,4,5-trisphosphate receptor, type 1a
chr3_+_27770110 0.20 ENSDART00000017962
eci1
enoyl-CoA delta isomerase 1
chr7_-_24046999 0.20 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr21_+_7605803 0.19 ENSDART00000121813
wdr41
WD repeat domain 41
chr6_-_40722200 0.19 ENSDART00000035101
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr22_-_16997887 0.19 ENSDART00000138233
nfia
nuclear factor I/A
chr3_+_32553714 0.19 ENSDART00000165638
pax10
paired box 10
chr10_-_322769 0.19 ENSDART00000165244
akt2l
v-akt murine thymoma viral oncogene homolog 2, like
chr19_-_24136233 0.18 ENSDART00000143365
thap7
THAP domain containing 7
chr12_-_33568174 0.18 ENSDART00000142329
tdrkh
tudor and KH domain containing
chr23_+_2740741 0.18 ENSDART00000134938
zgc:114123
zgc:114123
chr1_-_59240975 0.18 ENSDART00000166170
mvb12a
multivesicular body subunit 12A
chr2_+_57801960 0.18 ENSDART00000147966
si:dkeyp-68b7.10
si:dkeyp-68b7.10
chr1_-_54063520 0.18 ENSDART00000171722
smdt1b
single-pass membrane protein with aspartate-rich tail 1b
chr24_-_21913426 0.18 ENSDART00000081178
c1qtnf9
C1q and TNF related 9
chr19_+_177455 0.18 ENSDART00000111580
tmem65
transmembrane protein 65
chr6_-_40722480 0.18 ENSDART00000188187
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr17_+_53425037 0.17 ENSDART00000154983
fabp10b
fatty acid binding protein 10b, liver basic
chr7_+_24115082 0.17 ENSDART00000182718
mrpl52
mitochondrial ribosomal protein L52
chr8_+_22582146 0.17 ENSDART00000157655
ENSDART00000189892
CT583651.2

chr9_+_35077546 0.17 ENSDART00000142688
si:dkey-192g7.3
si:dkey-192g7.3
chr6_-_39270851 0.17 ENSDART00000148839
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr16_-_1503023 0.17 ENSDART00000036348
sim1a
single-minded family bHLH transcription factor 1a
chr24_-_11446156 0.17 ENSDART00000143921
ENSDART00000066778
acad11
acyl-CoA dehydrogenase family, member 11
chr11_-_42472941 0.17 ENSDART00000166624
arf4b
ADP-ribosylation factor 4b
chr9_-_18742704 0.17 ENSDART00000145401
tsc22d1
TSC22 domain family, member 1
chr3_-_5829501 0.17 ENSDART00000091017
pkn1b
protein kinase N1b
chr10_-_38456382 0.17 ENSDART00000182129
gdpd5a
glycerophosphodiester phosphodiesterase domain containing 5a
chr20_+_47953047 0.17 ENSDART00000079734
hadhaa
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a
chr12_+_48972915 0.17 ENSDART00000170695
lrit1b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1b
chr5_+_22579975 0.16 ENSDART00000080877
tnfsf10l4
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr3_-_34180364 0.16 ENSDART00000151819
ENSDART00000003133
yipf2
Yip1 domain family, member 2
chr3_+_34180835 0.16 ENSDART00000055252
timm29
translocase of inner mitochondrial membrane 29
chr18_-_7400075 0.16 ENSDART00000101250
si:dkey-30c15.13
si:dkey-30c15.13
chr25_+_28893615 0.16 ENSDART00000156994
ENSDART00000075151
amn1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr20_-_49650293 0.16 ENSDART00000151239
col12a1b
collagen, type XII, alpha 1b
chr22_-_16997246 0.16 ENSDART00000090242
nfia
nuclear factor I/A
chr11_+_11974708 0.16 ENSDART00000125060
zgc:64002
zgc:64002
chr7_+_59649746 0.16 ENSDART00000181067
rpl34
ribosomal protein L34
chr20_-_32270866 0.15 ENSDART00000153140
armc2
armadillo repeat containing 2
chr8_-_25329967 0.15 ENSDART00000139682
eps8l3b
EPS8-like 3b
chr23_-_28808480 0.15 ENSDART00000078167
dffa
DNA fragmentation factor, alpha polypeptide
chr20_+_54738210 0.15 ENSDART00000151399
pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr4_-_858434 0.15 ENSDART00000006961
sobpb
sine oculis binding protein homolog (Drosophila) b
chr23_-_45705525 0.15 ENSDART00000148959
ednrab
endothelin receptor type Ab
chr8_+_4745340 0.15 ENSDART00000182894
ufd1l
ubiquitin recognition factor in ER associated degradation 1
chr1_-_45888608 0.15 ENSDART00000139219
pnpla6
patatin-like phospholipase domain containing 6
chr10_-_105100 0.15 ENSDART00000145716
ttc3
tetratricopeptide repeat domain 3
chr19_-_24484758 0.15 ENSDART00000052422
mtx1b
metaxin 1b
chr12_-_48992527 0.15 ENSDART00000169696
CDHR1 (1 of many)
cadherin related family member 1
chr23_+_19790962 0.14 ENSDART00000142228
flna
filamin A, alpha (actin binding protein 280)
chr8_+_15251448 0.14 ENSDART00000063717
zgc:171480
zgc:171480
chr20_+_43379029 0.14 ENSDART00000142486
ENSDART00000186486
unc93a
unc-93 homolog A
chr16_-_24605969 0.14 ENSDART00000163305
ENSDART00000167121
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr2_-_3614005 0.14 ENSDART00000110399
pter
phosphotriesterase related
chr1_-_53750522 0.14 ENSDART00000190755
akt3b
v-akt murine thymoma viral oncogene homolog 3b
chr1_+_44582369 0.14 ENSDART00000003022
ENSDART00000137980
med19b
mediator complex subunit 19b
chr2_-_42558549 0.14 ENSDART00000025997
dip2cb
disco-interacting protein 2 homolog Cb
chr10_+_26834985 0.14 ENSDART00000147518
fam89b
family with sequence similarity 89, member B
chr4_+_9400012 0.14 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr23_-_42810664 0.14 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr20_+_2281933 0.14 ENSDART00000137579
si:ch73-18b11.2
si:ch73-18b11.2
chr21_-_22317920 0.14 ENSDART00000191083
ENSDART00000108701
gdpd4b
glycerophosphodiester phosphodiesterase domain containing 4b
chr2_-_22660232 0.14 ENSDART00000174742
thap4
THAP domain containing 4
chr21_-_5856050 0.14 ENSDART00000115367
CABZ01071020.1

chr25_+_22017182 0.14 ENSDART00000156517
si:dkey-217l24.1
si:dkey-217l24.1
chr20_-_47953524 0.14 ENSDART00000167986
HADHB
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr19_+_2275019 0.13 ENSDART00000136138
itgb8
integrin, beta 8
chr23_-_46126444 0.13 ENSDART00000030004
CABZ01071903.1

chr20_+_7243879 0.13 ENSDART00000122298
bsnd
barttin CLCNK-type chloride channel accessory beta subunit
chr24_+_81527 0.13 ENSDART00000192139
reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr25_+_31929325 0.13 ENSDART00000181095
apba2a
amyloid beta (A4) precursor protein-binding, family A, member 2a
chr3_-_32590164 0.13 ENSDART00000151151
tspan4b
tetraspanin 4b
chr14_+_30413758 0.13 ENSDART00000092953
cnot7
CCR4-NOT transcription complex, subunit 7
chr22_-_3595439 0.13 ENSDART00000083308
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr16_-_21047872 0.13 ENSDART00000131582
cbx3b
chromobox homolog 3b
chr11_+_6116503 0.13 ENSDART00000176170
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr18_-_15771551 0.13 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
si:ch211-219a15.3

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2c2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0034633 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.2 0.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 0.7 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.2 0.9 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.6 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) reverse cholesterol transport(GO:0043691)
0.1 0.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.2 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.5 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.1 1.0 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.3 GO:0046551 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 0.2 GO:0033335 anal fin development(GO:0033335)
0.1 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.4 GO:0033292 T-tubule organization(GO:0033292)
0.1 0.6 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.2 GO:0072020 proximal straight tubule development(GO:0072020)
0.1 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.7 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.0 0.6 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.9 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.0 0.1 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.0 0.1 GO:0032369 negative regulation of lipid transport(GO:0032369) negative regulation of lipid catabolic process(GO:0050995)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.3 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.2 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0006921 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.3 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.6 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.7 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.1 GO:0050975 sensory perception of touch(GO:0050975)
0.0 1.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.3 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 1.2 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.7 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.3 1.8 GO:0034632 retinol transporter activity(GO:0034632)
0.2 0.7 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.7 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.0 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 1.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.2 GO:1990931 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.1 0.6 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.3 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.0 0.1 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0008126 acetylesterase activity(GO:0008126)
0.0 0.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones