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PRJNA195909:zebrafish embryo and larva development

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Results for nr4a3

Z-value: 1.15

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Transcription factors associated with nr4a3

Gene Symbol Gene ID Gene Info
nr4a3
ENSDARG00000055854 nuclear receptor subfamily 4, group A, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr4a3dr11_v1_chr16_+_27345383_27345383-0.781.3e-02Click!

Activity profile of nr4a3 motif

Sorted Z-values of nr4a3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_40708537 2.16 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr4_-_77116266 1.82 ENSDART00000174249
CU467646.2

chr4_-_77135076 1.75 ENSDART00000174184
zgc:173770
zgc:173770
chr4_-_77130289 1.74 ENSDART00000174380
CU467646.7

chr4_-_77135340 1.73 ENSDART00000180581
ENSDART00000179901
CU467646.7

chr8_-_52909850 1.66 ENSDART00000161943
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr3_-_3448095 1.55 ENSDART00000078886
A2ML1 (1 of many)
si:dkey-46g23.5
chr5_-_14509137 1.53 ENSDART00000180742
si:ch211-244o22.2
si:ch211-244o22.2
chr4_-_77120928 1.47 ENSDART00000174154
CU467646.1

chr10_-_26202766 1.47 ENSDART00000136393
fhdc3
FH2 domain containing 3
chr3_+_3454610 1.42 ENSDART00000024900
zgc:165453
zgc:165453
chr23_+_25172682 1.37 ENSDART00000191197
ENSDART00000183497
si:dkey-151g10.3
si:dkey-151g10.3
chr7_-_51775688 1.33 ENSDART00000149793
bmp15
bone morphogenetic protein 15
chr1_+_24469313 1.31 ENSDART00000176581
fam160a1a
family with sequence similarity 160, member A1a
chr19_-_35439237 1.28 ENSDART00000145883
anln
anillin, actin binding protein
chr10_+_45031398 1.27 ENSDART00000160536
gnsb
glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b
chr5_-_3839285 1.21 ENSDART00000122292
mlxipl
MLX interacting protein like
chr5_+_37406358 1.17 ENSDART00000162811
klhl13
kelch-like family member 13
chr12_+_46634736 1.15 ENSDART00000008009
trim16
tripartite motif containing 16
chr18_+_27515640 1.14 ENSDART00000181593
tp53i11b
tumor protein p53 inducible protein 11b
chr2_-_17115256 1.11 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr5_-_17876709 1.10 ENSDART00000141978
si:dkey-112e17.1
si:dkey-112e17.1
chr20_+_18260358 1.10 ENSDART00000187734
ENSDART00000191947
ENSDART00000057039
taf4b
TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr21_+_18405585 1.07 ENSDART00000139318
si:dkey-1d7.3
si:dkey-1d7.3
chr1_+_24557414 1.03 ENSDART00000076519
dctpp1
dCTP pyrophosphatase 1
chr3_-_5829501 1.01 ENSDART00000091017
pkn1b
protein kinase N1b
chr5_+_36896933 0.98 ENSDART00000151984
srsf7a
serine/arginine-rich splicing factor 7a
chr12_-_33357655 0.98 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr22_-_38274188 0.95 ENSDART00000139420
ENSDART00000015117
elavl2
ELAV like neuron-specific RNA binding protein 2
chr2_+_37897079 0.93 ENSDART00000141784
tep1
telomerase-associated protein 1
chr11_-_44999858 0.93 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr9_+_500052 0.92 ENSDART00000166707
CU984600.1

chr19_-_42045372 0.91 ENSDART00000144275
trioa
trio Rho guanine nucleotide exchange factor a
chr4_-_16451375 0.90 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr19_+_2631565 0.87 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr14_+_30413758 0.86 ENSDART00000092953
cnot7
CCR4-NOT transcription complex, subunit 7
chr10_+_36441124 0.84 ENSDART00000185626
uspl1
ubiquitin specific peptidase like 1
chr17_-_27200025 0.83 ENSDART00000192699
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr2_-_58075414 0.82 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr23_+_39346774 0.80 ENSDART00000190985
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr4_-_9191220 0.80 ENSDART00000156919
hcfc2
host cell factor C2
chr18_-_43866526 0.79 ENSDART00000111309
treh
trehalase (brush-border membrane glycoprotein)
chr23_-_27050083 0.78 ENSDART00000142324
ENSDART00000133249
ENSDART00000138751
ENSDART00000128718
zgc:66440
zgc:66440
chr3_+_7771420 0.78 ENSDART00000156809
ENSDART00000156309
hook2
hook microtubule-tethering protein 2
chr7_+_34297271 0.77 ENSDART00000180342
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr24_-_26820698 0.76 ENSDART00000147788
fndc3bb
fibronectin type III domain containing 3Bb
chr2_+_44977889 0.76 ENSDART00000144024
alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr21_+_1119046 0.75 ENSDART00000184678
CABZ01088049.1

chr16_+_52343905 0.75 ENSDART00000131051
ifnlr1
interferon lambda receptor 1
chr1_+_39859782 0.74 ENSDART00000149984
irf2a
interferon regulatory factor 2a
chr20_+_6535438 0.74 ENSDART00000145763
si:ch211-191a24.4
si:ch211-191a24.4
chr3_-_58455289 0.74 ENSDART00000052179
cdr2a
cerebellar degeneration-related protein 2a
chr23_+_24272421 0.73 ENSDART00000029974
clcnk
chloride channel K
chr17_+_654759 0.73 ENSDART00000193703
CABZ01079748.1

chr17_-_8592824 0.73 ENSDART00000127022
CU462878.1

chr8_-_22542467 0.73 ENSDART00000182588
ENSDART00000134542
csde1
cold shock domain containing E1, RNA-binding
chr1_-_39859626 0.73 ENSDART00000053763
dctd
dCMP deaminase
chr20_+_6535176 0.73 ENSDART00000054652
si:ch211-191a24.4
si:ch211-191a24.4
chr21_-_1640547 0.72 ENSDART00000151041
zgc:152948
zgc:152948
chr23_+_39346930 0.72 ENSDART00000102843
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr2_-_31700396 0.71 ENSDART00000142366
lrrcc1
leucine rich repeat and coiled-coil centrosomal protein 1
chr6_+_30533504 0.71 ENSDART00000155842
wwc3
WWC family member 3
chr1_-_58868306 0.71 ENSDART00000166615
dnm2b
dynamin 2b
chr5_-_20491198 0.70 ENSDART00000183051
ENSDART00000144232
ficd
FIC domain containing
chr22_-_7050 0.70 ENSDART00000127829
atad3
ATPase family, AAA domain containing 3
chr3_-_21166597 0.69 ENSDART00000175941
taok2a
TAO kinase 2a
chr3_-_34561624 0.67 ENSDART00000129313
sept9a
septin 9a
chr24_-_12770357 0.67 ENSDART00000060826
ipo4
importin 4
chr7_+_41887429 0.67 ENSDART00000115090
gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr24_+_39034090 0.67 ENSDART00000185763
capn15
calpain 15
chr3_-_18189283 0.67 ENSDART00000049240
tob1a
transducer of ERBB2, 1a
chr14_+_30413312 0.67 ENSDART00000186864
cnot7
CCR4-NOT transcription complex, subunit 7
chr3_+_55100045 0.66 ENSDART00000113098
hbaa1
hemoglobin, alpha adult 1
chr7_+_34296789 0.66 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr3_+_23047241 0.65 ENSDART00000103858
b4galnt2.2
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2
chr23_-_20154422 0.64 ENSDART00000132025
usp19
ubiquitin specific peptidase 19
chr18_+_44769027 0.64 ENSDART00000145190
ilvbl
ilvB (bacterial acetolactate synthase)-like
chr16_-_30655980 0.64 ENSDART00000146508
ldlrad4b
low density lipoprotein receptor class A domain containing 4b
chr3_+_35611625 0.63 ENSDART00000190995
traf7
TNF receptor-associated factor 7
chr4_-_858434 0.62 ENSDART00000006961
sobpb
sine oculis binding protein homolog (Drosophila) b
chr6_-_15065376 0.61 ENSDART00000087797
tgfbrap1
transforming growth factor, beta receptor associated protein 1
chr7_+_24520518 0.61 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr4_-_47304459 0.60 ENSDART00000169561
si:ch211-261d9.1
si:ch211-261d9.1
chr18_+_45571378 0.59 ENSDART00000077251
kifc3
kinesin family member C3
chr7_+_61764040 0.59 ENSDART00000056745
acox3
acyl-CoA oxidase 3, pristanoyl
chr15_+_40188076 0.59 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr19_+_20787179 0.58 ENSDART00000193204
adnp2b
ADNP homeobox 2b
chr20_-_44575103 0.58 ENSDART00000192573
ubxn2a
UBX domain protein 2A
chr7_+_65398161 0.57 ENSDART00000166109
ENSDART00000157399
usp47
ubiquitin specific peptidase 47
chr9_+_23770666 0.57 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3
chr22_-_24818066 0.56 ENSDART00000143443
vtg6
vitellogenin 6
chr22_-_6361178 0.55 ENSDART00000150147
zgc:113298
zgc:113298
chr13_-_25719628 0.55 ENSDART00000135383
si:dkey-192p21.6
si:dkey-192p21.6
chr25_+_28693451 0.54 ENSDART00000148366
cnot2
CCR4-NOT transcription complex, subunit 2
chr6_+_40952031 0.54 ENSDART00000189219
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr15_-_16946124 0.54 ENSDART00000154923
hip1
huntingtin interacting protein 1
chr7_-_32021853 0.54 ENSDART00000134521
kif18a
kinesin family member 18A
chr7_+_24496894 0.53 ENSDART00000149994
nelfa
negative elongation factor complex member A
chr6_-_1587291 0.53 ENSDART00000067592
ENSDART00000178877
zgc:123305
zgc:123305
chr9_-_7212973 0.53 ENSDART00000133638
mgat4a
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr18_+_21273749 0.53 ENSDART00000143265
hydin
HYDIN, axonemal central pair apparatus protein
chr5_-_13076779 0.52 ENSDART00000192826
ypel1
yippee-like 1
chr24_+_35183595 0.51 ENSDART00000075142
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr15_-_25365570 0.51 ENSDART00000152754
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr5_+_29831235 0.50 ENSDART00000109660
f11r.1
F11 receptor, tandem duplicate 1
chr2_-_4787566 0.50 ENSDART00000160663
ENSDART00000157808
tnk2b
tyrosine kinase, non-receptor, 2b
chr21_-_43398457 0.49 ENSDART00000166530
ccni2
cyclin I family, member 2
chr19_-_1947403 0.49 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
znrf2a
zinc and ring finger 2a
chr25_-_10622449 0.49 ENSDART00000155375
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr7_+_13988075 0.47 ENSDART00000186812
furina
furin (paired basic amino acid cleaving enzyme) a
chr2_+_37110504 0.47 ENSDART00000132794
ENSDART00000042974
slc1a8b
solute carrier family 1 (glutamate transporter), member 8b
chr19_-_47997424 0.46 ENSDART00000081675
ctnnb2
catenin, beta 2
chr9_+_23772516 0.46 ENSDART00000183126
si:ch211-219a4.3
si:ch211-219a4.3
chr19_+_3056450 0.46 ENSDART00000141324
ENSDART00000082353
hsf1
heat shock transcription factor 1
chr1_-_57129179 0.45 ENSDART00000157226
ENSDART00000152469
si:ch73-94k4.2
si:ch73-94k4.2
chr7_+_14005111 0.45 ENSDART00000187365
furina
furin (paired basic amino acid cleaving enzyme) a
chr6_-_35046735 0.43 ENSDART00000143649
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr2_+_50722439 0.43 ENSDART00000188927
fyco1b
FYVE and coiled-coil domain containing 1b
chr23_-_24247672 0.42 ENSDART00000141552
zbtb17
zinc finger and BTB domain containing 17
chr2_-_41562868 0.42 ENSDART00000084597
d2hgdh
D-2-hydroxyglutarate dehydrogenase
chr1_-_53625142 0.42 ENSDART00000166852
USP34
ubiquitin specific peptidase 34
chr19_-_79202 0.42 ENSDART00000166009
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr15_+_47618221 0.41 ENSDART00000168722
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component
chr14_+_20941534 0.41 ENSDART00000185616
zgc:66433
zgc:66433
chr21_-_25250594 0.40 ENSDART00000163862
nfrkb
nuclear factor related to kappaB binding protein
chr25_-_9805269 0.40 ENSDART00000192048
lrrc4c
leucine rich repeat containing 4C
chr4_-_2975461 0.40 ENSDART00000150794
plekha5
pleckstrin homology domain containing, family A member 5
chr1_+_45839927 0.39 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
map2k7
mitogen-activated protein kinase kinase 7
chr15_-_6615555 0.39 ENSDART00000152725
atm
ATM serine/threonine kinase
chr21_+_10076203 0.39 ENSDART00000190383
CABZ01043506.1

chr19_+_2877079 0.39 ENSDART00000160847
hgh1
HGH1 homolog (S. cerevisiae)
chr20_+_36806398 0.39 ENSDART00000153317
abracl
ABRA C-terminal like
chr13_-_30143127 0.38 ENSDART00000146097
tysnd1
trypsin domain containing 1
chr19_+_5146460 0.38 ENSDART00000150740
si:dkey-89b17.4
si:dkey-89b17.4
chr6_-_40044111 0.38 ENSDART00000154347
si:dkey-197j19.5
si:dkey-197j19.5
chr13_-_44842884 0.38 ENSDART00000184195
si:dkeyp-2e4.3
si:dkeyp-2e4.3
chr8_-_21110233 0.37 ENSDART00000127371
ENSDART00000100276
tmco1
transmembrane and coiled-coil domains 1
chr13_-_214122 0.37 ENSDART00000169273
ppp1r21
protein phosphatase 1, regulatory subunit 21
chr22_-_31020690 0.37 ENSDART00000130604
ssuh2.4
ssu-2 homolog, tandem duplicate 4
chr5_-_32489796 0.37 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr5_-_39698224 0.37 ENSDART00000076929
prkg2
protein kinase, cGMP-dependent, type II
chr20_+_37794633 0.36 ENSDART00000022060
atf3
activating transcription factor 3
chr2_-_56649883 0.36 ENSDART00000191786
gpx4b
glutathione peroxidase 4b
chr4_-_45337903 0.36 ENSDART00000159767
si:dkey-247i3.6
si:dkey-247i3.6
chr21_-_15200556 0.36 ENSDART00000141809
sfswap
splicing factor SWAP
chr18_-_26510545 0.34 ENSDART00000135133
FRMD5
si:ch211-69m14.1
chr25_+_35663933 0.34 ENSDART00000154979
slc2a13b
solute carrier family 2 (facilitated glucose transporter), member 13b
chr2_+_26060528 0.34 ENSDART00000058111
grin3ba
glutamate receptor, ionotropic, N-methyl-D-aspartate 3Ba
chr23_-_16737161 0.34 ENSDART00000132573
si:ch211-224l10.4
si:ch211-224l10.4
chr22_+_29113796 0.34 ENSDART00000150264
pla2g6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr8_+_8012570 0.34 ENSDART00000183429
si:ch211-169p10.1
si:ch211-169p10.1
chr16_+_25342152 0.33 ENSDART00000156351
zfat
zinc finger and AT hook domain containing
chr13_-_49666615 0.33 ENSDART00000148083
tomm20a
translocase of outer mitochondrial membrane 20
chr16_+_17252487 0.33 ENSDART00000063572
gtf3c6
general transcription factor IIIC, polypeptide 6, alpha
chr25_+_22017182 0.32 ENSDART00000156517
si:dkey-217l24.1
si:dkey-217l24.1
chr25_+_418932 0.32 ENSDART00000059193
prtgb
protogenin homolog b (Gallus gallus)
chr11_+_45287541 0.32 ENSDART00000165321
ENSDART00000173116
pycr1b
pyrroline-5-carboxylate reductase 1b
chr12_+_23866368 0.32 ENSDART00000188652
ENSDART00000192478
svila
supervillin a
chr15_+_32405959 0.31 ENSDART00000177269
si:ch211-162k9.6
si:ch211-162k9.6
chr17_-_25303486 0.31 ENSDART00000162235
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr19_+_11214007 0.31 ENSDART00000127362
si:ch73-109i22.2
si:ch73-109i22.2
chr9_-_33477588 0.31 ENSDART00000144150
caska
calcium/calmodulin-dependent serine protein kinase a
chr5_+_24156170 0.31 ENSDART00000136570
slc25a15b
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr7_+_35068036 0.31 ENSDART00000022139
zgc:136461
zgc:136461
chr9_-_44905867 0.31 ENSDART00000138316
ENSDART00000131252
ENSDART00000179383
ENSDART00000159337
zgc:66484
zgc:66484
chr13_-_3879254 0.30 ENSDART00000166427
ENSDART00000171033
si:ch211-128m15.3
si:ch211-128m15.3
chr1_+_38153944 0.30 ENSDART00000135666
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr15_+_28268135 0.30 ENSDART00000152536
ENSDART00000188550
myo1cb
myosin Ic, paralog b
chr7_+_32021982 0.30 ENSDART00000173848
mettl15
methyltransferase like 15
chr4_+_77957611 0.29 ENSDART00000156692
arfgap3
ADP-ribosylation factor GTPase activating protein 3
chr20_+_37825804 0.29 ENSDART00000152865
tatdn3
TatD DNase domain containing 3
chr23_-_27607039 0.29 ENSDART00000183639
phf8
PHD finger protein 8
chr12_-_6551681 0.28 ENSDART00000145413
si:ch211-253p2.2
si:ch211-253p2.2
chr6_+_52924103 0.28 ENSDART00000065693
or137-2
odorant receptor, family H, subfamily 137, member 2
chr4_-_4535189 0.28 ENSDART00000057519
zgc:194209
zgc:194209
chr10_+_20364009 0.28 ENSDART00000186139
ENSDART00000080395
golga7
golgin A7
chr5_-_8907819 0.28 ENSDART00000188523
adamts12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr24_-_1021318 0.28 ENSDART00000181403
ralaa
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr5_-_38197080 0.28 ENSDART00000140708
si:ch211-284e13.9
si:ch211-284e13.9
chr12_+_46791907 0.27 ENSDART00000110304
vcla
vinculin a
chr17_-_46850299 0.27 ENSDART00000154430
pimr23
Pim proto-oncogene, serine/threonine kinase, related 23
chr3_-_18373425 0.27 ENSDART00000178522
spag9a
sperm associated antigen 9a
chr3_+_31662126 0.27 ENSDART00000113441
mylk5
myosin, light chain kinase 5
chr2_-_7246848 0.27 ENSDART00000146434
zgc:153115
zgc:153115
chr1_-_55196103 0.27 ENSDART00000140153
mri1
methylthioribose-1-phosphate isomerase 1
chr16_-_11859309 0.27 ENSDART00000145754
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr22_-_6923347 0.26 ENSDART00000082048
CABZ01065328.1

chr11_-_40647190 0.25 ENSDART00000173217
ENSDART00000173276
ENSDART00000147264
fam213b
family with sequence similarity 213, member B
chr7_+_29012033 0.25 ENSDART00000173909
ENSDART00000145762
dnaaf1
dynein, axonemal, assembly factor 1
chr22_+_15720381 0.25 ENSDART00000128149
fam32a
family with sequence similarity 32, member A
chr17_-_45164291 0.25 ENSDART00000062109
noxred1
NADP-dependent oxidoreductase domain containing 1
chr19_-_17972734 0.24 ENSDART00000126298
ints8
integrator complex subunit 8
chr13_-_11578304 0.24 ENSDART00000171145
si:ch211-132e22.4
si:ch211-132e22.4
chr18_-_46295132 0.24 ENSDART00000190940
pld3
phospholipase D family, member 3
chr25_-_35095129 0.24 ENSDART00000099866
ENSDART00000099868
kif15
kinesin family member 15
chr25_-_31898552 0.24 ENSDART00000156128
si:ch73-330k17.3
si:ch73-330k17.3
chr22_-_5252005 0.23 ENSDART00000132942
ENSDART00000081801
ncln
nicalin
chr22_-_14262115 0.23 ENSDART00000168264
si:ch211-246m6.5
si:ch211-246m6.5
chr10_-_36223005 0.23 ENSDART00000159962
or109-6
odorant receptor, family D, subfamily 109, member 6
chr9_-_37613792 0.23 ENSDART00000138345
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba

Network of associatons between targets according to the STRING database.

First level regulatory network of nr4a3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.4 1.8 GO:0009219 pyrimidine deoxyribonucleotide metabolic process(GO:0009219)
0.3 1.3 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.3 1.3 GO:0008356 asymmetric cell division(GO:0008356)
0.3 0.8 GO:0005991 trehalose metabolic process(GO:0005991)
0.2 1.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.8 GO:1903405 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.2 0.7 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 0.6 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.1 0.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 1.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 1.5 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.3 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.3 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.3 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 1.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 1.4 GO:1902307 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.9 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.4 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.6 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.5 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 0.4 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.3 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.5 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.4 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.5 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.7 GO:0015671 oxygen transport(GO:0015671)
0.0 0.7 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:1903817 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.6 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.3 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.7 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 1.8 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.7 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 1.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.4 GO:2000404 regulation of T cell migration(GO:2000404)
0.0 0.5 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.5 GO:0009408 response to heat(GO:0009408)
0.0 0.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.0 0.6 GO:0032355 response to estradiol(GO:0032355)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.3 GO:0030203 glycosaminoglycan metabolic process(GO:0030203)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 1.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.6 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.0 GO:0002637 regulation of immunoglobulin production(GO:0002637) positive regulation of immunoglobulin production(GO:0002639)
0.0 0.6 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005948 acetolactate synthase complex(GO:0005948)
0.2 1.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.5 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 0.5 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 0.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.0 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.6 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.1 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0097519 DNA recombinase complex(GO:0097519)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.7 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 0.8 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.2 1.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 0.6 GO:0003984 acetolactate synthase activity(GO:0003984)
0.2 1.3 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 0.8 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2 1.0 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 0.8 GO:0032183 SUMO binding(GO:0032183)
0.1 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.6 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.6 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.4 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 1.4 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.6 GO:0045735 nutrient reservoir activity(GO:0045735)
0.1 0.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.3 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.7 GO:0031720 haptoglobin binding(GO:0031720)
0.1 1.1 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.7 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 1.0 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0005549 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.0 0.4 GO:0002020 protease binding(GO:0002020)
0.0 0.1 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.7 GO:0019239 deaminase activity(GO:0019239)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.8 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.8 GO:0030170 pyridoxal phosphate binding(GO:0030170)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 1.2 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism