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PRJNA195909:zebrafish embryo and larva development

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Results for nr5a1a+nr5a2+nr5a5

Z-value: 1.71

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Transcription factors associated with nr5a1a+nr5a2+nr5a5

Gene Symbol Gene ID Gene Info
nr5a5
ENSDARG00000039116 nuclear receptor subfamily 5, group A, member 5
nr5a2
ENSDARG00000100940 nuclear receptor subfamily 5, group A, member 2
nr5a1a
ENSDARG00000103176 nuclear receptor subfamily 5, group A, member 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr5a1adr11_v1_chr8_-_52859301_528593010.872.1e-03Click!
nr5a2dr11_v1_chr22_-_22719440_227194400.751.9e-02Click!
nr5a5dr11_v1_chr3_-_53465223_534652490.599.6e-02Click!

Activity profile of nr5a1a+nr5a2+nr5a5 motif

Sorted Z-values of nr5a1a+nr5a2+nr5a5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_1970071 4.75 ENSDART00000080608
hoxd10a
homeobox D10a
chr19_-_30404096 3.80 ENSDART00000103475
agr2
anterior gradient 2
chr15_-_23645810 3.73 ENSDART00000168845
ckmb
creatine kinase, muscle b
chr19_-_30403922 3.30 ENSDART00000181841
agr2
anterior gradient 2
chr6_-_15653494 2.50 ENSDART00000038133
trim63a
tripartite motif containing 63a
chr7_+_25913225 2.44 ENSDART00000129924
hmgb3a
high mobility group box 3a
chr20_+_10539293 2.37 ENSDART00000182265
serpina1l
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr17_-_12385308 2.24 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr22_-_2886937 2.15 ENSDART00000063533
aqp12
aquaporin 12
chr6_+_37894914 2.15 ENSDART00000148817
oca2
oculocutaneous albinism II
chr21_-_5879897 2.14 ENSDART00000184034
rpl35
ribosomal protein L35
chr20_+_218886 2.11 ENSDART00000002661
lama4
laminin, alpha 4
chr5_+_20693724 2.01 ENSDART00000141368
si:ch211-240b21.2
si:ch211-240b21.2
chr3_-_19899914 2.00 ENSDART00000134969
rnd2
Rho family GTPase 2
chr14_-_5678457 1.82 ENSDART00000012116
tlx2
T cell leukemia homeobox 2
chr7_-_26087807 1.81 ENSDART00000052989
ache
acetylcholinesterase
chr3_+_1182315 1.77 ENSDART00000055430
ndufa6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr15_-_26552393 1.75 ENSDART00000150152
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr5_-_36328688 1.74 ENSDART00000011399
efnb1
ephrin-B1
chr20_+_10545514 1.72 ENSDART00000153667
serpina1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_+_34514336 1.72 ENSDART00000024440
foxi3b
forkhead box I3b
chr14_+_6159356 1.68 ENSDART00000157730
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr17_+_7595356 1.67 ENSDART00000130625
si:dkeyp-110a12.4
si:dkeyp-110a12.4
chr10_+_25355308 1.64 ENSDART00000100415
map3k7cl
map3k7 C-terminal like
chr24_-_17029374 1.64 ENSDART00000039267
ptgdsb.1
prostaglandin D2 synthase b, tandem duplicate 1
chr7_+_30875273 1.64 ENSDART00000173693
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr16_-_42013858 1.63 ENSDART00000045403
etv2
ets variant 2
chr7_-_38658411 1.57 ENSDART00000109463
ENSDART00000017155
npsn
nephrosin
chr1_-_44940830 1.52 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
tmem176
transmembrane protein 176
chr8_-_52715911 1.52 ENSDART00000168241
tubb2b
tubulin, beta 2b
chr5_+_51594209 1.51 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr4_-_16345227 1.51 ENSDART00000079521
kera
keratocan
chr12_-_3940768 1.50 ENSDART00000134292
zgc:92040
zgc:92040
chr10_+_37927100 1.50 ENSDART00000172548
bhlha9
basic helix-loop-helix family, member a9
chr19_-_9712530 1.49 ENSDART00000134816
slc2a3a
solute carrier family 2 (facilitated glucose transporter), member 3a
chr21_-_28901095 1.49 ENSDART00000180820
cxxc5a
CXXC finger protein 5a
chr5_+_56268436 1.47 ENSDART00000021159
lhx1b
LIM homeobox 1b
chr2_+_32780138 1.47 ENSDART00000082250
zgc:136930
zgc:136930
chr19_-_103289 1.47 ENSDART00000143118
adgrb1b
adhesion G protein-coupled receptor B1b
chr14_+_6159162 1.45 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr3_+_26081343 1.44 ENSDART00000134647
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr15_+_37105986 1.43 ENSDART00000157762
aplp1
amyloid beta (A4) precursor-like protein 1
chr5_-_35301800 1.41 ENSDART00000085142
map1b
microtubule-associated protein 1B
chr16_-_43025885 1.39 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
si:dkey-7j14.5
chr14_-_32016615 1.39 ENSDART00000105761
zic3
zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
chr20_+_34320635 1.38 ENSDART00000153207
ivns1abpa
influenza virus NS1A binding protein a
chr15_-_2657508 1.35 ENSDART00000102086
cldna
claudin a
chr22_+_38194151 1.35 ENSDART00000121965
cp
ceruloplasmin
chr23_-_19953089 1.34 ENSDART00000153828
atp2b3b
ATPase plasma membrane Ca2+ transporting 3b
chr24_-_37877743 1.34 ENSDART00000105658
tmem204
transmembrane protein 204
chr1_+_45080897 1.34 ENSDART00000129819
si:ch211-151p13.8
si:ch211-151p13.8
chr11_+_11230121 1.32 ENSDART00000172438
myom2a
myomesin 2a
chr2_-_20599315 1.32 ENSDART00000114199
si:ch211-267e7.3
si:ch211-267e7.3
chr15_-_21877726 1.31 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr7_-_28696556 1.28 ENSDART00000148822
adgrg1
adhesion G protein-coupled receptor G1
chr13_+_42124566 1.27 ENSDART00000074707
cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr7_-_28148310 1.27 ENSDART00000044208
lmo1
LIM domain only 1
chr23_+_36087219 1.25 ENSDART00000154825
hoxc3a
homeobox C3a
chr19_+_24488403 1.22 ENSDART00000052421
txnipa
thioredoxin interacting protein a
chr22_+_661505 1.22 ENSDART00000149460
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr19_-_12145765 1.22 ENSDART00000032474
pabpc1b
poly A binding protein, cytoplasmic 1 b
chr15_-_26552652 1.21 ENSDART00000152336
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr18_+_17583479 1.21 ENSDART00000186977
ENSDART00000010998
slc12a3
solute carrier family 12 (sodium/chloride transporter), member 3
chr3_+_39568290 1.20 ENSDART00000020741
aldoaa
aldolase a, fructose-bisphosphate, a
chr8_+_23213320 1.20 ENSDART00000032996
ENSDART00000137536
ppdpfa
pancreatic progenitor cell differentiation and proliferation factor a
chr12_-_48477031 1.20 ENSDART00000105176
ndufb8
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8
chr11_-_10770053 1.19 ENSDART00000179213
slc4a10a
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr12_+_7865470 1.19 ENSDART00000161683
BX548028.1

chr16_-_29702447 1.18 ENSDART00000150617
tnfaip8l2b
tumor necrosis factor, alpha-induced protein 8-like 2b
chr14_-_9199968 1.18 ENSDART00000146113
arhgef9b
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr2_-_58201173 1.18 ENSDART00000166282
pnp5b
purine nucleoside phosphorylase 5b
chr14_-_40389699 1.16 ENSDART00000181581
ENSDART00000173398
pcdh19
protocadherin 19
chr10_-_27197044 1.15 ENSDART00000137928
auts2a
autism susceptibility candidate 2a
chr7_-_25895189 1.15 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr23_+_42338325 1.15 ENSDART00000169660
cyp2aa7
cytochrome P450, family 2, subfamily AA, polypeptide 7
chr4_-_22671469 1.14 ENSDART00000050753
cd36
CD36 molecule (thrombospondin receptor)
chr5_-_41834999 1.14 ENSDART00000135772
si:dkey-65b12.6
si:dkey-65b12.6
chr23_-_24488696 1.13 ENSDART00000155593
tmem82
transmembrane protein 82
chr14_-_21064199 1.13 ENSDART00000172099
si:dkey-74k8.3
si:dkey-74k8.3
chr4_+_25627147 1.13 ENSDART00000041965
acot15
acyl-CoA thioesterase 15
chr19_-_32487469 1.12 ENSDART00000050130
gmpr
guanosine monophosphate reductase
chr19_+_47311020 1.12 ENSDART00000138295
ext1c
exostoses (multiple) 1c
chr12_-_30583668 1.12 ENSDART00000153406
casp7
caspase 7, apoptosis-related cysteine peptidase
chr11_+_25259058 1.11 ENSDART00000154109
tp53inp2
tumor protein p53 inducible nuclear protein 2
chr21_+_26071874 1.09 ENSDART00000003001
ENSDART00000146573
rpl23a
ribosomal protein L23a
chr22_+_15624371 1.05 ENSDART00000124868
lpl
lipoprotein lipase
chr21_-_17956739 1.04 ENSDART00000148154
stx2a
syntaxin 2a
chr8_+_45003659 1.04 ENSDART00000132663
si:ch211-163b2.4
si:ch211-163b2.4
chr1_+_50987535 1.04 ENSDART00000140657
mdh1aa
malate dehydrogenase 1Aa, NAD (soluble)
chr12_+_8168272 1.04 ENSDART00000054092
arid5b
AT-rich interaction domain 5B
chr4_+_14360372 1.03 ENSDART00000007103
nuak1a
NUAK family, SNF1-like kinase, 1a
chr22_+_661711 1.03 ENSDART00000113795
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr22_-_36876133 1.02 ENSDART00000147006
kng1
kininogen 1
chr18_-_8885792 1.02 ENSDART00000143619
si:dkey-95h12.1
si:dkey-95h12.1
chr7_+_61480296 1.02 ENSDART00000083255
adam19a
ADAM metallopeptidase domain 19a
chr2_-_24289641 1.01 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myh7l
myosin heavy chain 7-like
chr19_-_12145390 1.00 ENSDART00000143087
pabpc1b
poly A binding protein, cytoplasmic 1 b
chr9_-_1986014 0.99 ENSDART00000142842
hoxd12a
homeobox D12a
chr23_+_25708787 0.99 ENSDART00000060059
rbms2b
RNA binding motif, single stranded interacting protein 2b
chr21_-_17956416 0.98 ENSDART00000026737
stx2a
syntaxin 2a
chr20_+_54738210 0.98 ENSDART00000151399
pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr18_+_48423973 0.98 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr21_-_20341836 0.98 ENSDART00000176689
rbp4l
retinol binding protein 4, like
chr21_+_17956856 0.97 ENSDART00000080431
dnai1.2
dynein, axonemal, intermediate chain 1, paralog 2
chr16_+_55059026 0.96 ENSDART00000109391
LO017815.1
Danio rerio nuclear receptor coactivator 7-like (LOC792958), mRNA.
chr3_-_40301467 0.95 ENSDART00000055186
atp5mf
ATP synthase membrane subunit f
chr4_+_77021784 0.94 ENSDART00000135345
ENSDART00000133855
trpm2
transient receptor potential cation channel, subfamily M, member 2
chr7_-_24204665 0.93 ENSDART00000167141
gmpr2
guanosine monophosphate reductase 2
chr1_+_54911458 0.93 ENSDART00000089603
golga7ba
golgin A7 family, member Ba
chr20_-_9760424 0.93 ENSDART00000104936
si:dkey-63j12.4
si:dkey-63j12.4
chr24_-_17023392 0.92 ENSDART00000106058
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr15_-_20916251 0.91 ENSDART00000134053
usp2a
ubiquitin specific peptidase 2a
chr6_+_22337081 0.91 ENSDART00000128047
ENSDART00000138930
uqcrc1
ubiquinol-cytochrome c reductase core protein 1
chr23_-_5683147 0.90 ENSDART00000102766
ENSDART00000067351
tnnt2a
troponin T type 2a (cardiac)
chr2_-_27900518 0.90 ENSDART00000109561
ENSDART00000077720
zgc:163121
zgc:163121
chr6_+_25257728 0.90 ENSDART00000162581
kyat3
kynurenine aminotransferase 3
chr6_+_8176486 0.90 ENSDART00000193308
nfil3-5
nuclear factor, interleukin 3 regulated, member 5
chr22_+_8313513 0.90 ENSDART00000181169
ENSDART00000103911
CABZ01077217.1

chr21_-_16114061 0.88 ENSDART00000035742
cyb561a3b
cytochrome b561 family, member A3b
chr1_+_44941031 0.88 ENSDART00000141145
si:dkey-9i23.16
si:dkey-9i23.16
chr13_-_2215213 0.87 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr20_+_26095530 0.86 ENSDART00000139350
syne1a
spectrin repeat containing, nuclear envelope 1a
chr3_+_43460696 0.86 ENSDART00000164581
galr2b
galanin receptor 2b
chr2_-_5199431 0.86 ENSDART00000063384
phb2a
prohibitin 2a
chr25_-_10564721 0.86 ENSDART00000154776
galn
galanin/GMAP prepropeptide
chr10_+_22775253 0.85 ENSDART00000190141
tmem88a
transmembrane protein 88 a
chr7_-_33351485 0.85 ENSDART00000146420
anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr22_+_5478353 0.85 ENSDART00000160596
tppp
tubulin polymerization promoting protein
chr18_-_24996634 0.85 ENSDART00000170210
si:ch211-196l7.4
si:ch211-196l7.4
chr14_-_12253309 0.84 ENSDART00000115101
myot
myotilin
chr10_-_42685512 0.84 ENSDART00000081347
stc1l
stanniocalcin 1, like
chr6_+_7250824 0.84 ENSDART00000177226
dzip1
DAZ interacting zinc finger protein 1
chr9_+_33145522 0.83 ENSDART00000005879
atp5po
ATP synthase peripheral stalk subunit OSCP
chr13_-_13294847 0.83 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr19_+_18799319 0.83 ENSDART00000171843
ddah2
dimethylarginine dimethylaminohydrolase 2
chr8_+_10304981 0.82 ENSDART00000160766
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr22_+_9472814 0.82 ENSDART00000112125
ENSDART00000138850
cacna2d2b
calcium channel, voltage-dependent, alpha 2/delta subunit 2b
chr10_-_16065185 0.81 ENSDART00000187266
si:dkey-184a18.5
si:dkey-184a18.5
chr15_+_20403903 0.80 ENSDART00000134182
cox7a1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr20_+_40237441 0.79 ENSDART00000168928
si:ch211-199i15.5
si:ch211-199i15.5
chr3_-_32859335 0.78 ENSDART00000158916
si:dkey-16l2.20
si:dkey-16l2.20
chr25_-_21816269 0.78 ENSDART00000152014
zgc:158222
zgc:158222
chr5_+_38276582 0.78 ENSDART00000158532
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr21_-_20342096 0.78 ENSDART00000065659
rbp4l
retinol binding protein 4, like
chr5_-_32445835 0.78 ENSDART00000170919
ncs1a
neuronal calcium sensor 1a
chr7_-_24204200 0.78 ENSDART00000087298
gmpr2
guanosine monophosphate reductase 2
chr21_-_26071142 0.77 ENSDART00000004740
rab34b
RAB34, member RAS oncogene family b
chr9_+_22003942 0.76 ENSDART00000091013
si:dkey-57a22.15
si:dkey-57a22.15
chr10_+_42374770 0.76 ENSDART00000020000
COX5B
zgc:86599
chr4_-_5247335 0.74 ENSDART00000050221
atp6v1e1b
ATPase H+ transporting V1 subunit E1b
chr14_-_29826659 0.74 ENSDART00000138413
sorbs2b
sorbin and SH3 domain containing 2b
chr24_+_26432541 0.74 ENSDART00000105784
ENSDART00000122554
cldn11b
claudin 11b
chr3_-_21280373 0.74 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr5_-_63109232 0.74 ENSDART00000115128
usp2b
ubiquitin specific peptidase 2b
chr4_-_23839789 0.73 ENSDART00000143571
usp6nl
USP6 N-terminal like
chr7_+_20467549 0.73 ENSDART00000173724
si:dkey-33c9.8
si:dkey-33c9.8
chr16_+_32559821 0.73 ENSDART00000093250
pou3f2b
POU class 3 homeobox 2b
chr6_+_41099787 0.72 ENSDART00000186884
fkbp5
FK506 binding protein 5
chr12_+_39203745 0.72 ENSDART00000153661
si:dkeyp-106c3.2
si:dkeyp-106c3.2
chr9_+_4429593 0.72 ENSDART00000184855
FP015810.1

chr6_-_28980756 0.72 ENSDART00000014661
glmnb
glomulin, FKBP associated protein b
chr7_+_20475788 0.72 ENSDART00000171155
si:dkey-19b23.13
si:dkey-19b23.13
chr16_+_32749591 0.72 ENSDART00000136759
prdm13
PR domain containing 13
chr25_-_13188678 0.71 ENSDART00000125754
si:ch211-147m6.1
si:ch211-147m6.1
chr12_+_34896956 0.71 ENSDART00000055415
prph2a
peripherin 2a (retinal degeneration, slow)
chr18_-_26101800 0.70 ENSDART00000004692
idh2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr19_-_42945965 0.70 ENSDART00000142858
dclk3
doublecortin-like kinase 3
chr6_+_48618512 0.69 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr23_+_18722915 0.69 ENSDART00000025057
myh7bb
myosin, heavy chain 7B, cardiac muscle, beta b
chr8_-_17926814 0.69 ENSDART00000147344
lhx8b
LIM homeobox 8b
chr18_-_8312848 0.69 ENSDART00000092033
mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
chr10_-_32524771 0.69 ENSDART00000066793
dgat2
diacylglycerol O-acyltransferase 2
chr23_+_18722715 0.68 ENSDART00000137438
myh7bb
myosin, heavy chain 7B, cardiac muscle, beta b
chr4_+_2620751 0.68 ENSDART00000013924
gpr22a
G protein-coupled receptor 22a
chr7_-_12821277 0.68 ENSDART00000091584
zgc:158785
zgc:158785
chr22_+_7486867 0.68 ENSDART00000034586
CELA1 (1 of many)
zgc:112302
chr19_+_37701450 0.68 ENSDART00000087694
thsd7aa
thrombospondin, type I, domain containing 7Aa
chr8_-_39903803 0.68 ENSDART00000012391
cabp1a
calcium binding protein 1a
chr7_+_34688527 0.67 ENSDART00000108473
plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr6_-_50404732 0.66 ENSDART00000055510
romo1
reactive oxygen species modulator 1
chr8_+_1769475 0.65 ENSDART00000079073
serpind1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr10_-_29101715 0.65 ENSDART00000149674
ENSDART00000171194
ENSDART00000192019
si:ch211-103f14.3
si:ch211-103f14.3
chr17_-_31058900 0.65 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
eml1
echinoderm microtubule associated protein like 1
chr25_+_13791627 0.65 ENSDART00000159278
zgc:92873
zgc:92873
chr20_+_43942278 0.64 ENSDART00000100571
clic5b
chloride intracellular channel 5b
chr12_+_15622621 0.64 ENSDART00000079784
plcd3b
phospholipase C, delta 3b
chr9_-_54344405 0.64 ENSDART00000182939
CT998556.1

chr23_-_33750135 0.64 ENSDART00000187641
bin2a
bridging integrator 2a
chr19_+_14059349 0.64 ENSDART00000166230
tpbga
trophoblast glycoprotein a
chr9_+_17348745 0.64 ENSDART00000147488
slain1a
SLAIN motif family, member 1a
chr8_+_19514294 0.64 ENSDART00000170622
si:ch73-281k2.5
si:ch73-281k2.5
chr11_+_23704410 0.64 ENSDART00000112655
nfasca
neurofascin homolog (chicken) a
chr1_-_5455498 0.63 ENSDART00000040368
ENSDART00000114035
mnx2b
motor neuron and pancreas homeobox 2b
chr23_+_36083529 0.63 ENSDART00000053295
ENSDART00000130260
hoxc10a
homeobox C10a
chr20_-_40729364 0.62 ENSDART00000101014
cx32.2
connexin 32.2
chr21_-_12119711 0.62 ENSDART00000131538
celf4
CUGBP, Elav-like family member 4
chr15_+_1004680 0.62 ENSDART00000157310
si:dkey-77f5.8
si:dkey-77f5.8
chr25_-_35599887 0.61 ENSDART00000153827
clpxb
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr23_+_6272638 0.61 ENSDART00000190366
syt2a
synaptotagmin IIa
chr14_+_8343498 0.60 ENSDART00000164551
nrg2b
neuregulin 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of nr5a1a+nr5a2+nr5a5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.6 2.3 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.4 3.1 GO:0034389 lipid particle organization(GO:0034389)
0.4 1.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.4 1.7 GO:0009957 epidermal cell fate specification(GO:0009957)
0.4 5.2 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.4 1.5 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.4 1.4 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.3 1.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 1.5 GO:2000379 positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.3 0.9 GO:1901296 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.3 0.8 GO:0006097 glyoxylate cycle(GO:0006097)
0.3 1.3 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.2 1.7 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.2 2.1 GO:0042438 melanin biosynthetic process(GO:0042438)
0.2 0.9 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.2 1.1 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.2 1.3 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2 1.0 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 0.6 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 1.2 GO:0071800 podosome assembly(GO:0071800)
0.2 0.5 GO:0070126 mitochondrial translational termination(GO:0070126)
0.2 0.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 2.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.6 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 1.0 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.8 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.4 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 1.3 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.5 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 0.5 GO:0035790 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.1 0.5 GO:0035994 response to muscle stretch(GO:0035994)
0.1 2.8 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.5 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.5 GO:1990544 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 1.2 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.1 0.5 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 1.0 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.4 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 1.4 GO:0001840 neural plate development(GO:0001840)
0.1 0.4 GO:0015677 copper ion import(GO:0015677)
0.1 1.1 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 1.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.8 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 2.4 GO:0021884 forebrain neuron development(GO:0021884)
0.1 7.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.8 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.7 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.5 GO:0006788 heme oxidation(GO:0006788)
0.1 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.5 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.1 1.0 GO:0035094 response to nicotine(GO:0035094)
0.1 0.3 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 2.1 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.3 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 2.0 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.4 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.5 GO:0060114 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 2.7 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.1 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.2 GO:0001966 thigmotaxis(GO:0001966)
0.1 1.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 1.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0030719 P granule organization(GO:0030719)
0.0 1.1 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.3 GO:0035889 otolith tethering(GO:0035889)
0.0 0.4 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 2.0 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.3 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.4 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.8 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.2 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.6 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.8 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.4 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 1.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.8 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 1.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.8 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.2 GO:0001841 neural tube formation(GO:0001841)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.7 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.6 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 1.2 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 1.5 GO:0033339 pectoral fin development(GO:0033339)
0.0 2.1 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.9 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.4 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 2.6 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.7 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 1.7 GO:1990266 neutrophil migration(GO:1990266)
0.0 0.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 1.6 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 1.0 GO:0006821 chloride transport(GO:0006821)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:1902560 GMP reductase complex(GO:1902560)
0.4 2.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.4 1.4 GO:0031673 H zone(GO:0031673)
0.2 2.4 GO:0042627 chylomicron(GO:0042627)
0.2 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.2 1.2 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.5 GO:0032433 filopodium tip(GO:0032433)
0.1 2.1 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 3.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 2.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.0 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.3 GO:0031430 M band(GO:0031430)
0.1 0.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.0 GO:0045259 proton-transporting ATP synthase complex(GO:0045259)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 3.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 2.0 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.7 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.8 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0098803 respiratory chain complex(GO:0098803)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 4.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0098753 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.0 0.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.1 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.9 GO:0005861 troponin complex(GO:0005861)
0.0 2.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 23.6 GO:0005576 extracellular region(GO:0005576)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.8 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.4 5.2 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.4 1.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.3 1.8 GO:0004104 cholinesterase activity(GO:0004104)
0.3 1.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.3 1.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3 0.8 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.3 1.3 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 1.8 GO:0034632 retinol transporter activity(GO:0034632)
0.2 0.7 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.2 0.9 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.2 0.9 GO:0005521 lamin binding(GO:0005521)
0.2 1.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 1.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.2 2.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 1.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.9 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.4 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.5 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 2.4 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.5 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.4 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.9 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.2 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.0 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.7 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.4 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 4.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 1.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.8 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.4 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.6 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 1.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 4.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 5.4 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.6 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 1.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 4.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 4.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 2.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 1.2 GO:0042802 identical protein binding(GO:0042802)
0.0 3.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 3.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.4 PID REELIN PATHWAY Reelin signaling pathway
0.1 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 3.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.8 PID FGF PATHWAY FGF signaling pathway
0.0 0.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 5.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 1.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.6 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 2.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.7 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.8 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements