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PRJNA195909:zebrafish embryo and larva development

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Results for nr6a1a

Z-value: 1.29

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Transcription factors associated with nr6a1a

Gene Symbol Gene ID Gene Info
nr6a1a
ENSDARG00000101508 nuclear receptor subfamily 6, group A, member 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr6a1adr11_v1_chr8_-_52909850_52909850-0.617.9e-02Click!

Activity profile of nr6a1a motif

Sorted Z-values of nr6a1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22188117 1.63 ENSDART00000132890
crygm2d17
crystallin, gamma M2d17
chr2_-_37210397 1.24 ENSDART00000084938
apoda.1
apolipoprotein Da, duplicate 1
chr16_-_45235947 1.09 ENSDART00000164436
si:dkey-33i11.4
si:dkey-33i11.4
chr14_-_33454595 0.85 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr6_+_6491013 0.84 ENSDART00000140827
bcl11ab
B cell CLL/lymphoma 11Ab
chr16_+_24626448 0.81 ENSDART00000153591
si:dkey-56f14.7
si:dkey-56f14.7
chr4_-_17409533 0.79 ENSDART00000011943
pah
phenylalanine hydroxylase
chr11_+_45287541 0.75 ENSDART00000165321
ENSDART00000173116
pycr1b
pyrroline-5-carboxylate reductase 1b
chr10_-_17284055 0.66 ENSDART00000167464
GNAZ
G protein subunit alpha z
chr17_+_25414033 0.66 ENSDART00000001691
tdh2
L-threonine dehydrogenase 2
chr19_-_47455944 0.64 ENSDART00000190005
tfap2e
transcription factor AP-2 epsilon
chr17_+_18117029 0.62 ENSDART00000154646
ENSDART00000179739
bcl11ba
B cell CLL/lymphoma 11Ba
chr20_-_43771871 0.61 ENSDART00000153304
matn3a
matrilin 3a
chr12_+_45676667 0.61 ENSDART00000016553
si:ch73-111m19.2
si:ch73-111m19.2
chr10_-_42685512 0.59 ENSDART00000081347
stc1l
stanniocalcin 1, like
chr7_-_31618166 0.59 ENSDART00000111388
igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr23_+_28092083 0.59 ENSDART00000053958
c1galt1a
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr24_-_17047918 0.58 ENSDART00000020204
msrb2
methionine sulfoxide reductase B2
chr12_+_30788912 0.55 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr17_+_18117358 0.55 ENSDART00000144894
bcl11ba
B cell CLL/lymphoma 11Ba
chr20_+_4392687 0.54 ENSDART00000187271
im:7142702
im:7142702
chr25_+_7492663 0.54 ENSDART00000166496
cat
catalase
chr23_-_35756115 0.53 ENSDART00000043429
jph2
junctophilin 2
chr11_-_97817 0.52 ENSDART00000092903
elmo2
engulfment and cell motility 2
chr19_-_5103313 0.52 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr5_-_41834999 0.51 ENSDART00000135772
si:dkey-65b12.6
si:dkey-65b12.6
chr6_+_41099787 0.50 ENSDART00000186884
fkbp5
FK506 binding protein 5
chr6_+_39836474 0.50 ENSDART00000112637
smarcc2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr19_-_5135345 0.49 ENSDART00000151787
gnb3b
guanine nucleotide binding protein (G protein), beta polypeptide 3b
chr3_-_20091964 0.49 ENSDART00000029386
ENSDART00000020253
ENSDART00000124326
slc4a1a
solute carrier family 4 (anion exchanger), member 1a (Diego blood group)
chr4_+_6643421 0.49 ENSDART00000099462
gpr85
G protein-coupled receptor 85
chr25_-_13188678 0.47 ENSDART00000125754
si:ch211-147m6.1
si:ch211-147m6.1
chr20_-_23219964 0.46 ENSDART00000144933
dcun1d4
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
chr19_-_42571829 0.45 ENSDART00000102606
zgc:103438
zgc:103438
chr14_-_36412473 0.44 ENSDART00000128244
ENSDART00000138376
asb5a
ankyrin repeat and SOCS box containing 5a
chr10_-_11383900 0.44 ENSDART00000101045
plac8.1
placenta-specific 8, tandem duplicate 1
chr2_+_30916188 0.43 ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr19_-_5103141 0.43 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr16_-_17197546 0.43 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr14_-_3174570 0.43 ENSDART00000163585
csf1ra
colony stimulating factor 1 receptor, a
chr15_+_46386261 0.42 ENSDART00000191793
igsf11
immunoglobulin superfamily member 11
chr13_-_21688176 0.42 ENSDART00000063825
sprn
shadow of prion protein
chr2_-_22286828 0.41 ENSDART00000168653
fam110b
family with sequence similarity 110, member B
chr24_+_20960216 0.41 ENSDART00000133008
si:ch211-161h7.8
si:ch211-161h7.8
chr25_+_34576067 0.40 ENSDART00000157519
trpm1b
transient receptor potential cation channel, subfamily M, member 1b
chr5_-_37103487 0.40 ENSDART00000149211
il13ra2
interleukin 13 receptor, alpha 2
chr3_-_39305291 0.39 ENSDART00000102674
plcd3a
phospholipase C, delta 3a
chr19_-_103289 0.39 ENSDART00000143118
adgrb1b
adhesion G protein-coupled receptor B1b
chr5_-_69004007 0.39 ENSDART00000137443
ank1a
ankyrin 1, erythrocytic a
chr21_+_15713097 0.39 ENSDART00000015841
gstt1b
glutathione S-transferase theta 1b
chr3_+_13469704 0.39 ENSDART00000166806
zgc:77748
zgc:77748
chr10_+_37927100 0.38 ENSDART00000172548
bhlha9
basic helix-loop-helix family, member a9
chr18_+_36631923 0.38 ENSDART00000098980
znf296
zinc finger protein 296
chr5_-_41124241 0.37 ENSDART00000083561
mtmr12
myotubularin related protein 12
chr18_+_8912113 0.36 ENSDART00000147467
tmem243a
transmembrane protein 243, mitochondrial a
chr13_-_1085961 0.36 ENSDART00000171872
ENSDART00000166598
plek
pleckstrin
chr10_-_19801651 0.36 ENSDART00000080430
gfra2b
GDNF family receptor alpha 2b
chr8_+_19514294 0.35 ENSDART00000170622
si:ch73-281k2.5
si:ch73-281k2.5
chr1_-_55785722 0.35 ENSDART00000142069
ENSDART00000043933
ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr5_-_41531629 0.35 ENSDART00000051082
akr1a1a
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr11_-_7320211 0.35 ENSDART00000091664
apc2
adenomatosis polyposis coli 2
chr25_+_33939728 0.35 ENSDART00000148537
roraa
RAR-related orphan receptor A, paralog a
chr9_-_21238159 0.35 ENSDART00000146764
ENSDART00000102143
cox17
COX17 cytochrome c oxidase copper chaperone
chr7_-_58130703 0.35 ENSDART00000172082
ank2b
ankyrin 2b, neuronal
chr9_+_31795343 0.35 ENSDART00000139584
itgbl1
integrin, beta-like 1
chr10_-_42131408 0.34 ENSDART00000076693
stambpa
STAM binding protein a
chr6_+_48618512 0.33 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr25_-_35963158 0.33 ENSDART00000153612
snx20
sorting nexin 20
chr9_-_21238616 0.33 ENSDART00000191840
ENSDART00000189127
cox17
COX17 cytochrome c oxidase copper chaperone
chr16_+_14033121 0.33 ENSDART00000135844
rusc1
RUN and SH3 domain containing 1
chr3_+_39540014 0.32 ENSDART00000074848
zgc:165423
zgc:165423
chr10_-_24371312 0.32 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr1_-_50859053 0.32 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr12_-_4346085 0.32 ENSDART00000112433
ca15c
carbonic anhydrase XV c
chr23_-_19953089 0.32 ENSDART00000153828
atp2b3b
ATPase plasma membrane Ca2+ transporting 3b
chr13_-_2215213 0.31 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr3_-_58455289 0.31 ENSDART00000052179
cdr2a
cerebellar degeneration-related protein 2a
chr1_-_23110740 0.30 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr1_-_45553602 0.30 ENSDART00000143664
grin2bb
glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b
chr11_-_27874116 0.30 ENSDART00000180579
eif4g3a
eukaryotic translation initiation factor 4 gamma, 3a
chr1_-_22652424 0.29 ENSDART00000036797
uchl1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr2_-_24289641 0.29 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myh7l
myosin heavy chain 7-like
chr24_-_10828560 0.28 ENSDART00000132282
fam49bb
family with sequence similarity 49, member Bb
chr3_-_7656059 0.28 ENSDART00000170917
junbb
JunB proto-oncogene, AP-1 transcription factor subunit b
chr9_-_54001502 0.28 ENSDART00000085253
mid1
midline 1
chr19_-_32487469 0.28 ENSDART00000050130
gmpr
guanosine monophosphate reductase
chr25_+_14092871 0.28 ENSDART00000067239
guca1g
guanylate cyclase activator 1g
chr8_+_44703864 0.27 ENSDART00000016225
star
steroidogenic acute regulatory protein
chr15_-_26549693 0.27 ENSDART00000186432
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr6_-_30932078 0.27 ENSDART00000028612
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr21_-_22737228 0.27 ENSDART00000151366
fbxo40.2
F-box protein 40, tandem duplicate 2
chr10_+_43117661 0.26 ENSDART00000024644
ENSDART00000186932
xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr16_+_10776688 0.26 ENSDART00000161969
ENSDART00000172657
atp1a3b
ATPase Na+/K+ transporting subunit alpha 3b
chr19_+_23919096 0.26 ENSDART00000090200
snapin
SNAP-associated protein
chr7_-_15370042 0.26 ENSDART00000128183
ANPEP
si:ch211-276a23.5
chr18_+_8340886 0.26 ENSDART00000081132
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr3_-_46403778 0.26 ENSDART00000074422
cdip1
cell death-inducing p53 target 1
chr15_+_19682013 0.25 ENSDART00000127368
si:dkey-4p15.5
si:dkey-4p15.5
chr2_+_38924975 0.25 ENSDART00000109219
rem2
RAS (RAD and GEM)-like GTP binding 2
chr13_-_42724645 0.25 ENSDART00000046066
capn1a
calpain 1, (mu/I) large subunit a
chr2_+_24868010 0.25 ENSDART00000078838
rab3aa
RAB3A, member RAS oncogene family, a
chr24_-_37877743 0.24 ENSDART00000105658
tmem204
transmembrane protein 204
chr2_+_21452822 0.24 ENSDART00000169028
afg3l2
AFG3-like AAA ATPase 2
chr11_+_24966182 0.24 ENSDART00000185088
sulf2a
sulfatase 2a
chr11_+_15878343 0.23 ENSDART00000167191
ENSDART00000171862
ENSDART00000163992
ENSDART00000170065
pank4
pantothenate kinase 4
chr15_-_28247583 0.23 ENSDART00000112967
rilp
Rab interacting lysosomal protein
chr23_+_36653376 0.23 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr21_+_34929598 0.22 ENSDART00000135806
si:dkey-71d15.2
si:dkey-71d15.2
chr18_-_226800 0.22 ENSDART00000165180
tarsl2
threonyl-tRNA synthetase-like 2
chr3_-_34279109 0.22 ENSDART00000183255
tnrc6c1
trinucleotide repeat containing 6C1
chr9_-_46276626 0.22 ENSDART00000165238
hdac4
histone deacetylase 4
chr16_+_50741154 0.22 ENSDART00000101627
IGLON5
zgc:110372
chr7_+_17096281 0.21 ENSDART00000035558
htatip2
HIV-1 Tat interactive protein 2
chr2_+_7818368 0.21 ENSDART00000007068
kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr6_-_47246948 0.21 ENSDART00000162435
grm4
glutamate receptor, metabotropic 4
chr1_+_50085440 0.21 ENSDART00000018469
ENSDART00000134988
npnt
nephronectin
chr1_+_17527342 0.21 ENSDART00000139702
ENSDART00000140076
ENSDART00000005593
casp3a
caspase 3, apoptosis-related cysteine peptidase a
chr8_-_42238543 0.21 ENSDART00000062697
gfra2a
GDNF family receptor alpha 2a
chr5_+_45000597 0.20 ENSDART00000051146
dmrt3a
doublesex and mab-3 related transcription factor 3a
chr17_+_38566717 0.20 ENSDART00000145147
sptb
spectrin, beta, erythrocytic
chr16_+_43347966 0.20 ENSDART00000171308
zmp:0000000930
zmp:0000000930
chr16_-_12319822 0.20 ENSDART00000127453
ENSDART00000184526
trpv6
transient receptor potential cation channel, subfamily V, member 6
chr9_-_48700806 0.20 ENSDART00000026210
rdh1
retinol dehydrogenase 1
chr21_-_23110841 0.20 ENSDART00000147896
ENSDART00000003076
ENSDART00000184925
ENSDART00000190386
usp28
ubiquitin specific peptidase 28
chr5_-_41841675 0.20 ENSDART00000141683
si:dkey-65b12.6
si:dkey-65b12.6
chr3_-_30609659 0.20 ENSDART00000182516
ENSDART00000187047
ENSDART00000110597
syt3
synaptotagmin III
chr1_-_22726233 0.20 ENSDART00000140920
prom1b
prominin 1 b
chr2_+_52232630 0.20 ENSDART00000006216
plpp2a
phospholipid phosphatase 2a
chr22_-_22337382 0.20 ENSDART00000144684
si:ch211-129c21.1
si:ch211-129c21.1
chr12_-_30583668 0.19 ENSDART00000153406
casp7
caspase 7, apoptosis-related cysteine peptidase
chr17_-_39880725 0.19 ENSDART00000184030
zmp:0000000545
zmp:0000000545
chr6_-_29051773 0.19 ENSDART00000190508
ENSDART00000180191
ENSDART00000111682
evi5b
ecotropic viral integration site 5b
chr8_+_26125218 0.19 ENSDART00000145095
celsr3
cadherin, EGF LAG seven-pass G-type receptor 3
chr8_-_29713595 0.19 ENSDART00000131988
ENSDART00000077637
mpeg1.1
macrophage expressed 1, tandem duplicate 1
chr21_+_43669943 0.19 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr4_-_4932619 0.19 ENSDART00000103293
ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr4_+_9478500 0.19 ENSDART00000030738
lmf2b
lipase maturation factor 2b
chr11_+_27133560 0.19 ENSDART00000158411
hdac11
histone deacetylase 11
chr10_-_1733937 0.18 ENSDART00000144216
gal3st1b
galactose-3-O-sulfotransferase 1b
chr13_-_11763186 0.18 ENSDART00000102381
ENSDART00000187819
ube2d3
ubiquitin-conjugating enzyme E2D 3
chr21_-_40174647 0.18 ENSDART00000183738
ENSDART00000076840
ENSDART00000145109
slco2b1
solute carrier organic anion transporter family, member 2B1
chr16_-_12809873 0.18 ENSDART00000146997
ENSDART00000178291
ENSDART00000007842
isoc2
isochorismatase domain containing 2
chr21_-_17956416 0.18 ENSDART00000026737
stx2a
syntaxin 2a
chr1_+_34243650 0.18 ENSDART00000147201
slc5a7a
solute carrier family 5 (sodium/choline cotransporter), member 7a
chr17_-_35238359 0.18 ENSDART00000005784
itgb1bp1
integrin beta 1 binding protein 1
chr1_+_50085640 0.18 ENSDART00000158988
ENSDART00000165973
npnt
nephronectin
chr5_-_28606916 0.17 ENSDART00000026107
ENSDART00000137717
tnc
tenascin C
chr24_-_28245872 0.17 ENSDART00000167861
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr6_+_52235441 0.17 ENSDART00000056319
cox6c
cytochrome c oxidase subunit VIc
chr11_-_18799827 0.17 ENSDART00000185438
ENSDART00000189116
ENSDART00000180504
pfkfb2b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr25_-_12635371 0.17 ENSDART00000162463
zcchc14
zinc finger, CCHC domain containing 14
chr16_-_46567344 0.17 ENSDART00000127721
si:dkey-152b24.7
si:dkey-152b24.7
chr5_+_22579975 0.17 ENSDART00000080877
tnfsf10l4
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr14_+_32838110 0.17 ENSDART00000158077
arr3b
arrestin 3b, retinal (X-arrestin)
chr5_-_50992690 0.16 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
hmgcra
3-hydroxy-3-methylglutaryl-CoA reductase a
chr6_+_42338309 0.16 ENSDART00000015277
gpx1b
glutathione peroxidase 1b
chr23_+_16633951 0.16 ENSDART00000109537
ENSDART00000193323
snphb
syntaphilin b
chr21_-_17956739 0.16 ENSDART00000148154
stx2a
syntaxin 2a
chr8_+_19356072 0.16 ENSDART00000063272
mpeg1.2
macrophage expressed 1, tandem duplicate 2
chr2_-_20120904 0.16 ENSDART00000186002
ENSDART00000124724
dpydb
dihydropyrimidine dehydrogenase b
chr9_-_10805231 0.16 ENSDART00000193913
ENSDART00000078348
si:ch1073-416j23.1
si:ch1073-416j23.1
chr20_-_28404362 0.16 ENSDART00000055932
ENSDART00000188161
pigh
phosphatidylinositol glycan anchor biosynthesis, class H
chr7_+_65261354 0.16 ENSDART00000168388
bco1
beta-carotene oxygenase 1
chr21_-_43040780 0.15 ENSDART00000187037
jakmip2
janus kinase and microtubule interacting protein 2
chr8_+_29742237 0.15 ENSDART00000133955
ENSDART00000020621
mapk4
mitogen-activated protein kinase 4
chr16_-_18960613 0.15 ENSDART00000183197
fhod3b
formin homology 2 domain containing 3b
chr1_+_44711446 0.15 ENSDART00000193481
ENSDART00000003895
ssrp1b
structure specific recognition protein 1b
chr3_+_53511936 0.14 ENSDART00000177083
zmp:0000001048
zmp:0000001048
chr5_+_9428876 0.14 ENSDART00000081791
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr7_+_20383841 0.14 ENSDART00000052906
si:dkey-33c9.6
si:dkey-33c9.6
chr22_-_6229275 0.14 ENSDART00000146045
ENSDART00000179730
si:ch211-274k16.2
si:ch211-274k16.2
chr20_-_30931139 0.14 ENSDART00000006778
ENSDART00000146376
acat2
acetyl-CoA acetyltransferase 2
chr9_-_10804796 0.14 ENSDART00000134911
si:ch1073-416j23.1
si:ch1073-416j23.1
chr13_+_33055548 0.14 ENSDART00000137315
rdh12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr12_+_30653047 0.14 ENSDART00000148562
thbs2b
thrombospondin 2b
chr13_-_30662403 0.14 ENSDART00000012457
si:dkey-275b16.2
si:dkey-275b16.2
chr8_+_3820134 0.14 ENSDART00000122454
citb
citron rho-interacting serine/threonine kinase b
chr20_-_14665002 0.14 ENSDART00000152816
scrn2
secernin 2
chr2_+_51028269 0.14 ENSDART00000161254
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr5_-_9090178 0.14 ENSDART00000091472
kcnv2b
potassium channel, subfamily V, member 2b
chr25_-_12804450 0.14 ENSDART00000169717
ca5a
carbonic anhydrase Va
chr10_-_39321367 0.14 ENSDART00000129647
smtlb
somatolactin beta
chr21_-_32374656 0.14 ENSDART00000112550
mapk9
mitogen-activated protein kinase 9
chr12_+_34896956 0.13 ENSDART00000055415
prph2a
peripherin 2a (retinal degeneration, slow)
chr6_+_39506043 0.13 ENSDART00000086260
CR388364.1

chr18_-_26510545 0.13 ENSDART00000135133
FRMD5
si:ch211-69m14.1
chr18_+_10689772 0.13 ENSDART00000126441
lepa
leptin a
chr14_+_4178236 0.13 ENSDART00000162015
slc25a51b
solute carrier family 25, member 51b
chr17_-_40956035 0.13 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr15_+_22722684 0.13 ENSDART00000156760
grik4
glutamate receptor, ionotropic, kainate 4
chr24_+_17334682 0.13 ENSDART00000018868
pdia4
protein disulfide isomerase family A, member 4
chr6_-_10835849 0.13 ENSDART00000005903
ENSDART00000135065
atp5mc3b
ATP synthase membrane subunit c locus 3b
chr5_+_6892195 0.13 ENSDART00000048201
gb:cr929477
expressed sequence CR929477
chr16_-_17162485 0.13 ENSDART00000123011
iffo1b
intermediate filament family orphan 1b
chr22_-_5933844 0.13 ENSDART00000163370
ENSDART00000189331
si:rp71-36a1.2
si:rp71-36a1.2
chr15_+_19681718 0.12 ENSDART00000164803
si:dkey-4p15.5
si:dkey-4p15.5
chr7_-_1918971 0.12 ENSDART00000181759
CABZ01040626.1

chr1_+_17527931 0.12 ENSDART00000131927
casp3a
caspase 3, apoptosis-related cysteine peptidase a
chr9_+_41156818 0.12 ENSDART00000105764
ENSDART00000147052
stat4
signal transducer and activator of transcription 4
chr4_+_7827261 0.12 ENSDART00000129568
phyh
phytanoyl-CoA 2-hydroxylase

Network of associatons between targets according to the STRING database.

First level regulatory network of nr6a1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.2 1.0 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 0.5 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.6 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 1.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.1 0.3 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.4 GO:0071674 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) regulation of odontogenesis(GO:0042481) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.1 0.4 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.1 0.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.7 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.2 GO:0046688 response to copper ion(GO:0046688)
0.1 0.8 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 0.4 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.1 0.2 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.1 0.2 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.1 0.2 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 0.2 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.2 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 1.2 GO:0007568 aging(GO:0007568)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0019482 uracil catabolic process(GO:0006212) beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483) uracil metabolic process(GO:0019860)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.3 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.1 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.1 GO:0016037 light absorption(GO:0016037)
0.0 0.2 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.2 GO:0046661 male sex differentiation(GO:0046661)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.3 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.3 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.3 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.8 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.0 GO:0061438 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.4 GO:0050821 protein stabilization(GO:0050821)
0.0 0.3 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.0 0.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0071914 prominosome(GO:0071914)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:1990071 TRAPPII protein complex(GO:1990071)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.7 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.2 0.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.6 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.6 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.1 0.7 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.7 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.6 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.4 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.3 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.3 GO:0005521 lamin binding(GO:0005521)
0.1 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.5 GO:0004096 catalase activity(GO:0004096)
0.1 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.5 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide