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PRJNA195909:zebrafish embryo and larva development

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Results for nrf1

Z-value: 5.08

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Transcription factors associated with nrf1

Gene Symbol Gene ID Gene Info
nrf1
ENSDARG00000000018 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nrf1dr11_v1_chr4_-_15103646_151036960.713.1e-02Click!

Activity profile of nrf1 motif

Sorted Z-values of nrf1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_22320738 6.92 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr25_+_22319940 6.11 ENSDART00000154065
ENSDART00000153492
ENSDART00000024866
ENSDART00000154376
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr13_-_2336584 5.36 ENSDART00000113692
tceb3l
transcription elongation factor B (SIII), polypeptide 3, like
chr5_+_62319217 5.32 ENSDART00000050879
pho
phoenix
chr15_+_44201056 5.17 ENSDART00000162433
ENSDART00000148336
CU655961.4

chr12_-_30359498 5.04 ENSDART00000152981
ENSDART00000189988
tdrd1
tudor domain containing 1
chr24_-_42072886 4.94 ENSDART00000171389
CABZ01095370.1

chr12_-_30359031 4.91 ENSDART00000192628
tdrd1
tudor domain containing 1
chr15_-_45538773 4.88 ENSDART00000113494
MB21D2
Mab-21 domain containing 2
chr11_-_6452444 4.78 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr2_+_29997043 4.67 ENSDART00000139566
ENSDART00000151848
rbm33b
RNA binding motif protein 33b
chr15_-_28587147 4.57 ENSDART00000156049
ssh2a
slingshot protein phosphatase 2a
chr2_+_29996650 4.54 ENSDART00000138050
ENSDART00000141026
rbm33b
RNA binding motif protein 33b
chr12_+_47081783 4.52 ENSDART00000158568
mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr7_+_57089354 4.45 ENSDART00000140702
scamp2l
secretory carrier membrane protein 2, like
chr20_-_182841 4.26 ENSDART00000064546
si:ch211-241j12.3
si:ch211-241j12.3
chr23_+_45845159 4.24 ENSDART00000023944
lmnl3
lamin L3
chr14_+_14806851 4.15 ENSDART00000169235
fhdc2
FH2 domain containing 2
chr12_-_9468618 4.14 ENSDART00000152737
ENSDART00000091519
pgap3
post-GPI attachment to proteins 3
chr13_+_20524921 4.11 ENSDART00000081385
ccdc172
coiled-coil domain containing 172
chr25_+_6266009 4.10 ENSDART00000148995
slc25a44a
solute carrier family 25, member 44 a
chr17_+_51940768 4.04 ENSDART00000053422
ttll5
tubulin tyrosine ligase-like family, member 5
chr15_+_44184367 3.98 ENSDART00000162918
ENSDART00000110060
zgc:165514
zgc:165514
chr7_-_37895771 3.87 ENSDART00000084282
papd5
PAP associated domain containing 5
chr8_+_7875110 3.80 ENSDART00000167423
ENSDART00000160267
ENSDART00000180490
mbd1a
methyl-CpG binding domain protein 1a
chr13_-_24826607 3.79 ENSDART00000087786
ENSDART00000186951
slka
STE20-like kinase a
chr22_-_38274188 3.76 ENSDART00000139420
ENSDART00000015117
elavl2
ELAV like neuron-specific RNA binding protein 2
chr5_-_18961694 3.75 ENSDART00000142531
ENSDART00000090521
ankle2
ankyrin repeat and LEM domain containing 2
chr25_-_37121335 3.71 ENSDART00000017805
nfat5a
nuclear factor of activated T cells 5a
chr1_+_51615672 3.66 ENSDART00000165117
zgc:165656
zgc:165656
chr22_+_21549419 3.63 ENSDART00000139411
plpp2b
phospholipid phosphatase 2b
chr19_-_18127808 3.62 ENSDART00000108627
snx10a
sorting nexin 10a
chr8_+_50150834 3.61 ENSDART00000056074
entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr19_-_18127629 3.58 ENSDART00000187722
snx10a
sorting nexin 10a
chr8_-_22326744 3.53 ENSDART00000137645
cep104
centrosomal protein 104
chr8_+_23861461 3.52 ENSDART00000037109
srpk1a
SRSF protein kinase 1a
chr5_+_19933356 3.47 ENSDART00000088819
ankrd13a
ankyrin repeat domain 13A
chr7_+_46020508 3.45 ENSDART00000170294
ccne1
cyclin E1
chr18_-_7097403 3.43 ENSDART00000003748
cfap161
cilia and flagella associated protein 161
chr1_+_51191049 3.43 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
btbd3a
BTB (POZ) domain containing 3a
chr11_+_27134116 3.42 ENSDART00000129736
hdac11
histone deacetylase 11
chr17_-_868004 3.41 ENSDART00000112803
wdr20a
WD repeat domain 20a
chr14_-_46198373 3.40 ENSDART00000031640
ENSDART00000132966
zgc:113425
zgc:113425
chr10_+_29855213 3.38 ENSDART00000099992
ENSDART00000127723
ENSDART00000125475
jhy
junctional cadherin complex regulator
chr13_-_15793585 3.38 ENSDART00000145914
ENSDART00000010286
bag5
BCL2 associated athanogene 5
chr15_+_44250335 3.37 ENSDART00000186162
ENSDART00000193503
ENSDART00000180275
zgc:162962
zgc:162962
chr14_-_763744 3.37 ENSDART00000165856
trim35-27
tripartite motif containing 35-27
chr21_+_3928947 3.34 ENSDART00000149777
setx
senataxin
chr25_+_2776511 3.31 ENSDART00000115280
neo1b
neogenin 1b
chr5_+_29652513 3.29 ENSDART00000035400
tsc1a
TSC complex subunit 1a
chr25_-_20666754 3.29 ENSDART00000158418
csk
C-terminal Src kinase
chr19_+_28291062 3.29 ENSDART00000163382
lpcat1
lysophosphatidylcholine acyltransferase 1
chr7_+_57088920 3.27 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr19_-_4785734 3.26 ENSDART00000113088
st3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr19_+_28291376 3.21 ENSDART00000139433
ENSDART00000103855
lpcat1
lysophosphatidylcholine acyltransferase 1
chr23_+_45845423 3.20 ENSDART00000183404
lmnl3
lamin L3
chr12_-_33558727 3.19 ENSDART00000086087
mbtd1
mbt domain containing 1
chr2_-_17492486 3.19 ENSDART00000189464
kdm4ab
lysine (K)-specific demethylase 4A, genome duplicate b
chr11_+_5565082 3.19 ENSDART00000112590
ENSDART00000183207
si:ch73-40i7.5
si:ch73-40i7.5
chr19_+_4856351 3.18 ENSDART00000093402
cdk12
cyclin-dependent kinase 12
chr23_-_44723102 3.12 ENSDART00000129138
mogat3a
monoacylglycerol O-acyltransferase 3a
chr11_+_27133560 3.12 ENSDART00000158411
hdac11
histone deacetylase 11
chr10_-_40939303 3.10 ENSDART00000134295
bmp1b
bone morphogenetic protein 1b
chr12_-_33558879 3.10 ENSDART00000161167
mbtd1
mbt domain containing 1
chr19_+_30450125 3.09 ENSDART00000073704
si:ch211-215a10.4
si:ch211-215a10.4
chr22_-_4989803 3.05 ENSDART00000181359
ENSDART00000125265
ENSDART00000028634
ENSDART00000183294
cherp
calcium homeostasis endoplasmic reticulum protein
chr18_+_14645568 3.05 ENSDART00000138995
ENSDART00000147351
vps9d1
VPS9 domain containing 1
chr14_+_14806692 3.05 ENSDART00000193050
fhdc2
FH2 domain containing 2
chr2_+_30182431 3.04 ENSDART00000004903
rdh10b
retinol dehydrogenase 10b
chr14_-_899170 3.04 ENSDART00000165211
ENSDART00000031992
rgs14a
regulator of G protein signaling 14a
chr6_-_9676108 3.03 ENSDART00000169915
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr3_+_48473346 3.01 ENSDART00000166294
metrnl
meteorin, glial cell differentiation regulator-like
chr9_+_37366973 2.98 ENSDART00000016370
dirc2
disrupted in renal carcinoma 2
chr19_+_24891747 2.95 ENSDART00000132209
ENSDART00000193610
eya3
EYA transcriptional coactivator and phosphatase 3
chr23_-_26227805 2.94 ENSDART00000158082
BX927204.1

chr23_+_40410644 2.94 ENSDART00000056328
elovl4b
ELOVL fatty acid elongase 4b
chr23_-_26228077 2.93 ENSDART00000162423
BX927204.1

chr25_+_8921425 2.93 ENSDART00000128591
accs
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr6_-_12900154 2.93 ENSDART00000080408
ENSDART00000150887
ical1
islet cell autoantigen 1-like
chr16_+_25285998 2.90 ENSDART00000154112
si:dkey-29h14.10
si:dkey-29h14.10
chr19_-_7043355 2.89 ENSDART00000104845
tapbp.1
TAP binding protein (tapasin), tandem duplicate 1
chr21_+_11521163 2.88 ENSDART00000139267
zgc:114104
zgc:114104
chr21_-_18275226 2.88 ENSDART00000126672
ENSDART00000135239
brd3a
bromodomain containing 3a
chr6_-_7686594 2.86 ENSDART00000091836
ENSDART00000151697
ubn2a
ubinuclein 2a
chr21_+_38745094 2.85 ENSDART00000113316
heatr6
HEAT repeat containing 6
chr11_-_30508843 2.84 ENSDART00000101667
ENSDART00000179930
map4k3a
mitogen-activated protein kinase kinase kinase kinase 3a
chr25_+_2776865 2.82 ENSDART00000156567
neo1b
neogenin 1b
chr11_+_31236001 2.82 ENSDART00000129393
trmt1
tRNA methyltransferase 1
chr13_+_25364324 2.81 ENSDART00000187471
chuk
conserved helix-loop-helix ubiquitous kinase
chr21_-_3613702 2.81 ENSDART00000139194
dym
dymeclin
chr20_-_6131686 2.80 ENSDART00000145964
ENSDART00000086578
ENSDART00000164090
pum2
pumilio RNA-binding family member 2
chr7_+_17953589 2.79 ENSDART00000174778
ENSDART00000113120
taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr19_-_42238003 2.78 ENSDART00000151022
si:ch211-191i18.4
si:ch211-191i18.4
chr10_-_40939706 2.77 ENSDART00000059795
ENSDART00000190510
bmp1b
bone morphogenetic protein 1b
chr2_-_17492080 2.77 ENSDART00000024302
kdm4ab
lysine (K)-specific demethylase 4A, genome duplicate b
chr13_+_25364753 2.75 ENSDART00000027428
chuk
conserved helix-loop-helix ubiquitous kinase
chr1_-_53918839 2.75 ENSDART00000032552
taf5l
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr4_-_12286067 2.74 ENSDART00000022646
cnot4b
CCR4-NOT transcription complex, subunit 4b
chr12_+_2804505 2.74 ENSDART00000152193
mms19
MMS19 homolog, cytosolic iron-sulfur assembly component
chr25_-_34740627 2.74 ENSDART00000137665
frs2b
fibroblast growth factor receptor substrate 2b
chr3_+_14571813 2.73 ENSDART00000146728
ENSDART00000171731
znf653
zinc finger protein 653
chr13_-_35844961 2.73 ENSDART00000171371
map3k4
mitogen-activated protein kinase kinase kinase 4
chr16_-_32304764 2.72 ENSDART00000143859
ENSDART00000134381
mms22l
MMS22-like, DNA repair protein
chr25_-_35296165 2.72 ENSDART00000018107
fancf
Fanconi anemia, complementation group F
chr12_-_2800809 2.71 ENSDART00000152682
ENSDART00000083784
ubtd1b
ubiquitin domain containing 1b
chr5_+_431994 2.71 ENSDART00000181692
ENSDART00000170350
thap1
THAP domain containing, apoptosis associated protein 1
chr25_-_35101673 2.70 ENSDART00000140864
zgc:162611
zgc:162611
chr7_+_39738505 2.69 ENSDART00000004365
tada2b
transcriptional adaptor 2B
chr23_-_31810222 2.69 ENSDART00000134319
ENSDART00000139076
hbs1l
HBS1-like translational GTPase
chr25_-_37186894 2.68 ENSDART00000191647
ENSDART00000182095
tdrd12
tudor domain containing 12
chr21_-_11327830 2.68 ENSDART00000122331
rtkn2b
rhotekin 2b
chr2_-_58075414 2.67 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr22_-_547748 2.67 ENSDART00000037455
ENSDART00000140101
ccnd3
cyclin D3
chr23_-_27442544 2.67 ENSDART00000019521
dip2ba
disco-interacting protein 2 homolog Ba
chr9_+_25096500 2.66 ENSDART00000135074
ENSDART00000180436
ENSDART00000108629
lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr17_+_33415319 2.65 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
snap23.1
synaptosomal-associated protein 23.1
chr14_+_46118834 2.65 ENSDART00000124417
ENSDART00000017785
naa15a
N(alpha)-acetyltransferase 15, NatA auxiliary subunit a
chr1_-_39983730 2.62 ENSDART00000160066
ing2
inhibitor of growth family, member 2
chr1_-_50247 2.62 ENSDART00000168428
ildr1a
immunoglobulin-like domain containing receptor 1a
chr5_+_36666715 2.61 ENSDART00000097686
zgc:153990
zgc:153990
chr20_-_14114078 2.61 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr12_+_36428052 2.60 ENSDART00000131300
unk
unkempt family zinc finger
chr5_+_29652198 2.59 ENSDART00000184083
tsc1a
TSC complex subunit 1a
chr2_+_21356242 2.59 ENSDART00000145670
ENSDART00000146600
ctdsplb
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr24_+_39129316 2.58 ENSDART00000155346
tbc1d24
TBC1 domain family, member 24
chr4_-_5691257 2.57 ENSDART00000110497
tmem63a
transmembrane protein 63A
chr21_+_6114709 2.56 ENSDART00000065858
fpgs
folylpolyglutamate synthase
chr23_+_43668756 2.56 ENSDART00000112598
otud4
OTU deubiquitinase 4
chr20_+_38543542 2.55 ENSDART00000145254
gtf3c2
general transcription factor IIIC, polypeptide 2, beta
chr25_+_32496877 2.54 ENSDART00000132698
ctdspl2a
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr25_+_15938880 2.54 ENSDART00000089035
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr24_-_25166416 2.53 ENSDART00000111552
ENSDART00000169495
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr13_+_39277178 2.52 ENSDART00000113259
si:dkey-85a20.4
si:dkey-85a20.4
chr1_+_19094548 2.52 ENSDART00000114514
ptpn9b
protein tyrosine phosphatase, non-receptor type 9, b
chr13_+_49727333 2.52 ENSDART00000168799
ENSDART00000037559
ggps1
geranylgeranyl diphosphate synthase 1
chr21_-_4764120 2.51 ENSDART00000129355
ENSDART00000102643
camsap1a
calmodulin regulated spectrin-associated protein 1a
chr21_+_6114305 2.49 ENSDART00000141607
fpgs
folylpolyglutamate synthase
chr23_+_12160900 2.49 ENSDART00000136046
ppp1r3da
protein phosphatase 1, regulatory subunit 3Da
chr18_+_17600570 2.47 ENSDART00000175258
ENSDART00000151850
ENSDART00000151934
herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr5_+_71924175 2.47 ENSDART00000115182
ENSDART00000170215
nup214
nucleoporin 214
chr23_+_43770149 2.46 ENSDART00000024313
rnf150b
ring finger protein 150b
chr8_-_34427364 2.45 ENSDART00000112854
ENSDART00000161282
ENSDART00000113230
gapvd1
GTPase activating protein and VPS9 domains 1
chr8_-_51954562 2.44 ENSDART00000132527
ENSDART00000057315
cep78
centrosomal protein 78
chr6_-_24392909 2.44 ENSDART00000171042
ENSDART00000168355
brdt
bromodomain, testis-specific
chr1_+_47165842 2.43 ENSDART00000053152
ENSDART00000167051
cbr1
carbonyl reductase 1
chr15_-_16384184 2.43 ENSDART00000154504
fam222bb
family with sequence similarity 222, member Bb
chr21_-_11367271 2.43 ENSDART00000151000
ENSDART00000151465
zgc:162472
zgc:162472
chr19_-_42238440 2.42 ENSDART00000132591
si:ch211-191i18.4
si:ch211-191i18.4
chr13_-_48161568 2.42 ENSDART00000109469
ENSDART00000188052
ENSDART00000193446
ENSDART00000189509
ENSDART00000184810
golga4
golgin A4
chr2_+_21356500 2.41 ENSDART00000171397
ctdsplb
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr5_+_23913585 2.40 ENSDART00000015401
ercc6l
excision repair cross-complementation group 6-like
chr6_-_18228358 2.39 ENSDART00000167937
p4hb
prolyl 4-hydroxylase, beta polypeptide
chr10_-_17550931 2.38 ENSDART00000145077
ska1
spindle and kinetochore associated complex subunit 1
chr4_+_2482046 2.38 ENSDART00000103371
zdhhc17
zinc finger, DHHC-type containing 17
chr19_-_47832853 2.38 ENSDART00000170988
ago4
argonaute RISC catalytic component 4
chr2_-_57076687 2.37 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr13_-_9367647 2.37 ENSDART00000083362
ENSDART00000144146
si:dkey-33c12.4
si:dkey-33c12.4
chr25_-_35101396 2.36 ENSDART00000138865
zgc:162611
zgc:162611
chr15_+_38221038 2.36 ENSDART00000188149
stim1a
stromal interaction molecule 1a
chr10_-_3394256 2.35 ENSDART00000158315
ENSDART00000111241
naa25
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chr21_+_18274825 2.35 ENSDART00000144322
ENSDART00000147768
wdr5
WD repeat domain 5
chr21_+_3897680 2.35 ENSDART00000170653
dolpp1
dolichyldiphosphatase 1
chr21_-_34032650 2.33 ENSDART00000138575
ENSDART00000047515
rnf145b
ring finger protein 145b
chr21_-_1644414 2.32 ENSDART00000105736
ENSDART00000124904
zgc:152948
zgc:152948
chr15_+_24549054 2.31 ENSDART00000155900
phf12b
PHD finger protein 12b
chr5_-_11809404 2.31 ENSDART00000132564
nf2a
neurofibromin 2a (merlin)
chr8_-_45939691 2.29 ENSDART00000040066
ENSDART00000132297
adam9
ADAM metallopeptidase domain 9
chr18_+_3579829 2.29 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr20_-_53624645 2.28 ENSDART00000083427
ENSDART00000152920
slc25a29
solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
chr5_-_2676783 2.27 ENSDART00000159661
CABZ01072548.1

chr25_-_20666328 2.27 ENSDART00000098076
csk
C-terminal Src kinase
chr23_+_10805188 2.27 ENSDART00000035693
ppp4r2a
protein phosphatase 4, regulatory subunit 2a
chr21_-_14878220 2.27 ENSDART00000131237
ulk1b
unc-51 like autophagy activating kinase 1
chr24_-_24983047 2.26 ENSDART00000066631
slc51a
solute carrier family 51, alpha subunit
chr1_+_15258641 2.26 ENSDART00000033018
pi4k2b
phosphatidylinositol 4-kinase type 2 beta
chr3_-_40837218 2.26 ENSDART00000134026
wipi2
WD repeat domain, phosphoinositide interacting 2
chr11_-_20988238 2.26 ENSDART00000155238
taf4a
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_+_47862636 2.26 ENSDART00000139824
rasa1a
RAS p21 protein activator (GTPase activating protein) 1a
chr11_+_2763168 2.25 ENSDART00000042972
srpk1b
SRSF protein kinase 1b
chr12_+_22560067 2.25 ENSDART00000172066
polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr19_-_7070691 2.23 ENSDART00000168755
tapbp.2
TAP binding protein (tapasin), tandem duplicate 2
chr16_-_26528140 2.22 ENSDART00000134448
ENSDART00000147062
l3mbtl1b
l(3)mbt-like 1b (Drosophila)
chr22_+_8536838 2.21 ENSDART00000132998
si:ch73-27e22.7
si:ch73-27e22.7
chr13_-_49144799 2.20 ENSDART00000030939
ENSDART00000148922
disc1
disrupted in schizophrenia 1
chr6_-_9695294 2.18 ENSDART00000162728
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr20_+_1121458 2.16 ENSDART00000064472
pnrc1
proline-rich nuclear receptor coactivator 1
chr10_+_37268854 2.16 ENSDART00000131897
nf1b
neurofibromin 1b
chr2_+_2818645 2.16 ENSDART00000163587
rock1
Rho-associated, coiled-coil containing protein kinase 1
chr2_+_30489846 2.15 ENSDART00000145732
march6
membrane-associated ring finger (C3HC4) 6
chr5_-_64454459 2.15 ENSDART00000172321
ENSDART00000168030
brd3b
bromodomain containing 3b
chr17_+_33415542 2.15 ENSDART00000183169
snap23.1
synaptosomal-associated protein 23.1
chr9_+_34380299 2.15 ENSDART00000131705
lamp1
lysosomal-associated membrane protein 1
chr9_+_45605410 2.14 ENSDART00000136444
ENSDART00000007189
ENSDART00000158713
ENSDART00000182671
traf3ip1
TNF receptor-associated factor 3 interacting protein 1
chr19_+_20787179 2.14 ENSDART00000193204
adnp2b
ADNP homeobox 2b
chr13_-_34862452 2.14 ENSDART00000134573
ENSDART00000047552
sptlc3
serine palmitoyltransferase, long chain base subunit 3
chr15_-_30984557 2.13 ENSDART00000080328
nf1a
neurofibromin 1a
chr24_-_25166720 2.13 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr12_+_18906407 2.12 ENSDART00000105854
josd1
Josephin domain containing 1
chr11_+_2649891 2.10 ENSDART00000093052
si:ch211-160o17.4
si:ch211-160o17.4
chr25_-_752158 2.09 ENSDART00000130610
tmem117
transmembrane protein 117

Network of associatons between targets according to the STRING database.

First level regulatory network of nrf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 13.0 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
1.5 4.5 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
1.4 7.2 GO:0070986 left/right axis specification(GO:0070986)
1.3 5.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
1.2 3.6 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
1.1 5.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
1.1 5.6 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
1.0 9.9 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.9 2.8 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.9 5.5 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.9 2.7 GO:2000402 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.8 2.5 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.8 5.4 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.7 5.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.7 3.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.7 2.0 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.6 5.2 GO:0008343 adult feeding behavior(GO:0008343)
0.6 4.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.6 5.4 GO:2000758 positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.6 1.8 GO:0070417 cellular response to cold(GO:0070417)
0.6 3.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.6 2.3 GO:0006844 acyl carnitine transport(GO:0006844)
0.6 2.2 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.6 1.7 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.6 2.2 GO:0021755 eurydendroid cell differentiation(GO:0021755)
0.5 2.7 GO:0090342 regulation of cell aging(GO:0090342)
0.5 1.6 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.5 2.0 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.5 1.8 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.5 1.4 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.5 3.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.4 5.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.4 2.1 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.4 5.9 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.4 3.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.4 1.6 GO:0070285 pigment cell development(GO:0070285)
0.4 2.0 GO:0071763 nuclear membrane organization(GO:0071763)
0.4 2.4 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.4 2.0 GO:0061438 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.4 1.9 GO:0010586 miRNA metabolic process(GO:0010586)
0.4 1.8 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.4 1.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.3 5.8 GO:0034629 cellular protein complex localization(GO:0034629)
0.3 2.7 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.3 1.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.3 1.9 GO:0006013 mannose metabolic process(GO:0006013)
0.3 1.5 GO:0010939 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.3 4.5 GO:0009086 methionine biosynthetic process(GO:0009086)
0.3 1.2 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.3 2.0 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.3 2.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.3 0.9 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.3 0.8 GO:0000212 meiotic spindle organization(GO:0000212)
0.3 5.3 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.3 2.9 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.3 1.3 GO:0045056 transcytosis(GO:0045056)
0.3 0.8 GO:0051170 nuclear import(GO:0051170)
0.2 3.0 GO:0042572 retinoic acid biosynthetic process(GO:0002138) retinol metabolic process(GO:0042572)
0.2 4.4 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.2 3.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 6.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.2 1.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 4.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 4.0 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.2 5.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.2 2.1 GO:0030104 water homeostasis(GO:0030104)
0.2 4.3 GO:0031297 replication fork processing(GO:0031297)
0.2 3.7 GO:0002574 thrombocyte differentiation(GO:0002574)
0.2 2.8 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.2 2.0 GO:0070977 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.2 1.2 GO:0051013 microtubule severing(GO:0051013)
0.2 2.2 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.2 1.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 2.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.2 1.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 1.3 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.2 0.5 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 2.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.2 5.6 GO:0030488 tRNA methylation(GO:0030488)
0.2 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 3.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 0.8 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.2 1.0 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.2 2.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 3.0 GO:0008354 germ cell migration(GO:0008354)
0.2 1.3 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 0.5 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.2 2.4 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 1.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 1.4 GO:0006465 signal peptide processing(GO:0006465)
0.1 1.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 2.3 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 2.5 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 4.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.4 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 1.8 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 1.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 1.9 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 0.7 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 6.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 1.3 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.1 2.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.7 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.1 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.1 3.0 GO:0009408 response to heat(GO:0009408)
0.1 2.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 2.8 GO:0016180 snRNA processing(GO:0016180)
0.1 0.3 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.1 1.3 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1 5.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 2.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 3.4 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 1.5 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 2.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.6 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1 0.8 GO:0016075 rRNA catabolic process(GO:0016075)
0.1 2.0 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 1.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 2.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 1.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.9 GO:0045444 fat cell differentiation(GO:0045444)
0.1 3.1 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 1.4 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 2.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 1.6 GO:0048264 determination of ventral identity(GO:0048264)
0.1 1.9 GO:0042476 odontogenesis(GO:0042476)
0.1 2.5 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 0.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 1.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.3 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.1 0.9 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.1 1.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 7.4 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 3.0 GO:0048634 regulation of muscle organ development(GO:0048634)
0.1 3.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 2.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 1.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.2 GO:0007032 endosome organization(GO:0007032)
0.1 1.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 1.6 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 1.9 GO:0008643 carbohydrate transport(GO:0008643)
0.1 1.4 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 2.1 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.6 GO:0007589 body fluid secretion(GO:0007589)
0.1 4.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.4 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.1 0.5 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 5.2 GO:0042254 ribosome biogenesis(GO:0042254)
0.1 8.7 GO:0006338 chromatin remodeling(GO:0006338)
0.1 1.5 GO:0016925 protein sumoylation(GO:0016925)
0.1 1.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 2.7 GO:0031047 gene silencing by RNA(GO:0031047)
0.1 1.2 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 0.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.4 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 1.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 4.1 GO:0036503 ERAD pathway(GO:0036503)
0.0 1.0 GO:0021986 habenula development(GO:0021986)
0.0 4.1 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.4 GO:0006901 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.9 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.4 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 3.8 GO:0008033 tRNA processing(GO:0008033)
0.0 1.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 2.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.0 GO:0050821 protein stabilization(GO:0050821)
0.0 8.6 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.2 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 1.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.0 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:1901910 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 3.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.5 GO:0060030 dorsal convergence(GO:0060030)
0.0 2.7 GO:0007030 Golgi organization(GO:0007030)
0.0 0.4 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 2.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 2.0 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 2.1 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.2 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331) regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.0 1.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.9 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 1.1 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 1.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.7 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.4 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.5 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.0 10.1 GO:0006396 RNA processing(GO:0006396)
0.0 0.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 5.2 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.7 GO:0038127 ERBB signaling pathway(GO:0038127)
0.0 0.1 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.7 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.4 GO:0001878 response to yeast(GO:0001878)
0.0 0.4 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.8 GO:0045089 positive regulation of innate immune response(GO:0045089)
0.0 0.7 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.0 0.4 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.6 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 1.0 GO:0006665 sphingolipid metabolic process(GO:0006665)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 9.9 GO:0071546 pi-body(GO:0071546)
1.2 5.9 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.1 6.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
1.1 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
1.0 3.1 GO:0010369 chromocenter(GO:0010369)
0.9 5.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.9 2.7 GO:0097361 CIA complex(GO:0097361)
0.8 5.5 GO:0030914 STAGA complex(GO:0030914)
0.8 5.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.8 2.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.7 4.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.6 3.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.6 2.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.6 1.7 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.5 3.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.5 2.7 GO:0031415 NatA complex(GO:0031415)
0.5 5.3 GO:0036449 microtubule minus-end(GO:0036449)
0.5 2.4 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.4 1.3 GO:0055087 Ski complex(GO:0055087)
0.4 1.2 GO:0008352 katanin complex(GO:0008352)
0.4 7.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 4.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 3.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.4 1.8 GO:1990071 TRAPPII protein complex(GO:1990071)
0.3 1.4 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 2.4 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.3 2.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.3 0.9 GO:0072380 TRC complex(GO:0072380)
0.3 0.8 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.3 2.5 GO:0089701 U2AF(GO:0089701)
0.3 1.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 2.7 GO:0035101 FACT complex(GO:0035101)
0.2 2.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 5.2 GO:0045180 basal cortex(GO:0045180)
0.2 2.7 GO:0070461 SAGA-type complex(GO:0070461)
0.2 4.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 2.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 3.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 3.5 GO:0016363 nuclear matrix(GO:0016363)
0.2 2.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 1.4 GO:0032797 SMN complex(GO:0032797)
0.2 3.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.2 GO:0070847 core mediator complex(GO:0070847)
0.2 1.2 GO:0071818 BAT3 complex(GO:0071818)
0.2 1.7 GO:0030904 retromer complex(GO:0030904)
0.2 1.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 3.3 GO:0070822 Sin3-type complex(GO:0070822)
0.1 7.8 GO:0005811 lipid particle(GO:0005811)
0.1 2.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.1 GO:0072487 MSL complex(GO:0072487)
0.1 1.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 2.8 GO:0032039 integrator complex(GO:0032039)
0.1 0.4 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.5 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 2.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 2.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 6.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.6 GO:0005686 U2 snRNP(GO:0005686)
0.1 2.0 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 3.0 GO:0000145 exocyst(GO:0000145)
0.1 4.0 GO:0016605 PML body(GO:0016605)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.3 GO:0017119 Golgi transport complex(GO:0017119)
0.1 14.6 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 3.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 2.3 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 9.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 3.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.0 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.1 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 3.6 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.1 1.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.8 GO:0030008 TRAPP complex(GO:0030008)
0.1 4.2 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 2.7 GO:0043204 perikaryon(GO:0043204)
0.1 2.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.4 GO:0070652 HAUS complex(GO:0070652)
0.1 1.8 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.5 GO:0035060 brahma complex(GO:0035060)
0.1 0.3 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 1.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 1.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 6.8 GO:0016604 nuclear body(GO:0016604)
0.0 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 11.9 GO:0005813 centrosome(GO:0005813)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 2.5 GO:0031514 motile cilium(GO:0031514)
0.0 1.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 5.7 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.1 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 3.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 1.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 2.1 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 7.7 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.5 GO:0005657 replication fork(GO:0005657)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 13.0 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.4 5.6 GO:0008384 IkappaB kinase activity(GO:0008384)
1.3 6.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
1.2 9.9 GO:0034584 piRNA binding(GO:0034584)
1.1 3.3 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.9 2.6 GO:1990715 mRNA CDS binding(GO:1990715)
0.8 2.4 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.7 2.8 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.6 3.1 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.6 2.3 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.6 4.5 GO:0031419 cobalamin binding(GO:0031419)
0.6 2.2 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.6 5.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.5 3.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.5 2.0 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.5 6.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5 3.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4 1.8 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.4 1.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.4 5.3 GO:0030507 spectrin binding(GO:0030507)
0.4 2.4 GO:0015616 DNA translocase activity(GO:0015616)
0.4 5.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 3.8 GO:0035198 miRNA binding(GO:0035198)
0.4 4.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4 1.1 GO:0036310 annealing helicase activity(GO:0036310)
0.3 10.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.3 4.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 3.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 5.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.3 1.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.9 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 3.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 3.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.3 10.9 GO:0035064 methylated histone binding(GO:0035064)
0.3 2.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.3 3.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 1.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.3 4.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.3 0.8 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.3 2.7 GO:0030332 cyclin binding(GO:0030332)
0.3 2.2 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.3 5.2 GO:0030515 snoRNA binding(GO:0030515)
0.3 0.8 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.3 5.1 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.3 2.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 2.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 1.0 GO:0033149 FFAT motif binding(GO:0033149)
0.2 1.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 3.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.8 GO:0045309 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.2 4.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 3.6 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 1.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 1.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 1.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 1.7 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.2 2.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 2.5 GO:2001069 glycogen binding(GO:2001069)
0.2 2.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 4.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.6 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 1.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.7 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 3.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 3.5 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.9 GO:0005123 death receptor binding(GO:0005123) receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.1 1.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 5.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 3.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 2.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.9 GO:0004985 opioid receptor activity(GO:0004985)
0.1 1.9 GO:0015149 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 2.5 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 1.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 7.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 2.0 GO:0019894 kinesin binding(GO:0019894)
0.1 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 2.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 1.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 13.9 GO:0042393 histone binding(GO:0042393)
0.1 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.6 GO:0070411 I-SMAD binding(GO:0070411)
0.1 2.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 2.0 GO:0005112 Notch binding(GO:0005112)
0.1 1.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.7 GO:0008143 poly(A) binding(GO:0008143)
0.1 2.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 4.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.2 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 5.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 3.8 GO:0031072 heat shock protein binding(GO:0031072)
0.1 1.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 10.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.2 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 6.9 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 0.9 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 4.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 11.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 12.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 0.5 GO:0070628 proteasome binding(GO:0070628)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 2.9 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 1.4 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 3.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.2 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 1.3 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 3.6 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.7 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 2.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 9.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 2.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.5 GO:0009975 cyclase activity(GO:0009975)
0.0 3.4 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.4 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 5.2 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 13.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 2.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 4.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 3.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 6.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.4 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.5 GO:0008173 RNA methyltransferase activity(GO:0008173)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 2.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 5.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 2.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 5.5 PID BARD1 PATHWAY BARD1 signaling events
0.1 2.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 5.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 2.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.8 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.3 PID ARF 3PATHWAY Arf1 pathway
0.1 1.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 2.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 0.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 1.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.3 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 13.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
1.1 5.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.8 6.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.6 5.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.4 3.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 4.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 2.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 4.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 3.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 2.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 6.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 7.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.8 REACTOME KINESINS Genes involved in Kinesins
0.1 2.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 4.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 1.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 3.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 2.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 3.1 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.5 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.8 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.1 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response