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PRJNA195909:zebrafish embryo and larva development

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Results for otx2b

Z-value: 2.20

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Transcription factors associated with otx2b

Gene Symbol Gene ID Gene Info
otx2b
ENSDARG00000011235 orthodenticle homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx2bdr11_v1_chr17_-_44249720_442497200.781.3e-02Click!

Activity profile of otx2b motif

Sorted Z-values of otx2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_26144765 10.88 ENSDART00000146267
ENSDART00000043932
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr15_+_32727848 5.32 ENSDART00000161361
postnb
periostin, osteoblast specific factor b
chr5_-_28625515 4.26 ENSDART00000190782
ENSDART00000179736
ENSDART00000131729
tnc
tenascin C
chr23_+_36063599 3.74 ENSDART00000103147
hoxc12a
homeobox C12a
chr14_-_4273396 3.54 ENSDART00000127318
frmpd1b
FERM and PDZ domain containing 1b
chr8_-_54077740 3.45 ENSDART00000027000
rho
rhodopsin
chr22_+_5103349 3.42 ENSDART00000083474
atcaya
ataxia, cerebellar, Cayman type a
chr14_+_46313135 3.41 ENSDART00000172902
cryba1l1
crystallin, beta A1, like 1
chr7_-_13882988 3.34 ENSDART00000169828
rlbp1a
retinaldehyde binding protein 1a
chr14_-_36378494 3.33 ENSDART00000058503
gpm6aa
glycoprotein M6Aa
chr15_+_32711172 3.25 ENSDART00000163936
ENSDART00000168135
postnb
periostin, osteoblast specific factor b
chr15_+_33070939 3.17 ENSDART00000164928
mab21l1
mab-21-like 1
chr23_-_6641223 3.14 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr1_+_17593392 2.95 ENSDART00000078889
helt
helt bHLH transcription factor
chr16_+_32059785 2.86 ENSDART00000134459
si:dkey-40m6.8
si:dkey-40m6.8
chr5_-_28606916 2.67 ENSDART00000026107
ENSDART00000137717
tnc
tenascin C
chr7_-_41489822 2.60 ENSDART00000006724
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr7_+_67467702 2.51 ENSDART00000168460
ENSDART00000170322
rpl13
ribosomal protein L13
chr8_+_6954984 2.51 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr13_-_39947335 2.16 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5
chr3_+_23703704 2.13 ENSDART00000024256
hoxb6a
homeobox B6a
chr15_-_2652640 2.11 ENSDART00000146094
cldnf
claudin f
chr9_+_26103814 2.10 ENSDART00000026011
efnb2a
ephrin-B2a
chr16_+_20926673 2.08 ENSDART00000009827
hoxa2b
homeobox A2b
chr3_+_1492174 2.07 ENSDART00000112979
sox10
SRY (sex determining region Y)-box 10
chr11_+_2172335 2.00 ENSDART00000170593
hoxc12b
homeobox C12b
chr7_-_41489997 1.97 ENSDART00000174300
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr10_+_32104305 1.93 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr7_+_71335815 1.91 ENSDART00000102756
sod3a
superoxide dismutase 3, extracellular a
chr6_-_28980756 1.89 ENSDART00000014661
glmnb
glomulin, FKBP associated protein b
chr9_+_7724152 1.87 ENSDART00000061716
mnx2a
motor neuron and pancreas homeobox 2a
chr19_-_8880688 1.86 ENSDART00000039629
celf3a
cugbp, Elav-like family member 3a
chr21_-_20341836 1.84 ENSDART00000176689
rbp4l
retinol binding protein 4, like
chr3_-_28828242 1.78 ENSDART00000151445
si:ch211-76l23.4
si:ch211-76l23.4
chr16_+_42830152 1.71 ENSDART00000159730
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr8_-_22964486 1.69 ENSDART00000112381
emilin3a
elastin microfibril interfacer 3a
chr20_+_53441935 1.66 ENSDART00000175214
apobb.2
apolipoprotein Bb, tandem duplicate 2
chr6_-_20875111 1.65 ENSDART00000115118
ENSDART00000159916
tns1a
tensin 1a
chr16_-_33059246 1.65 ENSDART00000171718
ENSDART00000168305
ENSDART00000166401
snap91
synaptosomal-associated protein 91
chr11_-_15090564 1.63 ENSDART00000162079
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr3_+_23743139 1.59 ENSDART00000187409
hoxb3a
homeobox B3a
chr10_+_4095917 1.58 ENSDART00000114533
mn1a
meningioma 1a
chr3_+_23742868 1.54 ENSDART00000153512
hoxb3a
homeobox B3a
chr21_-_20342096 1.51 ENSDART00000065659
rbp4l
retinol binding protein 4, like
chr17_-_12389259 1.51 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr5_+_22510639 1.48 ENSDART00000080919
rpl36a
ribosomal protein L36A
chr18_-_22753637 1.48 ENSDART00000181589
ENSDART00000009912
hsf4
heat shock transcription factor 4
chr16_+_42829735 1.47 ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr5_-_14344647 1.47 ENSDART00000188456
tet3
tet methylcytosine dioxygenase 3
chr3_+_49521106 1.45 ENSDART00000162799
crb3a
crumbs homolog 3a
chr1_-_20273227 1.43 ENSDART00000146084
ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr17_+_18117029 1.40 ENSDART00000154646
ENSDART00000179739
bcl11ba
B cell CLL/lymphoma 11Ba
chr6_-_39270851 1.39 ENSDART00000148839
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr21_-_40782393 1.38 ENSDART00000075808
apbb3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr3_+_34919810 1.37 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr19_+_19729506 1.36 ENSDART00000171610
hoxa13a
homeobox A13a
chr23_+_13814978 1.35 ENSDART00000090864
lmod3
leiomodin 3 (fetal)
chr12_+_15622621 1.35 ENSDART00000079784
plcd3b
phospholipase C, delta 3b
chr17_-_31058900 1.35 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
eml1
echinoderm microtubule associated protein like 1
chr7_+_30970045 1.35 ENSDART00000155974
tjp1a
tight junction protein 1a
chr13_+_1089942 1.31 ENSDART00000054322
cnrip1b
cannabinoid receptor interacting protein 1b
chr8_+_53928472 1.30 ENSDART00000063242
MMP23B
matrix metallopeptidase 23B
chr11_-_15090118 1.29 ENSDART00000171118
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr1_-_26293203 1.26 ENSDART00000180140
cxxc4
CXXC finger 4
chr17_-_51202339 1.25 ENSDART00000167117
si:ch1073-469d17.2
si:ch1073-469d17.2
chr3_+_18097700 1.25 ENSDART00000021634
wfikkn2a
info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a
chr7_-_50517023 1.24 ENSDART00000073910
adamtsl5
ADAMTS like 5
chr14_-_29799993 1.24 ENSDART00000133775
ENSDART00000005568
pdlim3b
PDZ and LIM domain 3b
chr22_+_20427170 1.22 ENSDART00000136744
foxq2
forkhead box Q2
chr12_-_10275320 1.20 ENSDART00000170078
mpp2b
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr2_-_4797512 1.18 ENSDART00000160765
tnk2b
tyrosine kinase, non-receptor, 2b
chr10_-_7988396 1.17 ENSDART00000141445
ENSDART00000024282
ewsr1a
EWS RNA-binding protein 1a
chr1_+_55080797 1.15 ENSDART00000077390
lgalsla
lectin, galactoside-binding-like a
chr22_-_910926 1.13 ENSDART00000180075
FP016205.1

chr5_+_11407504 1.11 ENSDART00000186723
ENSDART00000018047
zgc:112294
zgc:112294
chr25_+_19041329 1.10 ENSDART00000153467
lrtm2b
leucine-rich repeats and transmembrane domains 2b
chr7_-_35516251 1.10 ENSDART00000045628
irx6a
iroquois homeobox 6a
chr15_-_18574716 1.08 ENSDART00000142010
ENSDART00000019006
ncam1b
neural cell adhesion molecule 1b
chr1_-_45177373 1.06 ENSDART00000143142
ENSDART00000034549
zgc:111983
zgc:111983
chr8_+_23142946 1.06 ENSDART00000152933
si:ch211-196c10.13
si:ch211-196c10.13
chr4_-_9173552 1.05 ENSDART00000042963
chst11
carbohydrate (chondroitin 4) sulfotransferase 11
chr14_+_32839535 1.04 ENSDART00000168975
arr3b
arrestin 3b, retinal (X-arrestin)
chr15_-_23467750 1.04 ENSDART00000148804
pdzd3a
PDZ domain containing 3a
chr25_+_19753890 1.01 ENSDART00000190268
ENSDART00000128852
celsr1b
cadherin EGF LAG seven-pass G-type receptor 1b
chr8_-_22965214 1.01 ENSDART00000148178
emilin3a
elastin microfibril interfacer 3a
chr21_+_10739846 1.00 ENSDART00000084011
cplx4a
complexin 4a
chr23_-_28294763 0.99 ENSDART00000139537
znf385a
zinc finger protein 385A
chr17_+_16564921 0.99 ENSDART00000151904
foxn3
forkhead box N3
chr14_-_8080416 0.99 ENSDART00000045109
zgc:92242
zgc:92242
chr25_-_18913336 0.99 ENSDART00000171010
parietopsin
parietopsin
chr11_-_4235811 0.98 ENSDART00000121716
si:ch211-236d3.4
si:ch211-236d3.4
chr12_+_11080776 0.98 ENSDART00000079336
raraa
retinoic acid receptor, alpha a
chr18_+_49969568 0.97 ENSDART00000126916
mob2b
MOB kinase activator 2b
chr15_+_42599501 0.96 ENSDART00000177646
grik1b
glutamate receptor, ionotropic, kainate 1b
chr2_-_1569250 0.96 ENSDART00000167202
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr10_-_21054059 0.95 ENSDART00000139733
pcdh1a
protocadherin 1a
chr7_+_20471315 0.93 ENSDART00000173714
si:dkey-19b23.13
si:dkey-19b23.13
chr20_-_9963713 0.92 ENSDART00000104234
gjd2b
gap junction protein delta 2b
chr14_-_30587814 0.92 ENSDART00000144912
ENSDART00000149714
tmem265
transmembrane protein 265
chr6_+_36795225 0.91 ENSDART00000171504
si:ch73-29l19.1
si:ch73-29l19.1
chr15_+_37559570 0.90 ENSDART00000085522
hspb6
heat shock protein, alpha-crystallin-related, b6
chr9_-_18568927 0.89 ENSDART00000084668
enox1
ecto-NOX disulfide-thiol exchanger 1
chr12_+_39685485 0.89 ENSDART00000163403
LO017650.1

chr7_+_57866292 0.88 ENSDART00000138757
camk2d1
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr8_+_14381272 0.87 ENSDART00000057642
acbd6
acyl-CoA binding domain containing 6
chr21_+_32338897 0.84 ENSDART00000110137
si:ch211-247j9.1
si:ch211-247j9.1
chr17_-_20979077 0.82 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr1_-_39909985 0.81 ENSDART00000181673
stox2a
storkhead box 2a
chr3_-_28665291 0.81 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr9_-_8454060 0.80 ENSDART00000110158
irs2b
insulin receptor substrate 2b
chr13_-_47800342 0.79 ENSDART00000121817
fbln7
fibulin 7
chr5_-_14390445 0.78 ENSDART00000026120
ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr7_-_18656069 0.77 ENSDART00000021559
coro1b
coronin, actin binding protein, 1B
chr22_+_16446052 0.77 ENSDART00000142454
si:dkey-121a11.3
si:dkey-121a11.3
chr14_+_909769 0.76 ENSDART00000021346
ENSDART00000172777
arl3l2
ADP-ribosylation factor-like 3, like 2
chr23_-_24394719 0.74 ENSDART00000044918
epha2b
eph receptor A2 b
chr5_+_43072951 0.73 ENSDART00000193905
ENSDART00000026020
wdr54
WD repeat domain 54
chr15_-_15469079 0.71 ENSDART00000132637
ENSDART00000004220
rab34a
RAB34, member RAS oncogene family a
chr7_-_49594995 0.71 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr1_-_17650223 0.70 ENSDART00000043484
si:dkey-256e7.5
si:dkey-256e7.5
chr6_+_32415132 0.69 ENSDART00000155790
kank4
KN motif and ankyrin repeat domains 4
chr9_+_24095677 0.69 ENSDART00000150443
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr9_-_19161982 0.68 ENSDART00000081878
pou1f1
POU class 1 homeobox 1
chr11_-_27702778 0.67 ENSDART00000045942
ENSDART00000125352
phf2
PHD finger protein 2
chr16_+_24684107 0.65 ENSDART00000183920
ywhabl
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
chr15_+_29116063 0.65 ENSDART00000016112
ENSDART00000153609
ENSDART00000155630
capns1b
calpain, small subunit 1 b
chr10_-_36738619 0.64 ENSDART00000093000
ENSDART00000157179
PLEKHB1
si:ch211-176g13.7
chr14_+_5861435 0.63 ENSDART00000041279
ENSDART00000147341
tubb4b
tubulin, beta 4B class IVb
chr17_+_25289431 0.63 ENSDART00000161002
kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr23_-_35195908 0.62 ENSDART00000122429
klf15
Kruppel-like factor 15
chr7_-_12821277 0.62 ENSDART00000091584
zgc:158785
zgc:158785
chr3_+_34220194 0.62 ENSDART00000145859
slc25a23b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23b
chr5_+_34981584 0.61 ENSDART00000134795
ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr4_-_22363709 0.61 ENSDART00000037670
orc5
origin recognition complex, subunit 5
chr10_-_27199135 0.61 ENSDART00000189511
ENSDART00000180314
auts2a
autism susceptibility candidate 2a
chr24_-_1303935 0.61 ENSDART00000159212
ENSDART00000159267
ENSDART00000164904
nrp1a
neuropilin 1a
chr10_+_29260096 0.61 ENSDART00000088973
sytl2a
synaptotagmin-like 2a
chr20_-_46541834 0.60 ENSDART00000060685
ENSDART00000181720
tmed10
transmembrane p24 trafficking protein 10
chr11_-_29563437 0.60 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr6_+_9867426 0.59 ENSDART00000151749
MPP4 (1 of many)
si:ch211-222n4.6
chr23_-_27152866 0.59 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr2_+_30878864 0.58 ENSDART00000009326
oprk1
opioid receptor, kappa 1
chr11_-_3860199 0.58 ENSDART00000082420
gata2a
GATA binding protein 2a
chr8_+_27743550 0.56 ENSDART00000046004
wnt2bb
wingless-type MMTV integration site family, member 2Bb
chr1_-_58009216 0.56 ENSDART00000143829
nxnl1
nucleoredoxin like 1
chr14_-_25034142 0.54 ENSDART00000000392
pde6a
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr16_+_19536614 0.54 ENSDART00000112894
ENSDART00000079201
ENSDART00000139357
sp8b
sp8 transcription factor b
chr23_+_7505943 0.53 ENSDART00000135787
hck
HCK proto-oncogene, Src family tyrosine kinase
chr15_-_15468326 0.52 ENSDART00000161192
rab34a
RAB34, member RAS oncogene family a
chr12_+_25640480 0.52 ENSDART00000105608
prkcea
protein kinase C, epsilon a
chr7_-_52842605 0.51 ENSDART00000083002
map1aa
microtubule-associated protein 1Aa
chr1_+_33383644 0.50 ENSDART00000187194
dhrsx
dehydrogenase/reductase (SDR family) X-linked
chr20_+_35998073 0.50 ENSDART00000140457
opn5
opsin 5
chr25_-_16818195 0.49 ENSDART00000185215
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr11_+_2506516 0.49 ENSDART00000130886
ENSDART00000189767
NABP2
si:ch73-190f16.2
chr11_-_16215143 0.48 ENSDART00000027014
rab7
RAB7, member RAS oncogene family
chr2_-_48171441 0.48 ENSDART00000123040
pfkpb
phosphofructokinase, platelet b
chr15_-_24883956 0.48 ENSDART00000113199
aipl1
aryl hydrocarbon receptor interacting protein-like 1
chr17_+_36627099 0.46 ENSDART00000154104
impg1b
interphotoreceptor matrix proteoglycan 1b
chr20_-_1141722 0.46 ENSDART00000152675
gabrr1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr25_-_7925269 0.45 ENSDART00000014274
glcea
glucuronic acid epimerase a
chr3_+_15296824 0.44 ENSDART00000043801
cabp5b
calcium binding protein 5b
chr17_+_16565185 0.44 ENSDART00000136874
foxn3
forkhead box N3
chr18_+_5172848 0.43 ENSDART00000190642
CABZ01080599.1

chr1_-_16507812 0.41 ENSDART00000169081
mtmr7b
myotubularin related protein 7b
chr25_-_7925019 0.40 ENSDART00000183309
glcea
glucuronic acid epimerase a
chr15_-_38154616 0.40 ENSDART00000099392
irgq2
immunity-related GTPase family, q2
chr11_+_39672874 0.38 ENSDART00000046663
ENSDART00000157659
camta1b
calmodulin binding transcription activator 1b
chr7_+_38395197 0.37 ENSDART00000138669
cep89
centrosomal protein 89
chr24_+_24923166 0.37 ENSDART00000065288
pcyt1ba
phosphate cytidylyltransferase 1, choline, beta a
chr11_-_3860534 0.37 ENSDART00000082425
gata2a
GATA binding protein 2a
chr2_-_16217344 0.36 ENSDART00000152031
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr9_+_33357011 0.36 ENSDART00000088569
nyx
nyctalopin
chr7_+_41303572 0.36 ENSDART00000012692
rgs9bp
regulator of G protein signaling 9 binding protein
chr2_-_41861040 0.36 ENSDART00000045763
keap1a
kelch-like ECH-associated protein 1a
chr4_-_18436899 0.35 ENSDART00000141671
socs2
suppressor of cytokine signaling 2
chr13_+_12528043 0.35 ENSDART00000057761
rrh
retinal pigment epithelium-derived rhodopsin homolog
chr25_-_35996141 0.34 ENSDART00000149074
sall1b
spalt-like transcription factor 1b
chr18_+_7594012 0.34 ENSDART00000062150
zgc:77752
zgc:77752
chr20_+_6543674 0.34 ENSDART00000134204
tns3.1
tensin 3, tandem duplicate 1
chr14_-_2400668 0.33 ENSDART00000172717
ENSDART00000182882
si:ch73-233f7.1
si:ch73-233f7.1
chrM_+_15308 0.33 ENSDART00000093625
mt-cyb
cytochrome b, mitochondrial
chr2_+_28995776 0.33 ENSDART00000138733
cdh12a
cadherin 12, type 2a (N-cadherin 2)
chr2_-_48171112 0.33 ENSDART00000156258
pfkpb
phosphofructokinase, platelet b
chr24_-_31194847 0.32 ENSDART00000158808
cnn3a
calponin 3, acidic a
chr3_-_61593274 0.31 ENSDART00000154132
ENSDART00000055071
nptx2a
neuronal pentraxin 2a
chr2_+_29795833 0.31 ENSDART00000056750
si:ch211-207d6.2
si:ch211-207d6.2
chr14_-_2933185 0.30 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr12_+_41991635 0.28 ENSDART00000186161
ENSDART00000192510
TCERG1L
transcription elongation regulator 1 like
chr16_-_17188294 0.27 ENSDART00000165883
opn9
opsin 9
chr7_+_19903924 0.26 ENSDART00000159112
si:ch211-285j22.3
si:ch211-285j22.3
chr18_+_9323211 0.25 ENSDART00000166114
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr9_+_11034967 0.25 ENSDART00000152081
asic4a
acid-sensing (proton-gated) ion channel family member 4a
chr7_-_35515931 0.25 ENSDART00000193324
irx6a
iroquois homeobox 6a
chr13_-_36184701 0.23 ENSDART00000146522
map3k9
mitogen-activated protein kinase kinase kinase 9
chr11_+_30296332 0.23 ENSDART00000192843
ugt1b7
UDP glucuronosyltransferase 1 family, polypeptide B7
chr7_+_19904136 0.23 ENSDART00000173452
si:ch211-285j22.3
si:ch211-285j22.3
chr14_-_32089117 0.21 ENSDART00000158014
si:ch211-69b22.5
si:ch211-69b22.5
chr9_+_13714379 0.19 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr1_-_53987766 0.18 ENSDART00000167720
RHOU (1 of many)
si:ch211-133l11.10

Network of associatons between targets according to the STRING database.

First level regulatory network of otx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.9 GO:0031446 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
2.3 6.9 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
1.1 3.4 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.7 2.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.5 4.6 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.5 1.5 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.5 8.6 GO:0016203 muscle attachment(GO:0016203)
0.4 2.1 GO:0007412 axon target recognition(GO:0007412)
0.3 3.1 GO:0006833 water transport(GO:0006833)
0.3 1.7 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 0.9 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.3 3.4 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.3 1.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.3 1.5 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.2 0.7 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.2 1.9 GO:0019430 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 2.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.2 0.9 GO:0007624 ultradian rhythm(GO:0007624)
0.2 0.5 GO:0016038 absorption of visible light(GO:0016038)
0.2 2.1 GO:0050936 xanthophore differentiation(GO:0050936)
0.2 1.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 1.3 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 0.6 GO:0061010 gall bladder development(GO:0061010)
0.1 0.8 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 1.9 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.3 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 1.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.6 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 1.0 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.5 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.5 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 1.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 3.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.8 GO:0071632 optomotor response(GO:0071632)
0.1 2.7 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 1.0 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 1.3 GO:0007634 optokinetic behavior(GO:0007634)
0.1 1.5 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.8 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.3 GO:0061033 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.4 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.6 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 2.1 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 1.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.4 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 1.6 GO:0007602 phototransduction(GO:0007602)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 1.0 GO:0032526 response to retinoic acid(GO:0032526)
0.0 1.4 GO:0036269 swimming behavior(GO:0036269)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.0 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.5 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.8 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.4 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 2.4 GO:0007601 visual perception(GO:0007601)
0.0 5.1 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 1.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.0 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 1.2 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 3.5 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 0.1 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.9 GO:0031673 H zone(GO:0031673)
0.3 1.7 GO:0034359 mature chylomicron(GO:0034359)
0.3 4.6 GO:0071564 npBAF complex(GO:0071564)
0.3 3.3 GO:0044295 axonal growth cone(GO:0044295)
0.3 1.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 5.1 GO:0060170 ciliary membrane(GO:0060170)
0.1 1.6 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 3.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.9 GO:0005922 connexon complex(GO:0005922)
0.1 1.4 GO:0031430 M band(GO:0031430)
0.1 4.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.5 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.4 GO:0016234 inclusion body(GO:0016234)
0.0 2.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 3.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 8.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.3 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.5 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0005502 11-cis retinal binding(GO:0005502)
0.6 10.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.6 1.9 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.5 3.3 GO:0034632 retinol transporter activity(GO:0034632)
0.3 3.1 GO:0015250 water channel activity(GO:0015250)
0.3 1.0 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.3 3.4 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 1.9 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.9 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.2 1.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 1.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.2 0.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 1.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.2 1.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 1.1 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 2.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.1 1.2 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 3.3 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 5.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.6 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 6.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 3.2 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 4.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 1.9 GO:0015293 symporter activity(GO:0015293)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 4.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.3 REACTOME OPSINS Genes involved in Opsins
0.6 10.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 4.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.6 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 4.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts