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PRJNA195909:zebrafish embryo and larva development

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Results for patz1

Z-value: 2.58

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Transcription factors associated with patz1

Gene Symbol Gene ID Gene Info
patz1
ENSDARG00000076584 POZ/BTB and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
patz1dr11_v1_chr6_+_40952031_40952031-0.932.9e-04Click!

Activity profile of patz1 motif

Sorted Z-values of patz1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_5254699 8.88 ENSDART00000081951
stx1b
syntaxin 1B
chr2_+_26179096 5.99 ENSDART00000024662
plppr3a
phospholipid phosphatase related 3a
chr19_+_48111285 5.64 ENSDART00000169420
nme2b.2
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr21_+_26697536 5.26 ENSDART00000004109
gng3
guanine nucleotide binding protein (G protein), gamma 3
chr9_-_44295071 5.07 ENSDART00000011837
neurod1
neuronal differentiation 1
chr12_-_16941319 5.02 ENSDART00000109968
zgc:174855
zgc:174855
chr16_-_42390441 5.00 ENSDART00000148475
cspg5a
chondroitin sulfate proteoglycan 5a
chr21_-_28901095 4.64 ENSDART00000180820
cxxc5a
CXXC finger protein 5a
chr13_+_12045758 4.57 ENSDART00000079398
ENSDART00000165467
ENSDART00000165880
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr12_-_26851726 4.55 ENSDART00000047724
zeb1b
zinc finger E-box binding homeobox 1b
chr12_-_16764751 4.46 ENSDART00000113862
zgc:174154
zgc:174154
chr15_+_1397811 4.33 ENSDART00000102125
schip1
schwannomin interacting protein 1
chr9_-_24413008 4.29 ENSDART00000135897
tmeff2a
transmembrane protein with EGF-like and two follistatin-like domains 2a
chr6_+_55032439 4.12 ENSDART00000164232
ENSDART00000158845
ENSDART00000157584
ENSDART00000026359
ENSDART00000122794
ENSDART00000183742
mybphb
myosin binding protein Hb
chr16_-_42390640 4.11 ENSDART00000193214
ENSDART00000102305
cspg5a
chondroitin sulfate proteoglycan 5a
chr15_-_3736773 4.10 ENSDART00000090624
lpar6a
lysophosphatidic acid receptor 6a
chr1_-_12278522 4.03 ENSDART00000142122
ENSDART00000003825
cplx2l
complexin 2, like
chr7_+_73630751 4.00 ENSDART00000159745
PCP4L1
si:dkey-46i9.1
chr21_+_13861589 3.97 ENSDART00000015629
ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr5_-_31875645 3.93 ENSDART00000098160
tmem119b
transmembrane protein 119b
chr14_+_33458294 3.87 ENSDART00000075278
atp1b4
ATPase Na+/K+ transporting subunit beta 4
chr5_-_36837846 3.85 ENSDART00000032481
ckma
creatine kinase, muscle a
chr1_-_14233815 3.79 ENSDART00000044896
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr14_-_9522364 3.78 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr12_+_31616412 3.59 ENSDART00000124439
cpn1
carboxypeptidase N, polypeptide 1
chr19_+_11985572 3.52 ENSDART00000130537
spag1a
sperm associated antigen 1a
chr12_+_34732262 3.48 ENSDART00000169634
si:dkey-21c1.8
si:dkey-21c1.8
chr8_+_7320298 3.42 ENSDART00000092347
ssuh2rs1
ssu-2 homolog, related sequence 1
chr25_+_5035343 3.36 ENSDART00000011751
parvb
parvin, beta
chr6_+_47424266 3.32 ENSDART00000171087
si:ch211-286o17.1
si:ch211-286o17.1
chr23_+_10347851 3.24 ENSDART00000127667
krt18
keratin 18
chr16_-_21785261 3.19 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr20_-_147574 3.18 ENSDART00000104762
ENSDART00000131635
slc16a10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr2_-_30693742 3.15 ENSDART00000090292
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr1_-_38709551 3.15 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr25_-_13363286 3.09 ENSDART00000163735
ENSDART00000169119
ndrg4
NDRG family member 4
chr8_+_10305400 2.99 ENSDART00000172400
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr17_-_36936856 2.94 ENSDART00000010274
ENSDART00000188887
dpysl5a
dihydropyrimidinase-like 5a
chr13_+_23214100 2.93 ENSDART00000163393
sorbs1
sorbin and SH3 domain containing 1
chr18_-_45736 2.89 ENSDART00000148373
ENSDART00000148950
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr18_-_46010 2.89 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr16_-_24135508 2.85 ENSDART00000171819
ENSDART00000103176
bcam
basal cell adhesion molecule (Lutheran blood group)
chr10_+_10788811 2.85 ENSDART00000101077
ENSDART00000139143
ptgdsa
prostaglandin D2 synthase a
chr1_-_669717 2.80 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr6_+_39370587 2.76 ENSDART00000157165
ENSDART00000155079
si:dkey-195m11.8
si:dkey-195m11.8
chr3_-_5964557 2.75 ENSDART00000184738
BX284638.1

chr5_-_40510397 2.71 ENSDART00000146237
ENSDART00000051065
fsta
follistatin a
chr13_+_41022502 2.69 ENSDART00000026808
dkk1a
dickkopf WNT signaling pathway inhibitor 1a
chr20_-_24963038 2.67 ENSDART00000102788
ENSDART00000159122
epha7
eph receptor A7
chr21_+_28445052 2.66 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr23_-_45501177 2.66 ENSDART00000150103
col24a1
collagen type XXIV alpha 1
chr10_+_31244619 2.65 ENSDART00000145562
ENSDART00000184412
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr15_-_3736149 2.64 ENSDART00000182986
lpar6a
lysophosphatidic acid receptor 6a
chr18_+_14595546 2.63 ENSDART00000080788
wfdc1
WAP four-disulfide core domain 1
chr16_-_13921589 2.59 ENSDART00000023543
rcvrn2
recoverin 2
chr5_-_14326959 2.57 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr13_+_12045475 2.56 ENSDART00000163053
ENSDART00000160812
ENSDART00000158244
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr13_-_31647323 2.54 ENSDART00000135381
six4a
SIX homeobox 4a
chr25_+_21324588 2.49 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr20_+_20672163 2.43 ENSDART00000027758
rtn1b
reticulon 1b
chr13_+_22480496 2.39 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr18_+_44649804 2.39 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr8_+_25767610 2.37 ENSDART00000062406
cacna1sb
calcium channel, voltage-dependent, L type, alpha 1S subunit, b
chr5_-_31901468 2.35 ENSDART00000147814
ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr3_+_23687909 2.35 ENSDART00000046638
hoxb8a
homeobox B8a
chr5_+_67390645 2.35 ENSDART00000014822
ebf2
early B cell factor 2
chr20_-_40319890 2.30 ENSDART00000075112
clvs2
clavesin 2
chr8_+_10304981 2.30 ENSDART00000160766
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr19_+_2726819 2.30 ENSDART00000187122
ENSDART00000112414
rapgef5a
Rap guanine nucleotide exchange factor (GEF) 5a
chr23_-_637347 2.29 ENSDART00000132175
l1camb
L1 cell adhesion molecule, paralog b
chr1_+_59538755 2.27 ENSDART00000166354
sp6
Sp6 transcription factor
chr5_-_46505691 2.27 ENSDART00000111589
ENSDART00000122966
ENSDART00000166907
hapln1a
hyaluronan and proteoglycan link protein 1a
chr3_+_45687266 2.24 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr3_+_12554801 2.23 ENSDART00000167177
ccnf
cyclin F
chr5_-_28606916 2.22 ENSDART00000026107
ENSDART00000137717
tnc
tenascin C
chr13_-_34793487 2.17 ENSDART00000025719
ism1
isthmin 1
chr19_-_9522548 2.15 ENSDART00000045245
ing4
inhibitor of growth family, member 4
chr8_-_40464935 2.15 ENSDART00000040013
myl7
myosin, light chain 7, regulatory
chr24_+_9744012 2.15 ENSDART00000129656
tmem108
transmembrane protein 108
chr25_-_37331513 2.12 ENSDART00000111862
ldlrad3
low density lipoprotein receptor class A domain containing 3
chr15_+_19838458 2.12 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr15_-_21837207 2.11 ENSDART00000089953
sik2b
salt-inducible kinase 2b
chr8_-_14179798 2.10 ENSDART00000040645
ENSDART00000146749
rhoaa
ras homolog gene family, member Aa
chr24_+_5237753 2.10 ENSDART00000106488
ENSDART00000005901
plod2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr7_-_52558495 2.10 ENSDART00000138263
ENSDART00000009938
ENSDART00000174292
ENSDART00000174218
ENSDART00000174335
tcf12
transcription factor 12
chr2_-_44183613 2.10 ENSDART00000079596
cadm3
cell adhesion molecule 3
chr6_+_7249531 2.09 ENSDART00000125912
ENSDART00000083424
ENSDART00000049695
ENSDART00000136088
dzip1
DAZ interacting zinc finger protein 1
chr2_-_44183451 2.05 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr19_+_22216778 2.04 ENSDART00000052521
nfatc1
nuclear factor of activated T cells 1
chr22_-_600016 1.98 ENSDART00000086434
tmcc2
transmembrane and coiled-coil domain family 2
chr19_+_4912817 1.98 ENSDART00000101658
ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr15_-_40175894 1.98 ENSDART00000156632
si:ch211-281l24.3
si:ch211-281l24.3
chr8_+_25351863 1.98 ENSDART00000034092
dnase1l1l
deoxyribonuclease I-like 1-like
chr7_-_18168493 1.97 ENSDART00000127428
peli3
pellino E3 ubiquitin protein ligase family member 3
chr16_+_10918252 1.97 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr5_+_67390115 1.96 ENSDART00000193255
ebf2
early B cell factor 2
chr16_+_31853919 1.96 ENSDART00000133886
atn1
atrophin 1
chr20_+_305035 1.95 ENSDART00000104807
si:dkey-119m7.4
si:dkey-119m7.4
chr9_+_21407987 1.94 ENSDART00000145627
gja3
gap junction protein, alpha 3
chr13_+_4405282 1.94 ENSDART00000148280
prr18
proline rich 18
chr1_-_22834824 1.94 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr7_+_34688527 1.93 ENSDART00000108473
plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr9_+_3429662 1.92 ENSDART00000160977
ENSDART00000114168
ENSDART00000082153
CU469503.1
itga6a

integrin, alpha 6a
chr10_-_27197044 1.92 ENSDART00000137928
auts2a
autism susceptibility candidate 2a
chr13_+_22480857 1.92 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
ldb3a
LIM domain binding 3a
chr17_-_21793113 1.90 ENSDART00000104612
hmx3a
H6 family homeobox 3a
chr7_-_24236364 1.90 ENSDART00000010124
slc7a8a
solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr22_-_22719440 1.88 ENSDART00000166794
nr5a2
nuclear receptor subfamily 5, group A, member 2
chr19_+_5072918 1.86 ENSDART00000037126
eno2
enolase 2
chr21_-_22325124 1.85 ENSDART00000142100
gdpd4b
glycerophosphodiester phosphodiesterase domain containing 4b
chr5_-_37247654 1.85 ENSDART00000112312
lrch2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr7_-_5148388 1.85 ENSDART00000143549
si:ch211-272h9.5
si:ch211-272h9.5
chr5_+_37087583 1.85 ENSDART00000049900
tagln2
transgelin 2
chr2_-_51700709 1.83 ENSDART00000188601
tgm1l1
transglutaminase 1 like 1
chr8_+_29962635 1.83 ENSDART00000007640
ptch1
patched 1
chr15_-_33527631 1.79 ENSDART00000187646
ENSDART00000161151
stard13b
StAR-related lipid transfer (START) domain containing 13b
chr21_+_7823146 1.77 ENSDART00000030579
crhbp
corticotropin releasing hormone binding protein
chr22_+_465269 1.77 ENSDART00000145767
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr16_-_29277164 1.74 ENSDART00000058870
rhbg
Rh family, B glycoprotein (gene/pseudogene)
chr1_-_10647307 1.74 ENSDART00000103548
si:dkey-31e10.1
si:dkey-31e10.1
chr3_-_62380146 1.73 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr24_-_38816725 1.73 ENSDART00000063231
nog2
noggin 2
chr17_+_52822422 1.73 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr23_-_2513300 1.72 ENSDART00000067652
snai1b
snail family zinc finger 1b
chr4_+_19534833 1.70 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr24_-_21258945 1.69 ENSDART00000111025
boc
BOC cell adhesion associated, oncogene regulated
chr11_-_12051805 1.69 ENSDART00000110117
ENSDART00000182744
socs7
suppressor of cytokine signaling 7
chr14_+_24283915 1.68 ENSDART00000172868
klhl3
kelch-like family member 3
chr14_-_33454595 1.67 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr13_-_8229977 1.66 ENSDART00000139728
si:ch211-250c4.4
si:ch211-250c4.4
chr20_+_11800063 1.65 ENSDART00000152230
si:ch211-155o21.4
si:ch211-155o21.4
chr5_+_22969651 1.65 ENSDART00000089992
ENSDART00000145477
hmgn7
high mobility group nucleosomal binding domain 7
chr6_-_47840465 1.64 ENSDART00000141986
lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr7_-_58098814 1.63 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr5_-_52784152 1.63 ENSDART00000169307
fam189a2
family with sequence similarity 189, member A2
chr11_-_3334248 1.61 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr4_+_57093908 1.61 ENSDART00000170198
si:ch211-238e22.5
si:ch211-238e22.5
chr2_-_5399437 1.59 ENSDART00000132411
si:ch1073-184j22.2
si:ch1073-184j22.2
chr4_-_23839789 1.59 ENSDART00000143571
usp6nl
USP6 N-terminal like
chr1_+_54908895 1.58 ENSDART00000145652
golga7ba
golgin A7 family, member Ba
chr8_+_1187928 1.58 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr23_-_45407631 1.57 ENSDART00000148484
ENSDART00000150186
zgc:101853
zgc:101853
chr20_+_37844035 1.56 ENSDART00000041397
flvcr1
feline leukemia virus subgroup C cellular receptor 1
chr22_+_661505 1.56 ENSDART00000149460
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr10_+_41159241 1.53 ENSDART00000141657
anxa4
annexin A4
chr6_+_54142311 1.53 ENSDART00000154115
hmga1b
high mobility group AT-hook 1b
chr20_+_535458 1.50 ENSDART00000152453
dse
dermatan sulfate epimerase
chr3_+_60007703 1.50 ENSDART00000157351
ENSDART00000153928
ENSDART00000155876
si:ch211-110e21.3
si:ch211-110e21.3
chr22_-_20309283 1.49 ENSDART00000182125
ENSDART00000048775
si:dkey-110c1.10
si:dkey-110c1.10
chr1_-_10647484 1.49 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr11_-_12051502 1.49 ENSDART00000183462
socs7
suppressor of cytokine signaling 7
chr23_-_24394719 1.48 ENSDART00000044918
epha2b
eph receptor A2 b
chr13_-_45523026 1.48 ENSDART00000020663
rhd
Rh blood group, D antigen
chr3_+_62126981 1.48 ENSDART00000060527
drc3
dynein regulatory complex subunit 3
chr9_-_24242592 1.47 ENSDART00000039399
cavin2a
caveolae associated protein 2a
chr2_-_23004286 1.47 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr10_+_43188678 1.44 ENSDART00000012522
vcanb
versican b
chr7_-_33350082 1.44 ENSDART00000008785
anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr16_-_46766153 1.44 ENSDART00000115244
MEX3A
mex-3 RNA binding family member A
chr2_+_43469241 1.43 ENSDART00000142078
ENSDART00000098265
nrp1b
neuropilin 1b
chr2_+_1486822 1.41 ENSDART00000132500
c8a
complement component 8, alpha polypeptide
chr10_-_43113731 1.41 ENSDART00000138099
tmem167a
transmembrane protein 167A
chr19_-_41213718 1.40 ENSDART00000077121
pdk4
pyruvate dehydrogenase kinase, isozyme 4
chr6_+_2048920 1.40 ENSDART00000153568
quo
quattro
chr11_-_12051283 1.39 ENSDART00000170516
socs7
suppressor of cytokine signaling 7
chr2_+_3696038 1.37 ENSDART00000150499
ENSDART00000136906
ENSDART00000164152
ENSDART00000128514
ENSDART00000108964
egfra
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr17_-_23446760 1.37 ENSDART00000104715
pcgf5a
polycomb group ring finger 5a
chr1_+_59073203 1.37 ENSDART00000149937
ENSDART00000162201
MFAP4 (1 of many)
zgc:173915
si:zfos-2330d3.3
zgc:173915
chr3_+_16265924 1.36 ENSDART00000122519
st8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr16_+_4658250 1.35 ENSDART00000006212
LIN28A
si:ch1073-284b18.2
chr3_+_16229911 1.35 ENSDART00000121728
rpl19
ribosomal protein L19
chr10_+_33895315 1.34 ENSDART00000142881
fryb
furry homolog b (Drosophila)
chr5_+_22970617 1.34 ENSDART00000192859
hmgn7
high mobility group nucleosomal binding domain 7
chr19_+_233143 1.33 ENSDART00000175273
syngap1a
synaptic Ras GTPase activating protein 1a
chr15_-_21837515 1.33 ENSDART00000185423
sik2b
salt-inducible kinase 2b
chr14_-_29799993 1.33 ENSDART00000133775
ENSDART00000005568
pdlim3b
PDZ and LIM domain 3b
chr21_+_5589923 1.32 ENSDART00000160885
stbd1
starch binding domain 1
chr20_-_16972351 1.32 ENSDART00000148312
ENSDART00000186702
si:ch73-74h11.1
si:ch73-74h11.1
chr22_-_1245226 1.30 ENSDART00000161292
ampd2a
adenosine monophosphate deaminase 2a
chr5_-_44496805 1.30 ENSDART00000110076
gas1a
growth arrest-specific 1a
chr8_+_6954984 1.29 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr3_-_16289826 1.29 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr18_-_16123222 1.28 ENSDART00000061189
sspn
sarcospan (Kras oncogene-associated gene)
chr5_-_38506981 1.26 ENSDART00000097822
atp1b2b
ATPase Na+/K+ transporting subunit beta 2b
chr17_+_1323699 1.26 ENSDART00000172540
adssl1
adenylosuccinate synthase like 1
chr21_+_5801105 1.23 ENSDART00000151225
ENSDART00000184487
ccng2
cyclin G2
chr23_-_28294763 1.23 ENSDART00000139537
znf385a
zinc finger protein 385A
chr8_+_1082100 1.21 ENSDART00000149276
lzts3b
leucine zipper, putative tumor suppressor family member 3b
chr19_-_24555935 1.21 ENSDART00000132660
ENSDART00000162801
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr5_+_30699260 1.21 ENSDART00000012888
atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr11_+_11504014 1.21 ENSDART00000104264
ENSDART00000134806
ENSDART00000132291
zgc:171226
zgc:171226
chr21_+_28478663 1.20 ENSDART00000077887
ENSDART00000134150
slc22a6l
solute carrier family 22 (organic anion transporter), member 6, like
chr4_+_3980247 1.20 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr7_-_32833153 1.19 ENSDART00000099871
ENSDART00000099872
slc17a6b
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr24_+_9475809 1.16 ENSDART00000132688
si:ch211-285f17.1
si:ch211-285f17.1
chr8_-_23776399 1.16 ENSDART00000114800
INAVA
si:ch211-163l21.4
chr12_-_4540564 1.15 ENSDART00000106566
CABZ01030107.1

chr5_-_26466169 1.15 ENSDART00000144035
arvcfb
ARVCF, delta catenin family member b
chr21_-_37733571 1.15 ENSDART00000176214
mpp1
membrane protein, palmitoylated 1
chr7_+_48460239 1.15 ENSDART00000052113
lingo1b
leucine rich repeat and Ig domain containing 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of patz1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
1.8 8.9 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.3 3.9 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
1.3 3.8 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.9 4.6 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.9 9.1 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.9 2.7 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.9 2.6 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.7 2.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.7 4.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.6 1.8 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.6 1.7 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.5 2.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.5 2.6 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.4 2.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.4 1.6 GO:1990697 protein depalmitoleylation(GO:1990697)
0.4 3.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.4 2.0 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.4 1.6 GO:0003161 cardiac conduction system development(GO:0003161)
0.4 1.6 GO:0097037 heme export(GO:0097037)
0.4 1.1 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.4 6.0 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.4 0.4 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.4 2.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005) atrial cardiac muscle cell development(GO:0055014)
0.4 3.9 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3 1.7 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.3 1.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.3 1.0 GO:0019695 choline metabolic process(GO:0019695)
0.3 2.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.3 2.1 GO:0021885 forebrain cell migration(GO:0021885)
0.3 1.5 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.3 3.9 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.3 2.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.3 1.0 GO:1903589 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.3 4.4 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.3 0.8 GO:0042368 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.2 2.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 2.6 GO:0036368 cone photoresponse recovery(GO:0036368)
0.2 1.9 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 1.2 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 1.8 GO:0097106 postsynaptic density organization(GO:0097106)
0.2 1.1 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 3.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.9 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.2 1.0 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.2 4.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 5.3 GO:0007634 optokinetic behavior(GO:0007634)
0.2 8.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.2 2.9 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.2 6.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 2.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 2.4 GO:0032264 IMP salvage(GO:0032264)
0.2 1.4 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 1.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 3.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 3.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 4.3 GO:0070831 basement membrane assembly(GO:0070831)
0.2 2.0 GO:0021754 facial nucleus development(GO:0021754)
0.2 2.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 2.0 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 1.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.6 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 2.7 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.1 1.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 2.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 2.9 GO:0021884 forebrain neuron development(GO:0021884)
0.1 1.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 2.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.9 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 1.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.6 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 4.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.7 GO:0070293 renal absorption(GO:0070293)
0.1 0.7 GO:0036268 swimming(GO:0036268)
0.1 0.8 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 4.2 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 2.7 GO:0042476 odontogenesis(GO:0042476)
0.1 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.4 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 1.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 2.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.4 GO:0071071 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 1.7 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 4.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 2.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.3 GO:0070227 lymphocyte apoptotic process(GO:0070227)
0.1 1.1 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 0.5 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 1.0 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.9 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 0.6 GO:0071711 basement membrane organization(GO:0071711)
0.1 1.2 GO:0018149 peptide cross-linking(GO:0018149)
0.1 5.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 1.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.4 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.7 GO:0035094 response to nicotine(GO:0035094)
0.1 1.4 GO:0019835 cytolysis(GO:0019835)
0.1 0.3 GO:0044209 AMP salvage(GO:0044209)
0.1 4.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 1.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.5 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.4 GO:0002793 positive regulation of peptide secretion(GO:0002793) positive regulation of peptide hormone secretion(GO:0090277)
0.0 0.8 GO:0097178 ruffle organization(GO:0031529) ruffle assembly(GO:0097178)
0.0 0.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 1.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 1.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.6 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 1.0 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 1.4 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.9 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.4 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 1.0 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 0.5 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 1.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.7 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 1.1 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 1.8 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 1.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.4 GO:0048332 mesoderm morphogenesis(GO:0048332)
0.0 0.7 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 3.6 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 2.4 GO:0070509 calcium ion import(GO:0070509)
0.0 0.6 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 2.2 GO:0016573 histone acetylation(GO:0016573)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 2.4 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 1.2 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.6 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.0 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.0 0.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.0 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.7 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 1.9 GO:0006814 sodium ion transport(GO:0006814)
0.0 1.1 GO:0006909 phagocytosis(GO:0006909)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0005592 collagen type XI trimer(GO:0005592)
0.7 12.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.5 5.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.5 5.4 GO:0044295 axonal growth cone(GO:0044295)
0.4 8.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.3 2.1 GO:0070062 extracellular exosome(GO:0070062)
0.2 1.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 4.3 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 0.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 4.4 GO:0043195 terminal bouton(GO:0043195)
0.1 1.9 GO:0005922 connexon complex(GO:0005922)
0.1 1.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.6 GO:0030315 T-tubule(GO:0030315)
0.1 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 4.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.6 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 3.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 4.3 GO:0005814 centriole(GO:0005814)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.9 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.9 GO:0008305 integrin complex(GO:0008305)
0.0 4.0 GO:0030027 lamellipodium(GO:0030027)
0.0 2.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.5 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 2.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.1 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.8 GO:0005581 collagen trimer(GO:0005581)
0.0 4.2 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 34.4 GO:0005615 extracellular space(GO:0005615)
0.0 2.7 GO:0005882 intermediate filament(GO:0005882)
0.0 3.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 21.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.5 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 1.0 GO:0043235 receptor complex(GO:0043235)
0.0 5.2 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.7 2.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.7 2.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.6 2.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.6 12.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.5 2.7 GO:0039706 co-receptor binding(GO:0039706)
0.5 2.7 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.5 6.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.4 1.6 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.4 2.8 GO:0030274 LIM domain binding(GO:0030274)
0.4 1.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.4 5.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.4 2.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 1.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 3.9 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 5.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.3 1.3 GO:2001070 starch binding(GO:2001070)
0.3 0.8 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
0.3 6.7 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 2.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 4.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 1.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 2.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.0 GO:0060182 apelin receptor activity(GO:0060182)
0.2 6.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 8.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 1.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.2 1.6 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 0.6 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.2 1.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 5.8 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.2 1.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 1.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 0.7 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 0.9 GO:0019215 intermediate filament binding(GO:0019215)
0.1 8.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 3.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 3.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.1 GO:0005113 patched binding(GO:0005113)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 2.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 3.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.8 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.8 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 3.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 2.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.3 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 1.3 GO:0048185 activin binding(GO:0048185)
0.1 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 2.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.3 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 1.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 7.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.2 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.1 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.7 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 1.9 GO:0035064 methylated histone binding(GO:0035064)
0.1 3.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 2.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.8 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.4 GO:0031420 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 1.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.6 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.9 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.7 GO:0042562 hormone binding(GO:0042562)
0.0 1.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 1.1 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 2.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 3.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 3.1 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0016408 C-acyltransferase activity(GO:0016408)
0.0 1.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 1.4 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 5.3 PID IL5 PATHWAY IL5-mediated signaling events
0.2 4.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 2.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.7 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.9 PID INSULIN PATHWAY Insulin Pathway
0.1 2.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.7 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.3 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.4 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.5 8.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3 6.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.3 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 1.9 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.2 3.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 4.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 0.4 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 1.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.5 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 2.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 3.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation