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PRJNA195909:zebrafish embryo and larva development

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Results for pax7a+pax7b+prop1

Z-value: 1.25

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Transcription factors associated with pax7a+pax7b+prop1

Gene Symbol Gene ID Gene Info
prop1
ENSDARG00000039756 PROP paired-like homeobox 1
pax7b
ENSDARG00000070818 paired box 7b
pax7a
ENSDARG00000100398 paired box 7a
prop1
ENSDARG00000109950 PROP paired-like homeobox 1
pax7a
ENSDARG00000111233 paired box 7a
prop1
ENSDARG00000114449 PROP paired-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax7bdr11_v1_chr23_+_20863145_20863145-0.901.0e-03Click!
pax7adr11_v1_chr11_+_41242644_41242644-0.826.8e-03Click!
prop1dr11_v1_chr13_+_8677166_8677304-0.752.0e-02Click!

Activity profile of pax7a+pax7b+prop1 motif

Sorted Z-values of pax7a+pax7b+prop1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_34916208 3.43 ENSDART00000187371
ccna1
cyclin A1
chr10_-_34002185 2.03 ENSDART00000046599
zar1l
zygote arrest 1-like
chr2_+_6253246 1.93 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr8_+_45334255 1.72 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr16_+_47207691 1.60 ENSDART00000062507
ica1
islet cell autoantigen 1
chr17_-_4245902 1.60 ENSDART00000151851
gdf3
growth differentiation factor 3
chr22_-_20695237 1.54 ENSDART00000112722
org
oogenesis-related gene
chr9_+_8390737 1.47 ENSDART00000190891
ENSDART00000176877
ENSDART00000144851
ENSDART00000133880
ENSDART00000142233
zgc:113984
zgc:113984
chr10_+_33393829 1.47 ENSDART00000163458
ENSDART00000115379
zgc:153345
zgc:153345
chr7_+_24573721 1.47 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
si:dkeyp-75h12.7
chr25_+_36292057 1.47 ENSDART00000152329
bmb
brambleberry
chr16_-_41646164 1.44 ENSDART00000184257
atp2c1
ATPase secretory pathway Ca2+ transporting 1
chr12_-_33357655 1.44 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr8_-_53044300 1.44 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr14_-_48765262 1.40 ENSDART00000166463
cnot6b
CCR4-NOT transcription complex, subunit 6b
chr10_+_15255198 1.37 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr20_+_54304800 1.34 ENSDART00000121661
zp2.6
zona pellucida glycoprotein 2, tandem duplicate 6
chr21_-_32060993 1.31 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr9_+_8396755 1.29 ENSDART00000043067
zgc:171776
zgc:171776
chr25_+_22320738 1.29 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr10_+_6884627 1.26 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr17_-_6613458 1.25 ENSDART00000175024
si:ch211-189e2.3
si:ch211-189e2.3
chr15_+_12429206 1.25 ENSDART00000168997
tmprss4a
transmembrane protease, serine 4a
chr23_+_32101202 1.20 ENSDART00000000992
zgc:56699
zgc:56699
chr16_+_23303859 1.20 ENSDART00000006093
slc50a1
solute carrier family 50 (sugar efflux transporter), member 1
chr5_-_68333081 1.19 ENSDART00000168786
h1m
linker histone H1M
chr6_-_55399214 1.18 ENSDART00000168367
ctsa
cathepsin A
chr15_+_34934568 1.17 ENSDART00000165210
zgc:66024
zgc:66024
chr8_-_22326744 1.16 ENSDART00000137645
cep104
centrosomal protein 104
chr4_+_25917915 1.16 ENSDART00000138603
vezt
vezatin, adherens junctions transmembrane protein
chr1_-_40102836 1.14 ENSDART00000147317
cntf
ciliary neurotrophic factor
chr5_+_37903790 1.14 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr1_+_35985813 1.13 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
zgc:152968
chr19_+_1688727 1.13 ENSDART00000115136
ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr17_-_40956035 1.11 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr23_+_42272588 1.10 ENSDART00000164907
CABZ01065131.1

chr8_+_11325310 1.09 ENSDART00000142577
fxn
frataxin
chr14_-_14659023 1.07 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr19_+_2835240 1.06 ENSDART00000190838
CDCP1
CUB domain containing protein 1
chr23_-_33679579 1.02 ENSDART00000188674
tfcp2
transcription factor CP2
chr1_-_6085750 1.00 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr12_-_48188928 0.96 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr24_-_25166720 0.96 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr7_+_22313533 0.95 ENSDART00000123457
TMEM102
si:dkey-11f12.2
chr1_-_55068941 0.93 ENSDART00000152143
ENSDART00000152590
peli1a
pellino E3 ubiquitin protein ligase 1a
chr19_-_18127808 0.92 ENSDART00000108627
snx10a
sorting nexin 10a
chr13_-_35808904 0.91 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr23_-_19225709 0.90 ENSDART00000080099
oard1
O-acyl-ADP-ribose deacylase 1
chr2_+_42871831 0.89 ENSDART00000171393
efr3a
EFR3 homolog A (S. cerevisiae)
chr6_-_15491579 0.89 ENSDART00000156439
st6gal2b
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2b
chr10_+_17235370 0.88 ENSDART00000038780
sppl3
signal peptide peptidase 3
chr24_-_29586082 0.88 ENSDART00000136763
vav3a
vav 3 guanine nucleotide exchange factor a
chr9_+_18829360 0.87 ENSDART00000006514
gtf2f2b
general transcription factor IIF, polypeptide 2b
chr19_+_2631565 0.87 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr19_-_42045372 0.87 ENSDART00000144275
trioa
trio Rho guanine nucleotide exchange factor a
chr9_-_27398369 0.86 ENSDART00000186499
tex30
testis expressed 30
chr11_+_6010177 0.86 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
gtpbp3
GTP binding protein 3, mitochondrial
chr12_-_18577983 0.86 ENSDART00000193262
zdhhc4
zinc finger, DHHC-type containing 4
chr19_-_425145 0.85 ENSDART00000164905
dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr12_-_4243268 0.85 ENSDART00000131275
zgc:92313
zgc:92313
chr18_-_26715655 0.85 ENSDART00000181497
malt3
MALT paracaspase 3
chr18_-_15551360 0.85 ENSDART00000159915
ENSDART00000172690
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr15_+_29727799 0.84 ENSDART00000182006
zgc:153372
zgc:153372
chr17_-_21049260 0.84 ENSDART00000155300
ENSDART00000185758
bicc1a
BicC family RNA binding protein 1a
chr6_-_15492030 0.83 ENSDART00000156141
ENSDART00000183992
st6gal2b
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2b
chr20_-_37813863 0.83 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr5_-_20491198 0.82 ENSDART00000183051
ENSDART00000144232
ficd
FIC domain containing
chr13_-_38088627 0.82 ENSDART00000175268
CT027676.1

chr19_-_5103141 0.82 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr3_+_16722014 0.82 ENSDART00000008711
gys1
glycogen synthase 1 (muscle)
chr15_-_16155729 0.82 ENSDART00000192212
si:ch211-259g3.4
si:ch211-259g3.4
chr5_-_68779747 0.82 ENSDART00000192636
ENSDART00000188039
mepce
methylphosphate capping enzyme
chr11_+_12811906 0.82 ENSDART00000123445
rtel1
regulator of telomere elongation helicase 1
chr25_-_18435481 0.81 ENSDART00000004771
poc1b
POC1 centriolar protein B
chr7_+_23515966 0.80 ENSDART00000186893
ENSDART00000186189
zgc:109889
zgc:109889
chr13_+_35474235 0.79 ENSDART00000181927
mkks
McKusick-Kaufman syndrome
chr21_-_2814709 0.79 ENSDART00000097664
SEMA4D
semaphorin 4D
chr6_+_21001264 0.77 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr22_-_19102256 0.77 ENSDART00000171866
ENSDART00000166295
polrmt
polymerase (RNA) mitochondrial (DNA directed)
chr23_+_43770149 0.76 ENSDART00000024313
rnf150b
ring finger protein 150b
chr1_+_16625678 0.76 ENSDART00000164899
pcm1
pericentriolar material 1
chr5_-_11809710 0.74 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
nf2a
neurofibromin 2a (merlin)
chr16_+_9726038 0.74 ENSDART00000192988
ENSDART00000020859
pip5k1ab
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b
chr11_+_31864921 0.74 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr6_+_40922572 0.74 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr15_-_16177603 0.74 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr8_+_11425048 0.73 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr11_+_6009984 0.73 ENSDART00000185680
gtpbp3
GTP binding protein 3, mitochondrial
chr23_+_26026383 0.73 ENSDART00000141553
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr14_+_26247319 0.73 ENSDART00000192793
CCDC69
coiled-coil domain containing 69
chr5_+_1109098 0.72 ENSDART00000166268
LO017790.1

chr12_+_16087077 0.72 ENSDART00000141898
znf281b
zinc finger protein 281b
chr12_-_6880694 0.71 ENSDART00000171846
pcdh15b
protocadherin-related 15b
chr13_+_35528607 0.71 ENSDART00000075414
ENSDART00000112947
wdr27
WD repeat domain 27
chr21_+_31150438 0.69 ENSDART00000065366
st6gal1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr16_-_13281380 0.69 ENSDART00000103882
grin2db
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr24_-_24724233 0.68 ENSDART00000127044
ENSDART00000012399
armc1
armadillo repeat containing 1
chr3_-_26787430 0.68 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr20_+_39250673 0.68 ENSDART00000153003
reps1
RALBP1 associated Eps domain containing 1
chr7_+_5956937 0.68 ENSDART00000170763
hist1h2a4
histone cluster 1 H2A family member 4
chr16_+_2820340 0.67 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
si:dkey-288i20.2
chr17_+_5793248 0.67 ENSDART00000153743
rp1l1a
retinitis pigmentosa 1-like 1a
chr14_+_46177524 0.66 ENSDART00000074116
rab33ba
RAB33B, member RAS oncogene family a
chr23_+_1029450 0.66 ENSDART00000189196
si:zfos-905g2.1
si:zfos-905g2.1
chr23_+_4709607 0.66 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr3_-_15667713 0.66 ENSDART00000026658
zgc:66474
zgc:66474
chr7_-_9873652 0.66 ENSDART00000006343
asb7
ankyrin repeat and SOCS box containing 7
chr15_-_30505607 0.66 ENSDART00000155212
msi2b
musashi RNA-binding protein 2b
chr10_-_28118035 0.65 ENSDART00000190836
ENSDART00000088852
med13a
mediator complex subunit 13a
chr11_+_35171406 0.65 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr24_+_21514283 0.65 ENSDART00000007066
cdk8
cyclin-dependent kinase 8
chr10_-_28117740 0.64 ENSDART00000134491
med13a
mediator complex subunit 13a
chr24_-_2450597 0.64 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr15_-_43284021 0.64 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr11_-_12802123 0.64 ENSDART00000104143
txlng
taxilin gamma
chr3_-_40658820 0.64 ENSDART00000191948
rnf216
ring finger protein 216
chr2_-_42871286 0.63 ENSDART00000087823
adcy8
adenylate cyclase 8 (brain)
chr8_-_7567815 0.63 ENSDART00000132536
hcfc1b
host cell factor C1b
chr8_-_39822917 0.63 ENSDART00000067843
zgc:162025
zgc:162025
chr5_+_6672870 0.63 ENSDART00000126598
pxna
paxillin a
chr10_-_31015535 0.62 ENSDART00000146116
panx3
pannexin 3
chr24_-_34680956 0.62 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr15_+_19900197 0.61 ENSDART00000005221
thap12b
THAP domain containing 12b
chr7_+_6941583 0.61 ENSDART00000160709
ENSDART00000157634
rbm14b
RNA binding motif protein 14b
chr1_-_25370281 0.60 ENSDART00000050445
trim2a
tripartite motif containing 2a
chr21_-_27619701 0.60 ENSDART00000133441
ENSDART00000180100
pcnxl3
pecanex-like 3 (Drosophila)
chr15_-_2519640 0.60 ENSDART00000047013
srprb
signal recognition particle receptor, B subunit
chr22_+_35205017 0.60 ENSDART00000061315
ENSDART00000146430
tsc22d2
TSC22 domain family 2
chr21_+_31150773 0.59 ENSDART00000126205
st6gal1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr9_-_50000144 0.59 ENSDART00000123416
scn1a
sodium channel, voltage-gated, type I, alpha
chr22_+_35275468 0.59 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr25_-_6432463 0.59 ENSDART00000110389
ptpn9a
protein tyrosine phosphatase, non-receptor type 9, a
chr9_-_50001606 0.59 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr16_-_31622777 0.58 ENSDART00000137311
ENSDART00000002930
phf20l1
PHD finger protein 20 like 1
chr13_-_48161568 0.58 ENSDART00000109469
ENSDART00000188052
ENSDART00000193446
ENSDART00000189509
ENSDART00000184810
golga4
golgin A4
chr20_+_29209767 0.58 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr7_-_69185124 0.57 ENSDART00000182217
ENSDART00000191359
usp10
ubiquitin specific peptidase 10
chr20_+_29209926 0.57 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr4_-_2219705 0.57 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr15_-_17025212 0.57 ENSDART00000014465
hip1
huntingtin interacting protein 1
chr17_-_48944465 0.56 ENSDART00000154110
si:ch1073-80i24.3
si:ch1073-80i24.3
chr5_+_28497956 0.56 ENSDART00000191935
nfr
notochord formation related
chr22_+_35275206 0.56 ENSDART00000112234
rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr25_-_27621268 0.56 ENSDART00000146205
ENSDART00000073511
hyal6
hyaluronoglucosaminidase 6
chr16_-_28658341 0.56 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr23_+_28809002 0.55 ENSDART00000134121
ENSDART00000183661
pex14
peroxisomal biogenesis factor 14
chr9_+_48761455 0.55 ENSDART00000139631
abcb11a
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr2_-_3403020 0.55 ENSDART00000092741
snap47
synaptosomal-associated protein, 47
chr6_+_40951227 0.55 ENSDART00000156660
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr13_+_49727333 0.54 ENSDART00000168799
ENSDART00000037559
ggps1
geranylgeranyl diphosphate synthase 1
chr17_+_52612866 0.54 ENSDART00000182828
ENSDART00000191156
ENSDART00000188814
ENSDART00000109891
angel1
angel homolog 1 (Drosophila)
chr16_-_34401412 0.54 ENSDART00000054020
hivep3b
human immunodeficiency virus type I enhancer binding protein 3b
chr13_+_2442841 0.54 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
arfgef3
ARFGEF family member 3
chr23_-_14766902 0.54 ENSDART00000168113
gss
glutathione synthetase
chr9_-_12443726 0.53 ENSDART00000102434
ehhadh
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr8_+_7097929 0.53 ENSDART00000188955
ENSDART00000184772
ENSDART00000109581
abtb1
ankyrin repeat and BTB (POZ) domain containing 1
chr8_+_18555559 0.53 ENSDART00000149523
tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr16_-_41787421 0.52 ENSDART00000147210
si:dkey-199f5.8
si:dkey-199f5.8
chr5_-_66397688 0.52 ENSDART00000161483
hip1rb
huntingtin interacting protein 1 related b
chr21_+_21195487 0.52 ENSDART00000181746
ENSDART00000184832
rictorb
RPTOR independent companion of MTOR, complex 2b
chr9_+_54039006 0.52 ENSDART00000112441
tlr7
toll-like receptor 7
chr12_+_47081783 0.52 ENSDART00000158568
mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr24_-_38110779 0.52 ENSDART00000147783
crp
c-reactive protein, pentraxin-related
chr10_-_13343831 0.51 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr9_-_43644261 0.51 ENSDART00000023684
cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr25_+_34938317 0.51 ENSDART00000042678
vps4a
vacuolar protein sorting 4a homolog A (S. cerevisiae)
chr13_+_8693410 0.51 ENSDART00000138448
ttc7a
tetratricopeptide repeat domain 7A
chr25_+_4855549 0.50 ENSDART00000163839
ap4e1
adaptor-related protein complex 4, epsilon 1 subunit
chr8_-_53926228 0.50 ENSDART00000015554
ubiad1
UbiA prenyltransferase domain containing 1
chr21_+_45502621 0.50 ENSDART00000166719
si:dkey-223p19.2
si:dkey-223p19.2
chr4_+_9055488 0.50 ENSDART00000155385
slc41a2b
solute carrier family 41 (magnesium transporter), member 2b
chr21_-_25801956 0.50 ENSDART00000101219
mettl27
methyltransferase like 27
chr23_-_41965557 0.50 ENSDART00000144183
slc1a7b
solute carrier family 1 (glutamate transporter), member 7b
chr25_-_20666328 0.50 ENSDART00000098076
csk
C-terminal Src kinase
chr5_-_67629263 0.49 ENSDART00000133753
zbtb20
zinc finger and BTB domain containing 20
chr3_-_6519691 0.49 ENSDART00000165273
ENSDART00000179882
ENSDART00000172292
GGA3 (1 of many)
si:ch73-157i16.3
chr22_+_11972786 0.49 ENSDART00000105788
mgat5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr13_+_15838151 0.49 ENSDART00000008987
klc1a
kinesin light chain 1a
chr3_+_52545014 0.48 ENSDART00000018908
slc27a1a
solute carrier family 27 (fatty acid transporter), member 1a
chr8_-_11834287 0.47 ENSDART00000187229
rapgef1a
Rap guanine nucleotide exchange factor (GEF) 1a
chr15_-_23443588 0.47 ENSDART00000170427
ube4a
ubiquitination factor E4A (UFD2 homolog, yeast)
chr13_-_38039871 0.47 ENSDART00000140645
CR456624.1

chr14_-_6286966 0.47 ENSDART00000168174
elp1
elongator complex protein 1
chr18_+_39487486 0.47 ENSDART00000126978
acadl
acyl-CoA dehydrogenase long chain
chr20_-_29864390 0.47 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr25_-_37314700 0.46 ENSDART00000017807
igl4v8
immunoglobulin light 4 variable 8
chr18_-_45761868 0.46 ENSDART00000025423
cstf3
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr22_+_21518528 0.46 ENSDART00000148487
mier2
mesoderm induction early response 1, family member 2
chr4_+_77943184 0.46 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr21_-_36571804 0.46 ENSDART00000138129
wwc1
WW and C2 domain containing 1
chr11_+_17984354 0.46 ENSDART00000179986
rpusd4
RNA pseudouridylate synthase domain containing 4
chr3_-_13461056 0.46 ENSDART00000137678
fbxw9
F-box and WD repeat domain containing 9
chr12_-_2522487 0.46 ENSDART00000022471
ENSDART00000145213
mapk8b
mitogen-activated protein kinase 8b
chr1_-_29139141 0.45 ENSDART00000075546
ENSDART00000133246
hsf2bp
heat shock transcription factor 2 binding protein
chr11_+_41540862 0.45 ENSDART00000173210
kcnab2a
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr15_-_23442891 0.45 ENSDART00000059376
ube4a
ubiquitination factor E4A (UFD2 homolog, yeast)
chr18_+_14619544 0.45 ENSDART00000010821
utp4
UTP4, small subunit processome component
chr17_+_28533102 0.45 ENSDART00000156218
mdga2a
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr7_+_20383841 0.45 ENSDART00000052906
si:dkey-33c9.6
si:dkey-33c9.6
chr7_+_24645186 0.45 ENSDART00000150118
ENSDART00000150233
ENSDART00000087691
gba2
glucosidase, beta (bile acid) 2

Network of associatons between targets according to the STRING database.

First level regulatory network of pax7a+pax7b+prop1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.3 1.7 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.3 1.2 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 1.5 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.3 1.4 GO:0055071 manganese ion homeostasis(GO:0055071)
0.3 0.8 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.3 0.8 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.3 1.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.3 0.8 GO:0006089 lactate metabolic process(GO:0006089)
0.2 1.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 0.9 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 0.5 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.2 0.5 GO:0042373 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.2 0.7 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.2 0.5 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.1 0.4 GO:0021611 facial nerve formation(GO:0021611)
0.1 0.4 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 0.4 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.4 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.8 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 1.9 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.6 GO:0097065 anterior head development(GO:0097065)
0.1 0.5 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.1 0.9 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.5 GO:1903726 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072) negative regulation of phospholipid metabolic process(GO:1903726)
0.1 0.5 GO:0000012 single strand break repair(GO:0000012)
0.1 0.5 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.8 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.1 0.6 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.9 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 1.7 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 1.4 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.2 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.3 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.1 0.2 GO:0044406 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.1 1.3 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.1 1.6 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.3 GO:0014856 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) positive regulation of lamellipodium organization(GO:1902745)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 3.4 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.5 GO:0032475 otolith formation(GO:0032475)
0.1 0.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.8 GO:0061055 myotome development(GO:0061055)
0.1 0.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.6 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 0.9 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 1.0 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.2 GO:0015677 copper ion import(GO:0015677)
0.0 0.7 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.5 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.4 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.0 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 1.6 GO:0001878 response to yeast(GO:0001878)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0098900 regulation of action potential(GO:0098900)
0.0 0.7 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 1.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.1 GO:0006783 heme biosynthetic process(GO:0006783) cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.7 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.4 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.5 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.6 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.0 1.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.6 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.3 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.8 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.7 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.5 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.2 GO:0045905 positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 1.1 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 1.2 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.1 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.3 GO:0021549 cerebellum development(GO:0021549)
0.0 0.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 1.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.3 GO:0072576 liver morphogenesis(GO:0072576)
0.0 0.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 1.4 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.3 GO:0003128 heart field specification(GO:0003128)
0.0 1.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.4 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.2 GO:0006415 translational termination(GO:0006415)
0.0 0.2 GO:0019682 glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.3 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 0.7 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.5 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.4 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.3 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.0 GO:1901004 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.0 0.1 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:1902267 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 3.1 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.1 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.2 0.9 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 0.6 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 0.7 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 1.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.6 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 0.8 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.7 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 1.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.1 0.4 GO:0032838 cell projection cytoplasm(GO:0032838)
0.1 0.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.1 1.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.6 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.0 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0044545 NSL complex(GO:0044545)
0.0 1.3 GO:0043186 P granule(GO:0043186)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818)
0.0 2.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4 3.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 1.4 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.3 1.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 0.8 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.2 1.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 1.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 0.8 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 0.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 0.6 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.2 0.5 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 1.9 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 0.7 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.2 0.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.4 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.4 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 0.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.1 GO:0016530 metallochaperone activity(GO:0016530)
0.1 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.5 GO:0043295 glutathione binding(GO:0043295)
0.1 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 1.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.2 GO:0032143 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 0.5 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.3 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 3.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.2 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.6 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.0 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.2 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.0 0.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 2.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.8 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.8 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.6 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.6 GO:0022829 wide pore channel activity(GO:0022829)
0.0 1.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.6 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0019809 spermidine binding(GO:0019809)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.4 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.7 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 2.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 3.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 2.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.6 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872) phosphofructokinase activity(GO:0008443)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 1.6 GO:0019904 protein domain specific binding(GO:0019904)
0.0 1.1 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 ST P38 MAPK PATHWAY p38 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 0.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis