Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for pdx1_pbx4

Z-value: 1.23

Motif logo

logo of logo of

Transcription factors associated with pdx1_pbx4

Gene Symbol Gene ID Gene Info
pdx1
ENSDARG00000002779 pancreatic and duodenal homeobox 1
pdx1
ENSDARG00000109275 pancreatic and duodenal homeobox 1
pbx4
ENSDARG00000052150 pre-B-cell leukemia transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pbx4dr11_v1_chr3_+_53052769_53052769-0.818.8e-03Click!
pdx1dr11_v1_chr24_+_21684189_21684189-0.571.1e-01Click!

Activity profile of pdx1_pbx4 motif

Sorted Z-values of pdx1_pbx4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_38301080 18.65 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr4_-_9909371 3.06 ENSDART00000102656
si:dkey-22l11.6
si:dkey-22l11.6
chr13_-_5569562 2.56 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr3_+_23752150 2.42 ENSDART00000146636
hoxb2a
homeobox B2a
chr1_+_16144615 2.22 ENSDART00000054707
tusc3
tumor suppressor candidate 3
chr13_-_5568928 2.19 ENSDART00000192679
meis1b
Meis homeobox 1 b
chr2_+_47623202 1.93 ENSDART00000154465
si:ch211-165b10.3
si:ch211-165b10.3
chr3_-_32818607 1.67 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr8_-_16697912 1.65 ENSDART00000076542
rpe65b
retinal pigment epithelium-specific protein 65b
chr15_+_4632782 1.64 ENSDART00000156012
si:dkey-35i13.1
si:dkey-35i13.1
chr1_-_19845378 1.64 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
grhprb
glyoxylate reductase/hydroxypyruvate reductase b
chr13_-_24447332 1.63 ENSDART00000043004
slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr15_-_34567370 1.57 ENSDART00000099793
sostdc1a
sclerostin domain containing 1a
chr23_+_5490854 1.53 ENSDART00000175403
tulp1a
tubby like protein 1a
chr10_-_26744131 1.41 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr12_-_11457625 1.41 ENSDART00000012318
htra1b
HtrA serine peptidase 1b
chr21_-_23308286 1.40 ENSDART00000184419
zbtb16a
zinc finger and BTB domain containing 16a
chr19_-_5345930 1.36 ENSDART00000066620
ENSDART00000151398
krtt1c19e
keratin type 1 c19e
chr5_+_35458190 1.34 ENSDART00000051313
fbp1b
fructose-1,6-bisphosphatase 1b
chr4_-_16333944 1.30 ENSDART00000079523
epyc
epiphycan
chr5_-_20194876 1.22 ENSDART00000122587
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr3_+_33300522 1.18 ENSDART00000114023
hspb9
heat shock protein, alpha-crystallin-related, 9
chr7_+_26629084 1.18 ENSDART00000101044
ENSDART00000173765
hsbp1a
heat shock factor binding protein 1a
chr7_-_8374950 1.17 ENSDART00000057101
aep1
aerolysin-like protein
chr9_-_23217196 1.16 ENSDART00000083567
kif5c
kinesin family member 5C
chr21_+_20715020 1.13 ENSDART00000015224
gadd45gb.1
growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1
chr7_+_29952719 1.13 ENSDART00000173737
tpma
alpha-tropomyosin
chr24_-_6897884 1.12 ENSDART00000080766
dpp6a
dipeptidyl-peptidase 6a
chr12_-_26406323 1.12 ENSDART00000131896
myoz1b
myozenin 1b
chr21_-_43079161 1.11 ENSDART00000144151
jakmip2
janus kinase and microtubule interacting protein 2
chr14_+_35237613 1.10 ENSDART00000163465
ebf3a
early B cell factor 3a
chr4_+_21129752 1.09 ENSDART00000169764
syt1a
synaptotagmin Ia
chr16_+_23978978 1.09 ENSDART00000058964
ENSDART00000135084
apoa2
apolipoprotein A-II
chr1_-_46981134 1.08 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr10_-_39011514 1.07 ENSDART00000075123
pcp4a
Purkinje cell protein 4a
chr3_-_16068236 1.04 ENSDART00000157315
si:dkey-81l17.6
si:dkey-81l17.6
chr1_+_17676745 1.03 ENSDART00000030665
slc25a4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr11_-_5865744 1.02 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr2_+_33368414 1.02 ENSDART00000077462
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr23_-_6641223 1.00 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr20_-_42702832 1.00 ENSDART00000134689
ENSDART00000045816
plg
plasminogen
chr6_+_25213934 0.97 ENSDART00000163440
si:ch73-97h19.2
si:ch73-97h19.2
chr3_+_23726148 0.94 ENSDART00000174580
hoxb3a
homeobox B3a
chr5_-_51619742 0.94 ENSDART00000188537
otpb
orthopedia homeobox b
chr2_-_722156 0.94 ENSDART00000045770
ENSDART00000169498
foxq1a
forkhead box Q1a
chr15_-_21132480 0.93 ENSDART00000078734
ENSDART00000157481
a2ml
alpha-2-macroglobulin-like
chr6_+_15268685 0.93 ENSDART00000128090
ENSDART00000154417
ecrg4b
esophageal cancer related gene 4b
chr13_+_681628 0.91 ENSDART00000016604
abcc2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr7_+_73593814 0.87 ENSDART00000110544
znf219
zinc finger protein 219
chr25_+_20215964 0.87 ENSDART00000139235
tnnt2d
troponin T2d, cardiac
chr20_-_8443425 0.86 ENSDART00000083908
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr2_+_27010439 0.86 ENSDART00000030547
cdh7a
cadherin 7a
chr9_-_45601103 0.86 ENSDART00000180465
agr1
anterior gradient 1
chr2_-_716426 0.85 ENSDART00000028159
foxf2a
forkhead box F2a
chr23_+_4689626 0.85 ENSDART00000131532
gp9
glycoprotein IX (platelet)
chr7_-_8417315 0.84 ENSDART00000173046
jac1
jacalin 1
chr12_-_26064480 0.84 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
ldb3b
LIM domain binding 3b
chr1_-_10071422 0.83 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr19_+_19767567 0.82 ENSDART00000169074
hoxa3a
homeobox A3a
chr15_-_21155641 0.80 ENSDART00000061098
ENSDART00000046443
A2ML1 (1 of many)
si:dkey-105h12.2
chr1_-_46984142 0.80 ENSDART00000125032
pknox1.2
pbx/knotted 1 homeobox 1.2
chr24_+_13735616 0.79 ENSDART00000184267
msc
musculin (activated B-cell factor-1)
chr4_-_2545310 0.79 ENSDART00000150619
ENSDART00000140760
e2f7
E2F transcription factor 7
chr16_+_10776688 0.78 ENSDART00000161969
ENSDART00000172657
atp1a3b
ATPase Na+/K+ transporting subunit alpha 3b
chr2_+_42724404 0.78 ENSDART00000075392
basp1
brain abundant, membrane attached signal protein 1
chr13_+_23282549 0.78 ENSDART00000101134
khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr2_-_10188598 0.78 ENSDART00000189122
dmbx1a
diencephalon/mesencephalon homeobox 1a
chr25_+_20216159 0.77 ENSDART00000048642
tnnt2d
troponin T2d, cardiac
chr24_-_4973765 0.77 ENSDART00000127597
zic1
zic family member 1 (odd-paired homolog, Drosophila)
chr17_+_27434626 0.76 ENSDART00000052446
vgll2b
vestigial-like family member 2b
chr6_+_29791164 0.76 ENSDART00000017424
ptmaa
prothymosin, alpha a
chr21_+_22423286 0.74 ENSDART00000133190
capslb
calcyphosine-like b
chr20_+_15015557 0.73 ENSDART00000039345
myoc
myocilin
chr6_-_49510553 0.73 ENSDART00000166238
rplp2
ribosomal protein, large P2
chr16_-_16152199 0.73 ENSDART00000012718
fabp11b
fatty acid binding protein 11b
chr24_+_18948665 0.72 ENSDART00000106186
prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr25_+_21833287 0.72 ENSDART00000187606
ckmt1
creatine kinase, mitochondrial 1
chr5_+_45007962 0.72 ENSDART00000010786
dmrt2a
doublesex and mab-3 related transcription factor 2a
chr2_+_3809226 0.71 ENSDART00000147261
egfra
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr8_-_20380750 0.71 ENSDART00000113910
adamts10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr7_+_20503344 0.70 ENSDART00000157699
si:dkey-19b23.12
si:dkey-19b23.12
chr21_-_28920245 0.70 ENSDART00000132884
cxxc5a
CXXC finger protein 5a
chr21_+_26390549 0.70 ENSDART00000185643
tmsb
thymosin, beta
chr12_+_39685485 0.69 ENSDART00000163403
LO017650.1

chr22_-_5682494 0.69 ENSDART00000012686
dnase1l4.1
deoxyribonuclease 1 like 4, tandem duplicate 1
chr7_-_52842007 0.69 ENSDART00000182710
map1aa
microtubule-associated protein 1Aa
chr4_+_40427249 0.68 ENSDART00000151927
si:ch211-218h8.3
si:ch211-218h8.3
chr22_+_3223489 0.68 ENSDART00000082011
lim2.2
lens intrinsic membrane protein 2.2
chr17_+_52822831 0.67 ENSDART00000193368
meis2a
Meis homeobox 2a
chr10_+_31244619 0.67 ENSDART00000145562
ENSDART00000184412
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr22_-_16180849 0.67 ENSDART00000090390
vcam1b
vascular cell adhesion molecule 1b
chr22_-_11729350 0.66 ENSDART00000105813
krt222
keratin 222
chr7_+_46252993 0.66 ENSDART00000167149
znf536
zinc finger protein 536
chr22_+_35068046 0.65 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
si:ch73-173h19.3
chr19_-_10395683 0.64 ENSDART00000109488
zgc:194578
zgc:194578
chr22_+_16535575 0.64 ENSDART00000083063
tal1
T-cell acute lymphocytic leukemia 1
chr12_-_31009315 0.64 ENSDART00000133854
tcf7l2
transcription factor 7 like 2
chr19_-_26869103 0.64 ENSDART00000089699
prrt1
proline-rich transmembrane protein 1
chr23_-_11870962 0.64 ENSDART00000143481
si:dkey-178k16.1
si:dkey-178k16.1
chr2_+_2223837 0.64 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr11_-_1509773 0.63 ENSDART00000050762
phactr3b
phosphatase and actin regulator 3b
chr2_+_45068366 0.63 ENSDART00000142175
si:dkey-76d14.2
si:dkey-76d14.2
chr14_+_36231126 0.63 ENSDART00000141766
elovl6
ELOVL fatty acid elongase 6
chr19_-_48312109 0.62 ENSDART00000161103
si:ch73-359m17.9
si:ch73-359m17.9
chr21_-_27338639 0.62 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr8_+_15254564 0.60 ENSDART00000024433
slc5a9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr11_-_6048490 0.60 ENSDART00000066164
plvapb
plasmalemma vesicle associated protein b
chr23_+_36095260 0.60 ENSDART00000127384
hoxc9a
homeobox C9a
chr8_+_44703864 0.59 ENSDART00000016225
star
steroidogenic acute regulatory protein
chr1_-_26294995 0.59 ENSDART00000168594
cxxc4
CXXC finger 4
chr16_+_26777473 0.59 ENSDART00000188870
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr18_+_26899316 0.59 ENSDART00000050230
tspan3a
tetraspanin 3a
chr9_-_22834860 0.59 ENSDART00000146486
neb
nebulin
chr13_+_30912117 0.59 ENSDART00000133138
drgx
dorsal root ganglia homeobox
chr18_+_17418254 0.57 ENSDART00000140191
ces3
carboxylesterase 3
chr18_+_783936 0.57 ENSDART00000193357
rpp25b
ribonuclease P and MRP subunit p25, b
chr5_-_20195350 0.57 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr22_+_24715282 0.57 ENSDART00000088027
ENSDART00000189054
ENSDART00000140430
ssx2ipb
synovial sarcoma, X breakpoint 2 interacting protein b
chr7_-_20453661 0.56 ENSDART00000174001
ntn5
netrin 5
chr15_+_28202170 0.56 ENSDART00000077736
vtna
vitronectin a
chr3_+_40809011 0.54 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr23_+_31933583 0.54 ENSDART00000145639
si:dkey-126g1.9
si:dkey-126g1.9
chr17_-_49800869 0.54 ENSDART00000156264
col12a1a
collagen, type XII, alpha 1a
chr24_-_6078222 0.53 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_-_681116 0.53 ENSDART00000165894
adamts1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr13_-_31296358 0.52 ENSDART00000030946
prdm8
PR domain containing 8
chr8_-_16712111 0.52 ENSDART00000184147
ENSDART00000180419
ENSDART00000076600
rpe65c
retinal pigment epithelium-specific protein 65c
chr5_-_201600 0.52 ENSDART00000158495
CABZ01088906.1

chr18_-_46010 0.52 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr23_+_10146542 0.52 ENSDART00000048073
zgc:171775
zgc:171775
chr4_-_4387012 0.52 ENSDART00000191836
CU468826.3
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr17_+_52822422 0.51 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr12_-_48970299 0.51 ENSDART00000163734
rgrb
retinal G protein coupled receptor b
chr4_-_27301356 0.51 ENSDART00000100444
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr10_+_45345574 0.51 ENSDART00000166085
ppiab
peptidylprolyl isomerase Ab (cyclophilin A)
chr7_-_8408014 0.51 ENSDART00000112492
zgc:194686
zgc:194686
chr13_-_31435137 0.50 ENSDART00000057441
rtn1a
reticulon 1a
chr8_+_6954984 0.50 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr18_-_14860435 0.50 ENSDART00000018502
mapk12a
mitogen-activated protein kinase 12a
chr13_+_22480496 0.49 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr3_+_23738215 0.49 ENSDART00000143981
hoxb3a
homeobox B3a
chr3_-_52644737 0.49 ENSDART00000126180
si:dkey-210j14.3
si:dkey-210j14.3
chr13_+_22479988 0.48 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr8_-_34052019 0.48 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr20_+_19512727 0.47 ENSDART00000063696
atraid
all-trans retinoic acid-induced differentiation factor
chr11_+_36243774 0.47 ENSDART00000023323
zgc:172270
zgc:172270
chr12_-_28881638 0.46 ENSDART00000148459
ENSDART00000039667
ENSDART00000148668
ENSDART00000136593
ENSDART00000139923
ENSDART00000148912
cbx1b
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr13_+_28417297 0.46 ENSDART00000043658
slc2a15a
solute carrier family 2 (facilitated glucose transporter), member 15a
chr14_-_17072736 0.46 ENSDART00000106333
phox2bb
paired-like homeobox 2bb
chr15_-_21239416 0.46 ENSDART00000155787
A2ML1 (1 of many)
si:dkey-105h12.2
chr1_-_8428736 0.46 ENSDART00000138435
ENSDART00000121823
syngr3b
synaptogyrin 3b
chr8_+_22931427 0.46 ENSDART00000063096
sypa
synaptophysin a
chr7_+_15875082 0.46 ENSDART00000192252
ENSDART00000178909
ENSDART00000179616
pax6b
paired box 6b
chr12_-_17201028 0.46 ENSDART00000020541
lipf
lipase, gastric
chr1_+_26071869 0.45 ENSDART00000059264
mxd4
MAX dimerization protein 4
chr3_-_28857195 0.45 ENSDART00000114319
si:ch211-76l23.7
si:ch211-76l23.7
chr10_-_27741793 0.45 ENSDART00000129369
ENSDART00000192440
ENSDART00000189808
ENSDART00000138149
auts2a
si:dkey-33o22.1
autism susceptibility candidate 2a
si:dkey-33o22.1
chr10_+_20128267 0.45 ENSDART00000064615
dmtn
dematin actin binding protein
chr20_-_52199296 0.45 ENSDART00000131806
ENSDART00000143668
hlx1
H2.0-like homeo box 1 (Drosophila)
chr9_+_2002701 0.45 ENSDART00000082329
evx2
even-skipped homeobox 2
chr14_+_34547554 0.45 ENSDART00000074819
gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
chr5_+_46277593 0.44 ENSDART00000045598
zgc:110626
zgc:110626
chr18_-_14836600 0.44 ENSDART00000045232
mtss1la
metastasis suppressor 1-like a
chr4_-_5291256 0.44 ENSDART00000150864
SNAP91 (1 of many)
si:ch211-214j24.9
chr10_+_36026576 0.44 ENSDART00000193786
hmgb1a
high mobility group box 1a
chr19_-_10243148 0.44 ENSDART00000148073
shisa7b
shisa family member 7
chr15_+_13984879 0.44 ENSDART00000159438
zgc:162730
zgc:162730
chr7_+_35229645 0.44 ENSDART00000144327
tppp3
tubulin polymerization-promoting protein family member 3
chr7_+_25036188 0.44 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr24_+_7884880 0.43 ENSDART00000139467
bmp6
bone morphogenetic protein 6
chr14_-_2199573 0.43 ENSDART00000124485
pcdh2ab8
protocadherin 2 alpha b 8
chr13_+_30912385 0.43 ENSDART00000182642
drgx
dorsal root ganglia homeobox
chr17_-_12385308 0.43 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr18_-_38088099 0.43 ENSDART00000146120
luzp2
leucine zipper protein 2
chr14_+_5385855 0.43 ENSDART00000031508
lbx2
ladybird homeobox 2
chr7_-_25697285 0.43 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr8_+_38415374 0.42 ENSDART00000085395
nkx6.3
NK6 homeobox 3
chr9_-_2594410 0.41 ENSDART00000188306
ENSDART00000164276
sp9
sp9 transcription factor
chr10_+_8968203 0.41 ENSDART00000110443
ENSDART00000080772
fstb
follistatin b
chr18_-_46256560 0.41 ENSDART00000171375
si:dkey-244a7.1
si:dkey-244a7.1
chr12_+_28854410 0.41 ENSDART00000152991
nfe2l1b
nuclear factor, erythroid 2-like 1b
chr13_+_22249636 0.41 ENSDART00000108472
ENSDART00000173123
synpo2la
synaptopodin 2-like a
chr17_+_23937262 0.40 ENSDART00000113276
si:ch211-189k9.2
si:ch211-189k9.2
chr16_+_23282655 0.40 ENSDART00000015956
efna1b
ephrin-A1b
chr3_+_23768898 0.40 ENSDART00000110682
hoxb1a
homeobox B1a
chr7_-_68373495 0.40 ENSDART00000167440
zfhx3
zinc finger homeobox 3
chr18_+_13792490 0.40 ENSDART00000136754
cdh13
cadherin 13, H-cadherin (heart)
chr21_-_44104600 0.39 ENSDART00000044599
oatx
organic anion transporter X
chr4_-_25485404 0.39 ENSDART00000041402
pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr19_+_19775757 0.39 ENSDART00000164677
hoxa3a
homeobox A3a
chr19_+_33476557 0.39 ENSDART00000181800
triqk
triple QxxK/R motif containing
chr23_+_216012 0.39 ENSDART00000181115
ENSDART00000004678
ENSDART00000190439
ENSDART00000189322
PDZD4
si:ch73-162j3.4
chr16_-_50229193 0.39 ENSDART00000161782
ENSDART00000010081
etfb
electron-transfer-flavoprotein, beta polypeptide
chr1_+_23784905 0.39 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit2
slit homolog 2 (Drosophila)
chr10_+_439692 0.39 ENSDART00000147740
zdhhc8a
zinc finger, DHHC-type containing 8a
chr18_-_36135799 0.39 ENSDART00000059344
b3gat1a
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
chr15_-_26552652 0.39 ENSDART00000152336
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr10_-_20445549 0.38 ENSDART00000064613
loxl2a
lysyl oxidase-like 2a
chr12_+_9703172 0.38 ENSDART00000091489
ppp1r9bb
protein phosphatase 1, regulatory subunit 9Bb
chr19_-_3973567 0.38 ENSDART00000167580
map7d1b
MAP7 domain containing 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of pdx1_pbx4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:1901825 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.5 1.5 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.4 1.3 GO:0046351 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.4 1.8 GO:0006522 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.3 5.5 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.3 1.0 GO:0042730 fibrinolysis(GO:0042730)
0.3 0.6 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.3 0.9 GO:0070314 G1 to G0 transition(GO:0070314)
0.3 1.0 GO:0015867 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.3 1.0 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.2 0.7 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.2 0.8 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.2 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.2 GO:0060017 parathyroid gland development(GO:0060017)
0.2 1.2 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 0.6 GO:0010226 response to lithium ion(GO:0010226)
0.2 0.9 GO:0021767 mammillary body development(GO:0021767)
0.2 1.1 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 0.7 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 0.4 GO:0021570 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.1 2.2 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.4 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.9 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 1.5 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 0.5 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.5 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 1.0 GO:0006833 water transport(GO:0006833)
0.1 1.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 1.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.2 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.4 GO:0001778 plasma membrane repair(GO:0001778) monocyte activation(GO:0042117)
0.1 0.7 GO:0090104 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.1 0.6 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.1 0.6 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.4 GO:0019626 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.1 0.4 GO:0060546 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.1 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.4 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882)
0.1 1.0 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.3 GO:0086005 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell action potential(GO:0086005) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 0.4 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.3 GO:0001774 microglial cell activation(GO:0001774)
0.1 0.3 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.4 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 0.3 GO:0032965 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.1 0.3 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 1.1 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.3 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 20.8 GO:0060537 muscle tissue development(GO:0060537)
0.1 0.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.5 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 1.0 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 0.2 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.1 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.8 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.1 1.9 GO:0060037 pharyngeal system development(GO:0060037)
0.1 0.2 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.9 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 0.4 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.8 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.4 GO:0043217 myelin maintenance(GO:0043217)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.0 0.3 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.4 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 1.6 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.2 GO:0070376 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 1.6 GO:0031103 axon regeneration(GO:0031103)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.6 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.2 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 1.0 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.7 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 1.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.6 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 1.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.3 GO:0097009 protein localization to cell surface(GO:0034394) energy homeostasis(GO:0097009)
0.0 0.7 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.1 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.0 0.3 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.5 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.1 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.0 0.4 GO:0097178 ruffle organization(GO:0031529) ruffle assembly(GO:0097178)
0.0 0.7 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.3 GO:0006775 fat-soluble vitamin metabolic process(GO:0006775)
0.0 0.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0042026 protein refolding(GO:0042026)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 3.5 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.0 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.0 0.9 GO:0030903 notochord development(GO:0030903)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.2 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.1 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.2 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.2 GO:0009749 response to glucose(GO:0009749)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 1.3 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0002446 neutrophil mediated immunity(GO:0002446) inflammatory response to wounding(GO:0090594)
0.0 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.0 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.5 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 1.2 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.9 GO:0031101 fin regeneration(GO:0031101)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 0.6 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 2.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 1.2 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 4.1 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.8 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.7 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0032433 filopodium tip(GO:0032433)
0.0 1.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.8 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0043679 axon terminus(GO:0043679)
0.0 0.3 GO:0045335 dendritic spine head(GO:0044327) phagocytic vesicle(GO:0045335)
0.0 0.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.5 2.2 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.5 1.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.4 1.3 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.4 1.8 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.4 1.2 GO:0048030 disaccharide binding(GO:0048030)
0.3 1.0 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.2 1.6 GO:0036122 BMP binding(GO:0036122)
0.2 0.6 GO:0004771 sterol esterase activity(GO:0004771)
0.1 1.6 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.4 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 1.1 GO:0015250 water channel activity(GO:0015250)
0.1 1.1 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.8 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.3 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.0 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.3 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 1.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.2 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 1.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 7.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.0 0.4 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0019809 spermidine binding(GO:0019809)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.8 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.0 0.2 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.6 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.5 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0010181 FMN binding(GO:0010181)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.0 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis