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PRJNA195909:zebrafish embryo and larva development

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Results for pgr

Z-value: 1.92

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Transcription factors associated with pgr

Gene Symbol Gene ID Gene Info
pgr
ENSDARG00000035966 progesterone receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pgrdr11_v1_chr18_+_41820039_41820039-0.324.0e-01Click!

Activity profile of pgr motif

Sorted Z-values of pgr motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_21471022 3.60 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr23_+_21459263 3.20 ENSDART00000104209
her4.3
hairy-related 4, tandem duplicate 3
chr9_-_22272181 3.17 ENSDART00000113174
crygm2d7
crystallin, gamma M2d7
chr25_+_31277415 3.15 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr23_-_21453614 2.72 ENSDART00000079274
her4.1
hairy-related 4, tandem duplicate 1
chr18_+_9171778 2.55 ENSDART00000101192
sema3d
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr23_-_45501177 2.50 ENSDART00000150103
col24a1
collagen type XXIV alpha 1
chr5_-_32308526 2.42 ENSDART00000193758
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr9_-_22831836 2.39 ENSDART00000142585
neb
nebulin
chr16_+_23921777 2.35 ENSDART00000163213
apoa4b.3
apolipoprotein A-IV b, tandem duplicate 3
chr14_-_25949713 2.30 ENSDART00000181455
sparc
secreted protein, acidic, cysteine-rich (osteonectin)
chr2_-_29485408 2.24 ENSDART00000013411
cahz
carbonic anhydrase
chr4_-_16406737 2.19 ENSDART00000013085
dcn
decorin
chr23_+_21455152 2.16 ENSDART00000158511
ENSDART00000161321
ENSDART00000160731
ENSDART00000137573
her4.2
hairy-related 4, tandem duplicate 2
chr9_-_33107237 2.14 ENSDART00000013918
casq2
calsequestrin 2
chr5_-_20195350 2.14 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr21_+_25187210 2.09 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
si:dkey-183i3.5
chr20_+_16750177 1.93 ENSDART00000185357
calm1b
calmodulin 1b
chr5_-_67911111 1.92 ENSDART00000051833
gsx1
GS homeobox 1
chr3_-_28048475 1.88 ENSDART00000150888
rbfox1
RNA binding fox-1 homolog 1
chr19_-_42556086 1.85 ENSDART00000051731
si:dkey-267n13.1
si:dkey-267n13.1
chr6_-_40429411 1.80 ENSDART00000156005
ENSDART00000156357
si:dkey-28n18.9
si:dkey-28n18.9
chr23_-_26077038 1.79 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr24_-_33756003 1.77 ENSDART00000079283
tmeff1b
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr2_+_47581997 1.76 ENSDART00000112579
scg2b
secretogranin II (chromogranin C), b
chr15_+_32710300 1.76 ENSDART00000167857
postnb
periostin, osteoblast specific factor b
chr10_-_29903165 1.76 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr10_+_21786656 1.73 ENSDART00000185851
ENSDART00000167219
pcdh1g26
protocadherin 1 gamma 26
chr18_+_16744307 1.71 ENSDART00000179872
ENSDART00000133490
lyve1b
lymphatic vessel endothelial hyaluronic receptor 1b
chr7_-_74090168 1.71 ENSDART00000050528
tyrp1a
tyrosinase-related protein 1a
chr8_+_25902170 1.68 ENSDART00000193130
rhoab
ras homolog gene family, member Ab
chr11_-_1024483 1.68 ENSDART00000017551
slc6a1b
solute carrier family 6 (neurotransmitter transporter), member 1b
chr22_-_26005894 1.68 ENSDART00000105088
pdgfaa
platelet-derived growth factor alpha polypeptide a
chr1_+_44911405 1.66 ENSDART00000182465
wu:fc21g02
wu:fc21g02
chr9_-_42696408 1.61 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr20_+_572037 1.59 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
smyd2b
SET and MYND domain containing 2b
chr22_-_23668356 1.58 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
cfh
complement factor H
chr18_-_6634424 1.58 ENSDART00000062423
ENSDART00000179955
tnni1c
troponin I, skeletal, slow c
chr17_-_6730247 1.58 ENSDART00000031091
vsnl1b
visinin-like 1b
chr22_-_26100282 1.58 ENSDART00000166075
pdgfaa
platelet-derived growth factor alpha polypeptide a
chr20_+_2281933 1.57 ENSDART00000137579
si:ch73-18b11.2
si:ch73-18b11.2
chr15_-_23699737 1.56 ENSDART00000078311
zgc:154093
zgc:154093
chr7_-_27033080 1.54 ENSDART00000173516
nucb2a
nucleobindin 2a
chr4_+_17417111 1.54 ENSDART00000056005
ascl1a
achaete-scute family bHLH transcription factor 1a
chr4_-_16333944 1.52 ENSDART00000079523
epyc
epiphycan
chr20_-_30377221 1.52 ENSDART00000126229
rps7
ribosomal protein S7
chr24_-_27473771 1.48 ENSDART00000139874
cxl34b.11
CX chemokine ligand 34b, duplicate 11
chr13_-_36391496 1.48 ENSDART00000100217
ENSDART00000140243
actn1
actinin, alpha 1
chr24_+_23742690 1.46 ENSDART00000130162
TCF24
transcription factor 24
chr14_-_36862745 1.46 ENSDART00000109293
rnf130
ring finger protein 130
chr6_-_39764995 1.46 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr5_-_51756210 1.45 ENSDART00000163464
lhfpl2b
LHFPL tetraspan subfamily member 2b
chr3_+_23731109 1.44 ENSDART00000131410
hoxb3a
homeobox B3a
chr14_-_2602445 1.43 ENSDART00000166910
etf1a
eukaryotic translation termination factor 1a
chr22_-_15602593 1.42 ENSDART00000036075
tpm4a
tropomyosin 4a
chr5_-_41307550 1.41 ENSDART00000143446
npr3
natriuretic peptide receptor 3
chr14_-_16328331 1.39 ENSDART00000111262
pcdh12
protocadherin 12
chr17_+_26815021 1.36 ENSDART00000086885
asmt2
acetylserotonin O-methyltransferase 2
chr15_+_37197494 1.33 ENSDART00000166203
aplp1
amyloid beta (A4) precursor-like protein 1
chr8_+_23093155 1.33 ENSDART00000063075
zgc:100920
zgc:100920
chr22_-_15602760 1.32 ENSDART00000009054
tpm4a
tropomyosin 4a
chr4_+_18960914 1.31 ENSDART00000139730
impdh1b
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr24_+_3307857 1.31 ENSDART00000106527
gyg1b
glycogenin 1b
chr1_-_5746030 1.30 ENSDART00000150863
nrp2a
neuropilin 2a
chr23_+_36095260 1.30 ENSDART00000127384
hoxc9a
homeobox C9a
chr20_-_30376433 1.30 ENSDART00000190737
rps7
ribosomal protein S7
chr6_+_23887314 1.30 ENSDART00000163188
znf648
zinc finger protein 648
chr7_+_39389273 1.29 ENSDART00000191298
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr15_+_32710094 1.28 ENSDART00000159592
postnb
periostin, osteoblast specific factor b
chr20_+_33904258 1.28 ENSDART00000170930
rxrgb
retinoid X receptor, gamma b
chr11_+_2202987 1.26 ENSDART00000190008
ENSDART00000173139
hoxc6b
homeobox C6b
chr9_-_46842179 1.26 ENSDART00000054137
igfbp5b
insulin-like growth factor binding protein 5b
chr3_+_7001608 1.25 ENSDART00000127809
zmp:0000001228
zmp:0000001228
chr6_-_60031693 1.22 ENSDART00000160275
CABZ01079262.1

chr1_-_20271138 1.20 ENSDART00000185931
ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr10_+_26669177 1.20 ENSDART00000143402
si:ch73-52f15.5
si:ch73-52f15.5
chr6_+_41096058 1.19 ENSDART00000028373
fkbp5
FK506 binding protein 5
chr9_-_18716 1.18 ENSDART00000164763
CABZ01078737.1

chr22_-_24285432 1.16 ENSDART00000164083
si:ch211-117l17.4
si:ch211-117l17.4
chr24_-_38816725 1.14 ENSDART00000063231
nog2
noggin 2
chr2_+_29976419 1.13 ENSDART00000056748
en2b
engrailed homeobox 2b
chr13_-_31622195 1.12 ENSDART00000057432
six1a
SIX homeobox 1a
chr21_-_25601648 1.12 ENSDART00000042578
efemp2b
EGF containing fibulin extracellular matrix protein 2b
chr20_+_29634653 1.12 ENSDART00000101556
asap2b
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2b
chr14_-_25985698 1.12 ENSDART00000172909
ENSDART00000123053
atox1
antioxidant 1 copper chaperone
chr10_+_31938796 1.11 ENSDART00000182579
lhfpl6
LHFPL tetraspan subfamily member 6
chr19_-_2317558 1.11 ENSDART00000190300
sp8a
sp8 transcription factor a
chr7_+_25033924 1.11 ENSDART00000170873
sb:cb1058
sb:cb1058
chr16_-_36099492 1.11 ENSDART00000180905
CU499336.2

chr5_-_28029558 1.11 ENSDART00000078649
abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr5_+_39667272 1.10 ENSDART00000085388
bmp3
bone morphogenetic protein 3
chr3_-_58650057 1.10 ENSDART00000057640
dhrs7ca
dehydrogenase/reductase (SDR family) member 7Ca
chr19_+_19762183 1.10 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr20_-_29483514 1.09 ENSDART00000062370
actc1a
actin, alpha, cardiac muscle 1a
chr2_+_47582681 1.09 ENSDART00000187579
scg2b
secretogranin II (chromogranin C), b
chr20_+_539852 1.09 ENSDART00000185994
dse
dermatan sulfate epimerase
chr14_+_6159162 1.09 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr15_-_24869826 1.09 ENSDART00000127047
tusc5a
tumor suppressor candidate 5a
chr2_+_47582488 1.08 ENSDART00000149967
scg2b
secretogranin II (chromogranin C), b
chr19_-_32641725 1.08 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr18_-_10995410 1.08 ENSDART00000136751
tspan33b
tetraspanin 33b
chr16_-_2414063 1.07 ENSDART00000073621
zgc:152945
zgc:152945
chr2_+_26288301 1.06 ENSDART00000017668
ptbp1a
polypyrimidine tract binding protein 1a
chr6_-_39765546 1.06 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr2_-_32352946 1.06 ENSDART00000144870
ENSDART00000077151
asap1a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr3_-_29977495 1.06 ENSDART00000077111
hsd17b14
hydroxysteroid (17-beta) dehydrogenase 14
chr19_-_29437108 1.05 ENSDART00000052108
ENSDART00000074497
fndc5b
fibronectin type III domain containing 5b
chr4_-_5302162 1.05 ENSDART00000177099
SNAP91 (1 of many)
si:ch211-214j24.9
chr11_+_21910343 1.04 ENSDART00000161485
foxp4
forkhead box P4
chr19_+_48251273 1.04 ENSDART00000157424
CU693379.1

chr14_-_2050057 1.04 ENSDART00000112875
PCDHB15
protocadherin beta 15
chr3_+_20156956 1.04 ENSDART00000125281
ngfra
nerve growth factor receptor a (TNFR superfamily, member 16)
chr3_-_26109322 1.03 ENSDART00000113780
zgc:162612
zgc:162612
chr14_-_2189889 1.02 ENSDART00000181557
ENSDART00000106707
pcdh2ab9
pcdh2ab11
protocadherin 2 alpha b 9
protocadherin 2 alpha b 11
chr15_-_35406564 1.01 ENSDART00000086051
mecom
MDS1 and EVI1 complex locus
chr15_+_28482862 1.01 ENSDART00000015286
ENSDART00000154320
ankrd13b
ankyrin repeat domain 13B
chr2_-_24996441 1.01 ENSDART00000144795
slc35g2a
solute carrier family 35, member G2a
chr20_-_49657134 1.00 ENSDART00000151248
col12a1b
collagen, type XII, alpha 1b
chr21_+_22985078 1.00 ENSDART00000156491
lpar6b
lysophosphatidic acid receptor 6b
chr21_-_26089964 1.00 ENSDART00000027848
tlcd1
TLC domain containing 1
chr19_-_18626952 0.99 ENSDART00000168004
ENSDART00000162034
ENSDART00000165486
ENSDART00000167971
rps18
ribosomal protein S18
chr20_+_6630540 0.99 ENSDART00000138361
tns3.2
tensin 3, tandem duplicate 2
chr1_-_35924495 0.98 ENSDART00000184424
smad1
SMAD family member 1
chr16_-_35975254 0.98 ENSDART00000167537
eva1ba
eva-1 homolog Ba (C. elegans)
chr23_+_21663631 0.98 ENSDART00000066125
dhrs3a
dehydrogenase/reductase (SDR family) member 3a
chr9_+_3429662 0.97 ENSDART00000160977
ENSDART00000114168
ENSDART00000082153
CU469503.1
itga6a

integrin, alpha 6a
chr15_-_17870090 0.97 ENSDART00000155066
atf5b
activating transcription factor 5b
chr21_+_19648814 0.96 ENSDART00000048581
fgf10a
fibroblast growth factor 10a
chr1_-_26398361 0.95 ENSDART00000160183
ppa2
pyrophosphatase (inorganic) 2
chr12_-_1951233 0.95 ENSDART00000005676
ENSDART00000127937
sox9a
SRY (sex determining region Y)-box 9a
chr5_+_20693724 0.95 ENSDART00000141368
si:ch211-240b21.2
si:ch211-240b21.2
chr4_+_77021784 0.95 ENSDART00000135345
ENSDART00000133855
trpm2
transient receptor potential cation channel, subfamily M, member 2
chr4_-_14328997 0.95 ENSDART00000091151
nell2b
neural EGFL like 2b
chr15_+_1796313 0.93 ENSDART00000126253
fam124b
family with sequence similarity 124B
chr7_+_73780936 0.93 ENSDART00000092691
pea15
proliferation and apoptosis adaptor protein 15
chr19_-_47555956 0.93 ENSDART00000114549
actc1a
actin, alpha, cardiac muscle 1a
chr21_+_28478663 0.92 ENSDART00000077887
ENSDART00000134150
slc22a6l
solute carrier family 22 (organic anion transporter), member 6, like
chr1_+_19303241 0.91 ENSDART00000129970
si:dkeyp-118a3.2
si:dkeyp-118a3.2
chr2_-_37893910 0.91 ENSDART00000143027
hbl2
hexose-binding lectin 2
chr22_-_968484 0.90 ENSDART00000105895
cacna1sa
calcium channel, voltage-dependent, L type, alpha 1S subunit, a
chr2_-_30611389 0.90 ENSDART00000142500
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr25_-_210730 0.89 ENSDART00000187580
FP236318.1

chr4_-_11577253 0.89 ENSDART00000144452
net1
neuroepithelial cell transforming 1
chr1_-_23274038 0.89 ENSDART00000181658
rfc1
replication factor C (activator 1) 1
chr25_+_22274642 0.89 ENSDART00000127099
nr2e3
nuclear receptor subfamily 2, group E, member 3
chr5_-_55395964 0.88 ENSDART00000145791
prune2
prune homolog 2 (Drosophila)
chr21_+_25643880 0.87 ENSDART00000192392
ENSDART00000145091
tmem151a
transmembrane protein 151A
chr8_+_39570615 0.87 ENSDART00000142557
lzts1
leucine zipper, putative tumor suppressor 1
chr21_-_22737228 0.87 ENSDART00000151366
fbxo40.2
F-box protein 40, tandem duplicate 2
chr7_+_30823749 0.86 ENSDART00000085661
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr9_+_31752628 0.85 ENSDART00000060054
itgbl1
integrin, beta-like 1
chr1_-_51615437 0.85 ENSDART00000152185
ENSDART00000152237
ENSDART00000129052
ENSDART00000152595
FBXO48
si:dkey-202b17.4
chr7_+_25036188 0.84 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr24_-_8729716 0.84 ENSDART00000183624
tfap2a
transcription factor AP-2 alpha
chr21_-_8369073 0.84 ENSDART00000132599
nek6
NIMA-related kinase 6
chr8_-_39984593 0.84 ENSDART00000140127
asphd2
aspartate beta-hydroxylase domain containing 2
chr19_+_25478203 0.83 ENSDART00000132934
col28a1a
collagen, type XXVIII, alpha 1a
chr20_-_47704973 0.83 ENSDART00000174808
tfap2b
transcription factor AP-2 beta
chr25_+_3564220 0.82 ENSDART00000170005
zgc:194202
zgc:194202
chr8_-_11229523 0.82 ENSDART00000002164
unc45b
unc-45 myosin chaperone B
chr9_-_8454060 0.82 ENSDART00000110158
irs2b
insulin receptor substrate 2b
chr7_+_17229980 0.82 ENSDART00000184910
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr20_-_39735952 0.82 ENSDART00000101049
ENSDART00000137485
ENSDART00000062402
tpd52l1
tumor protein D52-like 1
chr13_+_35745572 0.81 ENSDART00000159690
gpr75
G protein-coupled receptor 75
chr5_+_22970617 0.79 ENSDART00000192859
hmgn7
high mobility group nucleosomal binding domain 7
chr23_-_30781510 0.79 ENSDART00000183364
myt1a
myelin transcription factor 1a
chr7_-_44672095 0.78 ENSDART00000073745
cmtm4
CKLF-like MARVEL transmembrane domain containing 4
chr8_-_18535822 0.78 ENSDART00000100558
nexn
nexilin (F actin binding protein)
chr4_+_8532580 0.78 ENSDART00000162065
wnt5b
wingless-type MMTV integration site family, member 5b
chr18_-_41650648 0.78 ENSDART00000024087
fzd9b
frizzled class receptor 9b
chr24_-_8729531 0.78 ENSDART00000082346
tfap2a
transcription factor AP-2 alpha
chr8_+_20951590 0.76 ENSDART00000138728
si:dkeyp-82a1.1
si:dkeyp-82a1.1
chr7_+_49681040 0.75 ENSDART00000176372
ENSDART00000192172
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr6_-_54815886 0.75 ENSDART00000180793
ENSDART00000007498
tnni1b
troponin I type 1b (skeletal, slow)
chr1_+_45121393 0.75 ENSDART00000142702
muc13a
mucin 13a, cell surface associated
chr19_-_18626515 0.75 ENSDART00000160624
rps18
ribosomal protein S18
chr18_+_29145681 0.75 ENSDART00000089031
ENSDART00000193336
ppfibp2a
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr16_+_16968682 0.75 ENSDART00000111074
si:ch211-120k19.1
si:ch211-120k19.1
chr4_-_17805128 0.74 ENSDART00000128988
spi2
Spi-2 proto-oncogene
chr16_+_16969060 0.73 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
rpl18
si:ch211-120k19.1
ribosomal protein L18
chr5_+_40219964 0.73 ENSDART00000114078
si:dkey-193c22.2
si:dkey-193c22.2
chr13_-_32577386 0.72 ENSDART00000016535
kcns3a
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a
chr2_-_37896965 0.71 ENSDART00000129852
hbl1
hexose-binding lectin 1
chr1_+_9290103 0.71 ENSDART00000055009
uncx4.1
Unc4.1 homeobox (C. elegans)
chr10_+_34394454 0.70 ENSDART00000110121
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr20_-_26420939 0.70 ENSDART00000110883
akap12b
A kinase (PRKA) anchor protein 12b
chr4_+_77810982 0.70 ENSDART00000184697
si:dkey-238k10.3
si:dkey-238k10.3
chr3_+_16612574 0.69 ENSDART00000104481
slc17a7a
solute carrier family 17 (vesicular glutamate transporter), member 7a
chr20_+_30445971 0.69 ENSDART00000153150
myt1la
myelin transcription factor 1-like, a
chr2_+_4207209 0.69 ENSDART00000157903
ENSDART00000166476
gata6
GATA binding protein 6
chr21_+_18353703 0.69 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
si:ch73-287m6.1
chr6_-_54290227 0.68 ENSDART00000050483
SPDEF
SAM pointed domain containing ETS transcription factor
chr10_+_8968203 0.68 ENSDART00000110443
ENSDART00000080772
fstb
follistatin b
chr15_+_58207 0.68 ENSDART00000188397
AXL
AXL receptor tyrosine kinase
chr9_+_34127005 0.67 ENSDART00000167384
ENSDART00000078065
f5
coagulation factor V
chr4_-_40586979 0.67 ENSDART00000189361
si:dkey-207m2.4
si:dkey-207m2.4
chr25_-_27541288 0.67 ENSDART00000187245
spam1
sperm adhesion molecule 1
chr13_-_36535128 0.67 ENSDART00000043312
srsf5a
serine/arginine-rich splicing factor 5a
chr16_+_13855039 0.67 ENSDART00000113764
ENSDART00000143983
zgc:174888
zgc:174888
chr20_-_8419057 0.67 ENSDART00000145841
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of pgr

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.6 13.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.6 2.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.5 2.1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.5 2.1 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.5 3.1 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.5 1.4 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.5 1.4 GO:0030186 melatonin metabolic process(GO:0030186)
0.4 1.3 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.4 2.4 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.4 1.5 GO:0061549 sympathetic ganglion development(GO:0061549)
0.4 1.4 GO:0060467 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.3 2.0 GO:0003272 endocardial cushion formation(GO:0003272)
0.3 1.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.3 1.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 1.1 GO:0014856 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.2 1.0 GO:0055091 phospholipid homeostasis(GO:0055091)
0.2 0.5 GO:0048521 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.2 1.0 GO:0061033 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.2 1.7 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 2.5 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 1.1 GO:0043011 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.2 1.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.2 1.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.7 GO:0042438 melanin biosynthetic process(GO:0042438)
0.2 2.9 GO:0016203 muscle attachment(GO:0016203)
0.2 1.1 GO:0060017 parathyroid gland development(GO:0060017)
0.2 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 0.8 GO:1904105 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.2 1.1 GO:0034389 lipid particle organization(GO:0034389)
0.2 1.6 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.2 1.5 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.2 9.7 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 0.6 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 1.4 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 1.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 1.1 GO:0043092 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.1 5.4 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.9 GO:0060221 pineal gland development(GO:0021982) retinal rod cell differentiation(GO:0060221)
0.1 0.4 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 0.6 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 2.9 GO:0001757 somite specification(GO:0001757) segment specification(GO:0007379)
0.1 1.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 1.3 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 3.9 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 0.4 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.4 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 1.5 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.7 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 1.6 GO:0032925 regulation of activin receptor signaling pathway(GO:0032925)
0.1 2.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.3 GO:0050802 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) circadian sleep/wake cycle, sleep(GO:0050802)
0.1 2.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.8 GO:0050909 sensory perception of taste(GO:0050909)
0.1 1.4 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 0.8 GO:0035094 response to nicotine(GO:0035094)
0.1 0.7 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 2.2 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 1.3 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.1 1.6 GO:0032526 response to retinoic acid(GO:0032526)
0.1 0.2 GO:0003249 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.1 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.5 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.2 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 1.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.2 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.1 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.9 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 1.0 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 1.2 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.3 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.7 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.3 GO:0070293 renal absorption(GO:0070293)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.8 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 2.8 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.4 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 0.3 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.9 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 1.0 GO:0051014 actin filament severing(GO:0051014)
0.0 4.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 1.1 GO:0030901 midbrain development(GO:0030901)
0.0 1.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.8 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0043435 neutrophil homeostasis(GO:0001780) response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.8 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.3 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 4.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.7 GO:0032963 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.8 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.6 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 3.0 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.6 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.6 GO:0048675 axon extension(GO:0048675)
0.0 1.0 GO:0007266 Rho protein signal transduction(GO:0007266)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.4 1.6 GO:0005588 collagen type V trimer(GO:0005588)
0.3 2.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 1.4 GO:0018444 translation release factor complex(GO:0018444)
0.2 2.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 1.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.2 6.8 GO:0005861 troponin complex(GO:0005861)
0.1 1.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 2.0 GO:0005869 dynactin complex(GO:0005869)
0.1 2.8 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.0 GO:0008305 integrin complex(GO:0008305)
0.1 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 5.2 GO:0030018 Z disc(GO:0030018)
0.0 1.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.3 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 4.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 2.7 GO:0005884 actin filament(GO:0005884)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 1.7 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 1.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 19.9 GO:0005615 extracellular space(GO:0005615)
0.0 1.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.7 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 1.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.5 2.1 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.5 1.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.4 1.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 1.1 GO:0046978 TAP1 binding(GO:0046978)
0.4 3.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.3 1.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 0.9 GO:0072570 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.2 1.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 2.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 1.1 GO:0016531 copper chaperone activity(GO:0016531)
0.2 1.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 0.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 2.6 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.5 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.2 0.6 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.2 1.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.0 GO:0005035 death receptor activity(GO:0005035)
0.1 1.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 2.9 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 1.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 4.5 GO:0005518 collagen binding(GO:0005518)
0.1 1.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.5 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.3 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.1 1.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 2.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.5 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.7 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.3 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.1 4.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 6.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0036122 BMP binding(GO:0036122)
0.0 2.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0030251 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.7 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 1.0 GO:0042923 neuropeptide binding(GO:0042923)
0.0 10.0 GO:0051015 actin filament binding(GO:0051015)
0.0 5.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 14.1 GO:0046983 protein dimerization activity(GO:0046983)
0.0 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.8 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 3.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 1.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 1.0 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 11.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.1 GO:0005125 cytokine activity(GO:0005125)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 3.0 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.0 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 ST ADRENERGIC Adrenergic Pathway
0.0 2.9 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 4.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 2.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 2.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation