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PRJNA195909:zebrafish embryo and larva development

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Results for pou2f2a

Z-value: 1.61

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Transcription factors associated with pou2f2a

Gene Symbol Gene ID Gene Info
pou2f2a
ENSDARG00000019658 POU class 2 homeobox 2a
pou2f2a
ENSDARG00000036816 POU class 2 homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou2f2adr11_v1_chr19_-_6239248_6239248-0.383.1e-01Click!

Activity profile of pou2f2a motif

Sorted Z-values of pou2f2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_6081803 2.95 ENSDART00000099224
dld
deltaD
chr14_-_32965169 2.43 ENSDART00000114973
cdx4
caudal type homeobox 4
chr11_-_11575070 2.29 ENSDART00000142208
zgc:110712
zgc:110712
chr17_+_26965351 1.72 ENSDART00000114215
ENSDART00000147192
grhl3
grainyhead-like transcription factor 3
chr23_+_23232136 1.55 ENSDART00000126479
ENSDART00000187764
plekhn1
pleckstrin homology domain containing, family N member 1
chr23_-_31372639 1.54 ENSDART00000179908
ENSDART00000135620
ENSDART00000053367
hmgn3
high mobility group nucleosomal binding domain 3
chr1_-_46832880 1.44 ENSDART00000142406
si:ch73-160h15.3
si:ch73-160h15.3
chr9_-_53666031 1.40 ENSDART00000126314
pcdh8
protocadherin 8
chr1_+_51039558 1.39 ENSDART00000024743
dpy30
dpy-30 histone methyltransferase complex regulatory subunit
chr19_-_340641 1.37 ENSDART00000183848
golph3l
golgi phosphoprotein 3-like
chr10_+_10351685 1.37 ENSDART00000109432
cercam
cerebral endothelial cell adhesion molecule
chr15_-_29387446 1.36 ENSDART00000145976
ENSDART00000035096
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr15_-_29388012 1.35 ENSDART00000115032
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr15_-_16012963 1.33 ENSDART00000144138
hnf1ba
HNF1 homeobox Ba
chr6_+_56147812 1.29 ENSDART00000150219
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr6_-_9581949 1.29 ENSDART00000144335
cyp27c1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr12_+_23424108 1.27 ENSDART00000077732
bambia
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a
chr25_+_22320738 1.25 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr23_+_21473103 1.23 ENSDART00000142921
si:ch73-21g5.7
si:ch73-21g5.7
chr20_+_32669475 1.22 ENSDART00000153337
ENSDART00000153462
si:dkeyp-13d11.1
si:dkeyp-13d11.1
chr4_+_59362813 1.22 ENSDART00000150655
znf1050
zinc finger protein 1050
chr1_-_37701121 1.21 ENSDART00000144669
ENSDART00000140181
si:dkeyp-13d11.1
si:dkeyp-13d11.1
chr4_+_33420247 1.19 ENSDART00000150868
znf1065
zinc finger protein 1065
chr24_-_8730913 1.17 ENSDART00000187228
ENSDART00000082349
ENSDART00000186660
tfap2a
transcription factor AP-2 alpha
chr23_+_12454542 1.15 ENSDART00000182259
ENSDART00000193043
si:ch211-153a8.4
si:ch211-153a8.4
chr2_+_10280645 1.15 ENSDART00000063996
gadd45aa
growth arrest and DNA-damage-inducible, alpha, a
chr14_-_40389699 1.13 ENSDART00000181581
ENSDART00000173398
pcdh19
protocadherin 19
chr24_-_23758003 1.13 ENSDART00000178085
BX640462.2
Danio rerio minichromosome maintenance domain containing 2 (mcmdc2), mRNA.
chr14_+_37545639 1.09 ENSDART00000173192
pcdh1b
protocadherin 1b
chr4_+_64549970 1.07 ENSDART00000167846
si:ch211-223a21.3
si:ch211-223a21.3
chr5_-_42872712 1.05 ENSDART00000003947
flot2a
flotillin 2a
chr17_-_26867725 1.03 ENSDART00000153590
si:dkey-221l4.10
si:dkey-221l4.10
chr11_+_20057182 1.02 ENSDART00000184979
fezf2
FEZ family zinc finger 2
chr8_+_28593707 1.00 ENSDART00000097213
tcf15
transcription factor 15
chr4_+_58695514 0.99 ENSDART00000169840
si:dkey-25i10.1
si:dkey-25i10.1
chr9_-_56272465 0.98 ENSDART00000039235
lcp1
lymphocyte cytosolic protein 1 (L-plastin)
chr11_+_20056732 0.98 ENSDART00000103997
fezf2
FEZ family zinc finger 2
chr4_-_64141714 0.97 ENSDART00000128628
BX914205.3

chr19_+_3653976 0.97 ENSDART00000125673
nedd9
neural precursor cell expressed, developmentally down-regulated 9
chr4_-_42015883 0.96 ENSDART00000163399
znf1145
zinc finger protein 1145
chr8_-_19279784 0.93 ENSDART00000185892
zgc:77486
zgc:77486
chr1_+_54013457 0.92 ENSDART00000012104
ENSDART00000126339
dla
deltaA
chr4_+_43074375 0.91 ENSDART00000150732
znf1137
zinc finger protein 1137
chr10_+_4987766 0.86 ENSDART00000121959
si:ch73-234b20.5
si:ch73-234b20.5
chr3_-_5964557 0.86 ENSDART00000184738
BX284638.1

chr4_+_33191390 0.86 ENSDART00000150429
si:dkey-247i3.6
si:dkey-247i3.6
chr14_+_36226243 0.86 ENSDART00000052569
pitx2
paired-like homeodomain 2
chr20_-_25626693 0.84 ENSDART00000132247
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr4_-_48636872 0.83 ENSDART00000168605
znf1063
zinc finger protein 1063
chr5_-_66028714 0.83 ENSDART00000022625
ENSDART00000164228
nrarpb
NOTCH regulated ankyrin repeat protein b
chr17_-_26868169 0.82 ENSDART00000157204
si:dkey-221l4.10
si:dkey-221l4.10
chr4_+_47656992 0.82 ENSDART00000161148
znf1040
zinc finger protein 1040
chr4_-_45337903 0.81 ENSDART00000159767
si:dkey-247i3.6
si:dkey-247i3.6
chr21_-_44512893 0.79 ENSDART00000166853
zgc:136410
zgc:136410
chr24_-_40774028 0.79 ENSDART00000166578
CU633479.2

chr4_+_32649955 0.79 ENSDART00000135750
znf1042
zinc finger protein 1042
chr1_-_25177086 0.78 ENSDART00000144711
ENSDART00000177225
tmem154
transmembrane protein 154
chr18_+_38749547 0.77 ENSDART00000143735
si:ch211-215d8.2
si:ch211-215d8.2
chr3_+_28581397 0.76 ENSDART00000150893
sept12
septin 12
chr4_+_50726871 0.75 ENSDART00000150469
znf1058
zinc finger protein 1058
chr14_-_42997145 0.74 ENSDART00000172801
pcdh10b
protocadherin 10b
chr2_+_4146299 0.74 ENSDART00000173418
mib1
mindbomb E3 ubiquitin protein ligase 1
chr2_+_4146606 0.74 ENSDART00000171170
mib1
mindbomb E3 ubiquitin protein ligase 1
chr1_+_31725154 0.74 ENSDART00000112333
ENSDART00000189801
cnnm2b
cyclin and CBS domain divalent metal cation transport mediator 2b
chr2_-_30055432 0.73 ENSDART00000056747
shhb
sonic hedgehog b
chr8_-_46060685 0.73 ENSDART00000121902
pimr188
Pim proto-oncogene, serine/threonine kinase, related 188
chr14_-_8080416 0.72 ENSDART00000045109
zgc:92242
zgc:92242
chr8_+_652840 0.71 ENSDART00000187470
LO018102.1

chr23_-_1017428 0.71 ENSDART00000110588
ENSDART00000183158
cdh26.1
cadherin 26, tandem duplicate 1
chr4_+_42078825 0.70 ENSDART00000164496
znf1060
zinc finger protein 1060
chr4_-_4612116 0.70 ENSDART00000130601
CABZ01020840.1
Danio rerio apoptosis facilitator Bcl-2-like protein 14 (LOC101885512), mRNA.
chr22_+_35930526 0.70 ENSDART00000169242
LO016987.1

chr2_-_22993601 0.70 ENSDART00000125049
ENSDART00000099735
mllt1b
MLLT1, super elongation complex subunit b
chr4_+_31259 0.69 ENSDART00000166826
phtf2
putative homeodomain transcription factor 2
chr4_-_50434519 0.68 ENSDART00000150372
znf1061
zinc finger protein 1061
chr4_+_35316044 0.68 ENSDART00000109741
BX000703.1

chr15_+_7187228 0.66 ENSDART00000109394
her13
hairy-related 13
chr4_+_15968483 0.66 ENSDART00000101575
si:dkey-117n7.5
si:dkey-117n7.5
chr5_-_57686487 0.66 ENSDART00000074264
crfb12
cytokine receptor family member B12
chr5_+_54400971 0.65 ENSDART00000169695
bspry
B-box and SPRY domain containing
chr5_+_15202495 0.65 ENSDART00000144915
tbx1
T-box 1
chr6_-_41085692 0.65 ENSDART00000181463
srsf3a
serine/arginine-rich splicing factor 3a
chr23_-_1017605 0.64 ENSDART00000138290
cdh26.1
cadherin 26, tandem duplicate 1
chr12_+_20149707 0.64 ENSDART00000181942
foxj1b
forkhead box J1b
chr4_-_52621232 0.64 ENSDART00000124451
si:dkeyp-104f11.6
si:dkeyp-104f11.6
chr20_+_25626479 0.63 ENSDART00000143883
ppat
phosphoribosyl pyrophosphate amidotransferase
chr17_+_23311377 0.63 ENSDART00000128073
ppp1r3ca
protein phosphatase 1, regulatory subunit 3Ca
chr11_-_30158609 0.63 ENSDART00000006669
scml2
Scm polycomb group protein like 2
chr5_-_34993242 0.62 ENSDART00000134516
ENSDART00000051295
btf3
basic transcription factor 3
chr5_+_15203421 0.62 ENSDART00000040826
tbx1
T-box 1
chr21_+_19070921 0.62 ENSDART00000029874
nkx6.1
NK6 homeobox 1
chr9_+_54178475 0.61 ENSDART00000104475
tmsb4x
thymosin, beta 4 x
chr12_-_34887943 0.60 ENSDART00000027379
bicral
BRD4 interacting chromatin remodeling complex associated protein like
chr19_-_41518922 0.60 ENSDART00000164483
ENSDART00000062080
chrac1
chromatin accessibility complex 1
chr7_-_12065668 0.59 ENSDART00000101537
mex3b
mex-3 RNA binding family member B
chr10_+_29816681 0.59 ENSDART00000100022
h2afx1
H2A histone family member X1
chr4_+_9592486 0.59 ENSDART00000080829
hspa14
heat shock protein 14
chr5_-_66028371 0.59 ENSDART00000183012
nrarpb
NOTCH regulated ankyrin repeat protein b
chr3_-_33422738 0.58 ENSDART00000075493
ccdc103
coiled-coil domain containing 103
chr25_+_36674715 0.58 ENSDART00000111861
mafb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog b (paralog b)
chr25_-_36248053 0.58 ENSDART00000134928
nfatc3b
nuclear factor of activated T cells 3b
chr15_-_25083200 0.57 ENSDART00000156053
pimr191
Pim proto-oncogene, serine/threonine kinase, related 191
chr7_-_29533127 0.57 ENSDART00000057289
anxa2b
annexin A2b
chr6_-_13408680 0.56 ENSDART00000151566
fmnl2b
formin-like 2b
chr5_-_25072607 0.55 ENSDART00000145061
pnpla7b
patatin-like phospholipase domain containing 7b
chr17_-_15777350 0.55 ENSDART00000155711
ankrd6a
ankyrin repeat domain 6a
chr10_-_32610776 0.55 ENSDART00000017436
mogat2
monoacylglycerol O-acyltransferase 2
chr13_+_4440869 0.54 ENSDART00000156323
tbxtb
T-box transcription factor Tb
chr23_-_4925641 0.54 ENSDART00000140861
ENSDART00000060718
taz
tafazzin
chr22_+_13917311 0.54 ENSDART00000022654
sh3bp4a
SH3-domain binding protein 4a
chr4_+_38001640 0.54 ENSDART00000131318
znf1051
zinc finger protein 1051
chr7_+_40228422 0.54 ENSDART00000052222
ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr13_+_18545819 0.53 ENSDART00000101859
ENSDART00000110197
ENSDART00000136064
zgc:154058
zgc:154058
chr14_-_28001986 0.53 ENSDART00000054115
tsc22d3
TSC22 domain family, member 3
chr4_-_73645952 0.52 ENSDART00000182966
si:ch73-266f23.3
si:ch73-266f23.3
chr19_+_12237945 0.51 ENSDART00000190034
grhl2b
grainyhead-like transcription factor 2b
chr23_+_12455295 0.51 ENSDART00000143752
ENSDART00000135785
si:ch211-153a8.4
si:ch211-153a8.4
chr15_-_25010400 0.51 ENSDART00000155236
si:ch211-198e20.10
si:ch211-198e20.10
chr3_+_41558682 0.50 ENSDART00000157023
card11
caspase recruitment domain family, member 11
chr15_-_2803313 0.50 ENSDART00000060839
tgfb1a
transforming growth factor, beta 1a
chr4_-_73351733 0.50 ENSDART00000169597
si:cabz01021426.2
si:cabz01021426.2
chr1_-_25438934 0.50 ENSDART00000111686
fhdc1
FH2 domain containing 1
chr1_-_25438737 0.49 ENSDART00000134470
fhdc1
FH2 domain containing 1
chr8_-_47212686 0.49 ENSDART00000040370
pimr189
Pim proto-oncogene, serine/threonine kinase, related 189
chr10_+_16756546 0.49 ENSDART00000168624
CABZ01024659.1

chr4_-_35989745 0.47 ENSDART00000162568
znf1125
zinc finger protein 1125
chr1_-_51720633 0.47 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr15_-_25039083 0.47 ENSDART00000154409
pimr190
Pim proto-oncogene, serine/threonine kinase, related 190
chr25_-_3830272 0.46 ENSDART00000055843
cd151
CD151 molecule
chr3_-_27646070 0.46 ENSDART00000122031
ENSDART00000151027
si:ch211-157c3.4
si:ch211-157c3.4
chr14_+_35383267 0.46 ENSDART00000143818
clint1a
clathrin interactor 1a
chr4_-_49069087 0.45 ENSDART00000150622
si:ch211-234c11.3
si:ch211-234c11.3
chr7_-_41512999 0.45 ENSDART00000173577
si:dkey-10f23.2
si:dkey-10f23.2
chr4_+_37503994 0.45 ENSDART00000158217
znf1102
zinc finger protein 1102
chr14_-_38929885 0.44 ENSDART00000148737
btk
Bruton agammaglobulinemia tyrosine kinase
chr7_-_4315859 0.44 ENSDART00000172762
si:ch211-63p21.8
si:ch211-63p21.8
chr22_+_15624371 0.43 ENSDART00000124868
lpl
lipoprotein lipase
chr15_-_5165013 0.43 ENSDART00000081653
or126-7
odorant receptor, family E, subfamily 126, member 7
chr4_+_62801285 0.43 ENSDART00000168037
si:dkey-82i20.2
si:dkey-82i20.2
chr13_-_37519774 0.43 ENSDART00000141420
ENSDART00000185478
sgpp1
sphingosine-1-phosphate phosphatase 1
chr10_-_29816467 0.43 ENSDART00000055913
hist2h2l
histone 2, H2, like
chr4_-_48936899 0.42 ENSDART00000121915
znf1064
zinc finger protein 1064
chr13_-_2112008 0.41 ENSDART00000110814
fam83b
family with sequence similarity 83, member B
chr4_-_64605318 0.41 ENSDART00000170391
znf1099
zinc finger protein 1099
chr4_+_11464255 0.41 ENSDART00000008584
gdi2
GDP dissociation inhibitor 2
chr20_+_48782068 0.41 ENSDART00000159275
nkx2.2b
NK2 homeobox 2b
chr4_+_33334774 0.41 ENSDART00000150500
znf1055
zinc finger protein 1055
chr7_+_36041509 0.41 ENSDART00000162850
irx3a
iroquois homeobox 3a
chr12_-_38548299 0.40 ENSDART00000153374
si:dkey-1f1.3
si:dkey-1f1.3
chr3_+_24275766 0.40 ENSDART00000055607
pdgfbb
platelet-derived growth factor beta polypeptide b
chr7_+_4219234 0.40 ENSDART00000187891
ENSDART00000173246
ENSDART00000172808
si:ch211-63p21.4
si:ch211-63p21.4
chr16_-_24550029 0.40 ENSDART00000108590
si:ch211-79k12.1
si:ch211-79k12.1
chr4_-_42014474 0.40 ENSDART00000193544
si:dkey-237m9.1
si:dkey-237m9.1
chr21_+_28502340 0.40 ENSDART00000077897
ENSDART00000140229
otub1a
OTU deubiquitinase, ubiquitin aldehyde binding 1a
chr4_-_56157199 0.40 ENSDART00000169806
si:ch211-207e19.15
si:ch211-207e19.15
chr16_+_17715243 0.40 ENSDART00000149437
ENSDART00000149596
si:dkey-87o1.2
si:dkey-87o1.2
chr5_+_25585869 0.40 ENSDART00000138060
si:dkey-229d2.7
si:dkey-229d2.7
chr11_-_35575791 0.38 ENSDART00000031441
ENSDART00000188513
ENSDART00000183609
sema3fb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb
chr2_+_20926202 0.37 ENSDART00000178880
pla2g4aa
phospholipase A2, group IVAa (cytosolic, calcium-dependent)
chr23_+_9206350 0.37 ENSDART00000136236
si:dkey-66g10.2
si:dkey-66g10.2
chr23_-_6765653 0.37 ENSDART00000192310
FP102169.1

chr14_-_40821411 0.37 ENSDART00000166621
elf1
E74-like ETS transcription factor 1
chr19_+_43256986 0.37 ENSDART00000182336
DGKD
diacylglycerol kinase delta
chr17_+_2162916 0.36 ENSDART00000103775
pak6a
p21 protein (Cdc42/Rac)-activated kinase 6a
chr11_-_42761293 0.36 ENSDART00000183736
CU459094.3

chr22_-_14161309 0.36 ENSDART00000133365
si:ch211-246m6.5
si:ch211-246m6.5
chr19_+_19775757 0.35 ENSDART00000164677
hoxa3a
homeobox A3a
chr19_+_22062202 0.35 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr5_+_58550291 0.35 ENSDART00000184983
ENSDART00000044803
pou2f3
POU class 2 homeobox 3
chr16_+_38167883 0.35 ENSDART00000111796
pi4kb
phosphatidylinositol 4-kinase, catalytic, beta
chr17_+_53311618 0.34 ENSDART00000166517
asb2b
ankyrin repeat and SOCS box containing 2b
chr1_+_46194333 0.34 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr9_-_21507083 0.34 ENSDART00000137922
aff3
AF4/FMR2 family, member 3
chr9_-_34396264 0.34 ENSDART00000045754
grtp1b
growth hormone regulated TBC protein 1b
chr11_-_30158191 0.34 ENSDART00000155278
ENSDART00000156121
scml2
Scm polycomb group protein like 2
chr20_-_22476255 0.34 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr17_+_24722646 0.34 ENSDART00000138356
mtfr1l
mitochondrial fission regulator 1-like
chr15_-_3976035 0.33 ENSDART00000168061
si:ch73-309g22.1
si:ch73-309g22.1
chr19_+_20178978 0.33 ENSDART00000145115
ENSDART00000151175
tra2a
transformer 2 alpha homolog
chr11_+_25010491 0.33 ENSDART00000167285
zgc:92107
zgc:92107
chr13_+_24834199 0.33 ENSDART00000101274
zgc:153981
zgc:153981
chr20_+_18225329 0.33 ENSDART00000144172
kctd1
potassium channel tetramerization domain containing 1
chr21_+_44013487 0.32 ENSDART00000012396
ik
IK cytokine
chr17_+_15297398 0.32 ENSDART00000156574
si:ch211-270g19.5
si:ch211-270g19.5
chr25_+_13791627 0.32 ENSDART00000159278
zgc:92873
zgc:92873
chr20_-_52603094 0.32 ENSDART00000136945
ENSDART00000133798
si:dkey-235d18.6
si:dkey-235d18.6
chr15_+_1148074 0.32 ENSDART00000152638
ENSDART00000152466
ENSDART00000188011
mlf1
myeloid leukemia factor 1
chr25_+_13620555 0.32 ENSDART00000163642
si:ch211-172l8.4
si:ch211-172l8.4
chr20_+_25625872 0.32 ENSDART00000078385
ppat
phosphoribosyl pyrophosphate amidotransferase
chr1_-_1402303 0.32 ENSDART00000130697
runx1
runt-related transcription factor 1
chr21_+_26390549 0.32 ENSDART00000185643
tmsb
thymosin, beta
chr20_+_18993452 0.32 ENSDART00000025509
tdh
L-threonine dehydrogenase
chr4_+_38937575 0.32 ENSDART00000150385
znf997
zinc finger protein 997
chr5_-_33287691 0.31 ENSDART00000004238
rpl7a
ribosomal protein L7a
chr7_+_4194055 0.30 ENSDART00000105073
si:dkey-28d5.14
si:dkey-28d5.14
chr24_+_35827766 0.30 ENSDART00000144700
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr22_+_36656680 0.30 ENSDART00000134031
ENSDART00000056169
b3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr4_-_67712607 0.29 ENSDART00000162955
znf1091
zinc finger protein 1091
chr17_-_27382826 0.29 ENSDART00000186657
ENSDART00000155986
ENSDART00000191060
ENSDART00000077608
si:ch1073-358c10.1
si:ch1073-358c10.1
chr6_-_54111928 0.29 ENSDART00000083880
hyal2a
hyaluronoglucosaminidase 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of pou2f2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.5 1.5 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.5 1.5 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.5 2.4 GO:0003311 pancreatic D cell differentiation(GO:0003311) foregut morphogenesis(GO:0007440)
0.4 1.3 GO:0003156 regulation of organ formation(GO:0003156)
0.4 1.6 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.3 2.0 GO:0021767 mammillary body development(GO:0021767)
0.3 1.3 GO:0048566 embryonic digestive tract development(GO:0048566)
0.3 1.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 0.9 GO:0055016 hypochord development(GO:0055016)
0.2 0.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 1.0 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 2.5 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.2 2.3 GO:0048339 paraxial mesoderm development(GO:0048339)
0.2 2.6 GO:0060325 face morphogenesis(GO:0060325)
0.2 1.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 2.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.7 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.1 0.9 GO:0070254 mucus secretion(GO:0070254)
0.1 1.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.7 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.4 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.1 1.9 GO:0031641 regulation of myelination(GO:0031641)
0.1 1.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.1 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.1 0.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.3 GO:0032965 regulation of collagen metabolic process(GO:0010712) regulation of plasminogen activation(GO:0010755) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.1 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.5 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.3 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 2.6 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.4 GO:1900044 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.4 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 0.6 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.6 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.4 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 1.3 GO:0030168 platelet activation(GO:0030168)
0.1 0.5 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.5 GO:0046471 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:2000191 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.0 0.2 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.6 GO:0042026 protein refolding(GO:0042026)
0.0 0.5 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 0.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0070445 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.0 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.1 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.5 GO:0045682 regulation of epidermis development(GO:0045682)
0.0 0.5 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.2 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0 0.6 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.2 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.2 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.4 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.3 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.0 0.3 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.7 GO:0048854 brain morphogenesis(GO:0048854)
0.0 1.4 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.6 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0034672 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.4 GO:0060872 semicircular canal development(GO:0060872)
0.0 0.1 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.3 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.6 GO:0007596 blood coagulation(GO:0007596)
0.0 0.1 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.4 1.7 GO:0005880 nuclear microtubule(GO:0005880)
0.3 1.1 GO:0016600 flotillin complex(GO:0016600)
0.1 0.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.6 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 1.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.6 GO:0042627 chylomicron(GO:0042627)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 1.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.8 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)
0.0 3.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.5 GO:0030141 secretory granule(GO:0030141)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0030125 clathrin vesicle coat(GO:0030125)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1901612 cardiolipin binding(GO:1901612)
0.4 1.3 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.3 1.4 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 0.8 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.2 1.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 3.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.4 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 1.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.6 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 0.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 1.0 GO:0005113 patched binding(GO:0005113)
0.1 0.3 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 1.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 2.3 GO:0005518 collagen binding(GO:0005518)
0.1 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.6 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.6 GO:2001069 glycogen binding(GO:2001069)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.4 GO:0070697 activin receptor binding(GO:0070697)
0.0 0.1 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 35.6 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 1.0 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 3.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components