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PRJNA195909:zebrafish embryo and larva development

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Results for pou2f3

Z-value: 1.37

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Transcription factors associated with pou2f3

Gene Symbol Gene ID Gene Info
pou2f3
ENSDARG00000052387 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou2f3dr11_v1_chr5_+_58550795_58550795-0.402.9e-01Click!

Activity profile of pou2f3 motif

Sorted Z-values of pou2f3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_30647545 2.61 ENSDART00000114792
gb:eh507706
expressed sequence EH507706
chr7_+_13582256 1.99 ENSDART00000158477
ankdd1a
ankyrin repeat and death domain containing 1A
chr14_+_15155684 1.97 ENSDART00000167966
zgc:158852
zgc:158852
chr17_+_12075805 1.59 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr21_+_36623162 1.58 ENSDART00000027459
grk6
G protein-coupled receptor kinase 6
chr12_+_46543572 1.49 ENSDART00000167510
hid1b
HID1 domain containing b
chr17_-_6641535 1.42 ENSDART00000154540
ENSDART00000180384
si:ch211-189e2.3
si:ch211-189e2.3
chr3_-_59981162 1.42 ENSDART00000128790
cdr2l
cerebellar degeneration-related protein 2-like
chr10_+_34001444 1.40 ENSDART00000149934
kl
klotho
chr11_+_13176568 1.37 ENSDART00000125371
ENSDART00000123257
mknk1
MAP kinase interacting serine/threonine kinase 1
chr19_-_5103313 1.37 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr2_-_42558549 1.35 ENSDART00000025997
dip2cb
disco-interacting protein 2 homolog Cb
chr3_-_46410387 1.32 ENSDART00000156822
cdip1
cell death-inducing p53 target 1
chr19_+_1688727 1.32 ENSDART00000115136
ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr20_+_23625387 1.26 ENSDART00000147945
ENSDART00000150497
palld
palladin, cytoskeletal associated protein
chr19_+_2835240 1.16 ENSDART00000190838
CDCP1
CUB domain containing protein 1
chr5_-_13206878 1.15 ENSDART00000051666
ppm1f
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr14_-_4044545 1.10 ENSDART00000169527
snx25
sorting nexin 25
chr16_+_2820340 1.09 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
si:dkey-288i20.2
chr21_-_3613702 1.09 ENSDART00000139194
dym
dymeclin
chr5_-_65662996 1.05 ENSDART00000147707
camsap1b
calmodulin regulated spectrin-associated protein 1b
chr22_+_18389271 1.05 ENSDART00000088270
yjefn3
YjeF N-terminal domain containing 3
chr14_-_45967981 1.04 ENSDART00000188062
macrod1
MACRO domain containing 1
chr19_+_1510971 1.02 ENSDART00000157721
SLC45A4 (1 of many)
solute carrier family 45 member 4
chr10_+_9595575 1.02 ENSDART00000091780
ENSDART00000184287
rc3h2
ring finger and CCCH-type domains 2
chr21_+_34088377 1.01 ENSDART00000170070
mtmr1b
myotubularin related protein 1b
chr20_-_41992878 1.00 ENSDART00000100967
si:dkeyp-114g9.1
si:dkeyp-114g9.1
chr15_-_23482088 0.99 ENSDART00000185823
ENSDART00000185523
nlrx1
NLR family member X1
chr5_+_45138934 0.98 ENSDART00000041412
ENSDART00000136002
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr20_+_29690901 0.98 ENSDART00000142669
mboat2b
membrane bound O-acyltransferase domain containing 2b
chr3_-_59981476 0.98 ENSDART00000035878
ENSDART00000124038
cdr2l
cerebellar degeneration-related protein 2-like
chr10_-_34002185 0.97 ENSDART00000046599
zar1l
zygote arrest 1-like
chr11_+_25583950 0.96 ENSDART00000111961
ccdc120
coiled-coil domain containing 120
chr22_+_35275468 0.95 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr20_-_43750771 0.95 ENSDART00000100605
ttc32
tetratricopeptide repeat domain 32
chr2_-_55298075 0.94 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr16_-_43011470 0.94 ENSDART00000131898
ENSDART00000142003
ENSDART00000017966
nudt17
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chr20_+_29691118 0.94 ENSDART00000164121
mboat2b
membrane bound O-acyltransferase domain containing 2b
chr5_-_11809710 0.93 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
nf2a
neurofibromin 2a (merlin)
chr13_+_2442841 0.93 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
arfgef3
ARFGEF family member 3
chr23_-_18057270 0.90 ENSDART00000173385
zgc:92287
zgc:92287
chr22_-_20924747 0.90 ENSDART00000185845
ENSDART00000179672
ell
elongation factor RNA polymerase II
chr22_-_20924564 0.90 ENSDART00000100642
ENSDART00000032770
ell
elongation factor RNA polymerase II
chr5_-_16425781 0.89 ENSDART00000185624
ENSDART00000180617
slc39a14
solute carrier family 39 (zinc transporter), member 14
chr24_+_10202718 0.87 ENSDART00000126668
pou6f2
POU class 6 homeobox 2
chr21_+_42717424 0.87 ENSDART00000166936
ENSDART00000172135
sh3pxd2b
SH3 and PX domains 2B
chr7_-_44704910 0.87 ENSDART00000037850
dync1li2
dynein, cytoplasmic 1, light intermediate chain 2
chr9_-_7212973 0.87 ENSDART00000133638
mgat4a
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr11_-_37880492 0.85 ENSDART00000102868
etnk2
ethanolamine kinase 2
chr18_+_3579829 0.84 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr4_-_8903240 0.84 ENSDART00000129983
mpped1
metallophosphoesterase domain containing 1
chr11_+_18053333 0.84 ENSDART00000075750
zgc:175135
zgc:175135
chr19_-_34995629 0.83 ENSDART00000141704
si:rp71-45k5.2
si:rp71-45k5.2
chr20_-_39789036 0.82 ENSDART00000086405
ENSDART00000098253
rnf217
ring finger protein 217
chr2_-_1486023 0.81 ENSDART00000113774
si:ch211-188c16.1
si:ch211-188c16.1
chr8_-_7603700 0.80 ENSDART00000137975
irak1
interleukin-1 receptor-associated kinase 1
chr24_-_25428176 0.79 ENSDART00000090010
phex
phosphate regulating endopeptidase homolog, X-linked
chr23_-_33709964 0.79 ENSDART00000143333
ENSDART00000130338
pou6f1
POU class 6 homeobox 1
chr10_+_26597990 0.79 ENSDART00000079187
fhl1b
four and a half LIM domains 1b
chr19_-_5103141 0.79 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr20_-_49889111 0.78 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr24_-_28333029 0.78 ENSDART00000149015
ENSDART00000129174
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr10_-_14929630 0.78 ENSDART00000121892
ENSDART00000044756
ENSDART00000128579
ENSDART00000147653
smad2
SMAD family member 2
chr2_-_52455525 0.78 ENSDART00000160768
ENSDART00000002241
chico
chico
chr8_-_14052349 0.75 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr8_-_1838315 0.75 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr17_-_17756344 0.74 ENSDART00000190146
adck1
aarF domain containing kinase 1
chr8_-_7603516 0.74 ENSDART00000179826
ENSDART00000190153
irak1
interleukin-1 receptor-associated kinase 1
chr24_-_41220538 0.73 ENSDART00000150207
acvr2ba
activin A receptor type 2Ba
chr15_+_22722684 0.71 ENSDART00000156760
grik4
glutamate receptor, ionotropic, kainate 4
chr4_+_12292274 0.71 ENSDART00000061070
ENSDART00000150786
mkrn1
makorin, ring finger protein, 1
chr24_+_402493 0.71 ENSDART00000036472
VSTM2A
zgc:110852
chr21_+_34088110 0.70 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr10_-_14929392 0.70 ENSDART00000137430
smad2
SMAD family member 2
chr24_-_20641000 0.70 ENSDART00000166135
zbtb47b
zinc finger and BTB domain containing 47b
chr25_-_20666754 0.70 ENSDART00000158418
csk
C-terminal Src kinase
chr18_+_5917625 0.69 ENSDART00000169100
glg1b
golgi glycoprotein 1b
chr10_+_2899108 0.69 ENSDART00000147031
erap1a
endoplasmic reticulum aminopeptidase 1a
chr19_-_31686252 0.68 ENSDART00000131721
ripor2
RHO family interacting cell polarization regulator 2
chr15_-_30815826 0.68 ENSDART00000156160
ENSDART00000145918
msi2b
musashi RNA-binding protein 2b
chr17_-_2595736 0.68 ENSDART00000128797
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_-_10498347 0.68 ENSDART00000171324
mipol1
mirror-image polydactyly 1
chr9_-_32343673 0.68 ENSDART00000078499
rftn2
raftlin family member 2
chr2_-_37632896 0.67 ENSDART00000008302
insra
insulin receptor a
chr4_-_17263210 0.67 ENSDART00000147853
lrmp
lymphoid-restricted membrane protein
chr16_-_46393154 0.67 ENSDART00000132154
si:ch73-59c19.1
si:ch73-59c19.1
chr20_+_9128829 0.67 ENSDART00000064144
ENSDART00000137450
bpnt1
bisphosphate nucleotidase 1
chr25_+_19238175 0.66 ENSDART00000110730
ENSDART00000193619
ENSDART00000154420
ppip5k1b
diphosphoinositol pentakisphosphate kinase 1b
chr10_+_2582254 0.66 ENSDART00000016103
nxnl2
nucleoredoxin like 2
chr4_+_6869847 0.66 ENSDART00000036646
dock4b
dedicator of cytokinesis 4b
chr25_-_3058687 0.66 ENSDART00000149117
ENSDART00000137950
si:ch1073-296i8.2
si:ch1073-296i8.2
chr19_+_15485287 0.66 ENSDART00000182797
pdik1l
PDLIM1 interacting kinase 1 like
chr15_+_29024895 0.65 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
si:ch211-137a8.2
chr3_-_10582384 0.65 ENSDART00000048095
ENSDART00000155152
elac2
elaC ribonuclease Z 2
chr5_-_18897482 0.65 ENSDART00000010101
ENSDART00000099434
aacs
acetoacetyl-CoA synthetase
chr18_-_15551360 0.64 ENSDART00000159915
ENSDART00000172690
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr20_-_1268863 0.64 ENSDART00000109321
ENSDART00000027119
lats1
large tumor suppressor kinase 1
chr5_-_11971946 0.64 ENSDART00000166285
si:ch73-47f2.1
si:ch73-47f2.1
chr24_+_7322116 0.63 ENSDART00000005804
XRCC2
X-ray repair cross complementing 2
chr3_-_15131438 0.63 ENSDART00000131720
xpo6
exportin 6
chr3_-_5067585 0.62 ENSDART00000169609
tefb
thyrotrophic embryonic factor b
chr19_+_43579786 0.62 ENSDART00000138404
si:ch211-199g17.2
si:ch211-199g17.2
chr16_-_31351419 0.62 ENSDART00000178298
ENSDART00000018091
mroh1
maestro heat-like repeat family member 1
chr22_+_14051894 0.62 ENSDART00000142548
aox6
aldehyde oxidase 6
chr1_-_51038885 0.62 ENSDART00000035150
spast
spastin
chr24_-_41267184 0.62 ENSDART00000063504
xylb
xylulokinase homolog (H. influenzae)
chr25_-_20666328 0.61 ENSDART00000098076
csk
C-terminal Src kinase
chr11_+_31680513 0.61 ENSDART00000139900
ENSDART00000040305
diaph3
diaphanous-related formin 3
chr5_-_34964830 0.60 ENSDART00000133170
arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr17_+_24109012 0.60 ENSDART00000156251
ehbp1
EH domain binding protein 1
chr11_+_36409457 0.60 ENSDART00000077641
cyb561d1
cytochrome b561 family, member D1
chr6_-_12902772 0.60 ENSDART00000172237
ical1
islet cell autoantigen 1-like
chr25_+_20272145 0.60 ENSDART00000109605
si:dkey-219c3.2
si:dkey-219c3.2
chr17_-_29213710 0.59 ENSDART00000076481
ehd4
EH-domain containing 4
chr16_-_42770064 0.59 ENSDART00000112879
slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr7_+_33424044 0.59 ENSDART00000180260
glceb
glucuronic acid epimerase b
chr2_+_15048410 0.58 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr21_+_45502621 0.57 ENSDART00000166719
si:dkey-223p19.2
si:dkey-223p19.2
chr25_-_25058508 0.56 ENSDART00000087570
ENSDART00000178891
FQ311928.1

chr7_-_4110462 0.56 ENSDART00000173318
zgc:55733
zgc:55733
chr21_-_43665537 0.56 ENSDART00000157610
si:dkey-229d11.3
si:dkey-229d11.3
chr25_-_13490744 0.56 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr22_-_4439311 0.56 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr4_+_5341592 0.56 ENSDART00000123375
ENSDART00000067371
zgc:113263
zgc:113263
chr16_-_21540077 0.56 ENSDART00000078790
stk31
serine/threonine kinase 31
chr17_-_30975978 0.55 ENSDART00000051697
evla
Enah/Vasp-like a
chr3_-_30885250 0.55 ENSDART00000109104
kmt5c
lysine methyltransferase 5C
chr22_-_817479 0.55 ENSDART00000123487
zgc:153675
zgc:153675
chr1_-_53756851 0.55 ENSDART00000122445
akt3b
v-akt murine thymoma viral oncogene homolog 3b
chr17_-_6076266 0.54 ENSDART00000171084
ephx2
epoxide hydrolase 2, cytoplasmic
chr2_-_3419890 0.54 ENSDART00000055618
iba57
IBA57, iron-sulfur cluster assembly
chr23_+_43638982 0.54 ENSDART00000168646
slc10a7
solute carrier family 10, member 7
chr25_-_27633115 0.54 ENSDART00000131539
hyal6
hyaluronoglucosaminidase 6
chr10_-_31015535 0.54 ENSDART00000146116
panx3
pannexin 3
chr13_+_24022963 0.53 ENSDART00000028285
pgbd5
piggyBac transposable element derived 5
chr12_-_35582683 0.53 ENSDART00000167933
sec24c
SEC24 homolog C, COPII coat complex component
chr25_+_2776511 0.53 ENSDART00000115280
neo1b
neogenin 1b
chr25_+_25516016 0.53 ENSDART00000188980
phrf1
PHD and ring finger domains 1
chr17_-_8570257 0.52 ENSDART00000154713
ENSDART00000121488
fzd3b
frizzled class receptor 3b
chr9_+_12444494 0.52 ENSDART00000102430
tmem41aa
transmembrane protein 41aa
chr24_-_1985007 0.52 ENSDART00000189870
PARD3 (1 of many)
par-3 family cell polarity regulator
chr12_+_48803098 0.51 ENSDART00000074768
ppifb
peptidylprolyl isomerase Fb
chr23_-_25798099 0.51 ENSDART00000041833
fitm2
fat storage-inducing transmembrane protein 2
chr19_-_5805923 0.50 ENSDART00000134340
si:ch211-264f5.8
si:ch211-264f5.8
chr14_+_3495542 0.50 ENSDART00000168934
gstp2
glutathione S-transferase pi 2
chr12_-_11593436 0.50 ENSDART00000138954
plekha1b
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b
chr6_+_32355204 0.50 ENSDART00000157878
dock7
dedicator of cytokinesis 7
chr5_+_44228526 0.50 ENSDART00000143789
TMEM8B
si:dkey-84j12.1
chr5_-_54481692 0.50 ENSDART00000165719
fbxw5
F-box and WD repeat domain containing 5
chr7_+_19600262 0.49 ENSDART00000007310
zgc:171731
zgc:171731
chr2_+_10006839 0.49 ENSDART00000160304
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr5_+_26686279 0.49 ENSDART00000193543
tango2
transport and golgi organization 2 homolog (Drosophila)
chr14_+_15231097 0.48 ENSDART00000172430
si:dkey-203a12.3
si:dkey-203a12.3
chr8_+_8643901 0.48 ENSDART00000142076
ENSDART00000075624
usp11
ubiquitin specific peptidase 11
chr15_-_23485752 0.48 ENSDART00000152706
nlrx1
NLR family member X1
chr8_+_14959587 0.48 ENSDART00000138548
ENSDART00000041697
abl2
c-abl oncogene 2, non-receptor tyrosine kinase
chr18_+_6706140 0.48 ENSDART00000111343
lmf2a
lipase maturation factor 2a
chr23_+_12545114 0.48 ENSDART00000105283
ENSDART00000166990
si:zfos-452g4.1
si:zfos-452g4.1
chr17_-_43623356 0.47 ENSDART00000075596
ENSDART00000136431
rtkn2a
rhotekin 2a
chr17_+_1544903 0.47 ENSDART00000156244
ENSDART00000112183
cep170b
centrosomal protein 170B
chr10_-_31016806 0.47 ENSDART00000027288
panx3
pannexin 3
chr15_+_781717 0.47 ENSDART00000154903
znf970
zinc finger protein 970
chr21_+_43328685 0.46 ENSDART00000109620
ENSDART00000139668
sept8a
septin 8a
chr13_+_47821524 0.46 ENSDART00000109978
zc3h6
zinc finger CCCH-type containing 6
chr17_-_6076084 0.46 ENSDART00000058890
ephx2
epoxide hydrolase 2, cytoplasmic
chr13_+_8696825 0.46 ENSDART00000109059
ttc7a
tetratricopeptide repeat domain 7A
chr21_-_13123176 0.45 ENSDART00000144866
ENSDART00000024616
fam219aa
family with sequence similarity 219, member Aa
chr25_+_4787431 0.45 ENSDART00000170640
myo5c
myosin VC
chr25_-_37248795 0.45 ENSDART00000087247
ENSDART00000154045
glg1a
golgi glycoprotein 1a
chr8_+_17143501 0.45 ENSDART00000061758
mier3b
mesoderm induction early response 1, family member 3 b
chr7_+_30725473 0.44 ENSDART00000085716
mtmr10
myotubularin related protein 10
chr8_+_52314542 0.44 ENSDART00000013059
ENSDART00000125241
dbnlb
drebrin-like b
chr19_-_205104 0.44 ENSDART00000011890
zbtb22a
zinc finger and BTB domain containing 22a
chr20_-_4031475 0.44 ENSDART00000112053
fam89a
family with sequence similarity 89, member A
chr3_-_39305291 0.44 ENSDART00000102674
plcd3a
phospholipase C, delta 3a
chr5_-_64355227 0.44 ENSDART00000170787
fam78aa
family with sequence similarity 78, member Aa
chr3_+_48473346 0.43 ENSDART00000166294
metrnl
meteorin, glial cell differentiation regulator-like
chr11_+_30817943 0.43 ENSDART00000150130
ENSDART00000159997
cacna1ab
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr8_+_30112655 0.43 ENSDART00000099027
fancc
Fanconi anemia, complementation group C
chr24_+_34970680 0.43 ENSDART00000113014
rb1cc1
RB1-inducible coiled-coil 1
chr5_+_44190974 0.42 ENSDART00000182634
ENSDART00000190626
TMEM8B
si:dkey-84j12.1
chr23_-_35066816 0.42 ENSDART00000168731
ENSDART00000163731
BX294434.1

chr21_-_39177564 0.42 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr11_-_12801157 0.42 ENSDART00000103449
txlng
taxilin gamma
chr11_-_12800945 0.42 ENSDART00000191178
txlng
taxilin gamma
chr11_+_1608348 0.42 ENSDART00000162438
si:dkey-40c23.3
si:dkey-40c23.3
chr3_+_51563695 0.42 ENSDART00000008607
ttyh2l
tweety homolog 2, like
chr10_+_15408501 0.41 ENSDART00000123818
ENSDART00000192395
ENSDART00000003839
nln
neurolysin (metallopeptidase M3 family)
chr16_-_6944927 0.41 ENSDART00000149620
pmvk
phosphomevalonate kinase
chr10_-_36793412 0.41 ENSDART00000185966
dhrs13a.2
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 2
chr5_+_6954162 0.41 ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr10_-_32877348 0.40 ENSDART00000018977
ENSDART00000133421
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1
chr10_-_35103208 0.40 ENSDART00000192734
zgc:110006
zgc:110006
chr12_+_48480632 0.40 ENSDART00000158157
arhgap44
Rho GTPase activating protein 44
chr6_-_24053404 0.40 ENSDART00000168511
si:dkey-44g17.6
si:dkey-44g17.6
chr8_+_28900689 0.40 ENSDART00000141634
grid2
glutamate receptor, ionotropic, delta 2
chr11_+_2687395 0.39 ENSDART00000082510
b3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr1_+_47499888 0.39 ENSDART00000027624
stn1
STN1, CST complex subunit
chr25_+_34915762 0.39 ENSDART00000191776
sntb2
syntrophin, beta 2
chr19_-_25114701 0.39 ENSDART00000149035
ptp4a3
protein tyrosine phosphatase type IVA, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of pou2f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.5 1.6 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 1.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.3 0.9 GO:0019677 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.3 1.8 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 0.9 GO:0033212 iron assimilation(GO:0033212)
0.3 1.3 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.3 1.0 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 1.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 0.9 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 0.7 GO:2000402 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.2 0.7 GO:0035046 pronuclear migration(GO:0035046)
0.2 0.7 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.2 0.6 GO:0051228 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.2 0.6 GO:0005997 xylulose metabolic process(GO:0005997)
0.2 0.6 GO:0006089 lactate metabolic process(GO:0006089)
0.2 0.6 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.2 0.9 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.2 1.5 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.2 1.0 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 0.6 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.1 0.9 GO:0071800 podosome assembly(GO:0071800)
0.1 1.2 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.1 1.0 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.4 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 0.2 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 0.4 GO:0032814 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1 0.3 GO:0042182 ketone catabolic process(GO:0042182) L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.8 GO:0071467 cellular response to pH(GO:0071467)
0.1 1.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 0.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.3 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.3 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 0.5 GO:0009109 coenzyme catabolic process(GO:0009109)
0.1 0.2 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.1 0.8 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 0.3 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.2 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.3 GO:0045822 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.1 0.7 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.2 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 0.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.6 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 0.4 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.6 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.5 GO:0032196 transposition(GO:0032196)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.4 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.0 0.7 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0034650 glucocorticoid biosynthetic process(GO:0006704) cortisol metabolic process(GO:0034650)
0.0 1.1 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.2 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.0 0.5 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.0 0.7 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 1.2 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.2 GO:0055021 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.0 0.7 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.6 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.7 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 2.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.8 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.2 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.1 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.0 0.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.2 GO:0032475 otolith formation(GO:0032475)
0.0 0.8 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.3 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.3 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.4 GO:0016233 telomere capping(GO:0016233)
0.0 0.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 1.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.0 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.4 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 1.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.1 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.3 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.4 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.0 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.3 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.6 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.0 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.8 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.7 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.3 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.3 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 1.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.6 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 1.1 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.4 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.2 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 1.4 GO:0051604 protein maturation(GO:0051604)
0.0 0.5 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280)
0.0 1.4 GO:0030258 lipid modification(GO:0030258)
0.0 0.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.6 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.1 GO:0030214 hyaluronan catabolic process(GO:0030214)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 0.7 GO:0060171 stereocilium membrane(GO:0060171)
0.1 1.4 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.7 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:1990879 CST complex(GO:1990879)
0.1 0.3 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.3 GO:0002102 podosome(GO:0002102)
0.1 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.6 GO:0070187 telosome(GO:0070187)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.6 GO:0000792 heterochromatin(GO:0000792)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.7 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 0.9 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0070461 SAGA-type complex(GO:0070461)
0.0 0.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.0 GO:0005769 early endosome(GO:0005769)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.4 1.6 GO:0071253 connexin binding(GO:0071253)
0.3 1.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.3 0.9 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.2 0.6 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.2 0.6 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2 0.9 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 0.7 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.6 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.1 1.0 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.7 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 0.4 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.4 GO:0030882 lipid antigen binding(GO:0030882)
0.1 1.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 1.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.5 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.2 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.6 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.1 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 1.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 1.0 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 1.0 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.7 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.0 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.2 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.1 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.4 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 1.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.9 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 1.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.7 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.1 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.8 GO:0016208 AMP binding(GO:0016208)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 1.0 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.2 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 3.3 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 1.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 0.7 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 1.4 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 0.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport