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PRJNA195909:zebrafish embryo and larva development

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Results for pparaa+pparda+ppardb

Z-value: 1.45

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Transcription factors associated with pparaa+pparda+ppardb

Gene Symbol Gene ID Gene Info
ppardb
ENSDARG00000009473 peroxisome proliferator-activated receptor delta b
pparaa
ENSDARG00000031777 peroxisome proliferator-activated receptor alpha a
pparda
ENSDARG00000044525 peroxisome proliferator-activated receptor delta a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ppardbdr11_v1_chr8_+_23711842_237118420.835.4e-03Click!
ppardadr11_v1_chr22_+_997838_997838-0.835.9e-03Click!
pparaadr11_v1_chr4_-_18635005_18635005-0.491.8e-01Click!

Activity profile of pparaa+pparda+ppardb motif

Sorted Z-values of pparaa+pparda+ppardb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_999421 8.43 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr10_-_44027391 5.52 ENSDART00000145404
crybb1
crystallin, beta B1
chr25_+_21829777 4.70 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr13_-_37127970 3.77 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr19_+_40861853 3.07 ENSDART00000126470
zgc:85777
zgc:85777
chr11_-_6974022 3.06 ENSDART00000172851
COMP
si:ch211-43f4.1
chr13_+_28819768 2.89 ENSDART00000191401
ENSDART00000188895
ENSDART00000101653
CU639469.1

chr12_-_5120339 2.88 ENSDART00000168759
rbp4
retinol binding protein 4, plasma
chr14_-_48103207 2.75 ENSDART00000056712
etfdh
electron-transferring-flavoprotein dehydrogenase
chr12_-_5120175 2.75 ENSDART00000160729
rbp4
retinol binding protein 4, plasma
chr22_+_22888 2.74 ENSDART00000082471
mfap2
microfibril associated protein 2
chr11_+_11201096 2.66 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr1_+_25848231 2.65 ENSDART00000027973
fabp2
fatty acid binding protein 2, intestinal
chr21_-_19006631 2.46 ENSDART00000080269
ENSDART00000191682
pgam2
phosphoglycerate mutase 2 (muscle)
chr18_+_16744307 2.24 ENSDART00000179872
ENSDART00000133490
lyve1b
lymphatic vessel endothelial hyaluronic receptor 1b
chr6_+_60055168 2.14 ENSDART00000008752
pck1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr23_-_24488696 2.09 ENSDART00000155593
tmem82
transmembrane protein 82
chr5_+_36974931 2.09 ENSDART00000193063
gjd1a
gap junction protein delta 1a
chr17_+_12408188 2.01 ENSDART00000105218
khk
ketohexokinase
chr7_-_24046999 1.97 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr20_+_15015557 1.95 ENSDART00000039345
myoc
myocilin
chr23_-_45504991 1.92 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr13_+_829585 1.85 ENSDART00000029051
gsta.2
glutathione S-transferase, alpha tandem duplicate 2
chr9_-_1939232 1.83 ENSDART00000146131
hoxd3a
homeobox D3a
chr24_+_9590188 1.78 ENSDART00000137092
si:dkey-96n2.1
si:dkey-96n2.1
chr10_+_20128267 1.71 ENSDART00000064615
dmtn
dematin actin binding protein
chr13_+_28821841 1.67 ENSDART00000179900
CU639469.1

chr6_-_39764995 1.59 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr17_+_12408405 1.59 ENSDART00000154827
ENSDART00000048440
ENSDART00000156429
khk
ketohexokinase
chr25_+_5288665 1.57 ENSDART00000169540
CABZ01039861.1

chr10_-_17284055 1.51 ENSDART00000167464
GNAZ
G protein subunit alpha z
chr17_+_32374876 1.49 ENSDART00000183851
ywhaqb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr5_+_38200807 1.45 ENSDART00000100769
hsd20b2
hydroxysteroid (20-beta) dehydrogenase 2
chr21_+_26720803 1.40 ENSDART00000053797
slc3a2b
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr4_-_16451375 1.40 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr3_-_53486169 1.39 ENSDART00000115243
soul5
heme-binding protein soul5
chr1_+_40802454 1.33 ENSDART00000193568
cpz
carboxypeptidase Z
chr19_+_32158010 1.33 ENSDART00000005255
mrpl53
mitochondrial ribosomal protein L53
chr2_-_42960353 1.33 ENSDART00000098303
oc90
otoconin 90
chr22_+_38229321 1.30 ENSDART00000132670
ENSDART00000104504
si:ch211-284e20.8
si:ch211-284e20.8
chr3_-_58116314 1.29 ENSDART00000154901
si:ch211-256e16.6
si:ch211-256e16.6
chr6_-_39765546 1.26 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr17_+_450956 1.24 ENSDART00000183022
ENSDART00000171386
zgc:194887
zgc:194887
chr23_-_39636195 1.21 ENSDART00000144439
vwa1
von Willebrand factor A domain containing 1
chr16_-_50229193 1.19 ENSDART00000161782
ENSDART00000010081
etfb
electron-transfer-flavoprotein, beta polypeptide
chr11_+_24957858 1.08 ENSDART00000145647
sulf2a
sulfatase 2a
chr15_+_17030473 1.07 ENSDART00000129407
plin2
perilipin 2
chr5_+_38276582 1.07 ENSDART00000158532
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr20_+_43379029 1.06 ENSDART00000142486
ENSDART00000186486
unc93a
unc-93 homolog A
chr10_+_35417099 1.04 ENSDART00000063398
hhla2a.1
HERV-H LTR-associating 2a, tandem duplicate 1
chr19_+_2275019 1.01 ENSDART00000136138
itgb8
integrin, beta 8
chr20_+_54738210 0.98 ENSDART00000151399
pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr5_-_23362602 0.96 ENSDART00000137120
gria3a
glutamate receptor, ionotropic, AMPA 3a
chr7_+_69019851 0.94 ENSDART00000162891
CABZ01057488.1

chr20_-_34164278 0.92 ENSDART00000153128
hmcn1
hemicentin 1
chr20_-_52967878 0.92 ENSDART00000164460
gata4
GATA binding protein 4
chr24_+_81527 0.91 ENSDART00000192139
reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr17_-_20711735 0.90 ENSDART00000150056
ank3b
ankyrin 3b
chr8_-_20291922 0.86 ENSDART00000148304
myo1f
myosin IF
chr1_-_52292235 0.83 ENSDART00000132638
si:dkey-121b10.7
si:dkey-121b10.7
chr2_-_32551178 0.81 ENSDART00000145603
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr14_-_29826659 0.81 ENSDART00000138413
sorbs2b
sorbin and SH3 domain containing 2b
chr21_+_39941184 0.80 ENSDART00000133604
slc47a1
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr2_+_7213146 0.79 ENSDART00000191134
ENSDART00000146547
si:ch211-13f8.2
si:ch211-13f8.2
chr8_-_979735 0.78 ENSDART00000149612
znf366
zinc finger protein 366
chr17_+_30545895 0.74 ENSDART00000076739
nhsl1a
NHS-like 1a
chr3_+_32546499 0.72 ENSDART00000151739
pax10
paired box 10
chr20_-_38836161 0.71 ENSDART00000061358
si:dkey-221h15.4
si:dkey-221h15.4
chr3_+_58167288 0.70 ENSDART00000155874
ENSDART00000010395
uqcrc2a
ubiquinol-cytochrome c reductase core protein 2a
chr12_-_6033824 0.66 ENSDART00000131301
ENSDART00000139419
ENSDART00000032050
g6pca.1
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 1
chr15_-_12500938 0.64 ENSDART00000159627
scn4ba
sodium channel, voltage-gated, type IV, beta a
chr4_-_24031924 0.58 ENSDART00000017443
celf2
cugbp, Elav-like family member 2
chr18_-_48508585 0.55 ENSDART00000133364
kcnj1a.4
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr16_+_28601974 0.55 ENSDART00000018235
crot
carnitine O-octanoyltransferase
chr15_+_45640906 0.53 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr7_+_11459235 0.52 ENSDART00000159611
il16
interleukin 16
chr15_+_17031111 0.52 ENSDART00000175378
plin2
perilipin 2
chr15_+_17030941 0.51 ENSDART00000062069
plin2
perilipin 2
chr20_-_26937453 0.50 ENSDART00000139756
ftr97
finTRIM family, member 97
chr5_-_66301142 0.50 ENSDART00000067541
prlrb
prolactin receptor b
chr19_-_43552252 0.49 ENSDART00000138308
gpr186
G protein-coupled receptor 186
chr22_-_10774735 0.48 ENSDART00000081156
timm13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr5_-_30984271 0.46 ENSDART00000051392
spns3
spinster homolog 3 (Drosophila)
chr21_+_15704556 0.44 ENSDART00000024858
ENSDART00000146909
chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr17_-_12196865 0.43 ENSDART00000154694
kif28
kinesin family member 28
chr18_-_48517040 0.42 ENSDART00000143645
kcnj1a.3
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr16_+_28602423 0.41 ENSDART00000182350
crot
carnitine O-octanoyltransferase
chr9_+_32069989 0.41 ENSDART00000139540
si:dkey-83m22.7
si:dkey-83m22.7
chr24_+_2961098 0.41 ENSDART00000163760
ENSDART00000170835
eci2
enoyl-CoA delta isomerase 2
chr12_+_7491690 0.41 ENSDART00000152564
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr10_-_41400049 0.40 ENSDART00000009838
gpat4
glycerol-3-phosphate acyltransferase 4
chr23_+_36340520 0.40 ENSDART00000011201
copz1
coatomer protein complex, subunit zeta 1
chr5_+_43870389 0.39 ENSDART00000141002
zgc:112966
zgc:112966
chr7_-_38633867 0.39 ENSDART00000137424
c1qtnf4
C1q and TNF related 4
chr20_-_48604199 0.35 ENSDART00000161762
ENSDART00000170894
mgst3a
microsomal glutathione S-transferase 3a
chr18_-_3456117 0.35 ENSDART00000158508
myo7aa
myosin VIIAa
chr15_+_404891 0.35 ENSDART00000155682
nipsnap2
nipsnap homolog 2
chr5_-_69940868 0.33 ENSDART00000185924
ENSDART00000097357
ugt2a4
UDP glucuronosyltransferase 2 family, polypeptide A4
chr1_+_58353661 0.32 ENSDART00000140074
si:dkey-222h21.2
si:dkey-222h21.2
chr5_-_36549024 0.32 ENSDART00000097671
zgc:158432
zgc:158432
chr20_-_48604621 0.31 ENSDART00000161769
ENSDART00000157871
mgst3a
microsomal glutathione S-transferase 3a
chr12_-_44199316 0.30 ENSDART00000170378
si:ch73-329n5.1
si:ch73-329n5.1
chr23_+_44633858 0.30 ENSDART00000180728
si:ch73-265d7.2
si:ch73-265d7.2
chr17_-_12408109 0.29 ENSDART00000155509
ankef1b
ankyrin repeat and EF-hand domain containing 1b
chr4_+_60492313 0.29 ENSDART00000191043
ENSDART00000191631
si:dkey-211i20.2
si:dkey-211i20.2
chr4_+_67999732 0.28 ENSDART00000190597
si:ch211-133h13.1
si:ch211-133h13.1
chr23_-_16734009 0.25 ENSDART00000125449
si:ch211-224l10.4
si:ch211-224l10.4
chr16_-_30563129 0.23 ENSDART00000191716
lmna
lamin A
chr5_-_32890807 0.23 ENSDART00000007512
pole3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr10_+_45128375 0.23 ENSDART00000164805
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr7_+_23940933 0.22 ENSDART00000173628
si:dkey-183c6.7
si:dkey-183c6.7
chr5_-_30984010 0.22 ENSDART00000182367
spns3
spinster homolog 3 (Drosophila)
chr22_+_9239831 0.22 ENSDART00000133720
si:ch211-250k18.5
si:ch211-250k18.5
chr17_-_32370047 0.21 ENSDART00000145487
klf11b
Kruppel-like factor 11b
chr5_-_41860556 0.21 ENSDART00000140154
si:dkey-65b12.12
si:dkey-65b12.12
chr23_-_16737161 0.20 ENSDART00000132573
si:ch211-224l10.4
si:ch211-224l10.4
chr15_+_31820536 0.19 ENSDART00000045921
frya
furry homolog a (Drosophila)
chr8_-_8698607 0.19 ENSDART00000046712
zgc:86609
zgc:86609
chr16_-_29480335 0.17 ENSDART00000148930
lingo4b
leucine rich repeat and Ig domain containing 4b
chr18_+_31410652 0.17 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr4_-_20243021 0.16 ENSDART00000048023
cacna2d4a
calcium channel, voltage-dependent, alpha 2/delta subunit 4a
chr22_+_18469004 0.16 ENSDART00000061430
cilp2
cartilage intermediate layer protein 2
chr19_+_20274944 0.16 ENSDART00000151237
oxnad1
oxidoreductase NAD-binding domain containing 1
chr6_-_30863046 0.15 ENSDART00000155330
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr1_+_58442694 0.14 ENSDART00000160897
zgc:194906
zgc:194906
chr4_+_75577480 0.12 ENSDART00000188196
si:ch211-227e10.1
si:ch211-227e10.1
chr25_-_19420949 0.11 ENSDART00000181338
map1ab
microtubule-associated protein 1Ab
chr1_-_17797802 0.10 ENSDART00000041215
sorbs2a
sorbin and SH3 domain containing 2a
chr22_+_9069081 0.09 ENSDART00000187842
BX248395.1

chr13_-_31878263 0.09 ENSDART00000180411
syt14a
synaptotagmin XIVa
chr11_+_30981777 0.09 ENSDART00000148949
cacna1ab
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr19_+_7043634 0.08 ENSDART00000133954
mhc1uka
major histocompatibility complex class I UKA
chr22_+_9287929 0.06 ENSDART00000193522
si:ch211-250k18.7
si:ch211-250k18.7
chr7_-_6279138 0.05 ENSDART00000173299
si:ch211-220f21.2
si:ch211-220f21.2
chr5_-_41875834 0.05 ENSDART00000133592
si:dkey-65b12.10
si:dkey-65b12.10
chr10_+_11265387 0.05 ENSDART00000038888
hsdl2
hydroxysteroid dehydrogenase like 2
chr4_-_36032177 0.04 ENSDART00000170143
zgc:174180
zgc:174180
chr22_+_9114416 0.04 ENSDART00000190169
nlrp15
NACHT, LRR and PYD domains-containing protein 15
chr4_-_991043 0.03 ENSDART00000184706
naga
N-acetylgalactosaminidase, alpha
chr5_-_50600512 0.03 ENSDART00000190318
mctp1a
multiple C2 domains, transmembrane 1a
chr12_-_684200 0.02 ENSDART00000152122
si:ch211-176g6.2
si:ch211-176g6.2
chr1_+_57050899 0.02 ENSDART00000152601
si:ch211-1f22.14
si:ch211-1f22.14
chr7_+_17356482 0.02 ENSDART00000063629
nitr3r.1l
novel immune-type receptor 3, related 1-like
chr2_-_56649883 0.01 ENSDART00000191786
gpx4b
glutathione peroxidase 4b
chr18_+_27926839 0.01 ENSDART00000191835
hipk3b
homeodomain interacting protein kinase 3b
chr18_+_15182965 0.00 ENSDART00000137018
si:ch73-62b13.1
si:ch73-62b13.1

Network of associatons between targets according to the STRING database.

First level regulatory network of pparaa+pparda+ppardb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0009750 response to fructose(GO:0009750)
0.8 5.6 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.5 2.1 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.4 4.7 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.3 1.9 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.3 0.9 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.3 2.9 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 2.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 0.9 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 3.9 GO:0006949 syncytium formation by plasma membrane fusion(GO:0000768) syncytium formation(GO:0006949)
0.1 0.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.9 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.3 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 1.0 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.8 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 1.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 1.5 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.1 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.1 1.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 11.1 GO:0033993 response to lipid(GO:0033993)
0.0 0.5 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 2.7 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.2 GO:0090342 regulation of cell aging(GO:0090342)
0.0 4.9 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.0 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.5 GO:0050927 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 2.7 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 0.9 GO:0071711 basement membrane organization(GO:0071711)
0.0 2.1 GO:0007416 synapse assembly(GO:0007416)
0.0 0.4 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 2.7 GO:0006936 muscle contraction(GO:0006936)
0.0 1.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.5 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005592 collagen type XI trimer(GO:0005592)
0.3 2.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.9 GO:1990909 Wnt signalosome(GO:1990909)
0.2 2.1 GO:0005922 connexon complex(GO:0005922)
0.2 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 2.7 GO:0031430 M band(GO:0031430)
0.1 1.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 2.8 GO:0005811 lipid particle(GO:0005811)
0.1 0.8 GO:0071564 npBAF complex(GO:0071564)
0.1 2.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.7 GO:0044420 extracellular matrix component(GO:0044420)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.0 GO:0008305 integrin complex(GO:0008305)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.5 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.8 5.6 GO:0034632 retinol transporter activity(GO:0034632)
0.7 11.1 GO:0005504 fatty acid binding(GO:0005504)
0.5 2.5 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.4 4.7 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 2.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.8 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 1.0 GO:0016415 octanoyltransferase activity(GO:0016415)
0.2 2.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 2.1 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 3.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 0.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 2.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.1 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 5.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.5 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.1 1.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.1 GO:0030145 manganese ion binding(GO:0030145)
0.1 1.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.8 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 1.2 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 8.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 3.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 3.6 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions