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PRJNA195909:zebrafish embryo and larva development
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Results for ptf1a+si:dkey-34f9.3
Z-value: 1.29
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Transcription factors associated with ptf1a+si:dkey-34f9.3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ptf1a | dr11_v1_chr2_+_29710857_29710857 | 0.05 | 9.0e-01 | Click! |
| si:dkey-34f9.3 | dr11_v1_chr9_+_45789887_45789887 | 0.01 | 9.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_6172154 Show fit | 2.20 |
ENSDART00000185434
|
apobec1 complementation factor |
|
| chr21_-_25601648 Show fit | 2.00 |
ENSDART00000042578
|
EGF containing fibulin extracellular matrix protein 2b |
|
| chr24_-_33756003 Show fit | 1.93 |
ENSDART00000079283
|
transmembrane protein with EGF-like and two follistatin-like domains 1b |
|
| chr16_-_46572834 Show fit | 1.88 |
ENSDART00000115248
|
zgc:174938 |
|
| chr15_-_46828958 Show fit | 1.87 |
ENSDART00000045110
|
chordin |
|
| chr16_-_46573211 Show fit | 1.77 |
ENSDART00000193392
|
zgc:174938 |
|
| chr17_-_11015878 Show fit | 1.72 |
ENSDART00000162249
|
dishevelled-binding antagonist of beta-catenin 1 |
|
| chr1_-_59407322 Show fit | 1.57 |
ENSDART00000161661
|
si:ch211-188p14.5 |
|
| chr10_-_15048781 Show fit | 1.50 |
ENSDART00000038401
ENSDART00000155674 |
si:ch211-95j8.2 |
|
| chr15_-_26636826 Show fit | 1.49 |
ENSDART00000087632
|
solute carrier family 47 (multidrug and toxin extrusion), member 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ptf1a+si:dkey-34f9.3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.2 | GO:0016556 | mRNA modification(GO:0016556) |
| 0.1 | 2.0 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.4 | 1.9 | GO:0010159 | specification of organ position(GO:0010159) |
| 0.3 | 1.7 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
| 0.0 | 1.6 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 0.5 | 1.4 | GO:0006601 | creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601) |
| 0.0 | 1.2 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
| 0.2 | 1.1 | GO:0055016 | hypochord development(GO:0055016) |
| 0.1 | 1.1 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 1.1 | GO:0051607 | defense response to virus(GO:0051607) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 0.0 | 1.1 | GO:0031228 | integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228) |
| 0.0 | 0.7 | GO:0097610 | cleavage furrow(GO:0032154) recycling endosome membrane(GO:0055038) cell surface furrow(GO:0097610) |
| 0.0 | 0.6 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.0 | 0.5 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.5 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 0.4 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.0 | 0.2 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.1 | 1.5 | GO:0042910 | xenobiotic transporter activity(GO:0042910) |
| 0.0 | 1.4 | GO:0016769 | transferase activity, transferring nitrogenous groups(GO:0016769) |
| 0.0 | 1.2 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.3 | 1.1 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.0 | 1.1 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.2 | 1.0 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.0 | 1.0 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 0.7 | GO:0043035 | chromatin insulator sequence binding(GO:0043035) |
| 0.0 | 0.7 | GO:0031267 | small GTPase binding(GO:0031267) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 1.7 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.5 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.4 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |
| 0.1 | 1.1 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 1.0 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.6 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.0 | 0.4 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.3 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |