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PRJNA195909:zebrafish embryo and larva development

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Results for rbpjb

Z-value: 2.37

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Transcription factors associated with rbpjb

Gene Symbol Gene ID Gene Info
rbpjb
ENSDARG00000052091 recombination signal binding protein for immunoglobulin kappa J region b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rbpjbdr11_v1_chr7_+_62080456_62080456-0.817.7e-03Click!

Activity profile of rbpjb motif

Sorted Z-values of rbpjb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_41981959 6.77 ENSDART00000055707
her15.1
hairy and enhancer of split-related 15, tandem duplicate 1
chr1_+_44442140 5.56 ENSDART00000190592
crybb1l2
crystallin, beta B1, like 2
chr7_+_31891110 5.36 ENSDART00000173883
mybpc3
myosin binding protein C, cardiac
chr19_-_31802296 5.26 ENSDART00000103640
hey1
hes-related family bHLH transcription factor with YRPW motif 1
chr9_-_22092089 5.07 ENSDART00000101928
crygm2d13
crystallin, gamma M2d13
chr24_-_37877743 4.89 ENSDART00000105658
tmem204
transmembrane protein 204
chr9_-_22205682 4.37 ENSDART00000101869
crygm2d12
crystallin, gamma M2d12
chr17_-_25326685 4.36 ENSDART00000082327
pabpc4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr19_+_42609132 4.18 ENSDART00000010104
crtap
cartilage associated protein
chr23_-_23401305 4.03 ENSDART00000078936
her9
hairy-related 9
chr3_+_26081343 4.01 ENSDART00000134647
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr14_+_38786298 3.92 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr17_-_25326296 3.89 ENSDART00000168822
pabpc4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr3_+_23677351 3.83 ENSDART00000023674
hoxb9a
homeobox B9a
chr9_-_22147567 3.78 ENSDART00000110941
crygm2d14
crystallin, gamma M2d14
chr19_-_5254699 3.62 ENSDART00000081951
stx1b
syntaxin 1B
chr23_-_31372639 3.54 ENSDART00000179908
ENSDART00000135620
ENSDART00000053367
hmgn3
high mobility group nucleosomal binding domain 3
chr24_-_26310854 3.54 ENSDART00000080113
apodb
apolipoprotein Db
chr25_-_23526058 3.53 ENSDART00000191331
ENSDART00000062930
phlda2
pleckstrin homology-like domain, family A, member 2
chr1_-_45633955 3.49 ENSDART00000044057
sept3
septin 3
chr23_-_21471022 3.21 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr9_-_22076368 3.19 ENSDART00000128486
crygm2a
crystallin, gamma M2a
chr15_+_7176182 3.17 ENSDART00000101578
her8.2
hairy-related 8.2
chr19_+_19767567 3.10 ENSDART00000169074
hoxa3a
homeobox A3a
chr16_-_31717851 2.98 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr4_-_20043484 2.89 ENSDART00000167780
zgc:193726
zgc:193726
chr5_-_28679135 2.88 ENSDART00000193585
tnc
tenascin C
chr2_-_32769759 2.86 ENSDART00000178951
bfsp2
beaded filament structural protein 2, phakinin
chr7_-_26436436 2.83 ENSDART00000019035
ENSDART00000123395
her8a
hairy-related 8a
chr13_+_30804367 2.81 ENSDART00000053946
cxcl12a
chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
chr9_-_22345500 2.67 ENSDART00000101802
crygm2f
crystallin, gamma M2f
chr6_+_3680651 2.64 ENSDART00000013588
klhl41b
kelch-like family member 41b
chr3_-_36839115 2.55 ENSDART00000154553
ramp2
receptor (G protein-coupled) activity modifying protein 2
chr7_+_36041509 2.49 ENSDART00000162850
irx3a
iroquois homeobox 3a
chr22_+_24715282 2.48 ENSDART00000088027
ENSDART00000189054
ENSDART00000140430
ssx2ipb
synovial sarcoma, X breakpoint 2 interacting protein b
chr16_+_9762261 2.46 ENSDART00000020654
psmd4b
proteasome 26S subunit, non-ATPase 4b
chr16_-_31718013 2.45 ENSDART00000190716
rbp5
retinol binding protein 1a, cellular
chr1_+_12763920 2.43 ENSDART00000189465
pcdh10a
protocadherin 10a
chr9_-_22023061 2.41 ENSDART00000101952
crygm2c
crystallin, gamma M2c
chr23_-_21446985 2.31 ENSDART00000044080
her12
hairy-related 12
chr8_-_13010011 2.30 ENSDART00000140969
dennd2da
DENN/MADD domain containing 2Da
chr5_-_56513825 2.23 ENSDART00000024207
tbx2a
T-box 2a
chr6_+_45932276 2.23 ENSDART00000103491
rbp7b
retinol binding protein 7b, cellular
chr7_+_46252993 2.19 ENSDART00000167149
znf536
zinc finger protein 536
chr24_-_37877554 2.10 ENSDART00000132219
tmem204
transmembrane protein 204
chr4_-_9722568 2.10 ENSDART00000067190
tspan9b
tetraspanin 9b
chr4_-_5302162 2.08 ENSDART00000177099
SNAP91 (1 of many)
si:ch211-214j24.9
chr5_+_10015002 2.08 ENSDART00000140570
slc2a11b
solute carrier family 2 (facilitated glucose transporter), member 11b
chr5_-_66028714 2.07 ENSDART00000022625
ENSDART00000164228
nrarpb
NOTCH regulated ankyrin repeat protein b
chr5_+_9348284 2.04 ENSDART00000149417
tal2
T-cell acute lymphocytic leukemia 2
chr16_+_26449615 2.04 ENSDART00000039746
epb41b
erythrocyte membrane protein band 4.1b
chr11_-_11518469 2.04 ENSDART00000104254
krt15
keratin 15
chr17_-_6730247 1.99 ENSDART00000031091
vsnl1b
visinin-like 1b
chr23_+_31405497 1.99 ENSDART00000053546
sh3bgrl2
SH3 domain binding glutamate-rich protein like 2
chr10_+_22782522 1.95 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
si:ch211-237l4.6
chr2_+_35728033 1.95 ENSDART00000002094
ankrd45
ankyrin repeat domain 45
chr2_-_9646857 1.93 ENSDART00000056901
zgc:153615
zgc:153615
chr5_+_39563301 1.92 ENSDART00000131245
ENSDART00000097872
si:ch211-57h10.1
si:ch211-57h10.1
chr14_+_4151379 1.91 ENSDART00000160431
dhrs13l1
dehydrogenase/reductase (SDR family) member 13 like 1
chr4_+_21741228 1.90 ENSDART00000112035
ENSDART00000127664
myf5
myogenic factor 5
chr15_-_37846047 1.90 ENSDART00000184837
hsc70
heat shock cognate 70
chr4_-_9891874 1.90 ENSDART00000067193
adm2a
adrenomedullin 2a
chr2_+_2110271 1.88 ENSDART00000148460
dspa
desmoplakin a
chr20_+_6590220 1.85 ENSDART00000136567
tns3.2
tensin 3, tandem duplicate 2
chr19_+_44009473 1.84 ENSDART00000151004
nkd3
naked cuticle homolog 3
chr22_+_5727753 1.84 ENSDART00000063484
si:dkey-222f2.1
si:dkey-222f2.1
chr14_+_35806605 1.79 ENSDART00000173093
gria2b
glutamate receptor, ionotropic, AMPA 2b
chr10_+_25982212 1.79 ENSDART00000128292
ENSDART00000108808
frem2a
Fras1 related extracellular matrix protein 2a
chr5_-_47727819 1.75 ENSDART00000165249
cox7c
cytochrome c oxidase, subunit VIIc
chr6_-_14139503 1.71 ENSDART00000089577
cacnb4b
calcium channel, voltage-dependent, beta 4b subunit
chr5_-_33287691 1.68 ENSDART00000004238
rpl7a
ribosomal protein L7a
chr13_-_36579086 1.66 ENSDART00000146671
lgals3a
lectin, galactoside binding soluble 3a
chr7_+_38445938 1.64 ENSDART00000173467
cep89
centrosomal protein 89
chr3_+_23092762 1.62 ENSDART00000142884
ENSDART00000024136
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr3_+_37574885 1.62 ENSDART00000055225
wnt9b
wingless-type MMTV integration site family, member 9B
chr5_+_15202495 1.52 ENSDART00000144915
tbx1
T-box 1
chr9_+_38684871 1.45 ENSDART00000147938
ENSDART00000004462
heg1
heart development protein with EGF-like domains 1
chr4_+_19535946 1.43 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
lrrc4.1
leucine rich repeat containing 4.1
chr20_-_47731768 1.41 ENSDART00000031167
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr13_-_27916439 1.40 ENSDART00000139081
ENSDART00000087097
ogfrl1
opioid growth factor receptor-like 1
chr3_+_41917499 1.39 ENSDART00000028673
lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_3696038 1.37 ENSDART00000150499
ENSDART00000136906
ENSDART00000164152
ENSDART00000128514
ENSDART00000108964
egfra
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr8_+_23009662 1.35 ENSDART00000030885
uckl1a
uridine-cytidine kinase 1-like 1a
chr3_-_29869120 1.34 ENSDART00000138327
rpl3
ribosomal protein L3
chr3_-_28665291 1.32 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr21_-_5881344 1.32 ENSDART00000009241
rpl35
ribosomal protein L35
chr4_-_8014463 1.32 ENSDART00000036153
ccdc3a
coiled-coil domain containing 3a
chr13_+_33246150 1.30 ENSDART00000136356
ENSDART00000132834
ENSDART00000144379
ENSDART00000131985
ENSDART00000148368
ENSDART00000035940
ENSDART00000141912
ndufaf1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
chr5_-_2112030 1.29 ENSDART00000091932
gusb
glucuronidase, beta
chr21_-_5799122 1.27 ENSDART00000129351
ENSDART00000151202
ccni
cyclin I
chr5_-_66028371 1.27 ENSDART00000183012
nrarpb
NOTCH regulated ankyrin repeat protein b
chr22_-_11729350 1.24 ENSDART00000105813
krt222
keratin 222
chr7_-_33960170 1.23 ENSDART00000180766
skor1a
SKI family transcriptional corepressor 1a
chr23_-_31346319 1.22 ENSDART00000008401
ENSDART00000138106
phip
pleckstrin homology domain interacting protein
chr7_+_39634873 1.22 ENSDART00000114774
ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr16_+_36671064 1.22 ENSDART00000109703
col6a4a
collagen, type VI, alpha 4a
chr21_-_43485351 1.19 ENSDART00000151597
ankrd46a
ankyrin repeat domain 46a
chr16_-_27628994 1.17 ENSDART00000157407
nacad
NAC alpha domain containing
chr10_+_17026870 1.14 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr17_+_24851951 1.12 ENSDART00000180746
cx35.4
connexin 35.4
chr19_-_32641725 1.11 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr16_+_46492994 1.10 ENSDART00000134734
rpz5
rapunzel 5
chr16_+_5579744 1.10 ENSDART00000147973
macf1b
microtubule-actin crosslinking factor 1 b
chr2_+_32835679 1.08 ENSDART00000132767
pxdc1a
PX domain containing 1a
chr22_-_30881738 1.08 ENSDART00000059965
si:dkey-49n23.1
si:dkey-49n23.1
chr7_+_27834130 1.08 ENSDART00000052656
rras2
RAS related 2
chr19_-_7540821 1.07 ENSDART00000143958
lix1l
limb and CNS expressed 1 like
chr9_-_52962521 1.06 ENSDART00000170419
CU855885.1

chr19_+_48018464 1.05 ENSDART00000172307
ENSDART00000163848
UBE2M
si:ch1073-205c8.3
chr11_-_7320211 1.04 ENSDART00000091664
apc2
adenomatosis polyposis coli 2
chr5_+_46424437 1.04 ENSDART00000186511
vcana
versican a
chr10_-_10864331 1.04 ENSDART00000122657
nrarpa
NOTCH regulated ankyrin repeat protein a
chr3_+_59051503 1.04 ENSDART00000160767
rasd4
rasd family member 4
chr25_+_6186823 1.03 ENSDART00000153526
oaz2a
ornithine decarboxylase antizyme 2a
chr4_-_25215968 1.03 ENSDART00000066932
ENSDART00000066933
itih2
inter-alpha-trypsin inhibitor heavy chain 2
chr6_-_36552844 1.02 ENSDART00000023613
her6
hairy-related 6
chr13_-_40398556 1.00 ENSDART00000191921
nkx3.3
NK3 homeobox 3
chr14_+_41887070 1.00 ENSDART00000173264
slc7a11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr10_-_10863936 0.99 ENSDART00000180568
nrarpa
NOTCH regulated ankyrin repeat protein a
chr25_+_10793478 0.97 ENSDART00000058339
ENSDART00000134923
ap3s2
adaptor-related protein complex 3, sigma 2 subunit
chr11_+_13159988 0.97 ENSDART00000064176
mob3c
MOB kinase activator 3C
chr5_-_37252111 0.96 ENSDART00000185110
lrch2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr8_+_48491387 0.95 ENSDART00000086053
PRDM16
si:ch211-263k4.2
chr20_+_39283849 0.94 ENSDART00000002481
ENSDART00000146683
scara3
scavenger receptor class A, member 3
chr16_-_42523744 0.94 ENSDART00000017185
tbx20
T-box 20
chr5_-_22082918 0.92 ENSDART00000020908
zc4h2
zinc finger, C4H2 domain containing
chr17_+_6956696 0.90 ENSDART00000171368
zgc:172341
zgc:172341
chr25_+_3525494 0.86 ENSDART00000169775
RAB19 (1 of many)
RAB19, member RAS oncogene family
chr22_+_12431608 0.85 ENSDART00000108609
rnd3a
Rho family GTPase 3a
chr20_-_26536581 0.85 ENSDART00000181810
stx11b.2
syntaxin 11b, tandem duplicate 2
chr8_-_41273768 0.83 ENSDART00000108518
rnf10
ring finger protein 10
chr9_-_3671911 0.82 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr7_-_40738774 0.80 ENSDART00000084179
rnf32
ring finger protein 32
chr19_+_48018802 0.80 ENSDART00000161339
ENSDART00000166978
UBE2M
si:ch1073-205c8.3
chr8_+_48848200 0.79 ENSDART00000130673
tp73
tumor protein p73
chr8_-_41273461 0.78 ENSDART00000190598
rnf10
ring finger protein 10
chr7_+_17229282 0.77 ENSDART00000097982
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr25_+_21178033 0.77 ENSDART00000041169
erc1a
ELKS/RAB6-interacting/CAST family member 1a
chr15_+_5321612 0.76 ENSDART00000174345
or113-1
odorant receptor, family A, subfamily 113, member 1
chr10_-_4375190 0.76 ENSDART00000016102
CABZ01073795.1

chr10_+_1668106 0.76 ENSDART00000142278
sgsm1b
small G protein signaling modulator 1b
chr14_+_40685469 0.75 ENSDART00000172839
tnmd
tenomodulin
chr1_-_51720633 0.75 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr11_-_29563437 0.73 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr9_-_7089303 0.72 ENSDART00000146609
coa5
cytochrome C oxidase assembly factor 5
chr1_-_56363108 0.71 ENSDART00000021878
gcgrb
glucagon receptor b
chr8_-_15150131 0.70 ENSDART00000138253
bcar3
BCAR3, NSP family adaptor protein
chr17_-_20287530 0.66 ENSDART00000078703
ENSDART00000191289
add3b
adducin 3 (gamma) b
chr18_-_6943577 0.63 ENSDART00000132399
si:dkey-266m15.6
si:dkey-266m15.6
chr24_+_33622769 0.63 ENSDART00000079342
dnah5l
dynein, axonemal, heavy chain 5 like
chr25_+_10830269 0.63 ENSDART00000175736
si:ch211-147g22.5
si:ch211-147g22.5
chr24_-_6375774 0.62 ENSDART00000013294
anxa13
annexin A13
chr9_+_7358749 0.61 ENSDART00000081660
ihha
Indian hedgehog homolog a
chr23_+_32011768 0.61 ENSDART00000053509
plagx
pleiomorphic adenoma gene X
chr25_+_35304903 0.60 ENSDART00000034313
ENSDART00000187659
gas2a
growth arrest-specific 2a
chr16_-_27640995 0.59 ENSDART00000019658
nacad
NAC alpha domain containing
chr14_-_2213660 0.58 ENSDART00000162537
pcdh2ab3
protocadherin 2 alpha b 3
chr3_-_27784457 0.58 ENSDART00000019098
dnase1
deoxyribonuclease I
chr3_+_27722355 0.56 ENSDART00000132761
arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr5_-_57361594 0.56 ENSDART00000112793
cdc26
cell division cycle 26 homolog
chr16_-_17300030 0.56 ENSDART00000149267
kel
Kell blood group, metallo-endopeptidase
chr9_-_56399699 0.55 ENSDART00000170281
rab3gap1
RAB3 GTPase activating protein subunit 1
chr2_-_44746723 0.55 ENSDART00000041806
acsm3
acyl-CoA synthetase medium chain family member 3
chr16_-_40727455 0.55 ENSDART00000162331
si:dkey-22o22.2
si:dkey-22o22.2
chr5_+_9360394 0.54 ENSDART00000124642
FP236810.2

chr15_+_5339056 0.53 ENSDART00000174319
CABZ01018874.2

chr7_+_19424857 0.51 ENSDART00000173674
si:ch211-212k18.6
si:ch211-212k18.6
chr7_-_71837213 0.50 ENSDART00000168645
ENSDART00000160512
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr14_-_33521071 0.50 ENSDART00000052789
c1galt1c1
C1GALT1-specific chaperone 1
chr5_+_9377005 0.49 ENSDART00000124924
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr1_-_38538284 0.49 ENSDART00000009777
glra3
glycine receptor, alpha 3
chr10_+_3507861 0.48 ENSDART00000092684
rph3aa
rabphilin 3A homolog (mouse), a
chr23_-_36003441 0.48 ENSDART00000164699
calcoco1a
calcium binding and coiled-coil domain 1a
chr22_-_26834043 0.48 ENSDART00000087202
si:dkey-44g23.5
si:dkey-44g23.5
chr18_+_12655766 0.46 ENSDART00000144246
tbxas1
thromboxane A synthase 1 (platelet)
chr21_+_20549395 0.46 ENSDART00000181633
efna5a
ephrin-A5a
chr1_+_41886830 0.45 ENSDART00000185887
ENSDART00000084735
si:dkey-37g12.1
si:dkey-37g12.1
chr23_+_26039524 0.45 ENSDART00000142851
itih6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr20_-_15090862 0.44 ENSDART00000063892
ENSDART00000122592
si:dkey-239i20.2
si:dkey-239i20.2
chr5_-_25072607 0.44 ENSDART00000145061
pnpla7b
patatin-like phospholipase domain containing 7b
chr1_+_32528097 0.44 ENSDART00000128317
nlgn4a
neuroligin 4a
chr9_+_29589790 0.43 ENSDART00000140388
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr13_-_33654931 0.43 ENSDART00000020350
snx5
sorting nexin 5
chr5_+_9382301 0.41 ENSDART00000124017
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr9_-_22355391 0.40 ENSDART00000009115
crygm3
crystallin, gamma M3
chr5_+_38837429 0.39 ENSDART00000160236
fras1
Fraser extracellular matrix complex subunit 1
chr18_-_21177674 0.39 ENSDART00000060175
si:dkey-12e7.4
si:dkey-12e7.4
chr17_+_35362851 0.39 ENSDART00000137659
cmpk2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr2_+_6734108 0.38 ENSDART00000112227
brinp3b
bone morphogenetic protein/retinoic acid inducible neural-specific 3b
chr22_+_30335936 0.38 ENSDART00000059923
mxi1
max interactor 1, dimerization protein
chr10_+_9195190 0.37 ENSDART00000136364
antxr2b
anthrax toxin receptor 2b
chr15_-_21702317 0.36 ENSDART00000155824
IL4I1
si:dkey-40g16.6
chr15_+_29362714 0.34 ENSDART00000099916
ENSDART00000126196
gucy2f
guanylate cyclase 2F, retinal
chr17_+_49081828 0.34 ENSDART00000156492
tiam2a
T cell lymphoma invasion and metastasis 2a
chr14_+_30762131 0.32 ENSDART00000145039
si:ch211-145o7.3
si:ch211-145o7.3
chr12_+_41991635 0.31 ENSDART00000186161
ENSDART00000192510
TCERG1L
transcription elongation regulator 1 like
chr6_+_72040 0.30 ENSDART00000122957
crygm4
crystallin, gamma M4
chr21_+_34976600 0.30 ENSDART00000191672
ENSDART00000139635
rbm11
RNA binding motif protein 11
chr11_+_6159595 0.30 ENSDART00000178367
slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr15_-_40065265 0.30 ENSDART00000063781
ENSDART00000142394
gpr55a
G protein-coupled receptor 55a

Network of associatons between targets according to the STRING database.

First level regulatory network of rbpjb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
1.1 5.4 GO:0003210 cardiac atrium formation(GO:0003210)
1.0 4.0 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
1.0 2.9 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.9 2.8 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.7 2.2 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.7 3.6 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.7 3.4 GO:0043282 pharyngeal muscle development(GO:0043282)
0.5 5.4 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.4 3.1 GO:0060017 parathyroid gland development(GO:0060017)
0.4 3.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.3 1.4 GO:0055016 hypochord development(GO:0055016)
0.3 1.0 GO:0003093 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.3 1.7 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677) positive regulation of calcium ion import(GO:0090280)
0.3 1.9 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.2 0.9 GO:0060043 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.2 27.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.2 1.6 GO:0031643 positive regulation of myelination(GO:0031643)
0.2 4.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 1.3 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.2 1.3 GO:0044211 CTP salvage(GO:0044211)
0.2 2.5 GO:0043248 proteasome assembly(GO:0043248)
0.2 2.6 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 2.4 GO:0097324 melanocyte migration(GO:0097324)
0.1 1.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 5.8 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 1.9 GO:0042026 protein refolding(GO:0042026)
0.1 0.5 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.7 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.6 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 1.0 GO:0021794 thalamus development(GO:0021794)
0.1 3.5 GO:0007568 aging(GO:0007568)
0.1 1.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 1.9 GO:0042574 retinal metabolic process(GO:0042574)
0.1 1.4 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 3.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 1.0 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.9 GO:0048665 neuron fate specification(GO:0048665)
0.1 1.9 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.7 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.2 GO:0034138 toll-like receptor 2 signaling pathway(GO:0034134) toll-like receptor 3 signaling pathway(GO:0034138)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.8 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 2.0 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 2.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 2.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 6.3 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.1 0.7 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 17.3 GO:0050767 regulation of neurogenesis(GO:0050767)
0.1 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.6 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 1.0 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 0.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.2 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 3.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.9 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 1.1 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.8 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 2.2 GO:0033334 fin morphogenesis(GO:0033334)
0.0 2.5 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 2.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.8 GO:0007050 cell cycle arrest(GO:0007050)
0.0 3.5 GO:0043068 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 1.3 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.9 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 1.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.8 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 1.8 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.0 GO:0003218 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)
0.0 1.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.7 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.3 GO:0007043 cell-cell junction assembly(GO:0007043)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0031673 H zone(GO:0031673)
0.3 1.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 8.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 1.7 GO:0001772 immunological synapse(GO:0001772)
0.2 0.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 4.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 2.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 1.8 GO:0045095 keratin filament(GO:0045095)
0.2 0.5 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.1 1.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.9 GO:0014704 intercalated disc(GO:0014704)
0.1 4.3 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.1 2.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 7.2 GO:0005882 intermediate filament(GO:0005882)
0.1 4.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.6 GO:0005814 centriole(GO:0005814)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0043204 perikaryon(GO:0043204)
0.0 3.6 GO:0005743 mitochondrial inner membrane(GO:0005743)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.5 5.4 GO:0016918 retinal binding(GO:0016918)
0.5 5.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 1.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 27.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.7 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.3 1.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 4.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 1.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 1.3 GO:0004849 uridine kinase activity(GO:0004849)
0.2 3.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 1.4 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.7 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.1 2.8 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 2.6 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 1.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.5 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 1.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 4.2 GO:0005518 collagen binding(GO:0005518)
0.1 0.7 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.9 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.2 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.6 GO:0005113 patched binding(GO:0005113)
0.1 4.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 2.1 GO:0019003 GDP binding(GO:0019003)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 6.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.4 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.8 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 1.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0016408 C-acyltransferase activity(GO:0016408)
0.0 3.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 2.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 18.5 GO:0046983 protein dimerization activity(GO:0046983)
0.0 1.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 3.5 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.0 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 9.6 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 2.0 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 2.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 3.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 4.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 4.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins