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PRJNA195909:zebrafish embryo and larva development

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Results for rxraa+rxrab+rxrba+rxrgb

Z-value: 0.69

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Transcription factors associated with rxraa+rxrab+rxrba+rxrgb

Gene Symbol Gene ID Gene Info
rxrgb
ENSDARG00000004697 retinoid X receptor, gamma b
rxrab
ENSDARG00000035127 retinoid x receptor, alpha b
rxraa
ENSDARG00000057737 retinoid X receptor, alpha a
rxrba
ENSDARG00000078954 retinoid x receptor, beta a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rxrbadr11_v1_chr19_-_7274844_7274844-0.761.7e-02Click!
rxrgbdr11_v1_chr20_+_33875256_338752560.665.2e-02Click!
rxraadr11_v1_chr21_+_17880511_178805110.412.7e-01Click!
rxrabdr11_v1_chr5_-_64511428_645114280.029.5e-01Click!

Activity profile of rxraa+rxrab+rxrba+rxrgb motif

Sorted Z-values of rxraa+rxrab+rxrba+rxrgb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_5120339 1.82 ENSDART00000168759
rbp4
retinol binding protein 4, plasma
chr10_-_44027391 1.76 ENSDART00000145404
crybb1
crystallin, beta B1
chr12_-_5120175 1.71 ENSDART00000160729
rbp4
retinol binding protein 4, plasma
chr8_+_999421 1.70 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr3_-_31804481 1.32 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr13_-_37127970 1.32 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr5_-_36837846 1.24 ENSDART00000032481
ckma
creatine kinase, muscle a
chr21_-_19006631 1.18 ENSDART00000080269
ENSDART00000191682
pgam2
phosphoglycerate mutase 2 (muscle)
chr8_+_31435452 1.16 ENSDART00000145282
selenop
selenoprotein P
chr1_+_25848231 1.04 ENSDART00000027973
fabp2
fatty acid binding protein 2, intestinal
chr5_-_65004791 1.03 ENSDART00000180023
ANXA1 (1 of many)
zgc:110283
chr19_+_40861853 1.03 ENSDART00000126470
zgc:85777
zgc:85777
chr9_+_32978302 1.02 ENSDART00000007630
nhlh2
nescient helix loop helix 2
chr22_-_17595310 1.00 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr2_+_42191592 0.99 ENSDART00000144716
cavin4a
caveolae associated protein 4a
chr11_+_30729745 0.99 ENSDART00000103270
slc22a7a
solute carrier family 22 (organic anion transporter), member 7a
chr25_+_21829777 0.91 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr13_+_28819768 0.90 ENSDART00000191401
ENSDART00000188895
ENSDART00000101653
CU639469.1

chr17_+_450956 0.89 ENSDART00000183022
ENSDART00000171386
zgc:194887
zgc:194887
chr11_-_6974022 0.85 ENSDART00000172851
COMP
si:ch211-43f4.1
chr18_-_12052132 0.84 ENSDART00000074361
zgc:110789
zgc:110789
chr7_+_71664624 0.81 ENSDART00000170273
emilin2b
elastin microfibril interfacer 2b
chr9_-_22158325 0.80 ENSDART00000114568
crygm2d16
crystallin, gamma M2d16
chr9_-_22158784 0.80 ENSDART00000167850
crygm2d14
crystallin, gamma M2d14
chr14_+_36246726 0.80 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr10_-_29903165 0.78 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr23_-_46040618 0.78 ENSDART00000161415
CABZ01080918.1

chr6_+_60055168 0.78 ENSDART00000008752
pck1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr6_-_40429411 0.78 ENSDART00000156005
ENSDART00000156357
si:dkey-28n18.9
si:dkey-28n18.9
chr18_+_16744307 0.77 ENSDART00000179872
ENSDART00000133490
lyve1b
lymphatic vessel endothelial hyaluronic receptor 1b
chr23_-_45504991 0.76 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr19_+_32166702 0.75 ENSDART00000021798
fabp11a
fatty acid binding protein 11a
chr10_+_43994471 0.74 ENSDART00000138242
ENSDART00000186359
cldn5b
claudin 5b
chr11_+_11201096 0.74 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr14_-_48103207 0.73 ENSDART00000056712
etfdh
electron-transferring-flavoprotein dehydrogenase
chr16_+_42830152 0.73 ENSDART00000159730
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr21_+_20771082 0.72 ENSDART00000079732
oxct1b
3-oxoacid CoA transferase 1b
chr13_+_829585 0.72 ENSDART00000029051
gsta.2
glutathione S-transferase, alpha tandem duplicate 2
chr15_+_19838458 0.70 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr2_-_39017838 0.69 ENSDART00000048838
rbp2b
retinol binding protein 2b, cellular
chr4_-_2545310 0.69 ENSDART00000150619
ENSDART00000140760
e2f7
E2F transcription factor 7
chr22_-_15587360 0.69 ENSDART00000142717
ENSDART00000138978
tpm4a
tropomyosin 4a
chr18_-_17415580 0.69 ENSDART00000150077
ENSDART00000100190
ces2
carboxylesterase 2 (intestine, liver)
chr6_+_1787160 0.67 ENSDART00000113505
myl9b
myosin, light chain 9b, regulatory
chr25_+_15647993 0.66 ENSDART00000186578
ENSDART00000031828
spon1b
spondin 1b
chr23_+_42434348 0.65 ENSDART00000161027
cyp2aa1
cytochrome P450, family 2, subfamily AA, polypeptide 1
chr16_+_42829735 0.63 ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr23_-_45705525 0.63 ENSDART00000148959
ednrab
endothelin receptor type Ab
chr20_+_572037 0.63 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
smyd2b
SET and MYND domain containing 2b
chr7_-_24046999 0.63 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr20_+_15015557 0.62 ENSDART00000039345
myoc
myocilin
chr9_+_53337974 0.61 ENSDART00000145138
dct
dopachrome tautomerase
chr9_-_22834860 0.60 ENSDART00000146486
neb
nebulin
chr5_-_34609337 0.60 ENSDART00000145792
hexb
hexosaminidase B (beta polypeptide)
chr2_+_48303142 0.60 ENSDART00000023040
hes6
hes family bHLH transcription factor 6
chr5_+_36974931 0.60 ENSDART00000193063
gjd1a
gap junction protein delta 1a
chr18_+_17611627 0.59 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr3_-_49566364 0.59 ENSDART00000161507
zgc:153426
zgc:153426
chr24_+_9590188 0.58 ENSDART00000137092
si:dkey-96n2.1
si:dkey-96n2.1
chr17_+_12408188 0.58 ENSDART00000105218
khk
ketohexokinase
chr23_+_32335871 0.58 ENSDART00000149698
slc39a5
solute carrier family 39 (zinc transporter), member 5
chr17_+_32374876 0.58 ENSDART00000183851
ywhaqb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr5_+_38276582 0.57 ENSDART00000158532
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr25_+_5288665 0.57 ENSDART00000169540
CABZ01039861.1

chr23_+_27068225 0.56 ENSDART00000054238
mipa
major intrinsic protein of lens fiber a
chr9_+_35077546 0.55 ENSDART00000142688
si:dkey-192g7.3
si:dkey-192g7.3
chr7_+_38897836 0.55 ENSDART00000024330
creb3l1
cAMP responsive element binding protein 3-like 1
chr10_+_31244619 0.54 ENSDART00000145562
ENSDART00000184412
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr5_+_8919698 0.54 ENSDART00000046440
agpat9l
1-acylglycerol-3-phosphate O-acyltransferase 9, like
chr9_-_1939232 0.54 ENSDART00000146131
hoxd3a
homeobox D3a
chr2_-_42960353 0.53 ENSDART00000098303
oc90
otoconin 90
chr8_-_7847921 0.51 ENSDART00000188094
zgc:113363
zgc:113363
chr10_+_20128267 0.50 ENSDART00000064615
dmtn
dematin actin binding protein
chr21_-_35832548 0.50 ENSDART00000180840
sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr22_+_38229321 0.49 ENSDART00000132670
ENSDART00000104504
si:ch211-284e20.8
si:ch211-284e20.8
chr11_+_24957858 0.49 ENSDART00000145647
sulf2a
sulfatase 2a
chr23_+_42336084 0.48 ENSDART00000158959
ENSDART00000161812
cyp2aa7
cyp2aa8
cytochrome P450, family 2, subfamily AA, polypeptide 7
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr25_+_25453221 0.48 ENSDART00000176822
rassf7a
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr21_+_29077509 0.48 ENSDART00000128561
ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr16_-_24612871 0.48 ENSDART00000155614
ENSDART00000154787
ENSDART00000155983
ENSDART00000156519
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr23_-_20309505 0.47 ENSDART00000130856
lamb2l
laminin, beta 2-like
chr16_+_54875530 0.47 ENSDART00000149795
nr0b2a
nuclear receptor subfamily 0, group B, member 2a
chr23_-_637347 0.46 ENSDART00000132175
l1camb
L1 cell adhesion molecule, paralog b
chr14_-_9522364 0.45 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr21_-_5879897 0.45 ENSDART00000184034
rpl35
ribosomal protein L35
chr19_+_10979983 0.44 ENSDART00000142975
si:ch1073-70f20.1
si:ch1073-70f20.1
chr3_-_25119839 0.44 ENSDART00000154724
chadla
chondroadherin-like a
chr2_+_52847049 0.43 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr20_-_26491567 0.43 ENSDART00000147154
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr5_-_1962500 0.43 ENSDART00000150163
rplp0
ribosomal protein, large, P0
chr16_-_38518270 0.42 ENSDART00000131899
rspo2
R-spondin 2
chr12_+_31673588 0.42 ENSDART00000152971
dnmbp
dynamin binding protein
chr15_-_20233105 0.42 ENSDART00000123910
ppp1r14ab
protein phosphatase 1, regulatory (inhibitor) subunit 14Ab
chr25_-_204019 0.42 ENSDART00000188440
ENSDART00000191735
FP236318.2

chr4_-_16451375 0.42 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr19_+_2275019 0.41 ENSDART00000136138
itgb8
integrin, beta 8
chr19_+_32158010 0.41 ENSDART00000005255
mrpl53
mitochondrial ribosomal protein L53
chr10_+_35417099 0.41 ENSDART00000063398
hhla2a.1
HERV-H LTR-associating 2a, tandem duplicate 1
chr6_-_11523987 0.41 ENSDART00000189363
gulp1b
GULP, engulfment adaptor PTB domain containing 1b
chr23_+_23119008 0.41 ENSDART00000132418
samd11
sterile alpha motif domain containing 11
chr23_-_15216654 0.40 ENSDART00000131649
sulf2b
sulfatase 2b
chr7_-_2090594 0.39 ENSDART00000183166
si:cabz01007802.1
si:cabz01007802.1
chr1_-_44933094 0.38 ENSDART00000147527
si:dkey-9i23.14
si:dkey-9i23.14
chr17_-_17948587 0.38 ENSDART00000090447
hhipl1
HHIP-like 1
chr1_+_23783349 0.38 ENSDART00000007531
slit2
slit homolog 2 (Drosophila)
chr5_-_65000312 0.37 ENSDART00000192893
ANXA1 (1 of many)
zgc:110283
chr13_+_50375800 0.37 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr15_-_35246742 0.37 ENSDART00000131479
mff
mitochondrial fission factor
chr17_+_12408405 0.36 ENSDART00000154827
ENSDART00000048440
ENSDART00000156429
khk
ketohexokinase
chr7_+_31838320 0.36 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
mybpc3
myosin binding protein C, cardiac
chr11_+_77526 0.35 ENSDART00000193521
CABZ01072242.1

chr24_+_81527 0.35 ENSDART00000192139
reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr23_-_28294763 0.35 ENSDART00000139537
znf385a
zinc finger protein 385A
chr18_-_34549721 0.34 ENSDART00000137101
ENSDART00000021880
ssr3
signal sequence receptor, gamma
chr22_-_23612854 0.34 ENSDART00000165885
cfhl5
complement factor H like 5
chr21_+_25236297 0.34 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr13_+_28735151 0.32 ENSDART00000150376
ldb1a
LIM domain binding 1a
chr4_+_38981587 0.32 ENSDART00000142713
si:dkey-66k12.3
si:dkey-66k12.3
chr22_-_20126230 0.32 ENSDART00000138688
creb3l3a
cAMP responsive element binding protein 3-like 3a
chr23_+_27912079 0.31 ENSDART00000171859
BX539336.1

chr12_-_46315898 0.31 ENSDART00000153138
si:ch211-226h7.3
si:ch211-226h7.3
chr12_+_21697540 0.31 ENSDART00000153412
pkd1b
polycystic kidney disease 1b
chr7_+_69019851 0.31 ENSDART00000162891
CABZ01057488.1

chr2_+_5620742 0.31 ENSDART00000028390
fgf12a
fibroblast growth factor 12a
chr25_+_31238606 0.30 ENSDART00000149439
tnni2a.2
troponin I type 2a (skeletal, fast), tandem duplicate 2
chr19_+_14921000 0.30 ENSDART00000144052
oprd1a
opioid receptor, delta 1a
chr20_+_43379029 0.30 ENSDART00000142486
ENSDART00000186486
unc93a
unc-93 homolog A
chr15_-_23206562 0.30 ENSDART00000110360
ccdc153
coiled-coil domain containing 153
chr16_+_31802203 0.30 ENSDART00000058739
ENSDART00000110834
wnt4b
wingless-type MMTV integration site family, member 4b
chr1_-_50590626 0.30 ENSDART00000146892
ENSDART00000022733
abcg2d
ATP-binding cassette, sub-family G (WHITE), member 2d
chr13_+_28821841 0.30 ENSDART00000179900
CU639469.1

chr3_-_18792492 0.29 ENSDART00000134208
ENSDART00000034373
hagh
hydroxyacylglutathione hydrolase
chr13_-_40726865 0.29 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr20_+_13175379 0.29 ENSDART00000025644
ppp2r5a
protein phosphatase 2, regulatory subunit B', alpha isoform
chr7_+_31871830 0.29 ENSDART00000139899
mybpc3
myosin binding protein C, cardiac
chr18_-_48492951 0.29 ENSDART00000146346
kcnj1a.6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr23_-_39636195 0.28 ENSDART00000144439
vwa1
von Willebrand factor A domain containing 1
chr20_+_54738210 0.28 ENSDART00000151399
pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr1_-_51720633 0.28 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr20_-_45807982 0.28 ENSDART00000074546
fermt1
fermitin family member 1
chr8_-_41264502 0.28 ENSDART00000133124
rnf10
ring finger protein 10
chr3_-_58116314 0.27 ENSDART00000154901
si:ch211-256e16.6
si:ch211-256e16.6
chr15_-_16884912 0.27 ENSDART00000062135
zgc:103681
zgc:103681
chr17_+_51906053 0.27 ENSDART00000159072
ENSDART00000056869
flvcr2a
feline leukemia virus subgroup C cellular receptor family, member 2a
chr10_-_35542071 0.27 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr14_-_28052474 0.27 ENSDART00000172948
ENSDART00000135337
TSC22D3 (1 of many)
zgc:64189
si:ch211-220e11.3
zgc:64189
chr23_-_46126444 0.26 ENSDART00000030004
CABZ01071903.1

chr20_+_13969414 0.26 ENSDART00000049864
rd3
retinal degeneration 3
chr15_+_19797918 0.26 ENSDART00000113314
si:ch211-229d2.5
si:ch211-229d2.5
chr18_-_46256560 0.26 ENSDART00000171375
si:dkey-244a7.1
si:dkey-244a7.1
chr15_+_40281693 0.25 ENSDART00000186565
gal3st2
galactose-3-O-sulfotransferase 2
chr12_-_6033824 0.25 ENSDART00000131301
ENSDART00000139419
ENSDART00000032050
g6pca.1
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 1
chr16_-_23800484 0.25 ENSDART00000139964
rps27.2
ribosomal protein S27, isoform 2
chr2_-_24289641 0.25 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myh7l
myosin heavy chain 7-like
chr10_-_17284055 0.24 ENSDART00000167464
GNAZ
G protein subunit alpha z
chr22_-_10774735 0.24 ENSDART00000081156
timm13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr23_+_2778813 0.24 ENSDART00000142621
top1
DNA topoisomerase I
chr24_-_18477672 0.24 ENSDART00000126928
ENSDART00000158393
si:dkey-73n8.3
si:dkey-73n8.3
chr1_-_50167792 0.24 ENSDART00000182993
BX537118.1

chr13_-_21701323 0.24 ENSDART00000164112
si:dkey-191g9.7
si:dkey-191g9.7
chr3_-_56541723 0.24 ENSDART00000156398
ENSDART00000050576
ENSDART00000184874
si:ch211-189a21.1
cyth1a
si:ch211-189a21.1
cytohesin 1a
chr18_+_31410652 0.24 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr17_+_53424415 0.23 ENSDART00000157022
slc9a1b
solute carrier family 9 member A1b
chr8_+_48491387 0.23 ENSDART00000086053
PRDM16
si:ch211-263k4.2
chr1_-_1627487 0.23 ENSDART00000166094
clic6
chloride intracellular channel 6
chr1_-_9641845 0.23 ENSDART00000121490
ENSDART00000159411
ugt5b2
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B2
UDP glucuronosyltransferase 5 family, polypeptide B3
chr12_+_22870372 0.23 ENSDART00000182264
ENSDART00000191789
ENSDART00000130594
ENSDART00000190433
afap1
actin filament associated protein 1
chr10_-_690072 0.23 ENSDART00000164871
ENSDART00000142833
glis3
GLIS family zinc finger 3
chr11_+_36989696 0.23 ENSDART00000045888
tkta
transketolase a
chr24_-_1341543 0.23 ENSDART00000169341
nrp1a
neuropilin 1a
chr23_+_43954809 0.23 ENSDART00000164080
corin
corin, serine peptidase
chr5_+_38200807 0.22 ENSDART00000100769
hsd20b2
hydroxysteroid (20-beta) dehydrogenase 2
chr13_+_844150 0.22 ENSDART00000058260
gsta.1
glutathione S-transferase, alpha tandem duplicate 1
chr23_+_8679216 0.22 ENSDART00000111368
rgs19
regulator of G protein signaling 19
chr11_-_42472941 0.22 ENSDART00000166624
arf4b
ADP-ribosylation factor 4b
chr20_-_38836161 0.21 ENSDART00000061358
si:dkey-221h15.4
si:dkey-221h15.4
chr16_-_50203058 0.21 ENSDART00000154570
vsig10l
V-set and immunoglobulin domain containing 10 like
chr18_-_48508585 0.21 ENSDART00000133364
kcnj1a.4
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr3_+_32553714 0.20 ENSDART00000165638
pax10
paired box 10
chr19_-_41213718 0.20 ENSDART00000077121
pdk4
pyruvate dehydrogenase kinase, isozyme 4
chr17_+_20173882 0.20 ENSDART00000155379
si:ch211-248a14.8
si:ch211-248a14.8
chr5_-_30491172 0.20 ENSDART00000138464
phldb1a
pleckstrin homology-like domain, family B, member 1a
chr5_+_37035978 0.20 ENSDART00000167418
nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr3_+_30968883 0.20 ENSDART00000085736
prf1.9
perforin 1.9
chr1_-_52292235 0.19 ENSDART00000132638
si:dkey-121b10.7
si:dkey-121b10.7
chr18_-_48517040 0.19 ENSDART00000143645
kcnj1a.3
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr20_-_34164278 0.19 ENSDART00000153128
hmcn1
hemicentin 1
chr9_+_17429170 0.19 ENSDART00000006256
zgc:101559
zgc:101559
chr8_-_20380750 0.19 ENSDART00000113910
adamts10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr22_-_15671525 0.19 ENSDART00000080286
si:ch1073-396h14.1
si:ch1073-396h14.1
chr21_+_15833222 0.19 ENSDART00000151161
si:dkeyp-87d8.8
si:dkeyp-87d8.8
chr25_+_3525494 0.19 ENSDART00000169775
RAB19 (1 of many)
RAB19, member RAS oncogene family
chr16_-_1503023 0.18 ENSDART00000036348
sim1a
single-minded family bHLH transcription factor 1a
chr4_+_57099307 0.18 ENSDART00000131654
si:ch211-238e22.2
si:ch211-238e22.2
chr2_+_3533458 0.18 ENSDART00000133007
gpt2l
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr6_-_48082525 0.18 ENSDART00000192049
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr20_-_49117438 0.18 ENSDART00000057700
naa20
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr8_-_979735 0.18 ENSDART00000149612
znf366
zinc finger protein 366
chr10_-_6454386 0.18 ENSDART00000168549
ca9
carbonic anhydrase IX
chr18_-_15771551 0.18 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
si:ch211-219a15.3

Network of associatons between targets according to the STRING database.

First level regulatory network of rxraa+rxrab+rxrba+rxrgb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.5 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.3 0.9 GO:0009750 response to fructose(GO:0009750)
0.2 0.6 GO:0055057 neuroblast division(GO:0055057) positive regulation of stem cell proliferation(GO:2000648)
0.2 0.6 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.2 0.8 GO:0019626 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.2 1.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 0.5 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.2 2.1 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.4 GO:0033335 anal fin development(GO:0033335)
0.1 0.7 GO:0032875 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.1 0.6 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.4 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.6 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 0.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.4 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.1 0.6 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.7 GO:0021885 forebrain cell migration(GO:0021885)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.3 GO:0044246 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.1 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.4 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 0.3 GO:0097037 heme export(GO:0097037)
0.1 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.6 GO:0006833 water transport(GO:0006833)
0.1 0.2 GO:0072020 proximal straight tubule development(GO:0072020)
0.1 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.5 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 0.7 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.2 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.6 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.0 1.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.5 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.8 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.4 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.3 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 1.3 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 1.4 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 3.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.5 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.6 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.1 GO:1990359 detoxification of zinc ion(GO:0010312) manganese ion homeostasis(GO:0055071) stress response to zinc ion(GO:1990359)
0.0 0.2 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.1 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.0 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.7 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.0 GO:0015893 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 1.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.6 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.0 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.5 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.5 GO:0034632 retinol transporter activity(GO:0034632)
0.2 0.7 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 1.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.2 1.2 GO:0008430 selenium binding(GO:0008430)
0.2 1.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 2.7 GO:0005504 fatty acid binding(GO:0005504)
0.2 2.1 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.7 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.3 GO:0038046 enkephalin receptor activity(GO:0038046)
0.1 0.3 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 0.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.7 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.6 GO:0015250 water channel activity(GO:0015250)
0.1 0.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 4.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.6 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.8 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0016415 octanoyltransferase activity(GO:0016415)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 1.0 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.0 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.6 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI