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PRJNA195909:zebrafish embryo and larva development

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Results for six4a+six4b

Z-value: 0.86

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Transcription factors associated with six4a+six4b

Gene Symbol Gene ID Gene Info
six4a
ENSDARG00000004695 SIX homeobox 4a
six4b
ENSDARG00000031983 SIX homeobox 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
six4bdr11_v1_chr20_+_20484827_20484827-0.915.8e-04Click!
six4adr11_v1_chr13_-_31647323_31647323-0.862.8e-03Click!

Activity profile of six4a+six4b motif

Sorted Z-values of six4a+six4b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_13472234 1.74 ENSDART00000114069
ENSDART00000132406
cnnm4b
cyclin and CBS domain divalent metal cation transport mediator 4b
chr22_+_25242322 1.52 ENSDART00000134628
si:ch211-226h8.8
si:ch211-226h8.8
chr22_+_25236888 1.47 ENSDART00000037286
zgc:172218
zgc:172218
chr15_-_35126332 1.45 ENSDART00000007636
zgc:55413
zgc:55413
chr9_+_8396755 1.31 ENSDART00000043067
zgc:171776
zgc:171776
chr22_+_25236657 1.28 ENSDART00000138012
zgc:172218
zgc:172218
chr1_-_6085750 1.18 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr7_-_54217547 1.15 ENSDART00000162777
ENSDART00000188268
ENSDART00000165875
csnk1g1
casein kinase 1, gamma 1
chr18_+_27511976 1.12 ENSDART00000132017
ENSDART00000140781
tp53i11b
tumor protein p53 inducible protein 11b
chr25_+_5604512 1.09 ENSDART00000042781
plxnb2b
plexin b2b
chr16_+_50755133 1.07 ENSDART00000029283
IGLON5
zgc:110372
chr3_-_54607166 1.06 ENSDART00000021977
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr19_-_6083761 0.96 ENSDART00000151185
ENSDART00000143941
gsk3aa
glycogen synthase kinase 3 alpha a
chr7_+_48297842 0.92 ENSDART00000052123
slc25a44b
solute carrier family 25, member 44 b
chr19_-_10330778 0.88 ENSDART00000081465
ENSDART00000136653
ENSDART00000171232
ccdc106b
coiled-coil domain containing 106b
chr21_+_34167178 0.83 ENSDART00000158308
trpc5b
transient receptor potential cation channel, subfamily C, member 5b
chr5_-_57723929 0.81 ENSDART00000144237
gig2p
grass carp reovirus (GCRV)-induced gene 2p
chr7_-_60351537 0.78 ENSDART00000159875
plcb3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr9_+_2041535 0.76 ENSDART00000093187
lnpa
limb and neural patterns a
chr2_-_30770736 0.69 ENSDART00000131230
rgs20
regulator of G protein signaling 20
chr13_-_39399967 0.66 ENSDART00000190791
ENSDART00000136267
slc35f3b
solute carrier family 35, member F3b
chr12_+_1592146 0.66 ENSDART00000184575
ENSDART00000192902
SLC39A11
solute carrier family 39 member 11
chr2_+_50626476 0.64 ENSDART00000018150
neurod6b
neuronal differentiation 6b
chr6_-_3978919 0.63 ENSDART00000167753
slc25a12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr13_-_14269626 0.62 ENSDART00000079176
gfra4a
GDNF family receptor alpha 4a
chr23_-_7125494 0.62 ENSDART00000111929
slco4a1
solute carrier organic anion transporter family, member 4A1
chr16_-_46567344 0.61 ENSDART00000127721
si:dkey-152b24.7
si:dkey-152b24.7
chr7_+_38770167 0.61 ENSDART00000190827
arhgap1
Rho GTPase activating protein 1
chr20_-_51831657 0.59 ENSDART00000165076
mia3
melanoma inhibitory activity family, member 3
chr18_-_12416019 0.59 ENSDART00000144799
si:ch211-1e14.1
si:ch211-1e14.1
chr20_+_37866686 0.54 ENSDART00000036546
vash2
vasohibin 2
chr19_+_37135700 0.54 ENSDART00000103159
smim12
small integral membrane protein 12
chr7_+_18176162 0.53 ENSDART00000109171
rce1a
Ras converting CAAX endopeptidase 1a
chr1_-_45889820 0.52 ENSDART00000144735
pnpla6
patatin-like phospholipase domain containing 6
chr20_+_22067337 0.51 ENSDART00000152636
clocka
clock circadian regulator a
chr20_-_6184167 0.51 ENSDART00000147451
b4galt6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr9_+_27750490 0.49 ENSDART00000125303
ENSDART00000189279
ENSDART00000021065
ENSDART00000148060
rab5b
RAB5B, member RAS oncogene family
chr23_+_45785563 0.48 ENSDART00000186027
CABZ01088036.1

chr18_-_39188664 0.48 ENSDART00000162983
mapk6
mitogen-activated protein kinase 6
chr21_+_34686764 0.46 ENSDART00000005479
chm
choroideremia (Rab escort protein 1)
chr1_+_1941031 0.45 ENSDART00000110331
PTGFRN
si:ch211-132g1.7
chr23_+_27779452 0.44 ENSDART00000134785
kmt2d
lysine (K)-specific methyltransferase 2D
chr1_+_37752171 0.44 ENSDART00000183247
ENSDART00000189756
ENSDART00000139448
GALNTL6
si:ch211-15e22.3
chr23_-_33944597 0.43 ENSDART00000133223
si:dkey-190g6.2
si:dkey-190g6.2
chr23_+_16469530 0.43 ENSDART00000132898
ntsr1
neurotensin receptor 1 (high affinity)
chr8_+_7801060 0.43 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr9_+_11034314 0.43 ENSDART00000032695
asic4a
acid-sensing (proton-gated) ion channel family member 4a
chr2_+_25198648 0.39 ENSDART00000110922
ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr14_-_4043818 0.39 ENSDART00000179870
snx25
sorting nexin 25
chr9_-_27749936 0.38 ENSDART00000064156
tbccd1
TBCC domain containing 1
chr9_-_34882516 0.38 ENSDART00000011163
asmtl
acetylserotonin O-methyltransferase-like
chr3_+_52953489 0.38 ENSDART00000125136
dsn1
DSN1 homolog, MIS12 kinetochore complex component
chr11_+_41560792 0.38 ENSDART00000127292
kcnab2a
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr2_-_43739559 0.37 ENSDART00000138947
kif5ba
kinesin family member 5B, a
chr3_+_15773991 0.37 ENSDART00000089923
znf652
zinc finger protein 652
chr10_-_39283883 0.36 ENSDART00000023831
cry5
cryptochrome circadian clock 5
chr12_+_23991276 0.36 ENSDART00000153136
psme4b
proteasome activator subunit 4b
chr5_-_43071058 0.36 ENSDART00000165546
si:dkey-245n4.2
si:dkey-245n4.2
chr8_-_16406440 0.36 ENSDART00000034004
faf1
Fas (TNFRSF6) associated factor 1
chr3_+_18579806 0.35 ENSDART00000180967
ENSDART00000089765
arhgap17b
Rho GTPase activating protein 17b
chr24_-_25166416 0.35 ENSDART00000111552
ENSDART00000169495
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr2_-_30784198 0.35 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr16_-_17347727 0.34 ENSDART00000144392
zyx
zyxin
chr7_+_53498152 0.32 ENSDART00000184497
znf609b
zinc finger protein 609b
chr21_+_39432248 0.32 ENSDART00000179938
pafah1b1b
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b
chr2_-_20666920 0.31 ENSDART00000143437
ENSDART00000114546
ENSDART00000136113
ENSDART00000179247
dusp12
dual specificity phosphatase 12
chr12_-_31484677 0.30 ENSDART00000066578
tectb
tectorin beta
chr22_+_2751887 0.30 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr5_+_66044128 0.29 ENSDART00000165573
jak2b
Janus kinase 2b
chr15_-_15910226 0.27 ENSDART00000154219
synrg
synergin, gamma
chr2_+_38804223 0.27 ENSDART00000147939
carmil3
capping protein regulator and myosin 1 linker 3
chr20_-_20248408 0.27 ENSDART00000183234
ppp2r5ea
protein phosphatase 2, regulatory subunit B', epsilon isoform a
chr20_+_51813432 0.26 ENSDART00000127444
taf1a
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A
chr23_-_1056808 0.26 ENSDART00000081961
zgc:113423
zgc:113423
chr17_-_1407593 0.25 ENSDART00000157622
ENSDART00000159458
zbtb42
zinc finger and BTB domain containing 42
chr11_+_1602916 0.25 ENSDART00000184434
ENSDART00000112597
ENSDART00000192165
si:dkey-40c23.2
si:dkey-40c23.3
si:dkey-40c23.2
si:dkey-40c23.3
chr20_-_5052786 0.25 ENSDART00000138818
ENSDART00000181655
ENSDART00000164274
arid1b
AT rich interactive domain 1B (SWI1-like)
chr17_-_13072334 0.25 ENSDART00000159598
CU469462.1

chr1_-_58562129 0.24 ENSDART00000159070
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr7_-_73852594 0.23 ENSDART00000183194
zgc:165555
zgc:165555
chr7_+_73827805 0.23 ENSDART00000109316
zgc:173587
zgc:173587
chr6_+_40591149 0.23 ENSDART00000189060
ENSDART00000188298
frs3
fibroblast growth factor receptor substrate 3
chr12_+_31422557 0.23 ENSDART00000153179
zdhhc6
zinc finger, DHHC-type containing 6
chr17_+_5768608 0.22 ENSDART00000157039
rp1l1a
retinitis pigmentosa 1-like 1a
chr8_+_35964482 0.22 ENSDART00000129357
ENSDART00000154953
glt1d1
glycosyltransferase 1 domain containing 1
chr5_+_12908781 0.22 ENSDART00000051663
ppil2
peptidylprolyl isomerase (cyclophilin)-like 2
chr7_+_13988075 0.22 ENSDART00000186812
furina
furin (paired basic amino acid cleaving enzyme) a
chr11_+_24851671 0.21 ENSDART00000167659
ipo9
importin 9
chr6_+_41446541 0.20 ENSDART00000029553
ENSDART00000128756
ENSDART00000144864
rsg1
REM2 and RAB-like small GTPase 1
chr12_-_20658285 0.19 ENSDART00000080888
snf8
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr4_+_288633 0.19 ENSDART00000183304
FO834823.1

chr16_-_13818061 0.16 ENSDART00000132982
ENSDART00000144856
leng9
leukocyte receptor cluster (LRC) member 9
chr10_+_39283985 0.16 ENSDART00000016464
dcps
decapping enzyme, scavenger
chr20_+_26943072 0.16 ENSDART00000153215
cdca4
cell division cycle associated 4
chr3_-_56896702 0.16 ENSDART00000023265
ush1ga
Usher syndrome 1Ga (autosomal recessive)
chr13_+_4883377 0.16 ENSDART00000181530
ENSDART00000092521
micu1
mitochondrial calcium uptake 1
chr11_+_40649412 0.15 ENSDART00000043016
ENSDART00000134560
slc45a1
solute carrier family 45, member 1
chr2_+_30465102 0.13 ENSDART00000188404
neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr2_+_56213694 0.13 ENSDART00000162582
upf1
upf1 regulator of nonsense transcripts homolog (yeast)
chr19_-_6983002 0.13 ENSDART00000104891
znf384l
zinc finger protein 384 like
chr2_+_29491314 0.12 ENSDART00000181774
dlgap1a
discs, large (Drosophila) homolog-associated protein 1a
chr16_+_35905031 0.11 ENSDART00000162411
sh3d21
SH3 domain containing 21
chr14_-_31856819 0.11 ENSDART00000003345
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr19_-_15434813 0.11 ENSDART00000019843
ftr55
finTRIM family, member 55
chr24_-_23839647 0.10 ENSDART00000125190
rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr4_-_14315855 0.10 ENSDART00000133325
nell2b
neural EGFL like 2b
chr7_+_39360797 0.10 ENSDART00000173481
acp2
acid phosphatase 2, lysosomal
chr7_+_20656942 0.09 ENSDART00000100898
tnfsf12
TNF superfamily member 12
chr21_+_40254429 0.08 ENSDART00000133894
or115-8
odorant receptor, family F, subfamily 115, member 8
chr6_-_21678263 0.08 ENSDART00000038777
si:dkey-43k4.5
si:dkey-43k4.5
chr6_-_35310224 0.08 ENSDART00000148997
nos1apa
nitric oxide synthase 1 (neuronal) adaptor protein a
chr4_-_77332032 0.07 ENSDART00000168628
ENSDART00000172025
slco1f3
solute carrier organic anion transporter family, member 1F3
chr3_+_12718100 0.07 ENSDART00000162343
ENSDART00000192425
cyp2k20
cytochrome P450, family 2, subfamily k, polypeptide 20
chr18_+_7264961 0.07 ENSDART00000188461
CABZ01015105.1

chr16_-_24561354 0.06 ENSDART00000193278
ENSDART00000126274
si:ch211-79k12.2
si:ch211-79k12.2
chr12_-_18872927 0.06 ENSDART00000187717
shisa8b
shisa family member 8b
chr22_+_26853254 0.06 ENSDART00000182487
tmem186
transmembrane protein 186
chr1_-_58561963 0.05 ENSDART00000165040
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr9_-_40873934 0.04 ENSDART00000066424
pofut2
protein O-fucosyltransferase 2
chr4_-_22519516 0.03 ENSDART00000130409
ENSDART00000186258
ENSDART00000002851
ENSDART00000123801
kdm7aa
lysine (K)-specific demethylase 7Aa
chr12_-_16524727 0.03 ENSDART00000166645
FO704724.1

chr22_+_21317597 0.02 ENSDART00000132605
shc2
SHC (Src homology 2 domain containing) transforming protein 2
chr14_-_2209742 0.02 ENSDART00000054889
pcdh2ab5
protocadherin 2 alpha b 5
chr3_+_1096831 0.02 ENSDART00000132817
si:ch1073-322p19.1
si:ch1073-322p19.1
chr19_+_16064439 0.01 ENSDART00000151169
gmeb1
glucocorticoid modulatory element binding protein 1
chr8_-_3346692 0.01 ENSDART00000057874
FUT9 (1 of many)
zgc:103510
chr21_+_21679086 0.00 ENSDART00000146225
or125-5
odorant receptor, family E, subfamily 125, member 5
chr18_-_26894732 0.00 ENSDART00000147735
ENSDART00000188938
BX470164.1
si:dkey-24l11.2

si:dkey-24l11.2
chr18_+_19419120 0.00 ENSDART00000025107
map2k1
mitogen-activated protein kinase kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of six4a+six4b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1903373 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.2 1.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 0.5 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 1.7 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.4 GO:0051661 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.6 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.4 GO:0035092 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.3 GO:0031650 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.4 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 1.1 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.5 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.4 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.8 GO:0090279 regulation of calcium ion import(GO:0090279)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0098900 regulation of action potential(GO:0098900)
0.0 0.6 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.4 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.8 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.9 GO:0009648 photoperiodism(GO:0009648)
0.0 1.0 GO:0032007 insulin receptor signaling pathway(GO:0008286) negative regulation of TOR signaling(GO:0032007)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.4 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.5 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 1.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.1 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016) regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.1 0.4 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.5 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.3 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.2 GO:0035060 brahma complex(GO:0035060)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 0.4 GO:0003913 DNA photolyase activity(GO:0003913)
0.1 0.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.5 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.8 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 4.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.1 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination