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PRJNA195909:zebrafish embryo and larva development

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Results for smarcc1a+smarcc1b

Z-value: 1.25

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Transcription factors associated with smarcc1a+smarcc1b

Gene Symbol Gene ID Gene Info
smarcc1a
ENSDARG00000017397 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a
smarcc1b
ENSDARG00000098919 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
smarcc1bdr11_v1_chr19_-_19379084_19379084-0.916.2e-04Click!
smarcc1adr11_v1_chr16_-_42461263_42461263-0.684.4e-02Click!

Activity profile of smarcc1a+smarcc1b motif

Sorted Z-values of smarcc1a+smarcc1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_59252973 7.79 ENSDART00000167061
si:ch1073-286c18.5
si:ch1073-286c18.5
chr11_-_24681292 2.49 ENSDART00000089601
olfml3b
olfactomedin-like 3b
chr22_-_15593824 2.45 ENSDART00000123125
tpm4a
tropomyosin 4a
chr5_-_67471375 2.12 ENSDART00000147009
si:dkey-251i10.2
si:dkey-251i10.2
chr13_+_4671698 2.08 ENSDART00000164617
ENSDART00000128494
ENSDART00000165776
pla2g12b
phospholipase A2, group XIIB
chr12_-_30841679 2.07 ENSDART00000105594
crygmx
crystallin, gamma MX
chr3_-_61185746 2.01 ENSDART00000028219
pvalb4
parvalbumin 4
chr16_+_23403602 2.01 ENSDART00000159848
s100w
S100 calcium binding protein W
chr3_-_32818607 1.79 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr22_+_37888249 1.78 ENSDART00000076082
fetub
fetuin B
chr9_-_22076368 1.67 ENSDART00000128486
crygm2a
crystallin, gamma M2a
chr6_-_13783604 1.66 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
cryba2a
crystallin, beta A2a
chr22_-_26595027 1.66 ENSDART00000184162
CABZ01072309.1

chr1_-_25679339 1.59 ENSDART00000161703
ENSDART00000054230
fgg
fibrinogen gamma chain
chr22_+_22888 1.50 ENSDART00000082471
mfap2
microfibril associated protein 2
chr7_-_35432901 1.49 ENSDART00000026712
mmp2
matrix metallopeptidase 2
chr16_-_16182319 1.49 ENSDART00000103815
stmn2a
stathmin 2a
chr3_+_24197934 1.47 ENSDART00000055609
atf4b
activating transcription factor 4b
chr2_+_48288461 1.45 ENSDART00000141495
hes6
hes family bHLH transcription factor 6
chr11_-_28614608 1.45 ENSDART00000065853
dhrs3b
dehydrogenase/reductase (SDR family) member 3b
chr16_-_14397003 1.44 ENSDART00000170957
crabp2a
cellular retinoic acid binding protein 2, a
chr20_-_26531850 1.43 ENSDART00000183317
ENSDART00000131994
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr4_+_5249494 1.41 ENSDART00000150391
si:ch211-214j24.14
si:ch211-214j24.14
chr11_-_3334248 1.41 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr7_+_22657566 1.38 ENSDART00000141048
ponzr5
plac8 onzin related protein 5
chr22_+_11756040 1.36 ENSDART00000105808
krt97
keratin 97
chr20_-_32446406 1.35 ENSDART00000026635
nr2e1
nuclear receptor subfamily 2, group E, member 1
chr20_-_26532167 1.33 ENSDART00000061914
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr16_+_33655890 1.33 ENSDART00000143757
fhl3a
four and a half LIM domains 3a
chr19_-_5332784 1.32 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr21_+_25765734 1.30 ENSDART00000021664
cldnb
claudin b
chr6_+_29791164 1.29 ENSDART00000017424
ptmaa
prothymosin, alpha a
chr23_-_35694461 1.29 ENSDART00000185884
tuba1c
tubulin, alpha 1c
chr14_+_34486629 1.26 ENSDART00000131861
tmsb2
thymosin beta 2
chr2_-_2020044 1.26 ENSDART00000024135
tubb2
tubulin, beta 2A class IIa
chr6_-_18976168 1.25 ENSDART00000170039
sept9b
septin 9b
chr12_-_6159545 1.25 ENSDART00000152487
rltgr
RAMP-like triterpene glycoside receptor
chr5_-_25582721 1.24 ENSDART00000123986
anxa1a
annexin A1a
chr7_+_25033924 1.24 ENSDART00000170873
sb:cb1058
sb:cb1058
chr4_-_5291256 1.23 ENSDART00000150864
SNAP91 (1 of many)
si:ch211-214j24.9
chr13_+_24280380 1.22 ENSDART00000184115
acta1b
actin, alpha 1b, skeletal muscle
chr11_+_26609110 1.22 ENSDART00000042322
map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr13_+_2908764 1.21 ENSDART00000162362
wu:fj16a03
wu:fj16a03
chr13_+_43247936 1.21 ENSDART00000126850
ENSDART00000165331
smoc2
SPARC related modular calcium binding 2
chr5_-_20195350 1.21 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr16_+_42829735 1.21 ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr6_+_56141852 1.20 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr8_+_25900049 1.20 ENSDART00000124300
ENSDART00000127618
ENSDART00000024009
rhoab
ras homolog gene family, member Ab
chr25_-_22187397 1.20 ENSDART00000123211
ENSDART00000139110
pkp3a
plakophilin 3a
chr14_-_38878356 1.19 ENSDART00000173082
ENSDART00000039788
uqcrq
ubiquinol-cytochrome c reductase, complex III subunit VII
chr17_-_5583345 1.19 ENSDART00000035944
clic5a
chloride intracellular channel 5a
chr25_-_173165 1.19 ENSDART00000193594
CABZ01114053.1

chr18_-_12052132 1.18 ENSDART00000074361
zgc:110789
zgc:110789
chr3_+_27027781 1.18 ENSDART00000065495
emp2
epithelial membrane protein 2
chr23_-_21471022 1.17 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr3_-_4303262 1.16 ENSDART00000112819
si:dkey-73p2.2
si:dkey-73p2.2
chr20_+_34770197 1.15 ENSDART00000018304
mcm3
minichromosome maintenance complex component 3
chr3_+_23752150 1.14 ENSDART00000146636
hoxb2a
homeobox B2a
chr19_-_7420867 1.14 ENSDART00000081741
rab25a
RAB25, member RAS oncogene family a
chr6_+_56147812 1.14 ENSDART00000150219
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr5_-_30615901 1.14 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr3_-_34801041 1.13 ENSDART00000103043
nsfa
N-ethylmaleimide-sensitive factor a
chr7_-_28696556 1.12 ENSDART00000148822
adgrg1
adhesion G protein-coupled receptor G1
chr17_+_7595356 1.12 ENSDART00000130625
si:dkeyp-110a12.4
si:dkeyp-110a12.4
chr12_+_25945560 1.10 ENSDART00000109799
mmrn2b
multimerin 2b
chr1_+_12766351 1.09 ENSDART00000165785
pcdh10a
protocadherin 10a
chr1_-_22861348 1.09 ENSDART00000139412
SMIM18
si:dkey-92j12.6
chr18_+_45114392 1.08 ENSDART00000172328
large2
LARGE xylosyl- and glucuronyltransferase 2
chr1_-_10071422 1.08 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr19_+_31771270 1.07 ENSDART00000147474
stmn2b
stathmin 2b
chr14_+_33722950 1.07 ENSDART00000075312
apln
apelin
chr2_+_47581997 1.07 ENSDART00000112579
scg2b
secretogranin II (chromogranin C), b
chr20_+_34915945 1.07 ENSDART00000153064
snap25a
synaptosomal-associated protein, 25a
chr13_+_22479988 1.06 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr5_-_8164439 1.05 ENSDART00000189912
slc1a3a
solute carrier family 1 (glial high affinity glutamate transporter), member 3a
chr9_-_48370645 1.04 ENSDART00000140185
col28a2a
collagen, type XXVIII, alpha 2a
chr18_-_3166726 1.04 ENSDART00000165002
aqp11
aquaporin 11
chr22_+_11775269 1.03 ENSDART00000140272
krt96
keratin 96
chr25_+_21324588 1.01 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr23_-_12345764 1.00 ENSDART00000133956
phactr3a
phosphatase and actin regulator 3a
chr16_+_20915319 1.00 ENSDART00000079383
hoxa9b
homeobox A9b
chr20_+_26880668 1.00 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr19_-_103289 1.00 ENSDART00000143118
adgrb1b
adhesion G protein-coupled receptor B1b
chr22_+_11857356 1.00 ENSDART00000179540
mras
muscle RAS oncogene homolog
chr13_-_16222388 0.99 ENSDART00000182861
zgc:110045
zgc:110045
chr16_-_21785261 0.99 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr12_-_26064480 0.98 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
ldb3b
LIM domain binding 3b
chr25_-_18140537 0.98 ENSDART00000113581
kitlga
kit ligand a
chr3_-_53533128 0.97 ENSDART00000183591
notch3
notch 3
chr3_-_26017592 0.97 ENSDART00000030890
hmox1a
heme oxygenase 1a
chr14_-_43000836 0.96 ENSDART00000162714
pcdh10b
protocadherin 10b
chr3_-_26017831 0.96 ENSDART00000179982
hmox1a
heme oxygenase 1a
chr19_-_6385594 0.95 ENSDART00000104950
atp1a3a
ATPase Na+/K+ transporting subunit alpha 3a
chr2_+_35612621 0.95 ENSDART00000143082
si:dkey-4i23.5
si:dkey-4i23.5
chr10_+_37145007 0.94 ENSDART00000131777
cuedc1a
CUE domain containing 1a
chr21_-_44104600 0.94 ENSDART00000044599
oatx
organic anion transporter X
chr3_+_37574885 0.94 ENSDART00000055225
wnt9b
wingless-type MMTV integration site family, member 9B
chr7_+_34492744 0.93 ENSDART00000109635
ENSDART00000173844
calml4a
calmodulin-like 4a
chr13_+_23988442 0.93 ENSDART00000010918
agt
angiotensinogen
chr22_-_38621438 0.92 ENSDART00000098330
nppc
natriuretic peptide C
chr15_-_2657508 0.92 ENSDART00000102086
cldna
claudin a
chr1_+_41849152 0.92 ENSDART00000053685
smox
spermine oxidase
chr25_-_22191733 0.91 ENSDART00000067478
pkp3a
plakophilin 3a
chr7_+_73630751 0.91 ENSDART00000159745
PCP4L1
si:dkey-46i9.1
chr3_+_20156956 0.91 ENSDART00000125281
ngfra
nerve growth factor receptor a (TNFR superfamily, member 16)
chr25_-_18140305 0.90 ENSDART00000180222
kitlga
kit ligand a
chr12_-_4388704 0.90 ENSDART00000152168
si:ch211-173d10.1
si:ch211-173d10.1
chr20_+_6663544 0.90 ENSDART00000135390
tns3.2
tensin 3, tandem duplicate 2
chr5_-_55623443 0.90 ENSDART00000005671
ENSDART00000176341
hnrpkl
heterogeneous nuclear ribonucleoprotein K, like
chr16_+_23960744 0.89 ENSDART00000058965
apoeb
apolipoprotein Eb
chr2_+_30379650 0.89 ENSDART00000129542
crispld1b
cysteine-rich secretory protein LCCL domain containing 1b
chr11_+_8660158 0.89 ENSDART00000169141
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a
chr7_+_7048245 0.89 ENSDART00000001649
actn3b
actinin alpha 3b
chr11_-_10770053 0.89 ENSDART00000179213
slc4a10a
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr12_-_37299646 0.88 ENSDART00000146142
ENSDART00000085201
pmp22b
peripheral myelin protein 22b
chr13_-_21701323 0.88 ENSDART00000164112
si:dkey-191g9.7
si:dkey-191g9.7
chr2_+_47582681 0.88 ENSDART00000187579
scg2b
secretogranin II (chromogranin C), b
chr21_+_20383837 0.87 ENSDART00000026430
hspb11
heat shock protein, alpha-crystallin-related, b11
chr8_+_39634114 0.86 ENSDART00000144293
msi1
musashi RNA-binding protein 1
chr20_-_39103119 0.86 ENSDART00000143379
rcan2
regulator of calcineurin 2
chr21_-_30545121 0.86 ENSDART00000019199
rab39ba
RAB39B, member RAS oncogene family a
chr13_+_829585 0.85 ENSDART00000029051
gsta.2
glutathione S-transferase, alpha tandem duplicate 2
chr4_-_16412084 0.85 ENSDART00000188460
dcn
decorin
chr14_+_33882973 0.85 ENSDART00000019396
clic2
chloride intracellular channel 2
chr2_+_55984788 0.84 ENSDART00000183599
nmrk2
nicotinamide riboside kinase 2
chr10_+_38610741 0.84 ENSDART00000126444
mmp13a
matrix metallopeptidase 13a
chr23_-_7797207 0.83 ENSDART00000181611
myt1b
myelin transcription factor 1b
chr7_-_35126374 0.83 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr1_-_5746030 0.83 ENSDART00000150863
nrp2a
neuropilin 2a
chr7_-_35314347 0.82 ENSDART00000005053
slc12a4
solute carrier family 12 (potassium/chloride transporter), member 4
chr14_+_6423973 0.82 ENSDART00000051556
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr15_-_19771981 0.82 ENSDART00000175502
ENSDART00000159475
picalmb
phosphatidylinositol binding clathrin assembly protein b
chr10_+_4987766 0.81 ENSDART00000121959
si:ch73-234b20.5
si:ch73-234b20.5
chr14_-_17588345 0.81 ENSDART00000143486
selenot2
selenoprotein T, 2
chr19_+_5072918 0.81 ENSDART00000037126
eno2
enolase 2
chr12_-_1951233 0.80 ENSDART00000005676
ENSDART00000127937
sox9a
SRY (sex determining region Y)-box 9a
chr19_-_10881486 0.80 ENSDART00000168852
ENSDART00000160438
PSMD4 (1 of many)
psmd4a
proteasome 26S subunit, non-ATPase 4
proteasome 26S subunit, non-ATPase 4a
chr23_+_24124684 0.79 ENSDART00000144478
si:dkey-21o19.2
si:dkey-21o19.2
chr15_-_28107502 0.79 ENSDART00000152270
ENSDART00000167129
cryba1a
crystallin, beta A1a
chr23_-_7799184 0.79 ENSDART00000190946
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr11_-_18253111 0.78 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr10_+_22771176 0.78 ENSDART00000192046
tmem88a
transmembrane protein 88 a
chr9_-_2594410 0.78 ENSDART00000188306
ENSDART00000164276
sp9
sp9 transcription factor
chr20_-_23439011 0.78 ENSDART00000022887
slc10a4
solute carrier family 10, member 4
chr7_-_8504355 0.78 ENSDART00000173067
loc564660
hypothetical protein LOC564660
chr22_-_13350240 0.77 ENSDART00000154095
ENSDART00000155118
si:ch211-227m13.1
si:ch211-227m13.1
chr11_+_13630107 0.77 ENSDART00000172220
si:ch211-1a19.3
si:ch211-1a19.3
chr6_-_15757867 0.76 ENSDART00000063665
ackr3b
atypical chemokine receptor 3b
chr8_+_39511932 0.76 ENSDART00000113511
lzts1
leucine zipper, putative tumor suppressor 1
chr12_+_20336070 0.75 ENSDART00000066385
zgc:163057
zgc:163057
chr1_-_411331 0.75 ENSDART00000092524
rasa3
RAS p21 protein activator 3
chr14_-_11456724 0.75 ENSDART00000110424
si:ch211-153b23.4
si:ch211-153b23.4
chr4_-_6809323 0.74 ENSDART00000099467
ifrd1
interferon-related developmental regulator 1
chr13_+_25433774 0.74 ENSDART00000141255
si:dkey-51a16.9
si:dkey-51a16.9
chr25_-_18330503 0.73 ENSDART00000104496
dusp6
dual specificity phosphatase 6
chr19_-_33212023 0.73 ENSDART00000189209
trib1
tribbles pseudokinase 1
chr2_+_38264964 0.73 ENSDART00000182068
dhrs1
dehydrogenase/reductase (SDR family) member 1
chr5_-_66028714 0.72 ENSDART00000022625
ENSDART00000164228
nrarpb
NOTCH regulated ankyrin repeat protein b
chr4_+_1600034 0.72 ENSDART00000146779
slc38a2
solute carrier family 38, member 2
chr22_-_11724563 0.72 ENSDART00000190796
ENSDART00000184744
krt222
keratin 222
chr22_-_4644484 0.71 ENSDART00000167748
fbn2b
fibrillin 2b
chr16_+_9762261 0.71 ENSDART00000020654
psmd4b
proteasome 26S subunit, non-ATPase 4b
chr7_-_26436436 0.71 ENSDART00000019035
ENSDART00000123395
her8a
hairy-related 8a
chr15_-_19772372 0.71 ENSDART00000152729
picalmb
phosphatidylinositol binding clathrin assembly protein b
chr6_+_3710865 0.71 ENSDART00000170781
phospho2
phosphatase, orphan 2
chr3_-_32320537 0.71 ENSDART00000113550
ENSDART00000168483
si:dkey-16p21.7
si:dkey-16p21.7
chr20_-_40319890 0.71 ENSDART00000075112
clvs2
clavesin 2
chr14_+_30279391 0.70 ENSDART00000172794
fgl1
fibrinogen-like 1
chr5_+_15819651 0.69 ENSDART00000081230
ENSDART00000186969
ENSDART00000134206
hspb8
heat shock protein b8
chr17_+_58211 0.69 ENSDART00000157642
si:ch1073-209e23.1
si:ch1073-209e23.1
chr14_+_49382180 0.69 ENSDART00000158329
tnip1
TNFAIP3 interacting protein 1
chr25_+_13191391 0.69 ENSDART00000109937
si:ch211-147m6.2
si:ch211-147m6.2
chr16_-_48673938 0.69 ENSDART00000156969
notchl
notch homolog, like
chr7_+_20512419 0.68 ENSDART00000173907
si:dkey-19b23.14
si:dkey-19b23.14
chr5_-_48260145 0.68 ENSDART00000044083
ENSDART00000163250
ENSDART00000135911
mef2cb
myocyte enhancer factor 2cb
chr3_-_39695856 0.68 ENSDART00000148247
b9d1
B9 protein domain 1
chr14_-_34044369 0.67 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cyfip2
cytoplasmic FMR1 interacting protein 2
chr9_-_710896 0.67 ENSDART00000180478
ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr4_+_16715267 0.67 ENSDART00000143849
pkp2
plakophilin 2
chr7_+_23875269 0.67 ENSDART00000101406
rab39bb
RAB39B, member RAS oncogene family b
chr14_-_13048355 0.67 ENSDART00000166434
si:dkey-35h6.1
si:dkey-35h6.1
chr3_+_7617353 0.67 ENSDART00000165551
zgc:109949
zgc:109949
chr7_-_13381129 0.67 ENSDART00000164326
si:ch73-119p20.1
si:ch73-119p20.1
chr19_+_43314700 0.67 ENSDART00000049045
ENSDART00000133158
matn1
matrilin 1
chr4_+_77735212 0.67 ENSDART00000160716
si:dkey-238k10.1
si:dkey-238k10.1
chr14_-_42997145 0.67 ENSDART00000172801
pcdh10b
protocadherin 10b
chr4_-_73787702 0.66 ENSDART00000136328
ENSDART00000150546
si:dkey-262g12.3
si:dkey-262g12.3
chr11_+_24251141 0.66 ENSDART00000182684
pnp4a
purine nucleoside phosphorylase 4a
chr13_+_22480496 0.66 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr22_+_10646928 0.65 ENSDART00000038465
rassf1
Ras association (RalGDS/AF-6) domain family 1
chr24_+_13869092 0.64 ENSDART00000176492
eya1
EYA transcriptional coactivator and phosphatase 1
chr2_-_985417 0.64 ENSDART00000140540
si:ch211-241e1.3
si:ch211-241e1.3
chr1_-_52498146 0.64 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr3_-_58650057 0.64 ENSDART00000057640
dhrs7ca
dehydrogenase/reductase (SDR family) member 7Ca
chr25_+_13191615 0.63 ENSDART00000168849
si:ch211-147m6.2
si:ch211-147m6.2
chr5_+_4338874 0.63 ENSDART00000141866
sat1a.1
spermidine/spermine N1-acetyltransferase 1a, duplicate 1
chr10_-_6454386 0.63 ENSDART00000168549
ca9
carbonic anhydrase IX
chr22_-_12746539 0.63 ENSDART00000175374
plcd4a
phospholipase C, delta 4a
chr10_+_4499943 0.63 ENSDART00000125299
plk2a
polo-like kinase 2a (Drosophila)
chr16_+_14033121 0.62 ENSDART00000135844
rusc1
RUN and SH3 domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of smarcc1a+smarcc1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.4 1.7 GO:0048914 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.4 1.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.4 1.2 GO:0003071 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.3 1.0 GO:0098725 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
0.3 1.2 GO:0046436 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.3 0.9 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.3 0.8 GO:0061317 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.2 1.0 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.2 0.7 GO:0003249 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.2 3.3 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 1.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 0.6 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.2 1.6 GO:0021794 thalamus development(GO:0021794)
0.2 3.0 GO:0043248 proteasome assembly(GO:0043248)
0.2 3.0 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.2 0.6 GO:0035902 response to immobilization stress(GO:0035902)
0.2 2.5 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.2 2.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 0.8 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
0.2 1.1 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2 2.8 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 1.1 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.2 1.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 0.5 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.2 0.6 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.2 0.9 GO:0071800 podosome assembly(GO:0071800)
0.2 0.8 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.2 0.5 GO:0032263 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.1 0.4 GO:0002676 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 0.4 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 1.4 GO:0033700 phospholipid efflux(GO:0033700)
0.1 0.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.8 GO:0070254 mucus secretion(GO:0070254)
0.1 1.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.6 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.5 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.4 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.6 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 1.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.8 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 1.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.6 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.7 GO:0060420 regulation of heart growth(GO:0060420)
0.1 1.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.3 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.8 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 1.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.4 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.7 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.4 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 0.6 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 2.5 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 2.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.7 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.1 0.4 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.5 GO:0019344 homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.1 0.6 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.3 GO:0035889 otolith tethering(GO:0035889)
0.1 0.6 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.4 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 2.4 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.7 GO:0006868 glutamine transport(GO:0006868)
0.1 0.6 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.2 GO:0016038 absorption of visible light(GO:0016038)
0.1 0.8 GO:0001964 startle response(GO:0001964)
0.1 1.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.4 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.2 GO:0097324 melanocyte migration(GO:0097324)
0.1 1.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.3 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 1.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.6 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.5 GO:0044259 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.1 0.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 1.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 2.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 2.2 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.5 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.8 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 1.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.0 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.9 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.1 0.9 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.2 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.8 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 1.1 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.4 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.9 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.9 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.6 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 2.0 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 3.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.4 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 1.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.3 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 4.9 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.4 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.3 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.4 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.8 GO:0015671 oxygen transport(GO:0015671)
0.0 0.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 1.3 GO:0060840 artery development(GO:0060840)
0.0 1.9 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 1.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.6 GO:0009749 response to glucose(GO:0009749)
0.0 0.4 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.5 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.7 GO:0042476 odontogenesis(GO:0042476)
0.0 0.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0009791 post-embryonic development(GO:0009791)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.8 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.4 GO:1902882 regulation of response to oxidative stress(GO:1902882)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.3 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.7 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0019405 alditol catabolic process(GO:0019405)
0.0 0.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 1.5 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 1.5 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.0 GO:0045010 actin nucleation(GO:0045010)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.7 GO:0034111 negative regulation of homotypic cell-cell adhesion(GO:0034111) negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.6 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.3 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.9 GO:0000910 cytokinesis(GO:0000910)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.0 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 1.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.8 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.9 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.5 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.3 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.6 GO:0007626 locomotory behavior(GO:0007626)
0.0 0.3 GO:0060078 regulation of postsynaptic membrane potential(GO:0060078)
0.0 0.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.6 GO:0016358 dendrite development(GO:0016358)
0.0 0.5 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.7 GO:0034620 cellular response to unfolded protein(GO:0034620)
0.0 0.1 GO:0060232 regulation of epithelial to mesenchymal transition(GO:0010717) delamination(GO:0060232)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.7 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.4 GO:0060914 heart formation(GO:0060914)
0.0 0.1 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 1.3 GO:1990266 neutrophil migration(GO:1990266)
0.0 0.1 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.8 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 0.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 2.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 1.5 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.5 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.9 GO:0030057 desmosome(GO:0030057)
0.1 0.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 1.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.7 GO:0030175 filopodium(GO:0030175)
0.1 0.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 1.2 GO:0005869 dynactin complex(GO:0005869)
0.1 0.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 7.8 GO:0005882 intermediate filament(GO:0005882)
0.1 0.3 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 1.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 3.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.8 GO:0005902 microvillus(GO:0005902)
0.1 1.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.5 GO:0042583 chromaffin granule(GO:0042583)
0.0 3.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.6 GO:0030426 growth cone(GO:0030426)
0.0 1.7 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.8 GO:0043195 terminal bouton(GO:0043195)
0.0 2.6 GO:0030141 secretory granule(GO:0030141)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 3.4 GO:0044420 extracellular matrix component(GO:0044420)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 3.0 GO:0005884 actin filament(GO:0005884)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 1.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0030428 cell septum(GO:0030428)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 5.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0016234 inclusion body(GO:0016234)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0032426 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.3 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 2.8 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.4 1.1 GO:0031704 apelin receptor binding(GO:0031704)
0.3 1.9 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.3 1.2 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.3 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 1.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.7 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 1.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 1.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 1.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.2 0.6 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.2 0.9 GO:0015288 porin activity(GO:0015288)
0.2 0.9 GO:0046592 polyamine oxidase activity(GO:0046592)
0.2 1.4 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 1.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 1.3 GO:0043121 neurotrophin binding(GO:0043121)
0.2 0.5 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 0.6 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.5 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 0.6 GO:0038131 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.1 1.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.4 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 14.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 2.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.6 GO:0019809 spermidine binding(GO:0019809)
0.1 1.1 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 0.8 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.5 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 2.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.4 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.3 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 5.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.0 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.4 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.3 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.2 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.2 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.1 1.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.8 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.7 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.1 2.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.2 GO:0097643 calcitonin receptor activity(GO:0004948) calcitonin family receptor activity(GO:0097642) amylin receptor activity(GO:0097643)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 0.4 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 2.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 2.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 1.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 3.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004100 chitin synthase activity(GO:0004100)
0.0 2.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 8.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.0 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 2.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.0 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.0 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID INSULIN PATHWAY Insulin Pathway
0.0 2.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 0.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 2.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization