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PRJNA195909:zebrafish embryo and larva development

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Results for sp3b

Z-value: 0.94

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Transcription factors associated with sp3b

Gene Symbol Gene ID Gene Info
sp3b
ENSDARG00000007812 Sp3b transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp3bdr11_v1_chr6_-_10725847_107258470.844.5e-03Click!

Activity profile of sp3b motif

Sorted Z-values of sp3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_1211242 1.95 ENSDART00000171287
ENSDART00000165769
poldip3
polymerase (DNA-directed), delta interacting protein 3
chr17_-_2584423 1.57 ENSDART00000013506
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr24_-_36593876 1.44 ENSDART00000160901
CABZ01055365.1

chr12_+_46634736 1.43 ENSDART00000008009
trim16
tripartite motif containing 16
chr7_+_44802353 1.37 ENSDART00000066380
ca7
carbonic anhydrase VII
chr5_+_66132394 1.33 ENSDART00000073892
zgc:114041
zgc:114041
chr16_-_29387215 1.31 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr16_+_25259313 1.29 ENSDART00000058938
fbxo32
F-box protein 32
chr1_-_59232267 1.29 ENSDART00000169658
ENSDART00000163257
akap8l
A kinase (PRKA) anchor protein 8-like
chr17_+_12075805 1.20 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr9_-_8314028 1.17 ENSDART00000102739
si:ch211-145c1.1
si:ch211-145c1.1
chr18_-_127558 1.12 ENSDART00000149556
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr4_-_77551860 1.05 ENSDART00000188176
AL935186.6

chr24_-_20599781 1.04 ENSDART00000179664
ENSDART00000141823
zbtb47b
zinc finger and BTB domain containing 47b
chr25_+_16356083 0.97 ENSDART00000125925
ENSDART00000125444
tead1a
TEA domain family member 1a
chr13_-_17860307 0.97 ENSDART00000135920
ENSDART00000054579
march8
membrane-associated ring finger (C3HC4) 8
chr2_+_58221163 0.94 ENSDART00000157939
FO704813.1

chr6_+_475264 0.90 ENSDART00000193615
LO017974.1

chr20_-_182841 0.90 ENSDART00000064546
si:ch211-241j12.3
si:ch211-241j12.3
chr17_-_53329704 0.89 ENSDART00000193895
exd1
exonuclease 3'-5' domain containing 1
chr4_-_77563411 0.89 ENSDART00000186841
AL935186.8

chr19_+_26340736 0.87 ENSDART00000013497
mylipa
myosin regulatory light chain interacting protein a
chr25_+_22319940 0.82 ENSDART00000154065
ENSDART00000153492
ENSDART00000024866
ENSDART00000154376
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr23_+_35426404 0.82 ENSDART00000164658
si:ch211-225h24.2
si:ch211-225h24.2
chr16_-_7793457 0.79 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr1_+_24469313 0.78 ENSDART00000176581
fam160a1a
family with sequence similarity 160, member A1a
chr18_-_26715655 0.77 ENSDART00000181497
malt3
MALT paracaspase 3
chr1_-_59216197 0.77 ENSDART00000062426
lpar2b
lysophosphatidic acid receptor 2b
chr10_-_641609 0.76 ENSDART00000041236
rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr7_-_45852270 0.74 ENSDART00000170224
shcbp1
SHC SH2-domain binding protein 1
chr2_-_52550135 0.73 ENSDART00000044411
gna11b
guanine nucleotide binding protein (G protein), alpha 11b (Gq class)
chr22_-_20924564 0.73 ENSDART00000100642
ENSDART00000032770
ell
elongation factor RNA polymerase II
chr8_-_410728 0.72 ENSDART00000151255
trim36
tripartite motif containing 36
chr6_+_3334392 0.71 ENSDART00000133707
ENSDART00000130879
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr5_+_68807170 0.71 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr21_-_11646878 0.70 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
cast
calpastatin
chr22_-_20924747 0.69 ENSDART00000185845
ENSDART00000179672
ell
elongation factor RNA polymerase II
chr6_+_41503854 0.69 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr23_+_19655301 0.69 ENSDART00000104441
ENSDART00000135269
abhd6b
abhydrolase domain containing 6b
chr2_+_44512324 0.68 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
pask
PAS domain containing serine/threonine kinase
chr2_+_50062165 0.68 ENSDART00000097939
ENSDART00000138214
zcchc2
zinc finger, CCHC domain containing 2
chr19_+_935565 0.67 ENSDART00000113368
RNF5
ring finger protein 5
chr6_-_21830405 0.66 ENSDART00000151803
ENSDART00000113497
setd5
SET domain containing 5
chr16_-_8120203 0.66 ENSDART00000193430
snrka
SNF related kinase a
chr14_-_24111292 0.65 ENSDART00000186611
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr7_+_74141297 0.65 ENSDART00000164992
rbpms
RNA binding protein with multiple splicing
chr10_-_25543227 0.65 ENSDART00000007778
grik1a
glutamate receptor, ionotropic, kainate 1a
chr3_-_7897563 0.65 ENSDART00000185232
ubn2b
ubinuclein 2b
chr3_-_7897305 0.65 ENSDART00000169757
ubn2b
ubinuclein 2b
chr13_+_45582391 0.63 ENSDART00000058093
ldlrap1b
low density lipoprotein receptor adaptor protein 1b
chr8_-_22739757 0.62 ENSDART00000182167
ENSDART00000171891
iqsec2a
IQ motif and Sec7 domain 2a
chr18_-_41161828 0.62 ENSDART00000114993
CABZ01005876.1

chr5_-_30080332 0.61 ENSDART00000140049
bco2a
beta-carotene oxygenase 2a
chr15_+_40188076 0.61 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr5_-_22969424 0.61 ENSDART00000143869
ENSDART00000172549
si:dkey-237j10.2
si:dkey-237j10.2
chr3_-_58455289 0.61 ENSDART00000052179
cdr2a
cerebellar degeneration-related protein 2a
chr18_-_26715156 0.60 ENSDART00000142043
malt3
MALT paracaspase 3
chr7_+_67325933 0.60 ENSDART00000170575
ENSDART00000183342
nfat5b
nuclear factor of activated T cells 5b
chr8_-_51753604 0.59 ENSDART00000007090
tbx16
T-box 16
chr1_+_15062 0.59 ENSDART00000169005
cep97
centrosomal protein 97
chr14_+_8638353 0.59 ENSDART00000163240
si:dkeyp-115e12.6
si:dkeyp-115e12.6
chr22_-_193234 0.59 ENSDART00000131067
fbxo42
F-box protein 42
chr19_-_6193448 0.59 ENSDART00000151405
erf
Ets2 repressor factor
chr14_-_237130 0.59 ENSDART00000164988
bod1l1
biorientation of chromosomes in cell division 1-like 1
chr23_+_24989387 0.58 ENSDART00000172299
ENSDART00000145307
arhgap4a
Rho GTPase activating protein 4a
chr8_+_8166285 0.58 ENSDART00000147940
plxnb3
plexin B3
chr11_+_42422638 0.57 ENSDART00000042599
ENSDART00000181175
dennd6aa
DENN/MADD domain containing 6Aa
chr22_+_1006573 0.56 ENSDART00000123458
pparda
peroxisome proliferator-activated receptor delta a
chr17_+_37310663 0.56 ENSDART00000157122
elmsan1b
ELM2 and Myb/SANT-like domain containing 1b
chr19_-_2707048 0.56 ENSDART00000166112
il6
interleukin 6 (interferon, beta 2)
chr11_+_42422371 0.56 ENSDART00000163780
dennd6aa
DENN/MADD domain containing 6Aa
chr8_-_410199 0.56 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
trim36
tripartite motif containing 36
chr18_+_3243292 0.56 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr1_+_29741843 0.55 ENSDART00000136066
raph1b
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b
chr20_+_16173618 0.55 ENSDART00000192109
ENSDART00000104112
ENSDART00000129633
zyg11
zyg-11 homolog (C. elegans)
chr5_+_61361815 0.55 ENSDART00000009507
gatsl2
GATS protein-like 2
chr21_-_5056812 0.55 ENSDART00000139713
ENSDART00000140859
zgc:77838
zgc:77838
chr8_-_26709959 0.55 ENSDART00000135215
tmem51a
transmembrane protein 51a
chr19_-_6193067 0.54 ENSDART00000092656
ENSDART00000140347
erf
Ets2 repressor factor
chr15_+_29024895 0.54 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
si:ch211-137a8.2
chr6_-_4214297 0.53 ENSDART00000191433
trak2
trafficking protein, kinesin binding 2
chr3_+_46559639 0.53 ENSDART00000146189
ENSDART00000127832
ENSDART00000151035
raver1
ribonucleoprotein, PTB-binding 1
chr5_-_30074332 0.53 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr13_-_15793585 0.53 ENSDART00000145914
ENSDART00000010286
bag5
BCL2 associated athanogene 5
chr18_-_127873 0.52 ENSDART00000148490
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr7_-_19332293 0.52 ENSDART00000169668
ENSDART00000137575
ENSDART00000090406
dock11
dedicator of cytokinesis 11
chr22_-_34979139 0.52 ENSDART00000116455
ENSDART00000133537
arhgap19
Rho GTPase activating protein 19
chr15_+_11644866 0.52 ENSDART00000188716
slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr8_+_48965767 0.51 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr17_-_8312923 0.51 ENSDART00000064678
lft2
lefty2
chr19_+_1097393 0.51 ENSDART00000168218
CABZ01111953.1

chr2_-_58075414 0.51 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr20_+_46741074 0.51 ENSDART00000145294
si:ch211-57i17.1
si:ch211-57i17.1
chr15_-_17010358 0.50 ENSDART00000156768
hip1
huntingtin interacting protein 1
chr23_+_27703749 0.50 ENSDART00000027224
lmbr1l
limb development membrane protein 1-like
chr20_+_2731436 0.50 ENSDART00000058779
ENSDART00000129870
ENSDART00000132186
ENSDART00000152727
syncrip
synaptotagmin binding, cytoplasmic RNA interacting protein
chr15_-_44601331 0.50 ENSDART00000161514
zgc:165508
zgc:165508
chr15_+_47582207 0.50 ENSDART00000159388
CABZ01087566.1

chr7_-_16598212 0.50 ENSDART00000128488
e2f8
E2F transcription factor 8
chr18_+_6638974 0.50 ENSDART00000162398
c2cd5
C2 calcium-dependent domain containing 5
chr8_+_2656231 0.49 ENSDART00000160833
fam102aa
family with sequence similarity 102, member Aa
chr17_+_14965570 0.48 ENSDART00000066604
gpr137c
G protein-coupled receptor 137c
chr6_+_3334710 0.48 ENSDART00000132848
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr2_-_51087077 0.48 ENSDART00000167987
ftr67
finTRIM family, member 67
chr19_+_13994563 0.48 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr6_-_29377092 0.47 ENSDART00000078665
tmem131
transmembrane protein 131
chr18_+_26086803 0.47 ENSDART00000187911
znf710a
zinc finger protein 710a
chr22_+_835728 0.47 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr12_+_33484458 0.46 ENSDART00000000069
slc9a3r1a
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a
chr1_-_54107321 0.46 ENSDART00000148382
ENSDART00000150357
rfx1b
regulatory factor X, 1b (influences HLA class II expression)
chr6_-_53326421 0.46 ENSDART00000191740
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr24_+_17005647 0.46 ENSDART00000149149
zfx
zinc finger protein, X-linked
chr18_+_6638726 0.46 ENSDART00000142755
ENSDART00000167781
c2cd5
C2 calcium-dependent domain containing 5
chr7_-_64971839 0.45 ENSDART00000164682
sinhcafl
SIN3-HDAC complex associated factor, like
chr8_+_8947623 0.45 ENSDART00000131215
slc35a2
solute carrier family 35 (UDP-galactose transporter), member 2
chr10_+_16168514 0.45 ENSDART00000175513
prrc1
proline-rich coiled-coil 1
chr20_-_33675676 0.44 ENSDART00000147168
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr3_+_29469283 0.44 ENSDART00000103592
fam83fa
family with sequence similarity 83, member Fa
chr5_+_6617401 0.43 ENSDART00000060532
zgc:110796
zgc:110796
chr20_+_4157815 0.43 ENSDART00000113132
gnpat
glyceronephosphate O-acyltransferase
chr1_+_7414318 0.43 ENSDART00000127426
si:ch73-383l1.1
si:ch73-383l1.1
chr25_+_17244532 0.43 ENSDART00000050379
ENSDART00000171322
kdm7ab
lysine (K)-specific demethylase 7Ab
chr20_-_23026223 0.42 ENSDART00000015755
rasl11b
RAS-like, family 11, member B
chr1_+_14454663 0.42 ENSDART00000005067
rbpja
recombination signal binding protein for immunoglobulin kappa J region a
chr17_+_25856671 0.42 ENSDART00000064817
wapla
WAPL cohesin release factor a
chr19_+_4892281 0.42 ENSDART00000150969
cdk12
cyclin-dependent kinase 12
chr15_+_44184367 0.42 ENSDART00000162918
ENSDART00000110060
zgc:165514
zgc:165514
chr2_+_35603637 0.41 ENSDART00000147278
plk3
polo-like kinase 3 (Drosophila)
chr22_-_10752471 0.41 ENSDART00000081191
sass6
SAS-6 centriolar assembly protein
chr25_+_35133404 0.41 ENSDART00000188505
hist1h2a2
histone cluster 1 H2A family member 2
chr8_+_23165749 0.40 ENSDART00000063057
dnajc5aa
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr1_-_54100988 0.40 ENSDART00000192662
rfx1b
regulatory factor X, 1b (influences HLA class II expression)
chr4_-_4612116 0.40 ENSDART00000130601
CABZ01020840.1
Danio rerio apoptosis facilitator Bcl-2-like protein 14 (LOC101885512), mRNA.
chr2_+_36046126 0.40 ENSDART00000085976
ENSDART00000171680
smg7
SMG7 nonsense mediated mRNA decay factor
chr24_-_41180149 0.39 ENSDART00000019975
acvr2ba
activin A receptor type 2Ba
chr16_+_26732086 0.39 ENSDART00000138496
rad54b
RAD54 homolog B (S. cerevisiae)
chr5_+_72152813 0.39 ENSDART00000149910
abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr12_-_28537615 0.38 ENSDART00000067762
MYO1D
si:ch211-94l19.4
chr10_+_22034477 0.38 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
npm1a
nucleophosmin 1a
chr15_+_35933094 0.38 ENSDART00000019976
rhbdd1
rhomboid domain containing 1
chr25_-_29463866 0.38 ENSDART00000155676
ENSDART00000124645
ENSDART00000181055
ENSDART00000192593
ube2q2
ubiquitin-conjugating enzyme E2Q family member 2
chr14_+_30910114 0.37 ENSDART00000187166
ENSDART00000078187
foxo4
forkhead box O4
chr5_-_5243079 0.37 ENSDART00000130576
ENSDART00000164377
mvb12ba
multivesicular body subunit 12Ba
chr25_+_4581214 0.37 ENSDART00000185552
CABZ01068600.1

chr20_+_39250673 0.37 ENSDART00000153003
reps1
RALBP1 associated Eps domain containing 1
chr20_-_14781904 0.37 ENSDART00000187200
ENSDART00000179912
ENSDART00000160481
ENSDART00000026969
suco
SUN domain containing ossification factor
chr4_-_17353100 0.37 ENSDART00000134467
ENSDART00000189019
parpbp
PARP1 binding protein
chr22_-_20403194 0.37 ENSDART00000010048
map2k2a
mitogen-activated protein kinase kinase 2a
chr10_+_44719697 0.36 ENSDART00000158087
scarb1
scavenger receptor class B, member 1
chr23_-_42810664 0.36 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr3_+_26813058 0.36 ENSDART00000055537
socs1a
suppressor of cytokine signaling 1a
chr23_-_27045231 0.36 ENSDART00000187979
zgc:66440
zgc:66440
chr13_+_1100197 0.36 ENSDART00000139560
ppp3r1a
protein phosphatase 3, regulatory subunit B, alpha a
chr8_+_48966165 0.35 ENSDART00000165425
aak1a
AP2 associated kinase 1a
chr6_+_32326074 0.35 ENSDART00000042134
ENSDART00000181177
dock7
dedicator of cytokinesis 7
chr21_-_14692119 0.35 ENSDART00000123047
ehmt1b
euchromatic histone-lysine N-methyltransferase 1b
chr12_-_37449396 0.35 ENSDART00000152951
cdc42ep4b
CDC42 effector protein (Rho GTPase binding) 4b
chr8_+_7778770 0.35 ENSDART00000171325
tfe3a
transcription factor binding to IGHM enhancer 3a
chr7_-_19369002 0.35 ENSDART00000165680
ntn4
netrin 4
chr8_-_5847533 0.35 ENSDART00000192489
CABZ01102147.1

chr13_+_31550185 0.34 ENSDART00000127843
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr24_-_26622423 0.34 ENSDART00000182044
tnikb
TRAF2 and NCK interacting kinase b
chr13_-_35908275 0.34 ENSDART00000013961
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr10_+_1849874 0.34 ENSDART00000158897
ENSDART00000149956
apc
adenomatous polyposis coli
chr7_+_1579236 0.34 ENSDART00000172830
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
chr3_-_15470944 0.34 ENSDART00000185302
spns1
spinster homolog 1 (Drosophila)
chr5_+_8964926 0.34 ENSDART00000091397
ENSDART00000164535
tnksb
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b
chr15_-_14038227 0.34 ENSDART00000139068
zgc:114130
zgc:114130
chr1_-_45616470 0.34 ENSDART00000150165
atf7ip
activating transcription factor 7 interacting protein
chr22_-_16275236 0.34 ENSDART00000149051
cdc14ab
cell division cycle 14Ab
chr13_-_21739142 0.34 ENSDART00000078460
si:dkey-191g9.5
si:dkey-191g9.5
chr23_+_39346774 0.34 ENSDART00000190985
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr1_-_20970266 0.34 ENSDART00000088545
klhl2
kelch-like family member 2
chr15_-_17025212 0.34 ENSDART00000014465
hip1
huntingtin interacting protein 1
chr5_+_45139196 0.33 ENSDART00000113738
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_-_4100365 0.33 ENSDART00000142846
cux2b
cut-like homeobox 2b
chr20_-_3997531 0.33 ENSDART00000092217
ttc13
tetratricopeptide repeat domain 13
chr17_+_37511092 0.32 ENSDART00000187935
mta1
metastasis associated 1
chr4_+_55758103 0.32 ENSDART00000185964
CT583728.23

chr8_-_20138054 0.32 ENSDART00000133141
ENSDART00000147634
ENSDART00000029939
rfx2
regulatory factor X, 2 (influences HLA class II expression)
chr6_+_12503849 0.32 ENSDART00000149529
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr22_-_506522 0.32 ENSDART00000106645
ENSDART00000067637
dstyk
dual serine/threonine and tyrosine protein kinase
chr25_-_10724947 0.32 ENSDART00000184490
lrp5
low density lipoprotein receptor-related protein 5
chr15_+_45544589 0.32 ENSDART00000055978
LO018197.1

chr6_-_60104628 0.32 ENSDART00000057463
ENSDART00000169188
pmepa1
prostate transmembrane protein, androgen induced 1
chr18_-_22094102 0.31 ENSDART00000100904
pard6a
par-6 family cell polarity regulator alpha
chr13_+_23093743 0.31 ENSDART00000148034
pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr15_-_37543591 0.31 ENSDART00000180400
kmt2bb
lysine (K)-specific methyltransferase 2Bb
chr15_-_43768776 0.31 ENSDART00000170398
grm5b
glutamate receptor, metabotropic 5b
chr2_-_47620806 0.31 ENSDART00000038228
ap1s3b
adaptor-related protein complex 1, sigma 3 subunit, b
chr10_+_22890791 0.31 ENSDART00000176011
arrb2a
arrestin, beta 2a
chr22_-_35063526 0.31 ENSDART00000162211
zgc:63733
zgc:63733
chr15_+_47618221 0.31 ENSDART00000168722
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component
chr25_+_36311333 0.31 ENSDART00000190174
hist1h2a2
histone cluster 1 H2A family member 2
chr15_+_42397125 0.31 ENSDART00000169751
tiam1b
T cell lymphoma invasion and metastasis 1b
chr21_-_11054605 0.31 ENSDART00000191378
ENSDART00000084061
nedd4l
neural precursor cell expressed, developmentally down-regulated 4-like
chr17_-_8976307 0.31 ENSDART00000092113
zranb1b
zinc finger, RAN-binding domain containing 1b
chr17_+_37510834 0.30 ENSDART00000045583
mta1
metastasis associated 1
chr10_-_1625080 0.30 ENSDART00000137285
nup155
nucleoporin 155
chr14_-_7207961 0.30 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of sp3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.4 1.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 1.1 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.2 1.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 1.4 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2 0.6 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.2 0.6 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) intermediate mesoderm development(GO:0048389)
0.2 1.0 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.2 0.6 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.2 0.8 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 0.8 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 1.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.4 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 1.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.4 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1 0.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 1.1 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.7 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 0.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.3 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.1 0.4 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 0.3 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.4 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.7 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.3 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.1 0.5 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.6 GO:0006953 acute-phase response(GO:0006953)
0.1 0.7 GO:0002931 response to ischemia(GO:0002931)
0.1 0.6 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 0.4 GO:1902590 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.1 1.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.3 GO:1905132 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.5 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.7 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.3 GO:0090244 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.1 0.3 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.1 0.2 GO:2000405 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 0.3 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.2 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.1 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 1.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.5 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.3 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.1 0.5 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.3 GO:0007183 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.6 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.5 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 1.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.9 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.4 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0002693 regulation of cellular extravasation(GO:0002691) positive regulation of cellular extravasation(GO:0002693)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 1.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.5 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.8 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.4 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.6 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.5 GO:0003128 heart field specification(GO:0003128)
0.0 0.3 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0071800 podosome assembly(GO:0071800)
0.0 0.2 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.2 GO:0060876 semicircular canal formation(GO:0060876)
0.0 0.5 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.6 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.0 1.6 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.3 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.0 0.6 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:0003272 endocardial cushion formation(GO:0003272)
0.0 0.3 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0032366 intracellular sterol transport(GO:0032366)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.4 GO:0048382 mesendoderm development(GO:0048382)
0.0 0.1 GO:1902259 regulation of potassium ion transmembrane transporter activity(GO:1901016) regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.0 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 1.4 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0043268 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.3 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0021591 ventricular system development(GO:0021591)
0.0 0.1 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.0 0.7 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.4 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.9 GO:0015718 monocarboxylic acid transport(GO:0015718)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.2 0.9 GO:1990923 PET complex(GO:1990923)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.3 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 0.2 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.3 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.4 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.7 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0035101 FACT complex(GO:0035101)
0.0 1.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.7 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 1.2 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 1.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.1 GO:0000922 spindle pole(GO:0000922)
0.0 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.4 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0071253 connexin binding(GO:0071253)
0.3 0.8 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.3 2.1 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 1.2 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 1.6 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 1.1 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 1.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.3 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.1 2.0 GO:0030371 translation repressor activity(GO:0030371)
0.1 0.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.2 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.1 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.4 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.3 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0015222 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.0 1.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 1.0 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0042974 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.0 0.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.8 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.4 GO:0008200 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 1.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.1 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.0 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0034061 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.0 PID FOXO PATHWAY FoxO family signaling
0.0 2.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 0.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions