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PRJNA195909:zebrafish embryo and larva development

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Results for stat3

Z-value: 0.53

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Transcription factors associated with stat3

Gene Symbol Gene ID Gene Info
stat3
ENSDARG00000022712 signal transducer and activator of transcription 3 (acute-phase response factor)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
stat3dr11_v1_chr3_+_17030665_17030704-0.751.9e-02Click!

Activity profile of stat3 motif

Sorted Z-values of stat3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_16595177 1.14 ENSDART00000133962
si:dkey-239j18.2
si:dkey-239j18.2
chr12_-_16941319 0.97 ENSDART00000109968
zgc:174855
zgc:174855
chr12_+_16949391 0.92 ENSDART00000152635
zgc:174153
zgc:174153
chr19_+_10846182 0.86 ENSDART00000168479
apoa4a
apolipoprotein A-IV a
chr14_-_32744464 0.83 ENSDART00000075617
sox3
SRY (sex determining region Y)-box 3
chr24_-_33291784 0.81 ENSDART00000124938
si:ch1073-406l10.2
si:ch1073-406l10.2
chr23_-_10175898 0.81 ENSDART00000146185
krt5
keratin 5
chr19_+_10937932 0.77 ENSDART00000168968
si:ch73-347e22.8
si:ch73-347e22.8
chr19_+_17385561 0.76 ENSDART00000141397
ENSDART00000143913
ENSDART00000133626
rpl15
ribosomal protein L15
chr14_+_11457500 0.75 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr24_-_37568359 0.70 ENSDART00000056286
h1f0
H1 histone family, member 0
chr18_-_14860435 0.68 ENSDART00000018502
mapk12a
mitogen-activated protein kinase 12a
chr19_+_8973042 0.66 ENSDART00000039597
crabp2b
cellular retinoic acid binding protein 2, b
chr7_+_32369026 0.66 ENSDART00000169588
lgr4
leucine-rich repeat containing G protein-coupled receptor 4
chr21_+_35215810 0.66 ENSDART00000135256
ubtd2
ubiquitin domain containing 2
chr23_+_44732863 0.65 ENSDART00000160044
ENSDART00000172268
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr9_+_40825065 0.65 ENSDART00000137673
si:dkey-95p16.2
si:dkey-95p16.2
chr17_+_10318071 0.62 ENSDART00000161844
foxa1
forkhead box A1
chr5_-_40734045 0.62 ENSDART00000010896
isl1
ISL LIM homeobox 1
chr8_+_32755688 0.62 ENSDART00000137897
hmcn2
hemicentin 2
chr21_-_34844059 0.61 ENSDART00000136402
zgc:56585
zgc:56585
chr14_+_7932973 0.59 ENSDART00000109941
cxxc5b
CXXC finger protein 5b
chr11_-_762721 0.58 ENSDART00000166465
syn2b
synapsin IIb
chr14_+_11395383 0.57 ENSDART00000106657
glod5
glyoxalase domain containing 5
chr1_+_5402476 0.56 ENSDART00000040204
tuba8l2
tubulin, alpha 8 like 2
chr17_-_10838434 0.56 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr23_-_19715799 0.54 ENSDART00000142072
ENSDART00000032744
ENSDART00000131860
rpl10
ribosomal protein L10
chr11_-_17964525 0.52 ENSDART00000018948
cishb
cytokine inducible SH2-containing protein b
chr16_-_31717851 0.50 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr10_-_3332362 0.50 ENSDART00000007577
ENSDART00000055140
tor4aa
torsin family 4, member Aa
chr9_+_26103814 0.50 ENSDART00000026011
efnb2a
ephrin-B2a
chr3_-_39488482 0.49 ENSDART00000135192
zgc:100868
zgc:100868
chr20_-_35841570 0.49 ENSDART00000037855
tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr7_+_48319916 0.48 ENSDART00000052122
crabp1b
cellular retinoic acid binding protein 1b
chr6_+_55357188 0.47 ENSDART00000158219
pltp
phospholipid transfer protein
chr4_+_47257854 0.46 ENSDART00000173868
crestin
crestin
chr16_+_42772678 0.45 ENSDART00000155575
si:ch211-135n15.2
si:ch211-135n15.2
chr7_+_32369463 0.45 ENSDART00000180544
lgr4
leucine-rich repeat containing G protein-coupled receptor 4
chr21_-_5879897 0.44 ENSDART00000184034
rpl35
ribosomal protein L35
chr1_-_9114936 0.44 ENSDART00000163624
ENSDART00000132910
si:ch211-14k19.8
vap
si:ch211-14k19.8
vascular associated protein
chr19_+_10845953 0.43 ENSDART00000157589
apoa4a
apolipoprotein A-IV a
chr18_-_3166726 0.42 ENSDART00000165002
aqp11
aquaporin 11
chr13_+_39532050 0.42 ENSDART00000019379
marveld1
MARVEL domain containing 1
chr23_+_42414652 0.42 ENSDART00000171119
cyp2aa9
cytochrome P450, family 2, subfamily AA, polypeptide 9
chr14_+_6159356 0.42 ENSDART00000157730
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr16_-_31718013 0.41 ENSDART00000190716
rbp5
retinol binding protein 1a, cellular
chr1_-_10071422 0.41 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr7_-_28696556 0.40 ENSDART00000148822
adgrg1
adhesion G protein-coupled receptor G1
chr16_+_31922065 0.40 ENSDART00000131661
ENSDART00000144194
ENSDART00000145510
rps9
ribosomal protein S9
chr6_+_43015916 0.39 ENSDART00000064888
tcta
T cell leukemia translocation altered
chr6_-_40573221 0.39 ENSDART00000157203
ENSDART00000154951
tomm6
translocase of outer mitochondrial membrane 6 homolog (yeast)
chr12_-_19346678 0.39 ENSDART00000044860
maff
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr1_-_26398361 0.39 ENSDART00000160183
ppa2
pyrophosphatase (inorganic) 2
chr20_+_52458765 0.39 ENSDART00000057980
tsta3
tissue specific transplantation antigen P35B
chr17_+_40989973 0.38 ENSDART00000160049
mrpl33
mitochondrial ribosomal protein L33
chr24_+_16149514 0.37 ENSDART00000152087
si:dkey-118j18.2
si:dkey-118j18.2
chr19_+_43359075 0.37 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
yrk
Yes-related kinase
chr21_+_8341774 0.37 ENSDART00000129749
ENSDART00000055325
ENSDART00000133804
psmb7
proteasome subunit beta 7
chr18_-_28938912 0.37 ENSDART00000136201
si:ch211-174j14.2
si:ch211-174j14.2
chr6_+_22679610 0.37 ENSDART00000102701
zmp:0000000634
zmp:0000000634
chr18_-_15373620 0.37 ENSDART00000031752
rfx4
regulatory factor X, 4
chr7_-_22941472 0.36 ENSDART00000190334
tnfsf10l
TNF superfamily member 10, like
chr1_+_19535144 0.36 ENSDART00000103089
si:dkey-245p14.4
si:dkey-245p14.4
chr20_+_32497260 0.36 ENSDART00000145175
ENSDART00000132921
si:ch73-257c13.2
si:ch73-257c13.2
chr21_-_30545121 0.35 ENSDART00000019199
rab39ba
RAB39B, member RAS oncogene family a
chr5_+_24179307 0.35 ENSDART00000051552
mpdu1a
mannose-P-dolichol utilization defect 1a
chr16_+_54513267 0.35 ENSDART00000161923
CABZ01088508.1

chr3_+_4502066 0.35 ENSDART00000088610
rangap1a
RAN GTPase activating protein 1a
chr24_+_16149251 0.35 ENSDART00000188289
si:dkey-118j18.2
si:dkey-118j18.2
chr10_+_13209580 0.34 ENSDART00000000887
ENSDART00000136932
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr1_-_51734524 0.34 ENSDART00000109640
ENSDART00000122628
junba
JunB proto-oncogene, AP-1 transcription factor subunit a
chr13_-_37608441 0.34 ENSDART00000140230
zgc:123068
zgc:123068
chr21_+_45626136 0.33 ENSDART00000158742
irf1b
interferon regulatory factor 1b
chr21_-_34844316 0.33 ENSDART00000029708
zgc:56585
zgc:56585
chr4_-_12323228 0.33 ENSDART00000081089
il17ra1a
interleukin 17 receptor A1a
chr16_+_31921812 0.33 ENSDART00000176928
ENSDART00000193733
rps9
ribosomal protein S9
chr1_-_46981134 0.32 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr1_-_55008882 0.32 ENSDART00000083572
zgc:136864
zgc:136864
chr21_+_19834072 0.32 ENSDART00000147555
ccdc80l2
coiled-coil domain containing 80 like 2
chr2_+_26288301 0.32 ENSDART00000017668
ptbp1a
polypyrimidine tract binding protein 1a
chr13_+_14976108 0.32 ENSDART00000011520
noto
notochord homeobox
chr11_+_11200550 0.31 ENSDART00000181339
ENSDART00000187116
myom2a
myomesin 2a
chr16_-_1502699 0.30 ENSDART00000187189
sim1a
single-minded family bHLH transcription factor 1a
chr1_-_50791280 0.29 ENSDART00000181224
CABZ01031870.1

chr13_+_36613359 0.29 ENSDART00000140598
si:ch211-67f24.7
si:ch211-67f24.7
chr10_-_4375190 0.28 ENSDART00000016102
CABZ01073795.1

chr24_-_37877743 0.28 ENSDART00000105658
tmem204
transmembrane protein 204
chr17_-_6730247 0.28 ENSDART00000031091
vsnl1b
visinin-like 1b
chr8_+_27807974 0.28 ENSDART00000078509
capza1b
capping protein (actin filament) muscle Z-line, alpha 1b
chr3_+_26734162 0.28 ENSDART00000114552
si:dkey-202l16.5
si:dkey-202l16.5
chr22_-_372723 0.28 ENSDART00000112895
FNDC10
si:zfos-1324h11.5
chr21_-_27338639 0.28 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr18_-_44888375 0.27 ENSDART00000160506
si:ch211-71n6.4
si:ch211-71n6.4
chr14_+_6159162 0.27 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr19_-_41405187 0.27 ENSDART00000038038
ENSDART00000172350
sem1
SEM1, 26S proteasome complex subunit
chr5_+_15819651 0.27 ENSDART00000081230
ENSDART00000186969
ENSDART00000134206
hspb8
heat shock protein b8
chr2_+_20967673 0.26 ENSDART00000057174
arpc5a
actin related protein 2/3 complex, subunit 5A
chr23_+_5524247 0.26 ENSDART00000189679
ENSDART00000083622
tead3a
TEA domain family member 3 a
chr6_+_6491013 0.26 ENSDART00000140827
bcl11ab
B cell CLL/lymphoma 11Ab
chr6_-_35106425 0.26 ENSDART00000165139
nos1apa
nitric oxide synthase 1 (neuronal) adaptor protein a
chr18_+_6054816 0.26 ENSDART00000113668
si:ch73-386h18.1
si:ch73-386h18.1
chr9_-_23922011 0.26 ENSDART00000145734
col6a3
collagen, type VI, alpha 3
chr16_+_40560622 0.26 ENSDART00000038294
tp53inp1
tumor protein p53 inducible nuclear protein 1
chr2_+_10766744 0.26 ENSDART00000015379
gfi1aa
growth factor independent 1A transcription repressor a
chr9_-_23922778 0.25 ENSDART00000135769
col6a3
collagen, type VI, alpha 3
chr16_-_12809873 0.25 ENSDART00000146997
ENSDART00000178291
ENSDART00000007842
isoc2
isochorismatase domain containing 2
chr24_-_18477672 0.25 ENSDART00000126928
ENSDART00000158393
si:dkey-73n8.3
si:dkey-73n8.3
chr4_-_1818315 0.25 ENSDART00000067433
ube2nb
ubiquitin-conjugating enzyme E2Nb
chr22_-_16180467 0.25 ENSDART00000171331
ENSDART00000185607
vcam1b
vascular cell adhesion molecule 1b
chr16_-_45398408 0.25 ENSDART00000004052
rgl2
ral guanine nucleotide dissociation stimulator-like 2
chr7_+_27277236 0.24 ENSDART00000185161
sox6
SRY (sex determining region Y)-box 6
chr12_+_23875318 0.24 ENSDART00000152869
svila
supervillin a
chr14_+_7452302 0.24 ENSDART00000130388
gfra3
GDNF family receptor alpha 3
chr8_+_54055390 0.24 ENSDART00000102696
magi1a
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr2_-_47431205 0.24 ENSDART00000014350
ENSDART00000038828
pax3a
paired box 3a
chr5_+_29820266 0.23 ENSDART00000146331
ENSDART00000098315
f11r.2
F11 receptor, tandem duplicate 2
chr13_-_49819027 0.23 ENSDART00000067824
b3galnt2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr15_+_5360407 0.23 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr17_-_31308658 0.23 ENSDART00000124505
bahd1
bromo adjacent homology domain containing 1
chr2_+_4402765 0.23 ENSDART00000159525
bambib
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b
chr14_-_30747686 0.23 ENSDART00000008373
fosl1a
FOS-like antigen 1a
chr7_+_58686860 0.23 ENSDART00000052332
penkb
proenkephalin b
chr25_-_21822426 0.22 ENSDART00000151993
zgc:158222
zgc:158222
chr9_+_51265283 0.22 ENSDART00000137426
gcgb
glucagon b
chr15_+_23550890 0.22 ENSDART00000009796
ENSDART00000152720
MARK4
si:dkey-31m14.7
chr11_+_16040680 0.22 ENSDART00000157703
agtrap
angiotensin II receptor-associated protein
chr3_+_59899452 0.21 ENSDART00000064311
arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
chr24_+_31361407 0.21 ENSDART00000162668
cremb
cAMP responsive element modulator b
chr14_-_28567845 0.20 ENSDART00000126095
insb
preproinsulin b
chr19_+_712127 0.20 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
fhod3a
formin homology 2 domain containing 3a
chr3_-_35541378 0.20 ENSDART00000183075
ENSDART00000022147
ndufab1b
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1b
chr9_+_34221997 0.20 ENSDART00000028617
mpc2
mitochondrial pyruvate carrier 2
chr19_+_47783137 0.20 ENSDART00000024777
ENSDART00000158979
c19h1orf109
c19h1orf109 homolog (H. sapiens)
chr4_+_37406676 0.20 ENSDART00000130981
si:ch73-134f24.1
si:ch73-134f24.1
chr20_+_27020201 0.20 ENSDART00000126919
ENSDART00000016014
chga
chromogranin A
chr16_-_15387459 0.19 ENSDART00000053754
has2
hyaluronan synthase 2
chr22_-_12890921 0.19 ENSDART00000146484
nab1a
NGFI-A binding protein 1a (EGR1 binding protein 1)
chr2_-_13216269 0.19 ENSDART00000149947
bcl2b
BCL2, apoptosis regulator b
chr2_+_17181777 0.19 ENSDART00000112063
ptger4c
prostaglandin E receptor 4 (subtype EP4) c
chr11_-_6265574 0.19 ENSDART00000181974
ENSDART00000104405
ccl25b
chemokine (C-C motif) ligand 25b
chr8_+_26141680 0.19 ENSDART00000078334
celsr3
cadherin, EGF LAG seven-pass G-type receptor 3
chr4_+_57580303 0.19 ENSDART00000166492
ENSDART00000103025
ENSDART00000170786
il17ra1b
il17ra2
interleukin 17 receptor A1b
interleukin 17 receptor A2
chr9_+_20853894 0.19 ENSDART00000003648
wdr3
WD repeat domain 3
chr7_-_33960170 0.18 ENSDART00000180766
skor1a
SKI family transcriptional corepressor 1a
chr5_-_26466169 0.18 ENSDART00000144035
arvcfb
ARVCF, delta catenin family member b
chr8_+_23152244 0.18 ENSDART00000036801
ENSDART00000184298
slc17a9a
solute carrier family 17 (vesicular nucleotide transporter), member 9a
chr24_-_26383978 0.18 ENSDART00000031426
skilb
SKI-like proto-oncogene b
chr11_+_4026229 0.18 ENSDART00000041417
camk1b
calcium/calmodulin-dependent protein kinase Ib
chr7_+_25053331 0.18 ENSDART00000173998
si:dkey-23i12.7
si:dkey-23i12.7
chr16_+_38394371 0.18 ENSDART00000137954
cd83
CD83 molecule
chr24_+_42948 0.17 ENSDART00000122785
tmx3b
thioredoxin related transmembrane protein 3b
chr18_-_16801033 0.17 ENSDART00000100100
admb
adrenomedullin b
chr4_+_49322310 0.17 ENSDART00000184154
ENSDART00000167162
BX942819.1

chr22_+_5851122 0.17 ENSDART00000082044
zmp:0000001161
zmp:0000001161
chr16_-_19254323 0.17 ENSDART00000138744
dnah11
dynein, axonemal, heavy chain 11
chr16_+_32059785 0.16 ENSDART00000134459
si:dkey-40m6.8
si:dkey-40m6.8
chr13_+_52061034 0.16 ENSDART00000170383
CABZ01089777.1

chr5_+_20103085 0.16 ENSDART00000079424
si:rp71-1c23.3
si:rp71-1c23.3
chr20_+_18993452 0.16 ENSDART00000025509
tdh
L-threonine dehydrogenase
chr6_+_11989537 0.16 ENSDART00000190817
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr20_+_10166297 0.16 ENSDART00000141877
kcnk10a
potassium channel, subfamily K, member 10a
chr5_-_23118290 0.16 ENSDART00000132857
uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr6_-_55958705 0.16 ENSDART00000155963
eya2
EYA transcriptional coactivator and phosphatase 2
chr3_-_22829710 0.16 ENSDART00000055659
cyb561
cytochrome b561
chr24_-_26304386 0.15 ENSDART00000175416
otos
otospiralin
chr1_-_10647484 0.15 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr11_+_16040517 0.15 ENSDART00000111284
agtrap
angiotensin II receptor-associated protein
chr9_+_13985567 0.15 ENSDART00000102296
cd28
CD28 molecule
chr19_+_5418006 0.15 ENSDART00000132874
eif1b
eukaryotic translation initiation factor 1B
chr4_+_76637548 0.15 ENSDART00000133799
ms4a17a.9
membrane-spanning 4-domains, subfamily A, member 17A.9
chr8_-_30979494 0.15 ENSDART00000138959
si:ch211-251j10.3
si:ch211-251j10.3
chr6_-_34220641 0.14 ENSDART00000102391
dmrt2b
doublesex and mab-3 related transcription factor 2b
chr18_+_37219140 0.14 ENSDART00000088247
qpctla
glutaminyl-peptide cyclotransferase-like a
chr22_+_20427170 0.14 ENSDART00000136744
foxq2
forkhead box Q2
chr15_-_3282220 0.14 ENSDART00000092942
slc25a15a
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr11_-_1024483 0.14 ENSDART00000017551
slc6a1b
solute carrier family 6 (neurotransmitter transporter), member 1b
chr4_+_76735113 0.14 ENSDART00000075602
ms4a17a.6
membrane-spanning 4-domains, subfamily A, member 17A.6
chr24_-_26485098 0.14 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eif5a
eukaryotic translation initiation factor 5A
chr3_-_16039619 0.14 ENSDART00000143324
spsb3a
splA/ryanodine receptor domain and SOCS box containing 3a
chr5_-_49012569 0.14 ENSDART00000184690
si:dkey-172m14.2
si:dkey-172m14.2
chr20_+_34582276 0.14 ENSDART00000185185
si:ch211-242b18.1
si:ch211-242b18.1
chr10_-_20105553 0.13 ENSDART00000184502
pbdc1
polysaccharide biosynthesis domain containing 1
chr1_-_10669436 0.13 ENSDART00000152421
si:dkey-31e10.5
si:dkey-31e10.5
chr20_-_19858936 0.13 ENSDART00000161579
ptk2bb
protein tyrosine kinase 2 beta, b
chr6_+_41099787 0.13 ENSDART00000186884
fkbp5
FK506 binding protein 5
chr19_+_10587307 0.13 ENSDART00000131225
si:dkey-211g8.4
si:dkey-211g8.4
chr17_+_25397070 0.13 ENSDART00000164254
zgc:154055
zgc:154055
chr23_+_34005792 0.13 ENSDART00000132668
si:ch211-207e14.4
si:ch211-207e14.4
chr1_-_10647307 0.12 ENSDART00000103548
si:dkey-31e10.1
si:dkey-31e10.1
chr18_+_19975787 0.12 ENSDART00000138103
skor1b
SKI family transcriptional corepressor 1b
chr19_+_7597936 0.12 ENSDART00000142955
s100s
S100 calcium binding protein S
chr19_-_17385548 0.12 ENSDART00000162383
nkiras1
NFKB inhibitor interacting Ras-like 1
chr15_-_29510074 0.11 ENSDART00000184070
BX324227.3

chr2_-_37896646 0.11 ENSDART00000075931
hbl1
hexose-binding lectin 1
chr5_+_28271412 0.11 ENSDART00000031727
vamp8
vesicle-associated membrane protein 8 (endobrevin)
chr18_-_21177674 0.11 ENSDART00000060175
si:dkey-12e7.4
si:dkey-12e7.4
chr4_+_72668095 0.11 ENSDART00000182282
ENSDART00000162637
CABZ01054391.1

chr4_+_45458619 0.11 ENSDART00000124892
si:dkey-256i11.3
si:dkey-256i11.3
chr19_+_15443353 0.11 ENSDART00000135923
lin28a
lin-28 homolog A (C. elegans)
chr3_+_25154078 0.10 ENSDART00000156973
si:ch211-256m1.8
si:ch211-256m1.8

Network of associatons between targets according to the STRING database.

First level regulatory network of stat3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.2 0.7 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 0.5 GO:1990403 embryonic brain development(GO:1990403)
0.2 0.5 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.2 0.5 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.1 0.4 GO:0072020 proximal straight tubule development(GO:0072020)
0.1 0.6 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.5 GO:0007412 axon target recognition(GO:0007412)
0.1 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.5 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.6 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 0.9 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.1 0.3 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.1 0.4 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.3 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.2 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.1 0.2 GO:0003091 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) hyaluronan biosynthetic process(GO:0030213)
0.1 0.2 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.1 0.2 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
0.1 0.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.7 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.4 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 0.8 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.1 GO:0018199 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.0 0.6 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.3 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.3 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 0.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.8 GO:0043049 otic placode formation(GO:0043049)
0.0 0.2 GO:0050936 xanthophore differentiation(GO:0050936)
0.0 0.1 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.4 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.2 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.4 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.1 GO:0070254 mucus secretion(GO:0070254)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.0 GO:0044038 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0045095 keratin filament(GO:0045095)
0.1 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.6 GO:0001772 immunological synapse(GO:0001772)
0.1 0.6 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.3 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.0 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 3.0 GO:0005764 lysosome(GO:0005764)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.6 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 1.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.9 GO:0016918 retinal binding(GO:0016918)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.3 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 0.2 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 2.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 2.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism