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PRJNA195909:zebrafish embryo and larva development

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Results for stat4

Z-value: 0.81

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Transcription factors associated with stat4

Gene Symbol Gene ID Gene Info
stat4
ENSDARG00000028731 signal transducer and activator of transcription 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
stat4dr11_v1_chr9_+_41156818_411568180.422.6e-01Click!

Activity profile of stat4 motif

Sorted Z-values of stat4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25777425 1.54 ENSDART00000021620
cldnd
claudin d
chr6_+_41503854 1.28 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr1_-_6085750 1.21 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr21_-_32060993 1.13 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr5_+_36768674 1.11 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr17_-_12498096 1.04 ENSDART00000149551
ENSDART00000105215
ENSDART00000191207
emilin1b
elastin microfibril interfacer 1b
chr6_+_21005725 1.02 ENSDART00000041370
cx44.2
connexin 44.2
chr14_-_32631519 0.95 ENSDART00000167282
ENSDART00000052938
atp11c
ATPase phospholipid transporting 11C
chr15_+_25489406 0.88 ENSDART00000162482
zgc:152863
zgc:152863
chr8_-_25033681 0.85 ENSDART00000003493
nfyal
nuclear transcription factor Y, alpha, like
chr21_+_39197418 0.83 ENSDART00000076000
cpdb
carboxypeptidase D, b
chr2_-_16449504 0.81 ENSDART00000144801
atr
ATR serine/threonine kinase
chr19_-_3821678 0.79 ENSDART00000169639
si:dkey-206d17.12
si:dkey-206d17.12
chr1_+_12195700 0.75 ENSDART00000040307
tdrd7a
tudor domain containing 7 a
chr3_-_31879201 0.75 ENSDART00000076189
zgc:171779
zgc:171779
chr4_+_16827390 0.73 ENSDART00000113344
kiss2
kisspeptin 2
chr8_-_11067079 0.73 ENSDART00000181986
dennd2c
DENN/MADD domain containing 2C
chr9_-_55946377 0.72 ENSDART00000161536
ENSDART00000169432
SH3RF3
si:ch211-124n19.2
chr5_-_57624425 0.69 ENSDART00000167892
zgc:193711
zgc:193711
chr16_-_22585289 0.69 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr8_+_41048501 0.69 ENSDART00000123288
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr7_-_50764714 0.67 ENSDART00000110283
iqgap1
IQ motif containing GTPase activating protein 1
chr9_+_44994214 0.67 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr15_+_20529197 0.67 ENSDART00000060935
ENSDART00000137926
ENSDART00000140087
tnfaip1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr9_-_27738110 0.67 ENSDART00000060347
crygs2
crystallin, gamma S2
chr18_-_20444296 0.66 ENSDART00000132993
kif23
kinesin family member 23
chr12_+_33403694 0.65 ENSDART00000124083
fasn
fatty acid synthase
chr21_+_39197628 0.64 ENSDART00000113607
cpdb
carboxypeptidase D, b
chr24_+_37484661 0.64 ENSDART00000165125
ENSDART00000109221
wdr90
WD repeat domain 90
chr6_+_2195625 0.64 ENSDART00000155659
acvr1bb
activin A receptor type 1Bb
chr17_+_30591287 0.61 ENSDART00000154243
si:dkey-190l8.2
si:dkey-190l8.2
chr23_+_4350897 0.60 ENSDART00000190593
mybl2a
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr24_-_20599781 0.58 ENSDART00000179664
ENSDART00000141823
zbtb47b
zinc finger and BTB domain containing 47b
chr19_-_46091497 0.58 ENSDART00000178772
ENSDART00000167255
ptdss1b
si:dkey-108k24.2
phosphatidylserine synthase 1b
si:dkey-108k24.2
chr7_-_31781339 0.58 ENSDART00000142666
nap1l4b
nucleosome assembly protein 1-like 4b
chr3_-_10621391 0.58 ENSDART00000058834
map2k4a
mitogen-activated protein kinase kinase 4a
chr23_-_24483311 0.57 ENSDART00000185793
ENSDART00000109248
spen
spen family transcriptional repressor
chr2_+_42005475 0.57 ENSDART00000056461
gbp2
guanylate binding protein 2
chr6_-_24392426 0.56 ENSDART00000163965
brdt
bromodomain, testis-specific
chr7_-_24875421 0.56 ENSDART00000173920
adad2
adenosine deaminase domain containing 2
chr19_+_40379771 0.54 ENSDART00000017917
ENSDART00000110699
vps50
vps50
VPS50 EARP/GARPII complex subunit
VPS50 EARP/GARPII complex subunit
chr9_-_16062938 0.53 ENSDART00000099479
crfb4
cytokine receptor family member b4
chr9_+_38502524 0.53 ENSDART00000087229
lmln
leishmanolysin-like (metallopeptidase M8 family)
chr22_-_22130623 0.53 ENSDART00000113168
CU855878.1

chr21_+_20901505 0.52 ENSDART00000132741
c7b
complement component 7b
chr5_-_41984298 0.52 ENSDART00000189535
ncor1
nuclear receptor corepressor 1
chr3_-_3439150 0.52 ENSDART00000021286
A2ML1 (1 of many)
si:dkey-46g23.5
chr23_+_19558574 0.51 ENSDART00000137811
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr7_-_26497947 0.51 ENSDART00000058910
sox19b
SRY (sex determining region Y)-box 19b
chr19_+_38168006 0.51 ENSDART00000087662
ENSDART00000177759
phf14
PHD finger protein 14
chr16_+_4133519 0.51 ENSDART00000174521
ENSDART00000175718
mtf1
metal-regulatory transcription factor 1
chr21_-_3613702 0.49 ENSDART00000139194
dym
dymeclin
chr10_+_20392083 0.49 ENSDART00000166867
r3hcc1
R3H domain and coiled-coil containing 1
chr25_+_11281970 0.48 ENSDART00000180094
AKAP13
si:dkey-187e18.1
chr23_-_25779995 0.48 ENSDART00000110670
si:dkey-21c19.3
si:dkey-21c19.3
chr12_-_26383242 0.48 ENSDART00000152941
usp54b
ubiquitin specific peptidase 54b
chr1_+_12177195 0.47 ENSDART00000146842
ENSDART00000142081
stra6l
STRA6-like
chr7_+_38770167 0.45 ENSDART00000190827
arhgap1
Rho GTPase activating protein 1
chr3_-_40933415 0.45 ENSDART00000055201
foxk1
forkhead box K1
chr5_-_40190949 0.45 ENSDART00000175588
wdfy3
WD repeat and FYVE domain containing 3
chr25_+_32390794 0.45 ENSDART00000012600
galk2
galactokinase 2
chr8_+_47897734 0.44 ENSDART00000140266
mfn2
mitofusin 2
chr11_-_18791834 0.44 ENSDART00000156431
pfkfb2b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr12_-_35393211 0.44 ENSDART00000137139
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr2_+_25868404 0.43 ENSDART00000143517
ENSDART00000187743
slc7a14a
solute carrier family 7, member 14a
chr16_-_2390931 0.43 ENSDART00000149463
hace1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr18_-_29977431 0.42 ENSDART00000135357
si:ch211-220f16.2
si:ch211-220f16.2
chr7_+_45963767 0.42 ENSDART00000163098
pop4
POP4 homolog, ribonuclease P/MRP subunit
chr2_+_42005217 0.42 ENSDART00000143562
gbp2
guanylate binding protein 2
chr16_-_27564256 0.41 ENSDART00000078297
zgc:153215
zgc:153215
chr17_+_24111392 0.41 ENSDART00000180123
ENSDART00000182787
ENSDART00000189752
ENSDART00000184940
ENSDART00000185363
ENSDART00000064067
ehbp1
EH domain binding protein 1
chr21_+_21791343 0.41 ENSDART00000151654
neu3.1
sialidase 3 (membrane sialidase), tandem duplicate 1
chr8_+_44613135 0.40 ENSDART00000063392
lsm1
LSM1, U6 small nuclear RNA associated
chr15_-_9631592 0.40 ENSDART00000171214
nars2
asparaginyl-tRNA synthetase 2, mitochondrial
chr15_-_18200358 0.40 ENSDART00000158569
si:ch211-247l8.8
si:ch211-247l8.8
chr18_-_3527686 0.40 ENSDART00000169049
capn5a
calpain 5a
chr11_+_41459408 0.39 ENSDART00000182285
park7
parkinson protein 7
chr16_-_4610255 0.39 ENSDART00000081852
ENSDART00000123253
ENSDART00000127554
ENSDART00000029485
arnt
aryl hydrocarbon receptor nuclear translocator
chr9_+_6934491 0.39 ENSDART00000114323
mfsd9
major facilitator superfamily domain containing 9
chr16_+_9713850 0.38 ENSDART00000164103
ecm1b
extracellular matrix protein 1b
chr1_-_36770883 0.38 ENSDART00000167831
prmt9
protein arginine methyltransferase 9
chr22_-_20838011 0.38 ENSDART00000186056
dot1l
DOT1-like histone H3K79 methyltransferase
chr12_+_28888975 0.38 ENSDART00000076362
phkg2
phosphorylase kinase, gamma 2 (testis)
chr18_-_3527988 0.37 ENSDART00000157669
capn5a
calpain 5a
chr6_+_18423402 0.37 ENSDART00000159747
rab11fip4b
RAB11 family interacting protein 4 (class II) b
chr5_+_50371951 0.37 ENSDART00000184488
ENSDART00000171295
slf1
SMC5-SMC6 complex localization factor 1
chr6_+_7322587 0.36 ENSDART00000065500
abcc4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr16_-_11859309 0.36 ENSDART00000145754
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr12_-_17602958 0.36 ENSDART00000134690
ENSDART00000028090
eif2ak1
eukaryotic translation initiation factor 2-alpha kinase 1
chr3_-_61377127 0.36 ENSDART00000155932
si:dkey-111k8.2
si:dkey-111k8.2
chr10_+_29770120 0.36 ENSDART00000100032
ENSDART00000193205
hyou1
hypoxia up-regulated 1
chr1_-_18585046 0.35 ENSDART00000147228
fam114a1
family with sequence similarity 114, member A1
chr22_-_13165186 0.35 ENSDART00000105762
ahr2
aryl hydrocarbon receptor 2
chr2_+_49246099 0.35 ENSDART00000179089
sema6ba
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr1_+_42225060 0.35 ENSDART00000138740
ENSDART00000101306
ctnna2
catenin (cadherin-associated protein), alpha 2
chr6_+_32834007 0.35 ENSDART00000157353
cyldl
cylindromatosis (turban tumor syndrome), like
chr6_-_30689126 0.34 ENSDART00000065211
pars2
prolyl-tRNA synthetase 2, mitochondrial
chr10_+_8401929 0.34 ENSDART00000059028
hvcn1
hydrogen voltage-gated channel 1
chr5_+_54280135 0.34 ENSDART00000170218
ENSDART00000166050
rangrf
RAN guanine nucleotide release factor
chr6_+_18367388 0.34 ENSDART00000163394
dgke
diacylglycerol kinase, epsilon
chr23_+_1216215 0.33 ENSDART00000165957
utrn
utrophin
chr6_+_4387150 0.33 ENSDART00000181283
rbm26
RNA binding motif protein 26
chr16_+_16266428 0.33 ENSDART00000188433
setd2
SET domain containing 2
chr14_+_45970033 0.33 ENSDART00000047716
fermt3b
fermitin family member 3b
chr18_-_21047580 0.32 ENSDART00000010189
igf1ra
insulin-like growth factor 1a receptor
chr14_-_33278084 0.32 ENSDART00000132850
stard14
START domain containing 14
chr15_-_31508221 0.31 ENSDART00000121464
si:dkey-1m11.5
si:dkey-1m11.5
chr22_-_11078988 0.31 ENSDART00000126664
ENSDART00000006927
use1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr11_+_36777613 0.30 ENSDART00000065644
ENSDART00000158151
parapinopsinb
parapinopsin b
chr25_-_36263115 0.30 ENSDART00000143046
ENSDART00000139002
dus2
dihydrouridine synthase 2
chr19_-_17658160 0.30 ENSDART00000151766
ENSDART00000170790
ENSDART00000186678
ENSDART00000188045
ENSDART00000176980
ENSDART00000166313
ENSDART00000188589
thrb
thyroid hormone receptor beta
chr2_+_29257942 0.30 ENSDART00000184362
ENSDART00000025562
cdh18a
cadherin 18, type 2a
chr11_+_33426510 0.30 ENSDART00000163106
cntnap5l
contactin associated protein-like 5 like
chr3_-_31057624 0.29 ENSDART00000152901
armc5
armadillo repeat containing 5
chr18_-_46135927 0.29 ENSDART00000134537
ENSDART00000191481
SPTBN4
si:ch73-262h23.4
chr12_+_23371542 0.28 ENSDART00000078896
waca
WW domain containing adaptor with coiled-coil a
chr19_-_22843480 0.28 ENSDART00000052503
nudcd1
NudC domain containing 1
chr3_-_43954971 0.28 ENSDART00000167159
ENSDART00000189315
ubfd1
ubiquitin family domain containing 1
chr19_+_1673599 0.28 ENSDART00000163127
klhl7
kelch-like family member 7
chr3_-_32275975 0.28 ENSDART00000178448
cpt1cb
carnitine palmitoyltransferase 1Cb
chr15_+_33691455 0.28 ENSDART00000170329
hdac12
histone deacetylase 12
chr22_-_9861531 0.27 ENSDART00000193197
si:dkey-253d23.2
si:dkey-253d23.2
chr22_+_15973122 0.27 ENSDART00000144545
rc3h1a
ring finger and CCCH-type domains 1a
chr22_-_20514043 0.27 ENSDART00000088890
atp8b3
ATPase phospholipid transporting 8B3
chr7_+_29065915 0.27 ENSDART00000136657
vrk3
vaccinia related kinase 3
chr3_-_32170850 0.26 ENSDART00000055307
ENSDART00000157366
tnnt1
troponin T type 1 (skeletal, slow)
chr21_-_22715297 0.26 ENSDART00000065548
c1qb
complement component 1, q subcomponent, B chain
chr7_+_32693890 0.26 ENSDART00000121972
slc39a13
solute carrier family 39 (zinc transporter), member 13
chr21_+_39100289 0.25 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr3_+_36646054 0.24 ENSDART00000170013
ENSDART00000159948
gspt1l
G1 to S phase transition 1, like
chr6_-_8377055 0.24 ENSDART00000131513
ilf3a
interleukin enhancer binding factor 3a
chr11_+_6431133 0.23 ENSDART00000190742
FO904935.1

chr6_+_12462079 0.23 ENSDART00000192029
ENSDART00000065385
nr4a2b
nuclear receptor subfamily 4, group A, member 2b
chr17_+_12767640 0.23 ENSDART00000112469
ENSDART00000154984
ENSDART00000124584
ENSDART00000193647
ENSDART00000179686
ralgapa1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr2_+_2957515 0.23 ENSDART00000160715
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr11_-_11882982 0.23 ENSDART00000190853
wipf2a
WAS/WASL interacting protein family, member 2a
chr2_-_15031858 0.22 ENSDART00000191478
hccsa.1
holocytochrome c synthase a
chr9_-_37749973 0.22 ENSDART00000087663
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr14_-_45595711 0.22 ENSDART00000074038
scyl1
SCY1-like, kinase-like 1
chr5_-_37959874 0.21 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr20_+_37294112 0.21 ENSDART00000076293
ENSDART00000140450
cx23
connexin 23
chr24_+_5208171 0.21 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
si:ch73-206p6.1
chr23_-_31763753 0.21 ENSDART00000053399
aldh8a1
aldehyde dehydrogenase 8 family, member A1
chr19_-_808265 0.21 ENSDART00000082454
glmp
glycosylated lysosomal membrane protein
chr22_-_11493236 0.21 ENSDART00000002691
tspan7b
tetraspanin 7b
chr3_+_40289418 0.20 ENSDART00000017304
cpsf4
cleavage and polyadenylation specific factor 4
chr11_-_6420917 0.19 ENSDART00000193717
FO681393.2

chr6_-_11800427 0.19 ENSDART00000126243
march7
membrane-associated ring finger (C3HC4) 7
chr19_-_10286228 0.19 ENSDART00000027316
cnot3b
CCR4-NOT transcription complex, subunit 3b
chr21_+_6397463 0.19 ENSDART00000136539
si:ch211-225g23.1
si:ch211-225g23.1
chr17_-_26604549 0.19 ENSDART00000174773
fam149b1
family with sequence similarity 149, member B1
chr12_+_30367079 0.18 ENSDART00000190112
ccdc186
si:ch211-225b10.4
chr8_-_20838342 0.18 ENSDART00000141345
si:ch211-133l5.7
si:ch211-133l5.7
chr14_+_28473173 0.18 ENSDART00000017075
xiap
X-linked inhibitor of apoptosis
chr8_+_41413919 0.18 ENSDART00000142590
si:ch211-152p23.2
si:ch211-152p23.2
chr16_-_10071886 0.18 ENSDART00000136168
ENSDART00000130382
ptpn2a
protein tyrosine phosphatase, non-receptor type 2, a
chr2_-_42035250 0.17 ENSDART00000056460
ENSDART00000140788
gbp1
guanylate binding protein 1
chr23_-_33558161 0.17 ENSDART00000018301
itga5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr6_-_40697585 0.17 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr7_+_12950507 0.17 ENSDART00000067629
ENSDART00000158004
saa
serum amyloid A
chr18_+_30567945 0.16 ENSDART00000078894
irf8
interferon regulatory factor 8
chr13_-_5257303 0.16 ENSDART00000110610
si:dkey-78p8.1
si:dkey-78p8.1
chr11_-_25734417 0.16 ENSDART00000103570
brpf3a
bromodomain and PHD finger containing, 3a
chr23_+_29966466 0.15 ENSDART00000143583
dvl1a
dishevelled segment polarity protein 1a
chr20_-_28433616 0.15 ENSDART00000169289
wdr21
WD repeat domain 21
chr13_-_9300299 0.15 ENSDART00000144142
HTRA2 (1 of many)
si:dkey-33c12.12
chr24_-_26820698 0.15 ENSDART00000147788
fndc3bb
fibronectin type III domain containing 3Bb
chr13_-_36049008 0.15 ENSDART00000189978
lgmn
legumain
chr6_+_30689239 0.14 ENSDART00000065206
wdr78
WD repeat domain 78
chr2_-_27330181 0.14 ENSDART00000137053
tmx3a
thioredoxin related transmembrane protein 3a
chr20_+_46513651 0.14 ENSDART00000152977
zc3h14
zinc finger CCCH-type containing 14
chr5_-_42071505 0.14 ENSDART00000137224
ENSDART00000193721
cxcl11.7
cenpv
chemokine (C-X-C motif) ligand 11, duplicate 7
centromere protein V
chr22_-_9896180 0.14 ENSDART00000138343
znf990
zinc finger protein 990
chr19_+_9033376 0.14 ENSDART00000192298
ENSDART00000052915
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr22_-_28645676 0.14 ENSDART00000005883
jagn1b
jagunal homolog 1b
chr3_-_41292569 0.13 ENSDART00000111856
sdk1a
sidekick cell adhesion molecule 1a
chr14_-_52433292 0.13 ENSDART00000164272
rest
RE1-silencing transcription factor
chr10_-_28519309 0.13 ENSDART00000142476
bbx
bobby sox homolog (Drosophila)
chr7_-_29043075 0.13 ENSDART00000052342
thap11
THAP domain containing 11
chr1_-_28831848 0.12 ENSDART00000148536
GK3P
zgc:172295
chr3_+_22327738 0.12 ENSDART00000055675
gh1
growth hormone 1
chr7_-_34434889 0.12 ENSDART00000159982
nr1h3
nuclear receptor subfamily 1, group H, member 3
chr11_+_8152872 0.12 ENSDART00000091638
ENSDART00000138057
ENSDART00000166379
samd13
sterile alpha motif domain containing 13
chr6_+_39923052 0.12 ENSDART00000149019
itpr1a
inositol 1,4,5-trisphosphate receptor, type 1a
chr23_-_17451264 0.12 ENSDART00000190748
tpd52l2b
tumor protein D52-like 2b
chr15_-_5222597 0.12 ENSDART00000123819
or128-4
odorant receptor, family E, subfamily 128, member 4
chr3_-_33901483 0.11 ENSDART00000144774
ENSDART00000138765
cacna1aa
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a
chr11_+_19603251 0.11 ENSDART00000005639
thoc7
THO complex 7
chr23_-_3802071 0.10 ENSDART00000183839
opn7b
opsin 7, group member b
chr18_+_49411417 0.10 ENSDART00000028944
LRFN3
zmp:0000001073
chr20_+_27427112 0.10 ENSDART00000153459
si:dkey-22l1.1
si:dkey-22l1.1
chr20_+_6493648 0.10 ENSDART00000099846
mep1b
meprin A, beta
chr17_+_45454943 0.10 ENSDART00000074838
kcnk3b
potassium channel, subfamily K, member 3b
chr6_-_22369125 0.10 ENSDART00000083038
nprl2
NPR2 like, GATOR1 complex subunit
chr24_+_24923166 0.10 ENSDART00000065288
pcyt1ba
phosphate cytidylyltransferase 1, choline, beta a
chr22_-_29906764 0.09 ENSDART00000019786
smc3
structural maintenance of chromosomes 3
chr5_-_58780160 0.09 ENSDART00000166955
arhgef12b
Rho guanine nucleotide exchange factor (GEF) 12b
chr6_+_52947186 0.09 ENSDART00000155831
uba7
ubiquitin-like modifier activating enzyme 7
chr22_+_1462177 0.09 ENSDART00000164685
si:dkeyp-53d3.5
si:dkeyp-53d3.5
chr21_-_22485847 0.09 ENSDART00000162860
myo5b
myosin VB

Network of associatons between targets according to the STRING database.

First level regulatory network of stat4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 0.8 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.3 1.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 0.8 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 0.6 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.2 0.8 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.5 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.1 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.7 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.4 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 0.7 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.5 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.1 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.3 GO:0016038 absorption of visible light(GO:0016038)
0.1 0.3 GO:0042706 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 0.4 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.2 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.7 GO:0030719 P granule organization(GO:0030719)
0.1 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.2 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.7 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.3 GO:0044783 G1 DNA damage checkpoint(GO:0044783)
0.0 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.3 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.1 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.2 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 0.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785) negative regulation of cell maturation(GO:1903430)
0.0 0.1 GO:1904729 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.2 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 1.2 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.1 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.5 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.6 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.0 0.1 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.4 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.2 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.9 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.8 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 0.4 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.3 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.2 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.2 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.0 GO:0002857 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.4 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.6 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.4 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.4 GO:0072114 pronephros morphogenesis(GO:0072114)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990745 EARP complex(GO:1990745)
0.1 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.6 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0097541 axonemal basal plate(GO:0097541)
0.0 0.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 1.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.3 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.6 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.6 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 0.4 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.7 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.3 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.4 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.7 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.2 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.0 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.0 1.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.7 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 1.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 SIG CHEMOTAXIS Genes related to chemotaxis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK