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PRJNA195909:zebrafish embryo and larva development

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Results for tbp

Z-value: 6.88

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Transcription factors associated with tbp

Gene Symbol Gene ID Gene Info
tbp
ENSDARG00000014994 TATA box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbpdr11_v1_chr13_-_24396003_24396003-0.932.9e-04Click!

Activity profile of tbp motif

Sorted Z-values of tbp motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22240052 24.81 ENSDART00000111109
crygm2d9
crystallin, gamma M2d9
chr9_-_22232902 24.34 ENSDART00000101845
crygm2d5
crystallin, gamma M2d5
chr3_-_32818607 20.16 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr9_-_22245572 19.25 ENSDART00000114943
crygm2d4
crystallin, gamma M2d4
chr9_-_22158784 19.12 ENSDART00000167850
crygm2d14
crystallin, gamma M2d14
chr9_-_22299412 18.76 ENSDART00000139101
crygm2d21
crystallin, gamma M2d21
chr9_-_22281854 18.07 ENSDART00000146319
crygm2d3
crystallin, gamma M2d3
chr9_-_22213297 18.00 ENSDART00000110656
ENSDART00000133149
crygm2d20
crystallin, gamma M2d20
chr9_-_22135576 17.12 ENSDART00000101902
crygm2d8
crystallin, gamma M2d8
chr12_-_17712393 16.44 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr5_+_37978501 16.40 ENSDART00000012050
apoa1a
apolipoprotein A-Ia
chr5_-_32274383 15.49 ENSDART00000122889
myhz1.3
myosin, heavy polypeptide 1.3, skeletal muscle
chr9_-_22135420 15.03 ENSDART00000184959
crygm2d8
crystallin, gamma M2d8
chr3_-_55121125 14.87 ENSDART00000125092
hbae1
hemoglobin, alpha embryonic 1
chr19_-_5345930 14.81 ENSDART00000066620
ENSDART00000151398
krtt1c19e
keratin type 1 c19e
chr9_-_22129788 14.55 ENSDART00000124272
ENSDART00000175417
crygm2d8
crystallin, gamma M2d8
chr9_-_22117430 14.35 ENSDART00000101916
crygm2d15
crystallin, gamma M2d15
chr24_-_41312459 14.21 ENSDART00000041349
crygn2
crystallin, gamma N2
chr9_-_22318511 14.17 ENSDART00000129295
crygm2d2
crystallin, gamma M2d2
chr2_+_16780643 13.89 ENSDART00000125647
ENSDART00000108611
ENSDART00000181245
ENSDART00000163194
tfa
transferrin-a
chr9_-_22272181 13.69 ENSDART00000113174
crygm2d7
crystallin, gamma M2d7
chr10_-_44027391 13.39 ENSDART00000145404
crybb1
crystallin, beta B1
chr16_-_45917322 13.17 ENSDART00000060822
afp4
antifreeze protein type IV
chr9_-_22182396 12.98 ENSDART00000101809
crygm2d6
crystallin, gamma M2d6
chr18_-_46010 12.73 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr2_+_16781015 12.49 ENSDART00000155147
ENSDART00000003845
tfa
transferrin-a
chr9_-_22158325 12.27 ENSDART00000114568
crygm2d16
crystallin, gamma M2d16
chr5_-_36837846 12.26 ENSDART00000032481
ckma
creatine kinase, muscle a
chr5_-_71722257 12.18 ENSDART00000013404
ak1
adenylate kinase 1
chr5_-_30615901 12.18 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr8_+_6863462 11.15 ENSDART00000064163
nefmb
neurofilament, medium polypeptide b
chr9_-_22188117 11.08 ENSDART00000132890
crygm2d17
crystallin, gamma M2d17
chr8_+_999421 10.72 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr5_+_4366431 10.38 ENSDART00000168560
ENSDART00000149185
sat1a.2
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr9_-_22339582 10.19 ENSDART00000134805
crygm2d1
crystallin, gamma M2d1
chr8_+_26818446 10.06 ENSDART00000134987
ENSDART00000138835
si:ch211-156j16.1
si:ch211-156j16.1
chr16_-_45917683 10.03 ENSDART00000184289
afp4
antifreeze protein type IV
chr3_-_31804481 10.00 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr7_+_29951997 9.99 ENSDART00000173453
tpma
alpha-tropomyosin
chr24_+_32176155 9.33 ENSDART00000003745
vim
vimentin
chr20_-_9980318 9.27 ENSDART00000080664
ACTC1
zgc:86709
chr9_-_22147567 8.63 ENSDART00000110941
crygm2d14
crystallin, gamma M2d14
chr3_+_15505275 8.40 ENSDART00000141714
nupr1
nuclear protein 1
chr9_+_22080122 8.39 ENSDART00000065956
ENSDART00000136014
crygm2e
crystallin, gamma M2e
chr8_+_48613040 8.32 ENSDART00000121432
nppa
natriuretic peptide A
chr5_-_25583125 8.27 ENSDART00000031665
ENSDART00000145353
anxa1a
annexin A1a
chr24_+_3307857 8.14 ENSDART00000106527
gyg1b
glycogenin 1b
chr9_-_45602978 8.04 ENSDART00000139019
ENSDART00000085763
agr1
anterior gradient 1
chr23_-_21446985 8.02 ENSDART00000044080
her12
hairy-related 12
chr12_-_35988586 7.88 ENSDART00000157746
pde6gb
phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b
chr6_+_35362225 7.63 ENSDART00000133783
ENSDART00000102483
rgs4
regulator of G protein signaling 4
chr5_-_67911111 7.61 ENSDART00000051833
gsx1
GS homeobox 1
chr21_+_20383837 7.60 ENSDART00000026430
hspb11
heat shock protein, alpha-crystallin-related, b11
chr15_-_5815006 7.54 ENSDART00000102459
rbp2a
retinol binding protein 2a, cellular
chr8_+_17078692 7.40 ENSDART00000023206
plk2b
polo-like kinase 2b (Drosophila)
chr19_+_10845953 7.34 ENSDART00000157589
apoa4a
apolipoprotein A-IV a
chr24_-_25691020 7.31 ENSDART00000015391
chrnd
cholinergic receptor, nicotinic, delta (muscle)
chr23_+_27675581 7.30 ENSDART00000127198
rps26
ribosomal protein S26
chr11_+_34235372 7.28 ENSDART00000063150
fam43a
family with sequence similarity 43, member A
chr2_-_38000276 7.21 ENSDART00000034790
pcp4l1
Purkinje cell protein 4 like 1
chr6_+_269204 7.17 ENSDART00000191678
atf4a
activating transcription factor 4a
chr5_+_37837245 6.95 ENSDART00000171617
epd
ependymin
chr5_-_64168415 6.86 ENSDART00000048395
cmlc1
cardiac myosin light chain-1
chr16_+_23960744 6.82 ENSDART00000058965
apoeb
apolipoprotein Eb
chr1_+_29096881 6.65 ENSDART00000075539
cryaa
crystallin, alpha A
chr21_+_7823146 6.61 ENSDART00000030579
crhbp
corticotropin releasing hormone binding protein
chr9_+_23900703 6.60 ENSDART00000127859
trim63b
tripartite motif containing 63b
chr16_+_23960933 6.58 ENSDART00000146077
apoeb
apolipoprotein Eb
chr19_-_5332784 6.45 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr19_-_41069573 6.18 ENSDART00000111982
ENSDART00000193142
sgce
sarcoglycan, epsilon
chr23_-_10177442 6.14 ENSDART00000144280
ENSDART00000129044
krt5
keratin 5
chr5_-_27867657 6.04 ENSDART00000112495
tcima
transcriptional and immune response regulator a
chr7_-_31441420 6.02 ENSDART00000075398
cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr19_+_24882845 5.97 ENSDART00000010580
si:ch211-195b13.1
si:ch211-195b13.1
chr3_+_33340939 5.94 ENSDART00000128786
pyya
peptide YYa
chr23_+_45456490 5.92 ENSDART00000036631
cyr61
cysteine-rich, angiogenic inducer, 61
chr10_-_24371312 5.91 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr5_+_9348284 5.88 ENSDART00000149417
tal2
T-cell acute lymphocytic leukemia 2
chr22_-_24248420 5.87 ENSDART00000165433
rgs2
regulator of G protein signaling 2
chr2_+_24536762 5.84 ENSDART00000144149
angptl4
angiopoietin-like 4
chr7_+_20524064 5.80 ENSDART00000052917
slc3a2a
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr22_-_11626014 5.55 ENSDART00000063133
ENSDART00000160085
gcga
glucagon a
chr2_-_30182353 5.54 ENSDART00000019149
rpl7
ribosomal protein L7
chr8_+_48609521 5.27 ENSDART00000060765
nppb
natriuretic peptide B
chr1_+_55137943 5.23 ENSDART00000138070
ENSDART00000150510
ENSDART00000133472
ENSDART00000136378
mb
myoglobin
chr10_-_7785930 5.21 ENSDART00000043961
ENSDART00000111058
mpx
myeloid-specific peroxidase
chr6_+_41181869 5.16 ENSDART00000002046
opn1mw1
opsin 1 (cone pigments), medium-wave-sensitive, 1
chr15_+_28368823 5.08 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr6_-_54180699 4.93 ENSDART00000045901
rps10
ribosomal protein S10
chr4_+_25706037 4.90 ENSDART00000141133
lamb1b
laminin, beta 1b
chr14_+_45406299 4.89 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr3_-_36606884 4.76 ENSDART00000172003
si:dkeyp-72e1.6
si:dkeyp-72e1.6
chr2_+_24507597 4.65 ENSDART00000133109
rps28
ribosomal protein S28
chr22_+_5752257 4.64 ENSDART00000143052
cox14
COX14 cytochrome c oxidase assembly factor
chr18_-_26854959 4.59 ENSDART00000057553
ch25hl1.1
cholesterol 25-hydroxylase like 1, tandem duplicate 1
chr2_-_1443692 4.58 ENSDART00000004533
rpe65a
retinal pigment epithelium-specific protein 65a
chr21_-_20341836 4.55 ENSDART00000176689
rbp4l
retinol binding protein 4, like
chr25_+_8356707 4.55 ENSDART00000153708
muc5.1
mucin 5.1, oligomeric mucus/gel-forming
chr6_-_53426773 4.53 ENSDART00000162791
mst1
macrophage stimulating 1
chr9_-_1703761 4.43 ENSDART00000144822
ENSDART00000137210
ENSDART00000135273
hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
chr14_-_11430566 4.42 ENSDART00000137154
ENSDART00000091158
irg1l
immunoresponsive gene 1, like
chr1_+_10683843 4.38 ENSDART00000054879
zgc:103678
zgc:103678
chr20_+_27020201 4.35 ENSDART00000126919
ENSDART00000016014
chga
chromogranin A
chr2_+_55365727 4.34 ENSDART00000162943
FP245456.1

chr23_+_19813677 4.34 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr24_+_21621654 4.30 ENSDART00000002595
rpl21
ribosomal protein L21
chr1_-_22678471 4.15 ENSDART00000128918
fgfbp1b
fibroblast growth factor binding protein 1b
chr14_-_28001986 4.12 ENSDART00000054115
tsc22d3
TSC22 domain family, member 3
chr13_+_25455319 4.12 ENSDART00000145948
pkd2l1
polycystic kidney disease 2-like 1
chr2_+_24507770 4.11 ENSDART00000154802
ENSDART00000052063
rps28
ribosomal protein S28
chr21_-_28523548 4.11 ENSDART00000077910
epdl2
ependymin-like 2
chr17_-_37214196 3.93 ENSDART00000128715
kif3cb
kinesin family member 3Cb
chr12_+_39034541 3.90 ENSDART00000182502
ENSDART00000169813
si:dkey-239b22.2
si:dkey-239b22.2
chr15_+_19682013 3.86 ENSDART00000127368
si:dkey-4p15.5
si:dkey-4p15.5
chr6_-_346084 3.82 ENSDART00000162599
pde6ha
phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a
chr11_+_3575963 3.76 ENSDART00000077305
si:dkey-33m11.8
si:dkey-33m11.8
chr23_+_25305431 3.74 ENSDART00000143291
RPL41
si:dkey-151g10.6
chr20_-_22464250 3.73 ENSDART00000165904
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr7_+_57795974 3.70 ENSDART00000148369
camk2d1
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr11_+_25477643 3.62 ENSDART00000065941
opn1lw1
opsin 1 (cone pigments), long-wave-sensitive, 1
chr22_+_16497670 3.61 ENSDART00000014330
ier5
immediate early response 5
chr13_+_35745572 3.59 ENSDART00000159690
gpr75
G protein-coupled receptor 75
chr21_-_20342096 3.59 ENSDART00000065659
rbp4l
retinol binding protein 4, like
chr23_+_18103080 3.56 ENSDART00000010270
mfsd4ab
major facilitator superfamily domain containing 4Ab
chr11_+_15613218 3.54 ENSDART00000066033
gdf11
growth differentiation factor 11
chr11_-_6970107 3.52 ENSDART00000171255
COMP
si:ch211-43f4.1
chr19_+_19976990 3.51 ENSDART00000052627
npvf
neuropeptide VF precursor
chr19_-_3167729 3.50 ENSDART00000110763
ENSDART00000145710
ENSDART00000074620
ENSDART00000105174
stm
starmaker
chr8_-_22965214 3.46 ENSDART00000148178
emilin3a
elastin microfibril interfacer 3a
chr6_+_39499623 3.44 ENSDART00000036057
si:ch211-173n18.3
si:ch211-173n18.3
chr4_+_842010 3.41 ENSDART00000067461
si:ch211-152c2.3
si:ch211-152c2.3
chr12_-_29624638 3.40 ENSDART00000126744
nrg3b
neuregulin 3b
chr22_-_21392748 3.37 ENSDART00000144648
ankrd24
ankyrin repeat domain 24
chr7_-_35083184 3.37 ENSDART00000100253
ENSDART00000135250
ENSDART00000173511
agrp
agouti related neuropeptide
chr10_+_15777258 3.33 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr10_+_38593645 3.30 ENSDART00000011573
mmp13a
matrix metallopeptidase 13a
chr10_-_6775271 3.28 ENSDART00000110735
zgc:194281
zgc:194281
chr11_-_3334248 3.27 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr1_+_56447107 3.23 ENSDART00000091924
CABZ01059392.1

chr7_+_8456999 3.20 ENSDART00000172880
jac4
jacalin 4
chr19_-_42557416 3.17 ENSDART00000163217
ENSDART00000128278
ENSDART00000162304
ENSDART00000166556
si:dkey-267n13.1
si:dkey-267n13.1
chr25_-_34632050 3.15 ENSDART00000170671
megf8
multiple EGF-like-domains 8
chr9_-_32753535 3.06 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr15_+_45643787 3.02 ENSDART00000055995
ENSDART00000157750
sagb
S-antigen; retina and pineal gland (arrestin) b
chr19_-_3193912 3.01 ENSDART00000133159
si:ch211-133n4.6
si:ch211-133n4.6
chr12_+_48204891 3.01 ENSDART00000190534
ENSDART00000164427
ndr2
nodal-related 2
chr13_+_23176330 3.01 ENSDART00000168351
sorbs1
sorbin and SH3 domain containing 1
chr18_+_30507839 2.98 ENSDART00000026866
cox4i1
cytochrome c oxidase subunit IV isoform 1
chr23_+_26979174 2.95 ENSDART00000018654
rnd1b
Rho family GTPase 1b
chr7_-_35083585 2.95 ENSDART00000192732
agrp
agouti related neuropeptide
chr12_-_19346678 2.93 ENSDART00000044860
maff
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr10_-_44924289 2.92 ENSDART00000171267
tuba7l
tubulin, alpha 7 like
chr25_+_30298377 2.92 ENSDART00000153622
C11orf96
chromosome 11 open reading frame 96
chr11_-_27702778 2.90 ENSDART00000045942
ENSDART00000125352
phf2
PHD finger protein 2
chr1_-_22338521 2.89 ENSDART00000176849
si:ch73-380n15.2
si:ch73-380n15.2
chr23_+_43950674 2.88 ENSDART00000167813
corin
corin, serine peptidase
chr11_-_39202915 2.88 ENSDART00000105133
wnt4a
wingless-type MMTV integration site family, member 4a
chr14_-_33334065 2.87 ENSDART00000052761
rpl39
ribosomal protein L39
chr3_+_59051503 2.83 ENSDART00000160767
rasd4
rasd family member 4
chr16_-_7228276 2.82 ENSDART00000149030
nt5c3a
5'-nucleotidase, cytosolic IIIA
chr5_-_33259079 2.81 ENSDART00000132223
ifitm1
interferon induced transmembrane protein 1
chr21_+_43669943 2.79 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr13_-_20381485 2.77 ENSDART00000131351
si:ch211-270n8.1
si:ch211-270n8.1
chr10_-_5058823 2.72 ENSDART00000139825
tmem150c
transmembrane protein 150C
chr13_-_2215213 2.71 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr20_-_53981626 2.68 ENSDART00000023550
hsp90aa1.2
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr3_-_60401826 2.67 ENSDART00000144030
ENSDART00000160821
si:ch211-214b16.4
si:ch211-214b16.4
chr8_-_6877390 2.65 ENSDART00000170883
ENSDART00000005321
neflb
neurofilament, light polypeptide b
chr10_+_17776981 2.64 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr20_+_42668875 2.62 ENSDART00000048890
slc22a2
solute carrier family 22 (organic cation transporter), member 2
chr10_-_22845485 2.60 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr10_+_42374957 2.59 ENSDART00000147926
COX5B
zgc:86599
chr4_+_75314247 2.58 ENSDART00000162365
CABZ01041913.1

chr20_-_33976937 2.58 ENSDART00000136834
sele
selectin E
chr10_-_37075361 2.55 ENSDART00000132023
myo18aa
myosin XVIIIAa
chr3_+_5575313 2.55 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
si:ch211-106h11.3
chr10_-_43964028 2.51 ENSDART00000009134
ENSDART00000133450
sept5b
septin 5b
chr2_+_43920461 2.47 ENSDART00000123673
si:ch211-195h23.3
si:ch211-195h23.3
chr16_-_44349845 2.43 ENSDART00000170932
rims2a
regulating synaptic membrane exocytosis 2a
chr3_-_57425961 2.39 ENSDART00000033716
socs3a
suppressor of cytokine signaling 3a
chr22_-_20515347 2.38 ENSDART00000137371
atp8b3
ATPase phospholipid transporting 8B3
chr13_-_12645584 2.36 ENSDART00000176216
adh8b
alcohol dehydrogenase 8b
chr11_+_42478184 2.34 ENSDART00000089963
zgc:110286
zgc:110286
chr10_+_17026870 2.33 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr6_+_39493864 2.33 ENSDART00000086263
mettl7a
methyltransferase like 7A
chr23_-_18913032 2.32 ENSDART00000136678
si:ch211-209j10.6
si:ch211-209j10.6
chr19_+_41769135 2.32 ENSDART00000087096
tinagl1
tubulointerstitial nephritis antigen-like 1
chr16_+_20161805 2.31 ENSDART00000192146
c16h2orf66
chromosome 16 C2orf66 homolog
chr9_+_22017368 2.28 ENSDART00000023059
zgc:153846
zgc:153846
chr20_-_39273987 2.26 ENSDART00000127173
clu
clusterin
chr2_-_7431590 2.24 ENSDART00000185699
asip2b
agouti signaling protein, nonagouti homolog (mouse) 2b
chr24_-_37688398 2.22 ENSDART00000141414
zgc:112185
zgc:112185
chr13_-_15702672 2.20 ENSDART00000144445
ENSDART00000168950
ckba
creatine kinase, brain a
chr24_-_5786759 2.18 ENSDART00000152069
chst2b
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2b
chr11_+_6456146 2.17 ENSDART00000036939
gadd45ba
growth arrest and DNA-damage-inducible, beta a
chr15_+_1134870 2.17 ENSDART00000155392
p2ry13
purinergic receptor P2Y13
chr13_+_35746440 2.15 ENSDART00000187859
gpr75
G protein-coupled receptor 75
chr6_-_49173891 2.14 ENSDART00000132867
ngfb
nerve growth factor b (beta polypeptide)
chr3_-_58733718 2.13 ENSDART00000154603
si:ch73-281f12.4
si:ch73-281f12.4
chr22_-_9934854 2.12 ENSDART00000136404
si:dkey-253d23.11
si:dkey-253d23.11

Network of associatons between targets according to the STRING database.

First level regulatory network of tbp

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.6 GO:1905072 cardiac jelly development(GO:1905072)
4.5 13.4 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
4.2 12.7 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
3.7 11.0 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
3.3 16.4 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
2.6 10.4 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
2.4 317.2 GO:0002088 lens development in camera-type eye(GO:0002088)
2.4 26.4 GO:0019731 antibacterial humoral response(GO:0019731)
1.9 11.7 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
1.9 5.7 GO:0060986 regulation of endocrine process(GO:0044060) endocrine hormone secretion(GO:0060986)
1.9 11.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
1.7 12.2 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
1.5 5.9 GO:0090299 regulation of neural crest formation(GO:0090299)
1.4 8.3 GO:0002825 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.1 4.6 GO:0016122 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
1.1 6.9 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
1.1 14.5 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.0 4.1 GO:0007638 mechanosensory behavior(GO:0007638)
1.0 2.9 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.9 6.3 GO:2000253 adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253)
0.9 2.6 GO:0015695 organic cation transport(GO:0015695)
0.8 2.4 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.8 3.1 GO:0021742 abducens nucleus development(GO:0021742)
0.7 3.7 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.7 5.8 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.7 23.2 GO:0060030 dorsal convergence(GO:0060030)
0.6 1.9 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.6 1.9 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.6 13.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.6 4.4 GO:0090594 inflammatory response to wounding(GO:0090594)
0.5 2.7 GO:0046677 response to antibiotic(GO:0046677)
0.5 3.5 GO:0045299 otolith mineralization(GO:0045299)
0.5 1.8 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.5 3.6 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.4 4.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 2.9 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.4 5.2 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.4 2.8 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.4 1.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 5.9 GO:0007631 feeding behavior(GO:0007631)
0.3 1.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.3 2.4 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.3 0.3 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.3 1.9 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.3 1.4 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.3 1.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 5.2 GO:0014823 response to activity(GO:0014823)
0.3 1.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.3 4.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3 3.0 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.2 1.0 GO:0035994 response to muscle stretch(GO:0035994)
0.2 1.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 11.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 3.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.4 GO:0016559 peroxisome fission(GO:0016559)
0.2 4.0 GO:0031033 myosin filament organization(GO:0031033)
0.2 0.8 GO:0007620 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) positive regulation of amine transport(GO:0051954) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.2 1.0 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.2 1.4 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.2 5.6 GO:0003323 type B pancreatic cell development(GO:0003323)
0.2 1.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 1.6 GO:0006465 signal peptide processing(GO:0006465)
0.2 5.9 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.2 2.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 6.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 2.5 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.2 4.9 GO:0070831 basement membrane assembly(GO:0070831)
0.2 0.9 GO:0016322 neuron remodeling(GO:0016322)
0.2 2.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 1.9 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.2 0.9 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 17.4 GO:0031101 fin regeneration(GO:0031101)
0.2 2.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 1.4 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 3.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.2 1.4 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 2.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 3.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 0.7 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 4.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 5.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 2.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 2.6 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 1.3 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 0.7 GO:0032218 riboflavin transport(GO:0032218)
0.1 4.9 GO:1901214 regulation of neuron death(GO:1901214)
0.1 1.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 2.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.9 GO:0071219 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.1 5.2 GO:0015914 phospholipid transport(GO:0015914)
0.1 4.5 GO:0030282 bone mineralization(GO:0030282)
0.1 1.6 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 1.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 3.3 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 4.4 GO:0031018 endocrine pancreas development(GO:0031018)
0.1 6.5 GO:0061515 myeloid cell development(GO:0061515)
0.1 7.3 GO:0030239 myofibril assembly(GO:0030239)
0.1 3.5 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.1 2.1 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.1 7.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 5.1 GO:0097530 granulocyte migration(GO:0097530)
0.1 7.3 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.1 3.9 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 4.5 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 1.9 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 2.5 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 2.7 GO:0010506 regulation of autophagy(GO:0010506)
0.0 3.7 GO:0042060 wound healing(GO:0042060)
0.0 4.1 GO:0033993 response to lipid(GO:0033993)
0.0 1.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0046661 male sex differentiation(GO:0046661)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 0.4 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 2.5 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 8.8 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.0 4.8 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 8.1 GO:0006412 translation(GO:0006412)
0.0 0.7 GO:0051607 defense response to virus(GO:0051607)
0.0 0.6 GO:0002028 regulation of sodium ion transport(GO:0002028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
2.9 8.8 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
2.8 13.8 GO:0005883 neurofilament(GO:0005883)
1.7 11.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
1.4 16.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.9 6.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.9 10.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.7 6.6 GO:0042583 chromaffin granule(GO:0042583)
0.6 6.1 GO:0045095 keratin filament(GO:0045095)
0.6 7.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.6 8.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.4 40.3 GO:0005882 intermediate filament(GO:0005882)
0.4 1.6 GO:0005787 signal peptidase complex(GO:0005787)
0.4 1.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.4 14.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.3 12.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 4.9 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 12.7 GO:0022626 cytosolic ribosome(GO:0022626)
0.2 18.3 GO:0055037 recycling endosome(GO:0055037)
0.2 2.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 1.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 1.1 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 2.7 GO:0043209 myelin sheath(GO:0043209)
0.1 18.6 GO:0016459 myosin complex(GO:0016459)
0.1 0.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 4.7 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.8 GO:0030008 TRAPP complex(GO:0030008)
0.1 2.5 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 2.4 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.1 9.6 GO:0005884 actin filament(GO:0005884)
0.1 2.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.7 GO:0016605 PML body(GO:0016605)
0.1 15.6 GO:0005764 lysosome(GO:0005764)
0.0 58.5 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 13.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 3.7 GO:0005871 kinesin complex(GO:0005871)
0.0 26.8 GO:0005576 extracellular region(GO:0005576)
0.0 4.6 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 3.3 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 1.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.5 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
3.9 313.6 GO:0005212 structural constituent of eye lens(GO:0005212)
3.3 16.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.7 8.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
1.5 10.4 GO:0019809 spermidine binding(GO:0019809)
1.4 8.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.2 5.9 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
1.2 8.1 GO:0034632 retinol transporter activity(GO:0034632)
1.1 4.6 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
1.1 14.5 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.0 7.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
1.0 2.9 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.9 12.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.9 3.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.9 11.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.8 5.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.7 10.7 GO:0005504 fatty acid binding(GO:0005504)
0.7 4.9 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.7 2.7 GO:0005521 lamin binding(GO:0005521)
0.6 2.3 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.5 2.6 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.5 1.9 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.4 1.8 GO:0070513 death domain binding(GO:0070513)
0.4 1.3 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.4 3.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.4 2.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 12.7 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.4 1.9 GO:0031769 glucagon receptor binding(GO:0031769)
0.3 7.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 0.9 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 5.2 GO:0019825 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.2 4.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 2.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 6.0 GO:0005112 Notch binding(GO:0005112)
0.2 11.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 2.6 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.2 1.3 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.2 0.9 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.2 3.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 3.6 GO:0015149 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.2 1.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 14.4 GO:0051427 hormone receptor binding(GO:0051427)
0.2 0.7 GO:0004064 arylesterase activity(GO:0004064)
0.2 2.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 6.6 GO:0017046 peptide hormone binding(GO:0017046)
0.2 6.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 33.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 1.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 2.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 2.1 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 1.9 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.9 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 3.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 2.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 7.4 GO:0005178 integrin binding(GO:0005178)
0.1 1.4 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 51.4 GO:0005198 structural molecule activity(GO:0005198)
0.1 0.7 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 5.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 5.2 GO:0004601 peroxidase activity(GO:0004601)
0.1 1.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 22.3 GO:0003774 motor activity(GO:0003774)
0.1 3.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.3 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.1 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.4 GO:0008301 DNA binding, bending(GO:0008301)
0.1 3.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 2.8 GO:0019003 GDP binding(GO:0019003)
0.1 2.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 3.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 2.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 2.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.8 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 2.1 GO:0051020 GTPase binding(GO:0051020)
0.1 59.8 GO:0005509 calcium ion binding(GO:0005509)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 4.8 GO:0019838 growth factor binding(GO:0019838)
0.0 2.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.9 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 2.4 GO:0044325 ion channel binding(GO:0044325)
0.0 10.5 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 6.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.3 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 2.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0042805 actinin binding(GO:0042805) muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 8.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.0 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 1.5 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 2.1 GO:0060090 binding, bridging(GO:0060090)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 2.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.0 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4 6.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 9.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 6.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 8.1 PID AP1 PATHWAY AP-1 transcription factor network
0.1 6.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.5 PID FOXO PATHWAY FoxO family signaling
0.1 11.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.0 9.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.8 7.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.6 12.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 8.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4 21.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 2.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 10.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 16.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 2.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 7.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 2.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 2.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 0.9 REACTOME OPSINS Genes involved in Opsins
0.1 1.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 6.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 5.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 6.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 4.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 2.2 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.8 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling