Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for tbx15_tbx1_mgaa_tbx4

Z-value: 1.66

Motif logo

logo of logo of logo of logo of

Transcription factors associated with tbx15_tbx1_mgaa_tbx4

Gene Symbol Gene ID Gene Info
tbx15
ENSDARG00000002582 T-box transcription factor 15
tbx1
ENSDARG00000031891 T-box transcription factor 1
mgaa
ENSDARG00000078784 MAX dimerization protein MGA a
tbx4
ENSDARG00000030058 T-box transcription factor 4
tbx4
ENSDARG00000113067 T-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbx1dr11_v1_chr5_+_15202495_152024950.571.1e-01Click!
mgaadr11_v1_chr17_+_10566490_10566495-0.481.9e-01Click!
tbx15dr11_v1_chr9_-_21067673_210676730.373.3e-01Click!
tbx4dr11_v1_chr15_+_27384798_273847980.107.9e-01Click!

Activity profile of tbx15_tbx1_mgaa_tbx4 motif

Sorted Z-values of tbx15_tbx1_mgaa_tbx4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_26965351 3.52 ENSDART00000114215
ENSDART00000147192
grhl3
grainyhead-like transcription factor 3
chr17_-_42568498 3.35 ENSDART00000014296
foxa2
forkhead box A2
chr23_+_23232136 3.34 ENSDART00000126479
ENSDART00000187764
plekhn1
pleckstrin homology domain containing, family N member 1
chr11_-_11575070 3.31 ENSDART00000142208
zgc:110712
zgc:110712
chr7_-_58776400 2.87 ENSDART00000167433
sox17
SRY (sex determining region Y)-box 17
chr25_-_11016675 2.79 ENSDART00000099572
mespab
mesoderm posterior ab
chr15_-_1590858 2.59 ENSDART00000081875
nnr
nanor
chr1_-_12126535 2.57 ENSDART00000164817
ENSDART00000015251
mttp
microsomal triglyceride transfer protein
chr6_+_56141852 2.55 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr13_+_14976108 2.35 ENSDART00000011520
noto
notochord homeobox
chr14_-_5817039 2.09 ENSDART00000131820
kazald2
Kazal-type serine peptidase inhibitor domain 2
chr7_-_58826164 2.06 ENSDART00000171095
sox32
SRY (sex determining region Y)-box 32
chr21_+_13301798 2.06 ENSDART00000140206
adora2ab
adenosine A2a receptor b
chr19_-_7420867 2.01 ENSDART00000081741
rab25a
RAB25, member RAS oncogene family a
chr8_-_4508248 1.93 ENSDART00000141915
si:ch211-166a6.5
si:ch211-166a6.5
chr19_+_14059349 1.86 ENSDART00000166230
tpbga
trophoblast glycoprotein a
chr11_+_25257022 1.79 ENSDART00000156052
tp53inp2
tumor protein p53 inducible nuclear protein 2
chr13_+_18533005 1.71 ENSDART00000136024
ftr14l
finTRIM family, member 14-like
chr5_+_27525477 1.69 ENSDART00000051491
sfrp1a
secreted frizzled-related protein 1a
chr17_-_8312923 1.68 ENSDART00000064678
lft2
lefty2
chr9_+_15837398 1.66 ENSDART00000141063
si:dkey-103d23.5
si:dkey-103d23.5
chr8_-_24252933 1.56 ENSDART00000057624
zgc:110353
zgc:110353
chr14_+_45406299 1.55 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr21_+_30351256 1.54 ENSDART00000078341
foxi3a
forkhead box I3a
chr3_-_53533128 1.53 ENSDART00000183591
notch3
notch 3
chr7_+_15329819 1.50 ENSDART00000006018
mespaa
mesoderm posterior aa
chr23_-_39849155 1.48 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr2_-_53500424 1.44 ENSDART00000037557
admp
anti-dorsalizing morphogenic protein
chr9_-_21970067 1.43 ENSDART00000009920
lmo7a
LIM domain 7a
chr3_-_23643751 1.36 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr11_+_24729346 1.34 ENSDART00000087740
zgc:153953
zgc:153953
chr7_+_6969909 1.32 ENSDART00000189886
actn3b
actinin alpha 3b
chr4_+_912563 1.32 ENSDART00000103631
ripply2
ripply transcriptional repressor 2
chr7_+_7048245 1.29 ENSDART00000001649
actn3b
actinin alpha 3b
chr19_-_5372572 1.26 ENSDART00000151326
krt17
keratin 17
chr13_+_22295905 1.26 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr1_-_52498146 1.24 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr16_-_26676685 1.21 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr13_-_33822550 1.18 ENSDART00000143703
flrt3
fibronectin leucine rich transmembrane 3
chr19_-_9776075 1.17 ENSDART00000140332
si:dkey-14o18.1
si:dkey-14o18.1
chr22_-_12160283 1.16 ENSDART00000146785
ENSDART00000128176
tmem163b
transmembrane protein 163b
chr7_-_34262080 1.15 ENSDART00000183246
si:ch211-98n17.5
si:ch211-98n17.5
chr7_-_52417777 1.14 ENSDART00000110265
myzap
myocardial zonula adherens protein
chr16_+_53203370 1.12 ENSDART00000154669
si:ch211-269k10.2
si:ch211-269k10.2
chr8_-_11229523 1.11 ENSDART00000002164
unc45b
unc-45 myosin chaperone B
chr8_-_14179798 1.11 ENSDART00000040645
ENSDART00000146749
rhoaa
ras homolog gene family, member Aa
chr12_-_43664682 1.09 ENSDART00000159423
foxi1
forkhead box i1
chr4_+_65649267 1.08 ENSDART00000184068
si:dkey-205i10.1
si:dkey-205i10.1
chr17_+_38255105 1.05 ENSDART00000005296
nkx2.9
NK2 transcription factor related, locus 9 (Drosophila)
chr11_-_11910225 1.05 ENSDART00000159922
si:ch211-69b7.6
si:ch211-69b7.6
chr14_-_32744464 1.04 ENSDART00000075617
sox3
SRY (sex determining region Y)-box 3
chr4_-_63848305 1.02 ENSDART00000097308
BX901974.1

chr10_-_31562695 1.01 ENSDART00000186456
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr12_+_15290800 1.01 ENSDART00000145656
med1
mediator complex subunit 1
chr22_-_3152357 1.00 ENSDART00000170983
lmnb2
lamin B2
chr16_+_8716800 0.99 ENSDART00000124693
ENSDART00000181961
cabz01093075.1
cabz01093075.1
chr5_+_34623107 0.98 ENSDART00000184126
enc1
ectodermal-neural cortex 1
chr17_-_31164219 0.96 ENSDART00000055754
pkdccb
protein kinase domain containing, cytoplasmic b
chr14_+_6605675 0.95 ENSDART00000143179
adam19b
ADAM metallopeptidase domain 19b
chr4_-_20118468 0.95 ENSDART00000078587
si:dkey-159a18.1
si:dkey-159a18.1
chr14_-_26177156 0.95 ENSDART00000014149
fat2
FAT atypical cadherin 2
chr3_-_40528333 0.93 ENSDART00000193047
actb2
actin, beta 2
chr3_-_32925476 0.93 ENSDART00000189673
aoc2
amine oxidase, copper containing 2
chr13_+_44495063 0.92 ENSDART00000169591
CU694264.1

chr20_+_34374735 0.91 ENSDART00000144090
si:dkeyp-11g8.3
si:dkeyp-11g8.3
chr9_+_17438765 0.90 ENSDART00000138953
rgcc
regulator of cell cycle
chr20_-_43723860 0.89 ENSDART00000122051
mixl1
Mix paired-like homeobox
chr5_+_37837245 0.89 ENSDART00000171617
epd
ependymin
chr9_+_21243985 0.88 ENSDART00000131586
si:rp71-68n21.12
si:rp71-68n21.12
chr4_-_60312069 0.88 ENSDART00000167207
si:dkey-248e17.4
si:dkey-248e17.4
chr13_+_33024547 0.88 ENSDART00000057377
arg2
arginase 2
chr4_+_65537216 0.87 ENSDART00000181458
si:dkey-205i10.1
si:dkey-205i10.1
chr3_-_34656745 0.87 ENSDART00000144824
znfl1
zinc finger-like gene 1
chr21_-_2217685 0.87 ENSDART00000159315
si:dkey-50i6.5
si:dkey-50i6.5
chr19_-_20148469 0.87 ENSDART00000134476
si:ch211-155k24.1
si:ch211-155k24.1
chr24_-_18919562 0.85 ENSDART00000144244
ENSDART00000106188
ENSDART00000182518
cpa6
carboxypeptidase A6
chr7_+_32369463 0.84 ENSDART00000180544
lgr4
leucine-rich repeat containing G protein-coupled receptor 4
chr19_+_47311869 0.83 ENSDART00000136647
ext1c
exostoses (multiple) 1c
chr1_-_52497834 0.82 ENSDART00000136469
ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr4_-_11580948 0.81 ENSDART00000049066
net1
neuroepithelial cell transforming 1
chr4_-_52381070 0.80 ENSDART00000139248
CR318589.2

chr4_+_54519511 0.79 ENSDART00000161653
znf974
zinc finger protein 974
chr9_-_31763246 0.79 ENSDART00000114742
si:dkey-250i3.3
si:dkey-250i3.3
chr12_-_34887943 0.78 ENSDART00000027379
bicral
BRD4 interacting chromatin remodeling complex associated protein like
chr17_+_4408809 0.77 ENSDART00000113401
si:zfos-364h11.1
si:zfos-364h11.1
chr10_-_31563049 0.75 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr10_-_13116337 0.73 ENSDART00000164568
musk
muscle, skeletal, receptor tyrosine kinase
chr25_-_11026907 0.72 ENSDART00000156846
mespbb
mesoderm posterior bb
chr18_+_23373683 0.72 ENSDART00000001102
ENSDART00000189030
mctp2a
multiple C2 domains, transmembrane 2a
chr4_-_60049792 0.71 ENSDART00000158199
znf1033
zinc finger protein 1033
chr14_-_9673601 0.71 ENSDART00000188337
CR792437.1

chr12_+_25600685 0.71 ENSDART00000077157
six3b
SIX homeobox 3b
chr5_+_22791686 0.71 ENSDART00000014806
npas2
neuronal PAS domain protein 2
chr4_+_77740228 0.70 ENSDART00000193397
si:zfos-2131b9.2
si:zfos-2131b9.2
chr4_-_65747476 0.69 ENSDART00000142421
si:dkey-28k24.2
si:dkey-28k24.2
chr8_-_22508055 0.69 ENSDART00000101616
si:ch211-261n11.5
si:ch211-261n11.5
chr15_+_42397125 0.69 ENSDART00000169751
tiam1b
T cell lymphoma invasion and metastasis 1b
chr19_-_5332784 0.68 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr4_-_23839789 0.68 ENSDART00000143571
usp6nl
USP6 N-terminal like
chr5_-_46896541 0.68 ENSDART00000133240
edil3a
EGF-like repeats and discoidin I-like domains 3a
chr23_-_10175898 0.67 ENSDART00000146185
krt5
keratin 5
chr7_+_15324830 0.66 ENSDART00000189088
mespaa
mesoderm posterior aa
chr17_+_58211 0.66 ENSDART00000157642
si:ch1073-209e23.1
si:ch1073-209e23.1
chr16_+_40301056 0.65 ENSDART00000058578
rspo3
R-spondin 3
chr13_+_4205724 0.64 ENSDART00000134105
dlk2
delta-like 2 homolog (Drosophila)
chr19_-_5369486 0.63 ENSDART00000105004
krt17
keratin 17
chr2_+_29795833 0.62 ENSDART00000056750
si:ch211-207d6.2
si:ch211-207d6.2
chr4_+_9028819 0.60 ENSDART00000102893
aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr5_+_34622320 0.59 ENSDART00000141338
enc1
ectodermal-neural cortex 1
chr3_+_34140507 0.59 ENSDART00000131802
si:dkey-204f11.64
si:dkey-204f11.64
chr22_+_11857356 0.58 ENSDART00000179540
mras
muscle RAS oncogene homolog
chr13_-_36535128 0.58 ENSDART00000043312
srsf5a
serine/arginine-rich splicing factor 5a
chr15_+_32711663 0.58 ENSDART00000157854
ENSDART00000167515
postnb
periostin, osteoblast specific factor b
chr14_-_2979878 0.57 ENSDART00000031211
bicc2
bicaudal C homolog 2
chr13_+_27232848 0.57 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr9_-_42873700 0.55 ENSDART00000125953
ttn.1
titin, tandem duplicate 1
chr7_+_57836841 0.55 ENSDART00000136175
camk2d1
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr13_-_37127970 0.55 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr12_+_29236274 0.55 ENSDART00000006505
mxtx2
mix-type homeobox gene 2
chr20_+_17739923 0.54 ENSDART00000024627
cdh2
cadherin 2, type 1, N-cadherin (neuronal)
chr21_+_26726936 0.54 ENSDART00000065392
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr3_-_25814097 0.52 ENSDART00000169706
ntn1b
netrin 1b
chr25_-_17579701 0.52 ENSDART00000073684
mmp15a
matrix metallopeptidase 15a
chr6_+_28877306 0.51 ENSDART00000065137
ENSDART00000123189
ENSDART00000065135
ENSDART00000181512
ENSDART00000130799
tp63
tumor protein p63
chr17_+_24851951 0.50 ENSDART00000180746
cx35.4
connexin 35.4
chr5_-_44843738 0.50 ENSDART00000003926
fbp1a
fructose-1,6-bisphosphatase 1a
chr4_-_39111612 0.50 ENSDART00000150394
si:dkey-122c11.8
si:dkey-122c11.8
chr7_-_7420301 0.49 ENSDART00000102620
six7
SIX homeobox 7
chr14_-_28567845 0.49 ENSDART00000126095
insb
preproinsulin b
chr18_+_7591381 0.49 ENSDART00000136313
si:dkeyp-1h4.6
si:dkeyp-1h4.6
chr3_+_28939759 0.48 ENSDART00000141904
lgals1l1
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr5_+_42467867 0.47 ENSDART00000172028
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr4_+_11384891 0.47 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr20_+_35857399 0.46 ENSDART00000102611
cd2ap
CD2-associated protein
chr8_+_23245596 0.46 ENSDART00000143313
si:ch211-196c10.11
si:ch211-196c10.11
chr12_-_4317165 0.46 ENSDART00000098041
zgc:153760
zgc:153760
chr11_+_7264457 0.46 ENSDART00000154182
reep6
receptor accessory protein 6
chr23_-_46020226 0.46 ENSDART00000160010
SYDE2
synapse defective Rho GTPase homolog 2
chr8_+_8459192 0.46 ENSDART00000140942
ENSDART00000014939
comta
catechol-O-methyltransferase a
chr19_+_7735157 0.46 ENSDART00000186717
tuft1b
tuftelin 1b
chr22_+_1300587 0.45 ENSDART00000124161
si:ch73-138e16.5
si:ch73-138e16.5
chr25_-_32751982 0.45 ENSDART00000012862
isl2a
ISL LIM homeobox 2a
chr11_+_1796426 0.45 ENSDART00000173330
lrp1aa
low density lipoprotein receptor-related protein 1Aa
chr4_-_12323228 0.44 ENSDART00000081089
il17ra1a
interleukin 17 receptor A1a
chr3_+_34121156 0.43 ENSDART00000174929
aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr24_+_39158283 0.43 ENSDART00000053139
atp6v0cb
ATPase H+ transporting V0 subunit cb
chr15_-_32131 0.43 ENSDART00000099074
ENSDART00000164323
CYP2C9
si:zfos-411a11.2
chr1_+_34696503 0.42 ENSDART00000186106
CR339054.2

chr19_-_32600638 0.42 ENSDART00000143497
zgc:91944
zgc:91944
chr3_-_61205711 0.42 ENSDART00000055062
pvalb1
parvalbumin 1
chr15_+_32711172 0.41 ENSDART00000163936
ENSDART00000168135
postnb
periostin, osteoblast specific factor b
chr4_+_64562090 0.41 ENSDART00000188810
si:ch211-223a21.3
si:ch211-223a21.3
chr14_-_34771864 0.41 ENSDART00000141157
ablim3
actin binding LIM protein family, member 3
chr22_-_34872533 0.41 ENSDART00000167176
slit1b
slit homolog 1b (Drosophila)
chr3_-_15451097 0.40 ENSDART00000163836
BX784026.1
Danio rerio linker for activation of T cells (lat), mRNA.
chr20_-_8110672 0.40 ENSDART00000113993
si:ch211-232i5.1
si:ch211-232i5.1
chr7_-_51032128 0.40 ENSDART00000182781
ENSDART00000121574
col4a6
collagen, type IV, alpha 6
chr12_-_16720196 0.40 ENSDART00000187639
si:dkey-26g8.4
si:dkey-26g8.4
chr2_+_33368414 0.39 ENSDART00000077462
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr4_+_36656541 0.39 ENSDART00000181349
si:dkey-151g22.1
si:dkey-151g22.1
chr25_+_36327034 0.39 ENSDART00000073452
zgc:110216
zgc:110216
chr12_-_16595177 0.39 ENSDART00000133962
si:dkey-239j18.2
si:dkey-239j18.2
chr2_-_47431205 0.38 ENSDART00000014350
ENSDART00000038828
pax3a
paired box 3a
chr20_-_7128612 0.38 ENSDART00000146755
ENSDART00000036871
si:ch211-121a2.4
si:ch211-121a2.4
chr22_+_16497670 0.38 ENSDART00000014330
ier5
immediate early response 5
chr7_-_38638809 0.38 ENSDART00000144341
c6ast4
six-cysteine containing astacin protease 4
chr7_-_48667056 0.37 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr8_-_28449782 0.36 ENSDART00000062702
cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr3_-_60288533 0.36 ENSDART00000181981
ENSDART00000193313
si:ch211-214b16.3
si:ch211-214b16.3
chr13_+_45332203 0.36 ENSDART00000110466
si:ch211-168h21.3
si:ch211-168h21.3
chr10_-_32524035 0.36 ENSDART00000137608
dgat2
diacylglycerol O-acyltransferase 2
chr15_+_42599501 0.35 ENSDART00000177646
grik1b
glutamate receptor, ionotropic, kainate 1b
chr4_-_42221141 0.35 ENSDART00000160521
si:ch211-129p6.2
si:ch211-129p6.2
chr5_-_68795063 0.35 ENSDART00000016307
her1
hairy-related 1
chr12_+_31616412 0.35 ENSDART00000124439
cpn1
carboxypeptidase N, polypeptide 1
chr19_+_14921000 0.35 ENSDART00000144052
oprd1a
opioid receptor, delta 1a
chr16_-_13921589 0.35 ENSDART00000023543
rcvrn2
recoverin 2
chr19_-_5769553 0.34 ENSDART00000175003
si:ch211-264f5.6
si:ch211-264f5.6
chr11_-_30352333 0.34 ENSDART00000030794
tmem169a
transmembrane protein 169a
chr10_+_21899753 0.34 ENSDART00000080155
hrh2b
histamine receptor H2b
chr7_-_51476276 0.34 ENSDART00000082464
nhsl2
NHS-like 2
chr14_-_25042184 0.34 ENSDART00000131027
TMEM216
si:rp71-1d10.5
chr13_+_27232694 0.34 ENSDART00000131128
rin2
Ras and Rab interactor 2
chr4_+_77735212 0.34 ENSDART00000160716
si:dkey-238k10.1
si:dkey-238k10.1
chr4_+_37952218 0.33 ENSDART00000186865
si:dkeyp-82b4.2
si:dkeyp-82b4.2
chr2_+_48288461 0.33 ENSDART00000141495
hes6
hes family bHLH transcription factor 6
chr2_+_16453769 0.33 ENSDART00000100307
zgc:110269
zgc:110269
chr24_+_22022109 0.33 ENSDART00000133686
ropn1l
rhophilin associated tail protein 1-like
chr4_+_64981411 0.33 ENSDART00000157798
CT955963.1

chr19_+_38422059 0.32 ENSDART00000035093
col9a2
procollagen, type IX, alpha 2
chr13_+_24280380 0.32 ENSDART00000184115
acta1b
actin, alpha 1b, skeletal muscle
chr20_+_305035 0.31 ENSDART00000104807
si:dkey-119m7.4
si:dkey-119m7.4
chr7_+_65673885 0.31 ENSDART00000169182
parvab
parvin, alpha b
chr4_-_56151174 0.31 ENSDART00000125904
znf986
zinc finger protein 986
chr19_-_22621811 0.31 ENSDART00000090669
pleca
plectin a
chr5_+_54501105 0.31 ENSDART00000165889
tprn
taperin
chr4_-_20051141 0.30 ENSDART00000066963
atp6v1f
ATPase H+ transporting V1 subunit F
chr14_+_7932973 0.30 ENSDART00000109941
cxxc5b
CXXC finger protein 5b
chr12_-_32013125 0.30 ENSDART00000153355
grin2cb
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
chr21_+_25765734 0.29 ENSDART00000021664
cldnb
claudin b

Network of associatons between targets according to the STRING database.

First level regulatory network of tbx15_tbx1_mgaa_tbx4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.7 2.9 GO:0048338 axial mesoderm structural organization(GO:0048331) mesoderm structural organization(GO:0048338)
0.7 2.6 GO:0009957 epidermal cell fate specification(GO:0009957)
0.6 2.5 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.6 3.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.5 1.5 GO:0098725 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
0.5 1.4 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.5 6.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 2.6 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.3 2.1 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.2 3.5 GO:0060325 face morphogenesis(GO:0060325)
0.2 2.3 GO:0035587 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2 0.6 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 2.6 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.2 0.6 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.2 1.1 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.2 0.5 GO:0046351 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.2 1.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 1.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.8 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.5 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 1.4 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 1.7 GO:0003128 heart field specification(GO:0003128)
0.1 0.8 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 0.4 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 0.7 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.3 GO:0048389 intermediate mesoderm development(GO:0048389)
0.1 2.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 1.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.5 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 0.3 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.7 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.5 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 0.2 GO:0015911 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.1 1.8 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.5 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 0.6 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 2.2 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.4 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 1.0 GO:0016203 muscle attachment(GO:0016203)
0.1 0.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.3 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 0.8 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.1 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.5 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 1.0 GO:0043049 otic placode formation(GO:0043049)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 1.2 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0 0.2 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.0 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 1.5 GO:0001706 endoderm formation(GO:0001706)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:1903011 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.0 0.1 GO:0032640 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.0 0.1 GO:0034672 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.0 1.1 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.6 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.2 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.0 0.2 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.9 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.3 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.5 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0050936 xanthophore differentiation(GO:0050936)
0.0 0.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.2 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 2.6 GO:0031101 fin regeneration(GO:0031101)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677) positive regulation of calcium ion import(GO:0090280)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.2 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.8 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.3 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0002370 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of interferon-gamma production(GO:0032729) positive regulation of mast cell activation(GO:0033005) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.2 GO:2000826 regulation of heart morphogenesis(GO:2000826)
0.0 0.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.2 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.2 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 1.5 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0060079 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 0.1 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.1 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 1.6 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.0 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.2 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.2 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.5 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.0 GO:0032925 regulation of activin receptor signaling pathway(GO:0032925)
0.0 0.1 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.4 GO:0001878 response to yeast(GO:0001878)
0.0 0.0 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 1.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.0 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.0 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.9 GO:0006006 glucose metabolic process(GO:0006006)
0.0 1.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.1 GO:0042311 vasodilation(GO:0042311)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.0 GO:0043034 costamere(GO:0043034)
0.2 0.9 GO:0097433 dense body(GO:0097433)
0.1 0.7 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.4 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.0 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.6 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.7 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0014704 intercalated disc(GO:0014704)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 3.8 GO:0005882 intermediate filament(GO:0005882)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.1 GO:0031672 A band(GO:0031672)
0.0 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 2.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0098978 glutamatergic synapse(GO:0098978)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:1901612 cardiolipin binding(GO:1901612)
0.6 2.6 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.3 2.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 1.7 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.2 0.8 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 0.6 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 1.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 0.9 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.2 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 2.0 GO:0004046 aminoacylase activity(GO:0004046)
0.2 0.5 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.3 GO:0038046 enkephalin receptor activity(GO:0038046)
0.1 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 2.2 GO:0005112 Notch binding(GO:0005112)
0.1 1.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.7 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.1 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 9.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.5 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 1.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.6 GO:0098918 structural constituent of synapse(GO:0098918)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 4.3 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.1 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 1.0 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0032028 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 1.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.9 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.1 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 3.9 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 1.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 3.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis