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PRJNA195909:zebrafish embryo and larva development

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Results for tbx3a+tbx3b

Z-value: 1.65

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Transcription factors associated with tbx3a+tbx3b

Gene Symbol Gene ID Gene Info
tbx3a
ENSDARG00000002216 T-box transcription factor 3a
tbx3b
ENSDARG00000061509 T-box transcription factor 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbx3adr11_v1_chr5_-_72324371_723243710.872.6e-03Click!
tbx3bdr11_v1_chr5_+_26913120_269131200.599.3e-02Click!

Activity profile of tbx3a+tbx3b motif

Sorted Z-values of tbx3a+tbx3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_41990421 3.28 ENSDART00000055921
pycard
PYD and CARD domain containing
chr24_-_26283359 3.18 ENSDART00000128618
and1
actinodin1
chr12_+_27141140 2.98 ENSDART00000136415
hoxb1b
homeobox B1b
chr6_+_15250672 2.86 ENSDART00000155951
si:ch73-23l24.1
si:ch73-23l24.1
chr10_-_29903165 2.83 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr8_+_26818446 2.65 ENSDART00000134987
ENSDART00000138835
si:ch211-156j16.1
si:ch211-156j16.1
chr7_-_73752955 2.61 ENSDART00000171254
ENSDART00000009888
casq1b
calsequestrin 1b
chr12_-_26406323 2.56 ENSDART00000131896
myoz1b
myozenin 1b
chr20_-_26532167 2.33 ENSDART00000061914
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr18_+_37272568 2.20 ENSDART00000132749
tmem123
transmembrane protein 123
chr21_+_25688388 2.09 ENSDART00000125709
bicdl2
bicaudal-D-related protein 2
chr8_-_46897734 2.02 ENSDART00000138125
hes2.2
hes family bHLH transcription factor 2, tandem duplicate 2
chr24_-_26479841 1.99 ENSDART00000079984
rpl22l1
ribosomal protein L22-like 1
chr11_-_23219367 1.98 ENSDART00000003646
optc
opticin
chr25_-_13188678 1.97 ENSDART00000125754
si:ch211-147m6.1
si:ch211-147m6.1
chr19_-_10810006 1.95 ENSDART00000151157
si:dkey-3n22.9
si:dkey-3n22.9
chr23_-_20345473 1.95 ENSDART00000140935
si:rp71-17i16.6
si:rp71-17i16.6
chr10_-_15048781 1.89 ENSDART00000038401
ENSDART00000155674
si:ch211-95j8.2
si:ch211-95j8.2
chr5_-_17601759 1.85 ENSDART00000138387
si:ch211-130h14.6
si:ch211-130h14.6
chr9_+_30108641 1.83 ENSDART00000060174
jagn1a
jagunal homolog 1a
chr13_-_37180815 1.80 ENSDART00000139907
si:dkeyp-77c8.1
si:dkeyp-77c8.1
chr10_+_21656654 1.73 ENSDART00000160464
pcdh1g2
protocadherin 1 gamma 2
chr13_-_32635859 1.64 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matn3b
matrilin 3b
chr24_-_23942722 1.63 ENSDART00000080810
arxa
aristaless related homeobox a
chr17_+_8175998 1.60 ENSDART00000131200
myct1b
myc target 1b
chr22_-_5441893 1.57 ENSDART00000161421
zgc:194627
zgc:194627
chr14_-_28052474 1.54 ENSDART00000172948
ENSDART00000135337
TSC22D3 (1 of many)
zgc:64189
si:ch211-220e11.3
zgc:64189
chr2_+_23482798 1.49 ENSDART00000187448
BX470197.1

chr17_-_27273296 1.40 ENSDART00000077087
id3
inhibitor of DNA binding 3
chr23_-_5683147 1.38 ENSDART00000102766
ENSDART00000067351
tnnt2a
troponin T type 2a (cardiac)
chr21_-_20725853 1.36 ENSDART00000114502
si:ch211-22d5.2
si:ch211-22d5.2
chr8_+_23521974 1.35 ENSDART00000188130
ENSDART00000129378
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr16_-_32184460 1.31 ENSDART00000102027
kpna5
karyopherin alpha 5 (importin alpha 6)
chr4_+_15899668 1.28 ENSDART00000101592
col7a1l
collagen type VII alpha 1-like
chr24_-_24163201 1.26 ENSDART00000140170
map7d2b
MAP7 domain containing 2b
chr8_-_32894203 1.24 ENSDART00000147822
si:dkey-56i24.1
si:dkey-56i24.1
chr24_-_7697274 1.17 ENSDART00000186077
syt5b
synaptotagmin Vb
chr24_-_24162930 1.15 ENSDART00000080602
map7d2b
MAP7 domain containing 2b
chr8_-_25336589 1.13 ENSDART00000009682
atp5pb
ATP synthase peripheral stalk-membrane subunit b
chr5_+_69278089 1.12 ENSDART00000136656
selenom
selenoprotein M
chr5_-_60159116 1.12 ENSDART00000147675
si:dkey-280e8.1
si:dkey-280e8.1
chr21_+_22423286 1.11 ENSDART00000133190
capslb
calcyphosine-like b
chr4_-_16001118 1.10 ENSDART00000041070
ENSDART00000125389
mest
mesoderm specific transcript
chr7_-_33960170 1.09 ENSDART00000180766
skor1a
SKI family transcriptional corepressor 1a
chr25_-_35599887 1.08 ENSDART00000153827
clpxb
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr21_-_45613564 1.07 ENSDART00000160324
LO018363.1

chr13_-_32577386 1.06 ENSDART00000016535
kcns3a
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a
chr10_-_24362775 1.02 ENSDART00000182104
pitpnab
phosphatidylinositol transfer protein, alpha b
chr12_+_32159272 1.01 ENSDART00000153167
hlfb
hepatic leukemia factor b
chr2_+_7849890 1.01 ENSDART00000114241
si:ch211-38m6.6
si:ch211-38m6.6
chr9_-_23156908 1.00 ENSDART00000135461
lypd6b
LY6/PLAUR domain containing 6B
chr12_+_20583552 0.99 ENSDART00000170035
arsg
arylsulfatase G
chr6_-_21988375 0.97 ENSDART00000161257
plxnb1b
plexin b1b
chr18_+_29145681 0.93 ENSDART00000089031
ENSDART00000193336
ppfibp2a
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr14_+_46287296 0.86 ENSDART00000183620
cabp2b
calcium binding protein 2b
chr2_+_20472150 0.84 ENSDART00000168537
agla
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase a
chr24_-_31306724 0.83 ENSDART00000165399
acp5b
acid phosphatase 5b, tartrate resistant
chr20_-_909953 0.80 ENSDART00000011283
cnr1
cannabinoid receptor 1
chr8_-_50979047 0.78 ENSDART00000184788
ENSDART00000180906
zgc:91909
zgc:91909
chr1_-_45177373 0.78 ENSDART00000143142
ENSDART00000034549
zgc:111983
zgc:111983
chr19_+_18493782 0.78 ENSDART00000160992
fkbp10a
FK506 binding protein 10a
chr16_+_14588141 0.78 ENSDART00000140469
ENSDART00000059984
ENSDART00000167411
ENSDART00000133566
deptor
DEP domain containing MTOR-interacting protein
chr18_+_48943875 0.77 ENSDART00000076803
FO681288.1

chr1_-_38813679 0.75 ENSDART00000148917
asb5b
ankyrin repeat and SOCS box containing 5b
chr20_+_34582276 0.74 ENSDART00000185185
si:ch211-242b18.1
si:ch211-242b18.1
chr11_+_1657221 0.71 ENSDART00000164394
lrp1aa
low density lipoprotein receptor-related protein 1Aa
chr22_+_567733 0.69 ENSDART00000171036
usp49
ubiquitin specific peptidase 49
chr4_+_76431531 0.66 ENSDART00000174278
FP074874.1

chr14_+_20911310 0.64 ENSDART00000160318
lygl2
lysozyme g-like 2
chr6_-_1514767 0.62 ENSDART00000067586
chchd6b
coiled-coil-helix-coiled-coil-helix domain containing 6b
chr4_+_43700319 0.60 ENSDART00000141967
si:ch211-226o13.1
si:ch211-226o13.1
chr5_-_10236599 0.59 ENSDART00000099834
si:ch73-42k18.1
si:ch73-42k18.1
chr14_-_3032016 0.58 ENSDART00000183461
ENSDART00000183035
ndst1a
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a
chr13_+_3954540 0.57 ENSDART00000092646
lrrc73
leucine rich repeat containing 73
chr19_-_23674904 0.54 ENSDART00000187300
BX927234.2

chr21_+_21611867 0.54 ENSDART00000189148
b9d2
B9 domain containing 2
chr14_-_3031810 0.52 ENSDART00000090213
ndst1a
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a
chr3_+_17314997 0.52 ENSDART00000139763
stat5a
signal transducer and activator of transcription 5a
chr7_+_2236317 0.52 ENSDART00000075859
zgc:172065
zgc:172065
chr20_-_34164278 0.52 ENSDART00000153128
hmcn1
hemicentin 1
chr10_-_14536399 0.51 ENSDART00000186501
hdhd2
haloacid dehalogenase-like hydrolase domain containing 2
chr21_+_21612214 0.50 ENSDART00000008099
b9d2
B9 domain containing 2
chr4_-_9728730 0.49 ENSDART00000150265
mical3b
microtubule associated monooxygenase, calponin and LIM domain containing 3b
chr23_+_2421689 0.48 ENSDART00000180200
tcp1
t-complex 1
chr12_-_26415499 0.48 ENSDART00000185779
synpo2lb
synaptopodin 2-like b
chr7_+_13756215 0.47 ENSDART00000172804
ENSDART00000018801
ENSDART00000115054
rasl12
RAS-like, family 12
chr1_+_56502706 0.47 ENSDART00000188665
CABZ01059403.1

chr4_+_77681389 0.44 ENSDART00000099727
gbp4
guanylate binding protein 4
chr13_+_3954715 0.44 ENSDART00000182477
ENSDART00000192142
ENSDART00000190962
lrrc73
leucine rich repeat containing 73
chr2_-_43745146 0.43 ENSDART00000056164
ENSDART00000098052
ftr96
finTRIM family, member 96
chr9_-_25094181 0.43 ENSDART00000132160
rubcnl
RUN and cysteine rich domain containing beclin 1 interacting protein like
chr25_-_27819838 0.42 ENSDART00000067106
lmod2a
leiomodin 2 (cardiac) a
chr15_-_21678634 0.39 ENSDART00000061139
bco2b
beta-carotene oxygenase 2b
chr14_+_23687678 0.39 ENSDART00000002469
hspa4b
heat shock protein 4b
chr4_+_121709 0.39 ENSDART00000186461
ENSDART00000172255
crebl2
cAMP responsive element binding protein-like 2
chr2_+_27403300 0.38 ENSDART00000099180
elovl8a
ELOVL fatty acid elongase 8a
chr5_+_69868911 0.37 ENSDART00000014649
ENSDART00000188215
ENSDART00000167385
ugt2a5
UDP glucuronosyltransferase 2 family, polypeptide A5
chr3_-_26341959 0.37 ENSDART00000169344
ENSDART00000142878
ENSDART00000087196
zgc:153240
zgc:153240
chr8_+_20918207 0.37 ENSDART00000144039
si:ch73-196i15.5
si:ch73-196i15.5
chr18_-_16392448 0.36 ENSDART00000180253
mgat4c
mgat4 family, member C
chr22_-_9649627 0.35 ENSDART00000164721
si:dkey-286j17.4
si:dkey-286j17.4
chr13_+_25486608 0.34 ENSDART00000057689
bag3
BCL2 associated athanogene 3
chr15_-_38154616 0.34 ENSDART00000099392
irgq2
immunity-related GTPase family, q2
chr12_+_20506197 0.34 ENSDART00000153010
si:zfos-754c12.2
si:zfos-754c12.2
chr24_-_21487609 0.33 ENSDART00000191325
atp8a2
ATPase phospholipid transporting 8A2
chr5_+_69856153 0.33 ENSDART00000124128
ENSDART00000073663
ugt2a6
UDP glucuronosyltransferase 2 family, polypeptide A6
chr5_-_22501663 0.32 ENSDART00000133174
si:dkey-27p18.5
si:dkey-27p18.5
chr4_+_77908076 0.32 ENSDART00000168811
si:zfos-2131b9.2
si:zfos-2131b9.2
chr21_+_21655755 0.32 ENSDART00000079524
or125-8
odorant receptor, family E, subfamily 125, member 8
chr13_+_1089942 0.32 ENSDART00000054322
cnrip1b
cannabinoid receptor interacting protein 1b
chr15_-_28200049 0.31 ENSDART00000004200
sarm1
sterile alpha and TIR motif containing 1
chr23_-_15090782 0.30 ENSDART00000133624
si:ch211-218g4.2
si:ch211-218g4.2
chr16_+_32029090 0.30 ENSDART00000041054
tmc4
transmembrane channel-like 4
chr4_-_18775548 0.30 ENSDART00000141187
def6c
differentially expressed in FDCP 6c homolog
chr12_+_36109071 0.28 ENSDART00000171268
map2k6
mitogen-activated protein kinase kinase 6
chr12_+_18663154 0.28 ENSDART00000057918
si:ch211-147h1.4
si:ch211-147h1.4
chr20_+_53577502 0.26 ENSDART00000126983
myh6
myosin, heavy chain 6, cardiac muscle, alpha
chr24_+_35947077 0.25 ENSDART00000173406
obscnb
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr5_-_51148298 0.23 ENSDART00000042420
ccdc180
coiled-coil domain containing 180
chr19_+_9212031 0.23 ENSDART00000052930
ndufv1
NADH dehydrogenase (ubiquinone) flavoprotein 1
chr13_-_51903150 0.22 ENSDART00000090644
mrpl2
mitochondrial ribosomal protein L2
chr20_+_51464670 0.21 ENSDART00000150110
thbd
thrombomodulin
chr7_+_22702437 0.21 ENSDART00000182054
si:dkey-165a24.9
si:dkey-165a24.9
chr4_-_49987980 0.20 ENSDART00000150428
si:dkey-156k2.4
si:dkey-156k2.4
chr2_+_6734108 0.20 ENSDART00000112227
brinp3b
bone morphogenetic protein/retinoic acid inducible neural-specific 3b
chr24_-_25184553 0.20 ENSDART00000166917
plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr25_-_15496485 0.18 ENSDART00000140245
si:dkeyp-67e1.6
si:dkeyp-67e1.6
chr13_+_33304187 0.18 ENSDART00000075826
ENSDART00000145295
dcdc2b
doublecortin domain containing 2B
chr4_-_60518031 0.17 ENSDART00000157489
si:dkey-211i20.4
si:dkey-211i20.4
chr12_+_31537604 0.16 ENSDART00000153340
si:ch73-205h11.1
si:ch73-205h11.1
chr4_-_75812937 0.16 ENSDART00000125096
si:ch211-203c5.3
si:ch211-203c5.3
chr21_-_27195256 0.15 ENSDART00000133152
ENSDART00000065401
zgc:110782
zgc:110782
chr7_+_13756374 0.15 ENSDART00000180808
rasl12
RAS-like, family 12
chr4_+_53246788 0.15 ENSDART00000184708
ENSDART00000169256
si:dkey-250k10.1
si:dkey-250k10.1
chr7_+_22702225 0.13 ENSDART00000173672
si:dkey-165a24.9
si:dkey-165a24.9
chr22_-_9157364 0.13 ENSDART00000182762
si:ch211-213a13.5
si:ch211-213a13.5
chr3_-_33967767 0.12 ENSDART00000151493
ENSDART00000151160
ighv1-4
immunoglobulin heavy variable 1-4
chr16_-_50918908 0.11 ENSDART00000108744
CU855821.1

chr2_-_51611344 0.09 ENSDART00000158137
si:ch211-9d9.8
si:ch211-9d9.8
chr17_-_47090440 0.08 ENSDART00000163542
CABZ01056321.1

chr3_+_5297493 0.08 ENSDART00000138596
si:ch211-150d5.3
si:ch211-150d5.3
chr15_-_28860282 0.06 ENSDART00000156738
gpr4
G protein-coupled receptor 4
chr13_-_11984867 0.06 ENSDART00000157538
npm3
nucleophosmin/nucleoplasmin, 3
chr16_-_14587332 0.06 ENSDART00000012479
dscc1
DNA replication and sister chromatid cohesion 1
chr25_-_15504559 0.05 ENSDART00000139294
BX323543.5

chr25_-_15512819 0.05 ENSDART00000142684
si:dkeyp-67e1.2
si:dkeyp-67e1.2
chr22_+_2451732 0.04 ENSDART00000164419
znf1177
zinc finger protein 1177
chr5_+_29803380 0.04 ENSDART00000005263
ENSDART00000137558
ENSDART00000146963
ENSDART00000134900
usf1l
upstream transcription factor 1, like
chr7_+_56472585 0.03 ENSDART00000135259
ENSDART00000073596
ist1
increased sodium tolerance 1 homolog (yeast)
chr3_-_2072630 0.03 ENSDART00000189404
BX005442.3

chr1_-_2453174 0.02 ENSDART00000055779
ENSDART00000152555
ggact.2
ggact.3
gamma-glutamylamine cyclotransferase, tandem duplicate 2
gamma-glutamylamine cyclotransferase, tandem duplicate 3
chr4_+_76906112 0.02 ENSDART00000180696
si:dkey-240n22.6
si:dkey-240n22.6

Network of associatons between targets according to the STRING database.

First level regulatory network of tbx3a+tbx3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.6 1.8 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.5 2.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.4 3.0 GO:0021570 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.4 1.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 1.4 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.2 0.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 2.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.3 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.1 1.0 GO:0036372 opsin transport(GO:0036372)
0.1 0.3 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 0.4 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.1 1.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.3 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 1.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.8 GO:2000253 cannabinoid signaling pathway(GO:0038171) positive regulation of feeding behavior(GO:2000253)
0.1 0.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600) regulation of glucose import(GO:0046324)
0.1 3.3 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 0.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.8 GO:0045453 bone resorption(GO:0045453)
0.1 0.8 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 1.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.1 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 1.1 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 1.0 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.4 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 1.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.2 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 3.7 GO:0033333 fin development(GO:0033333)
0.0 2.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.6 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 1.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0061702 inflammasome complex(GO:0061702)
0.4 2.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 1.2 GO:0031045 dense core granule(GO:0031045)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.0 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 3.4 GO:0030018 Z disc(GO:0030018)
0.0 1.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.3 2.6 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.2 3.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 0.8 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.2 0.8 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 1.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.4 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.4 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 2.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 1.1 GO:0046332 SMAD binding(GO:0046332)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 2.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0010181 NADH dehydrogenase (ubiquinone) activity(GO:0008137) FMN binding(GO:0010181) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 3.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation