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PRJNA195909:zebrafish embryo and larva development

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Results for tcf7

Z-value: 0.77

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Transcription factors associated with tcf7

Gene Symbol Gene ID Gene Info
tcf7
ENSDARG00000038672 transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tcf7dr11_v1_chr21_+_45268112_452681120.215.8e-01Click!

Activity profile of tcf7 motif

Sorted Z-values of tcf7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_21542702 1.47 ENSDART00000146761
ENSDART00000134502
zgc:165539
zgc:165539
chr10_+_19569052 1.41 ENSDART00000058425
CABZ01059627.1

chr4_-_77114795 1.13 ENSDART00000144849
CU467646.2

chr1_+_24376394 1.01 ENSDART00000102542
zgc:171517
zgc:171517
chr12_+_48340133 0.83 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
ddit4
DNA-damage-inducible transcript 4
chr15_-_35930070 0.79 ENSDART00000076229
irs1
insulin receptor substrate 1
chr17_+_24597001 0.74 ENSDART00000191834
rlf
rearranged L-myc fusion
chr12_+_27068525 0.67 ENSDART00000188634
srcap
Snf2-related CREBBP activator protein
chr20_+_4221978 0.65 ENSDART00000171898
ipcef1
interaction protein for cytohesin exchange factors 1
chr5_-_41996414 0.64 ENSDART00000143573
ncor1
nuclear receptor corepressor 1
chr19_-_7033636 0.64 ENSDART00000122815
ENSDART00000123443
ENSDART00000124094
daxx
death-domain associated protein
chr3_-_26190804 0.63 ENSDART00000136001
ypel3
yippee-like 3
chr14_+_1240419 0.60 ENSDART00000181248
adad1
adenosine deaminase domain containing 1 (testis-specific)
chr5_-_23696926 0.57 ENSDART00000021462
rnf128a
ring finger protein 128a
chr9_-_12401871 0.53 ENSDART00000191901
nup35
nucleoporin 35
chr21_-_18275226 0.53 ENSDART00000126672
ENSDART00000135239
brd3a
bromodomain containing 3a
chr4_-_14531687 0.53 ENSDART00000182093
ENSDART00000159447
plxnb2a
plexin b2a
chr21_+_20901505 0.52 ENSDART00000132741
c7b
complement component 7b
chr5_-_28149767 0.50 ENSDART00000051515
zgc:110329
zgc:110329
chr5_+_20453874 0.50 ENSDART00000124545
ENSDART00000008402
sart3
squamous cell carcinoma antigen recognized by T cells 3
chr22_+_12161738 0.49 ENSDART00000168857
ccnt2b
cyclin T2b
chr3_-_29891218 0.48 ENSDART00000142118
slc25a39
solute carrier family 25, member 39
chr2_+_21174998 0.47 ENSDART00000079518
dnajc1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr7_+_35075847 0.47 ENSDART00000193469
ENSDART00000037346
ctrb1
chymotrypsinogen B1
chr7_+_29890292 0.46 ENSDART00000170403
ENSDART00000168600
tln2a
talin 2a
chr5_-_24231139 0.45 ENSDART00000143492
senp3a
SUMO1/sentrin/SMT3 specific peptidase 3a
chr22_+_26804197 0.45 ENSDART00000135688
si:dkey-44g23.2
si:dkey-44g23.2
chr19_+_43037657 0.44 ENSDART00000168263
ENSDART00000184771
ENSDART00000164453
ENSDART00000165202
pum1
pumilio RNA-binding family member 1
chr4_-_2945306 0.44 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr23_-_19977214 0.44 ENSDART00000054659
ccnq
cyclin Q
chr17_+_43595692 0.43 ENSDART00000156271
cfap99
cilia and flagella associated protein 99
chr18_+_38775277 0.43 ENSDART00000186129
fam214a
family with sequence similarity 214, member A
chr7_-_22632938 0.43 ENSDART00000159867
ENSDART00000165706
si:dkey-112a7.4
si:dkey-112a7.4
chr24_+_9696760 0.42 ENSDART00000140200
ENSDART00000187411
topbp1
DNA topoisomerase II binding protein 1
chr21_+_18274825 0.42 ENSDART00000144322
ENSDART00000147768
wdr5
WD repeat domain 5
chr22_+_8753092 0.42 ENSDART00000140720
si:dkey-182g1.2
si:dkey-182g1.2
chr20_-_4031475 0.41 ENSDART00000112053
fam89a
family with sequence similarity 89, member A
chr11_+_44226200 0.40 ENSDART00000191417
gnb4b
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr24_+_37799818 0.40 ENSDART00000131975
telo2
TEL2, telomere maintenance 2, homolog (S. cerevisiae)
chr21_+_13387965 0.40 ENSDART00000134347
zgc:113162
zgc:113162
chr3_+_41558682 0.39 ENSDART00000157023
card11
caspase recruitment domain family, member 11
chr22_+_21549419 0.38 ENSDART00000139411
plpp2b
phospholipid phosphatase 2b
chr23_+_39963599 0.38 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr3_+_15773991 0.38 ENSDART00000089923
znf652
zinc finger protein 652
chr7_-_55454406 0.38 ENSDART00000108646
piezo1
piezo-type mechanosensitive ion channel component 1
chr20_-_23876291 0.38 ENSDART00000043316
katna1
katanin p60 (ATPase containing) subunit A 1
chr7_-_22632518 0.37 ENSDART00000161046
si:dkey-112a7.4
si:dkey-112a7.4
chr13_+_33268657 0.36 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr5_-_37117778 0.36 ENSDART00000149138
il13ra2
interleukin 13 receptor, alpha 2
chr14_+_1240604 0.35 ENSDART00000188258
adad1
adenosine deaminase domain containing 1 (testis-specific)
chr3_-_29891456 0.35 ENSDART00000151677
ENSDART00000014021
slc25a39
solute carrier family 25, member 39
chr1_-_52790724 0.35 ENSDART00000139577
ENSDART00000100937
patl1
protein associated with topoisomerase II homolog 1 (yeast)
chr2_-_43739740 0.34 ENSDART00000113849
kif5ba
kinesin family member 5B, a
chr3_-_23643751 0.34 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr13_+_50778187 0.33 ENSDART00000159597
dntt
deoxynucleotidyltransferase, terminal
chr12_-_11349899 0.33 ENSDART00000079645
zgc:174164
zgc:174164
chr17_-_20695998 0.33 ENSDART00000063613
ccdc6a
coiled-coil domain containing 6a
chr5_-_56964547 0.33 ENSDART00000074400
tia1
TIA1 cytotoxic granule-associated RNA binding protein
chr4_+_16827390 0.32 ENSDART00000113344
kiss2
kisspeptin 2
chr10_+_23099365 0.32 ENSDART00000022170
LTN1
si:dkey-175g6.5
chr3_-_33934788 0.32 ENSDART00000151411
gtf2f1
general transcription factor IIF, polypeptide 1
chr16_-_12097558 0.32 ENSDART00000123142
pex5
peroxisomal biogenesis factor 5
chr23_+_1702624 0.32 ENSDART00000149357
rabggta
Rab geranylgeranyltransferase, alpha subunit
chr1_-_41374117 0.31 ENSDART00000074777
htt
huntingtin
chr18_-_6534357 0.31 ENSDART00000192886
ddx11
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr7_-_22632690 0.31 ENSDART00000165245
si:dkey-112a7.4
si:dkey-112a7.4
chr8_+_17869225 0.31 ENSDART00000080079
slc44a5b
solute carrier family 44, member 5b
chr16_+_7703693 0.31 ENSDART00000125111
ENSDART00000149769
ENSDART00000149752
ENSDART00000081407
cnot10
CCR4-NOT transcription complex, subunit 10
chr18_-_6534516 0.30 ENSDART00000009217
ddx11
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr9_+_19039608 0.30 ENSDART00000055866
chmp2ba
charged multivesicular body protein 2Ba
chr22_+_3045495 0.30 ENSDART00000164061
LO017843.1

chr19_-_18135724 0.30 ENSDART00000186609
cbx3a
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr15_-_23761580 0.30 ENSDART00000137918
bbc3
BCL2 binding component 3
chr19_+_37118547 0.29 ENSDART00000103163
cx30.9
connexin 30.9
chr8_-_4097722 0.29 ENSDART00000135006
cux2b
cut-like homeobox 2b
chr14_+_989733 0.29 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
si:ch73-308l14.2
chr23_-_27061072 0.29 ENSDART00000124482
zgc:66440
zgc:66440
chr17_+_47116500 0.29 ENSDART00000186627
CLIP4
si:dkeyp-47f9.4
chr16_-_12097394 0.28 ENSDART00000103944
pex5
peroxisomal biogenesis factor 5
chr17_+_13664442 0.28 ENSDART00000171689
lrfn5a
leucine rich repeat and fibronectin type III domain containing 5a
chr11_-_23687158 0.28 ENSDART00000189599
pik3c2b
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr4_-_760560 0.27 ENSDART00000103601
agbl5
ATP/GTP binding protein-like 5
chr7_+_39688208 0.27 ENSDART00000189682
tbc1d14
TBC1 domain family, member 14
chr1_-_54706039 0.26 ENSDART00000083633
exosc1
exosome component 1
chr9_-_9228941 0.26 ENSDART00000121665
cbsb
cystathionine-beta-synthase b
chr2_+_37110504 0.25 ENSDART00000132794
ENSDART00000042974
slc1a8b
solute carrier family 1 (glutamate transporter), member 8b
chr9_+_46745348 0.25 ENSDART00000025256
igfbp2b
insulin-like growth factor binding protein 2b
chr9_+_21993092 0.24 ENSDART00000059693
crygm7
crystallin, gamma M7
chr16_-_11859309 0.24 ENSDART00000145754
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr5_+_42124706 0.23 ENSDART00000020044
ENSDART00000156372
shpk
sedoheptulokinase
chr22_-_22301672 0.23 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr18_+_18861359 0.23 ENSDART00000144605
pllp
plasmolipin
chr6_+_46309795 0.23 ENSDART00000154817
si:dkeyp-67f1.1
si:dkeyp-67f1.1
chr3_-_1146497 0.23 ENSDART00000149061
si:ch73-211l13.2
si:ch73-211l13.2
chr5_-_23485161 0.23 ENSDART00000170293
ENSDART00000134069
si:dkeyp-20g2.1
si:dkeyp-20g2.3
si:dkeyp-20g2.1
si:dkeyp-20g2.3
chr10_+_4046448 0.22 ENSDART00000123086
ENSDART00000052268
pitpnb
phosphatidylinositol transfer protein, beta
chr8_-_1266181 0.22 ENSDART00000148654
ENSDART00000149924
cdc14b
cell division cycle 14B
chr17_-_14591764 0.22 ENSDART00000174703
daam1a
dishevelled associated activator of morphogenesis 1a
chr13_+_4440869 0.22 ENSDART00000156323
tbxtb
T-box transcription factor Tb
chr4_-_32192868 0.22 ENSDART00000164675
CR450785.2

chr4_+_9360697 0.22 ENSDART00000128937
ENSDART00000156946
ipo8
importin 8
chr8_+_35356944 0.21 ENSDART00000143243
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr14_+_20941038 0.21 ENSDART00000182539
zgc:66433
zgc:66433
chr10_+_29849497 0.21 ENSDART00000099994
ENSDART00000132212
hspa8
heat shock protein 8
chr13_+_10023256 0.20 ENSDART00000110035
srbd1
S1 RNA binding domain 1
chr24_-_5932982 0.20 ENSDART00000138412
ENSDART00000135124
ENSDART00000007373
acbd5a
acyl-CoA binding domain containing 5a
chr1_-_26023678 0.20 ENSDART00000054202
si:ch211-145b13.5
si:ch211-145b13.5
chr3_+_9071806 0.20 ENSDART00000162372
znf985
zinc finger protein 985
chr16_+_3067134 0.19 ENSDART00000012048
cyb5r4
cytochrome b5 reductase 4
chr15_-_1484795 0.19 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr25_+_3294150 0.19 ENSDART00000030683
tmpob
thymopoietin b
chr4_+_69375564 0.19 ENSDART00000150334
si:dkey-246j6.1
si:dkey-246j6.1
chr5_+_42280372 0.19 ENSDART00000142855
tbx6l
T-box 6, like
chr3_-_26183699 0.18 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr3_-_26978793 0.18 ENSDART00000155396
nubp1
nucleotide binding protein 1 (MinD homolog, E. coli)
chr10_-_11261386 0.18 ENSDART00000189946
ptbp3
polypyrimidine tract binding protein 3
chr12_+_34273240 0.17 ENSDART00000037904
socs3b
suppressor of cytokine signaling 3b
chr5_+_43470544 0.17 ENSDART00000111587
rhobtb2a
Rho-related BTB domain containing 2a
chr1_+_32341484 0.17 ENSDART00000137156
pudp
pseudouridine 5'-phosphatase
chr10_-_11261565 0.16 ENSDART00000146727
ptbp3
polypyrimidine tract binding protein 3
chr4_-_20511595 0.16 ENSDART00000185806
rassf8b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8b
chr4_+_40302769 0.16 ENSDART00000137892
znf993
zinc finger protein 993
chr21_+_10790680 0.16 ENSDART00000144460
znf532
zinc finger protein 532
chr24_+_26017094 0.15 ENSDART00000137851
tfr1b
transferrin receptor 1b
chr11_-_3380959 0.15 ENSDART00000187157
mcrs1
microspherule protein 1
chr3_-_23513155 0.15 ENSDART00000170200
BX682558.1

chr7_-_57509447 0.15 ENSDART00000051973
ENSDART00000147036
sirt3
sirtuin 3
chr5_-_30984010 0.15 ENSDART00000182367
spns3
spinster homolog 3 (Drosophila)
chr5_+_1089600 0.14 ENSDART00000183128
LO017799.1

chr11_-_3381343 0.13 ENSDART00000002545
mcrs1
microspherule protein 1
chr20_+_23315242 0.13 ENSDART00000132248
fryl
furry homolog, like
chr20_-_46061650 0.13 ENSDART00000143078
taar12e
trace amine associated receptor 12e
chr9_+_13733468 0.13 ENSDART00000165954
ENSDART00000160355
ENSDART00000081040
ENSDART00000138254
ENSDART00000081015
ENSDART00000141314
abi2a
abl-interactor 2a
chr4_-_3064101 0.12 ENSDART00000135701
plekha5
pleckstrin homology domain containing, family A member 5
chr5_+_44064764 0.12 ENSDART00000143843
si:dkey-84j12.1
si:dkey-84j12.1
chr18_-_13360106 0.12 ENSDART00000091512
cmip
c-Maf inducing protein
chr9_-_28616436 0.12 ENSDART00000136985
si:ch73-7i4.2
si:ch73-7i4.2
chr17_-_6076266 0.12 ENSDART00000171084
ephx2
epoxide hydrolase 2, cytoplasmic
chr1_-_50293946 0.12 ENSDART00000053028
ENSDART00000125099
tbck
TBC1 domain containing kinase
chr10_+_29849977 0.11 ENSDART00000180242
hspa8
heat shock protein 8
chr7_-_24112484 0.10 ENSDART00000111923
ajuba
ajuba LIM protein
chr9_-_1604601 0.10 ENSDART00000143130
agps
alkylglycerone phosphate synthase
chr19_+_42469058 0.10 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr12_-_979789 0.10 ENSDART00000128188
daglb
diacylglycerol lipase, beta
chr15_-_47822597 0.10 ENSDART00000193236
ENSDART00000161391
CZQB01095947.1

chr12_+_48204891 0.09 ENSDART00000190534
ENSDART00000164427
ndr2
nodal-related 2
chr4_-_50759477 0.09 ENSDART00000150246
si:ch211-245n8.4
si:ch211-245n8.4
chr8_-_50525360 0.09 ENSDART00000175648
CABZ01060030.1

chr5_+_60590796 0.09 ENSDART00000159859
tmem132e
transmembrane protein 132E
chr9_-_37613792 0.09 ENSDART00000138345
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr2_-_22152797 0.08 ENSDART00000145188
cyp7a1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr24_-_11908115 0.08 ENSDART00000184329
tm9sf1
transmembrane 9 superfamily member 1
chr15_-_18218227 0.08 ENSDART00000156332
btr21
bloodthirsty-related gene family, member 21
chr24_-_41267184 0.08 ENSDART00000063504
xylb
xylulokinase homolog (H. influenzae)
chr7_-_6432854 0.08 ENSDART00000172954
si:ch1073-153i20.4
si:ch1073-153i20.4
chr10_+_45128375 0.08 ENSDART00000164805
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr20_+_28266892 0.08 ENSDART00000103330
chac1
ChaC, cation transport regulator homolog 1 (E. coli)
chr11_+_12175162 0.08 ENSDART00000125446
si:ch211-156l18.7
si:ch211-156l18.7
chr17_+_45607580 0.08 ENSDART00000122583
si:ch211-202f3.4
si:ch211-202f3.4
chr10_+_40660772 0.07 ENSDART00000148007
taar19l
trace amine associated receptor 19l
chr3_-_59981162 0.07 ENSDART00000128790
cdr2l
cerebellar degeneration-related protein 2-like
chr9_-_32837860 0.07 ENSDART00000142227
mxe
myxovirus (influenza virus) resistance E
chr10_-_32660716 0.07 ENSDART00000063544
ENSDART00000141013
atg101
autophagy related 101
chr8_+_26859639 0.07 ENSDART00000133440
prdm2a
PR domain containing 2, with ZNF domain a
chr14_-_8724290 0.07 ENSDART00000161171
pimr56
Pim proto-oncogene, serine/threonine kinase, related 56
chr19_-_38830582 0.07 ENSDART00000189966
ENSDART00000183055
adgrb2
adhesion G protein-coupled receptor B2
chr20_-_1239596 0.07 ENSDART00000049063
ENSDART00000140650
ankrd6b
ankyrin repeat domain 6b
chr6_-_55354004 0.06 ENSDART00000165911
pcif1
PDX1 C-terminal inhibiting factor 1
chr14_-_38827442 0.06 ENSDART00000160000
spdl1
spindle apparatus coiled-coil protein 1
chr16_+_25137483 0.06 ENSDART00000155666
znf576.1
zinc finger protein 576, tandem duplicate 1
chr16_-_41131578 0.06 ENSDART00000102649
ENSDART00000145956
ptpn23a
protein tyrosine phosphatase, non-receptor type 23, a
chr3_-_26184018 0.05 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr12_+_46462090 0.05 ENSDART00000130748
BX005305.2

chr22_-_817479 0.05 ENSDART00000123487
zgc:153675
zgc:153675
chr4_-_30422325 0.04 ENSDART00000158444
znf1114
zinc finger protein 1114
chr8_-_2153147 0.04 ENSDART00000124093
si:dkeyp-117b11.1
si:dkeyp-117b11.1
chr5_-_42894068 0.04 ENSDART00000169606
cxcl11.1
chemokine (C-X-C motif) ligand 11, duplicate 1
chr11_+_42587900 0.04 ENSDART00000167529
asb14a
ankyrin repeat and SOCS box containing 14a
chr17_-_6076084 0.04 ENSDART00000058890
ephx2
epoxide hydrolase 2, cytoplasmic
chr7_-_45990386 0.04 ENSDART00000186008
si:ch211-260e23.7
si:ch211-260e23.7
chr17_+_3128273 0.03 ENSDART00000122453
zgc:136872
zgc:136872
chr4_+_34369818 0.03 ENSDART00000160548
si:ch211-246b8.1
si:ch211-246b8.1
chr15_-_23485752 0.03 ENSDART00000152706
nlrx1
NLR family member X1
chr8_+_4838114 0.03 ENSDART00000146667
es1
es1 protein
chr15_-_19677511 0.03 ENSDART00000043743
si:dkey-4p15.3
si:dkey-4p15.3
chr7_-_29223614 0.03 ENSDART00000173598
herc1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr18_+_7204378 0.02 ENSDART00000142905
vwf
von Willebrand factor
chr17_-_21993620 0.02 ENSDART00000179905
ENSDART00000078873
slc22a7b.3
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 3
chr14_-_6943934 0.02 ENSDART00000126279
clk4a
CDC-like kinase 4a
chr21_-_22474362 0.02 ENSDART00000169659
myo5b
myosin VB
chr25_-_20574859 0.02 ENSDART00000067288
adal
adenosine deaminase-like
chr11_-_17755444 0.02 ENSDART00000154627
eogt
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr12_+_46512881 0.02 ENSDART00000105454
CU855711.1

chr3_+_5297493 0.01 ENSDART00000138596
si:ch211-150d5.3
si:ch211-150d5.3
chr21_-_8054977 0.01 ENSDART00000130508
si:dkey-163m14.4
si:dkey-163m14.4
chr1_+_260039 0.01 ENSDART00000092584
ENSDART00000111806
cenpe
centromere protein E
chr5_+_67371650 0.01 ENSDART00000142156
sebox
SEBOX homeobox
chr22_-_8455462 0.01 ENSDART00000185238
CABZ01061508.1

chr16_+_33902006 0.00 ENSDART00000161807
ENSDART00000159474
gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr1_+_594736 0.00 ENSDART00000166731
jam2a
junctional adhesion molecule 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of tcf7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.2 0.5 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.4 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.1 1.0 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.3 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.1 1.0 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.4 GO:0003173 ventriculo bulbo valve development(GO:0003173) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.4 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.1 0.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.3 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.3 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.3 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.3 GO:0001839 neural plate morphogenesis(GO:0001839)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607) nuclear pore organization(GO:0006999)
0.0 0.4 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.2 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0097384 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.8 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.8 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.8 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.3 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.7 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.6 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0008206 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.0 0.4 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.3 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.4 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.7 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.9 GO:0030496 midbody(GO:0030496)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.2 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.1 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.8 GO:0016530 metallochaperone activity(GO:0016530)
0.1 1.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.3 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.3 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.8 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.0 0.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis