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PRJNA195909:zebrafish embryo and larva development

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Results for tfap4

Z-value: 2.19

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Transcription factors associated with tfap4

Gene Symbol Gene ID Gene Info
tfap4
ENSDARG00000103923 transcription factor AP-4 (activating enhancer binding protein 4)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tfap4dr11_v1_chr3_-_12227359_12227359-0.186.4e-01Click!

Activity profile of tfap4 motif

Sorted Z-values of tfap4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_20693743 5.79 ENSDART00000153023
ENSDART00000153370
st6galnac1.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr7_+_17947217 5.49 ENSDART00000101601
cth1
cysteine three histidine 1
chr9_-_5351017 4.74 ENSDART00000082260
abhd13
abhydrolase domain containing 13
chr15_+_38299563 4.30 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr11_+_45448212 4.06 ENSDART00000173341
sos1
son of sevenless homolog 1 (Drosophila)
chr4_-_17278904 3.60 ENSDART00000178686
ENSDART00000135730
lrmp
lymphoid-restricted membrane protein
chr15_+_38308421 3.04 ENSDART00000129941
si:dkey-24p1.6
si:dkey-24p1.6
chr13_-_2336584 2.93 ENSDART00000113692
tceb3l
transcription elongation factor B (SIII), polypeptide 3, like
chr14_-_34605607 2.66 ENSDART00000191608
afap1l1a
actin filament associated protein 1-like 1a
chr5_-_9216758 2.57 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr12_-_10505986 2.57 ENSDART00000152672
zgc:152977
zgc:152977
chr10_+_399363 2.52 ENSDART00000147449
si:ch211-242f23.8
si:ch211-242f23.8
chr14_-_34605804 2.46 ENSDART00000144547
afap1l1a
actin filament associated protein 1-like 1a
chr12_+_4920451 2.38 ENSDART00000171525
ENSDART00000159986
plekhm1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr10_-_25217347 2.36 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr14_+_35464994 2.35 ENSDART00000115307
si:ch211-203d1.3
si:ch211-203d1.3
chr17_-_17759138 2.31 ENSDART00000157128
ENSDART00000123845
adck1
aarF domain containing kinase 1
chr21_-_32060993 2.17 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr17_+_43868441 2.09 ENSDART00000134272
zgc:66313
zgc:66313
chr17_-_38887424 2.07 ENSDART00000141177
slc24a4a
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4a
chr5_+_37903790 2.07 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr12_-_33359654 1.99 ENSDART00000001907
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr2_-_55779927 1.99 ENSDART00000168579
CABZ01066725.1

chr19_+_10661520 1.97 ENSDART00000091813
ENSDART00000165653
ago3b
argonaute RISC catalytic component 3b
chr16_-_21489514 1.94 ENSDART00000149525
ENSDART00000148517
ENSDART00000146914
ENSDART00000186493
ENSDART00000193081
ENSDART00000186017
mpp6a
membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)
chr5_+_65970235 1.94 ENSDART00000166432
slc2a8
solute carrier family 2 (facilitated glucose transporter), member 8
chr10_+_31809226 1.93 ENSDART00000087898
foxo1b
forkhead box O1 b
chr14_+_50918769 1.92 ENSDART00000146918
rnf44
ring finger protein 44
chr13_+_40815012 1.91 ENSDART00000016960
prkg1a
protein kinase, cGMP-dependent, type Ia
chr21_+_4204860 1.91 ENSDART00000146541
rapgef1b
Rap guanine nucleotide exchange factor (GEF) 1b
chr7_+_73308566 1.90 ENSDART00000187039
ENSDART00000174244
CABZ01081777.1

chr9_-_1200187 1.90 ENSDART00000158760
ino80da
INO80 complex subunit Da
chr23_-_18057851 1.90 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
zgc:92287
chr16_-_24642814 1.88 ENSDART00000153987
ENSDART00000154319
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr19_+_14454306 1.86 ENSDART00000161965
zdhhc18b
zinc finger, DHHC-type containing 18b
chr3_+_14571813 1.86 ENSDART00000146728
ENSDART00000171731
znf653
zinc finger protein 653
chr17_+_14965570 1.84 ENSDART00000066604
gpr137c
G protein-coupled receptor 137c
chr9_+_38168012 1.84 ENSDART00000102445
clasp1a
cytoplasmic linker associated protein 1a
chr2_+_37245382 1.82 ENSDART00000004626
sec62
SEC62 homolog, preprotein translocation factor
chr7_-_69795488 1.81 ENSDART00000162414
USP53 (1 of many)
ubiquitin specific peptidase 53
chr9_-_27717006 1.81 ENSDART00000146860
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr6_-_9952103 1.81 ENSDART00000065475
zp2l2
zona pellucida glycoprotein 2, like 2
chr6_+_45494227 1.79 ENSDART00000159863
cntn4
contactin 4
chr8_-_22326073 1.79 ENSDART00000084965
cep104
centrosomal protein 104
chr5_-_11809404 1.79 ENSDART00000132564
nf2a
neurofibromin 2a (merlin)
chr5_-_68333081 1.78 ENSDART00000168786
h1m
linker histone H1M
chr21_-_3606539 1.77 ENSDART00000062418
dym
dymeclin
chr2_+_24700922 1.75 ENSDART00000170467
pik3r2
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr2_+_44518636 1.75 ENSDART00000153733
pask
PAS domain containing serine/threonine kinase
chr5_+_31779911 1.74 ENSDART00000098163
slc25a25b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr18_-_399554 1.73 ENSDART00000164374
ENSDART00000186311
ENSDART00000181816
ENSDART00000181892
si:ch211-79l17.1
si:ch211-79l17.1
chr8_+_48966165 1.73 ENSDART00000165425
aak1a
AP2 associated kinase 1a
chr14_+_16083818 1.72 ENSDART00000168462
rnf103
ring finger protein 103
chr8_+_48965767 1.72 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr16_+_41067586 1.71 ENSDART00000181876
scap
SREBF chaperone
chr12_-_3840664 1.67 ENSDART00000160967
taok2b
TAO kinase 2b
chr13_+_28580357 1.66 ENSDART00000007211
wbp1la
WW domain binding protein 1-like a
chr15_-_5624361 1.66 ENSDART00000176446
ENSDART00000114410
wdr62
WD repeat domain 62
chr19_-_2085027 1.66 ENSDART00000063615
snx13
sorting nexin 13
chr5_-_29195063 1.65 ENSDART00000109926
man1b1b
mannosidase, alpha, class 1B, member 1b
chr21_-_21515466 1.65 ENSDART00000147593
nectin3b
nectin cell adhesion molecule 3b
chr21_+_76739 1.65 ENSDART00000174654
ARSB
arylsulfatase B
chr6_-_8360918 1.64 ENSDART00000004716
acp5a
acid phosphatase 5a, tartrate resistant
chr16_-_30655980 1.64 ENSDART00000146508
ldlrad4b
low density lipoprotein receptor class A domain containing 4b
chr11_-_11792766 1.63 ENSDART00000011657
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr15_-_31147301 1.62 ENSDART00000157145
ENSDART00000155473
ENSDART00000048103
ksr1b
kinase suppressor of ras 1b
chr3_-_40836081 1.62 ENSDART00000143135
wipi2
WD repeat domain, phosphoinositide interacting 2
chr5_-_65121747 1.61 ENSDART00000165556
tor2a
torsin family 2, member A
chr23_-_3511630 1.59 ENSDART00000019667
rnf114
ring finger protein 114
chr2_-_17114852 1.58 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr22_-_16443199 1.58 ENSDART00000006290
ENSDART00000193335
plekhb2
pleckstrin homology domain containing, family B (evectins) member 2
chr19_-_4793263 1.57 ENSDART00000147510
ENSDART00000141336
ENSDART00000110551
ENSDART00000146684
st3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr5_-_32336613 1.56 ENSDART00000139732
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr15_-_16177603 1.56 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr23_+_25893020 1.56 ENSDART00000144769
pkig
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr16_-_42750295 1.56 ENSDART00000176570
slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr9_-_39624173 1.55 ENSDART00000180106
ENSDART00000126766
erbb4b
erb-b2 receptor tyrosine kinase 4b
chr9_+_46745348 1.55 ENSDART00000025256
igfbp2b
insulin-like growth factor binding protein 2b
chr7_-_59515569 1.55 ENSDART00000163343
ENSDART00000165457
ENSDART00000163745
slx1b
SLX1 homolog B, structure-specific endonuclease subunit
chr13_-_17464362 1.55 ENSDART00000145499
lrmda
leucine rich melanocyte differentiation associated
chr22_-_3299100 1.54 ENSDART00000160305
si:zfos-943e10.1
si:zfos-943e10.1
chr16_-_22544047 1.53 ENSDART00000131657
cgna
cingulin a
chr17_-_41798856 1.51 ENSDART00000156031
ENSDART00000192801
ENSDART00000180172
ENSDART00000084745
ENSDART00000175577
ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr3_+_7771420 1.51 ENSDART00000156809
ENSDART00000156309
hook2
hook microtubule-tethering protein 2
chr23_-_19831739 1.51 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr20_-_35508805 1.49 ENSDART00000169538
adgrf3b
adhesion G protein-coupled receptor F3b
chr20_+_20731052 1.48 ENSDART00000047662
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr3_-_21118969 1.48 ENSDART00000129016
maza
MYC-associated zinc finger protein a (purine-binding transcription factor)
chr9_+_21306902 1.48 ENSDART00000138554
ENSDART00000004108
xpo4
exportin 4
chr1_+_35473219 1.47 ENSDART00000109678
ENSDART00000181635
usp38
ubiquitin specific peptidase 38
chr6_+_59991076 1.47 ENSDART00000163575
CABZ01100888.1

chr7_+_34794829 1.44 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
esrp2
epithelial splicing regulatory protein 2
chr8_+_25145464 1.44 ENSDART00000136505
gnai3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr10_+_15340768 1.43 ENSDART00000046274
ENSDART00000168909
trappc13
trafficking protein particle complex 13
chr16_-_4610255 1.43 ENSDART00000081852
ENSDART00000123253
ENSDART00000127554
ENSDART00000029485
arnt
aryl hydrocarbon receptor nuclear translocator
chr20_-_40367493 1.43 ENSDART00000075096
smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
chr9_+_33154841 1.42 ENSDART00000132465
dopey2
dopey family member 2
chr8_-_4010887 1.41 ENSDART00000163678
mtmr3
myotubularin related protein 3
chr13_+_16521898 1.40 ENSDART00000122557
kcnma1a
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr10_-_10969596 1.39 ENSDART00000092011
exd3
exonuclease 3'-5' domain containing 3
chr11_-_44999858 1.39 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr19_-_20446756 1.38 ENSDART00000140711
tbc1d5
TBC1 domain family, member 5
chr1_+_35473397 1.38 ENSDART00000158799
usp38
ubiquitin specific peptidase 38
chr12_-_33579873 1.38 ENSDART00000184661
tdrkh
tudor and KH domain containing
chr2_-_20866758 1.37 ENSDART00000165374
tpra
translocated promoter region a, nuclear basket protein
chr15_-_9421481 1.37 ENSDART00000189045
ENSDART00000177158
sacs
sacsin molecular chaperone
chr5_-_16405651 1.36 ENSDART00000163942
slc39a14
solute carrier family 39 (zinc transporter), member 14
chr10_-_10969444 1.35 ENSDART00000138041
exd3
exonuclease 3'-5' domain containing 3
chr1_+_41666611 1.35 ENSDART00000145789
fbxo41
F-box protein 41
chr24_+_5811808 1.34 ENSDART00000132428
si:ch211-157j23.3
si:ch211-157j23.3
chr5_-_11809710 1.34 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
nf2a
neurofibromin 2a (merlin)
chr8_+_23382568 1.33 ENSDART00000129167
mapre1a
microtubule-associated protein, RP/EB family, member 1a
chr2_+_20866898 1.33 ENSDART00000150086
odr4
odr-4 GPCR localization factor homolog
chr10_-_35257458 1.33 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr23_-_18057270 1.32 ENSDART00000173385
zgc:92287
zgc:92287
chr10_-_11840353 1.31 ENSDART00000127581
trim23
tripartite motif containing 23
chr10_+_1849874 1.31 ENSDART00000158897
ENSDART00000149956
apc
adenomatous polyposis coli
chr13_-_17464654 1.31 ENSDART00000140312
lrmda
leucine rich melanocyte differentiation associated
chr4_+_5832311 1.30 ENSDART00000121743
ENSDART00000158233
ENSDART00000165187
si:ch73-352p4.5
si:ch73-352p4.5
chr12_+_33894396 1.29 ENSDART00000130853
ENSDART00000152988
mfsd13a
major facilitator superfamily domain containing 13A
chr14_-_16754262 1.28 ENSDART00000001159
mgat4b
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr2_-_17115256 1.27 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr3_-_34753605 1.26 ENSDART00000000160
thraa
thyroid hormone receptor alpha a
chr12_+_31638045 1.25 ENSDART00000184216
ENSDART00000183645
ENSDART00000153129
dnmbp
dynamin binding protein
chr13_-_33114933 1.25 ENSDART00000140543
ENSDART00000075953
zfyve26
zinc finger, FYVE domain containing 26
chr11_+_24314148 1.24 ENSDART00000171491
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr9_+_21795917 1.24 ENSDART00000169069
rev1
REV1, polymerase (DNA directed)
chr23_+_27778670 1.23 ENSDART00000053863
kmt2d
lysine (K)-specific methyltransferase 2D
chr23_+_44461493 1.23 ENSDART00000149854
si:ch1073-228j22.1
si:ch1073-228j22.1
chr5_-_37341044 1.23 ENSDART00000084675
wdr44
WD repeat domain 44
chr23_-_18057553 1.22 ENSDART00000173102
ENSDART00000058742
zgc:92287
zgc:92287
chr12_+_10116912 1.22 ENSDART00000189630
si:dkeyp-118b1.2
si:dkeyp-118b1.2
chr5_-_2636078 1.21 ENSDART00000122274
cita
citron rho-interacting serine/threonine kinase a
chr17_+_51940768 1.21 ENSDART00000053422
ttll5
tubulin tyrosine ligase-like family, member 5
chr3_-_33113879 1.20 ENSDART00000044677
rarab
retinoic acid receptor, alpha b
chr17_-_18898115 1.20 ENSDART00000028044
galcb
galactosylceramidase b
chr3_+_41731527 1.20 ENSDART00000049007
ENSDART00000187866
chst12a
carbohydrate (chondroitin 4) sulfotransferase 12a
chr23_-_21748805 1.20 ENSDART00000148128
vps13d
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr6_+_33076839 1.19 ENSDART00000073755
ENSDART00000122242
pomgnt1
protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
chr8_-_14609284 1.19 ENSDART00000146175
cep350
centrosomal protein 350
chr24_-_27256338 1.19 ENSDART00000105768
zmynd11
zinc finger, MYND-type containing 11
chr16_-_36196700 1.18 ENSDART00000172324
capn7
calpain 7
chr16_-_54971277 1.18 ENSDART00000113358
wdtc1
WD and tetratricopeptide repeats 1
chr2_-_11027258 1.18 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
ssbp3a
single stranded DNA binding protein 3a
chr19_+_43684376 1.18 ENSDART00000051723
si:ch211-193k19.1
si:ch211-193k19.1
chr19_-_42503143 1.18 ENSDART00000007642
zgc:110239
zgc:110239
chr16_-_21903083 1.16 ENSDART00000165849
setdb1b
SET domain, bifurcated 1b
chr12_-_25150239 1.16 ENSDART00000038415
ENSDART00000135368
rhoq
ras homolog family member Q
chr24_+_5811350 1.16 ENSDART00000178238
si:ch211-157j23.3
si:ch211-157j23.3
chr9_+_2522797 1.16 ENSDART00000186786
ENSDART00000147034
gpr155a
G protein-coupled receptor 155a
chr15_-_30857350 1.16 ENSDART00000138988
akap1b
A kinase (PRKA) anchor protein 1b
chr18_-_7948188 1.15 ENSDART00000091805
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr2_-_22286828 1.15 ENSDART00000168653
fam110b
family with sequence similarity 110, member B
chr20_-_28361574 1.15 ENSDART00000103352
vps18
vacuolar protein sorting 18 homolog (S. cerevisiae)
chr10_+_44373349 1.14 ENSDART00000172191
snrnp35
small nuclear ribonucleoprotein 35 (U11/U12)
chr1_-_14258409 1.14 ENSDART00000079359
pde5aa
phosphodiesterase 5A, cGMP-specific, a
chr8_-_410199 1.13 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
trim36
tripartite motif containing 36
chr5_-_24245218 1.13 ENSDART00000042481
phf23a
PHD finger protein 23a
chr11_-_3533356 1.13 ENSDART00000161972
ddx19
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)
chr6_-_7776612 1.11 ENSDART00000190269
myh9a
myosin, heavy chain 9a, non-muscle
chr24_+_35183595 1.11 ENSDART00000075142
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr18_-_42071876 1.11 ENSDART00000193288
ENSDART00000189021
ENSDART00000019245
arhgap42b
Rho GTPase activating protein 42b
chr19_-_10214264 1.10 ENSDART00000053300
ENSDART00000148225
znf865
zinc finger protein 865
chr18_-_41232297 1.10 ENSDART00000036928
fbxo36a
F-box protein 36a
chr19_+_15509372 1.10 ENSDART00000151530
pdik1l
PDLIM1 interacting kinase 1 like
chr15_+_24676905 1.09 ENSDART00000078014
ENSDART00000143137
poldip2
polymerase (DNA-directed), delta interacting protein 2
chr16_+_27383717 1.09 ENSDART00000132329
ENSDART00000136256
stx17
syntaxin 17
chr2_-_37098785 1.09 ENSDART00000003670
zgc:101744
zgc:101744
chr5_+_30392148 1.09 ENSDART00000086765
stk36
serine/threonine kinase 36 (fused homolog, Drosophila)
chr19_+_4968947 1.09 ENSDART00000003634
ENSDART00000134808
stard3
StAR-related lipid transfer (START) domain containing 3
chr16_+_23796612 1.08 ENSDART00000131698
rab13
RAB13, member RAS oncogene family
chr18_+_6641542 1.07 ENSDART00000160379
c2cd5
C2 calcium-dependent domain containing 5
chr9_+_2020667 1.07 ENSDART00000157818
lnpa
limb and neural patterns a
chr18_-_19819812 1.07 ENSDART00000060344
aagab
alpha and gamma adaptin binding protein
chr18_+_45526585 1.07 ENSDART00000138511
kifc3
kinesin family member C3
chr15_+_40188076 1.06 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr10_+_37182626 1.05 ENSDART00000137636
ksr1a
kinase suppressor of ras 1a
chr17_-_8570257 1.05 ENSDART00000154713
ENSDART00000121488
fzd3b
frizzled class receptor 3b
chr24_+_14937205 1.05 ENSDART00000091735
dok6
docking protein 6
chr2_+_25560556 1.05 ENSDART00000133623
pld1a
phospholipase D1a
chr23_+_13528550 1.05 ENSDART00000099903
uckl1b
uridine-cytidine kinase 1-like 1b
chr6_+_18520859 1.05 ENSDART00000158263
si:dkey-10p5.10
si:dkey-10p5.10
chr23_-_21758253 1.05 ENSDART00000046613
vps13d
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr7_+_66634167 1.05 ENSDART00000027616
eif4g2a
eukaryotic translation initiation factor 4, gamma 2a
chr24_+_18689980 1.04 ENSDART00000160941
ENSDART00000180303
ENSDART00000190435
cspp1a
centrosome and spindle pole associated protein 1a
chr9_+_50110763 1.04 ENSDART00000162990
cobll1b
cordon-bleu WH2 repeat protein-like 1b
chr15_+_47746176 1.03 ENSDART00000154481
ENSDART00000160914
stard10
StAR-related lipid transfer (START) domain containing 10
chr24_-_31123365 1.03 ENSDART00000182947
tmem56a
transmembrane protein 56a
chr24_-_27256673 1.03 ENSDART00000181182
zmynd11
zinc finger, MYND-type containing 11
chr20_+_43691208 1.02 ENSDART00000152976
ENSDART00000045185
lin9
lin-9 DREAM MuvB core complex component
chr19_-_15192840 1.00 ENSDART00000151337
phactr4a
phosphatase and actin regulator 4a
chr1_+_57348756 1.00 ENSDART00000063750
b3gntl1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr7_+_41265618 1.00 ENSDART00000173688
scrib
scribbled planar cell polarity protein
chr6_-_54348568 1.00 ENSDART00000156501
zgc:101577
zgc:101577
chr20_+_715739 1.00 ENSDART00000136768
myo6a
myosin VIa
chr17_+_24446705 1.00 ENSDART00000163221
ugp2b
UDP-glucose pyrophosphorylase 2b
chr1_+_35956435 0.98 ENSDART00000085021
ENSDART00000148505
mmaa
methylmalonic aciduria (cobalamin deficiency) cblA type
chr19_-_23249822 0.98 ENSDART00000140665
grb10a
growth factor receptor-bound protein 10a
chr2_-_31800521 0.98 ENSDART00000112763
retreg1
reticulophagy regulator 1
chr1_-_50293946 0.98 ENSDART00000053028
ENSDART00000125099
tbck
TBC1 domain containing kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of tfap4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0035046 pronuclear migration(GO:0035046)
0.6 1.8 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.6 1.8 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.6 2.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.6 1.7 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.5 2.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.5 1.4 GO:0033212 iron assimilation(GO:0033212)
0.4 2.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 1.6 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.4 2.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.3 1.3 GO:0090244 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.3 1.0 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.3 1.0 GO:0070126 mitochondrial translational termination(GO:0070126)
0.3 1.6 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.3 0.9 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.3 1.2 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.3 1.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.3 1.9 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 1.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.3 1.1 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.3 1.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.3 1.8 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 1.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 2.0 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 0.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 1.0 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 2.9 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 0.7 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 1.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2 1.2 GO:0043476 pigment accumulation(GO:0043476)
0.2 1.1 GO:0061439 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.2 1.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.2 2.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.8 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 1.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 3.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 0.8 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.2 2.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 1.4 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.2 1.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.2 0.6 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 1.6 GO:0045453 bone resorption(GO:0045453)
0.2 0.7 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.2 1.8 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.2 0.9 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.2 1.2 GO:0016266 O-glycan processing(GO:0016266)
0.2 0.8 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.2 2.0 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.2 0.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.2 1.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 1.8 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.2 0.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 0.8 GO:0043111 replication fork arrest(GO:0043111)
0.2 0.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 0.8 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.2 1.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 1.9 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.6 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 1.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.2 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 1.5 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.7 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 1.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.8 GO:0044783 G1 DNA damage checkpoint(GO:0044783)
0.1 0.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 1.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.8 GO:1902946 protein localization to early endosome(GO:1902946)
0.1 0.6 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.1 1.0 GO:0061709 reticulophagy(GO:0061709)
0.1 0.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 0.8 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.6 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 1.7 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 1.0 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 1.0 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.9 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.8 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.8 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.8 GO:1990402 embryonic liver development(GO:1990402)
0.1 0.9 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.4 GO:1900136 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 1.0 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 0.8 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 1.2 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.9 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 1.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 1.0 GO:0003139 secondary heart field specification(GO:0003139)
0.1 1.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 2.6 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.6 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.4 GO:0033151 V(D)J recombination(GO:0033151)
0.1 0.6 GO:0007020 microtubule nucleation(GO:0007020)
0.1 1.7 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.5 GO:0090329 regulation of DNA-dependent DNA replication(GO:0090329)
0.1 0.2 GO:1903646 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.1 0.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 2.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.0 GO:0032094 response to food(GO:0032094)
0.1 1.8 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.1 1.6 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 2.3 GO:0060972 left/right pattern formation(GO:0060972)
0.1 0.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 1.2 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.9 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 1.7 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 0.6 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.7 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 1.9 GO:0051225 spindle assembly(GO:0051225)
0.1 1.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 1.0 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 1.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.8 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.9 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.0 2.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.7 GO:0030259 lipid glycosylation(GO:0030259)
0.0 2.2 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.5 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 1.4 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.3 GO:0032387 negative regulation of intracellular transport(GO:0032387)
0.0 0.2 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.2 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 0.1 GO:0015824 L-alanine transport(GO:0015808) proline transport(GO:0015824)
0.0 0.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 2.8 GO:0055088 lipid homeostasis(GO:0055088)
0.0 1.3 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.9 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 2.0 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 2.4 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.6 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 2.7 GO:0007030 Golgi organization(GO:0007030)
0.0 1.1 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.7 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.0 0.4 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.3 GO:0001845 phagolysosome assembly(GO:0001845)
0.0 2.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.5 GO:0030901 midbrain development(GO:0030901)
0.0 0.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 8.4 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.3 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 1.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 3.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0008272 sulfate transport(GO:0008272)
0.0 0.7 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.0 2.3 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 3.9 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.1 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.8 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.7 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.0 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0015810 C4-dicarboxylate transport(GO:0015740) acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:1902803 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.9 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.9 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 1.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.6 GO:0007259 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 3.6 GO:0006897 endocytosis(GO:0006897)
0.0 1.1 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.7 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0097352 autophagosome maturation(GO:0097352)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.5 1.4 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.4 5.1 GO:0002102 podosome(GO:0002102)
0.4 1.8 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.4 1.1 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.3 1.4 GO:0097519 DNA recombinase complex(GO:0097519)
0.3 3.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 0.8 GO:1990745 EARP complex(GO:1990745)
0.3 1.5 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.2 2.0 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 0.7 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.2 0.9 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 0.8 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 0.9 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 0.5 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2 1.5 GO:0070652 HAUS complex(GO:0070652)
0.2 0.8 GO:0071203 WASH complex(GO:0071203)
0.2 1.2 GO:0030897 HOPS complex(GO:0030897)
0.2 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 0.8 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 1.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 2.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.7 GO:0032797 SMN complex(GO:0032797)
0.1 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.2 GO:0072380 TRC complex(GO:0072380)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.3 GO:0071439 clathrin complex(GO:0071439)
0.1 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 6.8 GO:0000786 nucleosome(GO:0000786)
0.1 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 2.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.1 1.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 2.9 GO:0005643 nuclear pore(GO:0005643)
0.1 0.9 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.8 GO:0044545 NSL complex(GO:0044545)
0.0 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 2.0 GO:0005657 replication fork(GO:0005657)
0.0 3.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 1.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 3.1 GO:0000922 spindle pole(GO:0000922)
0.0 0.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.4 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 1.8 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 3.2 GO:0005795 Golgi stack(GO:0005795)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 2.3 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 1.2 GO:0030496 midbody(GO:0030496)
0.0 1.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.5 GO:0030027 lamellipodium(GO:0030027)
0.0 3.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 1.8 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.9 GO:0030141 secretory granule(GO:0030141)
0.0 2.8 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 15.2 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 1.4 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.7 GO:0005813 centrosome(GO:0005813)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 2.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.6 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 2.1 GO:0043296 apical junction complex(GO:0043296)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0 0.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.4 GO:0005764 lysosome(GO:0005764)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.5 2.5 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.5 1.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.4 1.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 1.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 1.4 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.3 1.6 GO:0070412 R-SMAD binding(GO:0070412)
0.3 1.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.3 1.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.3 3.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 1.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 1.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 0.9 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 2.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 4.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 0.9 GO:0008169 C-methyltransferase activity(GO:0008169)
0.2 0.9 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 2.6 GO:0043495 protein anchor(GO:0043495)
0.2 1.5 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 1.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 1.8 GO:0043515 kinetochore binding(GO:0043515)
0.2 2.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 1.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 1.4 GO:0030274 LIM domain binding(GO:0030274)
0.2 2.0 GO:0035198 miRNA binding(GO:0035198)
0.2 1.0 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.7 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.2 0.7 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 1.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 0.7 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.2 1.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.2 0.9 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2 1.1 GO:0004630 phospholipase D activity(GO:0004630)
0.2 5.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 2.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 1.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.5 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 2.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.5 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 0.4 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 1.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.5 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.7 GO:0048156 tau protein binding(GO:0048156)
0.1 1.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 1.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 6.1 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.4 GO:0070513 death domain binding(GO:0070513)
0.1 1.9 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.7 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.0 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.9 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.9 GO:0030332 cyclin binding(GO:0030332)
0.1 1.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.2 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.6 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 1.5 GO:0002039 p53 binding(GO:0002039)
0.1 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.1 2.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.5 GO:0015923 mannosidase activity(GO:0015923)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 4.2 GO:0032934 sterol binding(GO:0032934)
0.1 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.9 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.5 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.5 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 1.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 2.4 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.3 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 2.7 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 1.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 3.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 2.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 4.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.9 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.7 GO:0048038 quinone binding(GO:0048038)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.1 GO:0017069 snRNA binding(GO:0017069)
0.0 1.3 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.7 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.6 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 2.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 0.8 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 1.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.7 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 5.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.8 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.5 GO:0030276 clathrin binding(GO:0030276)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.7 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 1.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.2 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.9 GO:0060090 binding, bridging(GO:0060090)
0.0 1.9 GO:0004713 protein tyrosine kinase activity(GO:0004713)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.4 PID ATR PATHWAY ATR signaling pathway
0.0 1.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.7 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.9 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.3 1.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 1.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 1.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 1.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 1.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 1.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 2.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.2 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis