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PRJNA195909:zebrafish embryo and larva development

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Results for vox

Z-value: 0.73

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Transcription factors associated with vox

Gene Symbol Gene ID Gene Info
vox
ENSDARG00000099761 ventral homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
voxdr11_v1_chr13_-_50624743_506247430.088.4e-01Click!

Activity profile of vox motif

Sorted Z-values of vox motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_48667056 1.70 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr4_+_5506952 1.32 ENSDART00000032857
ENSDART00000160222
mapk11
mitogen-activated protein kinase 11
chr10_+_32104305 1.24 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr23_+_35713557 1.23 ENSDART00000123518
tuba1c
tubulin, alpha 1c
chr23_+_20110086 1.13 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr21_+_6751405 1.11 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr21_+_6751760 1.10 ENSDART00000135914
olfm1b
olfactomedin 1b
chr16_-_7443388 1.08 ENSDART00000017445
prdm1a
PR domain containing 1a, with ZNF domain
chr6_-_7720332 1.07 ENSDART00000135945
rpsa
ribosomal protein SA
chr17_+_23298928 1.02 ENSDART00000153652
zgc:165461
zgc:165461
chr7_-_34262080 1.00 ENSDART00000183246
si:ch211-98n17.5
si:ch211-98n17.5
chr18_+_48423973 0.98 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr25_+_5035343 0.96 ENSDART00000011751
parvb
parvin, beta
chr15_-_15357178 0.95 ENSDART00000106120
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr5_-_14373662 0.89 ENSDART00000183694
tet3
tet methylcytosine dioxygenase 3
chr9_+_21402863 0.84 ENSDART00000125357
cx30.3
connexin 30.3
chr25_+_31868268 0.81 ENSDART00000022325
parp16
poly (ADP-ribose) polymerase family, member 16
chr8_+_17078692 0.80 ENSDART00000023206
plk2b
polo-like kinase 2b (Drosophila)
chr5_+_56268436 0.76 ENSDART00000021159
lhx1b
LIM homeobox 1b
chr1_+_52392511 0.75 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr6_-_54815886 0.74 ENSDART00000180793
ENSDART00000007498
tnni1b
troponin I type 1b (skeletal, slow)
chr25_-_18953322 0.71 ENSDART00000155927
si:ch211-68a17.7
si:ch211-68a17.7
chr6_-_39275793 0.71 ENSDART00000180477
ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr4_+_35553514 0.68 ENSDART00000182938
CR847906.1

chr3_-_15999501 0.68 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr10_-_40968095 0.67 ENSDART00000184104
npffr1l1
neuropeptide FF receptor 1 like 1
chr17_+_41992054 0.67 ENSDART00000182878
ENSDART00000111537
kiz
kizuna centrosomal protein
chr4_-_7212875 0.67 ENSDART00000161297
lrrn3b
leucine rich repeat neuronal 3b
chr1_+_34696503 0.66 ENSDART00000186106
CR339054.2

chr25_+_19149241 0.64 ENSDART00000184982
ENSDART00000067324
mfge8b
milk fat globule-EGF factor 8 protein b
chr20_+_26966725 0.62 ENSDART00000029781
ahsa1a
AHA1, activator of heat shock protein ATPase homolog 1a
chr12_-_314899 0.62 ENSDART00000066579
pts
6-pyruvoyltetrahydropterin synthase
chr24_+_38301080 0.61 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr21_-_17296789 0.60 ENSDART00000192180
gfi1b
growth factor independent 1B transcription repressor
chr5_+_29671681 0.60 ENSDART00000043096
ak8
adenylate kinase 8
chr5_-_64883082 0.60 ENSDART00000064983
ENSDART00000139066
krt1-c5
keratin, type 1, gene c5
chr3_-_53722182 0.59 ENSDART00000032788
rdh8a
retinol dehydrogenase 8a
chr20_-_43771871 0.58 ENSDART00000153304
matn3a
matrilin 3a
chr16_+_14707960 0.56 ENSDART00000137912
col14a1a
collagen, type XIV, alpha 1a
chr3_-_23643751 0.54 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr21_+_39948300 0.53 ENSDART00000137740
slc47a1
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr6_-_35401282 0.53 ENSDART00000127612
rgs5a
regulator of G protein signaling 5a
chr10_+_39091353 0.53 ENSDART00000125986
si:ch73-1a9.4
si:ch73-1a9.4
chr7_+_6652967 0.53 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr12_+_7445595 0.52 ENSDART00000103536
ENSDART00000152524
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr7_+_25033924 0.51 ENSDART00000170873
sb:cb1058
sb:cb1058
chr20_-_53435483 0.49 ENSDART00000135091
mettl24
methyltransferase like 24
chr2_-_10896745 0.48 ENSDART00000114609
cdcp2
CUB domain containing protein 2
chr11_+_30057762 0.46 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr1_+_27024068 0.46 ENSDART00000102322
bnc2
basonuclin 2
chr10_+_37137464 0.45 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr17_-_45525936 0.45 ENSDART00000084102
hhipl2
HHIP-like 2
chr15_+_5360407 0.45 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr19_+_26718074 0.43 ENSDART00000134455
zgc:100906
zgc:100906
chr24_+_6107901 0.42 ENSDART00000156419
si:ch211-37e10.2
si:ch211-37e10.2
chr5_-_51484156 0.41 ENSDART00000162064
CR388055.1

chr2_+_30787128 0.40 ENSDART00000189233
atp6v1h
ATPase H+ transporting V1 subunit H
chr1_+_27023687 0.40 ENSDART00000189093
bnc2
basonuclin 2
chr3_-_38783951 0.39 ENSDART00000155518
znf281a
zinc finger protein 281a
chr5_-_29671586 0.38 ENSDART00000098336
spaca9
sperm acrosome associated 9
chr2_+_30786773 0.38 ENSDART00000019029
ENSDART00000145681
atp6v1h
ATPase H+ transporting V1 subunit H
chr14_-_33105434 0.37 ENSDART00000163795
dlg3
discs, large homolog 3 (Drosophila)
chr11_+_38280454 0.37 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr6_+_42820228 0.37 ENSDART00000185413
sema3fa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr4_+_14727018 0.36 ENSDART00000124189
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr9_-_52962521 0.36 ENSDART00000170419
CU855885.1

chr3_-_15444396 0.34 ENSDART00000104361
si:dkey-56d12.4
si:dkey-56d12.4
chr8_-_50888806 0.34 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr20_-_14925281 0.33 ENSDART00000152641
dnm3a
dynamin 3a
chr5_+_66353750 0.32 ENSDART00000143410
si:ch211-261c8.5
si:ch211-261c8.5
chr20_-_47188966 0.28 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr4_+_57580303 0.28 ENSDART00000166492
ENSDART00000103025
ENSDART00000170786
il17ra1b
il17ra2
interleukin 17 receptor A1b
interleukin 17 receptor A2
chr11_-_29737088 0.27 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr19_+_7735157 0.27 ENSDART00000186717
tuft1b
tuftelin 1b
chr18_+_8346920 0.26 ENSDART00000083421
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr1_+_22691256 0.25 ENSDART00000017413
zmynd10
zinc finger, MYND-type containing 10
chr4_+_14727212 0.25 ENSDART00000158094
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr14_+_30568961 0.24 ENSDART00000184303
mrpl11
mitochondrial ribosomal protein L11
chr4_+_49322310 0.24 ENSDART00000184154
ENSDART00000167162
BX942819.1

chr6_+_15762647 0.24 ENSDART00000127133
ENSDART00000128939
iqca1
IQ motif containing with AAA domain 1
chr6_+_30091811 0.24 ENSDART00000088403
meltf
melanotransferrin
chr20_-_14924858 0.23 ENSDART00000047039
dnm3a
dynamin 3a
chr5_+_66353589 0.23 ENSDART00000138246
si:ch211-261c8.5
si:ch211-261c8.5
chr3_-_34084387 0.22 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr22_+_6905210 0.21 ENSDART00000167530
CABZ01065328.2

chr6_+_28051978 0.21 ENSDART00000143218
si:ch73-194h10.2
si:ch73-194h10.2
chr3_-_32337653 0.21 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr15_-_2497568 0.20 ENSDART00000080398
neu4
sialidase 4
chr21_-_32097908 0.20 ENSDART00000147387
si:ch211-160j14.3
si:ch211-160j14.3
chr11_+_2506516 0.19 ENSDART00000130886
ENSDART00000189767
NABP2
si:ch73-190f16.2
chr2_-_48171441 0.19 ENSDART00000123040
pfkpb
phosphofructokinase, platelet b
chr10_+_21867307 0.19 ENSDART00000126629
cbln17
cerebellin 17
chr15_-_2493771 0.19 ENSDART00000184906
neu4
sialidase 4
chr21_-_40317035 0.18 ENSDART00000143648
ENSDART00000013359
or101-1
odorant receptor, family B, subfamily 101, member 1
chr9_+_43799829 0.18 ENSDART00000186240
ube2e3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr23_-_7674902 0.16 ENSDART00000185612
ENSDART00000180524
plagl2
pleiomorphic adenoma gene-like 2
chr3_+_34919810 0.16 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr21_-_37790727 0.16 ENSDART00000162907
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr8_+_36942262 0.16 ENSDART00000188173
iqsec2b
IQ motif and Sec7 domain 2b
chr8_-_5220125 0.16 ENSDART00000035676
bnip3la
BCL2 interacting protein 3 like a
chr16_-_17197546 0.15 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr15_+_3790556 0.15 ENSDART00000181467
RNF14 (1 of many)
ring finger protein 14
chr1_-_17715493 0.15 ENSDART00000133027
si:dkey-256e7.8
si:dkey-256e7.8
chr4_-_67800414 0.14 ENSDART00000160213
si:ch211-66c13.1
si:ch211-66c13.1
chr19_-_10971230 0.14 ENSDART00000166196
LO018584.1

chr15_+_15856178 0.13 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr2_-_48171112 0.13 ENSDART00000156258
pfkpb
phosphofructokinase, platelet b
chr1_-_22691182 0.12 ENSDART00000076766
fgfbp2b
fibroblast growth factor binding protein 2b
chr22_-_36530902 0.11 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr15_-_38154616 0.11 ENSDART00000099392
irgq2
immunity-related GTPase family, q2
chr11_+_16152316 0.11 ENSDART00000081054
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr5_+_1589458 0.11 ENSDART00000167473
CABZ01076669.1

chr4_-_55459037 0.11 ENSDART00000172184
znf569l
zinc finger protein 569, like
chr12_-_7157527 0.11 ENSDART00000152274
si:dkey-187i8.2
si:dkey-187i8.2
chr21_+_21812311 0.10 ENSDART00000151253
neu3.4
sialidase 3 (membrane sialidase), tandem duplicate 4
chr14_+_30762131 0.10 ENSDART00000145039
si:ch211-145o7.3
si:ch211-145o7.3
chr11_+_24703108 0.10 ENSDART00000159173
gpr25
G protein-coupled receptor 25
chr23_+_41679586 0.09 ENSDART00000067662
CU914487.1

chr12_+_22580579 0.09 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr8_+_52637507 0.09 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr25_-_4148719 0.08 ENSDART00000112880
ENSDART00000023278
fads2
fatty acid desaturase 2
chr10_-_5847655 0.08 ENSDART00000192773
ankrd55
ankyrin repeat domain 55
chr11_-_16152400 0.07 ENSDART00000123665
arpc4l
actin related protein 2/3 complex, subunit 4, like
chr5_+_28160503 0.07 ENSDART00000051516
tacr1a
tachykinin receptor 1a
chr19_+_23932259 0.07 ENSDART00000139040
si:dkey-222b8.1
si:dkey-222b8.1
chr18_+_7286788 0.07 ENSDART00000022998
ANO2 (1 of many)
si:ch73-86n2.1
chr7_-_59210882 0.07 ENSDART00000170330
ENSDART00000158996
nagk
N-acetylglucosamine kinase
chr16_+_54209504 0.06 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr4_+_35594200 0.06 ENSDART00000193902
si:dkeyp-4c4.2
si:dkeyp-4c4.2
chr5_+_7989210 0.06 ENSDART00000168071
gdnfb
glial cell derived neurotrophic factor b
chr17_+_33311784 0.06 ENSDART00000156229
si:ch211-132f19.7
si:ch211-132f19.7
chr2_+_22363824 0.06 ENSDART00000163172
hs2st1a
heparan sulfate 2-O-sulfotransferase 1a
chr17_-_33289304 0.06 ENSDART00000135118
ENSDART00000040346
efr3ba
EFR3 homolog Ba (S. cerevisiae)
chr5_+_38752287 0.06 ENSDART00000133571
cxcl11.8
chemokine (C-X-C motif) ligand 11, duplicate 8
chr4_-_50930346 0.06 ENSDART00000184245
si:ch211-208f21.3
si:ch211-208f21.3
chr1_-_7582859 0.06 ENSDART00000110696
mxb
myxovirus (influenza) resistance B
chr2_+_33747509 0.06 ENSDART00000134187
si:dkey-31m5.5
si:dkey-31m5.5
chr10_+_3049636 0.05 ENSDART00000081794
ENSDART00000183167
ENSDART00000191634
ENSDART00000183514
rasgrf2a
Ras protein-specific guanine nucleotide-releasing factor 2a
chr2_-_23411368 0.05 ENSDART00000159495
si:ch73-129a22.11
si:ch73-129a22.11
chr4_-_49119557 0.05 ENSDART00000150263
znf1036
zinc finger protein 1036
chr19_-_7690975 0.05 ENSDART00000151384
si:dkey-204a24.10
si:dkey-204a24.10
chr8_-_25874426 0.05 ENSDART00000142730
opn7c
opsin 7, group member c
chr23_-_9991060 0.05 ENSDART00000111518
plxnb1a
plexin b1a
chr8_-_49764156 0.05 ENSDART00000177589
ENSDART00000189142
hnrnpk
heterogeneous nuclear ribonucleoprotein K
chr15_-_11955485 0.04 ENSDART00000160286
si:dkey-202l22.3
si:dkey-202l22.3
chr4_+_54645654 0.04 ENSDART00000192864
si:ch211-227e10.1
si:ch211-227e10.1
chr3_+_45365098 0.03 ENSDART00000052746
ENSDART00000156555
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr22_+_7738966 0.03 ENSDART00000147073
si:ch73-44m9.5
si:ch73-44m9.5
chr4_-_41269844 0.02 ENSDART00000186177
CR388165.2

chr21_+_40195452 0.02 ENSDART00000108650
or115-15
odorant receptor, family F, subfamily 115, member 15
chr2_-_22363460 0.02 ENSDART00000158486
selenof
selenoprotein F
chr19_+_10592778 0.02 ENSDART00000135488
ENSDART00000151624
si:dkey-211g8.5
si:dkey-211g8.5
chr19_+_46158078 0.01 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr7_+_66048102 0.01 ENSDART00000104523
arntl1b
aryl hydrocarbon receptor nuclear translocator-like 1b
chr20_+_45853154 0.01 ENSDART00000181109
AL929237.4

chr19_+_31541607 0.01 ENSDART00000181604
gmnn
geminin, DNA replication inhibitor
chr6_-_39344259 0.01 ENSDART00000104074
zgc:158846
zgc:158846
chr11_+_2391469 0.00 ENSDART00000182121
igfbp6a
insulin-like growth factor binding protein 6a
chr21_+_15713097 0.00 ENSDART00000015841
gstt1b
glutathione S-transferase theta 1b
chr9_-_12594759 0.00 ENSDART00000021266
tra2b
transformer 2 beta homolog

Network of associatons between targets according to the STRING database.

First level regulatory network of vox

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 0.9 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 0.7 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.8 GO:0048069 eye pigmentation(GO:0048069)
0.1 1.1 GO:0001709 cell fate determination(GO:0001709)
0.1 0.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.6 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.6 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.7 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.5 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.3 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.9 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 0.1 GO:0042220 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0090183 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.6 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.8 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.3 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.8 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 1.9 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.6 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.6 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.9 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.6 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.6 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.6 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 1.1 GO:0043236 laminin binding(GO:0043236)
0.0 0.5 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.3 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 1.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0016496 substance P receptor activity(GO:0016496)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.0 0.1 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.1 GO:0019838 growth factor binding(GO:0019838)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism