Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for vsx1_shox_shox2_uncx4.1_lhx2a

Z-value: 0.94

Motif logo

logo of logo of logo of logo of logo of

Transcription factors associated with vsx1_shox_shox2_uncx4.1_lhx2a

Gene Symbol Gene ID Gene Info
vsx1
ENSDARG00000056292 visual system homeobox 1 homolog, chx10-like
vsx1
ENSDARG00000109766 visual system homeobox 1 homolog, chx10-like
shox
ENSDARG00000025891 short stature homeobox
shox2
ENSDARG00000075713 short stature homeobox 2
uncx4.1
ENSDARG00000037760 Unc4.1 homeobox (C. elegans)
lhx2a
ENSDARG00000037964 LIM homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
shox2dr11_v1_chr15_-_2188332_2188422-0.801.0e-02Click!
vsx1dr11_v1_chr17_-_21066075_21066105-0.684.2e-02Click!
shoxdr11_v1_chr9_+_34641237_34641237-0.627.8e-02Click!
uncx4.1dr11_v1_chr1_+_9290103_9290103-0.608.6e-02Click!
lhx2adr11_v1_chr21_-_8420830_8420830-0.571.1e-01Click!

Activity profile of vsx1_shox_shox2_uncx4.1_lhx2a motif

Sorted Z-values of vsx1_shox_shox2_uncx4.1_lhx2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25777425 6.25 ENSDART00000021620
cldnd
claudin d
chr18_-_40708537 5.44 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr10_-_21362071 5.18 ENSDART00000125167
avd
avidin
chr10_-_21362320 5.07 ENSDART00000189789
avd
avidin
chr10_-_34915886 4.93 ENSDART00000141201
ENSDART00000002166
ccna1
cyclin A1
chr24_+_12835935 4.59 ENSDART00000114762
nanog
nanog homeobox
chr8_+_45334255 4.56 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr10_+_6884627 4.49 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr11_-_44801968 4.38 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr10_-_34916208 4.38 ENSDART00000187371
ccna1
cyclin A1
chr11_-_6452444 3.93 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr9_-_35633827 3.45 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr20_-_23426339 3.10 ENSDART00000004625
zar1
zygote arrest 1
chr10_-_25217347 2.98 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr2_-_26596794 2.82 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr5_+_6954162 2.67 ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr10_-_34002185 2.54 ENSDART00000046599
zar1l
zygote arrest 1-like
chr8_-_20230559 2.51 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr2_+_6253246 2.44 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr24_+_1023839 2.41 ENSDART00000082526
zgc:111976
zgc:111976
chr20_-_45060241 2.41 ENSDART00000185227
klhl29
kelch-like family member 29
chr20_-_6532462 2.40 ENSDART00000054653
mcm3l
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr19_+_2631565 2.35 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr1_+_35985813 2.33 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
zgc:152968
chr19_-_20403507 2.31 ENSDART00000052603
ENSDART00000137590
dazl
deleted in azoospermia-like
chr11_-_1550709 2.29 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr19_-_20403845 2.29 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
dazl
deleted in azoospermia-like
chr14_+_34490445 2.29 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr1_-_18811517 2.25 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr2_-_38287987 2.24 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
si:ch211-14a17.6
chr5_+_37903790 2.18 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr2_-_15324837 2.16 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr1_-_55248496 2.07 ENSDART00000098615
nanos3
nanos homolog 3
chr2_-_38284648 1.92 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
si:ch211-14a17.7
chr8_-_20230802 1.91 ENSDART00000063400
mllt1a
MLLT1, super elongation complex subunit a
chr16_+_29509133 1.89 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr6_-_43283122 1.77 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr2_+_41526904 1.75 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr10_-_32494499 1.73 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr12_-_6880694 1.69 ENSDART00000171846
pcdh15b
protocadherin-related 15b
chr16_+_39159752 1.69 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr16_-_42056137 1.68 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr11_+_31864921 1.56 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr14_+_35428152 1.54 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr13_-_31017960 1.54 ENSDART00000145287
wdfy4
WDFY family member 4
chr10_-_32494304 1.53 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr13_+_38817871 1.51 ENSDART00000187708
col19a1
collagen, type XIX, alpha 1
chr14_-_8940499 1.47 ENSDART00000129030
zgc:153681
zgc:153681
chr17_-_41798856 1.46 ENSDART00000156031
ENSDART00000192801
ENSDART00000180172
ENSDART00000084745
ENSDART00000175577
ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr18_-_43884044 1.43 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr10_+_6884123 1.43 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr6_+_40922572 1.39 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr7_-_48263516 1.39 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
rbpms2b
RNA binding protein with multiple splicing 2b
chr9_+_29548195 1.37 ENSDART00000176057
rnf17
ring finger protein 17
chr8_+_11425048 1.36 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr2_+_41926707 1.34 ENSDART00000023208
zgc:110183
zgc:110183
chr17_+_16046132 1.34 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr11_+_18183220 1.32 ENSDART00000113468
LO018315.10

chr8_+_11325310 1.31 ENSDART00000142577
fxn
frataxin
chr4_+_13586689 1.28 ENSDART00000067161
ENSDART00000138201
tnpo3
transportin 3
chr15_-_25099679 1.26 ENSDART00000154628
rflnb
refilin B
chr22_+_17261801 1.23 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tdrd5
tudor domain containing 5
chr16_+_25116827 1.21 ENSDART00000163244
si:ch211-261d7.6
si:ch211-261d7.6
chr4_+_11723852 1.20 ENSDART00000028820
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr15_-_43284021 1.19 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr5_+_57924611 1.18 ENSDART00000050949
btg4
B-cell translocation gene 4
chr15_-_16177603 1.17 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr24_-_25144441 1.16 ENSDART00000152104
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr4_+_9467049 1.15 ENSDART00000012659
zgc:55888
zgc:55888
chr15_+_31344472 1.13 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
or107-1
odorant receptor, family D, subfamily 107, member 1
chr17_-_2690083 1.11 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr6_-_40922971 1.09 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr21_-_28640316 1.07 ENSDART00000128237
nrg2a
neuregulin 2a
chr22_-_20924564 1.07 ENSDART00000100642
ENSDART00000032770
ell
elongation factor RNA polymerase II
chr16_-_29387215 1.06 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr9_-_50001606 1.06 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr1_-_6028876 1.04 ENSDART00000168117
si:ch1073-345a8.1
si:ch1073-345a8.1
chr13_-_31008275 1.04 ENSDART00000139394
wdfy4
WDFY family member 4
chr21_-_32060993 1.03 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr5_-_68333081 1.03 ENSDART00000168786
h1m
linker histone H1M
chr1_-_40102836 1.03 ENSDART00000147317
cntf
ciliary neurotrophic factor
chr17_-_6613458 1.01 ENSDART00000175024
si:ch211-189e2.3
si:ch211-189e2.3
chr12_-_33579873 1.01 ENSDART00000184661
tdrkh
tudor and KH domain containing
chr19_+_15441022 1.00 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr2_+_20793982 1.00 ENSDART00000014785
prg4a
proteoglycan 4a
chr17_+_16046314 0.99 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr2_-_55298075 0.98 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr7_+_34592526 0.98 ENSDART00000173959
fhod1
formin homology 2 domain containing 1
chr17_-_30635298 0.97 ENSDART00000155478
sh3yl1
SH3 and SYLF domain containing 1
chr11_+_35171406 0.96 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr20_-_37813863 0.95 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr23_+_38957472 0.95 ENSDART00000193836
ATP9A
ATPase phospholipid transporting 9A (putative)
chr23_-_31913069 0.94 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr10_-_13343831 0.92 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr14_-_33945692 0.90 ENSDART00000168546
ENSDART00000189778
zdhhc24
zinc finger, DHHC-type containing 24
chr16_+_2820340 0.90 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
si:dkey-288i20.2
chr6_-_12172424 0.89 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr13_-_25720876 0.87 ENSDART00000142404
ENSDART00000146487
si:dkey-192p21.6
si:dkey-192p21.6
chr11_-_40418975 0.87 ENSDART00000086296
trim62
tripartite motif containing 62
chr21_-_37963141 0.85 ENSDART00000180331
si:dkey-38k9.5
si:dkey-38k9.5
chr3_+_28860283 0.85 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr8_+_41037541 0.85 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr23_+_2728095 0.85 ENSDART00000066086
zgc:114123
zgc:114123
chr24_-_2450597 0.85 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr22_+_9003090 0.83 ENSDART00000106414
rnh1
ribonuclease/angiogenin inhibitor 1
chr19_-_19379084 0.83 ENSDART00000165206
smarcc1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr1_+_18811679 0.82 ENSDART00000078610
slc25a51a
solute carrier family 25, member 51a
chr22_+_18315490 0.82 ENSDART00000160413
gatad2ab
GATA zinc finger domain containing 2Ab
chr13_+_38814521 0.81 ENSDART00000110976
col19a1
collagen, type XIX, alpha 1
chr19_-_20403318 0.80 ENSDART00000136826
dazl
deleted in azoospermia-like
chr23_-_17003533 0.79 ENSDART00000080545
dnmt3bb.2
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr19_-_30510259 0.79 ENSDART00000135128
ENSDART00000186169
ENSDART00000182974
ENSDART00000187797
bag6l
BCL2 associated athanogene 6, like
chr17_+_21546993 0.79 ENSDART00000182387
chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr10_-_21545091 0.77 ENSDART00000029122
ENSDART00000132207
zgc:165539
zgc:165539
chr13_+_40501455 0.76 ENSDART00000114985
hpse2
heparanase 2
chr24_-_30862168 0.75 ENSDART00000168540
ptbp2a
polypyrimidine tract binding protein 2a
chr7_-_71389375 0.72 ENSDART00000128928
CABZ01074298.1

chr22_-_17653143 0.72 ENSDART00000089171
hmha1b
histocompatibility (minor) HA-1 b
chr25_+_35891342 0.71 ENSDART00000147093
lsm14aa
LSM14A mRNA processing body assembly factor a
chr3_-_30488063 0.71 ENSDART00000055393
ENSDART00000151367
med25
mediator complex subunit 25
chr6_-_25163722 0.70 ENSDART00000192225
znf326
zinc finger protein 326
chr19_+_21362553 0.70 ENSDART00000122002
tshz1
teashirt zinc finger homeobox 1
chr12_+_26877381 0.68 ENSDART00000087329
znf438
zinc finger protein 438
chr2_-_15318786 0.67 ENSDART00000135851
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr23_-_33709964 0.67 ENSDART00000143333
ENSDART00000130338
pou6f1
POU class 6 homeobox 1
chr20_-_19511016 0.67 ENSDART00000168521
snx17
sorting nexin 17
chr18_-_15551360 0.67 ENSDART00000159915
ENSDART00000172690
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr6_+_21001264 0.67 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr15_+_12429206 0.65 ENSDART00000168997
tmprss4a
transmembrane protease, serine 4a
chr16_+_42471455 0.65 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr23_+_38251864 0.65 ENSDART00000183498
ENSDART00000129593
znf217
zinc finger protein 217
chr20_-_28800999 0.65 ENSDART00000049462
rab15
RAB15, member RAS oncogene family
chr9_+_50001746 0.64 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr5_-_30074332 0.64 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr25_-_27621268 0.64 ENSDART00000146205
ENSDART00000073511
hyal6
hyaluronoglucosaminidase 6
chr5_-_25733745 0.64 ENSDART00000051566
zgc:101016
zgc:101016
chr20_+_32523576 0.64 ENSDART00000147319
scml4
Scm polycomb group protein like 4
chr10_+_17371356 0.63 ENSDART00000122663
sppl3
signal peptide peptidase 3
chr19_-_5103141 0.63 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr12_+_30367371 0.62 ENSDART00000153364
ccdc186
si:ch211-225b10.4
chr20_-_40758410 0.62 ENSDART00000183031
cx34.5
connexin 34.5
chr7_-_51773166 0.61 ENSDART00000054591
bmp15
bone morphogenetic protein 15
chr14_-_32631013 0.61 ENSDART00000176815
atp11c
ATPase phospholipid transporting 11C
chr3_-_26787430 0.61 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr11_+_44804685 0.61 ENSDART00000163660
strn
striatin, calmodulin binding protein
chr11_+_12052791 0.61 ENSDART00000158479
si:ch211-156l18.8
si:ch211-156l18.8
chr10_-_33297864 0.61 ENSDART00000163360
PRDM15
PR/SET domain 15
chr24_+_40860320 0.60 ENSDART00000161351
gorasp1b
golgi reassembly stacking protein 1b
chr8_-_23780334 0.60 ENSDART00000145179
ENSDART00000145894
zgc:195245
zgc:195245
chr21_-_25801956 0.60 ENSDART00000101219
mettl27
methyltransferase like 27
chr2_-_38363017 0.60 ENSDART00000088026
prmt5
protein arginine methyltransferase 5
chr23_-_31913231 0.60 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr4_-_77125693 0.60 ENSDART00000174256
CU467646.3

chr20_-_29864390 0.59 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr17_+_37227936 0.59 ENSDART00000076009
hadhab
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b
chr11_+_18873619 0.59 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr19_-_19556778 0.58 ENSDART00000164060
tax1bp1a
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr7_+_23292133 0.58 ENSDART00000134489
htr2cl1
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1
chr3_-_26183699 0.58 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr17_+_19630272 0.58 ENSDART00000104895
rgs7a
regulator of G protein signaling 7a
chr12_+_47698356 0.57 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr7_+_24645186 0.57 ENSDART00000150118
ENSDART00000150233
ENSDART00000087691
gba2
glucosidase, beta (bile acid) 2
chr8_+_7801060 0.57 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr8_+_50953776 0.57 ENSDART00000013870
zgc:56596
zgc:56596
chr20_+_29209767 0.56 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr13_-_4018888 0.56 ENSDART00000058238
tjap1
tight junction associated protein 1 (peripheral)
chr17_+_10738126 0.55 ENSDART00000051527
tbpl2
TATA box binding protein like 2
chr16_-_17347727 0.55 ENSDART00000144392
zyx
zyxin
chr10_+_17235370 0.54 ENSDART00000038780
sppl3
signal peptide peptidase 3
chr14_+_23184517 0.54 ENSDART00000181410
enox2
ecto-NOX disulfide-thiol exchanger 2
chr2_+_50608099 0.53 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr5_-_20491198 0.53 ENSDART00000183051
ENSDART00000144232
ficd
FIC domain containing
chr15_-_31237362 0.53 ENSDART00000145255
ENSDART00000193299
ENSDART00000181838
ENSDART00000182139
cuedc1b
CUE domain containing 1b
chr2_-_38206034 0.53 ENSDART00000144518
ENSDART00000137395
acin1a
apoptotic chromatin condensation inducer 1a
chr11_+_18130300 0.53 ENSDART00000169146
zgc:175135
zgc:175135
chr15_-_30857350 0.53 ENSDART00000138988
akap1b
A kinase (PRKA) anchor protein 1b
chr11_+_18157260 0.53 ENSDART00000144659
zgc:173545
zgc:173545
chr5_+_66433287 0.52 ENSDART00000170757
kntc1
kinetochore associated 1
chr3_+_18807006 0.52 ENSDART00000180091
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr25_+_11456696 0.51 ENSDART00000171408
AGBL1
si:ch73-141f14.1
chr14_+_26247319 0.51 ENSDART00000192793
CCDC69
coiled-coil domain containing 69
chr24_+_19415124 0.51 ENSDART00000186931
sulf1
sulfatase 1
chr7_+_25221757 0.51 ENSDART00000173551
exoc6b
exocyst complex component 6B
chr17_-_49438873 0.50 ENSDART00000004424
znf292a
zinc finger protein 292a
chr16_-_16120941 0.50 ENSDART00000131227
ankib1b
ankyrin repeat and IBR domain containing 1b
chr7_-_23768234 0.50 ENSDART00000173981
si:ch211-200p22.4
si:ch211-200p22.4
chr5_-_69312533 0.50 ENSDART00000082614
ENSDART00000183098
smtnb
smoothelin b
chr16_+_28994709 0.50 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr22_+_17828267 0.50 ENSDART00000136016
hapln4
hyaluronan and proteoglycan link protein 4
chr8_-_19051906 0.49 ENSDART00000089024
sema6bb
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
chr10_-_35103208 0.49 ENSDART00000192734
zgc:110006
zgc:110006
chr17_-_24575893 0.49 ENSDART00000141914
aftphb
aftiphilin b
chr12_+_30367079 0.49 ENSDART00000190112
ccdc186
si:ch211-225b10.4
chr14_-_33481428 0.49 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr23_-_29553430 0.49 ENSDART00000157773
ENSDART00000126384
ube4b
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr4_-_77116266 0.49 ENSDART00000174249
CU467646.2

chr4_-_77130289 0.49 ENSDART00000174380
CU467646.7

chr10_-_11261565 0.48 ENSDART00000146727
ptbp3
polypyrimidine tract binding protein 3
chr2_-_57076687 0.48 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr21_+_34088110 0.48 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
mtmr1b
myotubularin related protein 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of vsx1_shox_shox2_uncx4.1_lhx2a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.9 5.4 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.9 2.7 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.8 2.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.5 2.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.5 8.3 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.4 1.8 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.4 1.7 GO:0060074 synapse maturation(GO:0060074)
0.4 1.3 GO:1903011 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.3 2.4 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.3 5.9 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.3 0.6 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.3 1.4 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.3 2.1 GO:0034063 stress granule assembly(GO:0034063)
0.2 3.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 0.9 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 1.5 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 0.9 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.2 3.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 9.7 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.2 0.6 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.2 0.6 GO:0006089 lactate metabolic process(GO:0006089)
0.2 1.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2 3.1 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 0.8 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 1.1 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.1 0.6 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.4 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.7 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.4 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.4 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.1 1.2 GO:0006465 signal peptide processing(GO:0006465)
0.1 5.6 GO:0060968 regulation of gene silencing(GO:0060968)
0.1 0.4 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 1.3 GO:0007143 female meiotic division(GO:0007143)
0.1 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.5 GO:0007624 ultradian rhythm(GO:0007624)
0.1 0.5 GO:0000012 single strand break repair(GO:0000012)
0.1 0.3 GO:2000376 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.1 0.5 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.5 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 2.8 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.3 GO:0051645 Golgi localization(GO:0051645)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.5 GO:0035627 ceramide transport(GO:0035627)
0.1 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.5 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.4 GO:0070285 pigment cell development(GO:0070285)
0.1 0.2 GO:0048785 hatching gland development(GO:0048785)
0.1 1.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.2 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.3 GO:0016246 RNA interference(GO:0016246)
0.1 0.2 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 0.5 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 5.0 GO:0017148 negative regulation of translation(GO:0017148)
0.1 0.3 GO:0055071 manganese ion homeostasis(GO:0055071)
0.1 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.4 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.2 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 1.3 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.6 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.2 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 1.0 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.3 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.3 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.3 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.2 GO:0034505 tooth mineralization(GO:0034505)
0.0 2.2 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.3 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.9 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 1.2 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.5 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.4 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.5 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 1.0 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 2.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 1.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.8 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 2.0 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.4 GO:0008354 germ cell migration(GO:0008354)
0.0 0.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.2 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 1.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.4 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.4 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 0.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.0 0.6 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 2.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.6 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.2 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.4 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.4 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.3 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.1 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.0 0.2 GO:0045471 response to ethanol(GO:0045471)
0.0 0.4 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.1 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:1903321 negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.0 0.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.9 2.7 GO:0097189 apoptotic body(GO:0097189)
0.4 1.2 GO:0033391 chromatoid body(GO:0033391)
0.4 1.8 GO:0070724 BMP receptor complex(GO:0070724)
0.3 1.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 8.2 GO:0043186 P granule(GO:0043186)
0.2 1.4 GO:0071818 BAT3 complex(GO:0071818)
0.2 0.7 GO:0044609 DBIRD complex(GO:0044609)
0.2 6.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 0.5 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 2.5 GO:0042555 MCM complex(GO:0042555)
0.1 3.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 10.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.7 GO:0032420 stereocilium(GO:0032420)
0.1 0.4 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0070390 transcription export complex 2(GO:0070390)
0.1 3.9 GO:0016592 mediator complex(GO:0016592)
0.1 0.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.3 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 1.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.4 GO:0043296 apical junction complex(GO:0043296)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.4 GO:0032432 actin filament bundle(GO:0032432)
0.0 2.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 3.4 GO:0000323 lytic vacuole(GO:0000323)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 4.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0097546 ciliary base(GO:0097546)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 10.2 GO:0009374 biotin binding(GO:0009374)
0.6 5.4 GO:0008494 translation activator activity(GO:0008494)
0.5 8.3 GO:0032190 acrosin binding(GO:0032190)
0.5 2.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 1.3 GO:0031005 filamin binding(GO:0031005)
0.3 4.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 0.9 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.2 3.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.2 0.6 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 0.6 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 0.5 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 0.5 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.2 9.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.1 GO:0016530 metallochaperone activity(GO:0016530)
0.1 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.9 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.4 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.1 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 7.9 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.3 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.1 2.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.5 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.6 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.6 GO:0019894 kinesin binding(GO:0019894)
0.1 0.6 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.2 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.3 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 1.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 3.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.8 GO:0070628 proteasome binding(GO:0070628)
0.1 0.2 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.1 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 2.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 10.7 GO:0042802 identical protein binding(GO:0042802)
0.0 1.1 GO:0031267 small GTPase binding(GO:0031267)
0.0 3.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 1.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.9 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.5 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.7 GO:0004527 exonuclease activity(GO:0004527)
0.0 9.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.6 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.1 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 2.1 GO:0000149 SNARE binding(GO:0000149)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 2.4 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0030276 clathrin binding(GO:0030276)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.3 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID P73PATHWAY p73 transcription factor network
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 2.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 1.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling