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PRJNA195909:zebrafish embryo and larva development

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Results for zbtb16a+zbtb16b

Z-value: 1.84

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Transcription factors associated with zbtb16a+zbtb16b

Gene Symbol Gene ID Gene Info
zbtb16a
ENSDARG00000007184 zinc finger and BTB domain containing 16a
zbtb16b
ENSDARG00000074526 zinc finger and BTB domain containing 16b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb16adr11_v1_chr21_-_23331619_23331619-0.723.0e-02Click!
zbtb16bdr11_v1_chr15_-_18361475_18361475-0.713.1e-02Click!

Activity profile of zbtb16a+zbtb16b motif

Sorted Z-values of zbtb16a+zbtb16b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_24838857 4.79 ENSDART00000179766
ENSDART00000180892
fam113
family with sequence similarity 113
chr7_+_17947217 4.64 ENSDART00000101601
cth1
cysteine three histidine 1
chr7_-_24838367 4.41 ENSDART00000139455
ENSDART00000012483
ENSDART00000131530
fam113
family with sequence similarity 113
chr19_-_27588842 2.59 ENSDART00000121643
si:dkeyp-46h3.2
si:dkeyp-46h3.2
chr12_-_33359052 2.36 ENSDART00000135943
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr8_-_6825588 2.35 ENSDART00000135834
dock5
dedicator of cytokinesis 5
chr21_-_43636595 2.21 ENSDART00000151115
ENSDART00000151486
ENSDART00000151778
si:ch1073-263o8.2
si:ch1073-263o8.2
chr22_+_1170294 2.17 ENSDART00000159761
ENSDART00000169809
irf6
interferon regulatory factor 6
chr18_+_11858397 2.13 ENSDART00000133762
tmtc2b
transmembrane and tetratricopeptide repeat containing 2b
chr14_-_7045009 2.11 ENSDART00000112082
rufy1
RUN and FYVE domain containing 1
chr23_+_19213472 2.04 ENSDART00000185985
apobec2b
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2b
chr2_+_44512324 2.01 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
pask
PAS domain containing serine/threonine kinase
chr25_+_34888886 2.00 ENSDART00000035245
spire2
spire-type actin nucleation factor 2
chr6_-_53885514 1.96 ENSDART00000173812
ENSDART00000127144
cacna2d2a
calcium channel, voltage-dependent, alpha 2/delta subunit 2a
chr15_+_12435975 1.94 ENSDART00000168011
tmprss4a
transmembrane protease, serine 4a
chr14_-_32876280 1.92 ENSDART00000173168
si:rp71-46j2.7
si:rp71-46j2.7
chr1_+_34203817 1.80 ENSDART00000191432
ENSDART00000046094
arl6
ADP-ribosylation factor-like 6
chr5_+_45140914 1.78 ENSDART00000172702
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_-_425145 1.77 ENSDART00000164905
dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr19_+_15441022 1.77 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr7_-_24520866 1.77 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr3_+_18807006 1.75 ENSDART00000180091
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr21_-_2341937 1.75 ENSDART00000158459
zgc:193790
zgc:193790
chr10_+_44146287 1.63 ENSDART00000162176
grk3
G protein-coupled receptor kinase 3
chr4_-_2168805 1.62 ENSDART00000150039
kcnc2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr21_-_22117085 1.60 ENSDART00000146673
slc35f2
solute carrier family 35, member F2
chr19_-_3876877 1.60 ENSDART00000163711
thrap3b
thyroid hormone receptor associated protein 3b
chr18_+_14342326 1.57 ENSDART00000181013
ENSDART00000138372
si:dkey-246g23.2
si:dkey-246g23.2
chr8_+_28724692 1.55 ENSDART00000140115
ccser1
coiled-coil serine-rich protein 1
chr3_-_26190804 1.52 ENSDART00000136001
ypel3
yippee-like 3
chr5_-_45958838 1.51 ENSDART00000135072
poc5
POC5 centriolar protein homolog (Chlamydomonas)
chr10_+_575929 1.50 ENSDART00000129856
smad4a
SMAD family member 4a
chr2_-_11027258 1.50 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
ssbp3a
single stranded DNA binding protein 3a
chr13_-_24429066 1.47 ENSDART00000147514
ENSDART00000057588
cep68
centrosomal protein 68
chr17_-_12249990 1.47 ENSDART00000177889
ENSDART00000155545
ahctf1
AT hook containing transcription factor 1
chr14_+_24840669 1.45 ENSDART00000106039
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr11_+_6902306 1.43 ENSDART00000075993
crtc1b
CREB regulated transcription coactivator 1b
chr15_+_45994123 1.40 ENSDART00000124704
lrfn1
leucine rich repeat and fibronectin type III domain containing 1
chr23_-_15916316 1.37 ENSDART00000134096
ENSDART00000042469
ENSDART00000146605
mrgbp
MRG/MORF4L binding protein
chr9_+_45227028 1.36 ENSDART00000185579
adarb1b
adenosine deaminase, RNA-specific, B1b
chr1_+_44173245 1.36 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr9_+_34232503 1.34 ENSDART00000132836
nxpe3
neurexophilin and PC-esterase domain family, member 3
chr18_+_3243292 1.32 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr20_-_24182689 1.32 ENSDART00000171184
map3k7
mitogen-activated protein kinase kinase kinase 7
chr21_+_10712823 1.31 ENSDART00000123476
lman1
lectin, mannose-binding, 1
chr15_-_25094026 1.30 ENSDART00000129154
exo5
exonuclease 5
chr19_-_4137087 1.29 ENSDART00000164611
rragcb
Ras-related GTP binding Cb
chr5_+_66250856 1.26 ENSDART00000132789
secisbp2
SECIS binding protein 2
chr19_-_33996277 1.25 ENSDART00000159384
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr2_-_7757273 1.25 ENSDART00000136074
b3gnt5b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5b
chr1_+_49955869 1.23 ENSDART00000150517
gstcd
glutathione S-transferase, C-terminal domain containing
chr12_-_34258384 1.19 ENSDART00000109196
pgs1
phosphatidylglycerophosphate synthase 1
chr15_-_25093680 1.19 ENSDART00000062695
exo5
exonuclease 5
chr10_-_17745345 1.19 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
si:dkey-200l5.4
chr25_-_27665978 1.18 ENSDART00000123590
si:ch211-91p5.3
si:ch211-91p5.3
chr5_+_58421536 1.18 ENSDART00000173410
ccdc15
coiled-coil domain containing 15
chr12_+_33460794 1.17 ENSDART00000007053
ENSDART00000142716
narf
nuclear prelamin A recognition factor
chr8_+_19624589 1.16 ENSDART00000185698
slc35a3a
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr25_-_998096 1.14 ENSDART00000164082
znf609a
zinc finger protein 609a
chr20_+_1316495 1.13 ENSDART00000064439
nup43
nucleoporin 43
chr22_-_31020690 1.13 ENSDART00000130604
ssuh2.4
ssu-2 homolog, tandem duplicate 4
chr1_-_38361496 1.12 ENSDART00000015323
fbxo8
F-box protein 8
chr20_+_41906960 1.11 ENSDART00000193460
cep85l
centrosomal protein 85, like
chr21_+_18907102 1.11 ENSDART00000160185
ENSDART00000190175
ENSDART00000017937
ENSDART00000191546
ENSDART00000130519
ENSDART00000137143
smpd4
sphingomyelin phosphodiesterase 4
chr1_+_29766725 1.11 ENSDART00000054064
zc3h13
zinc finger CCCH-type containing 13
chr7_-_12789251 1.09 ENSDART00000052750
adamtsl3
ADAMTS-like 3
chr7_-_51709721 1.09 ENSDART00000136047
hdac8
histone deacetylase 8
chr14_-_14659023 1.09 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr24_-_2450597 1.09 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr13_+_39182099 1.08 ENSDART00000131434
fam135a
family with sequence similarity 135, member A
chr4_+_10003523 1.08 ENSDART00000148105
naf1
nuclear assembly factor 1 homolog (S. cerevisiae)
chr7_-_24875421 1.07 ENSDART00000173920
adad2
adenosine deaminase domain containing 2
chr23_+_2666944 1.07 ENSDART00000192861
CABZ01057928.1

chr5_-_71765780 1.07 ENSDART00000011955
gpsm1b
G protein signaling modulator 1b
chr25_+_19541019 1.06 ENSDART00000141056
ENSDART00000027740
nedd1
neural precursor cell expressed, developmentally down-regulated 1
chr1_+_2712956 1.05 ENSDART00000126093
gpc6a
glypican 6a
chr10_-_32494499 1.05 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr17_+_16429826 1.05 ENSDART00000136078
efcab11
EF-hand calcium binding domain 11
chr19_+_43753995 1.04 ENSDART00000058504
SLC17A3
si:ch1073-513e17.1
chr4_+_5868034 1.03 ENSDART00000166591
utp20
UTP20 small subunit (SSU) processome component
chr23_-_27506161 1.02 ENSDART00000145007
asb8
ankyrin repeat and SOCS box containing 8
chr25_-_997894 1.01 ENSDART00000169011
znf609a
zinc finger protein 609a
chr11_+_19370717 1.01 ENSDART00000165906
prickle2b
prickle homolog 2b
chr6_-_30689126 1.00 ENSDART00000065211
pars2
prolyl-tRNA synthetase 2, mitochondrial
chr6_+_3730843 1.00 ENSDART00000019630
FO704755.1

chr21_+_3093419 0.99 ENSDART00000162520
SHC3
SHC adaptor protein 3
chr17_+_6469419 0.97 ENSDART00000191729
COQ8A (1 of many)
si:dkey-36g24.3
chr18_+_15841449 0.97 ENSDART00000141800
ENSDART00000091349
eea1
early endosome antigen 1
chr10_-_32494304 0.95 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr11_-_21404358 0.92 ENSDART00000129062
ikbke
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr6_+_6828167 0.92 ENSDART00000181284
si:ch211-85n16.4
si:ch211-85n16.4
chr3_-_25148047 0.92 ENSDART00000089325
mief1
mitochondrial elongation factor 1
chr11_-_23080970 0.92 ENSDART00000127791
atp2b2
ATPase plasma membrane Ca2+ transporting 2
chr22_-_9889413 0.91 ENSDART00000081450
si:dkey-253d23.5
si:dkey-253d23.5
chr13_+_11828516 0.91 ENSDART00000110141
sufu
suppressor of fused homolog (Drosophila)
chr15_-_44663712 0.91 ENSDART00000192124
CABZ01061894.1

chr23_-_27505825 0.90 ENSDART00000137229
ENSDART00000013797
asb8
ankyrin repeat and SOCS box containing 8
chr11_+_19370447 0.89 ENSDART00000186154
prickle2b
prickle homolog 2b
chr25_+_18475032 0.89 ENSDART00000073564
tes
testis derived transcript (3 LIM domains)
chr15_+_38221038 0.88 ENSDART00000188149
stim1a
stromal interaction molecule 1a
chr22_+_9522971 0.88 ENSDART00000110048
strip1
striatin interacting protein 1
chr9_-_1484202 0.87 ENSDART00000181215
rbm45
RNA binding motif protein 45
chr15_-_26931541 0.87 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr8_+_47342586 0.87 ENSDART00000007624
plch2a
phospholipase C, eta 2a
chr2_+_54696042 0.87 ENSDART00000074270
ankrd12
ankyrin repeat domain 12
chr7_-_51710015 0.87 ENSDART00000009184
hdac8
histone deacetylase 8
chr12_-_33746111 0.86 ENSDART00000127203
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr3_-_52683241 0.85 ENSDART00000155248
si:dkey-210j14.5
si:dkey-210j14.5
chr8_-_32354677 0.84 ENSDART00000138268
ENSDART00000133245
ENSDART00000179677
ENSDART00000174450
ipo11
importin 11
chr16_+_26747766 0.84 ENSDART00000183257
rad54b
RAD54 homolog B (S. cerevisiae)
chr7_+_39664055 0.84 ENSDART00000146171
zgc:158564
zgc:158564
chr18_-_42071876 0.83 ENSDART00000193288
ENSDART00000189021
ENSDART00000019245
arhgap42b
Rho GTPase activating protein 42b
chr11_-_2456656 0.82 ENSDART00000171219
ENSDART00000167938
slc2a10
solute carrier family 2 (facilitated glucose transporter), member 10
chr8_+_10350122 0.81 ENSDART00000186650
ENSDART00000098009
tbc1d22b
TBC1 domain family, member 22B
chr21_-_21527983 0.80 ENSDART00000014254
diablob
diablo, IAP-binding mitochondrial protein b
chr4_-_37587110 0.80 ENSDART00000169302
znf1100
zinc finger protein 1100
chr5_-_23705828 0.79 ENSDART00000189419
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr3_+_34120191 0.78 ENSDART00000020017
ENSDART00000151700
aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr4_+_64921810 0.78 ENSDART00000157654
BX928743.1

chr2_+_5841108 0.77 ENSDART00000136180
dis3l2
DIS3 like 3'-5' exoribonuclease 2
chr18_-_44527124 0.77 ENSDART00000189471
aplp2
amyloid beta (A4) precursor-like protein 2
chr4_+_45274792 0.77 ENSDART00000150295
znf1138
zinc finger protein 1138
chr11_-_27917730 0.74 ENSDART00000173219
eif4g3a
eukaryotic translation initiation factor 4 gamma, 3a
chr22_-_27113332 0.74 ENSDART00000146951
ENSDART00000178855
xpnpep1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr9_-_43207768 0.73 ENSDART00000192523
sestd1
SEC14 and spectrin domains 1
chr2_-_55298075 0.73 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr8_-_45867358 0.73 ENSDART00000132810
adam9
ADAM metallopeptidase domain 9
chr15_+_38221196 0.72 ENSDART00000122134
ENSDART00000190099
stim1a
stromal interaction molecule 1a
chr21_-_9383974 0.72 ENSDART00000160932
sdad1
SDA1 domain containing 1
chr10_-_7666810 0.71 ENSDART00000191479
pcyox1
prenylcysteine oxidase 1
chr6_-_60049272 0.70 ENSDART00000057466
ccndbp1
cyclin D-type binding-protein 1
chr8_+_3820134 0.69 ENSDART00000122454
citb
citron rho-interacting serine/threonine kinase b
chr18_-_16885362 0.69 ENSDART00000132778
swap70b
switching B cell complex subunit SWAP70b
chr7_+_61184104 0.68 ENSDART00000110671
zgc:194930
zgc:194930
chr9_-_34882516 0.68 ENSDART00000011163
asmtl
acetylserotonin O-methyltransferase-like
chr2_-_41124013 0.68 ENSDART00000134756
hs6st1a
heparan sulfate 6-O-sulfotransferase 1a
chr19_+_15440841 0.67 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr21_-_13225402 0.67 ENSDART00000080347
wdr34
WD repeat domain 34
chr25_-_35104083 0.67 ENSDART00000183252
ENSDART00000156727
si:dkey-108k21.21
si:dkey-108k21.21
chr6_-_14040136 0.66 ENSDART00000065361
ENSDART00000179765
etv5b
ets variant 5b
chr18_+_41250938 0.66 ENSDART00000087566
trip12
thyroid hormone receptor interactor 12
chr3_-_13509283 0.66 ENSDART00000166832
slc25a19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr25_-_7709797 0.65 ENSDART00000157076
prdm11
PR domain containing 11
chr14_-_33312407 0.65 ENSDART00000135700
sept6
septin 6
chr10_+_36439293 0.64 ENSDART00000043802
uspl1
ubiquitin specific peptidase like 1
chr13_-_37474989 0.64 ENSDART00000114136
wdr89
WD repeat domain 89
chr17_-_13058515 0.63 ENSDART00000172450
ENSDART00000170255
CU469462.1

chr9_-_1483879 0.63 ENSDART00000093415
rbm45
RNA binding motif protein 45
chr16_+_20947439 0.63 ENSDART00000137344
skap2
src kinase associated phosphoprotein 2
chr8_+_12951155 0.63 ENSDART00000081601
cept1a
choline/ethanolamine phosphotransferase 1a
chr22_+_6740039 0.63 ENSDART00000144122
CT583625.2

chr4_+_9360532 0.62 ENSDART00000189971
ipo8
importin 8
chr16_+_51159775 0.61 ENSDART00000161924
dhdds
dehydrodolichyl diphosphate synthase
chr11_-_889845 0.61 ENSDART00000162152
atg7
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr4_+_37503994 0.60 ENSDART00000158217
znf1102
zinc finger protein 1102
chr16_+_36126310 0.60 ENSDART00000166040
ENSDART00000189802
sh3bp5b
SH3-domain binding protein 5b (BTK-associated)
chr6_+_11681011 0.60 ENSDART00000151447
ENSDART00000151618
calcrlb
calcitonin receptor-like b
chr11_+_24820542 0.60 ENSDART00000135443
kdm5ba
lysine (K)-specific demethylase 5Ba
chr8_+_24296639 0.60 ENSDART00000172002
ZNF335
si:ch211-269m15.3
chr17_-_31579715 0.60 ENSDART00000110167
ENSDART00000191092
rpap1
RNA polymerase II associated protein 1
chr9_+_8894788 0.59 ENSDART00000132068
naxd
NAD(P)HX dehydratase
chr16_+_28994709 0.59 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr15_+_22435460 0.59 ENSDART00000031976
tmem136a
transmembrane protein 136a
chr7_-_28568238 0.58 ENSDART00000173927
tmem9b
TMEM9 domain family, member B
chr15_+_23528810 0.58 ENSDART00000182309
si:dkey-182i3.8
si:dkey-182i3.8
chr4_-_64605318 0.58 ENSDART00000170391
znf1099
zinc finger protein 1099
chr4_-_64604842 0.57 ENSDART00000169862
znf1099
zinc finger protein 1099
chr10_+_29137482 0.57 ENSDART00000178280
picalma
phosphatidylinositol binding clathrin assembly protein a
chr11_+_6902946 0.56 ENSDART00000144006
crtc1b
CREB regulated transcription coactivator 1b
chr5_+_5398966 0.56 ENSDART00000139553
mapkap1
mitogen-activated protein kinase associated protein 1
chr9_+_32178050 0.56 ENSDART00000169526
coq10b
coenzyme Q10B
chr3_-_15645405 0.56 ENSDART00000133957
si:dkey-93n13.1
si:dkey-93n13.1
chr11_+_19603251 0.56 ENSDART00000005639
thoc7
THO complex 7
chr14_-_9085349 0.55 ENSDART00000054710
polr1d
polymerase (RNA) I polypeptide D
chr5_+_23207922 0.55 ENSDART00000187745
tpcn1
two pore segment channel 1
chr17_-_10738001 0.55 ENSDART00000051526
jmjd7
jumonji domain containing 7
chr4_-_30931296 0.54 ENSDART00000167727
znf1099
zinc finger protein 1099
chr12_-_13966184 0.54 ENSDART00000066368
klhl11
kelch-like family member 11
chr10_-_7636340 0.54 ENSDART00000166234
ubxn8
UBX domain protein 8
chr16_-_55259199 0.53 ENSDART00000161130
iqgap3
IQ motif containing GTPase activating protein 3
chr16_+_1100559 0.53 ENSDART00000092657
adamts16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr22_-_22242884 0.52 ENSDART00000020937
hdgfl2
HDGF like 2
chr6_+_55819038 0.52 ENSDART00000108786
si:ch211-81n22.1
si:ch211-81n22.1
chr16_-_29146624 0.52 ENSDART00000159814
ENSDART00000009826
mef2d
myocyte enhancer factor 2d
chr24_-_36238054 0.52 ENSDART00000155725
tmem241
transmembrane protein 241
chr4_-_69550757 0.52 ENSDART00000168344
znf1101
zinc finger protein 1101
chr2_-_15033136 0.52 ENSDART00000145974
ENSDART00000034865
hccsa.1
holocytochrome c synthase a
chr1_-_52447364 0.51 ENSDART00000140740
si:ch211-217k17.10
si:ch211-217k17.10
chr21_-_11970199 0.51 ENSDART00000114524
nop56
NOP56 ribonucleoprotein homolog
chr21_-_2348838 0.51 ENSDART00000160337
si:ch73-299h12.8
si:ch73-299h12.8
chr21_-_13051613 0.50 ENSDART00000190777
myorg
myogenesis regulating glycosidase (putative)
chr16_+_32729223 0.49 ENSDART00000125663
si:dkey-165n16.1
si:dkey-165n16.1
chr19_+_1097393 0.48 ENSDART00000168218
CABZ01111953.1

chr22_+_1421212 0.48 ENSDART00000161813
zgc:101130
zgc:101130
chr20_+_700616 0.48 ENSDART00000168166
senp6a
SUMO1/sentrin specific peptidase 6a
chr7_+_31051213 0.47 ENSDART00000148347
tjp1a
tight junction protein 1a
chr12_+_23912074 0.47 ENSDART00000152864
svila
supervillin a
chr10_+_36265164 0.46 ENSDART00000161060
or106-12
odorant receptor, family G, subfamily 106, member 12
chr21_-_41545995 0.45 ENSDART00000169977
bnip1b
BCL2 interacting protein 1b
chr20_-_47051996 0.45 ENSDART00000153330
dnmt3aa
DNA (cytosine-5-)-methyltransferase 3 alpha a

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb16a+zbtb16b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.4 1.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 0.9 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.3 1.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.3 1.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.3 2.0 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.3 2.0 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.3 2.0 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 2.0 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 1.6 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 1.4 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 0.9 GO:1900181 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.2 1.1 GO:0080009 mRNA methylation(GO:0080009)
0.2 0.7 GO:0015695 organic cation transport(GO:0015695)
0.2 2.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.2 0.7 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 0.9 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2 0.8 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2 0.8 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 1.2 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.1 1.6 GO:0003315 heart rudiment formation(GO:0003315)
0.1 1.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.7 GO:0030329 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.1 0.3 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.1 2.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.6 GO:1903405 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.6 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 1.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.1 0.5 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.1 1.1 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.7 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 1.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.7 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 4.0 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 0.5 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 0.6 GO:0090134 establishment or maintenance of cytoskeleton polarity(GO:0030952) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 2.3 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 2.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 1.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.1 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 2.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 1.9 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.3 GO:0048855 adenohypophysis morphogenesis(GO:0048855)
0.1 0.3 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 1.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.7 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 3.2 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 0.6 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.5 GO:0048264 determination of ventral identity(GO:0048264)
0.0 1.5 GO:0007632 visual behavior(GO:0007632)
0.0 0.8 GO:0030259 lipid glycosylation(GO:0030259)
0.0 1.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.0 0.5 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.5 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531) radial glial cell differentiation(GO:0060019)
0.0 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.4 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 1.3 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 1.3 GO:0001878 response to yeast(GO:0001878)
0.0 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.2 GO:0030826 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.6 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.8 GO:0008643 carbohydrate transport(GO:0008643)
0.0 1.3 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 1.1 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907) determination of liver left/right asymmetry(GO:0071910)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 1.3 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:1901998 toxin transport(GO:1901998)
0.0 1.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.6 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 1.4 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.8 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.5 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.5 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 1.4 GO:0016573 histone acetylation(GO:0016573)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.6 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.8 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.4 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.6 GO:0042113 B cell activation(GO:0042113)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 0.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 2.5 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3 1.3 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.9 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.2 0.6 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.8 GO:0060170 ciliary membrane(GO:0060170)
0.1 1.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 0.4 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 2.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.6 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.8 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 1.2 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.0 GO:0030686 90S preribosome(GO:0030686)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 2.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.9 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.6 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 3.7 GO:0005730 nucleolus(GO:0005730)
0.0 0.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.0 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.0 GO:0043614 multi-eIF complex(GO:0043614)
0.0 1.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.4 1.2 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.3 1.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 1.2 GO:0005521 lamin binding(GO:0005521)
0.3 2.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 2.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 2.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 0.6 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 0.6 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.2 0.6 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.2 1.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.2 2.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 2.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.7 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.1 0.8 GO:0015616 DNA translocase activity(GO:0015616)
0.1 2.0 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.4 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.6 GO:0032183 SUMO binding(GO:0032183)
0.1 1.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.6 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 1.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.7 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.5 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 1.8 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 1.3 GO:0005537 mannose binding(GO:0005537)
0.1 0.7 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 1.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.5 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.3 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.6 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.5 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 1.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.2 GO:0070513 death domain binding(GO:0070513)
0.1 1.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.4 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.9 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.0 2.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.8 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.3 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.6 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 1.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.6 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.1 GO:0031072 heat shock protein binding(GO:0031072)
0.0 2.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 6.0 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 1.3 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.9 GO:0000149 SNARE binding(GO:0000149)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 2.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 2.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.1 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.6 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 2.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase