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PRJNA195909:zebrafish embryo and larva development

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Results for zbtb18+zbtb42

Z-value: 1.70

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Transcription factors associated with zbtb18+zbtb42

Gene Symbol Gene ID Gene Info
zbtb18
ENSDARG00000028228 zinc finger and BTB domain containing 18
zbtb42
ENSDARG00000102761 zinc finger and BTB domain containing 42

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb18dr11_v1_chr13_+_11436130_114361300.627.3e-02Click!
zbtb42dr11_v1_chr17_-_1407593_1407725-0.383.1e-01Click!

Activity profile of zbtb18+zbtb42 motif

Sorted Z-values of zbtb18+zbtb42 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_26282672 3.58 ENSDART00000176663
and1
actinodin1
chr25_+_31277415 3.01 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr23_+_21473103 2.78 ENSDART00000142921
si:ch73-21g5.7
si:ch73-21g5.7
chr23_-_21453614 2.69 ENSDART00000079274
her4.1
hairy-related 4, tandem duplicate 1
chr1_+_31864404 2.59 ENSDART00000075260
inab
internexin neuronal intermediate filament protein, alpha b
chr25_+_31276842 2.56 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr11_-_24681292 2.53 ENSDART00000089601
olfml3b
olfactomedin-like 3b
chr1_+_45351890 2.45 ENSDART00000145486
si:ch211-243a20.3
si:ch211-243a20.3
chr23_-_21471022 2.36 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr10_-_29903165 2.35 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr23_+_21459263 2.31 ENSDART00000104209
her4.3
hairy-related 4, tandem duplicate 3
chr20_+_23238833 2.30 ENSDART00000074167
ociad2
OCIA domain containing 2
chr25_+_35502552 2.28 ENSDART00000189612
ENSDART00000058443
fibina
fin bud initiation factor a
chr21_-_19006631 2.20 ENSDART00000080269
ENSDART00000191682
pgam2
phosphoglycerate mutase 2 (muscle)
chr4_-_16345227 2.16 ENSDART00000079521
kera
keratocan
chr23_-_21463788 2.07 ENSDART00000079265
her4.4
hairy-related 4, tandem duplicate 4
chr15_+_33989181 2.03 ENSDART00000169487
vwde
von Willebrand factor D and EGF domains
chr10_-_22803740 1.90 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
pcolcea
procollagen C-endopeptidase enhancer a
chr13_+_12045475 1.68 ENSDART00000163053
ENSDART00000160812
ENSDART00000158244
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr18_+_402048 1.64 ENSDART00000166345
gpib
glucose-6-phosphate isomerase b
chr3_-_53486169 1.57 ENSDART00000115243
soul5
heme-binding protein soul5
chr18_+_48423973 1.57 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr8_-_17064243 1.57 ENSDART00000185313
rab3c
RAB3C, member RAS oncogene family
chr20_+_16750177 1.56 ENSDART00000185357
calm1b
calmodulin 1b
chr19_+_32166702 1.53 ENSDART00000021798
fabp11a
fatty acid binding protein 11a
chr7_+_34290051 1.53 ENSDART00000123498
fibinb
fin bud initiation factor b
chr21_-_20341836 1.46 ENSDART00000176689
rbp4l
retinol binding protein 4, like
chr23_-_27857051 1.44 ENSDART00000043462
ENSDART00000137861
acvrl1
activin A receptor like type 1
chr9_-_98982 1.44 ENSDART00000147882
lims2
LIM and senescent cell antigen-like domains 2
chr10_+_21737745 1.41 ENSDART00000170498
ENSDART00000167997
pcdh1g18
protocadherin 1 gamma 18
chr16_-_13595027 1.38 ENSDART00000060004
ntd5
ntl-dependent gene 5
chr16_+_42830152 1.38 ENSDART00000159730
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr20_-_40451115 1.37 ENSDART00000075092
pkib
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr19_+_47311020 1.37 ENSDART00000138295
ext1c
exostoses (multiple) 1c
chr20_-_47704973 1.36 ENSDART00000174808
tfap2b
transcription factor AP-2 beta
chr25_-_15040369 1.33 ENSDART00000159342
ENSDART00000166490
pax6a
paired box 6a
chr10_-_24371312 1.33 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr6_+_22597362 1.32 ENSDART00000131242
cygb2
cytoglobin 2
chr1_-_21409877 1.31 ENSDART00000102782
gria2a
glutamate receptor, ionotropic, AMPA 2a
chr25_-_34632050 1.31 ENSDART00000170671
megf8
multiple EGF-like-domains 8
chr15_-_34567370 1.30 ENSDART00000099793
sostdc1a
sclerostin domain containing 1a
chr24_-_37877743 1.28 ENSDART00000105658
tmem204
transmembrane protein 204
chr19_+_22216778 1.27 ENSDART00000052521
nfatc1
nuclear factor of activated T cells 1
chr21_-_20342096 1.22 ENSDART00000065659
rbp4l
retinol binding protein 4, like
chr19_-_44091405 1.22 ENSDART00000132800
rad21b
RAD21 cohesin complex component b
chr16_+_42829735 1.21 ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr19_-_5699703 1.20 ENSDART00000082050
zgc:174904
zgc:174904
chr17_+_42274825 1.19 ENSDART00000020156
pax1a
paired box 1a
chr3_-_36839115 1.17 ENSDART00000154553
ramp2
receptor (G protein-coupled) activity modifying protein 2
chr2_+_26647472 1.16 ENSDART00000145415
ENSDART00000157409
ttpa
tocopherol (alpha) transfer protein
chr13_-_31452516 1.15 ENSDART00000193268
rtn1a
reticulon 1a
chr20_+_2460864 1.14 ENSDART00000131642
akap7
A kinase (PRKA) anchor protein 7
chr16_-_26676685 1.11 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr4_+_4232562 1.07 ENSDART00000177529
smkr1
small lysine rich protein 1
chr24_-_28243186 1.06 ENSDART00000105691
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr7_+_29133321 1.04 ENSDART00000052346
gnao1b
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr9_-_38587275 1.03 ENSDART00000077446
si:dkey-101k6.5
si:dkey-101k6.5
chr12_-_28881638 0.97 ENSDART00000148459
ENSDART00000039667
ENSDART00000148668
ENSDART00000136593
ENSDART00000139923
ENSDART00000148912
cbx1b
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr9_-_9842149 0.97 ENSDART00000121456
fstl1b
follistatin-like 1b
chr1_-_11973341 0.94 ENSDART00000159981
ENSDART00000066638
grk4
G protein-coupled receptor kinase 4
chr9_-_12424231 0.93 ENSDART00000188952
zgc:162707
zgc:162707
chr6_+_1787160 0.91 ENSDART00000113505
myl9b
myosin, light chain 9b, regulatory
chr9_-_12424791 0.91 ENSDART00000135447
ENSDART00000088199
zgc:162707
zgc:162707
chr18_-_6982499 0.91 ENSDART00000101525
si:dkey-266m15.6
si:dkey-266m15.6
chr10_+_8968203 0.89 ENSDART00000110443
ENSDART00000080772
fstb
follistatin b
chr7_+_17229980 0.87 ENSDART00000184910
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr24_-_982443 0.86 ENSDART00000063151
napga
N-ethylmaleimide-sensitive factor attachment protein, gamma a
chr15_-_14552101 0.86 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr2_+_36646451 0.86 ENSDART00000039174
klhl6
kelch-like family member 6
chr4_+_12612145 0.84 ENSDART00000181201
lmo3
LIM domain only 3
chr19_+_5315987 0.83 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr5_-_39474235 0.81 ENSDART00000171557
antxr2a
anthrax toxin receptor 2a
chr16_+_5579744 0.81 ENSDART00000147973
macf1b
microtubule-actin crosslinking factor 1 b
chr17_+_42274240 0.80 ENSDART00000134377
pax1a
paired box 1a
chr18_-_46241775 0.80 ENSDART00000145999
ENSDART00000134244
ENSDART00000185021
ENSDART00000181855
prx
periaxin
chr23_-_9919959 0.79 ENSDART00000127029
si:ch211-220i18.4
si:ch211-220i18.4
chr6_-_39270851 0.78 ENSDART00000148839
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr16_+_9609721 0.77 ENSDART00000047920
enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr12_+_24344963 0.76 ENSDART00000191648
ENSDART00000183180
ENSDART00000088178
ENSDART00000189696
nrxn1a
neurexin 1a
chr14_+_21106444 0.76 ENSDART00000075744
ENSDART00000132363
aldob
aldolase b, fructose-bisphosphate
chr18_+_17660158 0.75 ENSDART00000186279
cpne2
copine II
chr10_-_15128771 0.74 ENSDART00000101261
spp1
secreted phosphoprotein 1
chr21_-_5879897 0.74 ENSDART00000184034
rpl35
ribosomal protein L35
chr21_-_33995213 0.73 ENSDART00000140184
EBF1 (1 of many)
si:ch211-51e8.2
chr16_+_8716800 0.72 ENSDART00000124693
ENSDART00000181961
cabz01093075.1
cabz01093075.1
chr19_-_22478888 0.70 ENSDART00000090679
pleca
plectin a
chr19_+_19489588 0.70 ENSDART00000166755
tril
TLR4 interactor with leucine-rich repeats
chr20_+_6590220 0.70 ENSDART00000136567
tns3.2
tensin 3, tandem duplicate 2
chr4_+_9609905 0.69 ENSDART00000142284
ENSDART00000150687
meig1
meiosis/spermiogenesis associated 1
chr9_-_44983666 0.69 ENSDART00000149704
itgb2
integrin, beta 2
chr19_-_24267823 0.68 ENSDART00000132430
s100v2
S100 calcium binding protein V2
chr13_-_13294847 0.67 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr19_+_24882845 0.67 ENSDART00000010580
si:ch211-195b13.1
si:ch211-195b13.1
chr24_-_28245872 0.66 ENSDART00000167861
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr10_+_7102461 0.66 ENSDART00000187539
psd3l
pleckstrin and Sec7 domain containing 3, like
chr4_+_12612723 0.66 ENSDART00000133767
lmo3
LIM domain only 3
chr17_+_29345606 0.65 ENSDART00000086164
kctd3
potassium channel tetramerization domain containing 3
chr7_-_2090594 0.62 ENSDART00000183166
si:cabz01007802.1
si:cabz01007802.1
chr13_+_18545819 0.62 ENSDART00000101859
ENSDART00000110197
ENSDART00000136064
zgc:154058
zgc:154058
chr5_-_31904562 0.61 ENSDART00000140640
coro1cb
coronin, actin binding protein, 1Cb
chr5_-_22082918 0.61 ENSDART00000020908
zc4h2
zinc finger, C4H2 domain containing
chr19_-_35596207 0.61 ENSDART00000136811
col8a2
collagen, type VIII, alpha 2
chr11_+_10548171 0.60 ENSDART00000191497
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr15_-_30816370 0.60 ENSDART00000142982
ENSDART00000050649
ENSDART00000136901
ENSDART00000100194
msi2b
musashi RNA-binding protein 2b
chr16_+_54875530 0.60 ENSDART00000149795
nr0b2a
nuclear receptor subfamily 0, group B, member 2a
chr23_+_19977120 0.60 ENSDART00000089342
cfap126
cilia and flagella associated protein 126
chr24_-_37877554 0.59 ENSDART00000132219
tmem204
transmembrane protein 204
chr7_-_25895189 0.58 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr21_+_18313152 0.58 ENSDART00000170510
si:ch73-287m6.1
si:ch73-287m6.1
chr6_-_13408680 0.58 ENSDART00000151566
fmnl2b
formin-like 2b
chr8_+_38417461 0.57 ENSDART00000132718
nkx6.3
NK6 homeobox 3
chr10_-_11761927 0.57 ENSDART00000138748
adamts6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr3_+_17537352 0.56 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr7_+_17229282 0.56 ENSDART00000097982
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr5_-_23429228 0.53 ENSDART00000049291
gria3a
glutamate receptor, ionotropic, AMPA 3a
chr13_+_25422009 0.53 ENSDART00000057686
calhm2
calcium homeostasis modulator 2
chr3_-_32596394 0.53 ENSDART00000103239
tspan4b
tetraspanin 4b
chr12_-_34716037 0.52 ENSDART00000152876
bahcc1b
BAH domain and coiled-coil containing 1b
chr12_+_13652747 0.52 ENSDART00000066359
oplah
5-oxoprolinase, ATP-hydrolysing
chr18_+_17660402 0.51 ENSDART00000143475
cpne2
copine II
chr20_+_50852356 0.50 ENSDART00000167517
ENSDART00000168396
gphnb
gephyrin b
chr15_-_8517376 0.50 ENSDART00000186289
npas1
neuronal PAS domain protein 1
chr9_+_33009284 0.50 ENSDART00000036926
vangl1
VANGL planar cell polarity protein 1
chr8_-_25247284 0.48 ENSDART00000132697
gnat2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr6_+_51824596 0.47 ENSDART00000149003
rspo4
R-spondin 4
chr17_+_38255105 0.46 ENSDART00000005296
nkx2.9
NK2 transcription factor related, locus 9 (Drosophila)
chr6_+_612330 0.46 ENSDART00000166872
ENSDART00000191758
kynu
kynureninase
chr8_+_7033049 0.46 ENSDART00000064172
ENSDART00000134440
gpd1a
glycerol-3-phosphate dehydrogenase 1a
chr7_-_38612230 0.46 ENSDART00000173678
c1qtnf4
C1q and TNF related 4
chr3_-_39363065 0.45 ENSDART00000155894
arhgap23a
Rho GTPase activating protein 23a
chr12_-_7806007 0.44 ENSDART00000190359
ank3b
ankyrin 3b
chr5_-_52752514 0.43 ENSDART00000190162
fam189a2
family with sequence similarity 189, member A2
chr20_+_47434709 0.41 ENSDART00000067776
rab10
RAB10, member RAS oncogene family
chr10_+_40836378 0.41 ENSDART00000085792
trim69
tripartite motif containing 69
chr20_-_20932760 0.41 ENSDART00000152415
ENSDART00000039907
btbd6b
BTB (POZ) domain containing 6b
chr3_-_3731563 0.40 ENSDART00000180978
BX908804.2

chr23_+_26079467 0.40 ENSDART00000129617
atp6ap1b
ATPase H+ transporting accessory protein 1b
chr2_+_5793908 0.40 ENSDART00000145219
slc35d1b
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1b
chr16_+_21738194 0.40 ENSDART00000163688
FP085428.1
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr25_+_15841670 0.40 ENSDART00000049992
syt9b
synaptotagmin IXb
chr3_-_54669185 0.40 ENSDART00000053106
s1pr2
sphingosine-1-phosphate receptor 2
chr2_-_51634431 0.39 ENSDART00000165568
pigr
polymeric immunoglobulin receptor
chr16_-_17300030 0.39 ENSDART00000149267
kel
Kell blood group, metallo-endopeptidase
chr10_+_28587446 0.39 ENSDART00000030138
ENSDART00000137508
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr20_-_13673566 0.39 ENSDART00000181641
TAGAP
si:ch211-122h15.4
chr2_-_37043540 0.38 ENSDART00000131834
gng7
guanine nucleotide binding protein (G protein), gamma 7
chr4_-_71110826 0.37 ENSDART00000167431
si:dkeyp-80d11.1
si:dkeyp-80d11.1
chr2_+_11685742 0.36 ENSDART00000138562
greb1l
growth regulation by estrogen in breast cancer-like
chr2_+_31671545 0.36 ENSDART00000145446
ackr4a
atypical chemokine receptor 4a
chr10_+_20070178 0.35 ENSDART00000027612
ENSDART00000145264
ENSDART00000172713
xpo7
exportin 7
chr22_-_5933844 0.34 ENSDART00000163370
ENSDART00000189331
si:rp71-36a1.2
si:rp71-36a1.2
chr13_+_25421531 0.34 ENSDART00000158093
calhm2
calcium homeostasis modulator 2
chr6_-_50704689 0.33 ENSDART00000074100
osgn1
oxidative stress induced growth inhibitor 1
chr1_+_157793 0.32 ENSDART00000152205
cul4a
cullin 4A
chr24_+_41610068 0.32 ENSDART00000159507
CABZ01044108.1

chr3_+_44947355 0.32 ENSDART00000083040
hs3st2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr4_-_9609634 0.31 ENSDART00000067188
dclre1c
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr19_+_27339848 0.30 ENSDART00000052355
ddx39b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr4_-_1015896 0.30 ENSDART00000170292
FAM180A
family with sequence similarity 180 member A
chr5_+_19314574 0.30 ENSDART00000133247
rusc2
RUN and SH3 domain containing 2
chr19_+_47299212 0.30 ENSDART00000158262
tpmt.1
thiopurine S-methyltransferase, tandem duplicate 1
chr4_-_49827366 0.29 ENSDART00000183761
si:dkey-156k2.3
si:dkey-156k2.3
chr20_-_8443425 0.29 ENSDART00000083908
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr7_-_71837213 0.29 ENSDART00000168645
ENSDART00000160512
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr6_-_36182115 0.27 ENSDART00000154639
brinp3a.2
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 2
chr12_+_20699534 0.27 ENSDART00000131883
si:ch211-119c20.2
si:ch211-119c20.2
chr9_+_7456076 0.26 ENSDART00000125824
ENSDART00000122526
tmem198a
transmembrane protein 198a
chr24_-_1303553 0.26 ENSDART00000190984
nrp1a
neuropilin 1a
chr6_-_10320676 0.26 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr2_-_37043905 0.26 ENSDART00000056514
gng7
guanine nucleotide binding protein (G protein), gamma 7
chr7_+_5494565 0.26 ENSDART00000135271
MYADM
si:dkeyp-67a8.2
chr3_+_17846890 0.26 ENSDART00000193384
znf385c
zinc finger protein 385C
chr21_-_20381481 0.26 ENSDART00000115236
atp5mea
ATP synthase membrane subunit ea
chr5_-_19861766 0.25 ENSDART00000088904
gltpa
glycolipid transfer protein a
chr7_-_56606752 0.23 ENSDART00000138714
sult5a1
sulfotransferase family 5A, member 1
chr5_+_19309877 0.23 ENSDART00000190338
rusc2
RUN and SH3 domain containing 2
chr8_-_29706882 0.23 ENSDART00000045909
prf1.5
perforin 1.5
chr17_-_30839338 0.23 ENSDART00000139707
gdf7
growth differentiation factor 7
chr11_-_37411492 0.22 ENSDART00000166468
erc2
ELKS/RAB6-interacting/CAST family member 2
chr3_+_33367954 0.22 ENSDART00000103161
mpp2a
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr18_-_21097663 0.22 ENSDART00000060196
anpepa
alanyl (membrane) aminopeptidase a
chr5_+_30741730 0.22 ENSDART00000098246
ENSDART00000186992
ENSDART00000182533
ftr83
finTRIM family, member 83
chr25_-_19661198 0.21 ENSDART00000149641
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr22_-_6884981 0.21 ENSDART00000124219
FO904898.4

chr9_+_22764235 0.20 ENSDART00000090875
tnfaip6
tumor necrosis factor, alpha-induced protein 6
chr3_+_15296824 0.19 ENSDART00000043801
cabp5b
calcium binding protein 5b
chr13_-_33170733 0.19 ENSDART00000057382
fbln5
fibulin 5
chr3_+_19732173 0.18 ENSDART00000178684
mrc2
mannose receptor, C type 2
chr9_+_29603649 0.17 ENSDART00000140477
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr7_-_41403022 0.17 ENSDART00000174285
BX322787.1

chr20_-_38446891 0.16 ENSDART00000192013
itpkb
inositol-trisphosphate 3-kinase B
chr16_+_2843428 0.16 ENSDART00000149485
clec3ba
C-type lectin domain family 3, member Ba
chr23_-_452365 0.16 ENSDART00000146776
tspan2b
tetraspanin 2b
chr14_+_48964628 0.16 ENSDART00000105427
mif
macrophage migration inhibitory factor
chr20_-_9278252 0.15 ENSDART00000136079
syt14b
synaptotagmin XIVb
chr24_+_34113424 0.15 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr22_-_8692305 0.15 ENSDART00000181602
CR450686.4

chr24_-_1303935 0.15 ENSDART00000159212
ENSDART00000159267
ENSDART00000164904
nrp1a
neuropilin 1a
chr13_-_25198025 0.14 ENSDART00000159585
ENSDART00000144227
adka
adenosine kinase a
chr20_-_14875308 0.14 ENSDART00000141290
dnm3a
dynamin 3a

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb18+zbtb42

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.4 1.4 GO:0034405 response to fluid shear stress(GO:0034405)
0.2 0.9 GO:0044068 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.2 1.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.2 1.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 1.4 GO:0043090 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.2 0.5 GO:0072579 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.6 GO:0042755 eating behavior(GO:0042755)
0.1 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) anterior lateral line neuromast hair cell development(GO:0035676)
0.1 1.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.4 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.5 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.8 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.1 5.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.4 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508)
0.1 1.3 GO:0048899 anterior lateral line development(GO:0048899)
0.1 2.1 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.1 0.8 GO:1901998 toxin transport(GO:1901998)
0.1 1.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 2.2 GO:0007520 myoblast fusion(GO:0007520)
0.1 2.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.9 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 1.6 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 1.2 GO:0006775 fat-soluble vitamin metabolic process(GO:0006775)
0.1 0.8 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.3 GO:0015671 oxygen transport(GO:0015671)
0.0 1.0 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 2.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.6 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.5 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 1.4 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.5 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 1.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 1.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.0 2.3 GO:0033333 fin development(GO:0033333)
0.0 1.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522) neuron fate specification(GO:0048665)
0.0 0.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.7 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 1.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.7 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 2.4 GO:0021782 glial cell development(GO:0021782)
0.0 1.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.2 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.2 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 2.2 GO:0007601 visual perception(GO:0007601)
0.0 0.3 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0005883 neurofilament(GO:0005883)
0.3 1.4 GO:0070724 BMP receptor complex(GO:0070724)
0.2 1.2 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 2.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 5.6 GO:0005861 troponin complex(GO:0005861)
0.1 2.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.8 GO:0070938 contractile ring(GO:0070938)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.4 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.1 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 21.4 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.4 2.7 GO:0034632 retinol transporter activity(GO:0034632)
0.3 1.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 1.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 1.0 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 0.6 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 1.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 1.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 0.5 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 1.3 GO:0036122 BMP binding(GO:0036122)
0.1 0.9 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.4 GO:0047690 aspartyltransferase activity(GO:0047690)
0.1 1.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.5 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 2.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.4 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 0.3 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.8 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.4 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 1.2 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.9 GO:0048185 activin binding(GO:0048185)
0.0 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.8 GO:0031267 small GTPase binding(GO:0031267)
0.0 1.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 2.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)
0.0 1.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 8.4 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.2 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 3.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators