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PRJNA195909:zebrafish embryo and larva development

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Results for zfhx3+zfhx3a+zfhx4

Z-value: 0.91

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Transcription factors associated with zfhx3+zfhx3a+zfhx4

Gene Symbol Gene ID Gene Info
zfhx3a
ENSDARG00000073944 si_ch73-386h18.1
zfhx4
ENSDARG00000075542 zinc finger homeobox 4
zfhx3
ENSDARG00000103057 zinc finger homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:ch73-386h18.1dr11_v1_chr18_+_6054816_6054816-0.872.3e-03Click!
zfhx4dr11_v1_chr24_-_23323526_23323526-0.751.9e-02Click!
zfhx3dr11_v1_chr7_-_68373495_68373495-0.722.7e-02Click!

Activity profile of zfhx3+zfhx3a+zfhx4 motif

Sorted Z-values of zfhx3+zfhx3a+zfhx4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_38299385 1.57 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr25_+_34915762 1.42 ENSDART00000191776
sntb2
syntrophin, beta 2
chr22_+_14836291 1.30 ENSDART00000122740
gtpbp1l
GTP binding protein 1, like
chr15_+_38299563 1.27 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr15_+_29472065 1.23 ENSDART00000154343
gdpd5b
glycerophosphodiester phosphodiesterase domain containing 5b
chr22_-_24791505 1.19 ENSDART00000136837
vtg4
vitellogenin 4
chr21_-_13123176 1.16 ENSDART00000144866
ENSDART00000024616
fam219aa
family with sequence similarity 219, member Aa
chr23_+_24589633 1.14 ENSDART00000143694
mlh3
mutL homolog 3 (E. coli)
chr16_-_27566552 1.13 ENSDART00000142102
zgc:153215
zgc:153215
chr8_-_20230559 1.13 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr22_+_15960514 1.11 ENSDART00000181617
stil
scl/tal1 interrupting locus
chr9_+_45227028 1.08 ENSDART00000185579
adarb1b
adenosine deaminase, RNA-specific, B1b
chr25_+_28679672 1.06 ENSDART00000139965
ENSDART00000134072
cnot2
CCR4-NOT transcription complex, subunit 2
chr9_-_14143370 1.00 ENSDART00000108950
ttll4
tubulin tyrosine ligase-like family, member 4
chr8_+_10339869 0.98 ENSDART00000132253
tbc1d22b
TBC1 domain family, member 22B
chr19_-_3056235 0.97 ENSDART00000137020
bop1
block of proliferation 1
chr12_+_46582727 0.95 ENSDART00000149326
ush1gb
Usher syndrome 1Gb (autosomal recessive)
chr13_+_25286538 0.95 ENSDART00000180282
chuk
conserved helix-loop-helix ubiquitous kinase
chr22_+_15960005 0.93 ENSDART00000033617
stil
scl/tal1 interrupting locus
chr5_-_34875858 0.89 ENSDART00000085086
arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr22_+_15959844 0.87 ENSDART00000182201
stil
scl/tal1 interrupting locus
chr5_+_19933356 0.86 ENSDART00000088819
ankrd13a
ankyrin repeat domain 13A
chr19_+_2631565 0.85 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr8_-_20230802 0.85 ENSDART00000063400
mllt1a
MLLT1, super elongation complex subunit a
chr12_+_27061720 0.82 ENSDART00000153426
srcap
Snf2-related CREBBP activator protein
chr12_+_30788912 0.81 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr18_+_7611298 0.81 ENSDART00000062156
odf3b
outer dense fiber of sperm tails 3B
chr22_-_24818066 0.79 ENSDART00000143443
vtg6
vitellogenin 6
chr6_-_43283122 0.78 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr11_+_24804556 0.77 ENSDART00000082761
ENSDART00000186283
adipor1a
adiponectin receptor 1a
chr5_-_19932621 0.77 ENSDART00000088881
git2a
G protein-coupled receptor kinase interacting ArfGAP 2a
chr18_+_16053455 0.77 ENSDART00000189163
ENSDART00000188269
FO834850.1

chr8_-_25569920 0.75 ENSDART00000136869
prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr5_+_9224051 0.74 ENSDART00000139265
si:ch211-12e13.12
si:ch211-12e13.12
chr17_-_51893123 0.74 ENSDART00000103350
ENSDART00000017329
numb
numb homolog (Drosophila)
chr10_+_8197827 0.71 ENSDART00000026244
mtrex
Mtr4 exosome RNA helicase
chr24_-_2450597 0.70 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr5_+_6954162 0.70 ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr20_-_40754794 0.68 ENSDART00000187251
cx32.3
connexin 32.3
chr13_+_31205439 0.68 ENSDART00000132326
ptpn20
protein tyrosine phosphatase, non-receptor type 20
chr23_+_45200481 0.66 ENSDART00000004357
ENSDART00000111126
ENSDART00000193560
ENSDART00000190476
psip1b
PC4 and SFRS1 interacting protein 1b
chr16_-_41787421 0.65 ENSDART00000147210
si:dkey-199f5.8
si:dkey-199f5.8
chr13_+_45524475 0.63 ENSDART00000074567
ENSDART00000019113
maco1b
macoilin 1b
chr20_+_31076488 0.61 ENSDART00000136255
ENSDART00000008840
otofa
otoferlin a
chr10_-_11261565 0.59 ENSDART00000146727
ptbp3
polypyrimidine tract binding protein 3
chr22_-_34551568 0.58 ENSDART00000148147
rnf123
ring finger protein 123
chr20_+_36629173 0.57 ENSDART00000161241
ephx1
epoxide hydrolase 1, microsomal (xenobiotic)
chr3_-_20040636 0.57 ENSDART00000104118
atxn7l3
ataxin 7-like 3
chr1_+_22851261 0.57 ENSDART00000193925
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr16_-_55259199 0.53 ENSDART00000161130
iqgap3
IQ motif containing GTPase activating protein 3
chr12_+_47081783 0.53 ENSDART00000158568
mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr16_-_44127307 0.52 ENSDART00000104583
ENSDART00000151936
ENSDART00000058685
ENSDART00000190830
zfpm2a
zinc finger protein, FOG family member 2a
chr21_+_37513488 0.51 ENSDART00000185394
amot
angiomotin
chr12_-_18578218 0.51 ENSDART00000125803
zdhhc4
zinc finger, DHHC-type containing 4
chr25_+_34915576 0.50 ENSDART00000073441
sntb2
syntrophin, beta 2
chr16_-_31351419 0.50 ENSDART00000178298
ENSDART00000018091
mroh1
maestro heat-like repeat family member 1
chr20_+_30610547 0.50 ENSDART00000122256
ccr6a
chemokine (C-C motif) receptor 6a
chr2_+_29249561 0.49 ENSDART00000099157
cdh18a
cadherin 18, type 2a
chr15_-_3534705 0.48 ENSDART00000158150
cog6
component of oligomeric golgi complex 6
chr12_-_18578432 0.46 ENSDART00000122858
zdhhc4
zinc finger, DHHC-type containing 4
chr10_-_8197049 0.45 ENSDART00000129467
dhx29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr5_+_13394543 0.45 ENSDART00000051669
ENSDART00000135921
tctn2
tectonic family member 2
chr17_+_8799451 0.45 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr19_+_3056450 0.44 ENSDART00000141324
ENSDART00000082353
hsf1
heat shock transcription factor 1
chr21_-_39177564 0.44 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr20_+_27298783 0.42 ENSDART00000013861
ppp4r4
protein phosphatase 4, regulatory subunit 4
chr10_-_11261386 0.40 ENSDART00000189946
ptbp3
polypyrimidine tract binding protein 3
chr6_-_48473694 0.40 ENSDART00000154237
ppm1j
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr17_+_8212477 0.39 ENSDART00000064665
slc18b1
solute carrier family 18, subfamily B, member 1
chr24_+_26329018 0.39 ENSDART00000145752
mynn
myoneurin
chr22_+_2751887 0.39 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr3_+_29714775 0.39 ENSDART00000041388
cacng2a
calcium channel, voltage-dependent, gamma subunit 2a
chr5_+_28830388 0.38 ENSDART00000149150
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr8_+_50742975 0.38 ENSDART00000155664
ENSDART00000160612
si:ch73-6l19.2
si:ch73-6l19.2
chr17_-_30975978 0.38 ENSDART00000051697
evla
Enah/Vasp-like a
chr4_-_22338906 0.37 ENSDART00000131402
golgb1
golgin B1
chr23_+_13375359 0.37 ENSDART00000151947
ZNF512B
si:dkey-256k13.2
chr8_+_1839695 0.36 ENSDART00000148254
ENSDART00000143473
snap29
synaptosomal-associated protein 29
chr4_-_27117112 0.36 ENSDART00000034534
zbed4
zinc finger, BED-type containing 4
chr5_-_30620625 0.35 ENSDART00000098273
tcnl
transcobalamin like
chr24_+_26328787 0.35 ENSDART00000003884
mynn
myoneurin
chr16_+_24733741 0.34 ENSDART00000155217
si:dkey-79d12.4
si:dkey-79d12.4
chr18_-_17399291 0.32 ENSDART00000192075
ENSDART00000060949
ENSDART00000188506
zfpm1
zinc finger protein, FOG family member 1
chr2_-_30784198 0.32 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr5_+_28848870 0.32 ENSDART00000149563
zgc:174259
zgc:174259
chr5_+_28849155 0.31 ENSDART00000079090
zgc:174259
zgc:174259
chr17_-_24820801 0.31 ENSDART00000156606
trmt61b
tRNA methyltransferase 61B
chr1_+_26480890 0.30 ENSDART00000164430
uso1
USO1 vesicle transport factor
chr6_-_43498996 0.30 ENSDART00000154742
MDFIC2
si:dkey-58f6.2
chr12_-_28848015 0.30 ENSDART00000153200
si:ch211-194k22.8
si:ch211-194k22.8
chr20_+_41756996 0.29 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr20_+_19423823 0.29 ENSDART00000152216
znf513a
zinc finger protein 513a
chr5_+_4054704 0.29 ENSDART00000140537
dhrs11a
dehydrogenase/reductase (SDR family) member 11a
chr11_+_7432533 0.28 ENSDART00000180977
adgrl2a
adhesion G protein-coupled receptor L2a
chr6_-_29515709 0.27 ENSDART00000180205
pex5la
peroxisomal biogenesis factor 5-like a
chr5_+_28858345 0.27 ENSDART00000111180
si:ch211-186e20.2
si:ch211-186e20.2
chr18_+_2228737 0.26 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr20_+_45620076 0.26 ENSDART00000113806
hnrnpa0l
heterogeneous nuclear ribonucleoprotein A0, like
chr16_-_25608453 0.26 ENSDART00000140140
zgc:110410
zgc:110410
chr17_+_8799661 0.24 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr9_+_12444494 0.23 ENSDART00000102430
tmem41aa
transmembrane protein 41aa
chr5_+_28830643 0.21 ENSDART00000051448
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr3_-_5228137 0.21 ENSDART00000137105
myh9b
myosin, heavy chain 9b, non-muscle
chr23_-_29394505 0.21 ENSDART00000017728
pgd
phosphogluconate dehydrogenase
chr3_-_31715714 0.20 ENSDART00000051542
ccdc47
coiled-coil domain containing 47
chr25_+_29474583 0.20 ENSDART00000191189
il17rel
interleukin 17 receptor E-like
chr1_+_33558555 0.20 ENSDART00000018472
chmp2bb
charged multivesicular body protein 2Bb
chr2_+_29249204 0.19 ENSDART00000168957
cdh18a
cadherin 18, type 2a
chr14_-_7207961 0.19 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr23_-_41965557 0.18 ENSDART00000144183
slc1a7b
solute carrier family 1 (glutamate transporter), member 7b
chr22_-_38480186 0.16 ENSDART00000171704
soul4
heme-binding protein soul4
chr14_+_2487672 0.15 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr1_+_44003654 0.15 ENSDART00000131337
si:dkey-22i16.10
si:dkey-22i16.10
chr11_+_29770966 0.14 ENSDART00000088624
ENSDART00000124471
rpgrb
retinitis pigmentosa GTPase regulator b
chr14_+_8594367 0.14 ENSDART00000037749
stx5a
syntaxin 5A
chr1_-_15797663 0.13 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr7_-_20865005 0.12 ENSDART00000190752
fis1
fission, mitochondrial 1
chr2_-_7845110 0.12 ENSDART00000091987
si:ch211-38m6.7
si:ch211-38m6.7
chr1_+_44838706 0.12 ENSDART00000162779
ENSDART00000147357
kdm2aa
lysine (K)-specific demethylase 2Aa
chr18_+_15644559 0.10 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr7_-_17443332 0.08 ENSDART00000182348
nitr3c
novel immune-type receptor 3c
chr17_+_9310259 0.08 ENSDART00000186158
ENSDART00000190329
NPAS3
neuronal PAS domain protein 3
chr10_+_11261576 0.07 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr2_-_27609189 0.06 ENSDART00000040555
lyn
LYN proto-oncogene, Src family tyrosine kinase
chr18_-_22713621 0.06 ENSDART00000079013
si:ch73-113g13.2
si:ch73-113g13.2
chr10_-_42131408 0.06 ENSDART00000076693
stambpa
STAM binding protein a
chr15_+_35139457 0.05 ENSDART00000059204
slc19a3a
solute carrier family 19 (thiamine transporter), member 3a
chr10_-_17179415 0.05 ENSDART00000131751
depdc5
DEP domain containing 5
chr20_-_40750953 0.05 ENSDART00000061256
cx28.9
connexin 28.9
chr22_-_294700 0.05 ENSDART00000189179
CABZ01079179.1

chr14_+_10596628 0.03 ENSDART00000115177
gpr174
G protein-coupled receptor 174
chr14_-_25111496 0.03 ENSDART00000158108
si:rp71-1d10.8
si:rp71-1d10.8
chr17_-_7371564 0.02 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr18_-_22713402 0.02 ENSDART00000145871
si:ch73-113g13.2
si:ch73-113g13.2
chr17_+_2162916 0.02 ENSDART00000103775
pak6a
p21 protein (Cdc42/Rac)-activated kinase 6a
chr23_+_20689255 0.01 ENSDART00000182420
usp21
ubiquitin specific peptidase 21
chr18_+_29950233 0.01 ENSDART00000146431
atmin
ATM interactor
chr21_+_13150937 0.01 ENSDART00000102251
sptan1
spectrin alpha, non-erythrocytic 1
chr17_+_31914877 0.01 ENSDART00000177801
FAM196A (1 of many)
family with sequence similarity 196 member A
chr22_+_19220459 0.00 ENSDART00000163070
si:dkey-21e2.7
si:dkey-21e2.7

Network of associatons between targets according to the STRING database.

First level regulatory network of zfhx3+zfhx3a+zfhx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 1.0 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.6 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 1.1 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 1.0 GO:0050957 equilibrioception(GO:0050957)
0.1 0.8 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 1.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.3 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.6 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.3 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 0.3 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.5 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 2.0 GO:0032355 response to estradiol(GO:0032355)
0.1 0.4 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 1.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.4 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.1 GO:0006298 mismatch repair(GO:0006298)
0.0 0.4 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.5 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.8 GO:0043486 histone exchange(GO:0043486)
0.0 0.7 GO:0031297 replication fork processing(GO:0031297)
0.0 0.3 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 1.0 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.4 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.1 GO:0043653 peroxisome fission(GO:0016559) mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.7 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0009408 response to heat(GO:0009408)
0.0 1.2 GO:0003401 axis elongation(GO:0003401)
0.0 0.6 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.8 GO:0006414 translational elongation(GO:0006414)
0.0 1.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0007530 sex determination(GO:0007530)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070545 PeBoW complex(GO:0070545)
0.2 1.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.1 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.6 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.9 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.8 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.3 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 2.9 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 1.3 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0045735 nutrient reservoir activity(GO:0045735)
0.2 1.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 0.6 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.2 0.8 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.0 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.3 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.7 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.4 GO:0045296 cadherin binding(GO:0045296)
0.0 1.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing