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PRJNA195909:zebrafish embryo and larva development

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Results for znf711

Z-value: 2.19

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Transcription factors associated with znf711

Gene Symbol Gene ID Gene Info
znf711
ENSDARG00000071868 Danio rerio zinc finger protein 711 (znf711), transcript variant 1, mRNA.
znf711
ENSDARG00000111963 zinc finger protein 711

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf711dr11_v1_chr14_-_12020653_120206530.862.6e-03Click!

Activity profile of znf711 motif

Sorted Z-values of znf711 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_27830818 3.11 ENSDART00000131767
papd7
PAP associated domain containing 7
chr20_-_43742822 3.04 ENSDART00000181729
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr23_+_35650771 2.96 ENSDART00000005158
ccnt1
cyclin T1
chr17_+_654759 2.95 ENSDART00000193703
CABZ01079748.1

chr19_+_31585917 2.89 ENSDART00000132182
gmnn
geminin, DNA replication inhibitor
chr20_+_1329509 2.74 ENSDART00000017791
ENSDART00000136669
tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr3_+_18807524 2.67 ENSDART00000055757
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr19_+_31585341 2.65 ENSDART00000052185
gmnn
geminin, DNA replication inhibitor
chr8_+_52377516 2.52 ENSDART00000115398
arid5a
AT rich interactive domain 5A (MRF1-like)
chr5_+_55984270 2.48 ENSDART00000047358
ENSDART00000138191
fkbp6
FK506 binding protein 6
chr2_+_23007675 2.30 ENSDART00000163649
mknk2a
MAP kinase interacting serine/threonine kinase 2a
chr7_-_24838857 2.29 ENSDART00000179766
ENSDART00000180892
fam113
family with sequence similarity 113
chr2_+_24936766 2.28 ENSDART00000025962
gyg1a
glycogenin 1a
chr7_+_44802353 2.27 ENSDART00000066380
ca7
carbonic anhydrase VII
chr2_-_57469115 2.26 ENSDART00000192201
pias4b
protein inhibitor of activated STAT, 4b
chr2_-_48255843 2.23 ENSDART00000056277
gigyf2
GRB10 interacting GYF protein 2
chr16_+_25066880 2.09 ENSDART00000154084
im:7147486
im:7147486
chr16_-_46578523 2.04 ENSDART00000131061
si:dkey-152b24.6
si:dkey-152b24.6
chr8_+_10869183 2.00 ENSDART00000188111
brpf3b
bromodomain and PHD finger containing, 3b
chr16_+_25163443 1.97 ENSDART00000105514
znf576.2
zinc finger protein 576, tandem duplicate 2
chr14_+_31493306 1.96 ENSDART00000138341
phf6
PHD finger protein 6
chr22_+_14836291 1.90 ENSDART00000122740
gtpbp1l
GTP binding protein 1, like
chr2_+_22659787 1.83 ENSDART00000043956
zgc:161973
zgc:161973
chr3_-_31619463 1.81 ENSDART00000124559
moto
minamoto
chr3_+_17653784 1.80 ENSDART00000159984
ENSDART00000157682
ENSDART00000187937
kat2a
K(lysine) acetyltransferase 2A
chr15_+_39977461 1.80 ENSDART00000063786
cab39
calcium binding protein 39
chr20_-_24183333 1.80 ENSDART00000025862
ENSDART00000153075
map3k7
mitogen-activated protein kinase kinase kinase 7
chr3_+_19685873 1.75 ENSDART00000006490
tlk2
tousled-like kinase 2
chr5_-_16472719 1.72 ENSDART00000162071
piwil2
piwi-like RNA-mediated gene silencing 2
chr20_+_33924235 1.70 ENSDART00000146292
ENSDART00000139609
lmx1a
LIM homeobox transcription factor 1, alpha
chr1_+_10129099 1.70 ENSDART00000187740
rbm46
RNA binding motif protein 46
chr25_-_32869794 1.69 ENSDART00000162784
tmem266
transmembrane protein 266
chr6_-_54348568 1.69 ENSDART00000156501
zgc:101577
zgc:101577
chr3_+_32410746 1.63 ENSDART00000025496
rras
RAS related
chr18_-_21047007 1.56 ENSDART00000162702
igf1ra
insulin-like growth factor 1a receptor
chr8_+_25733872 1.56 ENSDART00000156340
si:ch211-167b20.8
si:ch211-167b20.8
chr23_-_20010579 1.55 ENSDART00000089999
b4galt3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr12_-_1034383 1.53 ENSDART00000152455
ENSDART00000152346
polr3e
polymerase (RNA) III (DNA directed) polypeptide E
chr3_-_26190804 1.52 ENSDART00000136001
ypel3
yippee-like 3
chr14_+_31493119 1.50 ENSDART00000006463
phf6
PHD finger protein 6
chr11_+_6010177 1.50 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
gtpbp3
GTP binding protein 3, mitochondrial
chr2_+_44512324 1.49 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
pask
PAS domain containing serine/threonine kinase
chr16_-_31621719 1.43 ENSDART00000176939
phf20l1
PHD finger protein 20 like 1
chr13_+_11829072 1.43 ENSDART00000079356
ENSDART00000170160
sufu
suppressor of fused homolog (Drosophila)
chr9_-_25366541 1.42 ENSDART00000021672
epc2
enhancer of polycomb homolog 2 (Drosophila)
chr7_+_5976613 1.41 ENSDART00000173105
si:dkey-23a13.21
si:dkey-23a13.21
chr18_-_21748808 1.41 ENSDART00000079253
pskh1
protein serine kinase H1
chr10_-_35186310 1.41 ENSDART00000127805
pom121
POM121 transmembrane nucleoporin
chr14_+_31509922 1.41 ENSDART00000124499
hprt1
hypoxanthine phosphoribosyltransferase 1
chr18_+_2153530 1.40 ENSDART00000158255
pygo1
pygopus family PHD finger 1
chr16_+_20055878 1.38 ENSDART00000146436
ankrd28b
ankyrin repeat domain 28b
chr5_-_18007077 1.38 ENSDART00000129878
zdhhc8b
zinc finger, DHHC-type containing 8b
chr11_-_9948487 1.37 ENSDART00000189677
ENSDART00000113171
nlgn1
neuroligin 1
chr18_+_15271993 1.37 ENSDART00000099777
si:dkey-103i16.6
si:dkey-103i16.6
chr13_+_45524475 1.37 ENSDART00000074567
ENSDART00000019113
maco1b
macoilin 1b
chr24_+_17005647 1.36 ENSDART00000149149
zfx
zinc finger protein, X-linked
chr3_-_40202607 1.36 ENSDART00000074757
znf598
zinc finger protein 598
chr9_+_21306902 1.35 ENSDART00000138554
ENSDART00000004108
xpo4
exportin 4
chr13_+_15657911 1.35 ENSDART00000134972
ENSDART00000138991
ENSDART00000133342
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr24_-_20641000 1.34 ENSDART00000166135
zbtb47b
zinc finger and BTB domain containing 47b
chr4_-_5831036 1.33 ENSDART00000166232
foxm1
forkhead box M1
chr7_+_40081630 1.33 ENSDART00000173559
zgc:112356
zgc:112356
chr1_+_8521323 1.32 ENSDART00000121439
ENSDART00000103626
ENSDART00000141283
mief2
mitochondrial elongation factor 2
chr13_+_2357637 1.32 ENSDART00000017148
gclc
glutamate-cysteine ligase, catalytic subunit
chr6_+_18418651 1.31 ENSDART00000171097
ENSDART00000167798
rab11fip4b
RAB11 family interacting protein 4 (class II) b
chr25_+_36349574 1.31 ENSDART00000184101
zgc:173552
zgc:173552
chr1_-_23370395 1.30 ENSDART00000143014
ENSDART00000126785
ENSDART00000159138
pds5a
PDS5 cohesin associated factor A
chr8_-_25600888 1.30 ENSDART00000193860
stk38a
serine/threonine kinase 38a
chr9_-_39624173 1.29 ENSDART00000180106
ENSDART00000126766
erbb4b
erb-b2 receptor tyrosine kinase 4b
chr1_-_8928841 1.29 ENSDART00000103652
grin2ab
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr25_+_26901149 1.27 ENSDART00000153839
znf800a
zinc finger protein 800a
chr12_+_36428052 1.27 ENSDART00000131300
unk
unkempt family zinc finger
chr5_+_63329608 1.27 ENSDART00000139180
si:ch73-376l24.3
si:ch73-376l24.3
chr5_+_13326765 1.27 ENSDART00000090851
ydjc
YdjC chitooligosaccharide deacetylase homolog
chr20_-_1268863 1.27 ENSDART00000109321
ENSDART00000027119
lats1
large tumor suppressor kinase 1
chr16_+_20056030 1.27 ENSDART00000027020
ankrd28b
ankyrin repeat domain 28b
chr3_-_10634438 1.27 ENSDART00000093037
ENSDART00000130761
ENSDART00000156617
map2k4a
mitogen-activated protein kinase kinase 4a
chr11_-_25853212 1.26 ENSDART00000145655
tmem51b
transmembrane protein 51b
chr1_-_54972170 1.25 ENSDART00000150548
ENSDART00000038330
khsrp
KH-type splicing regulatory protein
chr18_+_44631789 1.25 ENSDART00000144271
bicra
BRD4 interacting chromatin remodeling complex associated protein
chr20_+_20751425 1.24 ENSDART00000177048
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr18_-_15610856 1.24 ENSDART00000099849
arntl2
aryl hydrocarbon receptor nuclear translocator-like 2
chr7_-_6438544 1.23 ENSDART00000173180
zgc:165555
zgc:165555
chr11_-_45470370 1.21 ENSDART00000173098
gemin6
gem (nuclear organelle) associated protein 6
chr16_-_39477746 1.19 ENSDART00000102525
stt3b
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr7_+_20260172 1.18 ENSDART00000012450
dvl2
dishevelled segment polarity protein 2
chr3_+_32714157 1.17 ENSDART00000131774
setd1a
SET domain containing 1A
chr24_-_38192003 1.17 ENSDART00000109975
crp7
C-reactive protein 7
chr1_-_54971968 1.17 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr22_-_10752471 1.16 ENSDART00000081191
sass6
SAS-6 centriolar assembly protein
chr5_-_72390259 1.16 ENSDART00000172302
wbp1
WW domain binding protein 1
chr9_+_20554178 1.16 ENSDART00000183911
ENSDART00000147435
man1a2
mannosidase, alpha, class 1A, member 2
chr13_+_14006118 1.14 ENSDART00000131875
ENSDART00000089528
atrn
attractin
chr18_-_17147600 1.14 ENSDART00000141873
zc3h18
zinc finger CCCH-type containing 18
chr21_-_43428040 1.14 ENSDART00000148325
stk26
serine/threonine protein kinase 26
chr15_+_17100697 1.14 ENSDART00000183565
ENSDART00000123197
relb
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr3_-_45245607 1.14 ENSDART00000181003
ENSDART00000193586
usp31
ubiquitin specific peptidase 31
chr15_+_24549054 1.13 ENSDART00000155900
phf12b
PHD finger protein 12b
chr7_+_48297842 1.13 ENSDART00000052123
slc25a44b
solute carrier family 25, member 44 b
chr15_-_17025212 1.13 ENSDART00000014465
hip1
huntingtin interacting protein 1
chr7_+_13491452 1.12 ENSDART00000053535
arih1l
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
chr15_+_1766734 1.12 ENSDART00000168250
cul3b
cullin 3b
chr17_-_5610514 1.11 ENSDART00000004043
enpp4
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr1_+_8508753 1.11 ENSDART00000091683
alkbh5
alkB homolog 5, RNA demethylase
chr2_+_2818645 1.11 ENSDART00000163587
rock1
Rho-associated, coiled-coil containing protein kinase 1
chr3_-_33113879 1.10 ENSDART00000044677
rarab
retinoic acid receptor, alpha b
chr16_-_39477509 1.10 ENSDART00000191330
stt3b
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr11_-_26362294 1.10 ENSDART00000184654
ENSDART00000115037
foxj3
forkhead box J3
chr8_+_36560019 1.10 ENSDART00000136418
ENSDART00000061378
ENSDART00000185237
sf3a1
splicing factor 3a, subunit 1
chr20_-_18535502 1.09 ENSDART00000049437
cdc42bpb
CDC42 binding protein kinase beta (DMPK-like)
chr5_+_59030096 1.09 ENSDART00000179814
ENSDART00000110182
rabep1
rabaptin, RAB GTPase binding effector protein 1
chr7_-_73845736 1.09 ENSDART00000193414
zgc:173552
zgc:173552
chr11_+_2649891 1.09 ENSDART00000093052
si:ch211-160o17.4
si:ch211-160o17.4
chr17_+_22587356 1.09 ENSDART00000157328
birc6
baculoviral IAP repeat containing 6
chr8_+_26372115 1.08 ENSDART00000053460
nat6
N-acetyltransferase 6
chr5_-_23464970 1.08 ENSDART00000141028
si:dkeyp-20g2.1
si:dkeyp-20g2.1
chr20_-_9199721 1.08 ENSDART00000064140
ylpm1
YLP motif containing 1
chr25_-_21280584 1.06 ENSDART00000143644
tmem60
transmembrane protein 60
chr3_+_32411343 1.06 ENSDART00000186287
ENSDART00000141793
rras
RAS related
chr20_+_35085224 1.06 ENSDART00000040456
cdc42bpab
CDC42 binding protein kinase alpha (DMPK-like) b
chr25_-_11026907 1.05 ENSDART00000156846
mespbb
mesoderm posterior bb
chr3_+_32631372 1.04 ENSDART00000129339
srrm2
serine/arginine repetitive matrix 2
chr19_-_46058963 1.04 ENSDART00000170409
nup153
nucleoporin 153
chr1_+_45925365 1.04 ENSDART00000144245
eif5b
eukaryotic translation initiation factor 5B
chr5_-_38384289 1.03 ENSDART00000135260
mink1
misshapen-like kinase 1
chr23_+_28092083 1.03 ENSDART00000053958
c1galt1a
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr14_-_12020653 1.03 ENSDART00000106654
znf711
zinc finger protein 711
chr21_-_18086114 1.02 ENSDART00000143987
vav2
vav 2 guanine nucleotide exchange factor
chr18_-_17147803 1.02 ENSDART00000187986
ENSDART00000169080
zc3h18
zinc finger CCCH-type containing 18
chr22_+_18349794 1.02 ENSDART00000186580
gatad2ab
GATA zinc finger domain containing 2Ab
chr7_-_804515 1.02 ENSDART00000159359
rela
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr20_-_24182689 1.02 ENSDART00000171184
map3k7
mitogen-activated protein kinase kinase kinase 7
chr1_-_49947482 1.02 ENSDART00000143398
sgms2
sphingomyelin synthase 2
chr4_-_9191220 1.02 ENSDART00000156919
hcfc2
host cell factor C2
chr21_-_45871866 1.00 ENSDART00000161716
larp1
La ribonucleoprotein domain family, member 1
chr11_+_5817202 1.00 ENSDART00000126084
ctdspl3
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3
chr4_+_4079418 0.99 ENSDART00000028016
waslb
Wiskott-Aldrich syndrome-like b
chr6_+_32326074 0.99 ENSDART00000042134
ENSDART00000181177
dock7
dedicator of cytokinesis 7
chr19_-_6083761 0.99 ENSDART00000151185
ENSDART00000143941
gsk3aa
glycogen synthase kinase 3 alpha a
chr4_+_9911534 0.98 ENSDART00000109452
sbf1
SET binding factor 1
chr15_-_36249087 0.98 ENSDART00000157190
ostn
osteocrin
chr5_-_25236340 0.98 ENSDART00000162774
abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr20_-_34069956 0.97 ENSDART00000017941
tprb
translocated promoter region b, nuclear basket protein
chr7_+_22747915 0.96 ENSDART00000173609
fxr2
fragile X mental retardation, autosomal homolog 2
chr2_+_3044992 0.96 ENSDART00000020463
zgc:63882
zgc:63882
chr16_-_25680666 0.96 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr7_-_40082053 0.96 ENSDART00000083719
ENSDART00000173687
shrprbck1r
sharpin and rbck1 related
chr1_+_31658011 0.96 ENSDART00000192203
poll
polymerase (DNA directed), lambda
chr10_-_38243579 0.96 ENSDART00000150159
usp25
ubiquitin specific peptidase 25
chr18_+_47301086 0.95 ENSDART00000009775
rbm7
RNA binding motif protein 7
chr6_-_11812224 0.95 ENSDART00000150989
march7
membrane-associated ring finger (C3HC4) 7
chr3_-_15496551 0.94 ENSDART00000124063
ENSDART00000007726
sgf29
SAGA complex associated factor 29
chr1_-_49947290 0.93 ENSDART00000141476
sgms2
sphingomyelin synthase 2
chr6_-_49861506 0.93 ENSDART00000121809
gnas
GNAS complex locus
chr11_-_18017918 0.93 ENSDART00000040171
qrich1
glutamine-rich 1
chr19_-_47832853 0.92 ENSDART00000170988
ago4
argonaute RISC catalytic component 4
chr11_-_891674 0.92 ENSDART00000172904
atg7
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr23_+_39481537 0.91 ENSDART00000187222
mical1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr6_-_9565526 0.91 ENSDART00000151470
map3k2
mitogen-activated protein kinase kinase kinase 2
chr9_+_20554896 0.91 ENSDART00000144248
man1a2
mannosidase, alpha, class 1A, member 2
chr10_-_21941443 0.91 ENSDART00000174954
FO744833.1

chr23_+_43718115 0.90 ENSDART00000149266
ENSDART00000149503
anapc10
anaphase promoting complex subunit 10
chr8_-_31416403 0.90 ENSDART00000098912
znf131
zinc finger protein 131
chr3_-_15496295 0.89 ENSDART00000144369
sgf29
SAGA complex associated factor 29
chr2_+_16798652 0.88 ENSDART00000145778
ENSDART00000087120
eif4g1a
eukaryotic translation initiation factor 4 gamma, 1a
chr7_+_38260434 0.88 ENSDART00000052351
cnep1r1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr3_-_5644028 0.88 ENSDART00000019957
ddx39ab
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
chr11_-_18107447 0.88 ENSDART00000187376
qrich1
glutamine-rich 1
chr14_+_20156477 0.88 ENSDART00000123434
fmr1
fragile X mental retardation 1
chr13_+_11876437 0.87 ENSDART00000179753
trim8a
tripartite motif containing 8a
chr2_-_1622641 0.87 ENSDART00000082143
prkacbb
protein kinase, cAMP-dependent, catalytic, beta b
chr11_-_14102131 0.87 ENSDART00000085158
ENSDART00000191962
tmem259
transmembrane protein 259
chr15_-_4616816 0.86 ENSDART00000160191
ENSDART00000161721
ENSDART00000144949
eif4h
eukaryotic translation initiation factor 4h
chr1_+_45925150 0.86 ENSDART00000074689
eif5b
eukaryotic translation initiation factor 5B
chr2_-_38080075 0.86 ENSDART00000056544
tox4a
TOX high mobility group box family member 4 a
chr20_-_53078607 0.86 ENSDART00000163494
ENSDART00000191730
CABZ01066813.1

chr21_-_27251112 0.85 ENSDART00000137667
mark2a
MAP/microtubule affinity-regulating kinase 2a
chr2_-_37134169 0.85 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
elavl1a
ELAV like RNA binding protein 1a
chr5_-_15851953 0.85 ENSDART00000173101
si:dkey-1k23.3
si:dkey-1k23.3
chr12_-_4632519 0.84 ENSDART00000110514
prr12a
proline rich 12a
chr3_+_27607268 0.84 ENSDART00000024453
usp7
ubiquitin specific peptidase 7 (herpes virus-associated)
chr7_+_5968225 0.83 ENSDART00000083397
zgc:165555
zgc:165555
chr20_+_29209767 0.83 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr3_+_7040363 0.83 ENSDART00000157805
BX000701.2

chr13_+_51710725 0.83 ENSDART00000163741
pwwp2b
PWWP domain containing 2B
chr18_+_41560822 0.83 ENSDART00000158503
baz1b
bromodomain adjacent to zinc finger domain, 1B
chr25_+_9003879 0.83 ENSDART00000186228
rag1
recombination activating gene 1
chr2_-_31800521 0.82 ENSDART00000112763
retreg1
reticulophagy regulator 1
chr5_+_31036911 0.82 ENSDART00000141463
ENSDART00000162121
zzef1
zinc finger, ZZ-type with EF hand domain 1
chr16_+_28270037 0.82 ENSDART00000059035
mindy3
MINDY lysine 48 deubiquitinase 3
chr24_+_21514283 0.81 ENSDART00000007066
cdk8
cyclin-dependent kinase 8
chr16_+_32082359 0.80 ENSDART00000140794
ENSDART00000137029
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast)
chr7_-_49654492 0.79 ENSDART00000174324
hrasb
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr5_-_14443124 0.79 ENSDART00000006622
kat6a
K(lysine) acetyltransferase 6A
chr9_+_6082793 0.79 ENSDART00000192045
st6gal2a
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr1_-_24918686 0.79 ENSDART00000148076
fbxw7
F-box and WD repeat domain containing 7
chr22_-_22242884 0.79 ENSDART00000020937
hdgfl2
HDGF like 2
chr17_+_4325693 0.78 ENSDART00000154264
mcm8
minichromosome maintenance 8 homologous recombination repair factor
chr1_-_55183088 0.78 ENSDART00000100619
LUC7L2
zgc:158803
chr14_-_28568107 0.78 ENSDART00000042850
ENSDART00000145502
insb
preproinsulin b

Network of associatons between targets according to the STRING database.

First level regulatory network of znf711

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.5 1.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.4 1.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.4 1.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.4 1.1 GO:1903392 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.4 1.4 GO:1904590 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.3 1.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 0.9 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.3 0.9 GO:0019417 sulfur oxidation(GO:0019417)
0.3 6.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 1.1 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.3 1.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.3 0.8 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.3 1.8 GO:0007141 male meiosis I(GO:0007141)
0.3 1.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 0.7 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 1.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 2.4 GO:0006611 protein export from nucleus(GO:0006611)
0.2 1.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 0.6 GO:0072592 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.2 0.8 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.2 1.0 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.2 0.6 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.2 2.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 1.0 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 1.5 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 0.9 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 1.1 GO:0003272 endocardial cushion formation(GO:0003272)
0.2 0.5 GO:0046822 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleocytoplasmic transport(GO:0046822) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.2 0.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 3.2 GO:0043687 post-translational protein modification(GO:0043687)
0.2 0.9 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2 1.0 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.2 0.9 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.2 0.7 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 1.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 0.5 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.2 1.2 GO:0040016 embryonic cleavage(GO:0040016)
0.2 2.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 5.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.2 1.1 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 1.9 GO:0003139 secondary heart field specification(GO:0003139)
0.2 1.4 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 2.1 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.1 0.9 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.6 GO:0045041 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 1.4 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.9 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 1.6 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 3.0 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 1.6 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 0.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 5.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 1.0 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 1.3 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.4 GO:0051645 Golgi localization(GO:0051645)
0.1 0.7 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 2.1 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 2.3 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.0 GO:0033151 V(D)J recombination(GO:0033151)
0.1 0.6 GO:0030728 ovulation(GO:0030728)
0.1 2.2 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 1.1 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.1 0.8 GO:0061709 reticulophagy(GO:0061709)
0.1 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 2.3 GO:0016925 protein sumoylation(GO:0016925)
0.1 4.9 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 0.7 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 1.0 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.3 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 2.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.9 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.3 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 0.7 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.8 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 1.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.0 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 1.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.7 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 1.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.4 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.0 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 2.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 1.0 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.4 GO:0006264 mitochondrial DNA replication(GO:0006264) mitochondrial DNA metabolic process(GO:0032042)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.9 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.4 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.2 GO:0009648 photoperiodism(GO:0009648)
0.0 0.2 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 1.8 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 3.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.0 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 1.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.6 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 1.7 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 2.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.4 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.3 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 1.4 GO:0016573 histone acetylation(GO:0016573)
0.0 0.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.6 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.0 0.5 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.0 GO:0002902 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) lymphocyte apoptotic process(GO:0070227) regulation of lymphocyte apoptotic process(GO:0070228)
0.0 2.4 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 1.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.2 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 2.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.6 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 0.1 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0070073 regulation of melanocyte differentiation(GO:0045634) clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.6 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.5 GO:0035194 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.0 1.5 GO:0006413 translational initiation(GO:0006413)
0.0 0.7 GO:0051225 spindle assembly(GO:0051225)
0.0 0.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0072384 organelle transport along microtubule(GO:0072384)
0.0 0.8 GO:0006006 glucose metabolic process(GO:0006006)
0.0 0.4 GO:0007254 JNK cascade(GO:0007254)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.3 GO:0016525 negative regulation of angiogenesis(GO:0016525)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.5 1.9 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.5 1.8 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.4 1.2 GO:0098536 deuterosome(GO:0098536)
0.4 1.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.4 1.4 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.3 1.7 GO:1990923 PET complex(GO:1990923)
0.3 3.0 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.3 1.6 GO:0005899 insulin receptor complex(GO:0005899)
0.3 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.0 GO:0097519 DNA recombinase complex(GO:0097519)
0.2 0.7 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.2 1.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 0.5 GO:0042382 paraspeckles(GO:0042382)
0.2 0.9 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 1.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 2.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 1.2 GO:0032797 SMN complex(GO:0032797)
0.1 0.6 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.5 GO:0016589 NURF complex(GO:0016589)
0.1 0.9 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.0 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.7 GO:0016234 inclusion body(GO:0016234)
0.1 1.4 GO:0044545 NSL complex(GO:0044545)
0.1 0.7 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.4 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 1.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 4.8 GO:0005643 nuclear pore(GO:0005643)
0.1 1.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.6 GO:0072487 MSL complex(GO:0072487)
0.1 1.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.1 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.4 GO:0035517 PR-DUB complex(GO:0035517)
0.1 1.1 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614)
0.0 1.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 2.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 4.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.3 GO:0097610 cleavage furrow(GO:0032154) recycling endosome membrane(GO:0055038) cell surface furrow(GO:0097610)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 6.9 GO:0005730 nucleolus(GO:0005730)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 2.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.2 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.5 1.4 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.4 1.3 GO:1990715 mRNA CDS binding(GO:1990715)
0.3 1.6 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.3 1.1 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.3 2.4 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3 1.0 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.3 1.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 5.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 1.0 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.2 1.7 GO:0034584 piRNA binding(GO:0034584)
0.2 3.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 2.1 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.2 0.6 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.2 1.4 GO:0035173 histone kinase activity(GO:0035173)
0.2 1.2 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.1 GO:0043531 ADP binding(GO:0043531)
0.2 1.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 0.9 GO:0031852 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 0.9 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.2 2.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 0.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 2.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 3.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.0 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 1.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.7 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.5 GO:0005521 lamin binding(GO:0005521)
0.1 0.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.9 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 2.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.7 GO:0042974 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.1 0.6 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.5 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 1.6 GO:2001069 glycogen binding(GO:2001069)
0.1 4.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.9 GO:0035198 miRNA binding(GO:0035198)
0.1 2.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.4 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.1 1.2 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 2.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 2.7 GO:0019003 GDP binding(GO:0019003)
0.1 1.2 GO:0002039 p53 binding(GO:0002039)
0.1 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 3.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 1.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 0.2 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.2 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.3 GO:0031267 small GTPase binding(GO:0031267)
0.1 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.2 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 2.2 GO:0045182 translation regulator activity(GO:0045182)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 2.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 1.4 GO:0043022 ribosome binding(GO:0043022)
0.0 1.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 3.8 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0048038 quinone binding(GO:0048038)
0.0 1.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.1 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.8 GO:0017069 snRNA binding(GO:0017069)
0.0 1.1 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.9 GO:0071949 FAD binding(GO:0071949)
0.0 0.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.8 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 10.5 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.2 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 3.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 5.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 2.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.0 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 1.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 2.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.9 PID FOXO PATHWAY FoxO family signaling
0.0 0.8 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.4 5.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.3 2.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 1.0 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 2.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 1.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 1.8 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.2 0.8 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 3.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 3.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing