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PRJNA195909:zebrafish embryo and larva development

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Results for znf740b

Z-value: 1.43

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Transcription factors associated with znf740b

Gene Symbol Gene ID Gene Info
znf740b
ENSDARG00000061174 zinc finger protein 740b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf740bdr11_v1_chr23_-_36418059_36418059-0.923.9e-04Click!

Activity profile of znf740b motif

Sorted Z-values of znf740b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_24191928 3.79 ENSDART00000136827
sox12
SRY (sex determining region Y)-box 12
chr14_-_9522364 3.71 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr21_-_26495700 3.00 ENSDART00000109379
cd248b
CD248 molecule, endosialin b
chr3_-_61162750 2.92 ENSDART00000055064
pvalb8
parvalbumin 8
chr12_-_16764751 2.90 ENSDART00000113862
zgc:174154
zgc:174154
chr25_+_35502552 2.70 ENSDART00000189612
ENSDART00000058443
fibina
fin bud initiation factor a
chr5_-_14326959 2.65 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr11_-_3334248 2.52 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr12_-_16941319 2.50 ENSDART00000109968
zgc:174855
zgc:174855
chr25_+_1732838 2.48 ENSDART00000159555
ENSDART00000168161
FBLN1
fibulin 1
chr23_-_524780 2.43 ENSDART00000055139
col9a3
collagen, type IX, alpha 3
chr23_+_36101185 2.20 ENSDART00000103139
hoxc8a
homeobox C8a
chr20_+_26538137 2.07 ENSDART00000045397
stx11b.1
syntaxin 11b, tandem duplicate 1
chr25_+_37366698 2.04 ENSDART00000165400
ENSDART00000192589
slc1a2b
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr7_-_2039060 2.02 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1
chr8_+_6954984 1.95 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr13_-_45523026 1.89 ENSDART00000020663
rhd
Rh blood group, D antigen
chr14_+_33458294 1.86 ENSDART00000075278
atp1b4
ATPase Na+/K+ transporting subunit beta 4
chr6_+_52804267 1.79 ENSDART00000065681
matn4
matrilin 4
chr23_-_10175898 1.74 ENSDART00000146185
krt5
keratin 5
chr3_-_31804481 1.70 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr21_-_43117327 1.69 ENSDART00000122352
p4ha2
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr3_+_23703704 1.59 ENSDART00000024256
hoxb6a
homeobox B6a
chr2_-_16565690 1.57 ENSDART00000022549
atp1b3a
ATPase Na+/K+ transporting subunit beta 3a
chr2_+_22694382 1.56 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr23_+_32499916 1.52 ENSDART00000134811
si:dkey-261h17.1
si:dkey-261h17.1
chr1_-_38709551 1.49 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr25_+_13191391 1.48 ENSDART00000109937
si:ch211-147m6.2
si:ch211-147m6.2
chr13_-_31435137 1.47 ENSDART00000057441
rtn1a
reticulon 1a
chr21_+_30351256 1.47 ENSDART00000078341
foxi3a
forkhead box I3a
chr23_-_17470146 1.43 ENSDART00000002398
trim101
tripartite motif containing 101
chr7_-_69636502 1.42 ENSDART00000126739
tspan5a
tetraspanin 5a
chr8_+_7311478 1.40 ENSDART00000133358
ssuh2rs1
ssu-2 homolog, related sequence 1
chr20_+_20672163 1.40 ENSDART00000027758
rtn1b
reticulon 1b
chr12_+_13244149 1.38 ENSDART00000186984
ENSDART00000105896
atp2a1l
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr17_+_52822422 1.37 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr18_+_44649804 1.35 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr20_+_25340814 1.33 ENSDART00000063028
ctgfa
connective tissue growth factor a
chr2_+_43469241 1.32 ENSDART00000142078
ENSDART00000098265
nrp1b
neuropilin 1b
chr2_-_23004286 1.31 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr20_-_35246150 1.26 ENSDART00000090549
fzd3a
frizzled class receptor 3a
chr12_-_4540564 1.26 ENSDART00000106566
CABZ01030107.1

chr4_-_5597167 1.25 ENSDART00000132431
vegfab
vascular endothelial growth factor Ab
chr3_+_40809011 1.22 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr12_+_42436328 1.20 ENSDART00000167324
ebf3a
early B cell factor 3a
chr23_+_42434348 1.20 ENSDART00000161027
cyp2aa1
cytochrome P450, family 2, subfamily AA, polypeptide 1
chr7_-_48665305 1.19 ENSDART00000190507
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr11_-_97817 1.18 ENSDART00000092903
elmo2
engulfment and cell motility 2
chr22_+_28446557 1.18 ENSDART00000089546
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr2_-_44183613 1.14 ENSDART00000079596
cadm3
cell adhesion molecule 3
chr2_-_44183451 1.14 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr22_+_28446365 1.13 ENSDART00000189359
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr1_-_42778510 1.12 ENSDART00000190172
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr19_+_5315987 1.11 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr10_+_8968203 1.10 ENSDART00000110443
ENSDART00000080772
fstb
follistatin b
chr9_-_18877597 1.09 ENSDART00000099446
kctd4
potassium channel tetramerization domain containing 4
chr15_-_5815006 1.09 ENSDART00000102459
rbp2a
retinol binding protein 2a, cellular
chr5_-_16351306 1.08 ENSDART00000168643
CABZ01088700.1

chr25_+_25464630 1.08 ENSDART00000150537
rassf7a
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr18_+_45990394 1.08 ENSDART00000024068
mmp23bb
matrix metallopeptidase 23bb
chr4_+_76619791 1.06 ENSDART00000184042
ms4a17a.8
membrane-spanning 4-domains, subfamily A, member 17A.8
chr25_-_11088839 1.06 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr11_-_497854 1.05 ENSDART00000104520
cnbpb
CCHC-type zinc finger, nucleic acid binding protein b
chr7_+_71335815 1.05 ENSDART00000102756
sod3a
superoxide dismutase 3, extracellular a
chr19_+_42983613 1.04 ENSDART00000033724
fabp3
fatty acid binding protein 3, muscle and heart
chr10_-_43540196 1.03 ENSDART00000170891
si:ch73-215f7.1
si:ch73-215f7.1
chr21_+_7823146 1.03 ENSDART00000030579
crhbp
corticotropin releasing hormone binding protein
chr23_+_44580254 1.02 ENSDART00000185069
pfn1
profilin 1
chr11_+_38280454 1.01 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr21_+_19648814 1.01 ENSDART00000048581
fgf10a
fibroblast growth factor 10a
chr16_-_8280885 0.99 ENSDART00000129068
entpd3
ectonucleoside triphosphate diphosphohydrolase 3
chr7_-_27686021 0.99 ENSDART00000079112
ENSDART00000100989
calca
calcitonin/calcitonin-related polypeptide, alpha
chr5_-_40510397 0.98 ENSDART00000146237
ENSDART00000051065
fsta
follistatin a
chr3_-_1190132 0.96 ENSDART00000149709
smdt1a
single-pass membrane protein with aspartate-rich tail 1a
chr3_-_16289826 0.95 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr1_+_39553040 0.93 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr1_-_42779075 0.93 ENSDART00000133917
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr9_+_5862040 0.93 ENSDART00000129117
pdzk1
PDZ domain containing 1
chr8_-_23776399 0.93 ENSDART00000114800
INAVA
si:ch211-163l21.4
chr5_-_71838520 0.92 ENSDART00000174396
CU927890.1

chr2_+_23790748 0.92 ENSDART00000041877
csrnp1a
cysteine-serine-rich nuclear protein 1a
chr10_-_43113731 0.92 ENSDART00000138099
tmem167a
transmembrane protein 167A
chr10_-_43294933 0.91 ENSDART00000062631
hapln1b
hyaluronan and proteoglycan link protein 1b
chr3_+_50312422 0.90 ENSDART00000157689
gas7a
growth arrest-specific 7a
chr23_-_19715557 0.90 ENSDART00000143764
rpl10
ribosomal protein L10
chr25_+_13191615 0.88 ENSDART00000168849
si:ch211-147m6.2
si:ch211-147m6.2
chr24_-_37877743 0.85 ENSDART00000105658
tmem204
transmembrane protein 204
chr7_-_35126374 0.84 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr16_+_22587661 0.84 ENSDART00000129612
ENSDART00000142241
she
Src homology 2 domain containing E
chr5_+_30699260 0.83 ENSDART00000012888
atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr17_-_36988455 0.82 ENSDART00000187180
ENSDART00000126823
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr18_+_21122818 0.81 ENSDART00000060015
ENSDART00000060184
chka
choline kinase alpha
chr16_+_10918252 0.80 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr10_+_10210455 0.78 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr5_-_41841675 0.76 ENSDART00000141683
si:dkey-65b12.6
si:dkey-65b12.6
chr12_-_20584413 0.76 ENSDART00000170923
FP885542.2

chr22_-_15957041 0.76 ENSDART00000149236
ENSDART00000187500
ENSDART00000176304
ENSDART00000080047
ENSDART00000190068
eps15l1a
epidermal growth factor receptor pathway substrate 15-like 1a
chr2_-_6051836 0.76 ENSDART00000092479
si:ch211-284b7.3
si:ch211-284b7.3
chr24_+_41931585 0.76 ENSDART00000130310
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr9_-_32753535 0.73 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr11_-_18705303 0.72 ENSDART00000059732
id1
inhibitor of DNA binding 1
chr24_-_21674950 0.72 ENSDART00000123216
ENSDART00000046211
lnx2a
ligand of numb-protein X 2a
chr13_+_23677949 0.70 ENSDART00000144215
pcnxl2
pecanex-like 2 (Drosophila)
chr8_+_8291492 0.70 ENSDART00000151314
srpk3
SRSF protein kinase 3
chr23_+_36083529 0.69 ENSDART00000053295
ENSDART00000130260
hoxc10a
homeobox C10a
chr16_+_10963602 0.69 ENSDART00000141032
pou2f2a
POU class 2 homeobox 2a
chr18_-_34549721 0.69 ENSDART00000137101
ENSDART00000021880
ssr3
signal sequence receptor, gamma
chr19_+_2279051 0.68 ENSDART00000182103
itgb8
integrin, beta 8
chr20_-_16972351 0.68 ENSDART00000148312
ENSDART00000186702
si:ch73-74h11.1
si:ch73-74h11.1
chr7_+_38249858 0.67 ENSDART00000150158
si:dkey-78a14.4
si:dkey-78a14.4
chr22_+_35068046 0.67 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
si:ch73-173h19.3
chr17_-_20849879 0.66 ENSDART00000088100
ENSDART00000149630
ank3b
ankyrin 3b
chr3_+_62126981 0.65 ENSDART00000060527
drc3
dynein regulatory complex subunit 3
chr19_+_48117995 0.65 ENSDART00000170865
nme2b.1
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr23_+_5977965 0.64 ENSDART00000115403
ENSDART00000183147
NAV1 (1 of many)
neuron navigator 1
chr15_-_5742531 0.63 ENSDART00000045985
phkg1a
phosphorylase kinase, gamma 1a (muscle)
chr19_+_35799384 0.63 ENSDART00000076023
angpt2b
angiopoietin 2b
chr3_-_33417826 0.62 ENSDART00000084284
abi3a
ABI family, member 3a
chr21_+_25660613 0.62 ENSDART00000134017
si:dkey-17e16.15
si:dkey-17e16.15
chr23_+_6232895 0.61 ENSDART00000139795
syt2a
synaptotagmin IIa
chr1_+_27070760 0.61 ENSDART00000186790
bnc2
basonuclin 2
chr3_-_26204867 0.61 ENSDART00000103748
gdpd3a
glycerophosphodiester phosphodiesterase domain containing 3a
chr25_-_37501371 0.61 ENSDART00000160498
CABZ01088346.1

chr9_+_12959760 0.60 ENSDART00000125961
bmpr2b
bone morphogenetic protein receptor, type II b (serine/threonine kinase)
chr4_+_12612145 0.60 ENSDART00000181201
lmo3
LIM domain only 3
chr10_-_31563049 0.60 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr18_+_35742838 0.59 ENSDART00000088504
ENSDART00000140386
rasgrp4
RAS guanyl releasing protein 4
chr5_+_32162684 0.59 ENSDART00000134472
taok3b
TAO kinase 3b
chr8_-_23578660 0.59 ENSDART00000039080
wasb
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr10_+_2742499 0.59 ENSDART00000122847
grk5
G protein-coupled receptor kinase 5
chr6_+_54239625 0.58 ENSDART00000149542
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr17_-_12389259 0.58 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr7_+_61480296 0.58 ENSDART00000083255
adam19a
ADAM metallopeptidase domain 19a
chr7_-_57949117 0.58 ENSDART00000138803
ank2b
ankyrin 2b, neuronal
chr1_-_51474974 0.57 ENSDART00000152719
spred2a
sprouty-related, EVH1 domain containing 2a
chr21_+_19635486 0.57 ENSDART00000185736
fgf10a
fibroblast growth factor 10a
chr2_+_28889936 0.56 ENSDART00000078232
cdh10a
cadherin 10, type 2a (T2-cadherin)
chr10_-_35542071 0.56 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr2_+_47623202 0.55 ENSDART00000154465
si:ch211-165b10.3
si:ch211-165b10.3
chr9_-_31278048 0.55 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr20_-_37629084 0.55 ENSDART00000141734
hivep2a
human immunodeficiency virus type I enhancer binding protein 2a
chr23_-_41651759 0.54 ENSDART00000146808
si:ch73-184c24.1
si:ch73-184c24.1
chr23_+_20931030 0.54 ENSDART00000167014
pax7b
paired box 7b
chr1_-_44638058 0.54 ENSDART00000081835
slc43a1b
solute carrier family 43 (amino acid system L transporter), member 1b
chr1_-_52498146 0.54 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr24_-_28243186 0.54 ENSDART00000105691
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr12_+_22258962 0.54 ENSDART00000131175
wnt3
wingless-type MMTV integration site family, member 3
chr20_-_42100932 0.54 ENSDART00000191930
slc35f1
solute carrier family 35, member F1
chr16_-_41439659 0.53 ENSDART00000191624
cpne4a
copine IVa
chr24_-_21808816 0.52 ENSDART00000025621
ENSDART00000130446
flt1
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
chr7_+_46261199 0.52 ENSDART00000170390
ENSDART00000183227
znf536
zinc finger protein 536
chr24_-_40860603 0.51 ENSDART00000188032
CU633479.7

chr25_-_18470695 0.51 ENSDART00000034377
cpa5
carboxypeptidase A5
chr3_+_21189766 0.50 ENSDART00000078807
zgc:123295
zgc:123295
chr4_+_11311315 0.50 ENSDART00000051792
sema3aa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa
chr1_+_31112436 0.50 ENSDART00000075340
eef1a1b
eukaryotic translation elongation factor 1 alpha 1b
chr21_-_11820379 0.49 ENSDART00000126640
RHOBTB3
si:dkey-6b12.5
chr8_+_36803415 0.48 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr12_-_7854216 0.48 ENSDART00000149594
ank3b
ankyrin 3b
chr16_-_31435020 0.47 ENSDART00000138508
zgc:194210
zgc:194210
chr11_-_4235811 0.47 ENSDART00000121716
si:ch211-236d3.4
si:ch211-236d3.4
chr21_+_5635420 0.47 ENSDART00000168158
shroom3
shroom family member 3
chr11_+_6650966 0.47 ENSDART00000131236
si:dkey-246j7.1
si:dkey-246j7.1
chr13_-_638485 0.46 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr7_+_36552725 0.46 ENSDART00000173682
chd9
chromodomain helicase DNA binding protein 9
chr5_-_68022631 0.46 ENSDART00000143199
wasf3a
WAS protein family, member 3a
chr6_+_38381957 0.45 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr21_-_37889727 0.45 ENSDART00000163612
ENSDART00000180958
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr1_+_53842344 0.45 ENSDART00000114506
crfb17
cytokine receptor family member B17
chr21_+_42930558 0.44 ENSDART00000135234
stk32a
serine/threonine kinase 32A
chr9_+_8942258 0.44 ENSDART00000138836
ankrd10b
ankyrin repeat domain 10b
chr5_-_70625697 0.43 ENSDART00000179538
ENSDART00000190540
CABZ01075572.1

chr13_-_25198025 0.43 ENSDART00000159585
ENSDART00000144227
adka
adenosine kinase a
chr6_+_23712911 0.43 ENSDART00000167795
zgc:158654
zgc:158654
chr3_-_52614747 0.43 ENSDART00000154365
trim35-13
tripartite motif containing 35-13
chr21_+_5589923 0.43 ENSDART00000160885
stbd1
starch binding domain 1
chr12_+_5530247 0.42 ENSDART00000114637
ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr19_-_25519310 0.42 ENSDART00000089882
C1GALT1 (1 of many)
si:dkey-202e17.1
chr12_+_24561832 0.42 ENSDART00000088159
nrxn1a
neurexin 1a
chr6_-_37460178 0.41 ENSDART00000153500
si:dkey-66a8.7
si:dkey-66a8.7
chr16_-_23800484 0.41 ENSDART00000139964
rps27.2
ribosomal protein S27, isoform 2
chr2_-_26527730 0.41 ENSDART00000138693
si:ch211-106k21.5
si:ch211-106k21.5
chr1_+_51475094 0.41 ENSDART00000146352
meis1a
Meis homeobox 1 a
chr15_-_35246742 0.40 ENSDART00000131479
mff
mitochondrial fission factor
chr15_+_3284416 0.40 ENSDART00000187665
ENSDART00000171723
foxo1a
forkhead box O1 a
chr8_+_8936912 0.38 ENSDART00000135958
si:dkey-83k24.5
si:dkey-83k24.5
chr18_-_16181952 0.38 ENSDART00000157824
slc6a15
solute carrier family 6 (neutral amino acid transporter), member 15
chr4_+_34417403 0.37 ENSDART00000186032
ENSDART00000167909
si:ch211-246b8.2
si:ch211-246b8.2
chr4_+_3980247 0.37 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr6_+_15373153 0.36 ENSDART00000155865
tmtops2a
teleost multiple tissue opsin 2a
chr3_+_6469754 0.35 ENSDART00000185809
NUP85 (1 of many)
nucleoporin 85
chr15_-_12229874 0.35 ENSDART00000165159
dscaml1
Down syndrome cell adhesion molecule like 1
chr24_-_37877554 0.34 ENSDART00000132219
tmem204
transmembrane protein 204
chr19_-_25519612 0.34 ENSDART00000133150
C1GALT1 (1 of many)
si:dkey-202e17.1
chr19_-_46957968 0.34 ENSDART00000043713
angpt1
angiopoietin 1
chr17_-_22062364 0.33 ENSDART00000114470
ttbk1b
tau tubulin kinase 1b
chr10_+_42159471 0.32 ENSDART00000122160
CR925773.1

chr23_+_9353552 0.32 ENSDART00000163298
BX511246.1

chr20_-_28642061 0.31 ENSDART00000135513
rgs6
regulator of G protein signaling 6
chr9_+_7358749 0.31 ENSDART00000081660
ihha
Indian hedgehog homolog a

Network of associatons between targets according to the STRING database.

First level regulatory network of znf740b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.5 2.6 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.4 1.6 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.4 1.5 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 1.0 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.3 0.9 GO:1990403 embryonic brain development(GO:1990403)
0.2 1.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.9 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 0.9 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.2 1.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.2 2.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 0.7 GO:0021742 abducens nucleus development(GO:0021742)
0.2 1.2 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 1.3 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.1 1.4 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.8 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 0.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.2 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.5 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 1.0 GO:0019430 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.5 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.7 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.6 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.4 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.6 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 1.7 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 1.6 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 2.0 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.1 0.3 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 0.2 GO:0060031 mediolateral intercalation(GO:0060031)
0.1 2.7 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.4 GO:0044209 AMP salvage(GO:0044209)
0.1 0.4 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.5 GO:0021794 thalamus development(GO:0021794)
0.1 1.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 1.0 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.1 0.8 GO:0051963 regulation of synapse assembly(GO:0051963)
0.1 1.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 2.2 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.6 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 1.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 1.0 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.8 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.8 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.1 GO:0042476 odontogenesis(GO:0042476)
0.0 1.1 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.3 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 0.3 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 1.5 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.5 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 1.1 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.7 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.2 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.6 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0001843 neural tube closure(GO:0001843)
0.0 1.2 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.2 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.7 GO:0031101 fin regeneration(GO:0031101)
0.0 0.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.1 GO:0009306 protein secretion(GO:0009306)
0.0 1.3 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0060612 adipose tissue development(GO:0060612)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 1.7 GO:0045095 keratin filament(GO:0045095)
0.1 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 2.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.0 GO:1990246 uniplex complex(GO:1990246)
0.1 1.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 4.2 GO:0005882 intermediate filament(GO:0005882)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.0 0.8 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0030315 T-tubule(GO:0030315)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.9 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.9 GO:0016607 nuclear speck(GO:0016607)
0.0 7.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 5.1 GO:0005764 lysosome(GO:0005764)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 1.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.7 GO:0008305 integrin complex(GO:0008305)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.5 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.3 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 2.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 1.0 GO:0031716 calcitonin receptor binding(GO:0031716)
0.3 1.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 0.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 1.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.7 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 1.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 2.1 GO:0048185 activin binding(GO:0048185)
0.1 0.4 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 0.4 GO:2001070 starch binding(GO:2001070)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.9 GO:0043495 protein anchor(GO:0043495)
0.1 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.0 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0019767 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.0 0.1 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.2 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.0 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 4.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 2.3 GO:0015293 symporter activity(GO:0015293)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.7 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.0 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 3.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.5 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane